CN105687062A - Whitening traditional Chinese medicine composition containing dictyophora indusiata for cosmetics - Google Patents
Whitening traditional Chinese medicine composition containing dictyophora indusiata for cosmetics Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention discloses a whitening traditional Chinese medicine composition containing dictyophora indusiata for cosmetics.The composition is prepared from, by weight, 10-15 parts of selfheal, 8-12 parts of dictyophora indusiata, 12-16 parts of evening primrose, 6-10 parts of radix scutellariae, 10-15 parts of licorice roots and 6-9 parts of nephelium lappaceum.The whitening effect of the composition is enhanced through the synergistic enhancing effect of the raw materials, the medicine effect is mild, and the composition is composed of pure natural plant extracts and is small in side effect, wide in application range and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora。
Background technology
China, from ancient times with Bai Weimei, as the saying goes " a white screening hundred is ugly ", and lifetime that whitening skin is many Mies pursues。Recently as expanding economy and growth in the living standard, people increasingly pay attention to the natural whitening of skin, this is just for suppressing the black pigment of skin synthesis, and then the various American and Japanese firms reaching skin whitening effects provide wide application prospect, make the demand of this kind of cosmetics in continuing ascendant trend。
In normal state, the color of human skin depends on melanic content and distribution, so the core content of lightening mechanism suppresses melanic formation exactly and accelerates melanic decomposition。The physiological process that melanin is formed and discharges is summarised as substantially: melanocyte produces melanin；Melanin granule is shifted to horn cell by melanocyte dendritic processes；The melanin granule of angle of shift cell plastid goes upward to horny layer with epidermis cell, and comes off along with horny layer and drain。
In recent years, the whitening agent used in cosmetics mainly has the compounds such as hydroquinone (hydroquinone), L-AA (vitamin C), kojic acid, superoxide dismutase (SOD) and arbutin。But these whitening agents also exist many defects, zest such as hydroquinone is very big, vitamin C and SOD are highly unstable, kojic acid also has certain zest and property easy to change, arbutin effect is single and poor effect, the permeability adding active matter is undesirable, the effect making these whitening products is poor, and these substantial amounts of whitening agents remain in the zest and anaphylaxis that can cause again skin on skin, consumer's effect demand to whitening product can not be met, so exploitation has good safety, stability, inhibition is obvious, the natural whiting agent that cost performance is good, become one of main direction of studying of current medicine and cosmetic industry, there is extraordinary development prospect。
Summary of the invention
It is an object of the invention to overcome the deficiency that whitening effect is poor, side effect is big existing in prior art, it is provided that a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora。Said composition, by the chemiluminescence between raw material, adds the whitening effect of compositions, and drug effect is gentle, pure natural plant extract combines, and side effect is little, and wide adaptability is with low cost。
In order to realize foregoing invention purpose, the invention provides a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, said composition is to be prepared from by the raw material of following weight: Spica Prunellae 10-15 part, Cultivation of Dictyophora 8-12 part, Radix Oenotherae erythrosepalae 12-16 part, Radix Scutellariae 6-10 part, Radix Glycyrrhizae 10-15 part, Fructus nephelii topengii 6-9 part。
Above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, wherein said Spica Prunellae, acrid in the mouth, hardship；Cold in nature；Return liver, gallbladder meridian；There is the effect letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis。Cure mainly lymphoid tuberculosis, goiter, acute mastitis, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, metrorrhagia, leukorrhagia, Fiedeler's disease type hepatitis and bacillary dysentery etc.。
Wherein said Cultivation of Dictyophora, sweet in the mouth, hardship；Cool in nature；There is boosting qi and nourishing yin；Nourishing the lung to arrest cough；Effect of clearing away heat-damp and promoting diuresis；Cure mainly deficiency of the lung heat syndrome cough；Laryngitis；Dysentery；Leucorrhea；Hypertension；Hyperlipemia；Tumor；Containing several amino acids, skin is had good nutrition, moistens effect。
Wherein said Radix Oenotherae erythrosepalae, sweet in the mouth, hardship；Warm in nature；There is effect of bone and muscle strengthening, expelling wind and removing dampness；For treating the diseases such as rheumatism, bones and muscles pain；Cure mainly soreness of bones and muscles, promoting blood circulation to remove obstruction in the collateral；Endogenous wind stopping suppressing the hyperactive liver；Detumescence sore。Main obstruction of qi in the chest and cardialgia；Apoplectic hemiplegia；Stirring-up of pathogenic wind in the interior resulting from deficiency；Children's moves more；Wind dampness rheumatic anesthesia pain；Stomachache is had loose bowels；Dysmenorrhea；Oral-anal-genital ulcer syndrome；Skin infection；Eczema。
Wherein said Radix Scutellariae, bitter in the mouth；Cold in nature；GUIXIN, lung, gallbladder, large intestine channel；There is removing the relative excess fire, dehumidifying heat, hemostasis, antiabortive effect；Cure mainly high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, collapse, leak, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle。
Wherein said Radix Glycyrrhizae, sweet in the mouth；Property is put down；Return spleen, stomach, lung meridian；There is QI invigorating invigorating middle warmer；Relieving spasm to stop pain；Nourishing the lung to arrest cough；Eliminating fire and detoxication；Effect of coordinating the actions of various ingredients in a prescription；Cure mainly asthenia lack of appetite；Leanness yellowish complexion；Shortness of breath and palpitation；Stomachache loose stool；Extremity contraction urgency pain；Hysteria；Cough and asthma；Laryngopharynx swelling and pain；Ulcerative carbuncle swells and ache；Infantile carbuncle；And medicine, alimentary toxicosis。For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong。
Wherein said Fructus nephelii topengii, sweet in the mouth acid, warm in nature；Return liver, stomach warp；Having the benefit blood that promotes the production of body fluid, invigorating the spleen to arrest diarrhea, warming middle-JIAO is regulated the flow of vital energy, effect of sending down the abnormal ascending QI, can strengthen body immunity, hair care skin Caring；Cure mainly the diseases such as anemia, insufficiency of the spleen chronic diarrhea, deficiency of vital energy cold syndrome of the stomach, dizziness, hypotension。
Above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, it is preferred that said composition is to be prepared from by the raw material of following weight: Spica Prunellae 11-13 part, Cultivation of Dictyophora 10-12 part, Radix Oenotherae erythrosepalae 12-14 part, Radix Scutellariae 8-10 part, Radix Glycyrrhizae 13-15 part, Fructus nephelii topengii 6-8 part；It is further preferred that said composition is to be prepared from by the raw material of following weight: Spica Prunellae 12 parts, Cultivation of Dictyophora 10 parts, Radix Oenotherae erythrosepalae 15 parts, Radix Scutellariae 9 parts, 14 parts of Radix Glycyrrhizae, Fructus nephelii topengii 7 parts。Preferably the synergistic function that can make compositions is maximum by above-mentioned, and whitening effect reaches the best, and side effect is minimum。
Above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, except above-mentioned necessary raw material, also can add auxiliary material according to actual needs, for instance, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water etc.。
Above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, can make cosmetics with conventional base material by arbitrary proportion, and State of cosmetics can be the one in solution, suspension, emulsion, paste, quintessence oil, spray。
Above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, said composition is made up of the natural material of multiple gentleness, synergistic function by active component different in each raw material, the formation of intracellular melanin be can effectively suppress and the melanic decomposition in extracellular, discharge accelerated, thus reaching quick whitening and continuing the effect of whitening, whitening effect is better, and drug effect is gentle, have no side effect, be suitable for all kinds of skin quality。
Further, the preparation method that the invention provides a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, its concrete preparation process is as follows:
1, pulverize after Spica Prunellae, Cultivation of Dictyophora, Radix Oenotherae erythrosepalae, Radix Scutellariae, Radix Glycyrrhizae, Fructus nephelii topengii being separately dried, carry out extracting and concentrating, obtain Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, the Spica Prunellae extracting solution of step 1 gained, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution are carried out maturation process respectively, it is filtered after cooling, purifies to obtain each raw material essence, by each raw material essence mix homogeneously, and be again filtered, purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora。
The preparation method of above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, wherein to Spica Prunellae in step 1, Cultivation of Dictyophora, Radix Oenotherae erythrosepalae, Radix Scutellariae, the extraction of Radix Glycyrrhizae, method for concentration are conventional plant extract, method for concentration, can be separated by the active ingredient of the defying age in plant, and increase activity component concentration, improve whitening effect。
The preparation method of above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, wherein Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract are carried out maturation process by step 2 respectively, namely plant extraction liquid is heated pressurized treatments, destroy the easy allergin in plant, reduce side effect, improve the adaptability to different skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin。
Wherein, in described curing process the cooking conditions of each raw material is different, can be formed farthest ensuring a suppression of melanin and promote under the reactive conditions of active substance of melanin decomposition, destroy the easy allergin in plant, reduce side effect, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin, its temperature, pressure and time specifically chosen as follows:
| Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
| Spica Prunellae | 65-70 | 0.1-0.2 | 0.5-1 |
| Cultivation of Dictyophora | 75-80 | 0.1-0.2 | 1-2 |
| Radix Oenotherae erythrosepalae | 60-70 | 0.1-0.2 | 0.5-1 |
| Radix Scutellariae | 80-85 | 0.1-0.2 | 1-2 |
| Radix Glycyrrhizae | 70-75 | 0.1-0.2 | 2-3 |
| Fructus nephelii topengii | 75-80 | 0.1-0.2 | 2-3 |
The preparation method of above-mentioned a kind of whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, by to the ripening at different conditions of different material extracting solution, easy allergin in raw material extracting solution is inactivated or decomposes, and the melanin that suppresses retaining energy Synergistic forms and promotes the active substance that melanin decomposes, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only reducing the allergy probability of Chinese medicine composition, improve adaptability, can also improving the absorption efficiency of skin, whitening effect is better。
Compared with prior art, beneficial effects of the present invention:
1, the present composition is by the synergistic function of active component different in each raw material, excites the activity that melanin can be suppressed to form and promote the active substance that melanin decomposes therein greatly, and whitening effect is good。
2, the present composition selects multiple gentle preparation of raw material to form, and drug effect is gentle, has no side effect。
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, and the permeability of skin is better, is very easily absorbed by the skin, improves whitening effect。
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easy anaphylaxis and side reaction, improves the adaptability of compositions。
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail。But this should not being interpreted as, the scope of the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to the scope of the present invention。
Embodiment 1
1, by Spica Prunellae 12 parts, Cultivation of Dictyophora 10 parts, Radix Oenotherae erythrosepalae 15 parts, Radix Scutellariae 9 parts, 14 parts of Radix Glycyrrhizae, Fructus nephelii topengii 7 parts is pulverized after being separately dried, and carries out extracting and concentrating with alcoholic solution, obtains Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 68 DEG C, it is filtered after carrying out ripening 0.5h under 0.1Mpa pressure, purifies, cool down to obtain Spica Prunellae essence；By the Cultivation of Dictyophora extracting solution of step 1 gained at 78 DEG C, it is filtered after carrying out ripening 2h under 0.2Mpa pressure, purifies, cool down to obtain Cultivation of Dictyophora essence；By the Radix Oenotherae erythrosepalae extracting solution of step 1 gained at 65 DEG C, it is filtered after carrying out ripening 0.5h under 0.1Mpa pressure, purifies, cool down to obtain Radix Oenotherae erythrosepalae essence；By the Radix Scutellariae extracting solution of step 1 gained at 82 DEG C, it is filtered after carrying out ripening 1h under 0.2Mpa pressure, purifies, cool down to obtain Radix Scutellariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 73 DEG C, it is filtered after carrying out ripening 3h under 0.1Mpa pressure, purifies, cool down to obtain Radix Glycyrrhizae essence；By the Fructus nephelii topengii extracting solution of step 1 gained at 78 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Fructus nephelii topengii essence；By the Spica Prunellae essence of gained, Cultivation of Dictyophora essence, Radix Oenotherae erythrosepalae essence, Radix Scutellariae essence, Radix Glycyrrhizae essence, Fructus nephelii topengii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
It is good that this cosmetic emulsion has whitening effect, has no side effect, the advantage of suitable various skin skin quality。
Embodiment 2
1, by Spica Prunellae 10 parts, Cultivation of Dictyophora 12 parts, Radix Oenotherae erythrosepalae 16 parts, Radix Scutellariae 6 parts, 10 parts of Radix Glycyrrhizae, Fructus nephelii topengii 9 parts is pulverized after being separately dried, and carries out extracting and concentrating with alcoholic solution, obtains Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 65 DEG C, it is filtered after carrying out ripening 1h under 0.1Mpa pressure, purifies, cool down to obtain Spica Prunellae essence；By the Cultivation of Dictyophora extracting solution of step 1 gained at 80 DEG C, it is filtered after carrying out ripening 1h under 0.2Mpa pressure, purifies, cool down to obtain Cultivation of Dictyophora essence；By the Radix Oenotherae erythrosepalae extracting solution of step 1 gained at 60 DEG C, it is filtered after carrying out ripening 1h under 0.1Mpa pressure, purifies, cool down to obtain Radix Oenotherae erythrosepalae essence；By the Radix Scutellariae extracting solution of step 1 gained at 80 DEG C, it is filtered after carrying out ripening 2h under 0.2Mpa pressure, purifies, cool down to obtain Radix Scutellariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 70 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Radix Glycyrrhizae essence；By the Fructus nephelii topengii extracting solution of step 1 gained at 75 DEG C, it is filtered after carrying out ripening 3h under 0.1Mpa pressure, purifies, cool down to obtain Fructus nephelii topengii essence；By the Spica Prunellae essence of gained, Cultivation of Dictyophora essence, Radix Oenotherae erythrosepalae essence, Radix Scutellariae essence, Radix Glycyrrhizae essence, Fructus nephelii topengii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
It is good that this cosmetic emulsion has whitening effect, has no side effect, the advantage of suitable various skin skin quality。
Embodiment 3
1, by Spica Prunellae 15 parts, Cultivation of Dictyophora 8 parts, Radix Oenotherae erythrosepalae 12 parts, Radix Scutellariae 6 parts, 10 parts of Radix Glycyrrhizae, Fructus nephelii topengii 6 parts is pulverized after being separately dried, and carries out extracting and concentrating with alcoholic solution, obtains Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 70 DEG C, it is filtered after carrying out ripening 1h under 0.1Mpa pressure, purifies, cool down to obtain Spica Prunellae essence；By the Cultivation of Dictyophora extracting solution of step 1 gained at 80 DEG C, it is filtered after carrying out ripening 2h under 0.2Mpa pressure, purifies, cool down to obtain Cultivation of Dictyophora essence；By the Radix Oenotherae erythrosepalae extracting solution of step 1 gained at 70 DEG C, it is filtered after carrying out ripening 1h under 0.1Mpa pressure, purifies, cool down to obtain Radix Oenotherae erythrosepalae essence；By the Radix Scutellariae extracting solution of step 1 gained at 85 DEG C, it is filtered after carrying out ripening 2h under 0.2Mpa pressure, purifies, cool down to obtain Radix Scutellariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 75 DEG C, it is filtered after carrying out ripening 3h under 0.1Mpa pressure, purifies, cool down to obtain Radix Glycyrrhizae essence；By the Fructus nephelii topengii extracting solution of step 1 gained at 80 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Fructus nephelii topengii essence；By the Spica Prunellae essence of gained, Cultivation of Dictyophora essence, Radix Oenotherae erythrosepalae essence, Radix Scutellariae essence, Radix Glycyrrhizae essence, Fructus nephelii topengii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
It is good that this cosmetic emulsion has whitening effect, has no side effect, the advantage of suitable various skin skin quality。
Comparative example 1
1, by Spica Prunellae 12 parts, Radix Oenotherae erythrosepalae 15 parts, Radix Scutellariae 9 parts, 14 parts of Radix Glycyrrhizae, Fructus nephelii topengii 7 parts is pulverized after being separately dried, and carries out extracting and concentrating with alcoholic solution, obtains Spica Prunellae extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 68 DEG C, it is filtered after carrying out ripening 0.5h under 0.1Mpa pressure, purifies, cool down to obtain Spica Prunellae essence；By the Radix Oenotherae erythrosepalae extracting solution of step 1 gained at 65 DEG C, it is filtered after carrying out ripening 0.5h under 0.1Mpa pressure, purifies, cool down to obtain Radix Oenotherae erythrosepalae essence；By the Radix Scutellariae extracting solution of step 1 gained at 82 DEG C, it is filtered after carrying out ripening 1h under 0.2Mpa pressure, purifies, cool down to obtain Radix Scutellariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 73 DEG C, it is filtered after carrying out ripening 3h under 0.1Mpa pressure, purifies, cool down to obtain Radix Glycyrrhizae essence；By the Fructus nephelii topengii extracting solution of step 1 gained at 78 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Fructus nephelii topengii essence；By the Spica Prunellae essence of gained, Radix Oenotherae erythrosepalae essence, Radix Scutellariae essence, Radix Glycyrrhizae essence, Fructus nephelii topengii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, the whitening Chinese medicament compositions for cosmetics obtained；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
Comparative example 2
1, by Spica Prunellae 12 parts, Cultivation of Dictyophora 10 parts, Radix Oenotherae erythrosepalae 15 parts, Radix Scutellariae 9 parts, Fructus nephelii topengii 7 parts is pulverized after being separately dried, and carries out extracting and concentrating with alcoholic solution, obtains Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 68 DEG C, it is filtered after carrying out ripening 0.5h under 0.1Mpa pressure, purifies, cool down to obtain Spica Prunellae essence；By the Cultivation of Dictyophora extracting solution of step 1 gained at 78 DEG C, it is filtered after carrying out ripening 2h under 0.2Mpa pressure, purifies, cool down to obtain Cultivation of Dictyophora essence；By the Radix Oenotherae erythrosepalae extracting solution of step 1 gained at 65 DEG C, it is filtered after carrying out ripening 0.5h under 0.1Mpa pressure, purifies, cool down to obtain Radix Oenotherae erythrosepalae essence；By the Radix Scutellariae extracting solution of step 1 gained at 82 DEG C, it is filtered after carrying out ripening 1h under 0.2Mpa pressure, purifies, cool down to obtain Radix Scutellariae essence；By the Fructus nephelii topengii extracting solution of step 1 gained at 78 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Fructus nephelii topengii essence；By the Spica Prunellae essence of gained, Cultivation of Dictyophora essence, Radix Oenotherae erythrosepalae essence, Radix Scutellariae essence, Fructus nephelii topengii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
Comparative example 3
1, by Spica Prunellae 20 parts, Cultivation of Dictyophora 15 parts, Radix Oenotherae erythrosepalae 10 parts, Radix Scutellariae 5 parts, 10 parts of Radix Glycyrrhizae, 5 parts of crushed after being dried of Fructus nephelii topengii, carry out extracting and concentrating with alcoholic solution, obtain Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained at 73 DEG C, it is filtered after carrying out ripening 1h under 0.1Mpa pressure, purifies, cool down to obtain Spica Prunellae essence；By the Cultivation of Dictyophora extracting solution of step 1 gained at 68 DEG C, it is filtered after carrying out ripening 1h under 0.2Mpa pressure, purifies, cool down to obtain Cultivation of Dictyophora essence；By the Radix Oenotherae erythrosepalae extracting solution of step 1 gained at 78 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Radix Oenotherae erythrosepalae essence；By the Radix Scutellariae extracting solution of step 1 gained at 88 DEG C, it is filtered after carrying out ripening 3h under 0.2Mpa pressure, purifies, cool down to obtain Radix Scutellariae essence；By the Radix Glycyrrhizae extract of step 1 gained at 72 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Radix Glycyrrhizae essence；By the Fructus nephelii topengii extracting solution of step 1 gained at 72 DEG C, it is filtered after carrying out ripening 2h under 0.1Mpa pressure, purifies, cool down to obtain Fructus nephelii topengii essence；By the Spica Prunellae essence of gained, Cultivation of Dictyophora essence, Radix Oenotherae erythrosepalae essence, Radix Scutellariae essence, Radix Glycyrrhizae essence, Fructus nephelii topengii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
Comparative example 4
1, by Spica Prunellae 12 parts, Cultivation of Dictyophora 10 parts, Radix Oenotherae erythrosepalae 15 parts, Radix Scutellariae 9 parts, 14 parts of Radix Glycyrrhizae, Fructus nephelii topengii 7 parts is pulverized after being separately dried, and carries out extracting and concentrating with alcoholic solution, obtains Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
2, by the Spica Prunellae extracting solution of step 1 gained, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora；
4, take respectively whitening Chinese medicament compositions that percentage by weight is 10%, 15% glycerol, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion。
The skin-lightening cosmetic that above-described embodiment 1-3 and comparative example 1-4 obtains is tried out, randomly choose 800 volunteers, it is divided into 8 groups, wherein 1-7 uses the cosmetics that embodiment and comparative example prepare respectively, select the skin-lightening cosmetic that commercial type is best for 8th group, after using 15 days, skin detected and contrast, obtaining data below:
| Test group | Allergy number | TYR inhibition of enzyme activity rate (%) | Melanin reduction rate (%) |
| 1 | 0 | 72 | 11.6 |
| 2 | 0 | 71 | 11.3 |
| 3 | 0 | 71 | 10.8 |
| 4 | 2 | 53 | 7.1 |
| 5 | 2 | 54 | 7.2 |
| 6 | 1 | 56 | 6.9 |
| 7 | 0 | 65 | 9.8 |
| 8 | 0 | 62 | 8.9 |
From above proof test data, 1-3 group have employed the whitening Chinese medicament compositions that present composition raw material composition prepares with formula, there is synergistic function, the maximum inhibition of TYR enzyme, melanin reduction rate is all significantly high, whitening effect is notable, and drug effect is gentle, has no side effect, the allergy rate of skin is very low, it is suitable for various people and uses；4-5 group is each employs raw-material one in inventive formulation less, and compositions loses synergistic function, and whitening effect is poor, has a small amount of side effect, and skin allergy rate is higher；The 6th group of raw material number not using the present composition, the compositions prepared loses synergistic function, and whitening effect is poor, has a small amount of side effect, and skin allergy rate is higher；The 7th group of method not using the present invention to prepare compositions, has good whitening effect equally, and the allergy rate of skin is very low；8th group is situation after existing skin-lightening cosmetic uses, and its whitening effect is general, and skin allergy rate is low。
Claims (10)
1. the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora, it is characterized in that, described compositions is to be prepared from by the raw material of following weight: Spica Prunellae 10-15 part, Cultivation of Dictyophora 8-12 part, Radix Oenotherae erythrosepalae 12-16 part, Radix Scutellariae 6-10 part, Radix Glycyrrhizae 10-15 part, Fructus nephelii topengii 6-9 part。
2. Chinese medicine composition according to claim 1, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Spica Prunellae 11-13 part, Cultivation of Dictyophora 10-12 part, Radix Oenotherae erythrosepalae 12-14 part, Radix Scutellariae 8-10 part, Radix Glycyrrhizae 13-15 part, Fructus nephelii topengii 6-8 part。
3. Chinese medicine composition according to claim 2, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Spica Prunellae 12 parts, Cultivation of Dictyophora 10 parts, Radix Oenotherae erythrosepalae 15 parts, Radix Scutellariae 9 parts, 14 parts of Radix Glycyrrhizae, Fructus nephelii topengii 7 parts。
4. Chinese medicine composition according to any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, its concrete preparation process is as follows:
(1) pulverize after, Spica Prunellae, Cultivation of Dictyophora, Radix Oenotherae erythrosepalae, Radix Scutellariae, Radix Glycyrrhizae, Fructus nephelii topengii being separately dried, carry out extracting and concentrating, obtain Spica Prunellae extracting solution, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution；
(2), the Spica Prunellae extracting solution of step 1 gained, Cultivation of Dictyophora extracting solution, Radix Oenotherae erythrosepalae extracting solution, Radix Scutellariae extracting solution, Radix Glycyrrhizae extract, Fructus nephelii topengii extracting solution are carried out maturation process respectively, it is filtered after cooling, purifies to obtain each raw material essence, by each raw material essence mix homogeneously, and be again filtered, purify, obtain mixing essence；
(3) the mixing essence, by step 2 obtained carries out homogenizing, obtains the whitening Chinese medicament compositions for cosmetics containing Cultivation of Dictyophora。
5. Chinese medicine composition according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Spica Prunellae extracting solution is 60-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h。
6. Chinese medicine composition according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Cultivation of Dictyophora extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h。
7. Chinese medicine composition according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Oenotherae erythrosepalae extract is 60-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h。
8. Chinese medicine composition according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Scutellariae extracting solution is 80-85 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h。
9. Chinese medicine composition according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Glycyrrhizae extract is 70-75 DEG C, pressure is 0.1-0.2Mpa, the time is 2-3h。
10. Chinese medicine composition according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Fructus nephelii topengii extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 2-3h。
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| CN109528613A (en) * | 2019-01-18 | 2019-03-29 | 广州市普高管理咨询有限公司 | Moisten white cosmetic composition, the white skin lightening Essence of profit and its preparation method and application |
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| CN106262798A (en) * | 2016-10-10 | 2017-01-04 | 贵州高山生物科技有限公司 | Dictyophora rubrovalvata volva dry powder and preparation method and application |
| CN109528613A (en) * | 2019-01-18 | 2019-03-29 | 广州市普高管理咨询有限公司 | Moisten white cosmetic composition, the white skin lightening Essence of profit and its preparation method and application |
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