CN105911270A - Enzyme-linked immunometric meter - Google Patents
Enzyme-linked immunometric meter Download PDFInfo
- Publication number
- CN105911270A CN105911270A CN201610223841.8A CN201610223841A CN105911270A CN 105911270 A CN105911270 A CN 105911270A CN 201610223841 A CN201610223841 A CN 201610223841A CN 105911270 A CN105911270 A CN 105911270A
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- China
- Prior art keywords
- microplate reader
- controller
- power supply
- signal processor
- path system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
- G01N2021/0112—Apparatus in one mechanical, optical or electronic block
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- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The invention discloses an enzyme-linked immunometric meter, and belongs to the field of medical analysis apparatuses. The enzyme-linked immunometric meter comprises an enzyme-linked immunometric meter body, an optical path system, a sample cell, a signal processor, a controller, a power supply, a display screen and a button input device, the optical path system, the sample cell, the signal processor, the controller and the power supply are arranged in the enzyme-linked immunometric meter body, the display screen and the button input device are arranged on the surface of the enzyme-linked immunometric meter body, the optical path system is composed of a light source, a reflection mirror, a condensing mirror, an optical fiber beam and a filter wheel, the light source is an LED lamp group with different wavelengths, the condensing mirror and the reflection mirror are respectively fixedly arranged at the front side and the rear side of the light source, the tail end of the condensing mirror is connected with the optical fiber beam, the other side of the optical fiber beam is sequentially provided with the filter wheel, the sample cell and the signal processor, the power supply is connected with a power supply switching device, the power supply switching device is connected with the LED lamp group of the optical path system, the signal processor is connected with the controller, and the controller is respectively connected with the power supply switching device, the display screen and the button input device. The enzyme-linked immunometric meter has the advantages of energy saving, environmental protection, low use cost and long service life.
Description
Technical field
The present invention relates to medical analysis instrument field, be specially a kind of microplate reader.
Background technology
Microplate reader i.e. enzyme-linked immunosorbent assay instrument, it is that the instrumentation of elisa is also known as microwell plate detector, it is widely used in Clinical Laboratory, biological study, in food and research of agricultural science, microplate reader have also been obtained in reproductive health care field and is widely applied simultaneously, promotes the raising of healthy reproduction level.Optical system many employings Halogen light of current microplate reader or xenon lamp light source, coordinate monochromatic light generator that testing sample is analyzed test, owing to Halogen light and xenon lamp have one or more defects such as expensive, power consumption big, generation heat is many, add the use cost of microplate reader, if and the Halogen light heat radiation producing high temperature the most also can affect miscellaneous part, and then shortening the service life of microplate reader.
Summary of the invention
It is an object of the invention to provide a kind of microplate reader, it uses LED cold light source, has energy-conserving and environment-protective, feature with low cost, and can effectively extend the service life of microplate reader.
The technical problem to be solved realizes by the following technical solutions:
A kind of microplate reader, including microplate reader body, light path system, sample cell, signal processor, controller, power supply, display screen and press key input device, described light path system, sample cell, signal processor, controller and power supply are arranged at microplate reader, and this is internal, display screen and press key input device are arranged on microplate reader body surface, described light path system is by light source, illuminator, condenser lens, fibre-optic bundle and filter wheel composition, described light source is the LED group with different wave length, condenser lens and illuminator are separately fixed at side before and after light source, described condenser lens end connects fibre-optic bundle, it is sequentially provided with filter wheel at fibre-optic bundle opposite side, sample cell and signal processor.
Described power supply connects a power transfer device, this power transfer device is connected with light path system LED group and filter wheel respectively, for selecting and control the light on and off of light emitting diode and the rotation of filter wheel of LED group, described signal processor is connected with controller, and controller is connected with power transfer device, display screen and press key input device respectively.
Described filter wheel is made up of rotatable filter wheel body and optical filter, and described optical filter is fixed on filter wheel body, and number is 10 ~ 16.
In described LED group, the number of light emitting diode is consistent with optical filter number, and optical filter is corresponding with the light emitting diode in LED group respectively.
Described light emitting diode is visible light emitting diode or UV LED.
Described illuminator inwall is parabola.
Described microplate reader is the most internal is additionally provided with memorizer, and this memorizer is connected with controller, is provided with a data transmission interface on microplate reader body, and this data transmission interface is connected with memorizer.
The invention have the benefit that
(1) light path system of microplate reader uses LED group as light source, have that environmental protection, power consumption is low, length in service life and high brightness advantage low in calories, power transfer device can be controlled by controller, and then need the LED lighting corresponding wavelength to detect according to detection, while satisfied detection demand, reduce the use cost of microplate reader, extend its service life；
(2) condenser lens and illuminator are set in LED group front and back, scattered LED light line can be concentrated into the parallel rays of a branch of high brightness, promote the efficiency of light energy utilization and Detection results.
Accompanying drawing explanation
Fig. 1 is present configuration schematic diagram；
Fig. 2 is light path system schematic diagram of the present invention；
Fig. 3 is filter wheel structural representation of the present invention；
Fig. 4 is operation principle schematic diagram of the present invention；
Labelling in figure: 1-microplate reader body, 2-light path system, 21-light source, 22-illuminator, 23-condenser lens, 24-fibre-optic bundle, 25-filter wheel, 251-filter wheel body, 252-optical filter, 3-sample cell, 4-signal processor, 5-controller, 6-power supply, 7-display screen, 8-press key input device, 9-power transfer device, 10-memorizer, 11-data transmission interface.
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and be easy to understand with effect, the present invention is expanded on further below in conjunction with the accompanying drawings.
As shown in Fig. 1 ~ 4, a kind of microplate reader, including microplate reader body 1, light path system 2, sample cell 3, signal processor 4, controller 5, power supply 6, display screen 7 and press key input device 8, light path system 2, sample cell 3, signal processor 4, controller 5 and power supply 6 are arranged in microplate reader body 1, and display screen 7 and press key input device 8 are arranged on microplate reader body 1 surface.
Light path system 2 is made up of light source 21, illuminator 22, condenser lens 23, fibre-optic bundle 24 and filter wheel 25, light source 21 is the LED group with different wave length, condenser lens 23 and illuminator 22 are separately fixed at side before and after light source 21, condenser lens 23 end connects fibre-optic bundle 24, is sequentially provided with filter wheel 25, sample cell 3 and signal processor 4 at fibre-optic bundle 24 opposite side.
Power supply 6 connects a power transfer device 9, this power transfer device 9 is connected with LED group and the filter wheel 25 of light path system 2 respectively, for selecting and control light on and off and the rotation of filter wheel 25 of LED group light emitting diode, signal processor 4 is connected with controller 5, and controller 5 is connected with power transfer device 9, display screen 7 and press key input device 8 respectively.
Filter wheel 25 is made up of rotatable filter wheel body 251 and optical filter 252, and optical filter 252 is fixed on filter wheel body 251, and number is 10 ~ 16.
In LED group, the number of light emitting diode is consistent with optical filter 252 number, and optical filter 252 is corresponding with the light emitting diode in LED group respectively.
Light emitting diode is visible light emitting diode or UV LED.
Illuminator 22 inwall is parabola.
Being additionally provided with memorizer 10 in microplate reader body 1, this memorizer 10 is connected with controller 5, is provided with a data transmission interface 11 on microplate reader body 1, and this data transmission interface 11 is connected with memorizer 10.
During detection, liquid to be detected is placed in sample cell 3, button on operation press key input device 8, by press key input device 8, detection classification or parameter are pre-set, press key input device 8 by arrange information conveyance to controller 5, the light emitting diode of certain specific wavelength in LED group is lighted by controller 5 by power transfer device 9, and control filter wheel 25 rotate by power transfer device 9, corresponding optical filter 252 is made to align with fibre-optic bundle 24, start detection, signal processor 4 receives optical signal and is analyzed the absorbing state of light wave to testing result according to liquid to be detected, and the end product of detection is sent to controller 5, test result data is shown on display screen 7 and is saved in memorizer 10 by controller 5.
The ultimate principle of the present invention, principal character and advantage have more than been shown and described.Skilled person will appreciate that of the industry; the present invention is not restricted to the described embodiments; the principle that the present invention is simply described described in above-described embodiment and description; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements both fall within scope of the claimed invention.Claimed scope is defined by appending claims and equivalent thereof.
Claims (6)
1. a microplate reader, including microplate reader body, light path system, sample cell, signal processor, controller, power supply, display screen and press key input device, described light path system, sample cell, signal processor, controller and power supply are arranged at microplate reader, and this is internal, display screen and press key input device are arranged on microplate reader body surface, it is characterised in that:
Described light path system is made up of light source, illuminator, condenser lens, fibre-optic bundle and filter wheel, described light source is the LED group with different wave length, condenser lens and illuminator are separately fixed at side before and after light source, described condenser lens end connects fibre-optic bundle, is sequentially provided with filter wheel, sample cell and signal processor at fibre-optic bundle opposite side；
Described power supply connects a power transfer device, and this power transfer device is connected with light path system LED group and filter wheel respectively, and described signal processor is connected with controller, and controller is connected with power transfer device, display screen and press key input device respectively.
A kind of microplate reader, it is characterised in that: described filter wheel is made up of rotatable filter wheel body and optical filter, and described optical filter is fixed on filter wheel body, and number is 10 ~ 16.
A kind of microplate reader, it is characterised in that: in described LED group, the number of light emitting diode is consistent with optical filter number, and optical filter is corresponding with the light emitting diode in LED group respectively.
A kind of microplate reader, it is characterised in that: described light emitting diode is visible light emitting diode or UV LED.
5. according to a kind of microplate reader according to any one of claim 1 ~ 3, it is characterised in that: described illuminator inwall is parabola.
6. according to a kind of microplate reader according to any one of claim 1 ~ 3, it is characterized in that: described microplate reader is the most internal is additionally provided with memorizer, this memorizer is connected with controller, is provided with a data transmission interface on microplate reader body, and this data transmission interface is connected with memorizer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610223841.8A CN105911270A (en) | 2016-04-12 | 2016-04-12 | Enzyme-linked immunometric meter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610223841.8A CN105911270A (en) | 2016-04-12 | 2016-04-12 | Enzyme-linked immunometric meter |
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| Publication Number | Publication Date |
|---|---|
| CN105911270A true CN105911270A (en) | 2016-08-31 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610223841.8A Pending CN105911270A (en) | 2016-04-12 | 2016-04-12 | Enzyme-linked immunometric meter |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109387621A (en) * | 2017-08-02 | 2019-02-26 | 苏州百源基因技术有限公司 | A kind of detector and its application |
| CN112113919A (en) * | 2020-08-28 | 2020-12-22 | 菲仕医学设备（武汉）有限公司 | Enzyme-labeling instrument |
Citations (7)
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|---|---|---|---|---|
| CN1815196A (en) * | 2005-02-03 | 2006-08-09 | 三星电子株式会社 | Multi-channel fluorescence measuring optical system and multi-channel fluorescence sample analyzer |
| CN1924556A (en) * | 2005-08-29 | 2007-03-07 | 深圳雷杜生命科学股份有限公司 | Optical path system for clinical test analyzer |
| CN201045609Y (en) * | 2007-02-12 | 2008-04-09 | 深圳雷杜生命科学股份有限公司 | Light path device of enzyme labeling analytic instrument |
| CN203561580U (en) * | 2013-11-20 | 2014-04-23 | 武汉艾迪康医学检验所有限公司 | Optical system for medical examination microplate reader |
| CN203758905U (en) * | 2013-11-04 | 2014-08-06 | 叶金友 | Multi-light source light path system of channel of colorimetric pool and detection device |
| CN105300885A (en) * | 2015-12-02 | 2016-02-03 | 南京华欣分析仪器制造有限公司 | Optical path device of analytical instrument |
| CN205538988U (en) * | 2016-04-12 | 2016-08-31 | 成都恩普生医疗科技有限公司 | Energy -conserving ELIASA |
-
2016
- 2016-04-12 CN CN201610223841.8A patent/CN105911270A/en active Pending
Patent Citations (7)
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| CN1815196A (en) * | 2005-02-03 | 2006-08-09 | 三星电子株式会社 | Multi-channel fluorescence measuring optical system and multi-channel fluorescence sample analyzer |
| CN1924556A (en) * | 2005-08-29 | 2007-03-07 | 深圳雷杜生命科学股份有限公司 | Optical path system for clinical test analyzer |
| CN201045609Y (en) * | 2007-02-12 | 2008-04-09 | 深圳雷杜生命科学股份有限公司 | Light path device of enzyme labeling analytic instrument |
| CN203758905U (en) * | 2013-11-04 | 2014-08-06 | 叶金友 | Multi-light source light path system of channel of colorimetric pool and detection device |
| CN203561580U (en) * | 2013-11-20 | 2014-04-23 | 武汉艾迪康医学检验所有限公司 | Optical system for medical examination microplate reader |
| CN105300885A (en) * | 2015-12-02 | 2016-02-03 | 南京华欣分析仪器制造有限公司 | Optical path device of analytical instrument |
| CN205538988U (en) * | 2016-04-12 | 2016-08-31 | 成都恩普生医疗科技有限公司 | Energy -conserving ELIASA |
Non-Patent Citations (2)
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| 柯罗列娃等: "电影放映技术", 《电影放映技术》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109387621A (en) * | 2017-08-02 | 2019-02-26 | 苏州百源基因技术有限公司 | A kind of detector and its application |
| CN112113919A (en) * | 2020-08-28 | 2020-12-22 | 菲仕医学设备（武汉）有限公司 | Enzyme-labeling instrument |
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Application publication date: 20160831 |