CN105878282A - Health care product with compatibility of bezoar and nitric oxide, and preparation method thereof - Google Patents
Health care product with compatibility of bezoar and nitric oxide, and preparation method thereof Download PDFInfo
- Publication number
- CN105878282A CN105878282A CN201610315093.6A CN201610315093A CN105878282A CN 105878282 A CN105878282 A CN 105878282A CN 201610315093 A CN201610315093 A CN 201610315093A CN 105878282 A CN105878282 A CN 105878282A
- Authority
- CN
- China
- Prior art keywords
- milligram
- bezoar
- cow
- nitric oxide
- health products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title claims abstract description 76
- 206010004542 Bezoar Diseases 0.000 title claims abstract description 40
- 230000036541 health Effects 0.000 title claims abstract description 33
- 238000002360 preparation method Methods 0.000 title claims abstract description 25
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 20
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims abstract description 11
- 229930064664 L-arginine Natural products 0.000 claims abstract description 11
- 235000014852 L-arginine Nutrition 0.000 claims abstract description 11
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- 239000002775 capsule Substances 0.000 claims description 14
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 12
- 239000002994 raw material Substances 0.000 claims description 11
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- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 claims description 6
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K35/413—Gall bladder; Bile
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Abstract
The invention discloses a health care product with compatibility of bezoar and nitric oxide, and a preparation method thereof in the technical field of health care products. Each 10 g of the health care product is prepared from the following ingredients in parts by weight: 100-1500mg of bezoar, 1500-3000mg of L-arginine, 1500-3000mg of L-citrulline and 500-2000mg of taurine. The function of the invention is to provide the health care product capable of enhancing the elasticity of vascular smooth muscle, removing a risk factor which causes atherosclerosis, preventing vascular endothelial cells from being damaged, improving the blood circulation, increasing the blood flow of important organs including the brain, the heart, the pancreas, the kidney, the prostate, the genitals and the like, and guaranteeing that the nutrition supply and the waste removal of each important organ of the organism so as to enhance the physiological function of each important organ of the organism.
Description
Technical field
The present invention relates to health product technology field, particularly to a kind of health products with cow-bezoar and nitric oxide compatibility and preparation method thereof.
Background technology
China has been enter into aging society at present, thereby results in the multiple of various geriatric disease.The incidences of disease such as headstroke, coronary heart disease, hypertension, diabetes, pancreatitis, tumour increase year by year, along with the raising of people's living standard, prevent and treat various geriatric disease, delay senility and become focus of concern.The second half in last century, it has been found that nitric oxide is that human body is widely distributed, have protection the heart, brain, pancreas, kidney, blood vessel, etc. vitals.Reduce the function that the heart, brain, pancreas, kidney, illness and other geriatric diseases occur.Causing many concerns with economic mind personage, countries in the world are developed the most one after another and have been occurred as soon as nine nitric oxide production commodity of what is called before and after indicating nitric oxide production commodity, the only U.S..Regrettably, the most short-lived, the most just make no public appearances.Have is invalid, and some side effects are too big, and some valencys are high, user is difficult to accept, and trace it to its cause, and is all that formula is out of joint.
Summary of the invention
It is an object of the invention to provide a kind of with cow-bezoar with the health products of nitric oxide compatibility, the two can protect vascular endothelial cell synergistically to Green Tea Extract, efficiently from the infringement of free radical.Strengthen blood vessel elasticity, protect the blood supply of the vitals such as brain, the heart, liver, kidney, pancreas, prostate efficiently.Ensure the normal long journey of vitals high-effectly.Particularly dispel the peroxidating low-density lipoprotein piled up in person in middle and old age male human sex organ, i.e. bad cholesterol, it is ensured that in cavernous body, tiny blood vessels is unobstructed, make blood can pour cavernous body, form telotism.As a same reason, owing to female sexual organ CBF increases, various excitability media are prone to produce, it is easier to diffuse to whole body, promote women to be more easy to obtain pleasant sensation.For middle-aged women, owing to the CBF of reproductive organs increases, the various bodies of gland relevant with menstrual period postpone atrophy, therefore can postpone the arriving in middle-aged women climacteric.
These health products compatibility is reasonable, has no adverse reaction.
Cow-bezoar in formula has the function removing free radical, reduces the generation of low-density lipoprotein, reduces bad cholesterol in endovascular accumulation, it is ensured that the normal physiological function of each vitals,
L-arginine in formula, Cit, and be positioned at the Nitric oxide syntheses of each organ of human body, after catalytic action, and generating functionality molecule " nitric oxide ".Effectively playing various biological effect, the two organically coordinates, and has played the synergy of mystery.
It is a further object of the present invention to provide above-mentioned a kind of health products preparation method with cow-bezoar and nitric oxide compatibility.
To achieve these goals; the present invention provides a kind of with cow-bezoar with the health products of nitric oxide compatibility, and the weight proportion of every 10 grams of described health products is: cow-bezoar 100-1500 milligram, L-arginine 1500-3000 milligram, Cit 1500-3000 milligram, taurine 500-2000 milligram.
Further improvement is that of such scheme: the weight proportion of every 10 grams of described health products is: cow-bezoar 100-1500 milligram, L-arginine 1500-3000 milligram, Cit 1500-3000 milligram, taurine 500-2000 milligram, Co-Q10 150-250 milligram, VC 350-500 milligram, VE
200-400 milligram, OPC 40-90 milligram, grape seed extract 100-150 milligram, Ganodenna Lucidum P.E 200-300 milligram, hawthorn flavone extract 100-150 milligram, ginkgo biloba extract 100-150 milligram, Astragalus Root P.E 10-100 milligram, bata-carotene 20-30 milligram, lipoic acid 500-600 milligram, folic acid 600-800 microgram, selenium 80-100 microgram.
The preparation method of the above-mentioned health products that the present invention provides, comprises the steps:
Select materials, weigh the raw material of suitable requirement according to certain mass standard；
Mixing, mixes above-mentioned weighed raw material under 0～20 degree Celsius；
Pulverize, the above-mentioned raw material mixed was pulverized 80 mesh sieves by pulverizer；
Preparation, is respectively prepared capsule, pill, tablet by the powder stock after above-mentioned sieving according to conventional formulation method, makes finished product；
Sterilizing, the CO of finished product 6KGY60Irradiation sterilization；
Production environment cleanliness factor 100,000 grades.
The preparation method of above-mentioned capsule is: is loaded by powder stock in hungry area softgel shell, i.e. makes capsule.
The preparation method of above-mentioned pill is: by powder stock refined honey and even, rubbing, through pellet processing machine pill pill.
The preparation method of above-mentioned tablet is: powder stock is added adhesive, pelletizes, dries, whole grain, tabletting machine, i.e. piece agent.
The present invention a kind of with cow-bezoar with the health products of nitric oxide compatibility, has the beneficial effects that:
Cow-bezoar, in first five century in Christian era, well-known doctor Bian Que finds that cow-bezoar, Tang Tang materia medica claim: " cow-bezoar takes increasing year of can making light of one's life by commiting suicide for a long time, makes us not forgetting ".Modern medicine research proves, cow-bezoar has extremely strong scavenging action to superoxide radical and hydroxy radical.Cow-bezoar can improve internal SOD activity, reduces the generation of low-density lipoprotein, on the one hand can directly protect the vitals such as the heart, brain, kidney, pancreas, prostate to exempt from the infringement of free radical；On the other hand minimizing low-density lipoprotein is in endovascular accumulation, thus ensures the unobstructed blood of the vitals such as the heart, brain, kidney, pancreas, prostate, also ensure that the normal physiological function of the vitals such as the heart, brain, kidney, pancreas, prostate.Study of pharmacy in the recent period finds, it is bilirubin sodium that cow-bezoar plays the main component of above-mentioned effect, and the past thinks that bilirubin sodium is the metabolite needing excretion always, has no physiological function；Modern medicine research shows, bilirubin sodium is naturally occurring one efficient physiological antioxidant in human body, is the important component part of human body antioxidant system, accounts for the 30% of human body oxidation resistance.The rarity of motherland's medicine " cow-bezoar be ", qualified.
Nitric oxide, is the product under nitric oxide enzyme catalysis of the arginine in body, produces citrulling simultaneously, and citrulling combines with internal ammonia again, regeneration arginine；So iterative cycles, constantly produces nitric oxide, and this process is exactly famous citrulling circulation.Here, it should be noted that, the generation of body intracellular nitric oxide, substantial connection is there is with arginine, citrulling, because arginine and citrulling also participate in muscle and collagen and the biosynthesis of various enzyme, it is accordingly required in particular to it is noted that for person in middle and old age, arginine and citrulling can gradually decrease, and even exhaust.Thus affect citrulling circulation, also affect nitric oxide production generation simultaneously.So have to be continuously replenished, to maintain normal physiological function.
This nitric oxide produced in body,In the most each vitals, play an important role.Especially in terms of cardiovascular system, there is the effect of powerful lax vascular smooth muscle, it can increase CBF, prevent the deposits such as bad cholesterol from attaching to vascular wall, thus reduce vessel wall thickening, reduce the chance of blood vessel blockage, simultaneously, maintain healthy blood pressure, effectively alleviate heart burden, thus play the effect that prevention cardio-cerebral diseases produces；In terms of immune system, nitric oxide, is the effective weapon tackling the pathogen such as bacterium, virus, tumour cell, and it can kill multiple pathogens and protect body, is provided that a strong internal system of defense；In terms of nervous system, as the transmission material of a kind of nerve signal, the CBF of brain can be promoted, and may be closely related with the learning and memory process of the growth of brain cell, brain cell.Nitric oxide is also relevant with the secretion of oxytocins to pituitary hormone such as vasopressing.Protection brain cell being avoided adjust brain blood supply during attack and the cerebral ischemia of poisonous substance and should wait relevant, nitric oxide also has the function strengthening cranial nerve cell storage with recalling to information, the cerebral function of maintaining healthy, improves mental definition.
Scientist confirms that nitric oxide can postpone the arriving of female menopausal, scientist also demonstrates that, the property function of man and nitric oxide have substantial connection, the corpora cavernosa penis blood vessel because nitric oxide can relax, so blood circulation can pour cavernous body capilary, in " congestive state ", and make telotism；Cow-bezoar has removing free radical, reduces bad cholesterol in the endovascular accumulation of genitals, thus the smooth entrance of blood in ensureing genitals；This function, coordinates with nitric oxide, has the function superposition of mystery.
Co-Q10, VC, VE, OPC, grape seed extract, Ganodenna Lucidum P.E, hawthorn flavone extract, ginkgo biloba extract, Astragalus Root P.E, bata-carotene, lipoic acid, folic acid, Organic Selenium are all natural antioxidants; interior free yl removed by auxiliary cow-bezoar; reduce the generation of low-density lipoprotein; the vitals such as the protection heart, brain, kidney, pancreas, prostate, prevention and cure of cardiovascular disease, anti-aging, antitumor, lifting immunologic function.Therefore with cow-bezoar and nitric oxide compatibility, also have certain to act synergistically.
Detailed description of the invention
The present invention provides a kind of with cow-bezoar with the health products of nitric oxide compatibility, and the weight proportion of every 10 grams of its health products is: cow-bezoar 100-1500 milligram, L-arginine 1500-3000 milligram, Cit 1500-3000 milligram, taurine 500-2000 milligram.
Wherein, a kind of indispensable composition of the health caring product prescription with cow-bezoar and nitric oxide compatibility in Co-Q10, VC, VE, OPC, grape seed extract, Ganodenna Lucidum P.E, hawthorn flavone extract, ginkgo biloba extract, Astragalus Root P.E, bata-carotene, lipoic acid, folic acid, Organic Selenium non-invention, and mainly need to add in formula according to actual conditions.
Embodiment one
A kind of with cow-bezoar with the health products of nitric oxide compatibility, the weight proportion of every 10 grams of its health products is: cow-bezoar 1000 milligrams, L-arginine 2000 milligrams, Cit 2000 milligrams, taurine 1000 milligrams.
Preparation method is as follows:
Step 1.1, select materials, weigh the raw material of suitable requirement, cow-bezoar 1000 milligrams, L-arginine 2000 milligrams, Cit 2000 milligrams, taurine 1000 milligrams according to certain mass standard；
Step 1.2, mixing, mix the raw material weighed in step 1.1 under 0～20 degree Celsius；
Step 1.3, pulverizing, pulverized 80 mesh sieves by the raw material mixed in step 1.2 by pulverizer；
Step 1.4, preparation, the powder stock after sieving in step 1.3 is respectively prepared capsule, pill, tablet according to conventional formulation method, makes finished product；
Step 1.5, sterilizing, the CO of the finished product 6KGY that step 1.4 is made60Irradiation sterilization；
Production environment cleanliness factor 100,000 grades.
The preparation method of above-mentioned capsule is: is loaded by powder stock in hungry area softgel shell, i.e. makes capsule.
The preparation method of above-mentioned pill is: mixed by powder stock, with refined honey and even, rubbing, through pellet processing machine pill pill.
The preparation method of above-mentioned tablet is: powder stock adds starch 650mg, microcrystalline cellulose 220mg, pelletizes, dries, whole grain, tabletting machine, i.e. piece agent.
Embodiment two
A kind of with cow-bezoar with the health products of nitric oxide compatibility, the weight proportion of every 10 grams of its health products is: cow-bezoar 800 milligrams, L-arginine 1500 milligrams, Cit 1500 milligrams, taurine 1000 milligrams, Co-Q10 200 milligrams, VC 400 milligrams, VE 300 milligrams, OPC 50 milligrams, grape seed extract 120 milligrams, Ganodenna Lucidum P.E 250 milligrams, hawthorn flavone extract 120 milligrams, ginkgo biloba extract 120 milligrams, Astragalus Root P.E 80 milligrams, bata-carotene 25 milligrams, lipoic acid 500 milligrams, folic acid 600 microgram, selenium 80 microgram.
Preparation method is as follows:
Step 2.1, select materials; the raw material of suitable requirement, cow-bezoar 800 milligrams, L-arginine 1500 milligrams, Cit 1500 milligrams, taurine 1000 milligrams, Co-Q10 200 milligrams, VC 400 milligrams, VE 300 milligrams, OPC 50 milligrams, grape seed extract 120 milligrams, Ganodenna Lucidum P.E 250 milligrams, hawthorn flavone extract 120 milligrams, ginkgo biloba extract 120 milligrams, Astragalus Root P.E 80 milligrams, bata-carotene 25 milligrams, lipoic acid 500 milligrams, folic acid 600 microgram, selenium 80 microgram is weighed according to certain mass standard；
Step 2.2, mixing, mix the raw material weighed in step 2.1 under 0～20 degree Celsius；
Step 2.3, pulverizing, pulverized 80 mesh sieves by the raw material mixed in step 2.2 by pulverizer；
Step 2.4, preparation, the powder stock after sieving in step 2.3 is respectively prepared capsule, pill, tablet according to conventional formulation method, makes finished product；
Step 2.5, sterilizing, the CO of the finished product 6KGY that step 2.4 is made60Irradiation sterilization；
Production environment cleanliness factor 100,000 grades.
The preparation method of above-mentioned capsule is: is loaded by powder stock in hungry area softgel shell, i.e. makes capsule.
The preparation method of above-mentioned pill is: mixed by powder stock, with refined honey and even, rubbing, through pellet processing machine pill pill.
The preparation method of above-mentioned tablet is: powder stock adds starch 650mg, microcrystalline cellulose 220mg, pelletizes, dries, whole grain, tabletting machine, i.e. piece agent.
A kind of health products instructions of taking with cow-bezoar and nitric oxide compatibility of the present invention is:
Capsule, takes twice every day, the most once, each takes 2, and the quality control of every seed lac capsule is at 0.4-0.5g；
Pill, takes twice every day, the most once, each takes 2, and the quality control of every pill is at 0.4-0.5g；
Tablet, takes twice every day, the most once, each takes 2, and the quality control of every tablet is at 0.4-0.5g.
Note: needed raw material of the present invention the most all can be bought.
Experimental data:
Experimental example 1: man 82 years old, B ultrasonic is looked into as prostate enlargement, asexual reaction.Taking product of the present invention after 18 months, after B ultrasonic check, prostate is normal, starts sexual reaction, is satisfied with sexuality.
Experimental example 2: man 81 years old, self-induction heart portion is uncomfortable, and firmly hospital looks into electrocardiogram and is shown as heartbeat 50 beats/min, left bundle branch block, and asexual reaction.Take product of the present invention after 90 days, be not in the mood for portion uncomfortable, look into that electrocardiogram is shown as heartbeat 65 beats/min, left bundle branch block disappears；Take product of the present invention sexual reaction after 120 days, take product of the present invention and be satisfied with sexuality after 160 days.
Experimental example 3: man 56 years old, diabetes, blood sugar 9.5, the most asexual requirement.Take product of the present invention after 60 days, blood sugar 5.5, start sexual requirement；Take product of the present invention after 120 days, have satisfied sexuality.
Experimental example 4: female 55 years old, cerebral infarction, action slightly inconvenience, amenorrhea.Taking product of the present invention after 60 days, action, without inconvenience, begins with menstruation.
Experimental example 5: female 56 years old, old and feeble, lassitude, amenorrhea.Take product of the present invention 2 years, have menstruation the most on time, and complexion takes a turn for the better.
Experimental example 6: female 37 years old, menstruation cuts in and out, sexual life insentience.Take product of the present invention after 60 days, begin with sensation；Take product of the present invention after 120 days, feel good, have repeatedly climax.
Claims (6)
1. one kind with cow-bezoar and the health products of nitric oxide compatibility, it is characterised in that the weight proportion of every 10 grams of described health products is: cow-bezoar 100-1500 milligram, L-arginine 1500-3000 milligram, Cit 1500-3000 milligram, taurine 500-2000 milligram.
nullThe most according to claim 1 a kind of with cow-bezoar with the health products of nitric oxide compatibility，It is characterized in that，The weight proportion of every 10 grams of described health products is: cow-bezoar 100-1500 milligram、L-arginine 1500-3000 milligram、Cit 1500-3000 milligram、Taurine 500-2000 milligram、Co-Q10 150-250 milligram、VC 350-500 milligram、VE 200-400 milligram、OPC 40-90 milligram、Grape seed extract 100-150 milligram、Ganodenna Lucidum P.E 200-300 milligram、Hawthorn flavone extract 100-150 milligram、Ginkgo biloba extract 100-150 milligram、Astragalus Root P.E 10-100 milligram、Bata-carotene 20-30 milligram、Lipoic acid 500-600 milligram、Folic acid 600-800 microgram、Organic Selenium 80-100 microgram.
3. one kind with the health products preparation method of cow-bezoar and nitric oxide compatibility, it is characterised in that described health products are prepared by following method:
Select materials, weigh the raw material of suitable requirement according to certain mass standard；
Mixing, mixes above-mentioned weighed raw material under 0～20 degree Celsius；
Pulverize, the above-mentioned raw material mixed was pulverized 80 mesh sieves by pulverizer；
Preparation, is respectively prepared capsule, pill, tablet by the powder stock after above-mentioned sieving according to conventional formulation method, makes finished product；
Sterilizing, the CO of finished product 6KGY60Irradiation sterilization；
Production environment cleanliness factor 100,000 grades.
A kind of health products preparation method with cow-bezoar and nitric oxide compatibility the most according to claim 3; it is characterized in that; wherein said capsule is prepared by following method: powder stock claim 3 prepared loads in hungry area softgel shell, i.e. makes capsule.
A kind of health products preparation method with cow-bezoar and nitric oxide compatibility the most according to claim 3; it is characterized in that, wherein said pill is prepared by following method: powder stock mixing claim 3 prepared, with refined honey and even; rubbing, through pellet processing machine pill pill.
A kind of health products preparation method with cow-bezoar and nitric oxide compatibility the most according to claim 3; it is characterized in that; wherein said tablet is prepared by following method: powder stock claim 3 prepared adds adhesive; granulation, drying, whole grain, tabletting machine, i.e. piece agent.
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