CN105902853A - Traditional Chinese medicine preparation for preparing hypertension - Google Patents
Traditional Chinese medicine preparation for preparing hypertension Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for preparing hypertension. The traditional Chinese medicine preparation is prepared from the following components in parts by weight: 25 to 28 parts of spica prunellae, 18 to 20 parts of dried fructus crataegi, 15 to 19 parts of radix scutellariae, 19 to 22 parts of folium ginkgo, 17 to 20 parts of semen cassiae, 15 to 19 parts of flos chrysanthemi indici, 8 to 14 parts of herba dendrobii, 7 to 12 parts herba lophatheri, 8 to 13 parts of rhodiola, 8 to 14 parts of rhizoma gastrodiae, 7 to 10 parts of radix puerariae, 7 to 11 parts of cortex eucommiae, 9 to 14 parts of thin evodia leaf, 10 to 13 parts of ecklonia kurome okam, 9 to 12 parts of fructus ligustri lucidi, 8 to 14 parts of radix notoginseng and 3 to 6 parts of radix glycyrrhizae. The traditional Chinese medicine preparation disclosed by the invention has no toxic and side effects, and the effects in aspects of increasing the clinical effect, reducing blood pressure, improving clinical symptoms of a patient and the like are all superior to those of simple western medicine therapy. According to the traditional Chinese medicine preparation, through a monarch-minister-assistant-guide compatibility relation, the synergistic effect is obtained, and the blood pressure and the blood fat can be effectively reduced; meanwhile, other symptoms related to the hypertension can be relieved, and the clinical effect is good.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation treating hypertension.Belong to pharmaceutical technology field.
Background technology
Hypertension is the disease of lasting hyperpiesia, the diseases such as apoplexy, heart disease, hemangioma, renal failure can be caused, hypertension is that a kind of rising with arterial pressure is characterized, can be with the systemic disease of the functional or organic change of heart, blood vessel, brain and kidney and other organs.Hypertension is a kind of commonly encountered diseases, frequently-occurring disease, and its serious harm health affects the quality of life of people.
China is hypertension big country, and according to statistics, every 5 adults just have 1 people to be hyperpietic, and along with our people's living-pattern preservation, this impetus still has the trend of growth.
The general treatment method of hypertension is to take Western medicine at present, but often there is serious untoward reaction and side effect in Western medicine, easily bounce-back, need to take medicine throughout one's life, serious also can cause hypertensive heart disease, cerebrovas-cularaccident or apoplexy etc., reduce but symptom improves the problems such as inconspicuous it addition, there is also blood pressure.
Summary of the invention
It is an object of the invention to as overcoming above-mentioned the deficiencies in the prior art, it is provided that a kind of Chinese medicine preparation treating hypertension.
For achieving the above object, the present invention uses following technical proposals:
A kind of Chinese medicine preparation treating hypertension, it is made up of the component of following weight portion: Spica Prunellae 25～28 parts, Fructus Crataegi dry slice 18～20 parts, Radix Scutellariae 15～19 parts, Folium Ginkgo 19～22 parts, Semen Cassiae 17～20 parts, Flos Chrysanthemi Indici 15～19 parts, Herba Dendrobii 8～14 parts, Herba Lophatheri 7～12 parts, Radix Rhodiolae 8～13 parts, Rhizoma Gastrodiae 8～14 parts, Radix Puerariae 7～10 parts, the Cortex Eucommiae 7～11 parts, Foliumet Ramulus Evodiae 9～14 parts, Thallus Laminariae (Thallus Eckloniae) 10～13 parts, Fructus Ligustri Lucidi 9～12 parts, Radix Notoginseng 8～14 parts, Radix Glycyrrhizae 3～6 parts.
Preferably, it is made up of the component of following weight portion: Spica Prunellae 26～28 parts, Fructus Crataegi dry slice 18～19 parts, Radix Scutellariae 16～18 parts, Folium Ginkgo 20～22 parts, Semen Cassiae 18～19 parts, Flos Chrysanthemi Indici 16～18 parts, Herba Dendrobii 10～12 parts, Herba Lophatheri 8～11 parts, Radix Rhodiolae 10～12 parts, Rhizoma Gastrodiae 9～12 parts, Radix Puerariae 8～9 parts, the Cortex Eucommiae 8～10 parts, Foliumet Ramulus Evodiae 10～13 parts, Thallus Laminariae (Thallus Eckloniae) 11～12 parts, Fructus Ligustri Lucidi 10～12 parts, Radix Notoginseng 9～13 parts, Radix Glycyrrhizae 4～5 parts.
It is further preferred that be made up of the component of following weight portion: Spica Prunellae 27 parts, Fructus Crataegi dry slice 18 parts, Radix Scutellariae 17 parts, Folium Ginkgo 21 parts, Semen Cassiae 19 parts, Flos Chrysanthemi Indici 17 parts, Herba Dendrobii 11 parts, Herba Lophatheri 9 parts, Radix Rhodiolae 11 parts, 10 parts of Rhizoma Gastrodiae, Radix Puerariae 8 parts, the Cortex Eucommiae 10 parts, Foliumet Ramulus Evodiae 11 parts, Thallus Laminariae (Thallus Eckloniae) 12 parts, Fructus Ligustri Lucidi 11 parts, Radix Notoginseng 10 parts, 5 parts of Radix Glycyrrhizae.
Preferably, described Chinese medicine preparation is capsule, and its preparation method is:
(1) weigh each component of recipe ratio, add 3～the water of 5 times of weight, decoct 2～3 hours；
(2) filter, concentrated filtrate, dry, pulverize, obtain Chinese medicinal powder；
(3) by the starch mix homogeneously of Chinese medicinal powder and 1～5 times of weight, pelletize, be dried, granulate, encapsulated, obtain capsule.
It is further preferred that being dried as being spray-dried in step (2).
Beneficial effects of the present invention:
The Chinese medicine preparation of the present invention has no side effect, and is superior to simple western medicine treatment improving clinical efficacy, reduce blood pressure and improving the aspects such as patient clinical symptom.Hypertension increases except blood pressure, the highest with blood fat, it is also possible to cause kidney, vision damage etc., and hyperpietic often has the symptoms such as weak, thirsty, the headache of body void, treatment hypertension should take into account above-mentioned accompanied symptoms.
The pharmacological action of the present invention is as follows:
In the present invention, Spica Prunellae, sweet in the mouth, hardship pungent, micro-, there is effect of improving eyesight of relieving inflammation or internal heat, lowering blood pressure and blood fat and mass dissipating and swelling eliminating, as monarch drug, play primary treatment effect.
Fructus Crataegi dry slice, sour in the mouth, sweet, slightly warm in nature, treat hypertension, hyperlipidemia etc.；Radix Scutellariae, bitter, cold, heat clearing and damp drying, blood pressure lowering；Folium Ginkgo, sweet, bitter, puckery, flat, lowering blood pressure and blood fat, fall hyperlipidemia；Semen Cassiae, bitter in the mouth, sweet, salty, cold nature, for blood fat reducing improving eyesight, hypertension etc.；Flos Chrysanthemi Indici, is slightly cold, pungent, bitter, cures mainly hypertension etc.；Fructus Crataegi dry slice, Radix Scutellariae, Folium Ginkgo, Semen Cassiae and Flos Chrysanthemi Indici are as ministerial drug, auxiliary monarch drug treatment main symptom.
Herba Dendrobii, sweet in the mouth, cold nature, energy replenishing YIN and removing heat, reinforcing stomach reg fluid；Herba Lophatheri, sweet, cold, nontoxic, cure mainly only quench one's thirst, wind syndrome of head, dysphoria with smothery sensation etc. bitterly；Radix Rhodiolae, sweet, bitter, flat, there are benefiting QI for activating blood circulation, effect relievingd asthma of promoting blood circulation；Rhizoma Gastrodiae, property is pungent, warm, nontoxic, has effect of analgesia, qi-restoratives, and vascular nervous headache etc. is had significant curative effect；Radix Puerariae, sweet, pungent, cool, cure mainly quench one's thirst, high fever of the body, all poison of solution etc.；The Cortex Eucommiae, sweet in the mouth, warm in nature, there is balanced human's blood pressure, reduce body fat and recover the effects such as blood vessel elasticity；Foliumet Ramulus Evodiae, bitter, cold, there is effect of heat-clearing and toxic substances removing；Thallus Laminariae (Thallus Eckloniae), gas raw meat, salty in the mouth, acute renal decline etc. can be treated while lowering blood pressure and blood fat；Fructus Ligustri Lucidi, gas raw meat, salty in the mouth, there are the effects such as liver and kidney tonifying, item and clearind deficient heat；Radix Notoginseng, warm in nature, sweet in the mouth, micro-hardship, there is effect of supplementing QI for promoting the production of body fluid, subduing swelling and relieving pain；Herba Dendrobii, Herba Lophatheri, Radix Rhodiolae, Rhizoma Gastrodiae, Radix Puerariae, the Cortex Eucommiae, Foliumet Ramulus Evodiae, Thallus Laminariae (Thallus Eckloniae), Fructus Ligustri Lucidi and Radix Notoginseng, as adjuvant drug, coordinate monarch drug and ministerial drug treatment accompanied symptoms.
Radix Glycyrrhizae, sweet in the mouth is sweet, and property is gentle, is good at being in harmonious proportion the property of medicine, solves the poison of hundred medicines, as making medicine, guides all medicines to go directly diseased region.
The present invention compatibility relationship by monarch, synergism, effectively reduce blood pressure blood fat, alleviates other hypertension related symptoms simultaneously, and clinical effectiveness is good.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further elaborated, it should explanation, and its content, merely to explain the present invention, is not defined by the description below.
Embodiment 1:
A kind of Chinese medicine capsules treating hypertension of the present invention, it is made up of following components: Spica Prunellae 25kg, Fructus Crataegi dry slice 18kg, Radix Scutellariae 15kg, Folium Ginkgo 19kg, Semen Cassiae 17kg, Flos Chrysanthemi Indici 15kg, Herba Dendrobii 8kg, Herba Lophatheri 7kg, Radix Rhodiolae 8kg, Rhizoma Gastrodiae 8kg, Radix Puerariae 7kg, Cortex Eucommiae 7kg, Foliumet Ramulus Evodiae 9kg, Thallus Laminariae (Thallus Eckloniae) 10kg, Fructus Ligustri Lucidi 9kg, Radix Notoginseng 8kg, Radix Glycyrrhizae 3kg.
Its preparation method is:
(1) weigh each component of recipe ratio, add the water of 3 times of weight, decoct 2 hours；
(2) filter, concentrated filtrate, be spray-dried, pulverize, obtain Chinese medicinal powder；
(3) by Chinese medicinal powder with etc. the starch of weight mix homogeneously, pelletize, be dried, granulate, encapsulated (be distributed into 107Grain), obtain capsule.
Embodiment 2:
A kind of Chinese medicine capsules treating hypertension of the present invention, it is made up of following components: Spica Prunellae 28kg, Fructus Crataegi dry slice 20kg, Radix Scutellariae 19kg, Folium Ginkgo 22kg, Semen Cassiae 20kg, Flos Chrysanthemi Indici 19kg, Herba Dendrobii 14kg, Herba Lophatheri 12kg, Radix Rhodiolae 13kg, Rhizoma Gastrodiae 14kg, Radix Puerariae 10kg, Cortex Eucommiae 11kg, Foliumet Ramulus Evodiae 14kg, Thallus Laminariae (Thallus Eckloniae) 13kg, Fructus Ligustri Lucidi 12kg, Radix Notoginseng 14kg, Radix Glycyrrhizae 6kg.
Its preparation method is:
(1) weigh each component of recipe ratio, add the water of 5 times of weight, decoct 3 hours；
(2) filter, concentrated filtrate, be spray-dried, pulverize, obtain Chinese medicinal powder；
(3) by the starch mix homogeneously of Chinese medicinal powder and 5 times of weight, pelletize, be dried, granulate, encapsulated (be distributed into 107Grain), obtain capsule.
Embodiment 3:
A kind of Chinese medicine capsules treating hypertension of the present invention, it is made up of following components: Spica Prunellae 26kg, Fructus Crataegi dry slice 18kg, Radix Scutellariae 16kg, Folium Ginkgo 20kg, Semen Cassiae 18kg, Flos Chrysanthemi Indici 16kg, Herba Dendrobii 10kg, Herba Lophatheri 8kg, Radix Rhodiolae 10kg, Rhizoma Gastrodiae 9kg, Radix Puerariae 8kg, Cortex Eucommiae 8kg, Foliumet Ramulus Evodiae 10kg, Thallus Laminariae (Thallus Eckloniae) 11kg, Fructus Ligustri Lucidi 10kg, Radix Notoginseng 9kg, Radix Glycyrrhizae 4kg.
Its preparation method is:
(1) weigh each component of recipe ratio, add the water of 4 times of weight, decoct 2 hours；
(2) filter, concentrated filtrate, be spray-dried, pulverize, obtain Chinese medicinal powder；
(3) by the starch mix homogeneously of Chinese medicinal powder and 3 times of weight, pelletize, be dried, granulate, encapsulated (be distributed into 107Grain), obtain capsule.
Embodiment 4:
A kind of Chinese medicine capsules treating hypertension of the present invention, it is made up of following components: Spica Prunellae 28kg, Fructus Crataegi dry slice 19kg, Radix Scutellariae 18kg, Folium Ginkgo 22kg, Semen Cassiae 19kg, Flos Chrysanthemi Indici 18kg, Herba Dendrobii 12kg, Herba Lophatheri 11kg, Radix Rhodiolae 12kg, Rhizoma Gastrodiae 12kg, Radix Puerariae 9kg, Cortex Eucommiae 10kg, Foliumet Ramulus Evodiae 13kg, Thallus Laminariae (Thallus Eckloniae) 12kg, Fructus Ligustri Lucidi 12kg, Radix Notoginseng 13kg, Radix Glycyrrhizae 5kg.
Its preparation method is:
(1) weigh each component of recipe ratio, add the water of 4 times of weight, decoct 3 hours；
(2) filter, concentrated filtrate, be spray-dried, pulverize, obtain Chinese medicinal powder；
(3) by the starch mix homogeneously of Chinese medicinal powder and 3 times of weight, pelletize, be dried, granulate, encapsulated (be distributed into 107Grain), obtain capsule.
Embodiment 5:
A kind of Chinese medicine capsules treating hypertension of the present invention, it is made up of following components: Spica Prunellae 27kg, Fructus Crataegi dry slice 18kg, Radix Scutellariae 17kg, Folium Ginkgo 21kg, Semen Cassiae 19kg, Flos Chrysanthemi Indici 17kg, Herba Dendrobii 11kg, Herba Lophatheri 9kg, Radix Rhodiolae 11kg, Rhizoma Gastrodiae 10kg, Radix Puerariae 8kg, Cortex Eucommiae 10kg, Foliumet Ramulus Evodiae 11kg, Thallus Laminariae (Thallus Eckloniae) 12kg, Fructus Ligustri Lucidi 11kg, Radix Notoginseng 10kg, Radix Glycyrrhizae 5kg.
Its preparation method is:
(1) weigh each component of recipe ratio, add the water of 3 times of weight, decoct 3 hours；
(2) filter, concentrated filtrate, be spray-dried, pulverize, obtain Chinese medicinal powder；
(3) by the starch mix homogeneously of Chinese medicinal powder and 4 times of weight, pelletize, be dried, granulate, encapsulated (be distributed into 107Grain), obtain capsule.
The using method of the present invention is, takes 2 early morning every day, 1 time on the 1st, within seven days, is a course for the treatment of.
Test example
1. diagnosis basis
According to World Health Organization (WHO)/International Society of Hypertension (WHO/ISH)
The new Treatment Guidelines for Hypertension promulgated is determined, and i.e. under not taking antihypertensive drugs, shrinks pressure >=18.7kPa (140mmHg)
And (or) diastolic pressure >=12.0kPa (90mmHg), certainly unless blood pressure extremely raises and merges medical condition relevant (end target organ damage eventually), can not be according only to a blood pressure measurement diagnosis primary disease.After pressure measurement first finds that blood pressure raises, should at least measure twice different occasion to determine whether blood pressure raises.
2. criterion of therapeutical effect:
2.1 cure: contraction pressure≤
18.7kPa (140mmHg) and diastolic pressure≤
12.0kPa(90mmHg)。
2.2 is effective: contraction pressure >=
18.7kPa (140mmHg) and (or) diastolic pressure >=
12.0kPa (90mmHg), but blood pressure decreases.
2.3 is invalid: blood pressure is unchanged, other severity of symptoms.
3. model case:
(1) Lee, man, 55 years old, suffer from hypertension 26 years, long-term is about 160mmHg by Western medicine maintenance in examination in hospital contraction pressure, and diastolic pressure is 110mmHg, with the empty weak and hyperlipidemia of body.After taking one course for the treatment of of medicine of the present invention, realizing that effect is fine, complication substantially alleviates, in high spirits, rate and blood-lipid decreased, continues thereafter with and takes 2 courses for the treatment of, and after taking medicine, blood pressure recovers normal completely, reaches criterion of cure, after taken again a course for the treatment of and consolidated, drug withdrawal so far, not bounce-back.
(2) field, female, 65 years old, suffer from hypertension 28 years, dizzy headache recurrent exerbation, tinnitus, irascible temperament, the most thirsty, time the highest, blood pressure is 210/100mmHg, irregularly takes western medicine, take the capsule of the present invention after three days blood pressure reduce to 139/90mmHg, fluctuate in 138～145/90mmHg scopes ever since, dizzy headache, xerostomia and bitter, the symptom such as being irritable and irascible substantially alleviates, take medicine after three courses for the treatment of, symptom disappears substantially, and check all goes well, without any untoward reaction in medication period, without recurrence, thoroughly cure.
(3) journey, man, 41 years old, minimal invasive treatment is the most irregular, insobriety, kidney disease, then hypertension is caused, blood pressure is up to 170/135mmHg, and the normal phase takes Western medicine, and blood pressure is declined slightly, but the untoward reaction such as weak all over, hypomnesis occur, the capsule blood pressure two days later taking the present invention effectively declines, and after the course for the treatment of, blood pressure stabilization is at 125/90mmHg
Hereinafter, various complication are also wholly absent, drug withdrawal, without recurrence.
Although the above-mentioned detailed description of the invention to the present invention is described; but not limiting the scope of the invention; on the basis of technical scheme, those skilled in the art need not to pay various amendments or deformation that creative work can make still within protection scope of the present invention.
Claims (5)
1. the Chinese medicine preparation treating hypertension, it is characterised in that it is made up of the component of following weight portion: Spica Prunellae 25～28 parts, Fructus Crataegi dry slice 18～20 parts, Radix Scutellariae 15～19 parts, Folium Ginkgo 19～22 parts, Semen Cassiae 17～20 parts, Flos Chrysanthemi Indici 15～19 parts, Herba Dendrobii 8～14 parts, Herba Lophatheri 7～12 parts, Radix Rhodiolae 8～13 parts, Rhizoma Gastrodiae 8～14 parts, Radix Puerariae 7～10 parts, the Cortex Eucommiae 7～11 parts, Foliumet Ramulus Evodiae 9～14 parts, Thallus Laminariae (Thallus Eckloniae) 10～13 parts, Fructus Ligustri Lucidi 9～12 parts, Radix Notoginseng 8～14 parts, Radix Glycyrrhizae 3～6 parts.
Chinese medicine preparation the most according to claim 1, it is characterized in that, it is made up of the component of following weight portion: Spica Prunellae 26～28 parts, Fructus Crataegi dry slice 18～19 parts, Radix Scutellariae 16～18 parts, Folium Ginkgo 20～22 parts, Semen Cassiae 18～19 parts, Flos Chrysanthemi Indici 16～18 parts, Herba Dendrobii 10～12 parts, Herba Lophatheri 8～11 parts, Radix Rhodiolae 10～12 parts, Rhizoma Gastrodiae 9～12 parts, Radix Puerariae 8～9 parts, the Cortex Eucommiae 8～10 parts, Foliumet Ramulus Evodiae 10～13 parts, Thallus Laminariae (Thallus Eckloniae) 11～12 parts, Fructus Ligustri Lucidi 10～12 parts, Radix Notoginseng 9～13 parts, Radix Glycyrrhizae 4～5 parts.
Chinese medicine preparation the most according to claim 1, it is characterised in that be made up of the component of following weight portion: Spica Prunellae 27 parts, Fructus Crataegi dry slice 18 parts, Radix Scutellariae 17 parts, Folium Ginkgo 21 parts, Semen Cassiae 19 parts, Flos Chrysanthemi Indici 17 parts, Herba Dendrobii 11 parts, Herba Lophatheri 9 parts, Radix Rhodiolae 11 parts, 10 parts of Rhizoma Gastrodiae, Radix Puerariae 8 parts, the Cortex Eucommiae 10 parts, Foliumet Ramulus Evodiae 11 parts, Thallus Laminariae (Thallus Eckloniae) 12 parts, Fructus Ligustri Lucidi 11 parts, Radix Notoginseng 10 parts, 5 parts of Radix Glycyrrhizae.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is capsule, its preparation method is:
(1) weigh each component of recipe ratio, add 3～the water of 5 times of weight, decoct 2～3 hours；
(2) filter, concentrated filtrate, dry, pulverize, obtain Chinese medicinal powder；
(3) by the starch mix homogeneously of Chinese medicinal powder and 1～5 times of weight, pelletize, be dried, granulate, encapsulated, obtain capsule.
Chinese medicine preparation the most according to claim 4, it is characterised in that being dried as being spray-dried in step (2).
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106566753A (en) * | 2016-11-04 | 2017-04-19 | 孝感麻糖米酒有限责任公司 | Blood pressure lowering rice wine and preparation method thereof |
| CN114403434A (en) * | 2022-01-12 | 2022-04-29 | 山东贝隆杜仲生物工程有限公司 | Composition with blood pressure lowering effect and prepared from eucommia ulmoides as raw material and preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129817A (en) * | 2007-09-26 | 2008-02-27 | 王福春 | Chinese medicine formulation for treating hypertension and method of producing the same |
| CN103751566A (en) * | 2013-12-24 | 2014-04-30 | 申天顺 | Traditional Chinese medicinal prescription for treating hypertension |
| CN104815192A (en) * | 2015-04-30 | 2015-08-05 | 青岛市市立医院 | Pharmaceutical composition for treating hypertension and application of pharmaceutical composition |
| CN105055915A (en) * | 2015-07-17 | 2015-11-18 | 山东方健制药有限公司 | Traditional Chinese medicine composition for treating hypertension |
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2016
- 2016-05-17 CN CN201610324522.6A patent/CN105902853A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129817A (en) * | 2007-09-26 | 2008-02-27 | 王福春 | Chinese medicine formulation for treating hypertension and method of producing the same |
| CN103751566A (en) * | 2013-12-24 | 2014-04-30 | 申天顺 | Traditional Chinese medicinal prescription for treating hypertension |
| CN104815192A (en) * | 2015-04-30 | 2015-08-05 | 青岛市市立医院 | Pharmaceutical composition for treating hypertension and application of pharmaceutical composition |
| CN105055915A (en) * | 2015-07-17 | 2015-11-18 | 山东方健制药有限公司 | Traditional Chinese medicine composition for treating hypertension |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106566753A (en) * | 2016-11-04 | 2017-04-19 | 孝感麻糖米酒有限责任公司 | Blood pressure lowering rice wine and preparation method thereof |
| CN114403434A (en) * | 2022-01-12 | 2022-04-29 | 山东贝隆杜仲生物工程有限公司 | Composition with blood pressure lowering effect and prepared from eucommia ulmoides as raw material and preparation method |
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Application publication date: 20160831 |