CN105920331A - Production process for rhizoma polygonati preparata - Google Patents

Production process for rhizoma polygonati preparata Download PDF

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Publication number
CN105920331A
CN105920331A CN201610490765.7A CN201610490765A CN105920331A CN 105920331 A CN105920331 A CN 105920331A CN 201610490765 A CN201610490765 A CN 201610490765A CN 105920331 A CN105920331 A CN 105920331A
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China
Prior art keywords
sealwort
rhizoma polygonati
polygonati preparata
steamer
production technology
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CN201610490765.7A
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Chinese (zh)
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石丁
石一丁
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Individual
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Priority to CN201610490765.7A priority Critical patent/CN105920331A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Fruits And Vegetables (AREA)

Abstract

The invention relates to a production process for rhizoma polygonati preparata. The production process comprises the following steps of selecting medicinal materials, washing the medicinal materials, soaking, steaming the medicinal materials, baking the medicinal materials, and packaging. The rhizoma polygonati preparata inherits from unique traditional Chinese medicines in China, and is in an irregular thick piece, dark brown to black in surface with gloss, brown to light brown in center and visible in tendon and vein dots; the prepared rhizoma polygonati is soft in texture, sweet in taste and slight in wine aroma and has the efficacies of boosting Qi and nourishing Yin, strengthening spleen, moistening lung and tonifying kidney, and is used for treating spleen and stomach Qi deficiency, tired body and debility, stomach Yin deficiency, dry mouth and reduced appetite, lung deficiency and cough caused by dryness, overstrain cough and hemoptysis, insufficiency of blood and essence, soreness and weakness of waist and knees, premature graying hair and internal heat dispersion-thirst. A preparation method for the prepared rhizoma polygonati is simple, facilitates batch production, meets modern pharmaceutical standards, and accords with standardization requirements; the produced rhizoma polygonati preparata is stable in quality.

Description

RHIZOMA POLYGONATI PREPARATA production technology
Technical field
The present invention relates to pharmaceutical technology field, specifically refer to a kind of RHIZOMA POLYGONATI PREPARATA production technology.
Background technology
Traditional Chinese medicine is the treasure of the Chinese nation, is made that tremendous contribution for multiplying and being prosperous of the Chinese nation.Tradition doctor The treatment concept learned the most gradually is accepted by the world, and traditional medicine is more and more paid close attention to by international community, in world wide Growing to the demand of traditional Chinese medicine, this is that the development of traditional Chinese medicine provides wide space.1997, lead with the Ministry of Science and Technology Head, is participated in by departments such as the Ministry of Public Health, State Food and Drug Administration, State Administration of Traditional Chinese Medicines, has set up national new drug Leading group, organizes national over hundreds of expert to propose the planning of modernization of Chinese medicine development, starts and implement modernization of Chinese medicine work Make.The TCM Modernization work in the whole nation has been achieved for impressive progress: R&D mode is the most perfect, and the capability of independent innovation is notable Strengthen;Successfully developing a collection of Chinese medicine new varieties, the important function of Chinese herb prevention disease is played further;Formulate one The Chinese medicine basic standard that batch weight is wanted and meet the scientific and normal of character of traditional Chinese medicine, standards of Chinese traditional medicine industry normative construction wins initial success.With Time, the modernization of Chinese medicine improve people's health level, increase farmers' income, the aspect such as preserve the ecological environment also has played notable work With.Before in April, 2005, having established 448 Good Agricultural Practice bases, 18 province GAP areas reach interiorly 920000 hectares.Meanwhile, along with production technology and the breakthroughs of technique such as supercritical extract, UF membrane, fluidized granulatings, Chinese medicine produces work Technology, equipment are greatly improved, and traditional Chinese medicine enterprise scale, benefit the most constantly promote.Contain medicinal plant farming, Chinese medicine industry, in The modern TCM industry chain of pharmacist's industry constantly improves and development.
RHIZOMA POLYGONATI PREPARATA passes on from the distinctive Chinese Traditional Medicine of China, in irregular sheet.Surface sepia, to black, has light Pool, center brown is to light brown, it is seen that muscle arteries and veins point.Matter is relatively soft.Taste is sweet, and micro-have wine aroma.Its effect boosting qi and nourishing yin, strong Spleen, moistening lung, kidney-nourishing.For deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, dry food is few, deficiency syndrome of the lung cough caused by dryness, and labor is coughed hemoptysis, and essence and blood is not Foot, soreness and weakness of waist and knees, poliosis, interior heat is quenched one's thirst.But traditional RHIZOMA POLYGONATI PREPARATA preparation method is numerous and diverse, it is unfavorable for batch production, does not the most also have There is a kind of adaptation modern pharmaceutical standard, meet Standardization Requirement, stay-in-grade RHIZOMA POLYGONATI PREPARATA production technology.
Summary of the invention
The purpose of the present invention is contemplated to solve the above-mentioned problems in the prior art, it is provided that a kind of adaptation modern pharmaceutical Standard, meets Standardization Requirement, stay-in-grade RHIZOMA POLYGONATI PREPARATA production technology.
The purpose of the present invention is achieved through the following technical solutions:
RHIZOMA POLYGONATI PREPARATA production technology, comprises the following steps:
One, select medicine: weigh the sealwort raw material of a certain amount of material, operating personnel take sealwort one by one, observe under bright light, will Go mouldy, medicinal material of damaging by worms is rejected, and removes qualified sealwort surface fibrous root, it is ensured that sealwort smooth surface, smooth, qualified sealwort is put into week Turning proceeds between wash after basket is weighed, and collects discarded object, seals and proceed to refuse depot after being weighed by discarded object;
Two, wash: the medicinal material after step one selects medicine is proceeded to wash district, is laid in wash basket, then uses with giant Circulating water is rinsed to without silt, scrubs clean the silt brush in a few surface out-of-flatness medicinal material crack, then will Medicinal material after washing proceeds to, in Turnround basket, be placed on draining rack;
Three, soak: weigh the yellow rice wine of clean medicinal material weight 3 times, be divided into many parts together with the sealwort cleaned through step 2, be respectively put into In multiple stainless steel casks, cover bung airtight, after soaking 48 hours, sealwort medicinal material in bucket is moved to Turnround basket;
Four, steaming the medicinal hebrs: be laid in food steamer by the sealwort after step 3 is soaked, overlays steamer successively by the food steamer installing sealwort On, food steamer stacks steamer cover on bonnet, opens steamer heating, starts timing, steaming the medicinal hebrs 12 after food steamer top layer starts to emit vapour Hour, after the time arrives, stopping heating, open steamer cover, the sealwort after steaming after temperature is down to below 50 DEG C takes out tiling Drip pan lets cool and receives after water to sealwort surface, be again laid in food steamer and repeat this step 3 time, altogether after steaming the medicinal hebrs four times, will Sealwort takes out and is laid in spreading for cooling 2 hours in stainless steel drip pan;
Five, medicine is dried: be placed in by the drip pan filling sealwort of spreading for cooling after step 4 steaming the medicinal hebrs on baking car, push in drying room, close and dry Door, controls baking temperature, at 45 DEG C~55 DEG C, to be dried material, starts timing after temperature reaches 45 DEG C, every 1 little Shi Kaiqi ventilation fan row's temperature 10 minutes, is dried after 24 hours and closes drying room, baking car is pushed out to spreading for cooling district and lets cool and i.e. obtain RHIZOMA POLYGONATI PREPARATA;
Six, packaging: according to packing instructions, the RHIZOMA POLYGONATI PREPARATA let cool in step 5 is dispensed.
In above step one, qualified sealwort weight should be the 98%~100% of raw material weight with the conjunction of discarded object weight.
In above step three, the concentration of yellow rice wine is 8 °~10 °.
In above step three, every part of sealwort Weight control is within 100kg.
In above step four, the sealwort thickness in food steamer must not exceed 2/3rds of food steamer.
In above step four, the food steamer that each steamer stacks must not exceed 5 cages.
In above step four, during sealwort spreading for cooling, the thickness in drip pan should be between 2cm~3cm.
In above step six, loading amount should be no less than the 97% of mark amount.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Weigh the sealwort raw material of 500kg, operating personnel take sealwort one by one, observe under bright light, will go mouldy, damage by worms Medicinal material is rejected, and removes qualified sealwort surface fibrous root, it is ensured that sealwort smooth surface, smooth, qualified sealwort is put into Turnround basket and weighs After proceed between wash, collect discarded object, after discarded object is weighed seal proceed to refuse depot, the medicinal material after selecting medicine is laid in and washes In medicine basket, then it is rinsed to without silt, to the mud in a few surface out-of-flatness medicinal material crack with giant circulating water Sand brush scrubs clean, and the medicinal material after then washing proceeds to, in Turnround basket, be placed on draining rack;By clean sealwort together It is divided into 5 parts, is respectively put in 5 stainless steel casks, weigh the yellow rice wine of clean medicinal material weight 3 times, be divided into 5 parts, be respectively put into and fill Huang In 5 stainless steel casks of essence, cover bung airtight, after soaking 48 hours, sealwort medicinal material in bucket is moved to Turnround basket, then by sealwort Being laid in food steamer, the sealwort thickness in food steamer must not exceed 2/3rds of food steamer, is stacked successively by the food steamer installing sealwort On steamer, the food steamer on each steamer is limited with 5 layers, and food steamer stacks steamer cover on bonnet, opens steamer heating, waits to steam Cage top layer starts timing, steaming the medicinal hebrs 12 hours after starting to emit vapour, stop heating, open steamer cover, treat that temperature is down to after the time arrives Sealwort after steaming after less than 50 DEG C takes out to be laid in drip pan and lets cool to the receipts water of sealwort surface, is again laid in food steamer, Repeat steaming the medicinal hebrs three times under the same conditions, altogether after steaming the medicinal hebrs four times, sealwort is taken out that to be laid in spreading for cooling 2 in stainless steel drip pan little Time, during sealwort spreading for cooling, the drip pan filling sealwort should be placed on baking car, push baking between 2cm~3cm by the thickness in drip pan Fang Zhong, closes drying room door, controls baking temperature, at 45 DEG C~55 DEG C, to be dried material, open after temperature reaches 45 DEG C Beginning timing, every 1 hour unlatching ventilation fan row's temperature 10 minutes, close drying room after being dried 24 hours, baking car is pushed out to spreading for cooling district and puts Cold i.e. obtain RHIZOMA POLYGONATI PREPARATA, according to packing instructions, carry out dispensing.
The above-mentioned technology design merely illustrating the present invention and feature, its objective is to be to allow the ordinary skill in this area Personnel will appreciate that the content of invention and implement according to this, can not limit the scope of the invention.Every according in the present invention The change of the equivalence done by the essence held or modification, all should contain in protection scope of the present invention.

Claims (8)

1. RHIZOMA POLYGONATI PREPARATA production technology, comprises the following steps:
One, select medicine: weigh the sealwort raw material of a certain amount of material, operating personnel take sealwort one by one, observe under bright light, will Go mouldy, medicinal material of damaging by worms is rejected, and removes qualified sealwort surface fibrous root, it is ensured that sealwort smooth surface, smooth, qualified sealwort is put into week Turning proceeds between wash after basket is weighed, and collects discarded object, seals and proceed to refuse depot after being weighed by discarded object;
Two, wash: the medicinal material after step one selects medicine is proceeded to wash district, is laid in wash basket, then uses with giant Circulating water is rinsed to without silt, scrubs clean the silt brush in a few surface out-of-flatness medicinal material crack, then will Medicinal material after washing proceeds to, in Turnround basket, be placed on draining rack;
Three, soak: weigh the yellow rice wine of clean medicinal material weight 3 times, be divided into many parts together with the sealwort cleaned through step 2, be respectively put into In multiple stainless steel casks, cover bung airtight, after soaking 48 hours, sealwort medicinal material in bucket is moved to Turnround basket;
Four, steaming the medicinal hebrs: be laid in food steamer by the sealwort after step 3 is soaked, overlays steamer successively by the food steamer installing sealwort On, food steamer stacks steamer cover on bonnet, opens steamer heating, starts timing, steaming the medicinal hebrs 12 after food steamer top layer starts to emit vapour Hour, after the time arrives, stopping heating, open steamer cover, the sealwort after steaming after temperature is down to below 50 DEG C takes out tiling Drip pan lets cool and receives after water to sealwort surface, be again laid in food steamer and repeat this step 3 time, altogether after steaming the medicinal hebrs four times, will Sealwort takes out and is laid in spreading for cooling 2 hours in stainless steel drip pan;
Five, medicine is dried: be placed in by the drip pan filling sealwort of spreading for cooling after step 4 steaming the medicinal hebrs on baking car, push in drying room, close and dry Door, controls baking temperature, at 45 DEG C~55 DEG C, to be dried material, starts timing after temperature reaches 45 DEG C, every 1 little Shi Kaiqi ventilation fan row's temperature 10 minutes, is dried after 24 hours and closes drying room, baking car is pushed out to spreading for cooling district and lets cool and i.e. obtain RHIZOMA POLYGONATI PREPARATA;
Six, packaging: according to packing instructions, the RHIZOMA POLYGONATI PREPARATA let cool in step 5 is dispensed.
The most according to claim 1, RHIZOMA POLYGONATI PREPARATA production technology, it is characterised in that in described step one, qualified sealwort weight is with useless The conjunction of gurry weight should be the 98%~100% of raw material weight.
RHIZOMA POLYGONATI PREPARATA production technology the most according to claim 1, it is characterised in that in described step 3, the concentration of yellow rice wine be 8 °~ 10°。
RHIZOMA POLYGONATI PREPARATA production technology the most according to claim 1, it is characterised in that in described step step 3, every part of sealwort weight control System is within 100kg.
The most according to claim 1, RHIZOMA POLYGONATI PREPARATA production technology, it is characterised in that in described step step 4, the sealwort in food steamer is thick Degree must not exceed 2/3rds of food steamer.
RHIZOMA POLYGONATI PREPARATA production technology the most according to claim 1, it is characterised in that in described step step 4, each steamer stacks Food steamer must not exceed 5 cages.
The most according to claim 1, RHIZOMA POLYGONATI PREPARATA production technology, it is characterised in that in described step step 4, drying during sealwort spreading for cooling Thickness in dish should be between 2cm~3cm.
The most according to claim 1, RHIZOMA POLYGONATI PREPARATA production technology, it is characterised in that in described step step 6, loading amount should be no less than mark The 97% of knowledge amount.
CN201610490765.7A 2016-06-29 2016-06-29 Production process for rhizoma polygonati preparata Pending CN105920331A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108619385A (en) * 2018-07-26 2018-10-09 贵州京源生态农业发展有限公司 A kind of preparation method that sealwort is dry
CN108770983A (en) * 2018-05-22 2018-11-09 陕西师范大学 A kind of production method of honey sealwort slice foodstuffs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102357200A (en) * 2011-11-15 2012-02-22 重庆市秀山红星中药材开发有限公司 Method for steaming manyflower solomonseal rhizome with rice wine under boosted pressure
CN103301311A (en) * 2013-05-31 2013-09-18 安徽源和堂药业股份有限公司 Preparation method of sealwort decoction piece
CN103432384A (en) * 2013-08-10 2013-12-11 田克力 Processing method of siberian solomoseal rhizome herbal pieces prepared for decoction

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102357200A (en) * 2011-11-15 2012-02-22 重庆市秀山红星中药材开发有限公司 Method for steaming manyflower solomonseal rhizome with rice wine under boosted pressure
CN103301311A (en) * 2013-05-31 2013-09-18 安徽源和堂药业股份有限公司 Preparation method of sealwort decoction piece
CN103432384A (en) * 2013-08-10 2013-12-11 田克力 Processing method of siberian solomoseal rhizome herbal pieces prepared for decoction

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108770983A (en) * 2018-05-22 2018-11-09 陕西师范大学 A kind of production method of honey sealwort slice foodstuffs
CN108619385A (en) * 2018-07-26 2018-10-09 贵州京源生态农业发展有限公司 A kind of preparation method that sealwort is dry

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