CN105943414B - Cosmetic composition comprising cultured root oil of wild ginseng as active ingredient, method for preparing the same and cosmetic method using the same - Google Patents
Cosmetic composition comprising cultured root oil of wild ginseng as active ingredient, method for preparing the same and cosmetic method using the same Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
Disclosed are a cosmetic composition comprising cultured root oil of wild ginseng as an active ingredient, a method for preparing the same, and a cosmetic method using the same. The cosmetic composition can exhibit moisturizing effect due to the use of natural materials, and contains wild ginseng culture root oil, thus exhibiting anti-inflammatory effect, thereby exhibiting excellent skin moisturizing, anti-inflammatory and anti-wrinkle effects without skin irritation.
Description
Technical Field
The present invention relates to a cosmetic composition comprising cultured root oil of wild ginseng as an active ingredient, a method for preparing the cosmetic composition, and a cosmetic method using the cosmetic composition.
Background
the present invention relates to a cosmetic composition for reducing inflammation in skin, and more particularly, to a cosmetic composition for reducing inflammation in skin, which is characterized in that, as a result of the development of a skin moisturizing material including natural polymers such as animal and plant extracts, collagen, and the like, skin cell activators such as amino acids, vitamins, and the like, or moisturizers such as glycerin, 1, 3-butylene glycol, and the like (korean patent application laid-open No. 2012-0058798), and intercellular lipids constituting the stratum corneum, and effective and thus commonly used polyols, which are present in the skin, such as o-alpha-isoxapric, o-alpha-isoxac, o-isoxac, o-alpha, o-isoxac, o-alpha-isoxac, o-alpha-.
Cosmetic products containing physiologically active materials of natural origin are being actively developed to achieve skin moisturization and reduction of skin inflammation, but the efficacy of the cosmetic products is slight or the use of the cosmetic products may be accompanied by some risks. Therefore, there is a need to develop low risk materials with high skin moisturizing and anti-inflammatory efficacy.
[ citation list ]
[ patent document ]
(patent document 1): korean patent application laid-open No. 2012-0058798
Disclosure of Invention
Accordingly, the present invention has been made keeping in mind the above problems occurring in the related art, and an object of the present invention is to provide a cosmetic composition comprising, as an active ingredient, a physiologically active material of natural origin, and a method for preparing the same.
In order to achieve the above objects, the present invention provides a cosmetic composition comprising oil of cultured roots of wild ginseng as an active ingredient.
In one embodiment of the present invention, the cosmetic composition may be used for skin moisturization, anti-inflammation, or anti-wrinkle.
In another embodiment of the present invention, the cosmetic composition may contain the cultured root oil of wild ginseng at a concentration of 0.1mg/ml to 100 mg/ml.
In yet another embodiment of the present invention, the cosmetic composition may be provided in a formulation of: a skin softening agent, a skin nutrient solution, a nutrient cream, a massage cream, an essence, a gel cream, a mask (pack), a lotion, a face powder, a blush, an eye shadow, a mascara, a concealer (skin cover), a lipstick, a lip gloss, or a foundation.
Further, the present invention provides a method for preparing a cosmetic composition, the method comprising: maturing cultured roots or dregs of cultured roots of wild ginseng in a solvent; and removing the solvent to obtain the wild ginseng culture root oil.
In one embodiment of the present invention, the cosmetic composition may be used for skin moisturization, anti-inflammation, or anti-wrinkle.
In another embodiment of the present invention, the solvent may include water, C1-C4 alcohol, 1, 3-butanediol, acetone, ethyl acetate, butyl acetate, hexane, or chloroform.
Furthermore, the present invention provides a cosmetic method comprising applying the above cosmetic composition to the skin.
According to the present invention, the cosmetic composition includes natural materials to thereby ensure moisturizing efficacy and impart anti-inflammatory efficacy due to the use of the cultured root oil of wild ginseng, and thus can exhibit excellent moisturizing and anti-inflammatory efficacy without skin irritation.
Also, according to the present invention, the cosmetic composition can effectively produce collagen, thereby exhibiting anti-wrinkle effects.
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Detailed Description
The present invention relates to a cosmetic composition comprising cultured root oil of wild ginseng as an active ingredient, and to a method for preparing the same.
The present inventors have adopted cultured roots of wild ginseng as a cosmetic composition material which does not irritate the skin and contains an effective physical active ingredient, i.e., saponin, and thus is considered to exhibit skin moisturizing effect, anti-inflammatory effect, and anti-wrinkle effect. Generally, ginseng or red ginseng is known to contain abundant saponins, but ginseng has disadvantages of requiring a long cultivation period and difficulty in repeated cultivation, which makes it difficult to efficiently supply ginseng. However, cultured roots of wild ginseng enable repeated production due to its short culture period and relatively simple production process, and its saponin content can be controlled during culture by inducer treatment. Therefore, the cultured root of wild ginseng is considered to be a good natural material. As cultured roots of natural wild ginseng are artificially induced and proliferated, oil extracted from the cultured roots of wild ginseng has been found to exhibit high moisturizing, anti-inflammatory and anti-wrinkle effects, and thus cosmetic compositions containing the cultured roots of wild ginseng have been developed.
Hereinafter, a detailed description will be given of the present invention.
The invention provides a cosmetic composition containing wild ginseng culture root oil as an active ingredient.
The cosmetic composition contains oil extracted from cultured roots of wild ginseng that have been cultured by artificially inducing and proliferating cultured roots of natural wild ginseng, and thus is useful for skin moisturization, inflammation reduction, and wrinkle resistance.
The wild ginseng culture root oil may be obtained from wild ginseng culture roots or wild ginseng culture root residues, and may have a concentration of 0.1 to 100 mg/ml. The cultured root oil of wild ginseng comprises various components, and comprises oil and fat, phytosterol, phospholipid and polyacetylene as main components. Specifically, the wild ginseng culture root oil comprises 70 to 90 parts by weight of oil and fat, 0.1 to 15 parts by weight of phytosterol, 0.1 to 10 parts by weight of phospholipid, and 0.1 to 5 parts by weight of polyacetylene, based on the total weight of the wild ginseng culture root oil.
The cosmetic composition may be provided in various formulations, and is preferably provided in the form of, for example: skin toner (skin toner), skin nutrient solution (lotion), nourishing cream, massage cream, essence, gel cream, facial mask, lotion, honey powder, blush, eye shadow, mascara, concealer, lipstick, lip gloss, or foundation.
Furthermore, the present invention proposes a process for preparing a cosmetic composition, said process comprising: maturing the cultured root or the residue of the cultured root of wild ginseng in a solvent, and removing the solvent to obtain the cultured root oil of wild ginseng.
The method may further comprise drying and filtering the cultured root or residue of wild ginseng after maturing the cultured root or residue of wild ginseng in the solvent but before removing the solvent. This filtering may be performed one or more times in order to prevent contamination and enable long-term storage of the product.
The steps of maturing the cultured wild ginseng root or the cultured wild ginseng root residue in the solvent and removing the solvent may be performed in the following manner: making cultured root or residue of wild ginseng at low or room temperatureImmersing in a solvent and storing for a predetermined period of time or heating, whereby the cultured root oil of wild ginseng can be extracted. The extraction process is not particularly limited, but preferably includes ultrasonic extraction, CO2Supercritical extraction, and the like.
The solvent may include water, C1-C4 alcohol, 1, 3-butanediol, acetone, ethyl acetate, butyl acetate, hexane, or chloroform. Preferably hexane or ethyl acetate is used.
In a preferred embodiment of the present invention, the cultured root oil of wild ginseng is obtained by the following steps: adding 1 to 20L of a solvent to about 1kg of cultured roots or dregs of cultured roots of wild ginseng, and extracting oil from the cultured roots or dregs of cultured roots of wild ginseng at 1 to 35 ℃, preferably at 24 to 35 ℃ for 10 minutes to 24 hours, preferably for 2 to 24 hours. The extract thus obtained was dried, filtered and additionally concentrated under reduced pressure to remove the solvent. If necessary, the matured extract can be stored at room temperature after drying and filtration.
Furthermore, the present invention proposes a cosmetic method comprising applying the above cosmetic composition to the skin.
The invention is illustrated in detail by the following examples, which are set forth merely to illustrate the invention. The present invention is not limited to such examples and may be variously modified and changed.
Preparation of example 1
20L of hexane was added to 1kg of dried tissue culture roots of wild ginseng, sufficiently matured at room temperature for 24 hours, and filtered using filter paper (5C, 185mm, manufactured by Toyo Roshi Kaisha, Ltd., Japan) to obtain a filtrate, which was then concentrated under reduced pressure to remove hexane, followed by sufficiently matured at room temperature for 24 hours and filtered using filter paper (5C, 185mm, manufactured by Toyo Filter paper Co., Ltd., Japan), thereby obtaining wild ginseng root culture oil.
Preparation of example 2
20L of hexane was added to 1kg of dried tissue culture root residue of wild ginseng (the residue of wild ginseng culture root is mainly produced by extraction of wild ginseng culture root with water or a solvent), sufficiently aged at room temperature for 24 hours, and filtered using a filter paper (5C, 185mm, manufactured by Toyo Filter paper Co., Ltd., Japan) to obtain a filtrate, which was then concentrated under reduced pressure to remove hexane, and then sufficiently aged at room temperature for 24 hours and filtered using a filter paper (5C, 185mm, manufactured by Toyo Filter paper Co., Ltd., Japan), thereby obtaining a residue oil of wild ginseng culture root.
Preparation of example 3
To 1kg of dried tissue culture root of wild ginseng, 20L of ethyl acetate was added, sufficiently aged at room temperature for 24 hours, and filtered using a filter paper (5C, 185mm, manufactured by eastern filter paper co., japan) to obtain a filtrate, which was then concentrated under reduced pressure to remove ethyl acetate, followed by sufficiently aged at room temperature for 24 hours and filtered using a filter paper (5C, 185mm, manufactured by eastern filter paper co., japan) to obtain an oil of wild ginseng culture root.
Preparation of example 4
To 1kg of dried tissue culture root residue of wild ginseng, 20L of ethyl acetate was added, sufficiently aged at room temperature for 24 hours, and filtered using a filter paper (5C, 185mm, manufactured by eastern filter paper co., japan) to obtain a filtrate, which was then concentrated under reduced pressure to remove ethyl acetate, and then sufficiently aged at room temperature for 24 hours and filtered using a filter paper (5C, 185mm, manufactured by eastern filter paper co., japan) to obtain a cultured root residue of wild ginseng.
Test example 1: measuring moisturizing effect of wild ginseng culture root oil
In order to evaluate moisturizing efficacy of the cosmetic composition according to the present invention, the moisture content of the skin was measured. Formulations in preparation examples 1 to 4 with or without oil as shown in table 1 below were prepared, and the moisture content of the skin of twenty women between 20 and 50 years old before and after applying the formulations was measured by the following method after preparation. Specifically, a skin moisture content meter (Corneometer) CM 825, courag and karaki karge, germany was used&Khazaka, Germany)) the moisture content of the skin surface was determined by skin capacitance. Each sample was measured at 2.0mg/cm2Is uniformly applied to wait for 1 hour in the room before testingOn a portion of one upper arm of the subject and no sample is administered on a corresponding portion of the other upper arm of the subject to serve as a control. Skin moisture content was measured immediately before and after application, and at 1 hour, 3 hours, and 5 hours after application. The results are shown in table 2 below. As shown in table 2, the measured values were higher on the applied parts in examples 1 to 4, thereby exhibiting excellent moisturizing efficacy.
[ Table 1]
[ Table 2]
Test example 2: measuring anti-inflammatory effect of wild ginseng culture root oil
the skin formulations of examples 1-4 and comparative example 1 were evaluated for intracellular inflammation efficacy based on the amount of β -hexosaminidase released using a composition purchased from the ATCC (American Type Culture Collection, USA) and at 37 ℃ and 5% CO2Human fibroblast cell line CCD-1064SK (CRL-2076), mouse macrophage cell line RAW264.7 (TIB-71) and rat mast cell line RBL-2H3(CRL-2256) cultured in a cell culture incubator (ELITE II, Rake GmbH (Revco), USA). The respective media for CCD-1064SK, RAW264.7 and RBL-2H3 were IMDM (Dulbecco's medium modified by Iscove (Iscove)), DMEM (eagle's medium modified by Dulbecco) and MEM (minimal essential medium) purchased from Gibbick corporation (Gibco) (USA). FBS (fetal bovine serum, gibick, usa) was added to each medium (10% FBS was added to the medium for CCD-1064SK and RAW264.7, and 15% FBS was added to the medium for RBL-2H 3), and1% antibiotic-antifungal agent solution (Gibbck, USA) was added, then culture was performed, treatment with DNP-HSA (10. mu.g/ml), reaction was performed for 1 hour, and left to stand in an ice bath for 10 minutes after which the reaction was terminated 20. mu.L of the supernatant was transferred to a 96-well plate, 80. mu.L of substrate buffer (1mM 4-p-nitrophenyl-N-acetyl-b-D-glucosaminide, 0.05M sodium citrate, pH 4.5) was added, and cultured at 37 ℃ for 30 minutes, after which 200. mu.L of stop solution was added to each well to terminate the reaction, after which absorbance at 405nm was measured, the amount of released β -hexosaminidase in examples 1 to 4 was decreased as shown in Table 3 below according to the measurement result of the amount of released β -hexosaminidase, therefore, examples 1 to 4 were effective in inhibiting inflammation.
[ Table 3]
| Example 1 | Example 2 | Example 3 | Example 4 | Comparative example 1 | |
| amount of β -hexosaminidase released | 82％ | 86％ | 75％ | 80％ | 100％ |
Test example 3: cytotoxicity assays
3.1 cell culture for cytotoxicity assays
A human fibroblast line CCD-1064SK (CRL-2076), a mouse macrophage line RAW264.7 (TIB-71) and a rat mast cell line RBL-2H3(CRL-2256) purchased from ATCC (American type culture Collection, USA) were used. The respective media of CCD-1064SK, RAW264.7 and RBL-2H3 were IMDM (durbeck medium modified by evacuff), DMEM (eagle medium modified by durbeck) and MEM (minimal essential medium) purchased from gibick corporation (usa), and FBS (fetal bovine serum, gibick corporation, usa) was added to each medium (for CCD-1064SK and RAW264.7, 10% FBS was added to the medium, and for RBL-2H3, 15% FBS was added to the medium), and 1% antibiotic-antifungal agent solution (gibick corporation, usa) was added, thereby culturing the cells. All cells used were at 37 ℃ and 5% CO2In a cell culture incubator (ELITE II, Rake, USA).
3.2 cytotoxicity test of cultured root oil of wild ginseng
Cytotoxicity was measured as follows using MTT (thiazole blue tetrazolium bromide, Sigma, usa) method (journal of immune methods, 141(1), 15 (1991)). The MTT method is used to measure toxicity or cell proliferation according to the following principle: under the action of succinate dehydrogenase in mitochondria of living cells, the yellow water-soluble salt MTT is reduced into blue-violet water-insoluble MTT formazan. CCK-1064SK fibroblasts cultured by the above method were cultured at 1X 105The density of individual cells/well was seeded into 24-well plates (niken (Nunc), usa), cultured for 1 day, transferred to serum-free IMDM, each of the oils of preparation examples 1 to 4 was added at different concentrations, and cultured for 24 hours. The prepared MTT solution having a concentration of 2.5mg/ml was added at 0.1 ml/well and allowed to react at 37 ℃ for 4 hours, after which the MTT solution was removed and DMSO (dimethyl sulfoxide) was added at 0.5 ml/well. MTT formazan is dissolved at room temperature, and the absorbance at 570nm is measured, andand compared to the absorbance of the negative control. The results are shown in table 4 below. As shown in table 4, the cultured root oil of wild ginseng of each of preparation examples 1 to 4 exhibited high cell viability (viatility) in the skin cell CCK-1064SK and thus had almost no cytotoxicity.
[ Table 4]
Test example 4: measurement of collagen biosynthesis of wild ginseng culture root oil
Skin wrinkling is caused by a lack of collagen, and collagen is the main protein constituting the dermis of the skin and acts to maintain the structure and elasticity of the skin. With age, the production of collagen becomes less and its decomposition increases, thereby causing a depression of the dermal layer of the skin, thereby generating wrinkles in the skin. For anti-wrinkle efficacy, collagen biosynthesis was evaluated.
4.1 measurement of the amount of biosynthetic collagen
In order to evaluate the anti-wrinkle efficacy of the cosmetic composition according to the present invention, a collagen biosynthesis promotion test using fibroblast (Sircol) was performedTMSoluble collagen assay Kit (Silcol. simple collagen assay Kit)).
Cultured human fibroblasts were aliquoted into media containing 5% FBS to achieve 1X 10 in 12-well cell culture dishes5Individual cells/well and subsequently cultured for 24 hours. In addition, the wild ginseng culture root oil was diluted to various concentrations in a medium containing 2% FBS, added to the cells, cultured for 48 hours, and then used for the following tests. To determine the actual increase in the amount of collagen synthesized in fibroblasts, a soluble collagen assay kit was purchased from bayer corporation (Biocolor), and the amount of collagen was measured by the test method mentioned in the product manual. The collagen assay kit is a quantitative method based on the coupling of a staining reagent to collagen, which is introduced into the culture medium during cell culture. In particular, the amount of the solvent to be used,1ml of staining reagent (including picric acid and sirius red reagent solution) is added to 100. mu.L of culture supernatant and reacted for 30 minutes (depending on the amount of collagen produced, culture broth can be concentrated, or 200. mu.L of culture supernatant can be reacted with 1ml of staining reagent). Sirius red is specifically conjugated to collagen as an anionic dye. After the reaction for 30 minutes, the reaction solution was centrifuged at a centrifugal force of 12,000 Xg or more for 10 minutes to precipitate the collagen-dye complex. To the precipitate was added 1.0ml of an alkaline agent, and thereby it was dissolved at room temperature for 5 minutes. The absorbance of the above solution was measured at 540nm using an absorption spectrophotometer (UVmax, Molecular devices, USA). The results are shown in table 5 below, and compared with the absorbance of the non-test group to evaluate the collagen biosynthesis promoting efficacy.
[ Table 5]
The following is a description of a formulation of a cosmetic composition for skin moisturization and inflammation reduction.
A formulation of a cosmetic composition containing cultured root oil of wild ginseng according to the present invention is shown, but the present invention is not limited thereto.
Formulation example 1
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into a skin softening agent as shown in table 6 below.
[ Table 6]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| 1, 3-butanediol | 2.00 |
| Glycerol | 3.00 |
| Oleyl alcohol | 2.00 |
| Polysorbate 20 | 1.00 |
| Ethanol | 6.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 2
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into a skin nutrient solution (emulsion) as shown in table 7 below.
[ Table 7]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| 1, 3-butanediol | 4.00 |
| Glycerol | 3.00 |
| Oleyl alcohol | 0.50 |
| Polysorbate 20 | 1.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 3
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into a nourishing cream, as shown in table 8 below.
[ Table 8]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Propylene glycol | 5.00 |
| Glycerol | 5.00 |
| Triethanolamine | 0.50 |
| Tocopheryl acetate | 1.00 |
| Liquid paraffin | 5.00 |
| Squalane | 5.00 |
| Macadamia nut oil | 15.00 |
| Polysorbate 60 | 1.00 |
| Sorbitan sesquioleate | 1.00 |
| Carboxylic acid polymers | 0.20 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 4
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into massage cream as shown in table 9 below.
[ Table 9]
Formulation example 5
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into essences as shown in table 10 below.
[ Table 10]
| Composition (I) | Content (wt%) |
| Cultivation of wild ginsengRoot oil | 2.00 |
| 1, 3-butanediol | 2.00 |
| Glycerol | 5.00 |
| Triethanolamine | 0.27 |
| Carboxylic acid polymers | 0.20 |
| Xanthan gum | 0.10 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 6
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into gel cream as shown in table 11 below.
[ Table 11]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Propylene glycol | 20.00 |
| Carbomer | 20.00 |
| Polysorbate 60 | 0.50 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 7
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into a mask as shown in table 12 below.
[ Table 12]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| 1, 3-butanediol | 5.00 |
| Polyvinyl alcohol | 12.00 |
| Polyvinylpyrrolidone | 2.00 |
| Ethanol | 8.00 |
| Polyvinyl acetate | 1.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 8
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into an emulsion as shown in table 13 below.
[ Table 13]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| 1, 3-butanediol | 5.00 |
| Polyvinyl alcohol | 12.00 |
| Polyvinylpyrrolidone | 2.00 |
| Ethanol | 8.00 |
| Polyvinyl acetate | 1.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Formulation example 9
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into honey powder as shown in table 14 below.
[ Table 14]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Sericite | 10.00 |
| Bismuth oxychloride | 15.00 |
| Mica | 10.00 |
| Phenyl trimethyl polysiloxane | 5.00 |
| Coloring agent | 1.50 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Talcum powder | The rest part |
| Total up to | 100 |
Formulation example 10
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into blush, as shown in table 15 below.
[ Table 15]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Mica | 15.00 |
| Bismuth oxychloride | 5.00 |
| Titanium dioxide | 5.00 |
| Phenyl trimethyl polysiloxane | 5.00 |
| Coloring agent | 8.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Sericite | The rest part |
| Total up to | 100 |
Formulation example 11
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into eye shadow, as shown in table 16 below.
[ Table 16]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Sericite | 10.00 |
| Bismuth oxychloride | 10.00 |
| Titanium dioxide | 5.00 |
| Phenyl trimethyl polysiloxane | 5.00 |
| Coloring agent and pearl powder | 10.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Mica | The rest part |
| Total up to | 100 |
Formulation example 12
The cosmetic composition containing cultured root oil of wild ginseng was formulated into mascara, as shown in table 17 below.
[ Table 17]
Formulation example 13
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into concealer cream as shown in table 18 below.
[ Table 18]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Squalane | 15.00 |
| Diisostearyl maleate | 10.00 |
| Hard paraffin (Paraffin wax) | 2.00 |
| Carnauba wax | 3.00 |
| Titanium dioxide | 10.00 |
| Nylon powder | 5.00 |
| Mica | 5.00 |
| Coloring agent | 1.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Paraffin (paraffin) | The rest part |
| Total up to | 100 |
Formulation example 14
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into lipstick, as shown in Table 19 below.
[ Table 19]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Lanolin oil | 15.00 |
| Oleyl alcohol | 10.00 |
| Candelilla wax | 8.00 |
| Carnauba wax | 3.00 |
| Coloring agent and pearl powder | 10.00 |
| Preservative | 0.20 |
| Essence | 0.20 |
| Diisostearyl maleate | The rest part |
| Total up to | 100 |
Formulation example 15
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into lip gloss, as shown in table 20 below.
[ Table 20]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Polybutylene | 35.50 |
| Lanolin oil | 15.00 |
| Oleyl alcohol | 10.00 |
| Beeswax (wax) | 5.00 |
| Coloring agent and pearl powder | 10.00 |
| Preservative | 0.20 |
| Essence | 0.20 |
| Diisostearyl maleate | The rest part |
| Total up to | 100 |
Formulation example 16
The cosmetic composition containing the cultured root oil of wild ginseng was formulated into foundation as shown in table 21 below.
[ Table 21]
| Composition (I) | Content (wt%) |
| Wild ginseng culture root oil | 2.00 |
| Cyclopentasiloxane | 25.00 |
| Soap soil | 3.00 |
| PEG-10 Dimethicone | 3.00 |
| Carnauba wax | 5.00 |
| C12-15 alkyl benzoates | 20.00 |
| Iron oxide | 3.00 |
| Titanium dioxide | 5.00 |
| Sodium chloride | 2.00 |
| Preservative | 0.20 |
| Essence | 0.10 |
| Purified water | The rest part |
| Total up to | 100 |
Although the preferred embodiment of the present Rich has been disclosed for the sake of in-strain clarity, those skilled in the art understand that modifications, additions and substitutions are possible in a situation where the scope and spirit of the Rich is not.
Claims (4)
1. A cosmetic composition comprises cultured root oil of wild ginseng as an active ingredient, wherein,
the wild ginseng culture root oil is extracted by hexane or ethyl acetate at the temperature of 24-35 ℃ for 2-24 hours,
wherein 1L to 20L of said hexane or ethyl acetate is added to each 1kg of cultured roots of the wild ginseng;
wherein the cosmetic composition is used for skin moisturizing, anti-inflammatory, or anti-wrinkle.
2. The cosmetic composition according to claim 1, wherein the cosmetic composition contains the cultured root oil of wild ginseng at a concentration of 0.1 to 100 mg/ml.
3. The cosmetic composition of claim 1, wherein the cosmetic composition is provided in a formulation of: a skin softening agent, a skin nutrient solution, a nutrient cream, a massage cream, an essence, a gel cream, a mask, a lotion, a honey powder, a blush, an eye shadow, a mascara, a concealer, a lipstick, a lip gloss, or a foundation.
4. A process for preparing a cosmetic composition, wherein the process comprises:
curing the cultured root or the cultured root residue of the wild ginseng in a solvent at 24 to 35 ℃ for 2 to 24 hours; and
removing the solvent to obtain wild ginseng culture root oil,
the solvent comprises ethyl acetate or hexane,
wherein 1L to 20L of said hexane or ethyl acetate is added to each 1kg of cultured roots of the wild ginseng;
wherein the cosmetic composition is used for skin moisturizing, anti-inflammatory, or anti-wrinkle.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150032347A KR101836354B1 (en) | 2015-03-09 | 2015-03-09 | Cosmetic composition comprising oil of cultured root of wild ginseng |
| KR10-2015-0032347 | 2015-03-09 |
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| Publication Number | Publication Date |
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| CN105943414A CN105943414A (en) | 2016-09-21 |
| CN105943414B true CN105943414B (en) | 2020-06-02 |
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| CN201610129722.6A Active CN105943414B (en) | 2015-03-09 | 2016-03-08 | Cosmetic composition comprising cultured root oil of wild ginseng as active ingredient, method for preparing the same and cosmetic method using the same |
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| Country | Link |
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| KR (1) | KR101836354B1 (en) |
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| KR101844356B1 (en) * | 2017-12-06 | 2018-04-02 | 주식회사 화진바이오코스메틱 | Cultivated wild ginseng root oil with enhanced fatty acid content and manufacturing method thereof |
| KR101878945B1 (en) * | 2017-12-22 | 2018-07-16 | 주식회사 화진바이오코스메틱 | Cultivated wild ginseng root oil with enhanced fatty acid content and manufacturing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100493845B1 (en) * | 2001-07-04 | 2005-06-08 | 한국화장품주식회사 | Whitening cosmetic composition containing the extract of mountain ginseng adventitious roots |
| CN100998313B (en) * | 2006-01-13 | 2011-04-27 | Cbn生物科技株式会社 | Production method of ginseng culture root extraction with high content of ginsenoside and its use |
| US20100055212A1 (en) * | 2007-01-17 | 2010-03-04 | Jong-Wan Choi | Cosmetic composition comprising tissue cultured panax ginseng c.a. meyeradventitious root itself and a preparing method thereof |
| KR100992042B1 (en) * | 2008-04-16 | 2010-11-04 | 장수산삼 영농조합법인 | preparation for cosmetic composition containg ginseng extract stabilized by nanoliposome |
| CA2732058C (en) * | 2008-06-13 | 2014-09-23 | Unhwa Corporation | Anti-aging or antioxidant composition containing plant stem cell line derived from cambium of panax ginseng |
| KR20100083888A (en) * | 2009-01-15 | 2010-07-23 | 주식회사 한국화장품제조 | A cosmetic composition comprising tissue cultured panax ginseng adventitious roots extract and an preparing method thereof |
| CN102086425B (en) * | 2009-12-02 | 2013-10-09 | 吉林省宏久生物科技股份有限公司 | Extraction and separation technology for ginseng essential oil |
| KR101796694B1 (en) | 2010-11-30 | 2017-11-13 | (주)아모레퍼시픽 | Cosmetic composition for improving skin whitening and lifting |
| KR101419587B1 (en) * | 2012-06-26 | 2014-07-14 | 주식회사 한국인삼공사 | Composition for Promoting Regeneration of Skin Comprising Ginseng Oil as Active Ingredient |
| KR20150037115A (en) * | 2013-09-30 | 2015-04-08 | 주식회사 함양산양삼 | Manufacturing method of herb extracts for anti-wrinkling and skin whitening, herb extracts for anti-wrinkling and skin whitening manufactured by the same and cosmetic composition for anti-wrinkling and skin whitening containing the same |
| CN104257556A (en) * | 2014-09-19 | 2015-01-07 | 吉林吉福参生物开发股份有限公司 | Ginseng essence eye cream and preparation method thereof |
| KR101525873B1 (en) * | 2015-03-18 | 2015-06-04 | (주)에스디생명공학 | Cosmetic composition containing Manufacturing method and Cultured wild Ginseng Roots, Hedysarum ussuriensis, Sophora flavescens and Adenophora triphylla by two-stage fermentation for improving skin |
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2015
- 2015-03-09 KR KR1020150032347A patent/KR101836354B1/en active IP Right Grant
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| Publication number | Publication date |
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| KR20160108917A (en) | 2016-09-21 |
| KR101836354B1 (en) | 2018-03-09 |
| CN105943414A (en) | 2016-09-21 |
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