CN105902429A - Plant type anti-bacterial foaming hand sanitizer - Google Patents

Plant type anti-bacterial foaming hand sanitizer Download PDF

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Publication number
CN105902429A
CN105902429A CN201610303390.9A CN201610303390A CN105902429A CN 105902429 A CN105902429 A CN 105902429A CN 201610303390 A CN201610303390 A CN 201610303390A CN 105902429 A CN105902429 A CN 105902429A
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Prior art keywords
parts
ethylene glycol
sodium alginate
citric acid
glycerine
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CN201610303390.9A
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CN105902429B (en
Inventor
严敬华
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Zhejiang shiweikang biomedical materials Co.,Ltd.
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Hangzhou Oxyaction Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/733Alginic acid; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

The invention discloses a plant type anti-bacterial foaming hand sanitizer. The hand sanitizer is prepared from the following raw materials in parts by weight: 40-50 parts of plant extract, 55-65 parts of water, 10-20 parts of glycerol, 3-5 parts of citric acid, 2-4 parts of lauryl alcohol polyoxyethylene, a total of 6-8 parts of stabilizers including ethylene glycol and sodium alginate, wherein the ratio of parts by weight of ethylene glycol to sodium alginate is (5-7) to 1. Leaves and stems of American ginseng are by-products in the American ginseng planting industry and are not fully used all the time; saponin components in the leaves and the stems of American ginseng are pertinently extracted for preparing the hand sanitizer by using the characteristic that the stems and the leaves of the American ginseng are rich in saponin components; the prepared hand sanitizer is high in foaming performance, excellent in bacteria and stain removal effects, high in stability, free of extract precipitation after preserving the hand sanitizer for 36 months and high in uniformity.

Description

The foam type hand cleanser that a kind of plant type is degerming
Technical field
The invention belongs to household chemicals field, be specifically related to the foam type hand cleanser that a kind of plant type is degerming.
Background technology
The both hands of people will contact a lot of germy article every day, and so-called illness finds its way in by the mouth, it is simply that refers to that people eat forward (FWD) and have carefully The dirt of bacterium, thus cause sick.So the simplest when washing one's hands, need most hygienic habit, traditional when perfumed soap is washed one's hands Hand-washing article, low price, and easy to use, but if in public, people inevitably use other people to use The perfumed soap crossed, so can make a lot of people feel under the weather, because other people used article of the most uncomfortable use of most people, and wash Hand liquid avoids this problem, and most product functions on the market are single, it is impossible to meet the market demand widely.
Summary of the invention
It is an object of the invention to provide the foam type hand cleanser that a kind of plant type is degerming.
The above-mentioned purpose of the present invention is achieved by techniques below scheme:
The foam type hand cleanser that a kind of plant type is degerming, is prepared from by the raw material of following weight portion: plant extracts, 40~50 Part;Water, 55~65 parts;Glycerine, 10~20 parts;Citric acid, 3~5 parts;Ethoxylated dodecyl alcohol, 2~4 parts;Also include Stabilizer ethylene glycol and sodium alginate totally 6~8 parts, ethylene glycol and sodium alginate weight ratio are 5~7:1;
Described plant extracts is stem and leaf of Radix Panacis Quinquefolii extrac, extracts preparation method as follows:
Step S1, gathers in fresh stem and leaves of American ginseng, dries in the shade;
Step S2, dries gathering in the stem and leaves of American ginseng returning to dry in the shade, pulverized 20 mesh sieves, and obtained cauline leaf fine powder;
Step S3, extracts cauline leaf fine powder 3 times with 80% alcohol heat reflux, each 2 hours, filtrate is collected by filtration;
Step S4, filtrate reduced in volume is to without alcohol taste, with the enrichment of AB-8 type purification with macroreticular resin, first with 10% ethanol Elute 10 column volumes, then with 16 column volumes of 75% ethanol elution, collect 75% ethanol eluate;
Step S5,75% ethanol eluate reduced pressure concentration, it is spray-dried, obtains the stem and leaf of Radix Panacis Quinquefolii extrac of dry powder-shaped.
Further, described foam type hand cleanser is prepared from by the raw material of following weight portion: plant extracts, 45 parts; Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts;Also include stabilizer ethylene glycol and Sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 6:1.
Further, described foam type hand cleanser is prepared from by the raw material of following weight portion: plant extracts, 40 parts; Water, 55 parts;Glycerine, 10 parts;Citric acid, 3 parts;Ethoxylated dodecyl alcohol, 2 parts;Also include stabilizer ethylene glycol and Sodium alginate totally 6 parts, ethylene glycol and sodium alginate weight ratio are 5:1.
Further, described foam type hand cleanser is prepared from by the raw material of following weight portion: plant extracts, 50 parts; Water, 65 parts;Glycerine, 20 parts;Citric acid, 5 parts;Ethoxylated dodecyl alcohol, 4 parts;Also include stabilizer ethylene glycol and Sodium alginate totally 8 parts, ethylene glycol and sodium alginate weight ratio are 7:1.
The preparation method of above-mentioned foam type hand cleanser, comprises the steps:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Advantages of the present invention:
(1) byproduct during stem and leaves of American ginseng is American Ginseng plant husbandry, is underutilized always;The present invention utilizes its cauline leaf In be used for preparing hand cleanser rich in the feature of saponin(e, the saponin component extracted in stem and leaves of American ginseng targetedly, that makes washes one's hands Liquid foaming characteristic is strong, and degerming clean effect is good;
(2) the foam type hand cleanser good stability that the present invention provides, long term storage does not haves extract precipitation analysis for 36 months yet Occur as, uniformity is good.
(3) the natural gentleness of foam type hand cleanser that the present invention provides, can make liquid detergent, be a kind of hand cleanser and liquid detergent two-in-one Foam type washing agent.
Detailed description of the invention
Further illustrate the essentiality content of the present invention below in conjunction with embodiment, but do not limit scope with this.To the greatest extent The present invention is explained in detail by pipe with reference to preferred embodiment, it will be understood by those within the art that, can be to the present invention Technical scheme modify or equivalent, without deviating from the spirit and scope of technical solution of the present invention.
The plant extracts that the present invention uses is stem and leaf of Radix Panacis Quinquefolii extrac, extracts preparation method as follows:
Step S1, gathers in fresh stem and leaves of American ginseng, dries in the shade;
Step S2, dries gathering in the stem and leaves of American ginseng returning to dry in the shade, pulverized 20 mesh sieves, and obtained cauline leaf fine powder;
Step S3, extracts cauline leaf fine powder 3 times with 80% alcohol heat reflux, each 2 hours, filtrate is collected by filtration;
Step S4, filtrate reduced in volume is to without alcohol taste, with the enrichment of AB-8 type purification with macroreticular resin, first with 10% ethanol Elute 10 column volumes, then with 16 column volumes of 75% ethanol elution, collect 75% ethanol eluate;
Step S5,75% ethanol eluate reduced pressure concentration, it is spray-dried, obtains the stem and leaf of Radix Panacis Quinquefolii extrac of dry powder-shaped.
Embodiment 1: the preparation of foam type hand cleanser
The ratio of parts by weight of raw materials:
Plant extracts, 45 parts;Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts; Also including stabilizer ethylene glycol and sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 6:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 2: the preparation of foam type hand cleanser
The ratio of parts by weight of raw materials:
Plant extracts, 40 parts;Water, 55 parts;Glycerine, 10 parts;Citric acid, 3 parts;Ethoxylated dodecyl alcohol, 2 parts; Also including stabilizer ethylene glycol and sodium alginate totally 6 parts, ethylene glycol and sodium alginate weight ratio are 5:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 3: the preparation of foam type hand cleanser
The ratio of parts by weight of raw materials:
Plant extracts, 50 parts;Water, 65 parts;Glycerine, 20 parts;Citric acid, 5 parts;Ethoxylated dodecyl alcohol, 4 parts; Also including stabilizer ethylene glycol and sodium alginate totally 8 parts, ethylene glycol and sodium alginate weight ratio are 7:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 4: the preparation of foam type hand cleanser
The ratio of parts by weight of raw materials:
Plant extracts, 45 parts;Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts; Also including stabilizer ethylene glycol and sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 5:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 5: the preparation of foam type hand cleanser
The ratio of parts by weight of raw materials:
Plant extracts, 45 parts;Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts; Also including stabilizer ethylene glycol and sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 7:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 6: comparative example, ethylene glycol and sodium alginate weight ratio are 4:1
The ratio of parts by weight of raw materials:
Plant extracts, 45 parts;Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts; Also including stabilizer ethylene glycol and sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 4:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 7: comparative example, ethylene glycol and sodium alginate weight ratio are 8:1
The ratio of parts by weight of raw materials:
Plant extracts, 45 parts;Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts; Also including stabilizer ethylene glycol and sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 8:1.
Preparation method:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
Embodiment 8: effect example
Whether the stability of the hand cleanser of testing example 1~7 preparation, observing plant extracts therein can Precipitation.Environment Temperature 25 ± 5 DEG C, ambient humidity 50 ± 5%RH.Result such as following table.
Sample Steadiness
Embodiment 1 Stablizing in 36 months, lower floor separates out without obvious sediment, and levels homogeneity is high
Embodiment 2 Stablizing in 36 months, lower floor separates out without obvious sediment, and levels homogeneity is high
Embodiment 3 Stablizing in 36 months, lower floor separates out without obvious sediment, and levels homogeneity is high
Embodiment 4 Stablizing in 36 months, lower floor separates out without obvious sediment, and levels homogeneity is high
Embodiment 5 Stablizing in 36 months, lower floor separates out without obvious sediment, and levels homogeneity is high
Embodiment 6 Stablizing in 12 months, 18 Ge Yue lower floor colors are substantially deepened, and viscosity increases, and flocculation phenomenon occur
Embodiment 7 Stablizing in 12 months, 18 Ge Yue lower floor colors are substantially deepened, and viscosity increases, and flocculation phenomenon occur
The above results shows, the foam type hand cleanser good stability that the present invention provides, long term storage does not haves extraction in 36 months yet Thing Precipitation phenomenon, uniformity is good, and this may be relevant with stabilizer ethylene glycol in raw material and sodium alginate weight ratio, second When glycol and sodium alginate weight ratio are 5~7:1, stability is best.
Stem and leaves of American ginseng is the byproduct in American Ginseng plant husbandry, is underutilized always;The present invention utilizes in its cauline leaf rich Feature containing saponin(e, the saponin component extracted in stem and leaves of American ginseng targetedly is used for preparing hand cleanser, and the hand cleanser made rises Bubble property is strong, and degerming clean effect is good.
The effect of above-described embodiment indicates that the essentiality content of the present invention, but does not limit protection scope of the present invention with this. It will be understood by those within the art that, technical scheme can be modified or equivalent, and not take off Essence and protection domain from technical solution of the present invention.

Claims (5)

1. the foam type hand cleanser that a plant type is degerming, it is characterised in that be prepared from by the raw material of following weight portion: plant Thing extract, 40~50 parts;Water, 55~65 parts;Glycerine, 10~20 parts;Citric acid, 3~5 parts;Ethoxylated dodecyl alcohol, 2~4 parts;Also including stabilizer ethylene glycol and sodium alginate totally 6~8 parts, ethylene glycol and sodium alginate weight ratio are 5~7:1;
Described plant extracts is stem and leaf of Radix Panacis Quinquefolii extrac, extracts preparation method as follows:
Step S1, gathers in fresh stem and leaves of American ginseng, dries in the shade;
Step S2, dries gathering in the stem and leaves of American ginseng returning to dry in the shade, pulverized 20 mesh sieves, and obtained cauline leaf fine powder;
Step S3, extracts cauline leaf fine powder 3 times with 80% alcohol heat reflux, each 2 hours, filtrate is collected by filtration;
Step S4, filtrate reduced in volume is to without alcohol taste, with the enrichment of AB-8 type purification with macroreticular resin, first with 10% ethanol Elute 10 column volumes, then with 16 column volumes of 75% ethanol elution, collect 75% ethanol eluate;
Step S5,75% ethanol eluate reduced pressure concentration, it is spray-dried, obtains the stem and leaf of Radix Panacis Quinquefolii extrac of dry powder-shaped.
Foam type hand cleanser the most according to claim 1, it is characterised in that be prepared from by the raw material of following weight portion: Plant extracts, 45 parts;Water, 60 parts;Glycerine, 15 parts;Citric acid, 4 parts;Ethoxylated dodecyl alcohol, 3 parts;Also Including stabilizer ethylene glycol and sodium alginate totally 7 parts, ethylene glycol and sodium alginate weight ratio are 6:1.
Foam type hand cleanser the most according to claim 1, it is characterised in that be prepared from by the raw material of following weight portion: Plant extracts, 40 parts;Water, 55 parts;Glycerine, 10 parts;Citric acid, 3 parts;Ethoxylated dodecyl alcohol, 2 parts;Also Including stabilizer ethylene glycol and sodium alginate totally 6 parts, ethylene glycol and sodium alginate weight ratio are 5:1.
Foam type hand cleanser the most according to claim 1, it is characterised in that be prepared from by the raw material of following weight portion: Plant extracts, 50 parts;Water, 65 parts;Glycerine, 20 parts;Citric acid, 5 parts;Ethoxylated dodecyl alcohol, 4 parts;Also Including stabilizer ethylene glycol and sodium alginate totally 8 parts, ethylene glycol and sodium alginate weight ratio are 7:1.
5. the preparation method of the arbitrary described foam type hand cleanser of Claims 1 to 4, it is characterised in that comprise the steps:
Step S1, dissolves plant extracts, citric acid and sodium alginate with water, obtains blending ingredients A;
Step S2, by glycerine, ethoxylated dodecyl alcohol and ethylene glycol mixing and stirring, obtains blending ingredients B;
Step S3, is slowly added component B in component A while stirring, dispenses embedding after mixing and stirring.
CN201610303390.9A 2016-05-08 2016-05-08 A kind of foam type hand cleanser of plant type degerming Active CN105902429B (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108124915A (en) * 2018-01-15 2018-06-08 中鸿纳米纤维技术丹阳有限公司 A kind of nanometer concentrated essence liquid of potent antibacterial

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101711726A (en) * 2009-11-19 2010-05-26 同济大学 Ginseng skin-whitening liquid soap and preparation method thereof
CN102475644A (en) * 2010-11-29 2012-05-30 叶芳 Medical hand washing liquid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101711726A (en) * 2009-11-19 2010-05-26 同济大学 Ginseng skin-whitening liquid soap and preparation method thereof
CN102475644A (en) * 2010-11-29 2012-05-30 叶芳 Medical hand washing liquid

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
何小维等: "《医药用碳水化合物》", 31 January 2016 *
王笳等: "《从西洋参中提取分离纯化人参皂苷Rb1和人参皂苷Re的研究》", 《天然产物研究与开发》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108124915A (en) * 2018-01-15 2018-06-08 中鸿纳米纤维技术丹阳有限公司 A kind of nanometer concentrated essence liquid of potent antibacterial

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