CN105726421A - Cosmetic anti-aging traditional Chinese medicine composition containing ganoderma lucidum - Google Patents
Cosmetic anti-aging traditional Chinese medicine composition containing ganoderma lucidum Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a cosmetic anti-aging traditional Chinese medicine composition containing ganoderma lucidum. The composition is prepared from, by weight, 15-20 parts of lithospermum officinale roots, 10-20 parts of bighead atractylodes rhizomes, 12-18 parts of liquorice roots, 12-20 parts of tabebuia impetiginosa bark, 5-10 parts of ganoderma lucidum, 5-10 parts of hovenia dulcis fruits and 10-15 parts of barbed skullcap herb. The anti-aging effect of the composition is enhanced under the synergetic enhancement effect of the raw materials; the composition is prepared from pure natural plant extracts in a compositing mode, so that the composition is mild in medicinal effect and small in side effect; besides, the composition is high in adaptability and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst..
Background technology
Along with improving constantly of people's living standard, everybody also begins to pay close attention to other aspects, the such as appearance of oneself after meeting basic clothing, food, lodging and transportion--basic necessities of life demand.Pursuit to the oldest appearance occurs the most until now in fact, from ancient times to the present, from man to female, from west to east, from Black people to white man, is the most all seeking this possibility.Along with science and technology development, it is achieved probability also gradually step up, anti-aging cosmetics is the most increasingly paid close attention to by people.
Skin is the most all aging, and its elasticity slowly reduces, and thin down, more and more fragile and lax, be wrinkled exactly to the visual impression of people.According to the Aging Mechanism of skin, the approach of defying age can be inquired into.Sum up and specifically include that protecting the skin from external environment stimulates；Unnecessary free radical in scavenger cell；Skin Cell is repaired and supplements the nutrients.Skin anti-aging is to prevent skin from occurring the function of gradually property and organic moving back to sexually revise because of time passage, shows as preventing wrinkle, dry, a bits, lax and mottle.Anti-aging cosmetics is exactly the cosmetics realizing senile-resistant efficacy, is one of important effect type cosmetics.
Anti-aging cosmetics substantially can be divided three classes by its function or effect difference, respectively humidity-preserving type cosmetic, anti-oxidative cosmetics and biological activity cosmetics.Activated feedstock in variety classes cosmetics is different, the most perfect along with what bioactive ingredients was studied, the kind of activated feedstock is more and more abundanter, and the activated feedstock being applied in anti-aging cosmetics is more and more numerous and diverse, but the application of the most numerous and diverse activated feedstock, make cosmetic composition more complicated, various side reactions are difficult to control to and detect, and cause cosmetics side effect to increase, worse to the adaptability of different skin quality skins, and cost is high, and anti-aging effects is poor.Therefore, invention one has that anti-aging effects is good, side effect is little, and the Chinese medicine composition of wide adaptability is to the development of cosmetic industry and to improve the living standard of people the most significant.
Summary of the invention
It is an object of the invention to overcome the deficiency that anti-aging effects is poor, side effect is big in the presence of prior art, it is provided that a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst..Said composition, by the chemiluminescence between raw material, adds the anti-aging effects of compositions, and drug effect is gentle, pure natural plant extract combines, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., said composition is to be prepared from by the raw material of following weight: Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Glycyrrhizae 12-18 part, variegated leaf roble bark 12-20 part, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 5-10 part, north trifoliate orange fruit 5-10 part, Herba Scutellariae Barbatae 10-15 part.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., wherein said Semen Ginkgo Radix Arnebiae (Radix Lithospermi), blood circulation promoting and blood stasis dispelling, except wind pain relieving, antiinflammatory.Treating rheumatic arthritis, bone fracture and injury, invigorate blood circulation, removing heat from blood, relieving constipation, measles, all diseases such as scarlet fever.
The wherein said Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI；Dampness diuretic；Hidroschesis；Antiabortive.Main deficiency-weakness of spleen-QI；Spiritlessness and weakness；The few abdominal distention of lack of appetite；Big loose stool is thin；Fluid-retention stagnating in the interior；Dysuria；Edema；Dizziness due to fluid-retention；Temperature numbness is ached；Spontaneous sweating due to deficiency of QI；Frequent fetal movement.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Wherein said Radix Glycyrrhizae, property is flat, and sweet in the mouth returns 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Wherein said variegated leaf roble bark, containing naphthoic acid (lapachol), Herba Alii fistulosi quinone, coumarin, flavone, the dilute ether of ring and Carnosol.There is antibacterial, antifungal, immune activation, antiinflammatory, toxin expelling, nourishing and antitumor action.
Wherein said Ganoderma lucidum (Leyss. Ex Fr.) Karst., bitter in the mouth, property is put down.Solve breast stomach pent-up, invigorating the spleen and replenishing QI, make people have a clear mind.Containing active polysaccharide, Ganoderma polypeptide, triterpenes, 16 kinds of aminoacid (wherein containing seven kinds of essential amino acids), protein, steroid, mannitol, coumarin glycosides, alkaloid, organic acid (main containing Fumaric acid), and trace element Ge, P, Fe, Ca, Mn, Zn, etc. active ingredient, can symptomatic treatment cardiovascular and cerebrovascular vessel, digestion, nerve, endocrine, breathe, each systemic disease such as motion, especially the most notable to the preventive and therapeutic effect of tumor, hepatic lesions, antiinflammatory, insomnia and aging.
Wherein said northern trifoliate orange fruit, sweet in the mouth, property is put down.Promoting flow of QI and blood, for viscerasthenia hemoptysis, bones and muscles pain due to rheumatism, has heat clearing away, only excessive thirst, invigorating the spleen and replenishing QI, moistening five ZANG-organs, effect of relaxing muscles and tendons network.Control drunk, dysphoria with smothery sensation, thirsty, vomiting, difficulty in urination and defecation.
Wherein said Herba Scutellariae Barbatae, acrid in the mouth, property is put down.Return lung, liver, kidney channel, have heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, anticancer effect；Appendicitis curing, hepatitis, stomachache, early hepatocarcinoma, pulmonary carcinoma, cervical cancer, mastitis etc.；The diseases such as external is controlled pain furuncle and treated, treating swelling and pain by traumatic injury.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., preferably, said composition is to be prepared from by the raw material of following weight: Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15-18 part, Rhizoma Atractylodis Macrocephalae 10-12 part, Radix Glycyrrhizae 12-15 part, variegated leaf roble bark 15-18 part, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 5-8 part, north trifoliate orange fruit 8-10 part, Herba Scutellariae Barbatae 10-12 part；It is further preferred that said composition is to be prepared from by the raw material of following weight: Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, 12 parts of Radix Glycyrrhizae, 16 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 8 parts, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts.Preferably can make the synergistic function maximum of compositions by above-mentioned, anti-aging effects reaches optimal, and side effect is minimum.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., in addition to above-mentioned necessary raw material, also can add auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water etc. according to actual needs.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., can make cosmetics with conventional base material by arbitrary proportion, and State of cosmetics can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., said composition is made up of the natural material of multiple gentleness, synergistic function by active component different in each raw material, excite the activity of activity of fighting against senium material therein the most greatly, and drug effect is gentle, have no side effect, be suitable for all kinds of skin quality, skin is high to the absorption efficiency of defying age active matter, and anti-aging effects is notable.
Further, the invention provides the preparation method of a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., its concrete preparation process is as follows:
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst., north trifoliate orange fruit, Herba Scutellariae Barbatae is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution are carried out maturation process respectively, mix homogeneously after cooling, and again carry out filtering, purifying, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age.
The preparation method of above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., wherein to Semen Ginkgo Radix Arnebiae (Radix Lithospermi) in step 1, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst., north trifoliate orange fruit, the extraction of Herba Scutellariae Barbatae, method for concentration are conventional plant extract, method for concentration, can be separated by the active ingredient of the defying age in plant, and increase activity component concentration, improve anti-aging effects.
The preparation method of above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., wherein to Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution in step 2, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution carries out maturation process respectively, i.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in plant, reduce side effect, improve the adaptability to different skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin.
Wherein, in described curing process, the cooking conditions to each raw material is different, can be under conditions of the activity farthest ensureing activity of fighting against senium composition, destroy the easy allergin in plant, reduce side effect, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin, its temperature, pressure and time specifically chosen as follows:
The preparation method of above-mentioned a kind of delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., by to the ripening at different conditions of different material extracting solution, easy allergin in raw material extracting solution is inactivated or decomposes, and retain the active component of the defying age of energy Synergistic, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only reduce the allergy probability of Chinese medicine composition, improve adaptability, can also improve the absorption efficiency of skin, anti-aging effects is more preferable.
Compared with prior art, beneficial effects of the present invention:
1, the present composition is by the synergistic function of active component different in each raw material, excites the activity of activity of fighting against senium material therein greatly, and anti-aging effects is good.
2, the present composition selects multiple gentle preparation of raw material to form, and drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, more preferable to the permeability of skin, is easily absorbed by the skin, improves anti-aging effects.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easy anaphylaxis and side reaction, improves the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should not being interpreted as, the scope of the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to the scope of the present invention.
Embodiment 1
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, 12 parts of Radix Glycyrrhizae, 16 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 8 parts, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence；By the Rhizoma Atractylodis Macrocephalae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Atractylodis Macrocephalae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the variegated leaf roble bark extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain variegated leaf roble bark essence；By the Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution of step 1 gained at 88 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence；By the northern trifoliate orange fruit extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain northern trifoliate orange fruit essence；By the Herba Scutellariae Barbatae extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 0.5h under 0.1MPa pressure filtering, purifying, cool down to obtain Herba Scutellariae Barbatae essence；By the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence of gained, Rhizoma Atractylodis Macrocephalae essence, Radix Glycyrrhizae essence, variegated leaf roble bark essence, Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence, north trifoliate orange fruit essence, Herba Scutellariae Barbatae essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
It is good that this cosmetic emulsion has anti-aging effects, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 2
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 18 parts of Radix Glycyrrhizae, 12 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 5 parts, north trifoliate orange fruit 10 parts, Herba Scutellariae Barbatae 15 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 2h under 0.1MPa pressure filtering, purifying, cool down to obtain Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence；By the Rhizoma Atractylodis Macrocephalae extracting solution of step 1 gained at 73 DEG C, carry out after carrying out ripening 3h under 0.3MPa pressure filtering, purifying, cool down to obtain Rhizoma Atractylodis Macrocephalae essence；By the Radix Glycyrrhizae extract of step 1 gained at 75 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the variegated leaf roble bark extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain variegated leaf roble bark essence；By the Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution of step 1 gained at 90 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence；By the northern trifoliate orange fruit extracting solution of step 1 gained at 71 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain northern trifoliate orange fruit essence；By the Herba Scutellariae Barbatae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Herba Scutellariae Barbatae essence；By the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence of gained, Rhizoma Atractylodis Macrocephalae essence, Radix Glycyrrhizae essence, variegated leaf roble bark essence, Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence, north trifoliate orange fruit essence, Herba Scutellariae Barbatae essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
It is good that this cosmetic emulsion has anti-aging effects, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 3
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 20 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 12 parts of Radix Glycyrrhizae, 20 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 10 parts, north trifoliate orange fruit 10 parts, Herba Scutellariae Barbatae 10 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 2h under 0.2MPa pressure filtering, purifying, cool down to obtain Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence；By the Rhizoma Atractylodis Macrocephalae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Atractylodis Macrocephalae essence；By the Radix Glycyrrhizae extract of step 1 gained at 80 DEG C, carry out after carrying out ripening 4h under 0.4MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the variegated leaf roble bark extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain variegated leaf roble bark essence；By the Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution of step 1 gained at 85 DEG C, carry out after carrying out ripening 2h under 0.3MPa pressure filtering, purifying, cool down to obtain Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence；By the northern trifoliate orange fruit extracting solution of step 1 gained at 71 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain northern trifoliate orange fruit essence；By the Herba Scutellariae Barbatae extracting solution of step 1 gained at 63 DEG C, carry out after carrying out ripening 0.5h under 0.2MPa pressure filtering, purifying, cool down to obtain Herba Scutellariae Barbatae essence；By the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence of gained, Rhizoma Atractylodis Macrocephalae essence, Radix Glycyrrhizae essence, variegated leaf roble bark essence, Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence, north trifoliate orange fruit essence, Herba Scutellariae Barbatae essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
It is good that this cosmetic emulsion has anti-aging effects, has no side effect, the advantage of suitable various skin skin quality.
Comparative example 1
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, 12 parts of Radix Glycyrrhizae, 16 parts of variegated leaf roble bark, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts is pulverized after being separately dried, and extracts with ethanol solution and concentrates, and obtains Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence；By the Rhizoma Atractylodis Macrocephalae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Atractylodis Macrocephalae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the variegated leaf roble bark extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain variegated leaf roble bark essence；By the northern trifoliate orange fruit extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain northern trifoliate orange fruit essence；By the Herba Scutellariae Barbatae extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 0.5h under 0.1MPa pressure filtering, purifying, cool down to obtain Herba Scutellariae Barbatae essence；By the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence of gained, Rhizoma Atractylodis Macrocephalae essence, Radix Glycyrrhizae essence, variegated leaf roble bark essence, north trifoliate orange fruit essence, Herba Scutellariae Barbatae essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
Comparative example 2
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, 16 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 8 parts, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts is pulverized after being separately dried, and extracts with ethanol solution and concentrates, and obtains Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence；By the Rhizoma Atractylodis Macrocephalae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Atractylodis Macrocephalae essence；By the variegated leaf roble bark extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain variegated leaf roble bark essence；By the Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution of step 1 gained at 88 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence；By the northern trifoliate orange fruit extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain northern trifoliate orange fruit essence；By the Herba Scutellariae Barbatae extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 0.5h under 0.1MPa pressure filtering, purifying, cool down to obtain Herba Scutellariae Barbatae essence；By the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence of gained, Rhizoma Atractylodis Macrocephalae essence, variegated leaf roble bark essence, Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence, north trifoliate orange fruit essence, Herba Scutellariae Barbatae essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
Comparative example 3
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 25 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, 12 parts of Radix Glycyrrhizae, 10 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 18 parts, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.1MPa pressure filtering, purifying, cool down to obtain Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence；By the Rhizoma Atractylodis Macrocephalae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Rhizoma Atractylodis Macrocephalae essence；By the Radix Glycyrrhizae extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 4h under 0.5MPa pressure filtering, purifying, cool down to obtain Radix Glycyrrhizae essence；By the variegated leaf roble bark extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 4h under 0.2MPa pressure filtering, purifying, cool down to obtain variegated leaf roble bark essence；By the Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution of step 1 gained at 88 DEG C, carry out after carrying out ripening 3h under 0.2MPa pressure filtering, purifying, cool down to obtain Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence；By the northern trifoliate orange fruit extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 1h under 0.2MPa pressure filtering, purifying, cool down to obtain northern trifoliate orange fruit essence；By the Herba Scutellariae Barbatae extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 0.5h under 0.1MPa pressure filtering, purifying, cool down to obtain Herba Scutellariae Barbatae essence；By the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) essence of gained, Rhizoma Atractylodis Macrocephalae essence, Radix Glycyrrhizae essence, variegated leaf roble bark essence, Ganoderma lucidum (Leyss. Ex Fr.) Karst. essence, north trifoliate orange fruit essence, Herba Scutellariae Barbatae essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
Comparative example 4
1, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, 12 parts of Radix Glycyrrhizae, 16 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 8 parts, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2, by Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age；
4, take delay aging drug compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make anti-aging cosmetics emulsion.
The anti-aging cosmetics that above-described embodiment 1-3 and comparative example 1-4 obtain is tried out, randomly choose 800 volunteers, it is divided into 8 groups, wherein 1-7 uses the cosmetics that embodiment and comparative example prepare respectively, select the anti-aging cosmetics that commercial type is best for 8th group, after using 15 days, skin detected and contrast, obtaining data below:
| Test group | Allergy number | TYR enzyme inhibition rate (%) | Superoxide anion clearance (%) | Hydroxy radical ion remaval rate (%) |
| 1 | 0 | 86 | 89 | 93 |
| 2 | 0 | 87 | 86 | 92 |
| 3 | 0 | 85 | 87 | 91 |
| 4 | 2 | 66 | 63 | 68 |
| 5 | 3 | 64 | 66 | 70 |
| 6 | 2 | 63 | 65 | 71 |
| 7 | 1 | 82 | 78 | 85 |
| 8 | 0 | 72 | 69 | 75 |
From above proof test data, 1-3 group have employed the delay aging drug compositions that present composition raw material composition prepares with formula, there is synergistic function, the highest to the suppression ratio of TYR enzyme, superoxide anion clearance, hydroxy radical ion remaval rate, anti-aging effects is notable, and drug effect is gentle, has no side effect, the allergy rate of skin is the lowest, is suitable for various people and uses；4-5 group is each employs raw-material one in inventive formulation less, and compositions loses synergistic function, and anti-aging effects is poor, has a small amount of side effect, and skin allergy rate is higher；The 6th group of raw material number not using the present composition, the compositions prepared loses synergistic function, and anti-aging effects is poor, has a small amount of side effect, and skin allergy rate is higher；The 7th group of method not using the present invention to prepare compositions, has preferable anti-aging effects equally, but higher to the allergy rate of skin；8th group is situation after existing anti-aging cosmetics uses, and its anti-aging effects is general, and skin allergy rate is low.
Claims (10)
1. the delay aging drug compositions for cosmetics containing Ganoderma lucidum (Leyss. Ex Fr.) Karst., it is characterized in that, described compositions is to be prepared from by the raw material of following weight: Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Glycyrrhizae 12-18 part, variegated leaf roble bark 12-20 part, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 5-10 part, north trifoliate orange fruit 5-10 part, Herba Scutellariae Barbatae 10-15 part.
Chinese medicine composition the most according to claim 1, it is characterized in that, described compositions is to be prepared from by the raw material of following weight: Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15-18 part, Rhizoma Atractylodis Macrocephalae 10-12 part, Radix Glycyrrhizae 12-15 part, variegated leaf roble bark 15-18 part, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 5-8 part, north trifoliate orange fruit 8-10 part, Herba Scutellariae Barbatae 10-12 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Semen Ginkgo Radix Arnebiae (Radix Lithospermi) 15 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, 12 parts of Radix Glycyrrhizae, 16 parts of variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 8 parts, north trifoliate orange fruit 9 parts, Herba Scutellariae Barbatae 12 parts.
4., according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, concrete preparation process is as follows:
1), by Semen Ginkgo Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, variegated leaf roble bark, Ganoderma lucidum (Leyss. Ex Fr.) Karst., north trifoliate orange fruit, Herba Scutellariae Barbatae is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution；
2), the Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution of step 1 gained, Rhizoma Atractylodis Macrocephalae extracting solution, Radix Glycyrrhizae extract, variegated leaf roble bark extracting solution, Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution, north trifoliate orange fruit extracting solution, Herba Scutellariae Barbatae extracting solution are carried out maturation process respectively, mix homogeneously after cooling, and again carry out filtering, purifying, obtain mixing essence；
3) the mixing essence, by step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for defying age.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Semen Ginkgo Radix Arnebiae (Radix Lithospermi) extracting solution is 68-72 DEG C, pressure is 0.1-0.2MPa, the time is 1-2h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Rhizoma Atractylodis Macrocephalae extracting solution is 70-73 DEG C, pressure is 0.2-0.3MPa, the time is 2-3h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Glycyrrhizae extract is 75-80 DEG C, pressure is 0.4-0.5MPa, the time is 3-4h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of variegated leaf roble bark extracting solution is 65-70 DEG C, pressure is 0.2-0.3MPa, the time is 3-4h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution is 85-90 DEG C, pressure is 0.1-0.2MPa, the time is 2-3h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of north trifoliate orange fruit extracting solution is 71-73 DEG C, pressure is 0.1-0.2MPa, the time is 1-2h；The curing temperature of Herba Scutellariae Barbatae extracting solution is 63-68 DEG C, pressure is 0.1-0.2MPa, the time is 0.5-1h.
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