CN103961677A - Traditional Chinese medicine mixture for treating arrhythmia - Google Patents

Abstract

The invention discloses a traditional Chinese medicine mixture for treating arrhythmia. The traditional Chinese medicine mixture for treating arrhythmia is characterized by being prepared ftrom the following traditional Chinese medicine raw materials in parts by weight: 30 parts of cinnamon, 12 parts of cassia twig, 30 parts of oyster, 10 parts of radix paeoniae rubra, 30 parts of astragalus membranaceus, 20 parts of jujube, 30 parts of fossil fragments, 6 parts of ginger, 15 parts of monkshood, 6 parts of liquorice, 20 parts of poria cocos and 18 parts of rhizoma pinelliae preparata. The traditional Chinese medicine mixture for treating arrhythmia has the advantages of quick drug release, quick effect, less toxic and side effects, convenience in taking and the like.

Description

A kind ofly treat ARR Traditional Chinese drug mixture

Technical field:

The present invention relates to Chinese medicine technical field, is exactly specifically a kind of ARR Traditional Chinese drug mixture for the treatment of.

Background technology:

Arrhythmia refers to: the rhythm of the heart is beating within normal range not.Heart rate, at 160～220 beats/min, is often called paroxysmal tachycardia.Heart rate, lower than 60 beats/min of persons (generally more than 40 beats/min), is called sinus bradycardia.Heart rate, lower than 40 beats/min, should consider to have atrioventricular block.The rhythm of the heart is too fast surpasses 160 beats/min, or lower than 40 beats/min, is more common in greatly heart disease patient, the normal had palpitation of patient, the symptom such as uncomfortable in chest, pareordia is uncomfortable.Now larger for ARR treatment difficulty, to patient, caused larger misery.

Summary of the invention:

The present invention is exactly in order to make up the deficiencies in the prior art, provides a kind of have for ARR treatment to extensive patients and medical personnel, and release is fast, and effective fast, toxic and side effects is little, and the Traditional Chinese drug mixture of taking convenience.

The invention provides following technical scheme:

Treat an ARR Traditional Chinese drug mixture, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: Cortex Cinnamomi 20-50 part, Ramulus Cinnamomi 10-20 part, Concha Ostreae 20-50 part, Radix Paeoniae Rubra 5-15 part, Radix Astragali 20-50 part, Fructus Jujubae 10-30 part, Os Draconis 20-50 part, Rhizoma Zingiberis Recens 3-10 part, Radix Aconiti Lateralis Preparata 5-20 part, Radix Glycyrrhizae 3-10 part, Poria 10-30 part, Rhizoma Pinelliae 10-30 part.

Optimization formula is:

30 parts of Cortex Cinnamomis, 12 parts of Ramulus Cinnamomi, 30 parts of Concha Ostreaes, 10 parts of Radix Paeoniae Rubra, 30 parts of the Radixs Astragali, 20 parts, Fructus Jujubae, 30 parts of Os Draconis, 6 parts, Rhizoma Zingiberis Recens, 15 parts of Radix Aconiti Lateralis Preparatas, 6 parts, Radix Glycyrrhizae, 20 parts, Poria, 18 parts of Rhizoma Pinelliae.

Preparation method:

Component takes described various raw material of Chinese medicine by weight, remove impurity is cleaned, section, add again 5 times of water gagings, big fire is boiled 30 minutes, little fire decocts 1 hour, collects filtrate for later use, and filtering residue adds 2 times of water gagings again and decocts 2 hours, waste merges filtrate twice, filter, then through concentrated, dry, pulverizing, cross 200 mesh sieves and make extract particles agent, by formula proportion, take again the extraction granule of each herbal medicine, mixing and stirring, incapsulates after sterilizing and makes capsule preparations, and every capsules explosive payload is 3 grams.

The explanation of taking medicine:

Morning, noon and afternoon every day take medicine once, each 6-12 gram, and taking medicine continuously two weeks is 1 course for the treatment of.

Below the detailed description that forms various raw material of Chinese medicine of the present invention:

Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.There is complement sun, warming the spleen and stomach, removing accumulated cold, the effects such as promoting blood circulation.Be usually used in treating decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, the diseases such as heat in the upper and cold in the lower.Zoopery shows: Radix Aconiti Lateralis Preparata, Cortex Cinnamomi compound recipe have hypotensive effect to adrenal cortex Hypertensive Rats.

Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.GUIXIN, lung, urinary bladder channel.There is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat effects such as gas of spining.Be usually used in anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, the diseases such as renal mass.Ramulus Cinnamomi ethanol extract can suppress escherichia coli, bacillus subtilis and staphylococcus aureus in vitro, and valid density is 25 mg/ml or following; Staphylococcus albus, dysentery bacterium, Typhoid and paratyphoid first bacillus, streptococcus pneumoniae, aerobacteria, Bacillus proteus, anthrax bacillus, Salmonella enteritidis, vibrio cholera etc. are also had to inhibitory action.

Concha Ostreae: salty in the mouth, cold nature.Return liver, gallbladder, kidney channel.There is tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, the effects such as hard masses softening and resolving.Be usually used in treatment palpitation with fear insomnia, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, the diseases such as stomachache acid regurgitation.This product also has and has convergence, calmness, removing toxic substances, analgesic effect; The acidic extraction thing of Concha Ostreae to poliovirus inhibitory action, makes the effects such as Mus mortality rate reduction that infect in live body.

Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.There is clearing away heat and cooling blood, the effects such as eliminating stasis to stop pain.Be usually used in treating maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, the diseases such as carbuncle skin infection.This product also has antithrombotic formation, antiplatelet aggregation, blood fat reducing and arteriosclerosis, acute myocardial ischemia is had to the effects such as obvious protection.

The Radix Astragali: sweet in the mouth, warm in nature.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effects such as expelling pus and promoting granulation.Be usually used in treating the deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, the diseases such as diabetes.This product also has can strengthen normal heart contraction, and the heart of exhaustion is had to cardiotonic; Can make tubular blood vessel and renal blood vessels expansion, and make the expansion of whole body peripheral vessel, skin circulation is freely contained, and makes hyperpietic's blood pressure drops; Calm; Blood sugar lowering; Dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. are all had to the effects such as inhibitory action.

Fructus Jujubae: sweet in the mouth, warm in nature.Return spleen, stomach warp.There is invigorating the spleen and replenishing QI, the effects such as nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, the diseases such as woman hysteria.This product also have antitumor. resisting I-type allergic reaction, IgE antibody is produced have specific inhibitory effect, to nervus centralis have inhibitory action, put on weight, the effect such as muscle strength reinforcing effect.

Os Draconis: sweet in the mouth, puckery, property is flat.There is calmness, arresting sweating arresting seminal emission, the effects such as promoting tissue regeneration and ulcer healing.Be usually used in treating neurasthenia, cardiopalmus, insomnia, dreaminess, spontaneous perspiration, night sweat, seminal emission, the enuresis, metrorrhagia, is with inferior disease.Research shows: this product also has promotion blood clotting, reduces Vascular Permeability and suppresses the effects such as skeletal muscle excitement.

Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature.Return lung, spleen, stomach warp.There is the cold expelling of inducing sweat, warming middle-JIAO to arrest vomiting, the effects such as preventing phlegm from forming and stopping coughing.Be usually used in treating anemofrigid cold, gastrofrigid vomiting, the diseases such as cold-phlegm cough.Experiment shows: normal person's chewing Rhizoma Zingiberis Recens 1g(does not swallow), can make the systolic pressure 11.2mm mercury column that on average raises, diastolic pressure rising 14mm mercury column, to pulse frequency without significant impact.Alcoholic extract has excitation to anesthetized cat vasomotor center and respiratory center, and heart is also had to direct excitation.

Radix Aconiti Lateralis Preparata: acrid in the mouth, sweet, extremely hot in nature; Poisonous.GUIXIN, kidney, spleen channel.There is recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by effects such as wind-cold damp pathogens.Be usually used in treating YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the diseases such as arthralgia due to cold-dampnes.Research shows: this product also has heart tonifying and boosting, and contained demethylcoclaurine energy cardioacceleration in this product is improved effect to experimental slow arrhythmia.Clinical observation has also confirmed that demethylcoclaurine has obvious therapeutical effect to slow arrhythmia.After intravenous injection, patient's heart rate all has increase in various degree, and sinus bradycardia returns to normal level, and sino atrial block and interface Atrioventricular Conduction improve, thereby conduction block are alleviated or disappear, and its mechanism is mainly and shortens A-H interval.Test and also show, demethylcoclaurine is similar to the affinity of B-adrenergic receptor with isoproterenol, but intrinsic activity is significantly less than isoproterenol.Thereby directly prove that demethylcoclaurine is B-adrenergic receptor partial agonist.Trachea beta 2-receptor is also had to obvious agonism, and this effect is than directly exciting myocardium B1-receptor is strong.For explaining that the recuperating depleted YANG and rescuing the patient from collapse of Radix Aconiti Lateralis Preparata provides half-proof.

Radix Glycyrrhizae: sweet in the mouth, property is flat.GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in treating weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.This product can be separated the effects such as Radix Aconiti Lateralis Preparata poison and the effect of adrenocortical hormone sample.

Poria: sweet in the mouth, light, property is flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, the effects such as spleen invigorating mind calming.Be usually used in treating edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia waits disease.This product does not find that Poria has bacteriostasis in vitro, and ethanol extraction is external can kill leptospira; Reduce blood glucose, tincture, preserved material can suppress Bufo siccus isolated heart, and ether or ethanol extraction can make the heart shrink the effects such as reinforcement.

Rhizoma Pinelliae: acrid in the mouth, warm in nature; Poisonous.Return spleen, stomach, lung meridian.There is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the diseases such as dissolving lump and resolving mass.Be usually used in treating abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.This product is to tryptic inhibitory action; Blood pressure lowering; Adrenal cortex function is had to the effects such as slight stimulation and short cell division.

Clinical drug result of use of the present invention is obvious, have that evident in efficacy, short treating period, amount of consumption of drugs are few, at the bottom of cost, easy to use, be beneficial to the advantages such as absorption, greatly improved patient's health status.

The specific embodiment:

Embodiment 1:

Treat an ARR Traditional Chinese drug mixture, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 30 parts of Cortex Cinnamomis, 12 parts of Ramulus Cinnamomi, 30 parts of Concha Ostreaes, 10 parts of Radix Paeoniae Rubra, 30 parts of the Radixs Astragali, 20 parts, Fructus Jujubae, 30 parts of Os Draconis, 6 parts, Rhizoma Zingiberis Recens, 15 parts of Radix Aconiti Lateralis Preparatas, 6 parts, Radix Glycyrrhizae, 20 parts, Poria, 18 parts of Rhizoma Pinelliae.

Preparation method:

Component takes described various raw material of Chinese medicine by weight, remove impurity is cleaned, section, add again 5 times of water gagings, big fire is boiled 30 minutes, little fire decocts 1 hour, collects filtrate for later use, and filtering residue adds 2 times of water gagings again and decocts 2 hours, waste merges filtrate twice, filter, then through concentrated, dry, pulverizing, cross 200 mesh sieves and make extract particles agent, by formula proportion, take again the extraction granule of each herbal medicine, mixing and stirring, incapsulates after sterilizing and makes capsule preparations, and every capsules explosive payload is 3 grams.

Embodiment 2:

Treat an ARR Traditional Chinese drug mixture, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 50 parts of Cortex Cinnamomis, 20 parts of Ramulus Cinnamomi, 50 parts of Concha Ostreaes, 15 parts of Radix Paeoniae Rubra, 45 parts of the Radixs Astragali, 30 parts, Fructus Jujubae, 40 parts of Os Draconis, 8 parts, Rhizoma Zingiberis Recens, 15 parts of Radix Aconiti Lateralis Preparatas, 10 parts, Radix Glycyrrhizae, 30 parts, Poria, 20 parts of Rhizoma Pinelliae.

Preparation method:

Component takes described various raw material of Chinese medicine by weight, remove impurity is cleaned, section, add again 5 times of water gagings, big fire is boiled 30 minutes, little fire decocts 1 hour, collects filtrate for later use, and filtering residue adds 2 times of water gagings again and decocts 2 hours, waste merges filtrate twice, filter, then through concentrated, dry, pulverizing, cross 200 mesh sieves and make extract particles agent, by formula proportion, take again the extraction granule of each herbal medicine, mixing and stirring, incapsulates after sterilizing and makes capsule preparations, and every capsules explosive payload is 3 grams.

Embodiment 3:

Treat an ARR Traditional Chinese drug mixture, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 20 parts of Cortex Cinnamomis, 10 parts of Ramulus Cinnamomi, 20 parts of Concha Ostreaes, 5 parts of Radix Paeoniae Rubra, 20 parts of the Radixs Astragali, 10 parts, Fructus Jujubae, 20 parts of Os Draconis, 3 parts, Rhizoma Zingiberis Recens, 5 parts of Radix Aconiti Lateralis Preparatas, 3 parts, Radix Glycyrrhizae, 10 parts, Poria, 10 parts of Rhizoma Pinelliae.

Preparation method:

Component takes described various raw material of Chinese medicine by weight, remove impurity is cleaned, section, add again 5 times of water gagings, big fire is boiled 30 minutes, little fire decocts 1 hour, collects filtrate for later use, and filtering residue adds 2 times of water gagings again and decocts 2 hours, waste merges filtrate twice, filter, then through concentrated, dry, pulverizing, cross 200 mesh sieves and make extract particles agent, by formula proportion, take again the extraction granule of each herbal medicine, mixing and stirring, incapsulates after sterilizing and makes capsule preparations, and every capsules explosive payload is 3 grams.

For showing that medicine of the present invention is for the various ARR therapeutic effect for the treatment of, through clinical as follows: use the prepared Traditional Chinese drug mixture of embodiment 1 to treat all kinds of arrhythmia patient 45 examples, cure 25 examples, effective 13 examples, effective 4 examples, invalid 3 examples, effective percentage reaches 90%.

Model case:

1, patient Zhao so-and-so, man, 62 years old.Except suffering from hypertension, the regular profound dizzy disease taking medicine and showing effect occasionally, it is hale and hearty that health can be said to be, and there is no other major diseases.But start the year before, fall in a swoon suddenly, each approximately continue the several seconds and just naturally wake up, had palpitation and symptom uncomfortable in chest often, occur twice or thrice every month, at hospital diagnosis, is arrhythmia.Take after two weeks of the present invention, feel happy from head to foot, uncomfortable in chest alleviating, successful.Take continuously three months, cardiopalmus, transference cure uncomfortable in chest, do not faint yet again.After continue to strengthen and take two months again.Follow up a case by regular visits to 1 year, do not recur again.

2, patient Liu so-and-so, female, 51 years old.Patient is even, and to cough companion nervous, uncomfortable in chest, weak, arrhythmia 14 days, 130 beats/min of hearts rate, take the Chinese medicinal capsule of the embodiment of the present invention 3 preparations, after one month, stable disease, after adhere to treating three months, various transference cures, comprehensive review, indices is all normal.

3, patient Zhang, man, 48 years old.Patient finds that when the prime of life heart beating is usually too fast, is diagnosed as arrhythmia, busy at that time, not conscientiously treatment, and aggravation, faints twice when serious recently.Under friend introduces, take the present invention real, after one month, heartbeating recovery is normal, and effect is remarkable.After consolidate again and taken three months.Check indices is normal.Follow up a case by regular visits to 2 years, do not occur fainting.

4, patient king so-and-so, female, 51 years old.Patient was diagnosed as arrhythmia before 2 years, had sensation uncomfortable in chest.Ate after Western medicine, took a turn for the better to some extent.But never radical cure, occurs again that afternoon nap is dizzy after waking up recently.Take the present invention, after one month, heartbeating recovery is normal, and various symptoms disappear thereupon.She consolidates and takes two months again afterwards.After drug withdrawal, do not reaccess so far.

5, grandson patient so-and-so, man, 46 years old.Start to occur that regular heart beating intermittently, often occurs in about at 11 o'clock in the morning and after falling asleep evening in May, 2009, during outbreak, with breast nebula and nervous sense, thereby it is not peaceful to sleep night, and spirit is poor.Took once Western medicine, treatment by Chinese herbs, DeGrain.Look into: dim complexion, spiritlessness and weakness, inappetence, nervous heart beating, pale and tender tongue are partially dry, thin white fur of tongue, and sublingual vein is purple dark.Take the present invention after one month, various symptoms obviously alleviate, and take after three months, return to one's perfect health, and sleep is normal.Follow up a case by regular visits to so far, not recurrence again.

6, patient Jiang, man, 56 years old.The first visit time: in May, 2010.Diagnosis: prominent sense cardiopalmus when patient climbs the mountain, the motive is short, uncomfortable in chest, slightly alleviates after having a rest approximately one hour.But after this conscious muscle power day by day declines, a little activity feel breathe hard, uncomfortable in chest, night suppresses awake sometimes.Without precordial pain.At hospital diagnosis, be arrhythmia, take Western medicine curative effect bad.After take the Chinese medicinal capsule of the embodiment of the present invention 5 preparation, after one month, cardiopalmus, uncomfortable in chest alleviate a lot, after take again two months, various transference cures, muscle power and energy is day by day recovery also.For preventing recurrence, consolidate and take three months again.Follow up a case by regular visits to so far, not recurrence again.

7, Chen, man, 52 years old.Patient before 6 years, occurred palpitating speed, nervous with uncomfortable in chest, without chest pain, continue can turnaround voluntarily for 20～30 minutes, when asymptomatic, look into normal ECG.Annual outbreak 4～5 times.Took some Chinese and western drugses, still recurrence.Under kith and kin introduce, take the present invention's drug withdrawal after three months, do not take again other medicines, to observe 3 years, above-mentioned symptom is recurrence again not.

Claims (2)

1. the ARR Traditional Chinese drug mixture for the treatment of, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: Cortex Cinnamomi 20-50 part, Ramulus Cinnamomi 10-20 part, Concha Ostreae 20-50 part, Radix Paeoniae Rubra 5-15 part, Radix Astragali 20-50 part, Fructus Jujubae 10-30 part, Os Draconis 20-50 part, Rhizoma Zingiberis Recens 3-10 part, Radix Aconiti Lateralis Preparata 5-20 part, Radix Glycyrrhizae 3-10 part, Poria 10-30 part, Rhizoma Pinelliae 10-30 part.

2. according to a kind of described in claim 1, treat ARR Traditional Chinese drug mixture, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 30 parts of Cortex Cinnamomis, 12 parts of Ramulus Cinnamomi, 30 parts of Concha Ostreaes, 10 parts of Radix Paeoniae Rubra, 30 parts of the Radixs Astragali, 20 parts, Fructus Jujubae, 30 parts of Os Draconis, 6 parts, Rhizoma Zingiberis Recens, 15 parts of Radix Aconiti Lateralis Preparatas, 6 parts, Radix Glycyrrhizae, 20 parts, Poria, 18 parts of Rhizoma Pinelliae.