CN105853246A - 包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 - Google Patents
包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 Download PDFInfo
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- CN105853246A CN105853246A CN201610365118.3A CN201610365118A CN105853246A CN 105853246 A CN105853246 A CN 105853246A CN 201610365118 A CN201610365118 A CN 201610365118A CN 105853246 A CN105853246 A CN 105853246A
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- Prior art keywords
- substituted
- ketone
- amino
- methylpyrazole
- methyl
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/415—Aminophenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/51—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
Description
Claims (10)
Applications Claiming Priority (3)
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US17087209P | 2009-04-20 | 2009-04-20 | |
US61/170,872 | 2009-04-20 | ||
CN2010800174357A CN102405080A (zh) | 2009-04-20 | 2010-04-20 | 包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 |
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CN2010800174357A Division CN102405080A (zh) | 2009-04-20 | 2010-04-20 | 包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 |
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CN105853246A true CN105853246A (zh) | 2016-08-17 |
CN105853246B CN105853246B (zh) | 2019-07-26 |
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CN201610365118.3A Active CN105853246B (zh) | 2009-04-20 | 2010-04-20 | 包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 |
CN2010800174357A Pending CN102405080A (zh) | 2009-04-20 | 2010-04-20 | 包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 |
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CN2010800174357A Pending CN102405080A (zh) | 2009-04-20 | 2010-04-20 | 包含自由基清除剂和螯合剂的角蛋白染色组合物及其用途 |
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US (1) | US7985266B2 (zh) |
EP (1) | EP2421613A2 (zh) |
JP (1) | JP5587979B2 (zh) |
CN (2) | CN105853246B (zh) |
AU (1) | AU2010239440A1 (zh) |
BR (1) | BRPI1014597A2 (zh) |
CA (1) | CA2758013C (zh) |
MX (1) | MX2011011056A (zh) |
WO (1) | WO2010123866A2 (zh) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2011011057A (es) * | 2009-04-20 | 2011-11-04 | Procter & Gamble | Composiciones de teñido de queratina que comprenden un depurador de radicales y uso de estas. |
TWI447224B (zh) * | 2009-12-25 | 2014-08-01 | Uwiz Technology Co Ltd | 使用於半導體晶圓製造之清洗組成物 |
FR2968946B1 (fr) * | 2010-12-20 | 2013-04-19 | Oreal | Procede de coloration de fibres keratiniques a partir de derives du resorcinol, de sels de sulfate, d'agents oxydant et d'agent alcalinisant |
DE102011110100A1 (de) * | 2011-08-12 | 2013-02-14 | Evonik Goldschmidt Gmbh | Verfahren zu Herstellungen von Polysiloxanen mit stickstoffhaltigen Gruppen |
MX364254B (es) | 2012-03-27 | 2019-04-17 | Noxell Corp | Composiciones colorantes de cabello que comprenden 3-amino-2,6-dimetilfenol, métodos y estuches que comprenden las composiciones. |
MX345233B (es) | 2012-03-27 | 2016-12-02 | Noxell Corp | Composiciones colorantes para el cabello que comprenden amino-2,6-dimetilfenol y reveladores tipo 1,4-fenilendiamina, metodos y estuches que comprenden las composiciones. |
WO2014004459A2 (en) | 2012-06-25 | 2014-01-03 | The Procter & Gamble Company | Hair colorant compositions comprising 2-methoxymethyl-1,4-diaminobenzene and 2,6-dihydroxyethylaminotoluene, methods, and kits comprising the compositions |
CN104768916B (zh) | 2012-10-26 | 2018-11-27 | 诺赛尔股份有限公司 | 制备2-甲氧基甲基-1,4-苯二胺及其盐的方法 |
CN104768917A (zh) | 2012-10-26 | 2015-07-08 | 宝洁公司 | 制备2-甲氧基甲基-1,4-苯二胺及其盐的方法 |
KR101446184B1 (ko) | 2013-02-12 | 2014-10-02 | 에스엘아이 프로덕션 코퍼레이션 | 가발을 구성하는 인모의 다양한 특성을 균일한 물성으로 변환시키기 위한 펌제의 이용방법 |
US9242123B2 (en) * | 2013-05-16 | 2016-01-26 | The Procter & Gamble Company | Hair thickening compositions and methods of use |
EP2926802B1 (en) | 2014-04-02 | 2017-09-27 | Noxell Corporation | Hair colouring compositions, kits, method, and use thereof |
MX2017005808A (es) | 2014-11-04 | 2017-08-02 | Noxell Corp | Procedimiento para la preparacion de 1,4-bencenodiaminas 2-sustituidas y sales de las mismas. |
US9688609B2 (en) | 2014-11-04 | 2017-06-27 | Noxell Corporation | Telescoping synthesis of 2-methoxymethyl-P-phenylenediamine |
MX361963B (es) | 2014-11-04 | 2018-12-19 | Noxell Corp | Colorantes azoicos directos y método para teñir el pelo usando estos colorantes. |
US9695109B2 (en) | 2014-11-04 | 2017-07-04 | Noxell Corporation | Telescoping synthesis of 2-methoxymethyl-p-phenylenediamine |
FR3029107B1 (fr) * | 2014-11-27 | 2018-02-02 | L'oreal | Composition de coloration comprenant au moins un coupleur 2-aminoimidazole particulier et une base d'oxydation, procedes et dispositifs |
US9889080B2 (en) | 2015-05-07 | 2018-02-13 | Celeb LLC | Color depositing shampoo |
US10245221B2 (en) | 2015-05-07 | 2019-04-02 | Celeb LLC | Stabilized color depositing shampoo |
JP7345152B2 (ja) | 2016-05-25 | 2023-09-15 | ホーユー株式会社 | 酸化染毛剤組成物セット |
CN112512491A (zh) | 2018-09-04 | 2021-03-16 | 昂高知识产权有限公司 | 蛋白质底物的染色方法 |
DE102018222222A1 (de) * | 2018-12-19 | 2020-06-25 | Henkel Ag & Co. Kgaa | Oxidationsfärbemittel in Rotnuancen mit verringerter Farbverschiebung durch Kupferionen |
CN114555483B (zh) | 2019-10-14 | 2024-04-26 | 宝洁公司 | 含有固体制品的可生物降解的和/或家庭可堆肥的小袋 |
WO2023245463A1 (en) * | 2022-06-21 | 2023-12-28 | L'oreal | A stabilized composition comprising a thiopyridinone compound and chelating agent |
FR3140276A1 (fr) * | 2022-09-30 | 2024-04-05 | L'oreal | Composition cosmétique de soin des cheveux comprenant des tensioactifs anioniques particuliers et des silicones aminées particulières, et procédé de traitement cosmétique des cheveux. |
FR3140271A1 (fr) * | 2022-09-30 | 2024-04-05 | L'oreal | Composition cosmétique de soin des cheveux comprenant des tensioactifs anioniques et/ou amphotères, et des silicones aminées particulières, et procédé de traitement cosmétique des cheveux. |
FR3140281A1 (fr) * | 2022-09-30 | 2024-04-05 | L'oreal | Procédé de traitement cosmétique des cheveux avec une composition cosmétique comprenant des silicones aminées particulières |
FR3140274A1 (fr) * | 2022-09-30 | 2024-04-05 | L'oreal | Composition cosmétique de soin des cheveux comprenant au moins une silicone aminée particulière et au moins un agent épaississant |
FR3140277A1 (fr) * | 2022-09-30 | 2024-04-05 | L'oreal | Composition cosmétique de soin des cheveux comprenant au moins une silicone aminée particulière et au moins un polymère associatif, et procédé de traitement cosmétique des cheveux |
FR3140273A1 (fr) * | 2022-09-30 | 2024-04-05 | L'oreal | Composition cosmétique de soin des cheveux comprenant au moins une silicone aminée particulière et au moins un agent colorant et/ou un azurant optique, et procédé de traitement cosmétique des cheveux |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030131423A1 (en) * | 2001-03-01 | 2003-07-17 | Manuela Javet | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1422838A (fr) * | 1964-02-04 | 1966-01-03 | Oreal | Composition nouvelle pour la teinture des cheveux à l'aide de colorants d'oxydation |
FR1426889A (fr) * | 1964-03-02 | 1966-02-04 | Oreal | Nouvelle solution tinctoriale pour cheveux |
AT282072B (de) * | 1968-05-30 | 1970-06-10 | Therachemie Chem Therapeut | Haarfärbemittel |
US4402700A (en) * | 1976-02-09 | 1983-09-06 | Clairol Incorporated | Composition for coloring hair containing an oxidizing agent and certain quaternary amines |
FR2746310B1 (fr) * | 1996-03-22 | 1998-06-12 | Oreal | Compositions de teinture des fibres keratiniques contenant des pyrazolin-3,5-dione ; leur utilisation pour la teinture comme coupleurs, procede de teinture |
US20020035758A1 (en) * | 1997-05-23 | 2002-03-28 | Dominic Pratt | Hair colouring compositions and their use |
DE19745356A1 (de) * | 1997-10-14 | 1999-04-15 | Henkel Kgaa | Verwendung von Oniumaldehyden und -ketonen zum Färben von keratinhaltigen Fasern |
US6074438A (en) * | 1998-03-03 | 2000-06-13 | Bristol-Myers Squibb Co. | Hair dyeing compositions containing 2-chloro- and 2,6-dichloro-4-aminophenol and phenylpyrazolones |
DE19936911A1 (de) * | 1999-08-05 | 2001-02-08 | Henkel Kgaa | Mittel zum Färben von keratinhaltigen Fasern |
DE60216893T2 (de) * | 2001-01-23 | 2007-07-26 | P & G-Clairol, Inc., Cincinnati | Primäres zwischenprodukt für die oxidative haarfärbung |
US20040107516A1 (en) * | 2001-04-05 | 2004-06-10 | The Procter & Gamble Company | Hair colouring compositions and their use |
EP1398020A1 (en) * | 2002-09-16 | 2004-03-17 | Kao Corporation | Hair dye composition comprising an azo dye containing a dissociative proton, method and use |
FR2845283B1 (fr) | 2002-10-04 | 2006-05-05 | Oreal | Composition tinctoriale comprenant au moins une base d'oxydation heterocyclique et au moins un coupleur 2,3-diaminopyridine substitue |
DE10261656A1 (de) * | 2002-12-23 | 2004-07-01 | Henkel Kgaa | Mittel zum Färben von keratinhaltigen Fasern |
DE102005042051A1 (de) | 2005-09-02 | 2007-03-08 | Henkel Kgaa | Verfahren zur Färbung keratinhaltiger Fasern |
MX2011011057A (es) * | 2009-04-20 | 2011-11-04 | Procter & Gamble | Composiciones de teñido de queratina que comprenden un depurador de radicales y uso de estas. |
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- 2010-04-20 AU AU2010239440A patent/AU2010239440A1/en not_active Abandoned
- 2010-04-20 US US12/763,286 patent/US7985266B2/en not_active Expired - Fee Related
- 2010-04-20 JP JP2012506002A patent/JP5587979B2/ja not_active Expired - Fee Related
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US20030131423A1 (en) * | 2001-03-01 | 2003-07-17 | Manuela Javet | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives |
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WO2010123866A2 (en) | 2010-10-28 |
CA2758013A1 (en) | 2010-10-28 |
EP2421613A2 (en) | 2012-02-29 |
CN102405080A (zh) | 2012-04-04 |
BRPI1014597A2 (pt) | 2016-04-05 |
US20110035886A1 (en) | 2011-02-17 |
AU2010239440A1 (en) | 2011-11-10 |
JP2012524081A (ja) | 2012-10-11 |
JP5587979B2 (ja) | 2014-09-10 |
WO2010123866A3 (en) | 2011-08-18 |
CN105853246B (zh) | 2019-07-26 |
MX2011011056A (es) | 2011-11-04 |
US7985266B2 (en) | 2011-07-26 |
CA2758013C (en) | 2014-02-25 |
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