CN105853531A - Traditional Chinese medicine composition for preventing and treating recurrent diseases of sheep in autumn, as well as preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for preventing and treating recurrent diseases of sheep in autumn, as well as preparation method and application thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- General Health & Medical Sciences (AREA)
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Abstract
The invention relates to the technical field of traditional Chinese veterinary medicines, and particularly relates to a traditional Chinese medicine composition for preventing and treating recurrent diseases of sheep in autumn, as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from radix isatidis, semen lepidii, folium eriobotryae and licorice roots. The composition belongs to the prescription of pure traditional Chinese medicines, is safe and effective, has the advantages of low cost, easily available materials, simple processing, no toxic or side effect and the like, and has a remarkable prevention effect on autumn incident diseases, bronchitis, pneumonia, gastroenteritis, forestomach obstruction, stomatitis, sore mouth disease, viral encephalitis, infectious conjunctivitis, pleurisy, dyspepsia and other diseases. Furthermore, after the traditional Chinese medicine composition is taken, residue and hazard of chemical drugs can be reduced even avoided, development of health cultivation of sheep can be promoted, and healthy and harmless products are provided to people. The traditional Chinese medicine composition has a remarkable social significance.
Description
Technical field
The present invention relates to traditional Chinese veterinary medicine technical field, prevent and treat sheep often send out in disease autumn particularly to a kind of
Drug composition and its preparation method and application.
Background technology
Autumn Climate is changeable, and day and night temperature changes greatly, is that sheep respiratory system and digestive system disease etc. are common
Sick multiple season.The sheep of all ages and classes and sex is susceptible to various disease.Sheep often sends out disease bag autumn
Include influenza, bronchitis, pneumonia, gastroenteritis, glandular stomach obstruction, stomatitis, sore mouth virus, viral encephalitis,
Infectious conjunctivitis, pleuritis, dyspepsia, sheep braxy, cud air-blowing and other regular incidence.
Often sending out disease autumn for sheep, treatment is usually based on symptomatic treatment, selects antibiotics, dimension
Raw element class, antipyretic-antalgic and Chinese herbal treatment.For the prevention of sheep multiple disease in autumn, be mostly for
Sheep incidental disease in autumn is prevented and treated:
Such as sheep braxy, this disease, to put prevention first, is inoculated with sheep trigeminy vaccine.Wet Seedling annual spring and autumn 2 times,
Annual 1 time of sub-Seedling.Sheep is advisable with drylot feeding, eats by mistake by pathogen contamination feedstuff and drinking-water when preventing from herding.Note
Warming ventilation in house, feedstuff gradually to complete when changing, and changes the most suddenly.Treatment can intramuscular injection
Blue or green toxin each 80-160 ten thousand unit, initial dose doubles, and three times a day, is used in conjunction 3～4 days.Or sulfanilamide for oral administration
Narrow 0.2 g kg body weight, within the 2nd day, halve, be used in conjunction 3～4 days.
Such as flu, following several prescription can be taked to treat: each 9 grams of Folium Perillae, Rhizoma Zingiberis Recens, onion 2,
It is decocted in water for oral dose；9 grams of Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM 5 grams, Rhizoma Zingiberis powder 2 grams, white sugar 25 grams, grind boiled water into powder and take after mixing it with water；Rhizoma Atractylodis 10
Gram, Herba Schizonepetae, Radix Saposhnikoviae, each 9 grams of Rhizoma Cyperi, each 5 grams of blending, Rhizoma Pinelliae Preparata, chop up and add decocting juice, for oral administration；Herba Alii fistulosi
In vain, each 10 grams of Pericarpium Citri Reticulatae, be decocted in water for oral dose；Herba Ephedrae 15～20 grams, Ramulus Cinnamomi 15～20 grams, Radix Glycyrrhizae 5～10 grams, decoct soup,
Time temperature gavages；Flos Lonicerae 25～30 grams, Fructus Forsythiae, Herba Schizonepetae, each 15～20 grams of Herba Menthae, Fructus Arctii, Semen Sojae Preparatum
Each 10～20 grams, Rhizoma Phragmitis 25 grams, pan-fried soup, time temperature gavage.
Such as dyspepsia, following prescription can be taked to treat: 30 grams of Fructus Hordei Germinatus, Fructus Crataegi (charcoal) 15 grams, sweet number of tracks
(snuggling up to Huang), parching to brown is ground into powder altogether, and every day feeds 3 times, each 1 spoon, serve on 3 days；2040 grams of Natrii Sulfas, compound recipe dragon
Gallbladder joins 1530 milliliters, and vomiting nut is joined 1 milliliter and adds appropriate water mixing, and llama is disposably taken orally, and lamb is cut down according to the circumstance；
Massa Medicata Fermentata 15 grams, 15 grams of Fructus Hordei Germinatus, mountain inspection 15 grams, Radix Et Rhizoma Rhei 7.5 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Pericarpium Citri Reticulatae 15 grams, Fructus Alpiniae Oxyphyllae
12.5 grams, Fructus Amomi 12.5 grams, grind to the powder, 25 kg body weight sheep are divided 2 times and feed.
But, often send out disease autumn for multiple sheep and there is the medicine of general prevention effect and method does not almost have
Have.Accordingly, it is desirable to provide a kind of sheep often sends out the medicine of disease general prevention autumn.
Summary of the invention
In view of this, the invention provides and a kind of prevent and treat sheep and often send out Chinese medicine composition and the system thereof of disease autumn
Preparation Method and application.This Chinese medicine composition can effectively be prevented and treated sheep and often send out disease autumn.
In order to realize foregoing invention purpose, the present invention provides techniques below scheme:
The invention provides a kind of Chinese medicine composition, including Radix Isatidis, Semen Lepidii (Semen Descurainiae), Folium Eriobotryae and Radix Glycyrrhizae.
In traditional Chinese veterinary medicine, autumn, master was dry, and climate variability；Lung being a delicate viscus, is easily invaded by heresy.Therefore autumn is many
There is lung meridian disease.By Chinese herb prevention sheep commonly encountered diseases in autumn, there is safety, curative effect secondary work lasting, nontoxic
With, be not likely to produce drug resistance, low cost, the advantage such as easy to use.
Radix Isatidis, another name: indigo-blue, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root, Radix Clerodenri Cyrtophylli, for cruciferae isatis be dried
Root, excavates the most in the fall, can be used as medicine after the process of preparing Chinese medicine.It is cold in nature, and taste is the most micro-sweet rear pained, has
Heat-clearing and toxic substances removing, preventing cold, effect of sore-throat relieving.It is mainly used in treating maculae caused by violent heat pathogen, crimson tongue purple dark, rotten
The diseases such as larynx scarlet fever.
Semen Lepidii, another name: Ding Li, big suitable, big room, annual or biennial herb, for open country weeds.
Seed is used as medicine, and claims " Semen Lepidii (Semen Descurainiae) ", and cold in nature, bitter in the mouth is pungent, and function includes: eliminating the pathogens from the lung, Hang Shui, expectorant, Dingchuan.
Semen Lepidii (Semen Descurainiae) head sees " herbal classic ", function eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For Brassicaceae Chinese jujube Lung Soup,
In the prescriptions such as own green pepper Li Huang ball, big sunken chest ball.
Folium Eriobotryae is the leaf of rosaceous plant Folium Eriobotryae, has another name called Ba Ye, Lu Juye, its cold nature, bitter in the mouth,
Have effect of clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI, be usually used in treat cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting,
The diseases such as dysphoria with smothery sensation is thirsty.
Radix Glycyrrhizae, another name: state is old, Herba Hedyotis cantonensis, Glycyrrhiza uralensis Fisch., sweet root, pulse family, Glycyrrhiza are perennial
Draft, root is sturdy with root stock, is a kind of tonification Chinese herbal medicine.Medicinal part is root and rhizome.Function master
Control heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc..
Radix Isatidis, Semen Lepidii (Semen Descurainiae), Folium Eriobotryae and Radix Glycyrrhizae with the use of rear, can effectively be prevented multiple by the present invention
Sheep often sends out disease autumn, greatly reduces sickness rate and the mortality rate of sheep in autumn, hence it is evident that improve the life of sheep
Produce performance.Compared to single dose, the compound recipe that the present invention provides has more preferable prevention effect.
We moisturize with reason lung and are good at, and cure mainly cough with asthma nose pus etc., close season very much.Can effectively prevent the sheep autumn
Season regular incidence, reduce economic loss, and safe noresidue, with low cost, raw material is easy to get, user
Just, easily popularizing, popularizing application prospect is wide.
As preferably, in parts by weight, this Chinese medicine composition includes:
In the embodiment that the present invention provides, in parts by weight, this Chinese medicine composition includes:
Present invention also offers this Chinese medicine composition and often send out disease medicament autumn in preparation prevention and/or treatment sheep
In application.
In the present invention, sheep often sends out disease autumn is influenza, bronchitis, pneumonia, gastroenteritis, glandular stomach
Obstruction, stomatitis, aphtha, viral encephalitis, infectious conjunctivitis, pleuritis, dyspepsia, sheep are fast
One or more in epidemic disease or cud air-blowing.
Present invention also offers the preparation method of this Chinese medicine composition, including: by Radix Isatidis, Semen Lepidii (Semen Descurainiae),
Folium Eriobotryae and Radix Glycyrrhizae are pulverized, mixing.
As preferably, the fineness of pulverizing is 80 mesh.
Present invention also offers a kind of medicine, including the Chinese medicine composition of the present invention.
Present invention also offers a kind of feedstuff, including the Chinese medicine composition of the present invention.
In the embodiment that the present invention provides, the using method of the Chinese medicine composition of the present invention is 2%～3% to mix
Material, or one time 20～30g, once a day, be used in conjunction 5～7 days.
As preferably, the Chinese medicine composition of the present invention weight/mass percentage composition in feedstuff is 2%～3%.
Present invention also offers a kind of feed additive, including the Chinese medicine composition of the present invention.
The invention provides a kind of prevent and treat sheep often Chinese medicine composition sending out disease in autumn and preparation method thereof and should
With.This Chinese medicine composition includes Radix Isatidis, Semen Lepidii (Semen Descurainiae), Folium Eriobotryae and Radix Glycyrrhizae.The present invention has to be had as follows
Benefit effect:
The invention belongs to pure Chinese medicine formula, have safely and effectively, reduce cost, draw materials easily, processing letter
Just, the advantage such as have no side effect, sheep is easily occurred autumn influenza, bronchitis, pneumonia, gastroenteritis,
Glandular stomach obstruction, stomatitis, aphtha, viral encephalitis, infectious conjunctivitis, pleuritis, dyspepsia with
And other diseases etc. is respectively provided with significant preventive effect, use energy after the Chinese medicine composition of the present invention simultaneously
Residual and the harm of chemicals is even avoided in enough minimizings, promotes the development of sheep healthy aquaculture, carries for people
For healthy harmless product, there is significant social meaning；
Chinese medicine composition of the present invention is added in feedstuff and feeds sheep, the production performance of sheep is affected relatively big, energy
Enough dramatically increase average daily gain, significantly reduce feed-weight ratio, increase the economic benefit of cultivation.
Detailed description of the invention
The invention discloses a kind of prevent and treat sheep often Chinese medicine composition sending out disease in autumn and preparation method thereof and should
With, those skilled in the art can use for reference present disclosure, is suitably modified technological parameter and realizes.Need especially
It is noted that all similar replacements and change apparent to those skilled in the art, it
Be considered as being included in the present invention.Method and the application of the present invention are carried out by preferred embodiment
Describing, related personnel substantially can be to side as herein described in without departing from present invention, spirit and scope
Method and application are modified or suitably change and combine, and realize and apply the technology of the present invention.
In preventing and treating sheep often Chinese medicine composition sending out disease in autumn that the present invention provides and its preparation method and application
Raw materials used medicine all can be buied by market.
Below in conjunction with embodiment, the present invention it is expanded on further:
The preparation of embodiment 1 Chinese medicine composition
The present embodiment Chinese medicine composition includes (in parts by weight):
Preparation method: pulverized respectively by the Chinese medicine of above-mentioned weight portion, sieves through 80 mesh, mix homogeneously.
Embodiment 2 feeding experiment
Test and carry out 15 days-November 15 August in 2015, by have selected 360 at Xingtai Yang Chang
Only 3 monthly age Small-fat-tail sheep, are randomly divided into 6 groups, often group 60:
1st group is matched group, without medicine；
2nd group is Radix Isatidis single dose group, adds Radix Isatidis；
3rd group is Semen Lepidii (Semen Descurainiae) single dose group, adds Semen Lepidii (Semen Descurainiae)；
4th group is Folium Eriobotryae single dose group, adds Folium Eriobotryae；
5th group is Radix Glycyrrhizae single dose group, adds Radix Glycyrrhizae；
6th group is embodiment 1 group, adds embodiment 1 Chinese medicine composition.
Chinese medicine in 2nd group to the 6th group all by 3% interpolation of concentrate, every day 1 time, is used in conjunction 5 days.Often
The feed consumption rate that it meter record is often organized, off-test is weighed, and calculates average feed consumption rate, average daily gain and material weight
Ratio.Record incidence and death condition, calculate M & M.
The results are shown in Table 1 and table 2.
Table 1 adds the different Chinese herbal medicine impact on Productive Performance of Sheep autumn
Note: representing that difference is extremely notable (P < 0.01) with column data shoulder mark upper and lower case letter difference, capitalization is identical, lower case
Containing same letter, different expressions significant difference (P<0.05), represent that difference is notable (P>0.05).
From table 1, average feed consumption rate, average daily gain and feed-weight ratio, without Chinese herbal medicine group with add
Add and compare between 4 groups of single medicinal material, significant difference (P < 0.05)；Add and compare between single medicinal material 4 groups
Relatively difference is notable (P > 0.05), add embodiment 1 group with without group and add single medicinal material 4 groups it
Between compare, difference is extremely notable (P < 0.01).Result illustrates, adds the Chinese medicine of the embodiment of the present invention 1
The production performance of sheep is affected bigger by compositions, it is possible to dramatically increase average daily gain, significantly reduces material weight
Ratio, increases the economic benefit of cultivation.
Table 2 adds different Chinese herbal medicine impact pathogenetic on sheep disease autumn
| Group | Adding proportion/% | Sickness rate/% | Mortality rate/% |
| Matched group | 3 | 18 | 3 |
| Radix Isatidis single dose group | 3 | 10 | 1 |
| Semen Lepidii (Semen Descurainiae) single dose group | 3 | 2 | 0 |
| Folium Eriobotryae single dose group | 3 | 5 | 0 |
| Radix Glycyrrhizae single dose group | 3 | 2 | 0 |
| Embodiment 1 group | 3 | 1 | 0 |
From table 2, add the embodiment of the present invention 1 Chinese medicine composition and can significantly reduce sickness rate, than
Being not added with Chinese herbal medicine group sickness rate and reduce 17% respectively, mortality rate reduces 3%, than single Chinese herbal medicine 4
Group M & M all decreases.Illustrate that the Chinese medicine composition adding the embodiment of the present invention 1 is to sheep
There is obvious functions of prevention and health care in the fall, the M & M of sheep can be reduced, for sheep husbandry
Escort.
Embodiment 3 feeding experiment
Experimental animal: Xingtai Yang Chang have selected 400 3 monthly age Small-fat-tail sheep；
Test packet and medication: be randomly divided into 4 groups, often group 100,1-4 group is added in concentrate
The ratio of embodiment 1 Chinese medicine composition is respectively 0%, 1%, 2%, 3%, feeding time 2015 8
15-November 15 moon.
The feed consumption rate that every day, meter record was often organized, off-test is weighed, and calculates average feed consumption rate, average daily gain
And feed-weight ratio.Record incidence and death condition, calculate M & M.
The results are shown in Table 3,4.
The different adding proportion Chinese medicine composition impact on Productive Performance of Sheep of table 3
Note: representing that difference is extremely notable (P < 0.01) with column data shoulder mark upper and lower case letter difference, capitalization is identical, lower case
Containing same letter, different expressions significant difference (P<0.05), represent that difference is notable (P>0.05).
From table 3, average feed consumption rate, average daily gain and feed-weight ratio, without Chinese herbal medicine group and 1%
Comparing between Chinese herbal medicine group, difference is not notable (P > 0.05)；Add between 2% and 3% Chinese herbal medicine group
Comparing difference is notable (P > 0.05), adds 2%, 3% Chinese herbal medicine group and without Chinese herbal medicine group and 1%
Comparing between Chinese herbal medicine group, difference is extremely notable (P < 0.01).Result illustrates, adds 2%, 3% medium-height grass
The production performance of sheep is affected bigger by medicine group, it is possible to dramatically increases average daily gain, significantly reduces feed-weight ratio,
Increase the economic benefit of cultivation.
The different adding proportion Chinese medicine composition impact pathogenetic on sheep disease of table 4
| Adding proportion/% | Sickness rate/% | Mortality rate/% |
| 0 | 18 | 3 |
| 1 | 10 | 1 |
| 2 | 2 | 0 |
| 3 | 1 | 0 |
From table 4, add 2% and 3% Chinese herbal medicine group and can significantly reduce sickness rate, add 2% He
3% Chinese herbal medicine ratio is not added with Chinese herbal medicine group sickness rate and reduces 16%, 17% respectively, and mortality rate all reduces 3%,
Reducing 8%, 9% respectively than adding 1% Chinese herbal medicine group sickness rate, mortality rate all reduces 1%.Explanation
Add 2% and 3% Chinese herbal medicine and sheep is had in the fall obvious functions of prevention and health care, sending out of sheep can be reduced
Sick rate and mortality rate, escort for sheep husbandry.
Embodiment 4 application example
From 2010 to 2015 years 6 years in Xingtai, Baoding, Hengshui, sheep raising field, Shijiazhuang statistics autumn
Taking embodiment 1 Chinese medicine composition to sheep disease prevention effect (feeding method is with embodiment 2), result is such as
Following table.
Autumn taken Chinese medicine composition to sheep disease prevention effect observation table by table 5
From table 5 result of the test, sheep is often sent out disease and have the most pre-autumn by Chinese medicine composition of the present invention
Anti-effect.
The above is only the preferred embodiment of the present invention, it is noted that general for the art
For logical technical staff, under the premise without departing from the principles of the invention, it is also possible to make some improvement and profit
Decorations, these improvements and modifications also should be regarded as protection scope of the present invention.
Claims (10)
1. a Chinese medicine composition, it is characterised in that include Radix Isatidis, Semen Lepidii (Semen Descurainiae), Folium Eriobotryae and Radix Glycyrrhizae.
Chinese medicine composition the most according to claim 1, it is characterised in that in parts by weight, described
Chinese medicine composition includes:
Chinese medicine composition the most according to claim 1 and 2, it is characterised in that in parts by weight,
Described Chinese medicine composition includes:
4. as according to any one of claims 1 to 3, Chinese medicine composition in preparation prevention and/or treats the sheep autumn
Application in Ji Changfa disease medicament.
Application the most according to claim 4, it is characterised in that described sheep often sends out disease for stream autumn
Sense, bronchitis, pneumonia, gastroenteritis, glandular stomach obstruction, stomatitis, aphtha, viral encephalitis, infection
One or more in membranous conjunctivitis, pleuritis, dyspepsia, sheep braxy or cud air-blowing.
6. the preparation method of Chinese medicine composition as according to any one of claims 1 to 3, it is characterised in that
Including: Radix Isatidis, Semen Lepidii (Semen Descurainiae), Folium Eriobotryae and Radix Glycyrrhizae are pulverized, mixes.
7. a medicine, it is characterised in that include Chinese medicine composition according to any one of claims 1 to 3
Thing.
8. a feedstuff, it is characterised in that include Chinese medicine composition according to any one of claims 1 to 3
Thing.
Feedstuff the most according to claim 8, it is characterised in that described Chinese medicine composition is raised described
Weight/mass percentage composition in material is 2%～3%.
10. a feed additive, it is characterised in that include according to any one of claims 1 to 3
Chinese medicine composition.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106720989A (en) * | 2016-11-30 | 2017-05-31 | 刘吴阳 | A kind of feed addictive for sheep obstruction of omasum disease |
| CN108450671A (en) * | 2018-03-06 | 2018-08-28 | 张掖市金农源生物科技有限公司 | A kind of feed and preparation method thereof for treating Fattening Sheep pneumonia |
-
2016
- 2016-06-21 CN CN201610450676.XA patent/CN105853531A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106720989A (en) * | 2016-11-30 | 2017-05-31 | 刘吴阳 | A kind of feed addictive for sheep obstruction of omasum disease |
| CN108450671A (en) * | 2018-03-06 | 2018-08-28 | 张掖市金农源生物科技有限公司 | A kind of feed and preparation method thereof for treating Fattening Sheep pneumonia |
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Effective date of registration: 20170120 Address after: Dongmoucun Village Economic Development Zone, Xingtai City, Hebei province Lincheng County 071051 East Applicant after: Hebei animal husbandry Polytron Technologies Inc Address before: Xiangyang Road 071051 Hebei city of Baoding province in the 4-604 District No. 625 Wyatt Applicant before: Gong Sumei |
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Application publication date: 20160817 |