CN105890955A - Automatic sputum specimen smearing instrument - Google Patents
Automatic sputum specimen smearing instrument Download PDFInfo
- Publication number
- CN105890955A CN105890955A CN201610408806.3A CN201610408806A CN105890955A CN 105890955 A CN105890955 A CN 105890955A CN 201610408806 A CN201610408806 A CN 201610408806A CN 105890955 A CN105890955 A CN 105890955A
- Authority
- CN
- China
- Prior art keywords
- double sided
- microscope slide
- axis
- slider bar
- sided slider
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 206010036790 Productive cough Diseases 0.000 title claims abstract description 48
- 210000003802 sputum Anatomy 0.000 title claims abstract description 48
- 208000024794 sputum Diseases 0.000 title claims abstract description 48
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 238000001035 drying Methods 0.000 claims abstract description 10
- 238000004043 dyeing Methods 0.000 claims description 65
- 230000005540 biological transmission Effects 0.000 claims description 19
- 230000000844 anti-bacterial effect Effects 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 7
- 239000011521 glass Substances 0.000 abstract description 8
- 238000010186 staining Methods 0.000 abstract description 7
- 238000004140 cleaning Methods 0.000 abstract description 4
- 239000012530 fluid Substances 0.000 abstract 2
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 5
- 239000000975 dye Substances 0.000 description 5
- 201000008827 tuberculosis Diseases 0.000 description 3
- 238000012864 cross contamination Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000005213 imbibition Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 208000026681 Paratuberculosis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
Abstract
The invention discloses an automatic sputum specimen smearing instrument. The automatic sputum specimen smearing instrument comprises a shell and a controller, wherein a glass slide accommodating chamber, a smearing chamber and a staining chamber are arranged inside the shell from the center to the edge in sequence, a slide outlet chamber is arranged outside the shell, a glass slide accommodating disc is arranged in the glass slide accommodating chamber, and a first lifting device is arranged between the bottom of the glass slide accommodating disc and the shell; an annular accommodating disc and a smearing device are arranged in the smearing chamber, a staining fluid bottle, a water pipe, a staining fluid collecting box and a drying device are arranged in the staining chamber, and a first pair of sliding rails, a second pair of sliding rails, a third pair of sliding rails and a fourth pair of sliding rails matched with one another are arranged in the glass slide accommodating chamber, the smearing chamber, the staining chamber and the slide outlet chamber respectively. By the adoption of the automatic sputum specimen smearing instrument, smearing, staining, drying and cleaning of a sputum specimen can be achieved automatically, operation is easy and convenient, and time is saved; opening and closing of a bottle cap and smearing are achieved through a smearing device, operation is easy and convenient, and cost is saved.
Description
Technical field
The invention mainly relates to technical field of medical instruments, specifically a kind of sputum specimen automatic smear instrument.
Background technology
The most domestic there is antibacterial automatic smear staining instruments equipment, just for general antibacterial, and cannot pin
The sputum specimen of mycobacterium tuberculosis is carried out automatic smear.At present, the sputum specimen of conventional mycobacterium tuberculosis
Smear mainly the most manually picking pus sample, caseous part sputum specimen direct smear, then dyeing microscopic examination.
The smear pollution risk of the sputum specimen of the mycobacterium tuberculosis of this routine is big, and efficiency is low.
Summary of the invention
In order to solve deficiency of the prior art, the present invention provides a kind of sputum specimen automatic smear instrument, be for
Patient's mycobacterium tuberculosis acid-fast stain checkout and diagnosis, is conveniently applied to all types tuberculosis prevention and treatment mechanism
Tuberculosis laboratory and general hospital clinical laboratory, it is possible to achieve the automatic smear of sputum specimen, dye, dry,
Clean, simple and convenient, save the time；And the opening of bottle cap, close and the carrying out of smear all uses smear
Device, simple and convenient, cost-effective.
The present invention for achieving the above object, is achieved through the following technical solutions:
Sputum specimen automatic smear instrument, including housing and controller, described enclosure interior is set to edge successively by center
Having microscope slide holding chamber, smear room and dyeing chamber, the outside of described housing is provided with slice room；
Be provided with in described microscope slide holding chamber microscope slide place disk, described microscope slide place disk bottom and
Being provided with the first lowering or hoisting gear between housing, described first lowering or hoisting gear is connected with controller, and described microscope slide is put
The top center putting disk is provided with the first motor, rotating shaft and the first hydraulic stem, one end of described first hydraulic stem
Placing disk rotational by the first rotating shaft with microscope slide to be connected, described first motor and the first rotating shaft transmission connect,
Described first motor, the first hydraulic stem are all connected with controller, and described microscope slide is placed the top of disk and is provided with
Some groups of the first double sided slider bars, described first double sided slider bar places being radially arranged of disk, and first pair along microscope slide
The circumference that slide rail places disk along microscope slide is uniformly distributed, and described first double sided slider bar slides is provided with microscope slide card
Shell, described microscope slide gets stuck and is provided with groove, places microscope slide in described groove, and the bottom of described groove sets
There are opening, the top of described housing to be provided with and place the placement mouth that disk adapts, described placement mouth with microscope slide
Place is provided with the disk cover adapted therewith；
Described smear indoor are provided with annular holding tray and smear device, described annular holding tray and microscope slide
Placement disk is coaxially disposed, and is provided with the second lowering or hoisting gear between annular holding tray and housing, described housing
Top be provided with the annular opening adapted with annular holding tray, described annular opening part is provided with therewith
The circular ring cover adapted；Described annular holding tray is provided with the second double sided slider bar adapted with the first double sided slider bar,
Described second double sided slider bar and the connection of the first double sided slider bar make microscope slide get stuck the first double sided slider bar and the second double sided slider bar it
Between move, described annular holding tray is provided with between two the second double sided slider bars through hole, pipette groove, expectorant
Specimen bottle draw-in groove, described through hole, pipette groove, sputum specimen bottle draw-in groove quantity all with second pair of cunning
The quantity of rail is identical, and the bottom of described annular holding tray is dismountable is provided with pipette dirt box, described suction
Liquid pipe dirt box connects with through hole, places pipette, described sputum specimen bottle draw-in groove in described pipette groove
Interior placement sputum specimen bottle, dismountable bottle cap that is provided with on described sputum specimen bottle, described smear device includes
The tooth bar of circular ring type, described tooth bar is arranged on circular ring cover, and described tooth bar arranges the gear being engaged with,
Described gear is slidably connected with circular ring cover by pinion stand, and described gear is rotationally connected with pinion stand, described tooth
Being additionally provided with gear motor on wheel seat, described gear motor is connected with gear drive, described pinion stand gear
Downside is provided with Y-axis support, and described Y-axis support arranges y-axis motor and vertical Y-axis leading screw, described Y
Axial filament thick stick is connected with Y-axis holder pivots, and described y-axis motor is connected with Y-axis lead screw transmission, described Y-axis silk
Being additionally provided with the Y-axis screw adapted therewith on thick stick, described Y-axis screw is provided with X-axis support, and X-axis is propped up
Frame is connected with Y-axis bracket slide, and described X-axis support is provided with the X-axis leading screw of X-axis motor and level, institute
Stating X-axis leading screw to be connected with X-axis holder pivots, described X-axis motor is connected with X-axis lead screw transmission, described X
It is additionally provided with the X-axis screw adapted therewith on axial filament thick stick, and X-axis screw is connected with X-axis bracket slide, institute
Stating X-axis screw and be provided with fixing seat, described fixing seat is provided with fixed plate, fixed plate rotating shaft and fixed plate electricity
Machine, described fixed plate is rotationally connected with fixing seat by fixed plate rotating shaft, described fixed plate rotating shaft and fixed plate
Motor-driven connects, and the bottom of described fixed plate is provided with transverse slat, transverse slat leading screw, transverse slat motor, described transverse slat
Being slidably connected with fixed plate, described transverse slat leading screw passes the center of transverse slat and is rotationally connected with transverse slat, described horizontal stroke
Board motor is connected with transverse slat lead screw transmission, and described transverse slat is fixedly installed the transverse slat silk matched with transverse slat leading screw
Mother, the lower end of described transverse slat leading screw arranges fixed block, and described fixed block arranges two connecting rods intersected,
Two connecting rods intersected all are rotationally connected with fixed block at infall, and the upper end of two connecting rods is all with horizontal
Plate is slidably connected, and the lower end of described connecting rod is provided with clamping plate；Described second lowering or hoisting gear, gear motor, Y-axis
Motor, X-axis motor, fixed plate motor, transverse slat motor are all connected with controller；
Be provided with the 3rd double sided slider bar adapted with the second double sided slider bar in described dyeing chamber, described 3rd double sided slider bar with
Second double sided slider bar connection be easy to microscope slide get stuck between the 3rd double sided slider bar and the second double sided slider bar move, described dye
Color indoor are additionally provided with dyeing liquor bottle, water pipe, dyeing liquor collection tank and drying unit, described dyeing liquor bottle
Body connects suction pumps, and described suction pumps connects has suction pipe, described suction pipe to set away from one end of dyeing liquor bottle
Have dyeing shower nozzle, described dyeing shower nozzle to be provided with nozzle switch, described nozzle switch, suction pumps all with control
Device connects, and described water pipe connects water source, and described water pipe is provided with aqueduct shower nozzle away from the one end at water source, described
Aqueduct shower nozzle is connected with controller, and described drying unit is connected with controller, described dyeing liquor collecting box position
Downside in the 3rd double sided slider bar；
Described slice indoor are provided with the 4th double sided slider bar adapted with the 3rd double sided slider bar, described 4th double sided slider bar with
3rd double sided slider bar connection be easy to microscope slide get stuck between the 3rd double sided slider bar and the 4th double sided slider bar move, described in go out
Sheet room is slidably connected with the outer rim of housing.
Being additionally provided with bactericidal unit in described housing, described bactericidal unit is connected with controller.
Described first lowering or hoisting gear includes that the second hydraulic stem, described second hydraulic stem are electrically connected with the controller.
Described microscope slide holding chamber, being equipped with dividing plate between smear room and dyeing chamber, described dividing plate is provided with confession
Microscope slide gets stuck the hole passed through.
Described second lowering or hoisting gear includes holding tray leading screw and holding tray motor, described holding tray motor and control
Device connects, and described holding tray leading screw passes annular holding tray, and described dividing plate is provided with fixed placement parcel thick stick
The mounting seat at both ends, described holding tray leading screw is rotationally connected with mounting seat, and described holding tray motor is installed on
On dividing plate, and being connected with holding tray lead screw transmission, described annular holding tray is provided with and holding tray leading screw phase
The holding tray screw adapted to, described annular holding tray is slidably connected with dividing plate.
The bottom of described dyeing liquor collection tank is provided with outlet, and in described outlet, connection has drain pipe, described in go out
Liquid pipe stretches out hull outside, and described drain pipe connects valve.
Described dyeing liquor collection tank removably connects with housing.
Contrast prior art, the present invention has the beneficial effects that:
1, the present invention be directed to patient's mycobacterium tuberculosis acid-fast stain checkout and diagnosis, be conveniently applied at different levels respectively
The tuberculosis laboratory of paratuberculosis prophylactico-therapeutic institution and general hospital clinical laboratory, can be automatically performed sputum sample
Smear, dyeing function, and can speed up the dry run of sputum sample, save the time, and pass through slice
The taking-up of sputum sample, the convenient observation that sputum sample carries out next step are easy in the setting of room.
2, by bactericidal unit, the inside of the present invention can be carried out omnibearing sterilizing, it is simple to this
Bright is the most pollution-free.
3, microscope slide can be realized very easily by the second hydraulic stem and place the lifting of disk, when microscope slide is put
When putting the top that disk rises to housing, it is simple to putting into of microscope slide, microscope slide is placed disk and is dropped to housing
Lower position time, the first double sided slider bar and the connection of the second double sided slider bar can be made, it is simple to microscope slide is sliding from first
Push on rail on the second slide rail, thus microscope slide pushed smear indoor and is easy to carry out smear in smear indoor,
Avoid during smear, microscope slide holding chamber being polluted.
4, microscope slide holding chamber, be equipped with dividing plate between smear room and dyeing chamber, the setting of dividing plate make carry glass
Environment in sheet holding chamber, smear room and dyeing chamber is mutually isolated, it is to avoid cross-contamination, and dividing plate is provided with confession
Microscope slide gets stuck the hole passed through, it is simple to what microscope slide got stuck passes through, and does not interferes with the operation of the present invention.
5, the bottom of dyeing liquor collection tank is provided with outlet, and in outlet, connection has drain pipe, drain pipe to stretch out shell
External body, drain pipe is connected and has valve, it is simple to discharged by the soiling solution in dyeing liquor collection tank by outlet
Hull outside.
6, dyeing liquor collection tank removably connects with housing, it is simple to the dismounting of dyeing liquor collection tank, thus
It is easy to the cleaning of dyeing liquor collection tank.
Accompanying drawing explanation
Accompanying drawing 1 is one of structural representation of the present invention.
Accompanying drawing 2 is the two of the structural representation of the present invention.
Accompanying drawing 3 is the structural representation of smear device.
Accompanying drawing 4 is the structural representation that microscope slide gets stuck.
Label shown in accompanying drawing: 1, housing；101, mouth is placed；102, disk cover；103, bactericidal unit；
2, controller；3, microscope slide holding chamber；301, microscope slide places disk；302, the first motor；303、
Rotating shaft；304, the first hydraulic stem；305, the first double sided slider bar；306, microscope slide gets stuck；307, groove；
308, microscope slide；309, opening；310, the second hydraulic stem；4, smear room；401, annular holding tray；
402, circular ring cover；403, the second double sided slider bar；404, through hole；405, pipette groove；406, sputum specimen
Bottle draw-in groove；407, pipette dirt box；408, pipette；409, sputum specimen bottle；410, bottle cap；
411, tooth bar；412, gear；413, pinion stand；414, gear motor；415, Y-axis support；416、
Y-axis motor；417, Y-axis leading screw；418, Y-axis screw；421, X-axis support；422, X-axis motor；423、
X-axis leading screw；424, X-axis screw；425, fixing seat；431, fixed plate；432, fixed plate rotating shaft；433、
Fixed plate motor；441, transverse slat；442, transverse slat leading screw；443, transverse slat motor；445, transverse slat screw；
446, fixed block；447, connecting rod；451, clamping plate；461, holding tray leading screw；462, holding tray screw；
463, mounting seat；464, holding tray motor；5, dyeing chamber；501, the 3rd double sided slider bar；502, dyeing liquor
Bottle；503, water pipe；504, dyeing liquor collection tank；505, drying unit；506, suction pipe；507、
Dyeing shower nozzle；508, nozzle switch；509, aqueduct shower nozzle；512, drain pipe；513, valve；6, go out
Sheet room；601, the 4th double sided slider bar；7, dividing plate.
Detailed description of the invention
In conjunction with the drawings and specific embodiments, the invention will be further described.Only should be understood that these embodiments
For the present invention being described rather than limiting the scope of the present invention.In addition, it is to be understood that say having read the present invention
After the content awarded, the present invention can be made various changes or modifications by those skilled in the art, these shapes of equal value
Formula falls within scope defined herein equally.
Sputum specimen automatic smear instrument, including housing 1 and controller 2, described housing 1 internal by center to edge
Being sequentially provided with microscope slide holding chamber 3, smear room 4 and dyeing chamber 5, the outside of described housing 1 is provided with slice room 6.
Being provided with microscope slide in described microscope slide holding chamber 3 and place disk 301, described microscope slide places disk 301
Bottom and housing 1 between be provided with the first lowering or hoisting gear, described first lowering or hoisting gear is connected with controller 2.
Control the first lowering or hoisting gear by controller 2, control microscope slide and place the lifting of disk 301.Described load glass
Sheet is placed the top center of disk 301 and is provided with the first motor 302, rotating shaft 303 and the first hydraulic stem 304, institute
The one end stating the first hydraulic stem 304 is rotationally connected by the first rotating shaft 303 and microscope slide placement disk 301,
Described first motor 302 is in transmission connection with the first rotating shaft 303, described first motor the 302, first hydraulic stem
304 are all connected with controller 2.Control the first motor 302 by controller 2 to run, then the first motor
302 rotations controlling the first hydraulic stem 304, make the first hydraulic stem 304 get stuck the microscope slide in requisition for operation
306, consequently facilitating push away microscope slide to get stuck 306.Described microscope slide is placed the top of disk 301 and is provided with some groups
First double sided slider bar 305, described first double sided slider bar 305 is radially arranged along microscope slide placement disk 301, and the
The circumference that one double sided slider bar 305 places disk 301 along microscope slide is uniformly distributed, on described first double sided slider bar 305
Slip is provided with microscope slide and gets stuck 306.Described microscope slide gets stuck and 306 is provided with groove 307, described groove 307
Interior placement microscope slide 308, the bottom of described groove 307 is provided with opening 309, it is simple to follow-up microscope slide 308
Dry after dyeing.The top of described housing 1 is provided with places, with microscope slide, the placement that disk 301 adapts
Mouth 101, is provided with the disk cover 102 adapted therewith at described placement mouth 101.
Annular holding tray 401 and smear device, described annular holding tray 401 it is provided with in described smear room 4
Place disk 301 with microscope slide to be coaxially disposed, and be provided with second between annular holding tray 401 and housing 1
Lowering or hoisting gear, controls the lifting of annular holding tray 401 by the second lowering or hoisting gear, consequently facilitating annular
Pipette 408, the placement of sputum specimen bottle 409 on holding tray 401.The top of described housing 1 is provided with and circle
The annular opening that annular holding tray 401 adapts, described annular opening part is provided with the circle adapted therewith
Ring cowling 402, matches with disk cover 102, can individually open disk cover 102 or circular ring cover 402, letter
Folk prescription is just.Described annular holding tray 401 is provided with the second double sided slider bar adapted with the first double sided slider bar 305
403, described second double sided slider bar 403 connects with the first double sided slider bar 305 and makes microscope slide get stuck 306 first pair of cunning
Move between rail 305 and the second double sided slider bar 403.Two the second double sided slider bars on described annular holding tray 401
Through hole 404, pipette groove 405, sputum specimen bottle draw-in groove 406 it is provided with, it is preferred that along being coated with between 403
The rotation direction of sheet devices sets gradually through hole 404, pipette groove 405, sputum specimen bottle draw-in groove 406,
Thus realize smear device and grip pipette 408 from pipette groove 405, smear device turns an angle,
Then to microscope slide 308 smear, after smear completes, smear device is rotated further by certain angle, crosses microscope slide 308,
By making the pipette 408 being finished put into through hole 404, operate regular, and will not be to microscope slide when smear
308 pollute.Described through hole 404, pipette groove 405, sputum specimen bottle draw-in groove 406 quantity equal
Identical with the quantity of the second double sided slider bar 403.The bottom of described annular holding tray 401 is dismountable is provided with suction
Liquid pipe dirt box 407, described pipette dirt box 407 connects with through hole 404, makes the pipette 408 being finished
Pipette dirt box 407 is called in, it is simple to make the collection of the pipette 408 being finished from through hole 404.Described imbibition
Place pipette 408 in pipe groove 405, in described sputum specimen bottle draw-in groove 406, place sputum specimen bottle 409,
Dismountable bottle cap 410 that is provided with on described sputum specimen bottle 409, bottle cap 410 and sputum specimen bottle 409 screw thread
Connect, the good airproof performance that bottle cap 410 covers.Described smear device includes the tooth bar 411 of circular ring type, described tooth
Bar 411 is arranged on circular ring cover 402, and described tooth bar 411 arranges the gear 412 being engaged with, described tooth
Wheel 412 is slidably connected with circular ring cover 402 by pinion stand 413, described gear 412 and pinion stand 413 turns
It is dynamically connected, described pinion stand 413 is additionally provided with gear motor 414, described gear motor 414 and gear 412
It is in transmission connection.Smear device is made to rotate around circular ring cover 402 by tooth bar 411, it is simple to the load to different azimuth
Slide 308 carries out smear.The downside of described pinion stand 413 gear 412 is provided with Y-axis support 415, described
Y-axis motor 416 and vertical Y-axis leading screw 417 be set on Y-axis support 415, described Y-axis leading screw 417 with
Y-axis support 415 is rotationally connected, and described y-axis motor 416 is in transmission connection with Y-axis leading screw 417, described Y-axis
Being additionally provided with the Y-axis screw 418 adapted therewith on leading screw 417, described Y-axis screw 418 is provided with X-axis and props up
Frame 421, and X-axis support 421 is slidably connected with Y-axis support 415.X-axis is controlled by y-axis motor 416
Support 421 vertical direction moves, thus controls the smear device movement at vertical direction.Described X-axis support
The 421 X-axis leading screws 423 being provided with X-axis motor 422 and level, described X-axis leading screw 423 and X-axis support
421 are rotationally connected, and described X-axis motor 422 is in transmission connection with X-axis leading screw 423, described X-axis leading screw 423
On be additionally provided with the X-axis screw 424 adapted therewith, and X-axis screw 424 is slidably connected with X-axis support 421,
X-axis screw 424 can be made to move in the direction of level.Described X-axis screw 424 is provided with fixing seat 425,
Described fixing seat 425 is provided with fixed plate 431, fixed plate rotating shaft 432 and fixed plate motor 433, described solid
Determine plate 431 to be rotationally connected with fixing seat 425 by fixed plate rotating shaft 432, described fixed plate rotating shaft 432 and
Fixed plate motor 433 is in transmission connection, the bottom of described fixed plate 431 be provided with transverse slat 441, transverse slat leading screw 442,
Transverse slat motor 443, described transverse slat 441 is slidably connected with fixed plate 431, and described transverse slat leading screw 442 is through horizontal stroke
The center of plate 441 and being rotationally connected with transverse slat 441, described transverse slat motor 443 and transverse slat leading screw 442 transmission
Connect, described transverse slat 441 is fixedly installed the transverse slat screw 445 matched with transverse slat leading screw 442, described horizontal stroke
The lower end of plate leading screw 442 arranges fixed block 446, and described fixed block 446 arranges two connecting rods intersected
447, two connecting rods 447 intersected all are rotationally connected with fixed block 446 at infall, and two connecting rods
The upper end of 447 is all slidably connected with transverse slat 441, and the lower end of described connecting rod 447 is provided with clamping plate 451, clamping plate
451 control opening of bottle cap 410 for gripping bottle cap 410, or gripping pipette 408, control to inhale
Sputum drawn by liquid pipe 408, then to microscope slide 308 smear.Described second lowering or hoisting gear, gear motor 414,
Y-axis motor 416, X-axis motor 422, fixed plate motor 433, transverse slat motor 443 are all connected with controller 2.
The 3rd double sided slider bar 501 adapted with the second double sided slider bar 403 it is provided with in described dyeing chamber 5, the described 3rd
Double sided slider bar 501 connects with the second double sided slider bar 403 to be easy to microscope slide and gets stuck 306 at the 3rd double sided slider bar 501 and
Move between two double sided slider bars 403.Dyeing liquor bottle 502, water pipe 503, dye it is additionally provided with in described dyeing chamber 5
Color liquid collection tank 504 and drying unit 505, described dyeing liquor bottle 502 connects suction pumps, described suction
Liquid pump connects has suction pipe 506, described suction pipe 506 to be provided with dyeing shower nozzle away from one end of dyeing liquor bottle 502
507, described dyeing shower nozzle 507 is provided with nozzle switch 508, described nozzle switch 508, suction pumps all with
Controller 2 connects.Number and the kind of dyeing liquor bottle 502 can be arranged as required to.One dyeing liquor
Bottle 502 can connect a suction pipe 506, and right later suction pipe 506 connects a dyeing shower nozzle 507,
Then by the movement of existing manipulator control dyeing shower nozzle 507, microscope slide 308 is dyeed；Also
Dyeing liquor bottle 502 connection can have multiple suction pipe 506, on right later suction pipe 506, connection has multiple
Dyeing shower nozzle 507, each dyeing shower nozzle 507 correspondence a nozzle switch 508, the most each dye are set
The top being arranged on microscope slide 308 of color shower nozzle 507 correspondence, controls each shower nozzle by controller 2 and opens
Opening and closing of pass 508, dyes to corresponding microscope slide 308.After glass slide dyeing completes,
Control drying unit 505 by controller 2 microscope slide 308 is dried, simple and convenient, save the time.
Described water pipe 503 connects water source, and water source can be that the external water source connected can also set in dyeing chamber 5
Having the cylinder being filled with water, described water pipe 503 is provided with aqueduct shower nozzle 509, described aqueduct shower nozzle away from the one end at water source
509 are connected with controller 2, after microscope slide 308 has dyeed and dried, are controlled by controller 2
Opening of aqueduct shower nozzle 509, is rinsed microscope slide 308, described drying unit 505 and controller 2
Connect.Described dyeing liquor collection tank 504 is positioned at the downside of the 3rd double sided slider bar 501, it is simple to dyeing liquor and punching
Wash the collection of the sewage of dyeing liquor and focus on.
The 4th double sided slider bar 601 adapted with the 3rd double sided slider bar 501 it is provided with in described slice room 6, the described 4th
Double sided slider bar 601 connects with the 3rd double sided slider bar 501 to be easy to microscope slide and gets stuck 306 at the 3rd double sided slider bar 501 and
Moving between four double sided slider bars 601, described slice room 7 is slidably connected with the outer rim of housing 1.When smear completes
After, controlling the first hydraulic stem 304 by controller 2 and extend, being got stuck by microscope slide 306 pushes the 4th pair of cunning
On rail 601, consequently facilitating the continuation of microscope slide 308 that smear completes is observed.Can also be in slice room 6
It is provided with microscope camera, in slice room 6, directly observes microscope slide 308.
In order to keep the cleaning of the present invention and make to be in inside the present invention sterile device, in described housing 1 also
Being provided with bactericidal unit 103, described bactericidal unit 103 is connected with controller 2, and bactericidal unit 103 can be red
Outside line bactericidal unit.
Described first lowering or hoisting gear includes the second hydraulic stem 310, described second hydraulic stem 310 and controller 2 electricity
Connect, when microscope slide 308 placed by needs, controlled the elongation of the second hydraulic stem 310 by controller 2,
So that microscope slide is placed disk 301 and is risen, it is simple to the microscope slide of putting into of microscope slide 308 gets stuck 306；
After microscope slide 308 has been placed, controlled the shortening of the second hydraulic stem 310 by controller 2, so that
Microscope slide place disk 301 drop to concordant with annular holding tray 401, it is simple to microscope slide get stuck 306 by
First double sided slider bar 305 pushes the second double sided slider bar 403 of annular holding tray 401.
Further, between described microscope slide holding chamber 3, smear room 4 and dyeing chamber 5, it is equipped with dividing plate 7,
Make the environment in microscope slide holding chamber 3, smear room 4 and dyeing chamber 5 mutually isolated, it is to avoid cross-contamination,
Described dividing plate 7 is provided with and gets stuck 306 holes passed through for microscope slide, it is simple to microscope slide gets stuck 306 pass through,
Do not interfere with the operation of the present invention.
Described second lowering or hoisting gear includes holding tray leading screw 461 and holding tray motor 464, described holding tray motor
464 are connected with controller 2, and described holding tray leading screw 461 is through annular holding tray 401, described dividing plate 7
It is provided with the mounting seat 463 at fixed placement parcel thick stick 461 both ends, described holding tray leading screw 461 and mounting seat
463 are rotationally connected, and described holding tray motor 464 is installed on dividing plate 7, and holding tray motor 464 with place
Parcel thick stick 461 is in transmission connection, and described annular holding tray 401 is provided with and adapts with holding tray leading screw 461
Holding tray screw 462, described annular holding tray 401 is slidably connected with dividing plate 7.When imbibition placed by needs
When pipe 408 and sputum specimen bottle 409, control holding tray motor 464 by controller 2 and run, make second
Lowering or hoisting gear controls the rising of annular holding tray 401, when having placed pipette 408 and sputum specimen bottle 409
After, control holding tray motor 464 by controller 2 and run, make the second lowering or hoisting gear control annular and place
Dropping to of dish 401 is concordant with microscope slide placement disk 301, makes first double sided slider bar the 305, second double sided slider bar
403, the 3rd double sided slider bar 501 is concordant, it is simple to microscope slide gets stuck and 306 pushed annular by the first double sided slider bar 305
Second double sided slider bar 403 of holding tray 401, then pushed the 3rd double sided slider bar 501 by the second double sided slider bar 403.
Flow out for the ease of the soiling solution within dyeing liquor collection tank 504, described dyeing liquor collection tank 504
Bottom be provided with outlet, in described outlet, connection has drain pipe 512, described drain pipe 512 to stretch out outside housing 1
Portion, described drain pipe 512 connects and has valve 513, by opening or closure valve 513, controls dyeing liquor
The outflow of the soiling solution in collection tank 504.
Further, described dyeing liquor collection tank 504 removably connects with housing 1, it is simple to dyeing liquor is received
The collection replacing of casing 504, cleaning, sterilizing.
Claims (7)
1. sputum specimen automatic smear instrument, including housing (1) and controller (2), is characterized in that: described housing
(1) inside is sequentially provided with microscope slide holding chamber (3), smear room (4) and dyeing chamber (5) by center to edge,
The outside of described housing (1) is provided with slice room (6)；
Being provided with microscope slide in described microscope slide holding chamber (3) and place disk (301), described microscope slide places circle
It is provided with the first lowering or hoisting gear, described first lowering or hoisting gear and control between bottom and the housing (1) of dish (301)
Device processed (2) connect, described microscope slide place disk (301) top center be provided with the first motor (302),
Rotating shaft (303) and the first hydraulic stem (304), one end of described first hydraulic stem (304) passes through first turn
Axle (303) and microscope slide are placed disk (301) and are rotationally connected, described first motor (302) and first turn
Axle (303) is in transmission connection, described first motor (302), the first hydraulic stem (304) all with controller (2)
Connecting, described microscope slide is placed the top of disk (301) and is provided with some groups of the first double sided slider bars (305), described
First double sided slider bar (305) places being radially arranged of disk (301), and the first double sided slider bar (305) along microscope slide
The circumference placing disk (301) along microscope slide is uniformly distributed, and the upper slip of described first double sided slider bar (305) sets
Have microscope slide to get stuck (306), described microscope slide get stuck (306) be provided with groove (307), described groove (307)
Interior placement microscope slide (308), the bottom of described groove (307) is provided with opening (309), described housing (1)
Top be provided with and place disk (301) the placement mouth (101) that adapts, described placement mouth (101) with microscope slide
Place is provided with the disk cover (102) adapted therewith；
Annular holding tray (401) and smear device, described annular holding tray it is provided with in described smear room (4)
(401) place disk (301) with microscope slide to be coaxially disposed, and annular holding tray (401) and housing (1)
Between be provided with the second lowering or hoisting gear, the top of described housing (1) is provided with and annular holding tray (401) phase
The annular opening adapted to, described annular opening part is provided with the circular ring cover (402) adapted therewith；Described
Annular holding tray (401) is provided with the second double sided slider bar (403) adapted with the first double sided slider bar (305),
Described second double sided slider bar (403) connects with the first double sided slider bar (305) and makes microscope slide get stuck (306) first
Move between double sided slider bar (305) and the second double sided slider bar (403), described annular holding tray (401) upper two
Through hole (404), pipette groove (405), sputum specimen bottle card it is provided with between individual second double sided slider bar (403)
Groove (406), described through hole (404), pipette groove (405), the number of sputum specimen bottle draw-in groove (406)
Measuring all identical with the quantity of the second double sided slider bar (403), the bottom of described annular holding tray (401) is removable
That unloads is provided with pipette dirt box (407), and described pipette dirt box (407) connects with through hole (404),
Place in pipette (408), described sputum specimen bottle draw-in groove (406) in described pipette groove (405)
Placing sputum specimen bottle (409), described sputum specimen bottle (409) is the most dismountable is provided with bottle cap (410),
Described smear device includes the tooth bar (411) of circular ring type, and described tooth bar (411) is arranged at circular ring cover (402)
On, described tooth bar (411) above arranges the gear (412) being engaged with, and described gear (412) passes through tooth
Wheel seat (413) is slidably connected with circular ring cover (402), and described gear (412) turns with pinion stand (413)
It is dynamically connected, described pinion stand (413) is additionally provided with gear motor (414), described gear motor (414)
Being in transmission connection with gear (412), the downside of described pinion stand (413) gear (412) is provided with Y-axis and props up
Frame (415), described Y-axis support (415) arranges y-axis motor (416) and vertical Y-axis leading screw (417),
Described Y-axis leading screw (417) is rotationally connected with Y-axis support (415), described y-axis motor (416) and Y
Axial filament thick stick (417) is in transmission connection, and described Y-axis leading screw (417) is additionally provided with the Y-axis silk adapted therewith
Female (418), described Y-axis screw (418) is provided with X-axis support (421), and X-axis support (421)
Be slidably connected with Y-axis support (415), described X-axis support (421) be provided with X-axis motor (422) and
The X-axis leading screw (423) of level, described X-axis leading screw (423) is rotationally connected with X-axis support (421),
Described X-axis motor (422) is in transmission connection with X-axis leading screw (423), and described X-axis leading screw (423) is upper also
It is provided with the X-axis screw (424) adapted therewith, and X-axis screw (424) is sliding with X-axis support (421)
Being dynamically connected, described X-axis screw (424) is provided with fixing seat (425), and described fixing seat (425) sets
There are fixed plate (431), fixed plate rotating shaft (432) and fixed plate motor (433), described fixed plate (431)
Be rotationally connected with fixing seat (425) by fixed plate rotating shaft (432), described fixed plate rotating shaft (432) with
Fixed plate motor (433) is in transmission connection, and the bottom of described fixed plate (431) is provided with transverse slat (441), horizontal stroke
Plate leading screw (442), transverse slat motor (443), described transverse slat (441) is slidably connected with fixed plate (431),
Described transverse slat leading screw (442) passes the center of transverse slat (441) and is rotationally connected with transverse slat (441), described
Transverse slat motor (443) is in transmission connection with transverse slat leading screw (442), described transverse slat (441) is fixedly installed with
The transverse slat screw (445) that transverse slat leading screw (442) matches, the lower end of described transverse slat leading screw (442) is arranged
Fixed block (446), described fixed block (446) arranges two connecting rods (447) intersected, two intersections
Connecting rod (447) be all rotationally connected with fixed block (446) at infall, and two connecting rods (447)
Upper end be all slidably connected with transverse slat (441), the lower end of described connecting rod (447) is provided with clamping plate (451)；
Described second lowering or hoisting gear, gear motor (414), y-axis motor (416), X-axis motor (422), fixing
Board motor (433), transverse slat motor (443) are all connected with controller (2)；
The 3rd double sided slider bar (501) adapted with the second double sided slider bar (403) it is provided with in described dyeing chamber (5),
Described 3rd double sided slider bar (501) connects with the second double sided slider bar (403) to be easy to microscope slide and gets stuck (306)
Moving between three double sided slider bars (501) and the second double sided slider bar (403), described dyeing chamber is additionally provided with dye in (5)
Color liquid bottle (502), water pipe (503), dyeing liquor collection tank (504) and drying unit (505), institute
Stating dyeing liquor bottle (502) connection and have suction pumps, described suction pumps connects suction pipe (506), described suction pipe
(506) one end away from dyeing liquor bottle (502) is provided with dyeing shower nozzle (507), described dyeing shower nozzle (507)
Being provided with nozzle switch (508), described nozzle switch (508), suction pumps are all connected with controller (2),
Described water pipe (503) connects has water source, described water pipe (503) to be provided with aqueduct shower nozzle away from the one end at water source
(509), described aqueduct shower nozzle (509) is connected with controller (2), described drying unit (505) and control
Device processed (2) connects, and described dyeing liquor collection tank (504) is positioned at the downside of the 3rd double sided slider bar (501)；
It is provided with, in described slice room (6), the 4th double sided slider bar (601) adapted with the 3rd double sided slider bar (501),
Described 4th double sided slider bar (601) connects with the 3rd double sided slider bar (501) to be easy to microscope slide and gets stuck (306)
Move between three double sided slider bars (501) and the 4th double sided slider bar (601), described slice room (7) and housing (1)
Outer rim be slidably connected.
Sputum specimen automatic smear instrument the most according to claim 1, is characterized in that: described housing (1)
Inside being additionally provided with bactericidal unit (103), described bactericidal unit (103) is connected with controller (2).
Sputum specimen automatic smear instrument the most according to claim 1, is characterized in that: described first lifting dress
Putting and include the second hydraulic stem (310), described second hydraulic stem (310) electrically connects with controller (2).
Sputum specimen automatic smear instrument the most according to claim 1, is characterized in that: described microscope slide is placed
Being equipped with dividing plate (7) between room (3), smear room (4) and dyeing chamber (5), described dividing plate sets on (7)
Have and get stuck the hole that (306) pass through for microscope slide.
Sputum specimen automatic smear instrument the most according to claim 4, is characterized in that: described second lifting dress
Put and include that holding tray leading screw (461) and holding tray motor (464), described holding tray leading screw (461) pass
Annular holding tray (401), described dividing plate (7) is provided with fixed placement parcel thick stick (461) both ends
Mounting seat (463), described holding tray leading screw (461) is rotationally connected with mounting seat (463), described placement
Coil motor (464) is installed on dividing plate (7), and is in transmission connection with holding tray leading screw (461), described circle
Annular holding tray (401) is provided with the holding tray screw (462) adapted with holding tray leading screw (461),
Described annular holding tray (401) is slidably connected with dividing plate (7).
Sputum specimen automatic smear instrument the most according to claim 1, is characterized in that: described dyeing liquor is collected
The bottom of casing (504) is provided with outlet, and in described outlet, connection has drain pipe (512), described drain pipe (512)
Stretching out housing (1) outside, the upper connection of described drain pipe (512) has valve (513).
Sputum specimen automatic smear instrument the most according to claim 1, is characterized in that: described dyeing liquor is collected
Casing (504) removably connects with housing (1).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610408806.3A CN105890955B (en) | 2016-06-12 | 2016-06-12 | Sputum specimen automatic smear instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610408806.3A CN105890955B (en) | 2016-06-12 | 2016-06-12 | Sputum specimen automatic smear instrument |
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| CN105890955B CN105890955B (en) | 2018-06-19 |
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| CN201610408806.3A Expired - Fee Related CN105890955B (en) | 2016-06-12 | 2016-06-12 | Sputum specimen automatic smear instrument |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106771288A (en) * | 2017-01-20 | 2017-05-31 | 安徽理工大学 | A kind of Mycobacterium tuberculosis automatic checkout equipment |
| CN106769291A (en) * | 2016-12-06 | 2017-05-31 | 山东鼎创数控设备有限公司 | A kind of automatic stamping formula Medical glass slide application device |
| CN106840815A (en) * | 2017-01-20 | 2017-06-13 | 杜鹏 | One kind automation medical test blood heap piece overflow dyeing machine |
| CN108535079A (en) * | 2018-05-31 | 2018-09-14 | 广州江元医疗科技有限公司 | A kind of multi-functional slide fixation turntable |
| CN114112576A (en) * | 2021-11-22 | 2022-03-01 | 驻马店市中心医院 | Mycobacterium tuberculosis drug resistance detection system based on acid-fast staining of sputum smear |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03209163A (en) * | 1990-01-11 | 1991-09-12 | Chiyoda Seisakusho:Kk | Method and device for extending chromosome on slide glass |
| WO2005010186A1 (en) * | 2003-07-29 | 2005-02-03 | All India Institute Of Medical Sciences (A.I.I.M.S.) | A method for diagnosis of tuberculosis by smear microscopy, culture and polymerase chain reaction using processed clinical samples and kit thereof |
| CN1789957A (en) * | 2005-12-10 | 2006-06-21 | 王海波 | Automatic sputum smear staining instrument for medical use and staining method thereof |
| CN201681009U (en) * | 2010-02-03 | 2010-12-22 | 陈子芳 | Tubercle bacillus staining device |
| CN102243243A (en) * | 2010-05-13 | 2011-11-16 | 南京神州英诺华医疗科技有限公司 | Novel instrument for automatically processing phlegm sample |
| CN202204718U (en) * | 2011-09-22 | 2012-04-25 | 汕头大学医学院第一附属医院 | Slide specimen dyeing machine |
| CN103558071A (en) * | 2013-11-08 | 2014-02-05 | 上海微银生物技术有限公司 | Full-automatic phlegm specimen smearing instrument, system and method |
| CN203929476U (en) * | 2014-04-30 | 2014-11-05 | 王海波 | Automatic smear overflow dyeing machine |
| CN104777026A (en) * | 2014-01-14 | 2015-07-15 | 苏州微利特生物科技有限公司 | Liquid-dropping type automatic biological staining instrument |
-
2016
- 2016-06-12 CN CN201610408806.3A patent/CN105890955B/en not_active Expired - Fee Related
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03209163A (en) * | 1990-01-11 | 1991-09-12 | Chiyoda Seisakusho:Kk | Method and device for extending chromosome on slide glass |
| WO2005010186A1 (en) * | 2003-07-29 | 2005-02-03 | All India Institute Of Medical Sciences (A.I.I.M.S.) | A method for diagnosis of tuberculosis by smear microscopy, culture and polymerase chain reaction using processed clinical samples and kit thereof |
| CN1789957A (en) * | 2005-12-10 | 2006-06-21 | 王海波 | Automatic sputum smear staining instrument for medical use and staining method thereof |
| CN201681009U (en) * | 2010-02-03 | 2010-12-22 | 陈子芳 | Tubercle bacillus staining device |
| CN102243243A (en) * | 2010-05-13 | 2011-11-16 | 南京神州英诺华医疗科技有限公司 | Novel instrument for automatically processing phlegm sample |
| CN202204718U (en) * | 2011-09-22 | 2012-04-25 | 汕头大学医学院第一附属医院 | Slide specimen dyeing machine |
| CN103558071A (en) * | 2013-11-08 | 2014-02-05 | 上海微银生物技术有限公司 | Full-automatic phlegm specimen smearing instrument, system and method |
| CN104777026A (en) * | 2014-01-14 | 2015-07-15 | 苏州微利特生物科技有限公司 | Liquid-dropping type automatic biological staining instrument |
| CN203929476U (en) * | 2014-04-30 | 2014-11-05 | 王海波 | Automatic smear overflow dyeing machine |
Non-Patent Citations (2)
| Title |
|---|
| 訾昌达: "痰涂片和结核杆菌培养在肺结核筛查中的应用分析", 《医学信息》 * |
| 陈险峰 等: "痰标本涂片革兰染色镜检的临床意义", 《检验医学》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106769291A (en) * | 2016-12-06 | 2017-05-31 | 山东鼎创数控设备有限公司 | A kind of automatic stamping formula Medical glass slide application device |
| CN106771288A (en) * | 2017-01-20 | 2017-05-31 | 安徽理工大学 | A kind of Mycobacterium tuberculosis automatic checkout equipment |
| CN106840815A (en) * | 2017-01-20 | 2017-06-13 | 杜鹏 | One kind automation medical test blood heap piece overflow dyeing machine |
| CN106771288B (en) * | 2017-01-20 | 2018-06-01 | 安徽理工大学 | A kind of Mycobacterium tuberculosis automatic checkout equipment |
| CN106840815B (en) * | 2017-01-20 | 2019-04-26 | 杜鹏 | A kind of automation medical test blood heap piece overflow dyeing machine |
| CN108535079A (en) * | 2018-05-31 | 2018-09-14 | 广州江元医疗科技有限公司 | A kind of multi-functional slide fixation turntable |
| CN114112576A (en) * | 2021-11-22 | 2022-03-01 | 驻马店市中心医院 | Mycobacterium tuberculosis drug resistance detection system based on acid-fast staining of sputum smear |
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