CN105816807A - Anti-aging traditional Chinese medicine composition containing scrophularia ningpoensis for cosmetics - Google Patents
Anti-aging traditional Chinese medicine composition containing scrophularia ningpoensis for cosmetics Download PDFInfo
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The invention discloses an anti-aging traditional Chinese medicine composition containing scrophularia ningpoensis for cosmetics. The composition is prepared from the following raw materials in parts by weight: 15-20 parts of selfheal, 10-20 parts of scrophularia ningpoensis, 10-15 parts of liquorice, 20-30 parts of passion fruits, 5-10 parts of turmeric, 5-10 parts of lalang grass rhizome and 10-15 parts of ficus pumila. According to the composition, through the synergistic effect among the raw materials, the anti-aging effect of the composition is increased; the composition is compounded by purely natural plant extracts with a mild medicine effect; the composition is small in side effect, wide in adaptability and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae.
Background technology
Along with improving constantly of people's living standard, everybody also begins to pay close attention to other aspects, the such as appearance of oneself after meeting basic clothing, food, lodging and transportion--basic necessities of life demand.Pursuit to the oldest appearance occurs the most until now in fact, from ancient times to the present, from man to female, from west to east, from Black people to white man, is the most all seeking this possibility.Along with science and technology development, it is achieved probability also gradually step up, anti-aging cosmetics is the most increasingly paid close attention to by people.
Skin is the most all aging, and its elasticity slowly reduces, and thin down, more and more fragile and lax, be wrinkled exactly to the visual impression of people.According to the Aging Mechanism of skin, the approach of defying age can be inquired into.Sum up and specifically include that protecting the skin from external environment stimulates；Unnecessary free radical in scavenger cell；Skin Cell is repaired and supplements the nutrients.Skin anti-aging is to prevent skin from occurring the function of gradually property and organic moving back to sexually revise because of time passage, shows as preventing wrinkle, dry, a bits, lax and mottle.Anti-aging cosmetics is exactly the cosmetics realizing senile-resistant efficacy, is one of important effect type cosmetics.
Anti-aging cosmetics substantially can be divided three classes by its function or effect difference, respectively humidity-preserving type cosmetic, anti-oxidative cosmetics and biological activity cosmetics.Activated feedstock in variety classes cosmetics is different, the most perfect along with what bioactive ingredients was studied, the kind of activated feedstock is more and more abundanter, and the activated feedstock being applied in anti-aging cosmetics is more and more numerous and diverse, but the application of the most numerous and diverse activated feedstock, make cosmetic composition more complicated, various side reactions are difficult to control to and detect, and cause cosmetics side effect to increase, worse to the adaptability of different skin quality skins, and cost is high, and anti-aging effects is poor.Therefore, invention one has that anti-aging effects is good, side effect is little, and the Chinese medicine composition of wide adaptability is to the development of cosmetic industry and to improve the living standard of people the most significant.
Summary of the invention
It is an object of the invention to overcome the deficiency that anti-aging effects is poor, side effect is big in the presence of prior art, it is provided that a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae.Said composition, by the chemiluminescence between raw material, adds the anti-aging effects of compositions, and drug effect is gentle, pure natural plant extract combines, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, said composition is to be prepared from by the raw material of following weight: Spica Prunellae 15-20 part, Radix Scrophulariae 10-20 part, Radix Glycyrrhizae 10-15 part, Passiflora edulis sims 20-30 part, Rhizoma Curcumae Longae 5-10 part, Rhizoma Imperatae 5-10 part, Caulis fici pumilae (Fructus Fici Pumilae) 10-15 part.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, wherein said Spica Prunellae, acrid in the mouth, hardship, cold in nature.Return liver, gallbladder meridian.Spica Prunellae contains the glycoside materials such as triterpene saponin, rutin, hyperin. also contain the organic acid such as ursolic acid, caffeic acid and free oleanolic acid.There is clearing away heat-fire, improving eyesight, the drug effect of mass dissipating and swelling eliminating.
Wherein said Radix Scrophulariae, sweet in the mouth, hardship, salty, cold nature.Return spleen, stomach, kidney channel.Cure mainly warm febrile disease and nutrient blood；Fever of the body；Excessive thirst；Crimson tongue；Send out speckle；Hectic fever due to YIN-deficiency chronic cough；Fidgets due to deficiency not awake；Constipation is hindered in Tianjin；Mesh is puckery dim-sighted；Throat larynx swells and ache；Scrofula sucutaneous nodule；Skin sore.
Wherein said Radix Glycyrrhizae, property is flat, and sweet in the mouth returns 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Wherein said Passiflora edulis sims, sweet in the mouth, acid；Property flat.GUIXIN, large intestine channel.There is clearing away lung-heat and moistening for dryness；Ataralgesia；Drug effect with blood dysentery relieving.Cure mainly cough；Dry pharynx；Hoarseness；Constipation；Insomnia；Dysmenorrhea；Arthralgia；Dysentery.There is purification body, it is to avoid harmful substance deposits in vivo, and then reach to improve skin, beautify the effect of appearance, immunity, slow down aging can be improved.
Wherein said Rhizoma Curcumae Longae, acrid in the mouth, hardship, warm in nature.GUIXIN, spleen channel.There is removing blood stasis, circulation of qi promoting, stimulate the menstrual flow, effect of pain relieving.Controlling trusted subordinate's feeling of fullness distending pain, brachialgia, lump in the abdomen, women's blood stasis amenorrhea, puerperal, the stasis of blood stopped stomachache, injury from falling down, carbuncle.Chest and abdomen pain, dysmenorrhea and limbs pain for qi depression to blood stasis.The curcumin contained has antioxidation.
Wherein said Rhizoma Imperatae, sweet in the mouth, cold in nature.Root contains Triterpenoid arundoin, Cylindrin, fernenol, isoarborinol, simiarenol, fern ketenes, arborinol, freidelin etc..Cure mainly haematemesis, epistaxis, hematuria, dysuria, urine pyretic stranguria, regurgitation, the puckery pain of pyretic stranguria, acute nephritis, edema, jaundice due to damp-heat, gastropyretic vomiting, cough due to lung-heat, asthma.
Wherein said Caulis fici pumilae (Fructus Fici Pumilae), sour in the mouth, property is put down.Containing uvaol, betula camphor, bean steroid-5,24(28)-diene-3 β-ol, 5 α-bean steroid-3,6-diketone, cupreol, Betulinic Acid, daucosterol, lupeol, stigmasterol, n-hexacosane alcohol etc..Have and dispel the wind, dampness removing, invigorate blood circulation, removing toxic substances, the effect of antiinflammatory.Treatment phoenix pain of dampness syndrome, dysentery, gonorrhea, traumatic injury, carbuncle furuncle.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, preferably, said composition is to be prepared from by the raw material of following weight: Spica Prunellae 18-20 part, Radix Scrophulariae 10-15 part, Radix Glycyrrhizae 12-15 part, Passiflora edulis sims 25-30 part, Rhizoma Curcumae Longae 8-10 part, Rhizoma Imperatae 5-8 part, Caulis fici pumilae (Fructus Fici Pumilae) 12-15 part；It is further preferred that said composition is to be prepared from by the raw material of following weight: Spica Prunellae 18 parts, Radix Scrophulariae 15 parts, 13 parts of Radix Glycyrrhizae, Passiflora edulis sims 28 parts, 9 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 6 parts, Caulis fici pumilae (Fructus Fici Pumilae) 14 parts.Preferably can make the synergistic function maximum of compositions by above-mentioned, anti-aging effects reaches optimal, and side effect is minimum.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, in addition to above-mentioned necessary raw material, also can add auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water etc. according to actual needs.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, can make cosmetics with conventional base material by arbitrary proportion, and State of cosmetics can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, said composition is made up of the natural material of multiple gentleness, synergistic function by active component different in each raw material, excite the activity of activity of fighting against senium material therein the most greatly, and drug effect is gentle, have no side effect, be suitable for all kinds of skin quality, skin is high to the absorption efficiency of defying age active matter, and anti-aging effects is notable.
Further, the invention provides the preparation method of a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, its concrete preparation process is as follows:
1, by Spica Prunellae, Radix Scrophulariae, Radix Glycyrrhizae, Passiflora edulis sims, Rhizoma Curcumae Longae, Rhizoma Imperatae, Caulis fici pumilae (Fructus Fici Pumilae) is pulverized after being separately dried, and extracts with ethanol solution and concentrates, and obtains Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, the Spica Prunellae extracting solution of step 1 gained, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution are carried out maturation process respectively, mix homogeneously after cooling, and again carry out filtering, purifying, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age.
The preparation method of above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, wherein to Spica Prunellae in step 1, Radix Scrophulariae, Radix Glycyrrhizae, Passiflora edulis sims, Rhizoma Curcumae Longae, Rhizoma Imperatae, the extraction of Caulis fici pumilae (Fructus Fici Pumilae), method for concentration are conventional plant extract, method for concentration, can be separated by the active ingredient of the defying age in plant, and increase activity component concentration, improve anti-aging effects.
The preparation method of above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, wherein step 2 carries out maturation process respectively to Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution, i.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in plant, reduce side effect, improve the adaptability to different skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin.
Wherein, in described curing process, the cooking conditions to each raw material is different, can be under conditions of the activity farthest ensureing activity of fighting against senium composition, destroy the easy allergin in plant, reduce side effect, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin, its temperature, pressure and time specifically chosen as follows:
| Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
| Spica Prunellae | 68-70 | 0.2-0.4 | 1-2 |
| Radix Scrophulariae | 88-93 | 0.2-0.3 | 4-5 |
| Radix Glycyrrhizae | 75-80 | 0.4-0.5 | 3-4 |
| Passiflora edulis sims | 65-70 | 0.1-0.2 | 0.5-1 |
| Rhizoma Curcumae Longae | 82-85 | 0.1-0.2 | 2-3 |
| Rhizoma Imperatae | 71-75 | 0.2-0.3 | 2-3 |
| Caulis fici pumilae (Fructus Fici Pumilae) | 63-65 | 0.1-0.2 | 1-2 |
The preparation method of above-mentioned a kind of delay aging drug compositions for cosmetics containing Radix Scrophulariae, by to the ripening at different conditions of different material extracting solution, easy allergin in raw material extracting solution is inactivated or decomposes, and retain the active component of the defying age of energy Synergistic, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only reduce the allergy probability of Chinese medicine composition, improve adaptability, can also improve the absorption efficiency of skin, anti-aging effects is more preferable.
Compared with prior art, beneficial effects of the present invention:
1, the present composition is by the synergistic function of active component different in each raw material, excites the activity of activity of fighting against senium material therein greatly, and anti-aging effects is good.
2, the present composition selects multiple gentle preparation of raw material to form, and drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, more preferable to the permeability of skin, is easily absorbed by the skin, improves anti-aging effects.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easy anaphylaxis and side reaction, improves the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should not being interpreted as, the scope of the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to the scope of the present invention.
Embodiment 1
1, by Spica Prunellae 18 parts, Radix Scrophulariae 15 parts, 13 parts of Radix Glycyrrhizae, Passiflora edulis sims 28 parts, 9 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 6 parts, Caulis fici pumilae (Fructus Fici Pumilae) 14 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 69 DEG C, carry out after carrying out ripening 1h under 0.3MPa pressure filtering, purifying, cool down to obtain Spica Prunellae essence；By the Radix Scrophulariae extracting solution of step 1 gained at 90 DEG C, carry out after carrying out ripening 5h under 0.2MPa pressure filtering, purifying, cool down to obtain Radix Scrophulariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the Passiflora edulis sims extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Passiflora edulis sims essence；By the Rhizoma Curcumae Longae extracting solution of step 1 gained at 84 DEG C, carry out after carrying out ripening 3h under 0.1MPa pressure filtering, purifying, cool down to obtain Rhizoma Curcumae Longae essence；By the Rhizoma Imperatae extracting solution of step 1 gained at 74 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Imperatae essence；By the Caulis fici pumilae (Fructus Fici Pumilae) extracting solution of step 1 gained at 64 DEG C, carry out after carrying out ripening 2h under 0.1MPa pressure filtering, purifying, cool down to obtain Caulis fici pumilae (Fructus Fici Pumilae) essence；By the Spica Prunellae essence of gained, Radix Scrophulariae essence, Radix Glycyrrhizae essence, Passiflora edulis sims essence, Rhizoma Curcumae Longae essence, Rhizoma Imperatae essence, Caulis fici pumilae (Fructus Fici Pumilae) essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
It is good that this cosmetic emulsion has anti-aging effects, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 2
1, by Spica Prunellae 20 parts, Radix Scrophulariae 10 parts, 10 parts of Radix Glycyrrhizae, Passiflora edulis sims 30 parts, 5 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 10 parts, Caulis fici pumilae (Fructus Fici Pumilae) 10 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 2h under 0.4MPa pressure filtering, purifying, cool down to obtain Spica Prunellae essence；By the Radix Scrophulariae extracting solution of step 1 gained at 93 DEG C, carry out after carrying out ripening 5h under 0.3MPa pressure filtering, purifying, cool down to obtain Radix Scrophulariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 75 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the Passiflora edulis sims extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain Passiflora edulis sims essence；By the Rhizoma Curcumae Longae extracting solution of step 1 gained at 82 DEG C, carry out after carrying out ripening 2h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Curcumae Longae essence；By the Rhizoma Imperatae extracting solution of step 1 gained at 71 DEG C, carry out after carrying out ripening 3h under 0.3MPa pressure filtering, purifying, cool down to obtain Rhizoma Imperatae essence；By the Caulis fici pumilae (Fructus Fici Pumilae) extracting solution of step 1 gained at 63 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain Caulis fici pumilae (Fructus Fici Pumilae) essence；By the Spica Prunellae essence of gained, Radix Scrophulariae essence, Radix Glycyrrhizae essence, Passiflora edulis sims essence, Rhizoma Curcumae Longae essence, Rhizoma Imperatae essence, Caulis fici pumilae (Fructus Fici Pumilae) essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
It is good that this cosmetic emulsion has anti-aging effects, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 3
1, by Spica Prunellae 15 parts, Radix Scrophulariae 20 parts, 10 parts of Radix Glycyrrhizae, Passiflora edulis sims 20 parts, 10 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 10 parts, Caulis fici pumilae (Fructus Fici Pumilae) 15 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain Spica Prunellae essence；By the Radix Scrophulariae extracting solution of step 1 gained at 88 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain Radix Scrophulariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 80 DEG C, carry out after carrying out ripening 3h under 0.4MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the Passiflora edulis sims extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 0.5h under 0.1MPa pressure filtering, purifying, cool down to obtain Passiflora edulis sims essence；By the Rhizoma Curcumae Longae extracting solution of step 1 gained at 85 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Curcumae Longae essence；By the Rhizoma Imperatae extracting solution of step 1 gained at 75 DEG C, carry out after carrying out ripening 3h under 0.3MPa pressure filtering, purifying, cool down to obtain Rhizoma Imperatae essence；By the Caulis fici pumilae (Fructus Fici Pumilae) extracting solution of step 1 gained at 63 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain Caulis fici pumilae (Fructus Fici Pumilae) essence；By the Spica Prunellae essence of gained, Radix Scrophulariae essence, Radix Glycyrrhizae essence, Passiflora edulis sims essence, Rhizoma Curcumae Longae essence, Rhizoma Imperatae essence, Caulis fici pumilae (Fructus Fici Pumilae) essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
It is good that this cosmetic emulsion has anti-aging effects, has no side effect, the advantage of suitable various skin skin quality.
Comparative example 1
1, by Spica Prunellae 18 parts, Radix Scrophulariae 15 parts, 13 parts of Radix Glycyrrhizae, Passiflora edulis sims 28 parts, 9 parts of Rhizoma Curcumae Longae, Caulis fici pumilae (Fructus Fici Pumilae) 14 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 69 DEG C, carry out after carrying out ripening 1h under 0.3MPa pressure filtering, purifying, cool down to obtain Spica Prunellae essence；By the Radix Scrophulariae extracting solution of step 1 gained at 90 DEG C, carry out after carrying out ripening 5h under 0.2MPa pressure filtering, purifying, cool down to obtain Radix Scrophulariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the Passiflora edulis sims extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Passiflora edulis sims essence；By the Rhizoma Curcumae Longae extracting solution of step 1 gained at 84 DEG C, carry out after carrying out ripening 3h under 0.1MPa pressure filtering, purifying, cool down to obtain Rhizoma Curcumae Longae essence；By the Caulis fici pumilae (Fructus Fici Pumilae) extracting solution of step 1 gained at 64 DEG C, carry out after carrying out ripening 2h under 0.1MPa pressure filtering, purifying, cool down to obtain Caulis fici pumilae (Fructus Fici Pumilae) essence；By the Spica Prunellae essence of gained, Radix Scrophulariae essence, Radix Glycyrrhizae essence, Passiflora edulis sims essence, Rhizoma Curcumae Longae essence, Caulis fici pumilae (Fructus Fici Pumilae) essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
Comparative example 2
1, by Radix Scrophulariae 15 parts, 13 parts of Radix Glycyrrhizae, Passiflora edulis sims 28 parts, 9 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 6 parts, Caulis fici pumilae (Fructus Fici Pumilae) 14 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by the Radix Scrophulariae extracting solution of step 1 gained at 90 DEG C, carry out after carrying out ripening 5h under 0.2MPa pressure filtering, purifying, cool down to obtain Radix Scrophulariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the Passiflora edulis sims extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Passiflora edulis sims essence；By the Rhizoma Curcumae Longae extracting solution of step 1 gained at 84 DEG C, carry out after carrying out ripening 3h under 0.1MPa pressure filtering, purifying, cool down to obtain Rhizoma Curcumae Longae essence；By the Rhizoma Imperatae extracting solution of step 1 gained at 74 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Imperatae essence；By the Caulis fici pumilae (Fructus Fici Pumilae) extracting solution of step 1 gained at 64 DEG C, carry out after carrying out ripening 2h under 0.1MPa pressure filtering, purifying, cool down to obtain Caulis fici pumilae (Fructus Fici Pumilae) essence；By the Radix Scrophulariae essence of gained, Radix Glycyrrhizae essence, Passiflora edulis sims essence, Rhizoma Curcumae Longae essence, Rhizoma Imperatae essence, Caulis fici pumilae (Fructus Fici Pumilae) essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
Comparative example 3
1, by Spica Prunellae 25 parts, Radix Scrophulariae 25 parts, 10 parts of Radix Glycyrrhizae, Passiflora edulis sims 15 parts, 5 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 15 parts, Caulis fici pumilae (Fructus Fici Pumilae) 5 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 69 DEG C, carry out after carrying out ripening 1h under 0.3MPa pressure filtering, purifying, cool down to obtain Spica Prunellae essence；By the Radix Scrophulariae extracting solution of step 1 gained at 90 DEG C, carry out after carrying out ripening 5h under 0.2MPa pressure filtering, purifying, cool down to obtain Radix Scrophulariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the Passiflora edulis sims extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Passiflora edulis sims essence；By the Rhizoma Curcumae Longae extracting solution of step 1 gained at 84 DEG C, carry out after carrying out ripening 3h under 0.1MPa pressure filtering, purifying, cool down to obtain Rhizoma Curcumae Longae essence；By the Rhizoma Imperatae extracting solution of step 1 gained at 74 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Imperatae essence；By the Caulis fici pumilae (Fructus Fici Pumilae) extracting solution of step 1 gained at 64 DEG C, carry out after carrying out ripening 2h under 0.1MPa pressure filtering, purifying, cool down to obtain Caulis fici pumilae (Fructus Fici Pumilae) essence；By the Spica Prunellae essence of gained, Radix Scrophulariae essence, Radix Glycyrrhizae essence, Passiflora edulis sims essence, Rhizoma Curcumae Longae essence, Rhizoma Imperatae essence, Caulis fici pumilae (Fructus Fici Pumilae) essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
Comparative example 4
1, by Spica Prunellae 15 parts, Radix Scrophulariae 11 parts, 12 parts of Radix Glycyrrhizae, Passiflora edulis sims 16 parts, 8 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 9 parts, Caulis fici pumilae (Fructus Fici Pumilae) 12 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2, by Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
The anti-aging cosmetics that above-described embodiment 1-3 and comparative example 1-4 obtain is tried out, randomly choose 800 volunteers, it is divided into 8 groups, wherein 1-7 uses the cosmetics that embodiment and comparative example prepare respectively, select the anti-aging cosmetics that commercial type is best for 8th group, after using 15 days, skin detected and contrast, obtaining data below:
| Test group | Allergy number | TYR enzyme inhibition rate (%) | Superoxide anion clearance (%) | Hydroxy radical ion remaval rate (%) |
| 1 | 0 | 84 | 85 | 92 |
| 2 | 0 | 82 | 86 | 90 |
| 3 | 0 | 83 | 83 | 91 |
| 4 | 2 | 62 | 67 | 63 |
| 5 | 3 | 64 | 66 | 65 |
| 6 | 2 | 63 | 65 | 62 |
| 7 | 1 | 81 | 82 | 86 |
| 8 | 0 | 68 | 71 | 69 |
From above proof test data, 1-3 group have employed the delay aging drug compositions that present composition raw material composition prepares with formula, there is synergistic function, the highest to the suppression ratio of TYR enzyme, superoxide anion clearance, hydroxy radical ion remaval rate, anti-aging effects is notable, and drug effect is gentle, has no side effect, the allergy rate of skin is the lowest, is suitable for various people and uses；4-5 group is each employs raw-material one in inventive formulation less, and compositions loses synergistic function, and anti-aging effects is poor, has a small amount of side effect, and skin allergy rate is higher；The 6th group of raw material number not using the present composition, the compositions prepared loses synergistic function, and anti-aging effects is poor, has a small amount of side effect, and skin allergy rate is higher；The 7th group of method not using the present invention to prepare compositions, has preferable anti-aging effects equally, higher to the allergy rate of skin；8th group is situation after existing anti-aging cosmetics uses, and its anti-aging effects is general, and skin allergy rate is low.
Claims (10)
1. the delay aging drug compositions for cosmetics containing Radix Scrophulariae, it is characterized in that, described compositions is to be prepared from by the raw material of following weight: Spica Prunellae 15-20 part, Radix Scrophulariae 10-20 part, Radix Glycyrrhizae 12-18 part, Passiflora edulis sims 20-30 part, Rhizoma Curcumae Longae 5-10 part, Rhizoma Imperatae 5-10 part, Caulis fici pumilae (Fructus Fici Pumilae) 10-15 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Spica Prunellae 18-20 part, Radix Scrophulariae 10-15 part, Radix Glycyrrhizae 12-15 part, Passiflora edulis sims 25-30 part, Rhizoma Curcumae Longae 8-10 part, Rhizoma Imperatae 5-8 part, Caulis fici pumilae (Fructus Fici Pumilae) 12-15 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Spica Prunellae 18 parts, Radix Scrophulariae 15 parts, 13 parts of Radix Glycyrrhizae, Passiflora edulis sims 28 parts, 9 parts of Rhizoma Curcumae Longae, Rhizoma Imperatae 6 parts, Caulis fici pumilae (Fructus Fici Pumilae) 14 parts.
4., according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, concrete preparation process is as follows:
1), by Spica Prunellae, Radix Scrophulariae, Radix Glycyrrhizae, Passiflora edulis sims, Rhizoma Curcumae Longae, Rhizoma Imperatae, Caulis fici pumilae (Fructus Fici Pumilae) is pulverized after being separately dried, and extracts with ethanol solution and concentrates, and obtains Spica Prunellae extracting solution, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution；
2), the Spica Prunellae extracting solution of step 1 gained, Radix Scrophulariae extracting solution, Radix Glycyrrhizae extract, Passiflora edulis sims extracting solution, Rhizoma Curcumae Longae extracting solution, Rhizoma Imperatae extracting solution, Caulis fici pumilae (Fructus Fici Pumilae) extracting solution are carried out maturation process respectively, mix homogeneously after cooling, and again carry out filtering, purifying, obtain mixing essence；
3) the mixing essence, by step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Spica Prunellae extracting solution is 68-70 DEG C, pressure is 0.2-0.4MPa, the time is 1-2h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Scrophulariae extracting solution is 88-93 DEG C, pressure is 0.2-0.3MPa, the time is 4-5h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Glycyrrhizae extract is 75-80 DEG C, pressure is 0.4-0.5MPa, the time is 3-4h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Passiflora edulis sims extracting solution is 65-70 DEG C, pressure is 0.1-0.2MPa, the time is 0.5-1h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Rhizoma Curcumae Longae extracting solution is 82-85 DEG C, pressure is 0.1-0.2MPa, the time is 2-3h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Rhizoma Imperatae extracting solution is 71-75 DEG C, pressure is 0.2-0.3MPa, the time is 2-3h；The curing temperature of Caulis fici pumilae (Fructus Fici Pumilae) extracting solution is 63-65 DEG C, pressure is 0.1-0.2MPa, the time is 1-2h.
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| CN113750025A (en) * | 2021-10-21 | 2021-12-07 | 上海铮信生物科技股份有限公司 | Plant composition with anti-aging effect and application of plant composition in cosmetics |
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