CN105963504A - Traditional Chinese medicine hot medicated compress bag for treating hyperplasia of mammary glands and preparation method thereof - Google Patents
Traditional Chinese medicine hot medicated compress bag for treating hyperplasia of mammary glands and preparation method thereof Download PDFInfo
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- CN105963504A CN105963504A CN201610568003.4A CN201610568003A CN105963504A CN 105963504 A CN105963504 A CN 105963504A CN 201610568003 A CN201610568003 A CN 201610568003A CN 105963504 A CN105963504 A CN 105963504A
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Classifications
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Abstract
The invention relates to a traditional Chinese medicine hot medicated compress bag for treating hyperplasia of mammary glands, which comprises a main bag filled with main medicines, wherein the main bag comprises a bag body which is made of a waterproof fabric and has an opening side, and the opening side is sealed by a non-woven fabric of which the thickness is 1-5mm; the bag body of the main bag is filled with a first content and a liquid medicine, wherein the first content is mainly prepared from iron chips, schizonepeta spike, myrrh, folium artemisiae argyi, thunberg fritillary bulb, saponin and costus roots; and the liquid medicine is mainly prepared from figwort roots, bupleurum, asarum herbs, dendrobium, wedelia wallichii less, ranunculus ternatus thunb., rhizoma sparganii and mature vinegar. The hot medicated compress bag has the effects of clearing away heat and toxic materials, eliminating swelling and carbuncle as well as dissipating blood stasis and dredging collaterals, and has obvious effects on treating hyperplasia of mammary glands and mastitis.
Description
Technical field
The invention belongs to Traditional chinese medicine medicament field, particularly to a kind of Chinese medicine hot compress bag treating cyclomastopathy
And preparation method.
Background technology
Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, its pathogenic factor mainly by
Lack of proper care in endocrine hormone.Cyclomastopathy is with lump in breast, distending pain as main clinical manifestation,
Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.
This disease sickness rate the most increasingly became younger in the trend risen year by year, age in the last few years.Controlling
Doctor trained in Western medicine many employings hormone and operative treatment in treatment, need patient's life-time service hormone and chemical drugs
Thing, toxic and side effects is big, and consumption cost is high and is difficult to adhere to.Many patients are more willing to take Chinese medicine
External treatment, such as hot compress are a kind of ancient outer treating method in Chinese traditional treatment disease；Hot compress
Affected part is spread on after referring to medicine is made appropriate dosage forms heating.Outside present stage is for cyclomastopathy
Mostly being plaster with medicine, but existing patch exists DeGrain mostly, curative effect of medication is short
Technical problem.
Summary of the invention
Present invention seek to address that technical problem present in prior art.To this end, the one of the present invention
Individual purpose is to propose a kind of Chinese medicine hot compress bag treating cyclomastopathy, and this hot ironing bag has heat clearing away
Removing toxic substances, relieving swelling and disintegrating mass, the effect of dissipating blood stasis dredging collateral, treat cyclomastopathy, mastitis, have substantially
Curative effect.
Technical scheme is as follows:
A kind of Chinese medicine hot compress bag treating cyclomastopathy, including the main bag equipped with principal agent, described master
Bag includes the bag being made up and having open side of waterproof fabrics, and described open side by thickness is
The non-woven fabrics sealing of 1-5mm；The bag of described main bag is built with first content thing and liquid medicine, institute
State first content thing to be mainly prepared from by following crude drug:
Iron filings 3-12 weight portion, Herba Schizonepetae 2-6 weight portion, Myrrha 3-9 weight portion, Folium Artemisiae Argyi
1-5 weight portion, Bulbus Fritillariae Thunbergii 1-5 weight portion, Fructus Gleditsia 0.5-3 weight portion, Radix Aucklandiae 0.5-3 weight
Amount part；
Described liquid medicine is mainly prepared from by following crude drug:
Radix Scrophulariae 10-20 weight portion, Radix Bupleuri 10-20 weight portion, Herba Asari 10-20 weight portion, stone
Dry measure used in former times 5-18 weight portion, mammary gland grass 5-15 weight portion, phlegm-fire grass 5-15 weight portion, Rhizoma Sparganii 3-11
Weight portion, mature vinegar 20-45 weight portion.
Chinese medicine extraction of the present invention has thing by kinds of traditional Chinese medicines compatibility, has heat-clearing and toxic substances removing, detumescence
Burst hard, dissipating blood stasis dredging collateral effect, hyperplasia of mammary glands is had significant curative effect.
Further improve the curative effect of hot ironing bag treatment cyclomastopathy, prepare described first content thing
Also include following crude drug: Radix Glycyrrhizae 3-9 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, eupolyphaga 1-5 is heavy
Amount part, Spica Prunellae 0.5-3 weight portion, Olibanum 0.5-3 weight portion.
Further, prepare described liquid medicine and also include following crude drug: Radix Et Caulis Acanthopanacis Senticosi 5-20 is heavy
Amount part, Semen Strychni 5-15 weight portion, Ramulus Cinnamomi 5-15 weight portion, Radix Platycodonis 1-5 weight portion, river
Radix Et Rhizoma Rhei 1-5 weight portion, Radix Rhodiolae 1-5 weight portion.
In one improvement project of the present invention, described hot ironing bag also includes opening equipped with accessory drugs and with main bag
The auxiliary bag that mouth side connects, described auxiliary bag includes the bag being made up of non-woven fabrics, the bag of described auxiliary bag
Internal equipped with the second content, described second content is mainly prepared from by following raw material: remote
Infrared ceramic powder 5-20 weight portion, Actinolitum 15-30 weight portion, Pyritum 10-30 weight
Part, Testa Tritici 10-30 weight portion, Bombyx mori L. 5-20 weight portion；Described iron filings, far-infrared ceramic
The size-reduced particle diameter that is prepared as of powder, Actinolitum, Pyritum, Testa Tritici and Bombyx mori L. is 1-100 μm
Microgranule.
In a preferred composition of raw materials, described first content thing prepared by following crude drug and
Become: iron filings 8 weight portion, Herba Schizonepetae 4 weight portion, Myrrha 5 weight portion, Folium Artemisiae Argyi 3 weight portion,
Bulbus Fritillariae Thunbergii 3 weight portion, Fructus Gleditsia 1.5 weight portion, the Radix Aucklandiae 1.5 weight portion, Radix Glycyrrhizae 6.5 weight
Amount part, the Radix Angelicae Dahuricae 3 weight portion, eupolyphaga 3 weight portion, Spica Prunellae 1.5 weight portion, Olibanum 1.5
Weight portion；
Described liquid medicine is prepared from by following crude drug: Radix Scrophulariae 15 weight portion, Radix Bupleuri 15 weight
Part, Herba Asari 15 weight portion, Herba Dendrobii 12 weight portion, mammary gland grass 10 weight portions, phlegm-fire grass 12
Weight portion, Rhizoma Sparganii 7 weight portion, mature vinegar 35 weight portion, Radix Et Caulis Acanthopanacis Senticosi 12 weight portion, Semen Strychni
8 weight portions, Ramulus Cinnamomi 8 weight portion, Radix Platycodonis 3 weight portion, Radix Et Rhizoma Rhei 3 weight portion, Radix Rhodiolae
3 weight portions；
Described second content is prepared from by following crude drug: far infrared ceramic powder 10 weight
Part, Actinolitum 22 weight portion, Pyritum 20 weight portion, Testa Tritici 20 weight portion, Bombyx mori L. 15
Weight portion.
In further preferred version, described hot ironing bag also includes adjuvant, described crude drug and
The ratio of weight and number of adjuvant is 1:0.1-0.6；Described adjuvant includes main bag adjuvant, described main bag
Adjuvant includes kaolin 15-35 weight portion, carbomer 10-25 weight portion, bromination myristyl
Trimethylammonium 8-20 weight portion, sodium salicylate 3-12 weight portion.Kaolin and the interpolation of carbomer,
It is beneficial to content dispersion in liquid medicine suspend, makes content be impregnated with more abundant, improve drug effect,
Avoid content blocking non-woven fabrics to cause infiltration difficulty simultaneously；Tetradecyl trimethylammonium bromide and water
Poplar acid sodium adjuvant is used in conjunction with having good Antimicrobial preservative ability, extends the storage life of medicine.
Described adjuvant also includes that auxiliary bag adjuvant, described auxiliary bag adjuvant include peach kernel oil 20-40 weight
Part and sodium palmitate 5-30 weight portion；The common interpolation of both adjuvant, improves auxiliary further
The mobility of bag medicinal liquid, simultaneously works as lubricating moisture-keeping function.
Further in scheme, the nonwoven layer surface of described auxiliary bag is provided with tearable cover layer,
Described cover layer is polyethylene film cover.
It is a further object to provide the preparation method of a kind of above-mentioned hot ironing bag, described side
Method comprises the following steps:
(1) preparation of first content thing: weigh the iron filings of formula ratio, Herba Schizonepetae, Myrrha, Folium Artemisiae Argyi,
Bulbus Fritillariae Thunbergii, Fructus Gleditsia, the Radix Aucklandiae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, eupolyphaga, Spica Prunellae and Olibanum, grind to form
Powder, crosses 60 mesh sieves, obtains first content thing；
(2) preparation of liquid medicine:
(2.1) Radix Scrophulariae of described weight portion, Radix Bupleuri Radix Bupleuri, Rhizoma Sparganii, Radix Et Rhizoma Rhei distillation extraction are taken,
Obtain volatile oil, and collect the aqueous solution after distillation；
(2.2) Herba Asari of formula ratio, Herba Dendrobii, mammary gland grass, phlegm-fire grass, Radix Et Caulis Acanthopanacis Senticosi, Ma Qian are weighed
After son, Ramulus Cinnamomi, Radix Platycodonis, Radix Rhodiolae boiling 3 hours, add in step (2.1)
Medicinal residues after distillation, boiling twice, each 1 hour, merge decoction liquor, filter, mistake
After filter, the aqueous solution with step (2.1) merges, and is concentrated into thick shape, is cooled to room temperature, adds second
Alcohol makes alcohol content be 65%, stirring, stands 24 hours, takes supernatant and reclaims ethanol, adds
The mature vinegar of formula ratio, mix homogeneously, obtain liquid medicine；
The preparation of (3) second contents
(3.1) weigh Testa Tritici and the Bombyx mori L. of formula ratio, utilize pulverizer to pulverize, sieve, obtain big
Drug particles in 100 mesh；Testa Tritici and Bombyx mori L. granule are placed in the shearing equipped with aqueous buffer solution
Soaking 3-5h in tank, wherein, drug particles is 1:5-15 with the weight ratio of aqueous buffer solution,
Then carry out shearing-crushing and obtain micropowder suspension, after pulverizing under 30-45 DEG C of temperature conditions, profit
Being dried by drug particles suspension with vacuum drying, drug particle aggregation becomes thin film, by it
Disperse i.e. to obtain bran micropowder and Bombyx mori L. micropowder；
(3.2) weigh the Actinolitum of formula ratio, put on smokeless stove fire or in suitable container, use force
After fire heating is calcined to be popular in, pouring into soak in effect of yellow wine and effect and quench, taking-up is dried, grinding；
The Pyritum weighing formula ratio grinds, Actinolitum, Pyritum and the far infrared ceramic powder that will grind
Be prepared as the microgranule of 1500-2000 mesh with pulverizing mill, with the Testa Tritici microgranule of step (3.1) and
Bombyx mori L. microgranule mix homogeneously, obtains particulate second content；
(4) preparation of main bag: by first content thing and the liquid medicine mixing and stirring of preparation, add
The kaolin of formula ratio, carbomer, tetradecyl trimethylammonium bromide and sodium salicylate, mixing is all
After even, load in main bag and seal, the main bag of cyclomastopathy must be treated；
(5) preparation of auxiliary bag: add peach kernel oil and the palm fibre of formula ratio in the second content of preparation
Palmitic acid acid sodium, after mix homogeneously, loads in auxiliary bag and seals, must treat the auxiliary of cyclomastopathy
Bag；
(6) the main bag after step (4) being processed and the auxiliary bag after step (5) process are attached
Combination, must treat the Chinese medicine hot compress bag of cyclomastopathy.
Further, the shearing condition in described step (3) is: shearing rotating speed is
1800-2500r/m, shear time is 30-60min.
The present invention treats the Chinese medicine hot compress bag of cyclomastopathy, can be by being provided with viscous in the outside of medicated bag
Property adhesive tape, pastes hot ironing bag and is fixed on target site.Hot ironing bag, by interior transmission from one channel to another network, plays
Heat-clearing and toxic substances removing, relieving swelling and disintegrating mass, the effect of dissipating blood stasis dredging collateral, the medicine of the present invention passes through fomentation pouch-shaped
Formula has splendid curative effect for treating cyclomastopathy.Directly will additionally, this hot ironing bag changes tradition
Medicament mixed, in the preparation method of heating layer, is spaced apart by main bag and auxiliary bag, improves medicine steady
Qualitative, it is to avoid the inefficacy of oxidizable composition in some medicines, it is ensured that drug effect, and extend storage life；
In use, medicinal liquid slowly oozes out, and further increases the drug effect phase of hot ironing bag.Present invention heat
The processing preparation process pressing bag is simple, easy to use, has good market prospect.
The source of the raw material of Chinese medicine composition of the present invention:
Iron filings: the amorphous particulate of Lycoperdon polymorphum Vitt to grey black or powder.
Herba Schizonepetae: Herba Schizonepetae again, this product is labiate Herba Schizonepetae Schizonepeta
The dry aerial parts of tenuifolia Briq..
Myrrha: for olive subject plant myrrh or the gum resin of Alan fort myrrh.
Folium Artemisiae Argyi: this product is feverfew Folium Artemisiae Argyi Artemisia argyi Levl.et Vant.
Dried leaves.
Bulbus Fritillariae Thunbergii: this product is liliaceous plant Bulbus Fritillariae Thunbergii Fritillaria thunbergii Miq.
Dry bulb.
Fructus Gleditsia: pulse family mountain Fructus Gleditsia Gleditsia horrida (Thunb.) Makino [G.
Japonica Miq.], with fruit medicine.
The Radix Aucklandiae: this product is being dried of feverfew Radix Aucklandiae Aucklandia lappa Decne.
Root.
Radix Scrophulariae: this product is goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl.
Dry root.
Radix Bupleuri: for the root of samphire Radix Bupleuri, Radix Bupeuri Scorzonerfolii. etc..
Herba Asari: for aristolochiaceae plant Herba Asari or the whole herb with root of China's Herba Asari.
Herba Dendrobii: for orchid Dendrobium nobile or the stem of its multiple congener.
Mammary gland grass: Compositae Herbia Wedeliae platymiscium Folium Cannabis Herbia Wedeliae Wedelia wallichii
Less., with all herbal medicine.
Phlegm-fire grass: another name encloses JIACAO, cancer grass, QINGZHU mussel, blue or green Herba Commelinae, for Commelianaceae
The herb of plant Murdannia bracteata (C. B. Clarke) O. UhtzeexJ. K. Mortoh.
Rhizoma Sparganii: this product is Sparganiaceae plant rhizoma scirpi Sparganium stoloniferum
Buch.-Ham. dry tuber.
Radix Glycyrrhizae: for pulse family glycyrrhiza genus Radix Glycyrrhizae Glycyrrhiza uralensis Fisch.
Root and root stock.
The Radix Angelicae Dahuricae: for samphire Angelica dahurica, angelica anomala, Radix angelicae dahuricae or Yunnan cattle Radix Saposhnikoviae
Root.
Eupolyphaga: this product be Corydiidae insecticide eupolyphoge sinensis Eupolyphaga sinensis Walker or
The female worm dry body of Ji eupolyphoge sinensis Steleophaga plancyi (Boleny).
Spica Prunellae: for the fruit ear of labiate Spica Prunellae.
Olibanum: the skin zones such as olive subject plant Boswellia carterii, Bao Da Boswellia carterii, wild Boswellia carterii ooze out
Oleo-gum-resin.
Radix Et Caulis Acanthopanacis Senticosi: this product is Araliaceae Radix Et Caulis Acanthopanacis Senticosi Acanthopanax senticosus
Dry, the root and rhizome of (Rupr.et Maxim.) Harms or stem.
Semen Strychni: this product is the dry of loganiaceae plant Semen Strychni Strychnos nuxvomica L.
Dry mature seed.
Ramulus Cinnamomi: this product is being dried of canella Cortex Cinnamomi Cinnamomum cassia Presl
Twig.
Radix Platycodonis: this product is Campanulaceae Radix Platycodonis Platycodon grandiflorum (Jacq.)
A.DC. dry root.
Radix Et Rhizoma Rhei: for the rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.
Radix Rhodiolae: Crassulaceae Rhodida plant Radix Rhodiolae Rhodiola saera (Prain)
Fu, with all herbal medicine.
Actinolitum: for silicates mineral, it is that the magnesium ion more than 2% in the tremolite is by two
The mineral of valency iron ion displacement.
Far infrared ceramic powder: synthesized by inorganic mineral, nonmetal oxide and metal-oxide and forge
The white powder burnt and prepare, the present invention buys commercially available.
Pyritum: this product is sulfide-based mineral yellow iron mine race pyrite.
Testa Tritici: the seed coat under sieving after taking flour for Semen Tritici aestivi mill.
Bombyx mori L.: for the dry feces of Bombycidae animal bombyx mori larva.
Detailed description of the invention
A kind of Chinese medicine hot compress bag treating cyclomastopathy of the present invention, including the main bag equipped with principal agent,
Described main bag includes the bag being made up and having open side of waterproof fabrics, and described open side is passed through
Thickness is the non-woven fabrics sealing of 1-5mm；The bag of described main bag is built with first content thing and medicine
Water.In further improvement project, described hot ironing bag also includes opening equipped with accessory drugs and with main bag
The auxiliary bag that mouth side connects, described auxiliary bag includes the bag being made up of non-woven fabrics, the bag of described auxiliary bag
Internal equipped with the second content.
Embodiment about the concrete formula of hot ironing bag content and liquid medicine and preparation method is as follows.
Embodiment 1
The prescription of the present embodiment bag is:
Main bag:
First content thing is mainly prepared from by following crude drug: iron filings 30g, Herba Schizonepetae 20g,
Myrrha 30g, Folium Artemisiae Argyi 10g, Bulbus Fritillariae Thunbergii 10g, Fructus Gleditsia 5g, Radix Aucklandiae 5g.
Liquid medicine is mainly prepared from by following crude drug: Radix Scrophulariae 100g, Radix Bupleuri 100g, Herba Asari
100g, Herba Dendrobii 50g, mammary gland grass 50g, phlegm-fire grass 50g, Rhizoma Sparganii 30g, mature vinegar 200g.
Embodiment 2
The prescription of the present embodiment bag is:
Main bag:
First content thing is mainly prepared from by following crude drug: iron filings 120g, Herba Schizonepetae 60g,
Myrrha 90g, Folium Artemisiae Argyi 50g, Bulbus Fritillariae Thunbergii 50g, Fructus Gleditsia 30g, Radix Aucklandiae 30g.
Liquid medicine is mainly prepared from by following crude drug: Radix Scrophulariae 200g, Radix Bupleuri 200g, Herba Asari
200g, Herba Dendrobii 180g, mammary gland grass 150g, phlegm-fire grass 150g, Rhizoma Sparganii 110g, mature vinegar 450g.
Embodiment 3
The prescription of the present embodiment bag is:
Main bag:
First content thing is prepared from by following crude drug: iron filings 45g, and Herba Schizonepetae 30g does not has
Medicine 60g, Folium Artemisiae Argyi 30g, Bulbus Fritillariae Thunbergii 30g, Fructus Gleditsia 20g, Radix Aucklandiae 20g, Radix Glycyrrhizae 30g, in vain
Root of Dahurian angelica 10g, eupolyphaga 10g, Spica Prunellae 5g, Olibanum 5g.
Liquid medicine is prepared from by following crude drug: Radix Scrophulariae 150g, Radix Bupleuri 150g, Herba Asari 150g,
Herba Dendrobii 100g, mammary gland grass 100g, phlegm-fire grass 100g, Rhizoma Sparganii 60g, mature vinegar 200g, sting five
Add 50g, Semen Strychni 50g, Ramulus Cinnamomi 50g, Radix Platycodonis 10g, Radix Et Rhizoma Rhei 10g, Radix Rhodiolae 10g.
Preparation method:
(1) preparation of first content thing: weigh the iron filings of formula ratio, Herba Schizonepetae, Myrrha, Folium Artemisiae Argyi,
Bulbus Fritillariae Thunbergii, Fructus Gleditsia, the Radix Aucklandiae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, eupolyphaga, Spica Prunellae and Olibanum, grind to form
Powder, crosses 60 mesh sieves, obtains first content thing；
(2) preparation of liquid medicine:
(2.1) take the Radix Scrophulariae of described weight portion, Radix Bupleuri, Rhizoma Sparganii, Radix Et Rhizoma Rhei distillation extraction, obtain
Volatile oil, and collect the aqueous solution after distillation；
(2.2) weigh the Herba Asari of formula ratio, Herba Dendrobii, mammary gland grass, phlegm-fire grass, mature vinegar, Radix Et Caulis Acanthopanacis Senticosi,
After Semen Strychni, Ramulus Cinnamomi, Radix Platycodonis, Radix Rhodiolae boiling 3 hours, add step (2.1)
Medicinal residues after middle distillation, boiling twice, each 1 hour, merge decoction liquor, filter,
After filtration, the aqueous solution with step (2.1) merges, and is concentrated into thick shape, is cooled to room temperature, adds
Ethanol makes alcohol content be 65%, stirring, stands 24 hours, after taking supernatant recovery ethanol,
Add the mature vinegar of formula ratio, mix homogeneously, obtain liquid medicine；
(3) preparation of main bag: by first content thing and the liquid medicine mixing and stirring of preparation, load
Main bag seals, the hot ironing bag of cyclomastopathy must be treated.
Embodiment 4
The prescription of the present embodiment bag is:
Main bag:
First content thing is prepared from by following crude drug: iron filings 45g, and Herba Schizonepetae 30g does not has
Medicine 60g, Folium Artemisiae Argyi 30g, Bulbus Fritillariae Thunbergii 30g, Fructus Gleditsia 20g, Radix Aucklandiae 20g, Radix Glycyrrhizae 30g, in vain
Root of Dahurian angelica 10g, eupolyphaga 10g, Spica Prunellae 5g, Olibanum 5g.
Liquid medicine is prepared from by following crude drug: Radix Scrophulariae 150g, Radix Bupleuri 150g, Herba Asari 150g,
Herba Dendrobii 100g, mammary gland grass 100g, phlegm-fire grass 100g, Rhizoma Sparganii 60g, mature vinegar 350g, sting five
Add 50g, Semen Strychni 50g, Ramulus Cinnamomi 50g, Radix Platycodonis 10g, Radix Et Rhizoma Rhei 10g, Radix Rhodiolae 50g.
Auxiliary bag:
Second content is prepared from by following crude drug: far infrared ceramic powder 50g, Actinolitum
150g, Pyritum 100g, Testa Tritici 100g, Bombyx mori L. 50g.
Preparation method:
(1) preparation of first content thing: weigh the iron filings of formula ratio, Herba Schizonepetae, Myrrha, Folium Artemisiae Argyi,
Bulbus Fritillariae Thunbergii, Fructus Gleditsia, the Radix Aucklandiae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, eupolyphaga, Spica Prunellae and Olibanum, grind to form
Powder, crosses 60 mesh sieves, obtains first content thing；
(2) preparation of liquid medicine:
(2.1) take the Radix Scrophulariae of described weight portion, Radix Bupleuri, Rhizoma Sparganii, Radix Et Rhizoma Rhei distillation extraction, obtain
Volatile oil, and collect the aqueous solution after distillation；
(2.2) Herba Asari of formula ratio, Herba Dendrobii, mammary gland grass, phlegm-fire grass, Radix Et Caulis Acanthopanacis Senticosi, Ma Qian are weighed
After son, Ramulus Cinnamomi, Radix Platycodonis, Radix Rhodiolae boiling 3 hours, add in step (2.1)
Medicinal residues after distillation, boiling twice, each 1 hour, merge decoction liquor, filter, mistake
After filter, the aqueous solution with step (2.1) merges, and is concentrated into magma shape, is cooled to room temperature, adds
Ethanol makes alcohol content be 65%, stirring, stands 24 hours, after taking supernatant recovery ethanol,
Add the mature vinegar of formula ratio, mix homogeneously, obtain liquid medicine；
The preparation of (3) second contents
(3.1) weigh Testa Tritici and the Bombyx mori L. of formula ratio, utilize pulverizer to pulverize, sieve, obtain big
Testa Tritici and Bombyx mori L. drug particles in 100 mesh；Testa Tritici and Bombyx mori L. drug particles are placed in equipped with slow
The shearing tank of bath solution soaks 3-5h, wherein, drug particles and the weight of aqueous buffer solution
Amount ratio is 1:5-15, prepares aqueous solution；Then aqueous solution carries out shearing-crushing obtain micropowder and mix
Suspension, after pulverizing under 30-45 DEG C of temperature conditions, utilizes vacuum drying by drug particles suspendible
Liquid is dried, and drug particle aggregation becomes thin film, is disperseed, and obtains Testa Tritici microgranule and Bombyx mori L. is micro-
Grain；
(3.2) weigh the Actinolitum of formula ratio, put on smokeless stove fire or in suitable container, use force
After fire heating is calcined to be popular in, pouring into soak in effect of yellow wine and effect and quench, taking-up is dried, grinding；
The Pyritum weighing formula ratio grinds, Actinolitum, Pyritum and the far infrared ceramic powder that will grind
Be prepared as the microgranule of 1500-2000 mesh with pulverizing mill, with the Testa Tritici microgranule of step (3.1) and
Rhizoma Zingiberis microgranule mix homogeneously, obtains particulate second content；
(4) preparation of main bag: by first content thing and the liquid medicine mixing and stirring of preparation, load
Main bag seals, the main bag of cyclomastopathy must be treated；
(5) preparation of auxiliary bag: the second content of preparation is loaded in auxiliary bag and seals, to obtain final product
The auxiliary bag for the treatment of cyclomastopathy；
(6) the main bag after step (4) being processed and the auxiliary bag after step (5) process are attached
Combination, and press coverlay in the nonwoven surface of auxiliary bag, the Chinese medicine of cyclomastopathy must be treated
Hot ironing bag.
Embodiment 5
The prescription of the present embodiment bag is:
Main bag:
First content thing is prepared from by following crude drug: iron filings 80g, and Herba Schizonepetae 40g does not has
Medicine 70g, Folium Artemisiae Argyi 35g, Bulbus Fritillariae Thunbergii 25g, Fructus Gleditsia 25g, Radix Aucklandiae 25g, Radix Glycyrrhizae 90g, in vain
Root of Dahurian angelica 50g, eupolyphaga 50g, Spica Prunellae 30g, Olibanum 30g.
Liquid medicine is prepared from by following crude drug: Radix Scrophulariae 180g, Radix Bupleuri 180g, Herba Asari 180g,
Herba Dendrobii 120g, mammary gland grass 120g, phlegm-fire grass 120g, Rhizoma Sparganii 80g, mature vinegar 220g, sting five
Add 200g, Semen Strychni 150g, Ramulus Cinnamomi 150g, Radix Platycodonis 50g, Radix Et Rhizoma Rhei 50g, Radix Rhodiolae
20g。
Auxiliary bag:
Second content is prepared from by following crude drug: far infrared ceramic powder 200g, and sun rises
Stone 300g, Pyritum 300g, Testa Tritici 300g, Bombyx mori L. 200g.
Preparation method: preparation method as described in Example 4.
Embodiment 6
The prescription of the present embodiment bag is:
Medicated bag:
First content thing is prepared from by following crude drug: iron filings 80g, and Herba Schizonepetae 40g does not has
Medicine 50g, Folium Artemisiae Argyi 30g, Bulbus Fritillariae Thunbergii 30g, Fructus Gleditsia 15g, Radix Aucklandiae 15g, Radix Glycyrrhizae 65g, in vain
Root of Dahurian angelica 30g, eupolyphaga 30g, Spica Prunellae 15g, Olibanum 15g.
Liquid medicine is prepared from by following crude drug: Radix Scrophulariae 150g, Radix Bupleuri 150g, Herba Asari 150g,
Herba Dendrobii 120g, mammary gland grass 100g, phlegm-fire grass 120g, Rhizoma Sparganii 70g, mature vinegar 350g, sting five
Add 120g, Semen Strychni 80g, Ramulus Cinnamomi 80g, Radix Platycodonis 30g, Radix Et Rhizoma Rhei 30g, Radix Rhodiolae 30g.
Auxiliary bag:
Second content is prepared from by following crude drug: far infrared ceramic powder 100g, and sun rises
Stone 220g, Pyritum 200g, Testa Tritici 200g, Bombyx mori L. 150g.
Preparation method: prepare according to preparation method described in embodiment 4.
Embodiment 7
The prescription of the present embodiment bag is:
Medicated bag:
First content thing 415g described in Example 6 and liquid medicine 952g；
Adjuvant: kaolin 150g, carbomer 100g, tetradecyl trimethylammonium bromide 80g,
Sodium salicylate 30g.
Auxiliary bag:
The second content 670g described in Example 6；
Adjuvant: peach kernel oil 200g and sodium palmitate 50g.
Preparation method:
(1) first content thing, liquid medicine and second content of Example 6 preparation are standby；
(2) preparation of main bag: by first content thing and liquid medicine mixing and stirring, adds formula ratio
Kaolin, carbomer, tetradecyl trimethylammonium bromide and sodium salicylate, after mix homogeneously,
Load in main bag and seal, the main bag of cyclomastopathy must be treated；
(3) preparation of auxiliary bag: add peach kernel oil and the sodium palmitate of formula ratio in the second content,
After mix homogeneously, load in auxiliary bag and seal, the auxiliary bag of cyclomastopathy must be treated；
(4) the main bag after step (2) being processed and the auxiliary bag after step (3) process are attached
Combination, and press coverlay in the nonwoven surface of auxiliary bag, the Chinese medicine of cyclomastopathy must be treated
Hot ironing bag.
Embodiment 8
The prescription of the present embodiment bag is:
Medicated bag:
First content thing 500g described in Example 6 and liquid medicine 1033g；
Adjuvant: kaolin 350g, carbomer 250g, tetradecyl trimethylammonium bromide 200g,
Sodium salicylate 120g.
Auxiliary bag:
The second content 1167g described in Example 6；
Adjuvant: peach kernel oil 400g and sodium palmitate 300g.
Preparation method: preparation method as described in Example 7.
Embodiment 9
The prescription of the present embodiment bag is:
Medicated bag:
First content thing 667g described in Example 6 and liquid medicine 1334g；
Adjuvant: kaolin 250g, carbomer 160g, tetradecyl trimethylammonium bromide 140g,
Sodium salicylate 85g.
Auxiliary bag:
The second content 787g described in Example 6；
Adjuvant: peach kernel oil 300g and sodium palmitate 180g.
Preparation method: preparation method as described in Example 7.
Embodiment 10
The prescription of the present embodiment bag is:
Medicated bag:
First content thing 667g described in Example 6 and liquid medicine 1334g；
Adjuvant: tetradecyl trimethylammonium bromide 140g, sodium salicylate 85g.
Auxiliary bag:
The second content 787g described in Example 6；
Adjuvant: peach kernel oil 300g and sodium palmitate 180g.
Preparation method: preparation method as described in Example 7.
Embodiment 11
The prescription of the present embodiment bag is:
Medicated bag:
First content thing 667g described in Example 6 and liquid medicine 1334g；
Adjuvant: kaolin 250g, carbomer 160g.
Auxiliary bag:
The second content 787g described in Example 6；
Adjuvant: peach kernel oil 300g and sodium palmitate 180g.
Preparation method: preparation method as described in Example 7.
Embodiment 12
The prescription of the present embodiment bag is:
Medicated bag:
First content thing 667g described in Example 6 and liquid medicine 1334g；
Adjuvant: kaolin 250g, tetradecyl trimethylammonium bromide 140g, sodium salicylate 85g.
Auxiliary bag:
The second content 787g described in Example 6；
Adjuvant: peach kernel oil 300g and sodium palmitate 180g.
Preparation method: preparation method as described in Example 7.
Comparative examples
The prescription of the present embodiment bag is:
Active component is prepared from by following crude drug: iron filings 80g, Herba Schizonepetae 40g, Myrrha
50g, Folium Artemisiae Argyi 30g, Bulbus Fritillariae Thunbergii 30g, Fructus Gleditsia 15g, Radix Aucklandiae 15g, Radix Glycyrrhizae 65g, the Radix Angelicae Dahuricae
30g, eupolyphaga 30g, Spica Prunellae 15g, Olibanum 15g, Radix Scrophulariae 150g, Radix Bupleuri 150g, carefully
Pungent 150g, Herba Dendrobii 120g, mammary gland grass 100g, phlegm-fire grass 120g, Rhizoma Sparganii 70g, mature vinegar 350g,
Radix Et Caulis Acanthopanacis Senticosi 120g, Semen Strychni 80g, Ramulus Cinnamomi 80g, Radix Platycodonis 30g, Radix Et Rhizoma Rhei 30g, red scape
It 30g, far infrared ceramic powder 100g, Actinolitum 220g, Pyritum 200g, Testa Tritici 200g,
Bombyx mori L. 150g.
Preparation method:
(1) weigh the Actinolitum of formula ratio, put on smokeless stove fire or in suitable container, with high heat
After heating is calcined to be popular in, pouring into soak in effect of yellow wine and effect and quench, taking-up is dried, grinding；
The Pyritum weighing formula ratio grinds, by the Actinolitum ground, Pyritum, far infrared ceramic powder
Testa Tritici and Bombyx mori L., continue to grind, and crosses 60 mesh sieves, obtains mixture of powders；
(2) Actinolitum, Pyritum, far infrared ceramic powder, Testa Tritici and the silkworm processed except step (1)
Other crude drug boilings of husky outer and mature vinegar three times, each 1 hour, merge decoction liquor,
Filter, after filtration, be concentrated into thick shape, be cooled to room temperature, add ethanol and make alcohol content be 65%, stir
Mix, stand 24 hours, after taking supernatant recovery ethanol, add the mature vinegar of formula ratio, mixing
Uniformly, steaming and decocting concentrates, and obtains thick shape mixture；
(3) mixture of powders processed in step (1) is poured into and is made up of water proof seal plastic cement and has
The bag of non-woven fabrics hot compress side, pours the thick shape mixture of step (2) into, seals and get final product.
Test example 1 stability test
To above-described embodiment 1, embodiment 3, embodiment 6, embodiment 9-12 and to according to the facts
The sample executing example carries out temperature, humidity and infiltrative influence factor test, with the dose of main bag
For reference index 1；The taste distributed with medicated bag is for reference index 2；Hot ironing bag is placed in sponge
On, with the medicated bag dose after 1h and outward appearance for reference index 3；The results are shown in Table 1.
Table 1 is the result of the test of test specimen
Condition: temperature40℃±2DEG C, under the conditions of humidity 75 ± 5%
Table 2 absorbs the result of the test of dose for sponge
Condition: under room temperature, humidity 60% ± 10%
The above results shows, embodiment 1,3,6,9-12 is in temperature 40 DEG C ± 2 DEG C, humidity 75
Under the conditions of ± 5%, stability is all better than comparative examples, and wherein the stability of embodiment 9 is
Good.The result of comparing embodiment 9, embodiment 10 and embodiment 12 understands, and compares and individually adds
Add the common of kaolin, kaolin and carbomer and add the dispersion being more conducive to content, have preferably
Suspending effect；The result of comparing embodiment 9 and embodiment 11 understands, bromination myristyl
Trimethylammonium and the shelf-life adding effectively prolongation medicine of sodium salicylate, there is preservative efficacy.
Test example 2 pharmacological toxicity is tested
Acute toxicity testing data
1, experimental technique
Depilatory is uniformly coated with by guinea pig back spinal column both sides, makes unhairing scope about 40 squares
Centimetre.Clean depilatory returns cage to observe 24 hours, and often group Cavia porcellus loses money in a business inventive embodiments respectively
1, the hot ironing bag (hot ironing bag is made 20 square centimeters of sizes) of embodiment 6 and embodiment 9,
Another group is coated with the every twice-daily of solvent 0.8ml, continuous one week, after experiment terminates, is put to death by Cavia porcellus,
The heart, liver, kidney and depilation skin do pathological examination.
2, result
Above-mentioned three groups of medication Cavia porcellus trunks depilation district, has no that local skin has edema, hyperemia, red
Speckle, petechia and ulcer.Medication group Cavia porcellus chroma of hair, ingest, the comparison such as extremity are movable
Group no significant difference, histopathologic examination, the administration group heart, liver, kidney and depilation skin and compareing
Word compares also no significant difference.
Result is pointed out, and Chinese medicine hot compress bag of the present invention, without local irritant effect, also has no general toxicity
Performance.Show that Chinese medicine hot compress bag of the present invention uses safety.
Long term toxicity test data
1, experimental technique
Random for Cavia porcellus part is become 4 groups, often group 15.Will depilation in guinea pig back spinal column both sides
Agent is uniformly coated with so that it is depilation scope about 40 square centimeters.Clean depilatory, observe 24 little
Often organize Cavia porcellus time after to lose money in a business respectively inventive embodiments 3, embodiment 6 and the hot ironing bag of embodiment 9,
Another group is coated with the every twice-daily of solvent 0.8ml, continuous 30 days, observes the ordinary circumstance of Cavia porcellus,
Experiment is put to death animal after terminating and is carried out hematology, blood biochemical and pathological examination.
2, result
Above-mentioned three groups of medication Cavia porcellus trunks go to hair-fields, have no that local skin has edema, hyperemia, red
Speckle, petechia and ulcer.Medication group and control animals chroma of hair, ingest, extremity movable
Deng matched group no significant difference, blood biochemistry checking, medication group and matched group are all in normal range.
Histopathologic examination, tests each group of heart, liver, kidney and local skin and is showed no obvious pathological changes.
Local skin and whole body important organ are showed no substantially by hot ironing bag long-term prescription of the present invention
Toxic action.Result of the test shows, hot ironing bag experiment safety of the present invention.
Clinical case
1. range of observation and object choice
(1) range of observation: symptom is periodically or aperiodicity mastalgia, pain present be twinge,
Distending pain or have a dull ache.
(2) object choice: be clinical observation object through the cervical vertebra pain patient of multi-treatment poor effect.
(3). criterion of therapeutical effect and therapeutic outcome
Criterion of therapeutical effect: 1. recovery from illness: lump in breast and pain disappear, infrared ray, ultrasound diagnosis prompting breast
Room pathological changes sign disappears；The most effective: lump in breast reduces, pain relief or disappearance, infrared ray
And B ultrasonic prompting breast lesion sign alleviates；The most invalid: lump in breast and pain are unchanged, red
Outside line and ultrasound diagnosis prompting breast lesion sign are unchanged.
2. model case
Case 1: Dong, female, 40 years old, more than bilateral lump in breast year, at ordinary times without pain, does not gives note
Meaning.Closely feel uncomfortable in chest, hypochondriac pain, bilateral distending pain of the breast, and with menstrual phase after, the few color of amount is dark,
Distention and pain in the lower abdomen 2 months.On inspection, having sheet bulk to thicken tissue outside double mammary gland, quality is medium,
Can promote, tenderness is obvious, is all diagnosed as cyclomastopathy through mammary gland color ultrasound, breast molybdenum target inspection,
Double mammary gland outside upper quadrant hypertrophy is heavier.Dimly red tongue, white and thin fur and greasy, rolling pulse.Use the present invention
Embodiment 3 hot ironing bag treats 2 courses for the treatment of, applies each course for the treatment of 10, and mastalgia substantially subtracts
Gently, continual cure 2 courses for the treatment of, on inspection mass reduction half, it is continuing with 2 courses for the treatment of,
Lump in breast and pain disappear, and menstrual phase is normal, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
Case 2: Cao, female, 41 years old, during health check-up, look into breast nodule at local hospital, because tuberosity
Less, just do not give treatment.Recently, patient often feels mammary gland pain, the soreness of waist can not sitting, through doctor
Institute's B ultrasonic is looked into, and tuberosity significantly increases earlier above, and patient treats 2 with the embodiment of the present invention 6 hot ironing bag
The individual course for the treatment of, applying each course for the treatment of 7, pain disappears, and continues to apply 4 courses for the treatment of, and B ultrasonic comes to an end joint
Without.Looking into without recurrence after half a year, tuberosity disappears.
Case 3: Zhang, female, 50 years old, bilateral breast mass companion's pain 2 years, bilateral breast dull pain,
Attach most importance to left side, check oneself several enclosed mass that differ in size in the breast of discovery both sides.On inspection, both sides
Accessible multiple circle or the oval lumps of differing in size of breast, matter is tough, has tenderness, and push away can
Dynamic.Pale tongue, tongue is white, rolling pulse.Mammary gland color ultrasound, breast molybdenum target check, pathological examination is equal
It is diagnosed as cyclomastopathy.2 courses for the treatment of, each course for the treatment of is treated by hot ironing bag embodiment 9 of the present invention
Applying 10, symptom is improved, and pain substantially alleviates, 6 courses for the treatment of of continual cure, lump in breast and pain
Pain is wholly absent, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.
Claims (10)
1. treat a Chinese medicine hot compress bag for cyclomastopathy, including the main bag equipped with principal agent, its feature
Being, described main bag includes the bag being made up and having open side of waterproof fabrics, described
Open side is sealed by the non-woven fabrics that thickness is 1-5mm；The bag of described main bag built with
First content thing and liquid medicine, described first content thing is mainly prepared from by following crude drug:
Iron filings 3-12 weight portion, Herba Schizonepetae 2-6 weight portion, Myrrha 3-9 weight portion, Folium Artemisiae Argyi
1-5 weight portion, Bulbus Fritillariae Thunbergii 1-5 weight portion, Fructus Gleditsia 0.5-3 weight portion, Radix Aucklandiae 0.5-3
Weight portion；
Described liquid medicine is mainly prepared from by following crude drug:
Radix Scrophulariae 10-20 weight portion, Radix Bupleuri 10-20 weight portion, Herba Asari 10-20 weight portion, stone
Dry measure used in former times 5-18 weight portion, mammary gland grass 5-15 weight portion, phlegm-fire grass 5-15 weight portion, Rhizoma Sparganii
3-11 weight portion, mature vinegar 20-45 weight portion.
2. the Chinese medicine hot compress bag treating cyclomastopathy as claimed in claim 1, it is characterised in that
Prepare described first content thing and also include following crude drug:
Radix Glycyrrhizae 3-9 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, eupolyphaga 1-5 weight portion, Spica Prunellae 0.5-3
Weight portion, Olibanum 0.5-3 weight portion.
3. the Chinese medicine hot compress bag treating cyclomastopathy as claimed in claim 1, it is characterised in that
Prepare described liquid medicine and also include following crude drug:
Radix Et Caulis Acanthopanacis Senticosi 5-20 weight portion, Semen Strychni 5-15 weight portion, Ramulus Cinnamomi 5-15 weight portion, Fructus Citri tangerinae
Stalk 1-5 weight portion, Radix Et Rhizoma Rhei 1-5 weight portion, Radix Rhodiolae 1-5 weight portion.
4. the Chinese medicine hot compress bag of the treatment cyclomastopathy as according to any one of claim 1-3, its
Being characterised by, described hot ironing bag also includes equipped with accessory drugs and auxiliary with what main bag open side was connected
Bag, described auxiliary bag includes the bag being made up of non-woven fabrics, the bag of described auxiliary bag built with
Second content, described second content is mainly prepared from by following raw material: far infrared
Ceramics 5-20 weight portion, Actinolitum 15-30 weight portion, Pyritum 10-30 weight portion,
Testa Tritici 10-30 weight portion, Bombyx mori L. 5-20 weight portion；Described far infrared ceramic powder, sun rise
Stone, Pyritum, Testa Tritici and Bombyx mori L. are size-reduced is prepared as the microgranule that particle diameter is 1-100 μm.
5. the Chinese medicine hot compress bag treating cyclomastopathy as claimed in claim 4, it is characterised in that
Described first content thing is prepared from by following crude drug:
Iron filings 8 weight portion, Herba Schizonepetae 4 weight portion, Myrrha 5 weight portion, Folium Artemisiae Argyi 3 weight portion,
Bulbus Fritillariae Thunbergii 3 weight portion, Fructus Gleditsia 1.5 weight portion, the Radix Aucklandiae 1.5 weight portion, Radix Glycyrrhizae 6.5
Weight portion, the Radix Angelicae Dahuricae 3 weight portion, eupolyphaga 3 weight portion, Spica Prunellae 1.5 weight portion, breast
Fragrant 1.5 weight portions；
Described liquid medicine is prepared from by following crude drug:
Radix Scrophulariae 15 weight portion, Radix Bupleuri 15 weight portion, Herba Asari 15 weight portion, Herba Dendrobii 12 weight
Part, mammary gland grass 10 weight portions, phlegm-fire grass 12 weight portions, Rhizoma Sparganii 7 weight portion, mature vinegar
35 weight portions, Radix Et Caulis Acanthopanacis Senticosi 12 weight portion, Semen Strychni 8 weight portion, Ramulus Cinnamomi 8 weight portion,
Radix Platycodonis 3 weight portion, Radix Et Rhizoma Rhei 3 weight portion, Radix Rhodiolae 3 weight portion；
Described second content is prepared from by following crude drug:
Far infrared ceramic powder 10 weight portion, Actinolitum 22 weight portion, Pyritum 20 weight portion,
Testa Tritici 20 weight portion, Bombyx mori L. 15 weight portion.
6. the Chinese medicine hot compress bag treating cyclomastopathy as claimed in claim 4, it is characterised in that
Described hot ironing bag also includes that adjuvant, the ratio of weight and number of described crude drug and adjuvant are
1:0.1-0.6；
Described adjuvant includes that main bag adjuvant, described main bag adjuvant include kaolin 15-35 weight portion,
Carbomer 10-25 weight portion, Quamonium 8-20 weight portion, salicylic acid
Sodium 3-12 weight portion.
7. the Chinese medicine hot compress bag treating cyclomastopathy as claimed in claim 6, it is characterised in that
Described adjuvant also includes that auxiliary bag adjuvant, described auxiliary bag adjuvant include peach kernel oil 20-40 weight
Part and sodium palmitate 5-30 weight portion.
8. the Chinese medicine hot compress bag treating cyclomastopathy as claimed in claim 1, it is characterised in that
The nonwoven layer surface of described auxiliary bag is provided with tearable cover layer, and described cover layer is poly-second
Alkene thin-film covering layer.
9. a preparation method for the Chinese medicine hot compress bag for the treatment of cyclomastopathy as claimed in claim 7, bag
Include following steps:
(1) preparation of first content thing: weigh the iron filings of formula ratio, Herba Schizonepetae, Myrrha, Chinese mugwort
Leaf, Bulbus Fritillariae Thunbergii, Fructus Gleditsia, the Radix Aucklandiae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, eupolyphaga, Spica Prunellae and Olibanum,
Pulverize, cross 60 mesh sieves, obtain first content thing；
(2) preparation of liquid medicine:
(2.1) Radix Scrophulariae of described weight portion, Radix Bupleuri, Rhizoma Sparganii, Radix Et Rhizoma Rhei distillation extraction are taken,
To volatile oil, and collect the aqueous solution after distillation；
(2.2) Herba Asari of formula ratio, Herba Dendrobii, mammary gland grass, phlegm-fire grass, Radix Et Caulis Acanthopanacis Senticosi, horse are weighed
After front son, Ramulus Cinnamomi, Radix Platycodonis, Radix Rhodiolae boiling 3 hours, add step (2.1)
Medicinal residues after middle distillation, boiling twice, each 1 hour, merge decoction liquor, filter
Crossing, after filtration, the aqueous solution with step (2.1) merges, and is concentrated into magma shape, is cooled to room
Temperature, adds ethanol and makes alcohol content be 65%, and stirring stands 24 hours, takes supernatant and return
Receive ethanol, add the mature vinegar of formula ratio, mix homogeneously, obtain liquid medicine；
The preparation of (3) second contents
(3.1) weigh Testa Tritici and the Bombyx mori L. of formula ratio, utilize pulverizer to pulverize, sieve, obtain
Drug particles more than 100 mesh；Testa Tritici and Bombyx mori L. granule are placed in equipped with aqueous buffer solution
Shearing tank in soak 3-5h, wherein, drug particles with the weight ratio of aqueous buffer solution is
1:5-15, then carries out shearing-crushing and obtains micropowder suspension, 30-45 DEG C of temperature after pulverizing
Under the conditions of degree, vacuum drying is utilized to be dried by drug particles suspension, drug particle aggregation
Become thin film, disperseed i.e. to obtain bran micropowder and Bombyx mori L. micropowder；
(3.2) weigh the Actinolitum of formula ratio, put on smokeless stove fire or in suitable container, use
After intense fire heating is calcined to be popular in, soaking and quench in pouring effect of yellow wine into and acting on, taking-up is dried,
Grind；The Pyritum weighing formula ratio grinds, by the Actinolitum ground, Pyritum and remote
Infrared ceramic powder pulverizing mill is prepared as the microgranule of 1500-2000 mesh, with step (3.1)
Testa Tritici microgranule and Bombyx mori L. microgranule mix homogeneously, obtain particulate second content；
(4) preparation of main bag: by first content thing and the liquid medicine mixing and stirring of preparation, add
Enter the kaolin of formula ratio, carbomer, Quamonium and sodium salicylate,
After mix homogeneously, load in main bag and seal, the main bag of cyclomastopathy must be treated；
(5) preparation of auxiliary bag: preparation the second content in add formula ratio peach kernel oil and
Sodium palmitate, after mix homogeneously, loads in auxiliary bag and seals, and must treat mammary gland and increase
Raw auxiliary bag；
(6) the main bag after step (4) being processed and the auxiliary bag after step (5) process are carried out even
Knot combination, must treat the Chinese medicine hot compress bag of cyclomastopathy.
10. the preparation method of the Chinese medicine hot compress bag for the treatment of cyclomastopathy as claimed in claim 9, its feature
Being, the shearing condition in described step (3) is: shearing rotating speed is 1800-2500r/m,
Shear time is 30-60min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610568003.4A CN105963504A (en) | 2016-07-17 | 2016-07-17 | Traditional Chinese medicine hot medicated compress bag for treating hyperplasia of mammary glands and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610568003.4A CN105963504A (en) | 2016-07-17 | 2016-07-17 | Traditional Chinese medicine hot medicated compress bag for treating hyperplasia of mammary glands and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600381A (en) * | 2011-08-25 | 2012-07-25 | 张万坤 | Hot-ironing bag for spur, rheumatism and osteosynthesis and preparation method for same |
| CN103961651A (en) * | 2014-05-19 | 2014-08-06 | 张万坤 | Traditional Chinese medicine ironing bag for treating spur and rheumatism fracture and preparation method thereof |
| CN104491708A (en) * | 2014-12-05 | 2015-04-08 | 陕西去病药业有限公司 | External patch for treating mammitis and breast hyperplasia and relieving breast tumor pain and preparation method of patch for external use |
-
2016
- 2016-07-17 CN CN201610568003.4A patent/CN105963504A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600381A (en) * | 2011-08-25 | 2012-07-25 | 张万坤 | Hot-ironing bag for spur, rheumatism and osteosynthesis and preparation method for same |
| CN103961651A (en) * | 2014-05-19 | 2014-08-06 | 张万坤 | Traditional Chinese medicine ironing bag for treating spur and rheumatism fracture and preparation method thereof |
| CN104491708A (en) * | 2014-12-05 | 2015-04-08 | 陕西去病药业有限公司 | External patch for treating mammitis and breast hyperplasia and relieving breast tumor pain and preparation method of patch for external use |
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