CN105852960B - Gases throttling type cryosurgical device and control method - Google Patents

Gases throttling type cryosurgical device and control method Download PDF

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CN105852960B
CN105852960B CN201610225817.8A CN201610225817A CN105852960B CN 105852960 B CN105852960 B CN 105852960B CN 201610225817 A CN201610225817 A CN 201610225817A CN 105852960 B CN105852960 B CN 105852960B
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pressure
gas
freezer
solenoid valve
rewarming
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CN105852960A (en
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赵国江
李萍
姜骁洋
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天津美电医疗科技有限公司
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Abstract

本发明公开了种气体节流型冷冻外科装置及其控制方法,可以实现多种复温方法:本发明利用从高压冷冻气体中分流和限压至低于其节流工作压力的气体复温(分流复温);利用低于其冷冻工作压力的剩余气体复温(余气复温);利用普通压力气体复温(普压复温);利用节流致热型气体复温(节流复温);利用气源关闭、设备排气过程复温(排气复温)。 The present invention discloses a throttle-type gases cryosurgical apparatus and a control method, various methods may be implemented rewarming: The present invention uses a high-pressure refrigerant gas from the bypass and throttling pressure limiting the operating pressure to below the gas rewarming ( shunt rewarming); using frozen below its operating pressure rewarming residual gas (residual gas rewarming); rewarming using an ordinary gas pressure (pressure P rewarming); pyrogenic type gas by the expansion rewarming (throttle complex temperature); closed by an air source, an exhaust device during rewarming (exhaust rewarming). 本发明也引入气体预热装置,提高复温效率和温度,实现冷冻、复温和加热三种功能。 The present invention is also introduced into the gas preheating means to improve the efficiency and rewarming temperature, to achieve the freezing, heating rewarming three functions. 本发明纠正了节流致冷型气体只能用于冷冻的技术偏见,解决了气体节流型冷冻外科设备的复温难题,提高气体利用率,降低手术成本,节能环保,提升复温性能和增加热疗的功能,有助推动冷冻消融技术的普及和提高。 The present invention corrects throttling type gas refrigerant for freezing technical prejudice can solve the problem of thawing cryosurgical gas type throttle apparatus, improve gas utilization efficiency and reduce operation costs, energy saving, performance and enhance rewarming hyperthermia increased functionality, will help to promote and enhance the popularity cryoablation technology.

Description

一种气体节流型冷冻外科装置及其控制方法 A gas throttling type cryosurgical device and control method

技术领域 FIELD

[0001]本发明涉及冷冻外科治疗的医疗器械,发明了一种气体节流型冷冻外科系统及其控制方法。 [0001] The present invention relates to a cryosurgical treatment of medical device, the invention A gas throttling type cryosurgical system and control method.

背景技术 Background technique

[0002]冷冻外科治疗是利用超低温毁损和消融病变组织的方法,也是人类历史上最早使用的病变组织消融技术。 [0002] Cryosurgery treatment method is the use of ultra-low temperature damage and ablation of diseased tissue, diseased tissue is the earliest history of human use of ablation techniques. 自1960年美国神经外科医生Irving Cooper和工程师Arnold Lee 发明王探针状液氮冷冻器并用于冷冻脑组织后,使用液氮作为低温工质(冷媒)、加热氮气作为高温工质(热媒)的液氮冷冻外科设备被应用于治疗各种肿瘤。 Since 1960 the US neurosurgeon Irving Cooper and engineers Arnold Lee King invention is a probe-like frozen in liquid nitrogen for freezing and brain tissue, using liquid nitrogen as a cryogenic working fluid (refrigerant), heated nitrogen gas as a high temperature working fluid (heat medium) liquid nitrogen cryosurgical apparatus is used in the treatment of various tumors. 但液氮冷冻设备复杂笨重、操作困难和疗效欠佳曾使冷冻外科治疗陷于长期停顿和衰落。 However, frozen in liquid nitrogen complex heavy equipment, operating difficulties and poor efficacy was caught in the frozen surgical treatment and long-term halt the decline.

[0003]自1990年代起,基于焦耳-汤姆逊原理的以氩氦刀为首的气体节流型低温冷冻外科系统的发明和f泛应用,使冷冻外科重新获得医学界的认可,复活了低温冷冻外科治疗技术。 [0003] Since the 1990s, based on the Joule - throttling type gas cryogenic surgical system to cryosurgical Thomson headed the principles of the invention and the Pan-f application, the cryosurgical regained the medical profession, resurrected frozen surgical treatment technology. 比如使用高压氩气冷冻和普压氦气复温的氩氦刀已被肿瘤科、介入科、泌尿外科、胸夕卜科、肝胆外科、呼吸科、消化科等临床科室采用,用于肝癌、肺癌、胰腺癌、前列腺癌、肾肿瘤、骨肿瘤、脑瘤、软组织肿瘤等各种良恶性实体肿瘤的冷冻消融治疗,成为临床普遍应用的肿瘤冷冻消融方法之一。 For example using high pressure argon freezing pressure P and rewarming helium argon helium knife has been oncology, interventional radiology, urology, chest Xi Boke, hepatobiliary surgery, respiratory, gastroenterology and other clinical departments using, for liver cancer, a variety of benign and malignant solid tumors of lung cancer, pancreatic cancer, prostate cancer, renal cancer, bone cancer, brain tumors, soft tissue tumors such as cryoablation therapy, tumor cryoablation to become one of the universal application of the clinical method.

[0004]本发明将低温工质输送到靶组织对其进行冷冻的装置命名为冷冻器。 Means [0004] The present invention is a low temperature working medium delivered to the target tissue to be frozen in the freezer named. 在冷冻外科研究与实践中,冷冻器也称为冷冻探针、冷冻探杆、冷冻探头、冷刀、冷冻球囊、冷冻电极、超冷手术器、cryoprobe、cryot ip 或cryoneedle 等。 In cryosurgical research and practice, also known as freezer cryoprobe, freezing probe, cryoprobe, cold knife, balloon frozen, freeze-electrode ultracold surgical device, cryoprobe, cryot ip, or the like cryoneedle.

[0005]冷冻外科治疗技术需要快速冷冻和复温解冻这两个方面。 [0005] Cryosurgery treatment technology requires rapid freezing and thawing thaw these two aspects. 按照其工作原理和使用的低温工质(冷媒),主要的冷冻方式有: In accordance with its principles and low temperature working fluid (refrigerant) used in the main refrigeration methods are:

[0006] (1)液体气化型:使用低温液体(如液氮等)作为低温工质气化吸热的冷冻方式,如液氮冷冻设备。 [0006] (1) the liquid vaporization type: the use of a cryogenic liquid (e.g., liquid nitrogen) as a low temperature and freeze endothermic gasification refrigerant, such as liquid nitrogen refrigeration equipment. 此种冷冻方式的优点是常见的低温液体很方便取得,且成本低廉。 Advantage of this approach is common in refrigeration cryogenic liquid is easy to obtain, and low cost. 缺点是运输和贮存不方便,设备体积庞大和笨重;低温液体由设备连接管输出至冷冻器过程中,均须绝热层保护,造成管路和冷冻器粗大僵硬;并因冷冻器常有“气堵”需要术中停止和重置设备的问题。 The disadvantage is inconvenient to transport and storage, the volume of bulky and heavy equipment; cryogenic liquid from the device is connected to the output pipe freezer process shall protective insulating layer, resulting in coarse line and a stiff freezer; freezer and because often "Gas blocking "need surgery to stop and reset the equipment problems. 同时,其冷冻起始缓慢和冷冻速率低,造成细胞脱水而影响冷冻效果及局部复发率高的问题。 Meanwhile, the frozen starting slow and low freezing rate, causing cell dehydration and cooling effect and the impact of local recurrence rate.

[0007] (2)气体节流型:利用高压气体的焦耳-汤姆逊节流效应产生低温的冷冻方式,如氩氦刀和其他使用压缩气体作为低温工质的设备。 [0007] (2) Gas throttling type: the use of high pressure gas Joule - Thomson throttling effect produced cryogenic refrigeration means, such as cryosurgery and other compressed gases used as a low temperature working medium device. 其优点是使用常温气体,气体输送管和冷冻器杆不需绝热保护,避免低温冷冻液的喷溅、泄漏和冻伤;可控性佳、操作方便、冷冻速度快、冷冻器直径细。 The advantage is a gas at normal temperature, the gas delivery tube and the rod does not need the heat insulating freezing protection against splashing of cryogenic liquid, and leakage frostbite; good controllability of convenience, operation, frozen fast, small diameter freezer. 其缺点是冷冻气体工作压力高,并因压力下降导致低温工质浪费很大。 The disadvantage is that frozen gas high-pressure work, and because of the low temperature working fluid pressure drops resulting in a great waste. 如氩氦刀通常使用满瓶压力35MPa的40升氩气瓶,冷冻时氩气最低工作压力为20MPa,每瓶只能使用1〜1.5小时,而低于20MPa的氩气节流效果急剧降低,几无冷冻效果。 The cryosurgery generally used full cylinder pressure argon gas cylinder 40 liters of 35MPa, freezing the minimum working pressure of 20MPa argon gas, use only bottle ~ 1.5 hours, and less than 20MPa argon throttle effect is drastically reduced, several no cooling effect. 考虑设备本身分压,气瓶输出压力低于21MPa时,设备输出至冷冻器的压力将低于20MPa,只能废弃。 Consider dividing the device itself, when the output of the cylinder pressure is lower than 21MPa, the output pressure to the device will be lower than 20 MPa or freezer, only discarded. 也即整瓶气体中只有约40%可以利用,60%必须废弃。 I.e. only full bottle of gas may be utilized to about 40%, 60% must be discarded. 这带来极大的生产、运输和使用浪费。 This brings great production, transportation and use of waste.

[0008] 冷冻设备的复温或加热功能是实现现代冷冻外科公认的“冷冻-复温-再冷冻-再复温”双循环治疗方式和从冷冻组织中退出冷冻器所必需的功能。 [0008] The refrigerating or heating device thawing cryosurgical modern functionality is implemented recognized "freeze - thawing - refrozen - rewarming" double cycle treatment and withdrawn from the freezer frozen tissues necessary functions. 按照高温工质(热媒)的种类和方法,主要的复温方式有: According to the high-temperature working fluid (heat medium) and a method of the kind, there is the main rewarming:

[0009] (1)加热的低压气体通入冷冻器,利用热传导,直接加热冷冻器内部,如液氮冷冻设备的复温。 [0009] (1) low pressure heating gas into the freezer, by heat conduction, heat directly inside the freezer, such as a liquid nitrogen freezing apparatus rewarming. 此种复温方式的优点是成本低廉、技术成熟。 Rewarming advantage of this approach is low cost, mature technology. 缺点是液氮设备需要配备额外的气体回收、压缩、贮存和加热装置,体积较大、结构复杂且复温速度较慢。 The disadvantage is equipped with additional devices require nitrogen gas recovery, compression, storage and heating means, bulky, complex and slow rewarming.

[0010] (2)利用置于冷冻器内的电热、射频、微波、激光等产热装置加热复温。 [0010] (2) placed in the freezer using electric, radio frequency, microwave, laser and other heat generating means for heating rewarming. 其优点是不需使用或较少使用气体。 The advantage is that without the use of a gas or less. 其缺点是复温速度较慢;且需要将电流等输入直接接触人体组织、 温度极低的冷冻器内部,产生特殊电击和电磁干扰等风险。 The disadvantage is slow rewarming rate; and the like need to directly input current contact with the body tissue, the risk of low temperature inside the freezer to produce a special shock and electromagnetic interference.

[0011] (3)利用常温下节流效应产热的气体在冷冻器内直接产热,如氩氦刀使用氦气复温(氦气反转温度为40K,常温下节流膨胀放热)。 [0011] (3) the use of a heat throttle effect at normal temperature gas directly in the heat generating freezer, using helium as cryosurgery rewarming (40K helium inversion temperature, throttle expansion exotherm at room temperature) . 此种复温方式带来极快的复温和响应速度,可控性好,且结构简单,不需要额外装置。 Bring this rewarming rewarming fast response speed, good controllability, simple structure, no additional equipment. 但缺点是复温用的氦气属昂贵的稀有气体,依赖进口,价格约为同量同级氩气的8〜1〇倍,成本很高;同时氦气升温能力有限,最高只能达到320K左右。 But the drawback is rewarming genus expensive helium gas rare gas, imported, the price is about the same amount of the same level of argon 8~1〇 times, high cost; while limited heating capacity of helium, can only reach 320K about.

发明内容 SUMMARY

[0012] 本发明解决了气体节流型冷冻外科治疗设备现存的复温难题,纠正了节流致冷型气体只能用于致冷这一技术偏见,提出利用节流致冷型高压气体分流复温和排气复温、利用高压余气和普压气体复温、兼容节流致热型气体复温、并可主动加热的新型气体节流型冷冻外科系统的设计和实施方案,可经济和灵活地实现冷冻、复温和加热三种功能。 [0012] The present invention solves the throttling type cryosurgical gas treatment device rewarming existing problems, correct throttling refrigerant for a refrigerator of this type can only be gas technical prejudice, proposed the use of high-pressure refrigerant gas bypass throttle rewarming exhaust rewarming, and the high pressure residual gas pressure P gas rewarming compatible expansion type design and implementation of cryosurgical system pyrogenic throttling type gas rewarming, and new gas is actively heated, and can be economically flexible implementation of freezing, rewarming and heated three functions. 以下举例用氩氦刀,但本发明包括所有使用气体节流效应的低温冷冻外科设备,不限于氩氦刀。 The following Examples using cryoablation, the present invention includes all surgical equipment using cryogenic gas throttling effect is not limited to cryosurgery.

[0013] 为了解决上述复温技术问题,本发明提出的一种气体节流型冷冻外科装置,其基本结构包括高压冷冻气路、低压供气气路、低压致热气路、分流气路、冷冻器输气管和冷冻器;所述高压冷冻气路包括与高压气源出气口依次相连的高压气体输入管、冷冻气体总管和冷冻器输气管,所述高压气体输入管上设有高压气压表和高压调压阀,所述高压气体输入管与所述冷冻气体总管的连接处设有高压限压阀,所述高压气体输入管上、位于所述高压调压阀与所述高压限压阀之间的管段上设有第一三通;所述低压供气气路包括:与高压余气气源相连的余气输出口、与普压气源相连的普压输出口、与氦气源相连的氦气输出口; 所述高压余气气源与所述余气输出口的连接处设有余气气压表和余气调压阀;所述普压气源与普压输出口的连接处设有普压气压表和普压调压 [0013] In order to solve the above technical problem rewarming A gas throttling type cryosurgical apparatus proposed by the present invention, the basic structure comprising high pressure freezing air passage, the low pressure gas supply passage, a low pressure induced hot gas path, the gas bypass passage, frozen pipeline and freezer unit; the high-pressure refrigerating circuit comprises a high pressure gas inlet pipe and the outlet pressure air source connected in sequence, and the freezer freezing gas pipeline manifold, said high pressure gas supply line and is provided with a high-pressure gauge high-pressure regulating valve, the high pressure gas inlet pipe connected to the refrigerant gas at the high pressure manifold is provided with a pressure limiting valve, said high pressure gas inlet tube, high-pressure regulating valve located in the pressure-limiting valve and the high pressure of a first pipe section is provided between the three-way; said low voltage supply circuit comprises: a high-pressure residual gas output port connected to a source of gas than air, pressure output port P is connected to the pressure air source P, is connected to the helium gas source helium output port; connecting the high-pressure residual gas at the gas source and the gas outlet is provided than the residual air and residual gas gauge pressure regulating valve; connector disposed at said air pressure source P and the output port of the pressure P there pressure gauge P and the pressure regulator P ;所述氦气源与所述氦气输出口的连接处设有氦气气压表和氦气调压阀;所述低压致热气路包括低压汇流气管和致热气体总管,所述低压汇流气管的一端为低压气体输入口,所述余气输出口、所述普压输出口和所述氦气输出口之一接至所述低压气体输入口;所述低压汇流气管的另一端连接至一致热气体总管;所述低压汇流气管上设有低压电磁阀和低压限压阀,所述低压汇流气管上、^于所述低压电磁阀和低压限压阀之间的管段上设有第二三通;所述第一三通与所述第二三通之间连接有分流气管,所述分流气管上设有分流电磁阀,所述分流气管和所述分流电磁阀构成了所述分流气路;所述冷冻器输气管连接在所述冷冻气体总管和所述致热气体总管的末端之间,并通过第四三通连接至冷冻器的进气管,所述冷冻器输气管上位于所述冷f气彳f总管的末端与所述第 ; Barometers the helium gas source is provided with helium and helium pressure regulating valve is connected with the output port of said helium; the low-pressure actuator comprises a hot gas path and the low-voltage bus pyrogenic gas manifold pipe, the low-voltage bus duct one end of a low pressure gas inlet, the residual gas outlet, the pressure P output port and one output port of the helium gas to said low pressure inlet; the other end of the pipe is connected to the low-voltage bus agreement the hot gas manifold; low pressure solenoid valve provided with a pressure limiting valve and the low pressure on the low-voltage bus duct, on the low-voltage bus duct, ^ provided on the second three-pipe section between the low pressure and low pressure solenoid valve pressure limiting valve through; three-way connection between the first and the second three-way shunt tube, the split tube is provided with a solenoid valve diverter, said diverter duct and the bypass solenoid valve constituting said shunt gas passage ; the freezer pipeline connected between the end of the freezing gas manifold and the actuator of the hot gas manifold, and connected to the intake pipe through the fourth three-way freezer, the freezer is located on the pipeline with the first end of the left foot f cold gas manifold f 四三通之间的管路上设有冷冻器冷冻电磁阀,所述冷冻器输气管上位于所述致热气体总管的末端与所述第四三通之间的管路上设有冷冻器加热电磁阀。 Line between the four-way solenoid valve is provided with a freezer refrigeration, the gas pipeline of the freezer is located on the line between the actuator end of the hot gas manifold is provided with the fourth three-way electromagnetic heating freezer valve.

[0014] 本发明提出的另一种技术方案是,该气体节流型冷冻外科装置与上述基本结构不同仅在于:其中,独立的设有一条氦气输入管,自氦气源经过氦气输出口连接至该氮气输入管,所述氦气输入管上设有所述氦气气压表、所述氦气调压阀、氦气电磁阀和氦气限压阀, 所述氦气输入管在第三三通处接入致热气体总管。 [0014] Another solution proposed by the present invention, the gas throttling type cryosurgical apparatus differs only in that the above-described basic structure: which is provided with an independent helium supply line, a helium from helium source through output nitrogen inlet port is connected to the tube, with the helium gas pressure gauge, said pressure regulating valve helium, helium and the helium pressure limiting solenoid valve on the inlet tube helium, the helium gas in the inlet pipe the third three-way access pyrogenic gas manifold.

[0015] 进一步讲,所述致热气体总管上设有气体加热器。 [0015] Further, the actuator is provided on the hot gas heater gas manifold.

[0016] 所述高压冷冻气路的所述冷冻气体总管的末端和所述低压加热气路中的所述致热气体总管的末端通过多个串联的第四三通并联有多条冷冻器输气管,每条冷冻器输气管的末端均与一冷冻器相连。 [0016] The gas manifold end pyrogenic the end of the high-pressure refrigerant gas manifold frozen gas passage and the low pressure heating gas passage by a plurality of parallel fourth three-way series of a plurality of input freezer pipe, each end of each freezer pipeline connected to a freezer. 实现多冷冻器同步冷冻或复温操作。 Synchronous multi freezer thawing or freezing operation.

[0017] 与冷冻器输气管连接的所述冷冻器冷冻电磁阀、冷冻器加热电磁阀、第四三通、冷冻器进气管和冷冻器构成了一连接在所述冷冻气体总管末端与所述致热气体总管末端之间的组件A;其特征在于,在所述冷冻气体总管末端与所述致热气体总管末端之间并联有多个组件A,实现多冷冻器独立冷冻或复温操作。 [0017] The freezer refrigeration freezer solenoid valve connected pipeline, freezer heating solenoid valve, a fourth three-way, freezer and freezer intake pipe connected to constitute a refrigerant gas at the end of the manifold a actuator assembly between the end of the hot gas manifold; wherein, between the end of the freezing gas and the hot gas manifold end of the manifold with a plurality of parallel actuator assemblies a, independent multi-freezer thawing or freezing operation.

[0018] 所述冷冻器为利用气体的焦耳-汤姆逊节流效应产生低温的气体节流致冷型冷冻器;所述高压气源是节流膨胀致冷型气体中的一种或几种之混合物;所述高压气源、所述高压余气气源、所述普压气源和所述氦气源来自于气瓶、气罐、气栗、杜瓦罐和压缩机中的任何一处。 [0018] The freezer joules using a gas - generating a low temperature Thomson gas throttling effect of the throttle refrigerator freezer type; the source of high pressure gas refrigerant is throttled and expanded type of one or more gas the mixture; the high pressure air source, said high pressure gas source residual gas, the pressure gas source and said P source is from a helium cylinder, tank, gas Li, Dewar tanks and a compressor of any place.

[0019] 利用上述本发明气体节流型冷冻外科装置,可以实现以下几种复温方式: [0019] With the present invention, the gas throttling type cryosurgical apparatus can be realized following rewarming:

[0020] 一、分流复温方式: [0020] First, the shunt rewarming:

[0021] 开启高压调压阀、分流电磁阀和冷冻器加热电磁阀,同时关闭低压电磁阀和冷冻器冷冻电磁阀;复温气体由所述高压气体输入管上所述第一三通引出,经所述分流气管和所述分流电磁阀,通过所述第二三通,接入所述低压汇流气管,经所述低压限压阀限压,接入所述致热气体总管,由所述冷冻器加热电磁阀控制,经所述冷冻器输气管和所述第四三通输出至所述冷冻器,通过热交换实现复温操作,当冷冻器温度达到(TC至正常体温时或所述高压气压表显示气压降至1个大气压时,结束该分流复温; [0021] Open high pressure regulator valve, a solenoid valve and diverter freezer heating solenoid valve, while closing solenoid valve and a low pressure solenoid valve freezing freezer; rewarming by the gas on the high pressure gas pipe of the first three-input leads, via the shunt pipe and said diverter solenoid valve, the actuation of said second hot gas manifold by a three-way, low-voltage bus access to the trachea, via the low pressure limiting valve pressure limiting access by said heating solenoid valve control freezer, the freezer via pipelines and the fourth three-way output to the freezer, thawed achieved by heat exchange operation, when the freezer temperature reaches (TC to normal body temperature or when the high pressure gauge to 1 atm pressure display, the end of the shunt rewarming;

[0022] 二、余气复温方式: [0022] Second, the residual gas rewarming way:

[0023]将所述余气输出口接至所述低压气体输入口,开启余气调压阀、低压电磁阀和冷冻器加热电磁阀,同时关闭分流电磁阀和冷冻器冷冻电磁阀;复温气体自所述高压余气气源,经所述余气气压表和所述余气调压阀调控,由所述余气输出口接入所述低压气体输入口,再经所述低压电磁阀,接入所述低压汇流气管,经所述低压限压阀限压,接入所述致热气体总管,由所述冷冻器加热电磁阀控制,经所述冷冻器输气管和所述第四三通输出至所述冷冻器,通过热交换实现复温操作,当冷冻器温度达到0°C至正常体温时或所述余气气压表显示气压降至1个大气压时,结束该余气复温; [0023] The residual gas outlet to said low-pressure inlet gas, residual gas pressure regulating valve open, the low pressure solenoid valve and a freezer heating solenoid valve, while closing solenoid valve and the bypass solenoid valve freezing freezer; rewarming the high pressure residual gas from the gas source of gas, the residual gas through the residual gas pressure regulating valve and pressure gauge regulated by the residual gas outlet to access the low pressure gas inlet, and then through the low pressure solenoid valve , bus access to the low-pressure pipe, the low pressure limiting valve via a pressure limiting access the pyrogenic gas manifold, heated by the solenoid valve control freezer, the freezer through the fourth pipeline and when the three-way output to the freezer, thawed achieved by heat exchange operation, when the freezer temperature reaches 0 ° C to normal body temperature or the residual gas pressure gauge to 1 atm displayed, the end of the residual gas complex temperature;

[0024] 三、普压复温方式: [0024] Third, the pressure P rewarming:

[0025]将所述普压输出口接至所述低压气体输入口,开启普压调压阀、低压电磁阀和冷冻器加热电磁阀,同时关闭分流电磁阀和冷冻器冷冻电磁阀;普压气体自所述普压气源,经所述普压气压表和所述普压调压阀调控,由所述普压输出口接入所述低压气体输入口,再经所述低压电磁阀,接入所述低压汇流气管,经所述低压限压阀限压,接入所述致热气体总管,由所述冷冻器加热电磁阀控制,经所述冷冻器输气管和所述第四三通输出至所述冷冻器,通过热交换实现复温操作,当冷冻器温度达到or至正常体温时或所述普压气压表显示气压降至1个大气压时,结束该普压复温; [0025] P the pressure output port to said low pressure gas inlet, a pressure regulating valve opening pressure P, a low pressure solenoid valve and the solenoid valve freezer heating, while closing solenoid valve and the bypass solenoid valve freezing freezer; pressure P Poor gas from the pressure gas source, through the pressure gauge P and the pressure regulating valve regulation P, an output port of said access by said low-pressure inlet gas pressure P, and then through the low pressure solenoid valve, bus access to the low-pressure pipe, the low pressure limiting valve via a pressure limiting access the pyrogenic gas manifold, heated by the solenoid valve control freezer, the freezer via pipelines and the fourth three- when the gate output to the freezer, thawed achieved by heat exchange operation, when the freezer temperature reaches to a normal body temperature or pressure gauge P or the display of the pressure to 1 atm, the end of the pressure P rewarming;

[0026] 四、节流复温方式,有以下两种情形之_ [0026] Fourth, the throttle rewarming, there are the following two scenarios _

[0027] 一是,氦气直接输入所述低压气体输入口并由低压限压阀限压的情形,开启氦气调压阀、低压电磁阀和冷冻器加热电磁阀,同时关闭分流电磁阀和冷冻器冷冻电磁阀;氦气由所述氦气源,经所述氦气气压表和所述氦气调压阀,由所述氦气输出口接入所述低压气体输入口,再经所述低压电磁阀,接入所述低压汇流气管,经所述低压限压阀限压,接入所述致热气体总管,由所述冷冻器加热电磁阀控制,经所述冷冻器输气管和所述第四三通输出至所述冷冻器,通过节流放热(当通过所述低压限压阀后氦气压力大于氦气节流工作压力时)或热交换(当通过所述低压限压阀后氦气压力小于氦气节流工作压力时)实现复温操作,当冷冻器温度达到(TC至正常体温时或所述氦气气压表显示气压降至1个大气压时,结束该节流复温; [0027] First, a low-pressure helium gas directly into the inlet of the case a low pressure by the pressure-limiting pressure limiting valve, open the helium pressure regulating valve, a low pressure solenoid valve and the solenoid valve freezer heating, while closing solenoid valve and diverter frozen freezer solenoid valve; the helium gas from the helium gas source, through the helium and the helium pressure gauge pressure regulating valve, the helium gas from the outlet of the low pressure gas inlet port access, and then by the said low pressure solenoid valve, the low-voltage bus access to the trachea, via the low pressure limiting valve limiting pressure, gas access to the pyrogenic manifold solenoid valve is controlled by heating the freezer, the freezer via pipelines and (when the pressure limiting valve by the low-pressure helium gas pressure is greater than the throttle operating pressure helium) to the output of the fourth three-way freezer, heat or heat exchange through the throttle (when the low pressure through a pressure limiting valve when the helium pressure is less than the working pressure of the helium gas throttle) to achieve rewarming operation, when the freezer temperature reaches (TC body temperature to a normal display or the helium gas pressure gauge to 1 atm, the end of the throttle rewarming ;

[0028] 二是,氦气经由独立的氮气通路接入所述致热气体总管并将所述氦气限压阀设定为氦气节流工作压力的情形,开启氦气调压阀、氦气电磁阀和冷冻器加热电磁阀,同时关闭所述低压电磁阀、分流电磁阀和冷冻器冷冻电磁阀;氦气由所述氦气源,经所述氦气输入管上的所述氦气气压表、所述氦气调压阀、所述氦气电磁阀和所述氦气限压阀,于所述第三三通处,接入所述致热气体总管;经所述冷冻器输气管和所述冷冻器加热电磁阀控制,由所述第四三通处,再输出至所述冷冻器,通过节流放热(当通过所述低压限压阀后氦气压力大于氦气节流工作压力时)或热交换(当通过所述低压限压阀后氦气压力小于氦气节流工作压力时)实现复温操作,当冷冻器温度达到0°C至正常体温时或所述氦气气压表显示气压降至1个大气压时,结束该节流复温; [0028] Second, helium, nitrogen via a separate access path and the actuation of the hot helium gas manifold pressure limiting valve is set to the working pressure of the helium gas throttling case, the pressure regulating valve open helium, helium a solenoid valve and a freezer heating solenoid valve, while closing the low-pressure electromagnetic valve, a solenoid valve and bypass solenoid valve freezer refrigeration; the helium gas from the helium gas source, through the inlet tube of the helium gas pressure of helium table, the helium pressure regulating valve, said solenoid valve and said helium helium pressure limiting valve, to the third three-way, the access of the hot gas manifold actuator; freezer via the pipeline and the heating solenoid valve control freezer, the tee by the fourth, and then output to the freezer, heat through the throttle (when the pressure limiting valve by the low-pressure helium gas pressure is greater than the working pressure helium gas orifice ) or at the heat exchanger (when the pressure limiting valve by the low-pressure helium gas helium pressure is less than the throttle operating pressure) to achieve rewarming operation, when the freezer temperature reaches 0 ° C to normal body temperature or the helium barometer displaying the pressure to 1 atm, the end of the throttle rewarming;

[0029] 五、排气复温方式,包括以下两种情形之一: [0029] V. exhaust rewarming, comprises one of the following two situations:

[0030] 一是,在节流冷冻操作后,关闭所述高压调压阀并同时开启冷冻电磁阀,所述高压冷冻气路中积存的冷冻气体将持续通入冷冻器,直至冷冻器温度达到0°c至正常体温时或所述高压气压表显示气压降至1个大气压时,结束排气复温; [0030] First, the freezing operation throttled, the pressure regulating valve to close and open simultaneously the high pressure refrigeration valve, the high-pressure refrigerating gas passage of refrigerating gas will continue into a freezer, a freezer until the temperature reached when 0 ° c to normothermic or when the high pressure gauge to 1 atm pressure display, end of the exhaust rewarming;

[0031] 二是,复温操作后关闭所述余气调压阀、所述普压调压阀和所述氦气调压阀,开启所述低压电磁阀或所述低压电磁阀和氦气电磁阀,所述冷冻器加热电磁阀,所述低压管路中剩余致热气体将持续通入所述冷冻器,直至冷冻器温度达到〇°c至正常体温时或所有气压表显示气压降至1个大气压时,结束排气复温, [0031] Second, the residual gas pressure control valve to close after rewarming operation, the pressure P and the pressure regulating valve helium pressure regulating valve, opening the low pressure solenoid valve or the solenoid valve and low pressure helium solenoid valve, a freezer heating solenoid valve, the low-pressure line pyrogenic remaining gas will continue into the freezer, a freezer until the temperature reaches square ° c to normal body temperature or when all of the pressure gauge display reduced an atmospheric pressure, the exhaust end of rewarming,

[0032] 与现有技术相比,本发明的有益效果是: [0032] Compared with the prior art, the beneficial effects of the present invention are:

[0033] (1)分流复温:本发明纠正了节流致冷型高压气体仅用于冷冻的技术偏见,通过分流和限压,使其直接用于复温。 [0033] (1) shunt rewarming: The present invention corrects the high-pressure refrigerant gas is throttled only technical prejudice frozen through the shunt and voltage limiting, it was used directly in rewarming. 我们的研究表明当通入冷冻器的氩气压力低于其20MPa的节流工作压力时,节流降温效果迅速减弱和消失;此时冷冻器内的常温氩气(300K)将与其外部冷冻的组织(100-273K)热交换而实现复温。 Our research suggests that when the freezer into argon pressure lower than the operating pressure of its throttle when 20MPa, the cooling effect throttling and decreased rapidly disappear; in this case argon at room temperature (300K) in the freezer to freeze the outside thereof organization (100-273K) heat exchange is achieved rewarming.

[0034] ⑵排气复温:本发明利用排空设备余气的过程用于冷冻器复温。 [0034] ⑵ exhaust rewarming: the process of the present invention using a residual gas evacuation device for a freezer thawing. 冷冻外科设备使用后需排空设备余气,因此时所有气源已关闭且经限压阀的作用,设备内气体压力将降至致冷工作压力下,排气过程将具有复温作用。 After using the device for an emptying device cryosurgical residual gas, so all the gas source is closed and through the action of the pressure limiting valve, the gas pressure within the apparatus will be reduced to a pressure at a cooling operation, the exhaust gas having rewarming process effect. 此时冷冻器排出的致冷的氩气将和致热的氩气/氦气一起为冷冻器复温,既实现排空余气,也实现复温,一举两得,进一步降低对气体的要求和使用成本。 At this point chiller refrigeration argon discharged from the pyrogenic and argon / helium together freezer thawing, realized spare exhaust gas, but also to achieve rewarming, serve two purposes, to further reduce the requirements for the use of gas and cost.

[0035] (3)余气复温:本发明充分利用了低于冷冻工作压力、不能用于冷冻的剩余高压致冷气体用于复温。 [0035] (3) residual gas rewarming: full advantage of the present invention the operating pressure is below the freezing, freezing can not be used for the remaining high-pressure refrigerant gas for rewarming. 氩氦刀使用过程中低于21MPa的氩气不能使用,只能全瓶退回气体生产商放掉余气以重新灌装才能保持99.999 %的高纯要求。 Cryocare the course of less than 21MPa argon gas can not be used, only returned to full gas bottle manufacturer let go of the residual gas to be refilled in order to maintain 99.999% high purity requirements. 本发明利用此种余气复温,达到与昂贵的氦气复温相近的效果。 The present invention utilizes such rewarming residual gas, to achieve the effect similar to the expensive helium rewarming.

[0036] (4)普压复温:本发明也可利用常见普压灌装(12〜15MPa)的任意气体用于复温。 [0036] (4) Poor Pressure rewarming: The present invention may also utilize common filling pressure P (12~15MPa) for any gas rewarming. 该种普压气体随处可见并使用普压钢瓶(成本为高压钢瓶的八分之一),其气体价格约为同体积高压气体的十分之一。 The kind of the gas pressure P and used everywhere cylinder pressure P (cost of high-pressure cylinders, one eighth), with about one-tenth of the volume of high-pressure gas the gas price.

[0037] (5)节流复温:本发明也兼容节流致热复温气体(如氦气)复温并整合到低压复温管路中,以发挥氦气快速复温的效能。 [0037] (5) a throttle rewarming: a throttle actuator of the present invention is also compatible with rewarming hot gases (such as helium) rewarming and integrated into a low pressure line rewarming, helium rapid rewarming to exert efficacy. 同时我们的研宄发现,由于氦气反转温度接近绝对零度,且其节流致热能力(焦耳-汤姆逊系数)在150K〜400K间不随温度变化而改变,引入气体加热器加热氦气将叠加节流复温和传导致热双重效果,大大增强装置的复温效果和速度。 We study based on the discovery, since helium temperature close to absolute zero inverted, and throttling capabilities pyrogenic (Joule - Thomson coefficient) does not change with temperature change between 150K~400K, introducing the helium gas heater rewarming superimposed throttling heat transfer results in a double effect, greatly enhancing the effects of rewarming and speed of the device. [0038] 气体预热:本发明也引入气体加热装置预热复温气体,使其用于可控加热病变组织,实现了肿瘤热疗效果。 [0038] Gas preheating: The present invention is also introduced into the gas preheating rewarming gas heating means, so as to controllably heat the diseased tissue, tumor hyperthermia results achieved.

[0039]综上,本发明所用气体成本低:利用高压氩气的分流、余气和普压气体作为复温气体,其成本将大大低于稀有的节流致热型高纯氦气(相差8倍以上);通过利用设备排气复温及使用不能用于冷冻的高压气源余气复温,可以提高气体利用率,避免浪费,节能环保。 [0039] In summary, the low cost of the gas used in the present invention: the use of the shunt high pressure argon, residual gas pressure P gas and As gas is thawed, the cost will be much lower than the thermal type Helium rare throttle actuator (difference 8 times); high pressure air source by more than the exhaust gas rewarming and rewarming device is not used for freezing, can increase the gas utilization efficiency and avoid waste, energy saving. 本发明即可利用现有氦气复温技术,也可利用高压余气及随处可见的普压气体复温,不需要单独气体收集、压缩和推动装置,降低了装备和使用门槛,促进冷冻消融技术的普及。 The present invention can utilize existing technology rewarming helium, may also be utilized and the high pressure residual gas pressure P gas everywhere rewarming, no separate gas collection, compression and pushing means, and reducing the threshold for using the equipment, facilitate cryoablation the popularity of technology. 通过引入气体加热器,可直接预热低压气体至肿瘤热疗温度并输入冷冻器,突破了现有设备的升温限值,提高升温性能和增加了热疗的功能。 By introducing a gas heater, a low pressure gas is preheated directly to the tumor and hyperthermia temperature input freezer, warmed to break the limit of existing equipment, improve the temperature rise performance and increased functionality hyperthermia.

附图说明 BRIEF DESCRIPTION

[0040]图1为本发明气体节流型冷冻外科装置实施例1的示意图; Example 1 a schematic view of a gas throttling device type cryosurgical embodiment [0040] Figure 1 of the present invention;

[0041]图2为本发明气体节流型冷冻外科装置实施例2的示意图; [0041] FIG gas throttling type cryosurgical apparatus 2 is a schematic diagram of the embodiment of the present invention;

[0042]图3为本发明气体节流型冷冻外科装置实施例3的示意图; 3 is a schematic diagram of a gas throttling device type cryosurgical embodiment [0042] FIG. 3 of the present invention;

[0043]图4为本发明气体节流型冷冻外科装置实施例4的示意图; [0043] FIG. 4 type cryosurgical gas throttle device 4 is a schematic diagram of the embodiment of the present invention;

[0044]图5为本发明气体节流型冷冻外科装置实施例5的示意图; 5 is a schematic diagram of a gas throttling device type cryosurgical embodiment [0044] FIG. 5 of the present invention;

[0045]图6为本发明气体节流型冷冻外科装置实施例6的示意图; [0045] FIG 6 gas throttling type cryosurgical apparatus of Example 6 is a schematic embodiment of the present invention;

[0046]图7为本发明中所用的冷冻器结构示意图; [0046] FIG. 7 of the present invention is used in a freezer structural diagram;

[0047]图8为实施例1排气复温模式的试验结果; [0047] FIG. 8 is a result of a test pattern according to the exhaust gas rewarming embodiment;

[0048]图9为实施例1余气复温模式的试验结果。 [0048] Example 9 is more than 1 air rewarming mode embodiment of the test results.

[0049]图中: [0049] FIG:

[0050] la—高压气源lb-高压气压表lc-高压调压阀 [0050] la- barometer pressure air source lb- high pressure high pressure regulator valve lc-

[0051] 2-高压气体输入管3-第一三通4-第二三通 First three-3- [0051] 2- high pressure gas inlet tube second three-4-

[0052] 5—高压限压阀6-冷冻气体总管7-冷冻器冷冻电磁阀 [0052] 5- 6- high-pressure refrigerant gas pressure limiting valve manifold solenoid valve freeze freezer 7-

[0053] 8—冷冻器输气管9-冷冻器9a-冷冻器进气管 [0053] 8- 9- pipeline freezer freezer freezer intake pipe 9a-

[0054] 9b-换热翅片9c-JT 口9d_膨胀腔 [0054] 9b- heating fins 9c-JT expansion chamber opening 9d_

[0055] 9e-冷冻器外壁9f-回流腔9h_冷冻器出气管 [0055] 9e- outer wall of the freezer chamber 9h_ 9f- reflux freezer outlet pipe

[0056]的―测温电偶10a-高压余气气源10b-余气气压表L〇〇57] 10c-余气调压阀10d-余气输出口11a-普压气源 [0056] - the galvanic 10a- temperature than the high-pressure gas sources in gas gauge L〇〇57 10b- I] I I 10d- 10c- gas regulating valve outlet gas pressure P gas source 11a-

[0058] lib-普压气压表11c-普压调压阀lid-普压输出口 [0058] lib- 11c- gauge pressure P P P pressure regulator valve pressure output port lid-

[0059] 12a-氦气源12b-氦气气压表12c-氦气调压阀 [0059] 12a- 12b- helium supply pressure regulating valve Helium Helium barometer 12c-

[0060] Ud-氦气输出口13_分流气管14-分流电磁阀 [0060] Ud- helium gas outlet pipe 13_ split diverter solenoid valve 14-

[0061] 15-氦气输入管16-氦气电磁阀17-氦气限压阀 [0061] 15 helium helium supply line solenoid valve 17- 16- helium pressure limiting valve

[0062] 1S-低压气体输入口19-低压电磁阀20-低压汇流气管 [0062] 1S- low pressure low pressure gas inlet solenoid valve 20 19- voltage bus duct

[0063] 21-低压限压阀22-第三三通23-气体加热器 [0063] The low-pressure limiting valve 21 22- 23- third three gas heater

[0064] 24-致热气体总管25-冷冻器加热电磁阀26-第四三通 [0064] 24- pyrogenic gas manifold 25 is heated freezer fourth three-way solenoid valve (26)

具体实施方式 Detailed ways

[0065]下面结合附图和具体实施例对本发明技术方案作进一步详细描述,所描述的具体实施方案仅对本发明进行解释说明,并不用以限制本发明。 [0065] The following drawings and specific embodiments of the aspect of the invention will be further described in detail, specific embodiments of the present invention will be described only for explanation, not intended to limit the present invention in combination. 所有实施例使用的冷冻器为美国HealthTronics公司制造的冷冻器1 • 7mm、® 2 • 4mm、® 3.8mm等)。 All embodiments of freezer used was manufactured by US HealthTronics freezer 1 • 7mm, ® 2 • 4mm, ® 3.8mm, etc.).

[0066]实施例1:如图1所不,本发明一种气体节流型冷冻外科装置,包括高压冷冻气路、 低压供气气路、低压致热气路、分流气路、冷冻器输气管8和冷冻器9。 [0066] Example 1: FIG. 1 is not a present invention, the gas throttling type cryosurgical apparatus comprises a high pressure refrigeration gas passage, a low pressure gas supply passage, a low pressure induced hot gas path, the gas bypass passage, freezer pipeline 8 and 9 freezer.

[0067]所述高压冷冻气路包括与高压气源la出气口依次相连的高压气体输入管2和冷冻气体总管6,所述高压气体输入管2上设有高压气压表lb和高压调压阀lc,所述高压气体输入管2与所述冷冻气体总管6的连接处设有高压限压阀5;所述高压气体输入管2上、位于所述高压调压阀lc与所述高压限压阀5之间的管段上设有第一三通3。 [0067] The refrigerating circuit comprises a high-pressure high-pressure gas and pressure air source la is connected to the outlet successively freezing gas supply line 2 and the manifold 6, a high pressure gauge and the high pressure regulator valve lb 2 on the high pressure gas inlet pipe lc, the high pressure gas supply line 2 is connected to the refrigerant gas manifold 6 is provided at the high pressure limiting valve 5; on the high pressure gas supply line 2, the high-pressure regulating valve located in the high-pressure-limiting and lc It is provided between the upper pipe section 5 of the first three-way valve 3.

[0068] 所述低压供气气路包括:与高压余气气源10a相连的余气输出口10d、与普压气源1 la相连的普压输出口1 Id、与氦气源12a相连的氦气输出口12d;所述高压余气气源10a与所述余气输出口的连接处设有余气气压表10b和余气调压阀10c;所述普压气源11a与普压输出口1 Id的连接处设有普压气压表1 lb和普压调压阀1 lc;所述氦气源12a与所述氦气输出口12d的连接处设有氦气气压表12b和氦气调压阀12c。 [0068] The low-pressure gas supply manifold comprising: a residual gas outlet connected to the source of high pressure air over the air 10a 10d, the pressure P and the output port connected to a source of air pressure P 1 la 1 Id, 12a is connected to a source of helium helium output port 12 d; the high-pressure gas source 10a and the residual gas is connected to the residual gas at the outlet of the residual air pressure gauge is provided, and the residual gas pressure regulating valve 10b 1OC; Pu said pressure gas source 11a and the output port pressure P 1 Id is provided at the junction P 1 lb pressure gauge P and the pressure regulating valve 1 lc; the helium gas to the helium source 12a and the output port 12d is provided at the connection 12b and helium transfer helium barometer pressure valve 12c.

[0069] 所述高压气源1是节流膨胀致冷型气体中的一种或几种之混合物;所述高压气源la、所述高压余气气源l〇a、所述普压气源11a和所述氦气源12a来自于气瓶、气罐、气泵、杜瓦罐和压缩机中的任何一处。 [0069] The high pressure air source 1 is throttled and expanded refrigerant mixture of one or more type of gas; La of the pressure air source, said high pressure gas source l〇a residual gas, the gas pressure P the helium supply source 11a and 12a from any one cylinder, tank, pump, and compressor Dewar tank.

[0070] 所述低压致热气路包括低压汇流气管20和致热气体总管24,所述低压汇流气管20 的一端为低压气体输入口18,所述余气输出口l〇d、所述普压输出口lid和所述氦气输出口12d与所述低压气体输入口18之间为可拆卸连接;所述低压汇流气管2〇的另一端连接至所述致热气体总管24;所述低压汇流气管20上设有低压电磁阀19和低压限压阀21,所述低压汇流气管20上、位于所述低压电磁阀19和所述低压限压阀21之间的管段上设有第二三通4。 [0070] The low-pressure actuator circuit comprises a low-pressure hot gas pipe 20 and the bus pyrogenic gas manifold 24, one end of the low-voltage bus is a low-pressure pipe 20 of the gas inlet 18, the residual gas outlet l〇d, the pressure P helium and the lid outlet port 12d and the output of the low pressure gas inlet 18 as a detachable connection between; the other end of the low-voltage bus duct is connected to the actuator 2〇 hot gas manifold 24; the low-voltage bus Where a low pressure solenoid valve 19 and low pressure limiting valve 21 on the pipe 20, the low-voltage bus duct 20, located in the low pressure solenoid valve 19 and the second three-way is provided between the upper pipe section 21 low-pressure pressure limiting valve 4.

[0071] 所述第一三通3与所述第二三通4之间连接有分流气管I3,所述分流气管13上设有分流电磁阀14,所述分流气管13和所述分流电磁阀14构成了所述分流气路; [0071] The first and the second 3-way tee connection between the shunt pipe 4 I3, the shunt tube 13 and the bypass solenoid valve 14 is provided on the pipe diverter solenoid valve 13, the shunt 14 constitute the bypass air passage;

[0072] 所述冷冻器输气管8连接在所述冷冻气体总管6和所述致热气体总管24的末端之间,并通过第四三通26连接至冷冻器9的进气管9a,所述冷冻器输气管8上位于所述冷冻气体总管6的末端与所述第四三通26之间的管路上设有冷冻器冷冻电磁阀7,所述冷冻器输气管8上位于所述致热气体总管科的末端与所述第四三通26之间的管路上设有冷冻器加热电磁阀25。 [0072] The freezer pipeline end 8 is connected between the manifold 6 and the refrigerant gas induced hot gas manifold 24, and connected to the intake pipe 9 of the freezer 9a through the fourth three-way 26, the freezer pipeline end 8 located at the manifold 6 and the refrigerant gas pipe line 26 between the fourth three-way solenoid valve is provided with a freezer refrigeration 7, the pipeline located in the freezer pyrogenic 8 Section gas manifold end path between the tube 26 is provided with the fourth three-way solenoid valve 25 is heated freezer.

[0073]本发明中的所述冷冻器9为利用气体的焦耳-汤姆逊节流效应产生低温的气体节流致冷型冷冻器。 [0073] In the present invention the freezer gas using Joule 9 - Thomson throttling effect produced gas expansion cryogenic freezer type refrigerator. 其一种典型的结构如图7所示,所述冷冻器9包括冷冻器进气管9a、换热翅片%、JT口9c、膨胀腔9d、冷冻器外壁9e、回流腔9f和冷冻器出气管9h,所述膨胀腔M的尖端设有测温电偶9i,所述冷冻器的温度由所述测温电偶9i实时测量。 A typical configuration thereof shown in Figure 7, the freezer comprises a freezer intake pipe 9 9a, heating fin%, JT port 9c, the expansion chamber 9D, 9E outer wall of the freezer, the freezer and the flashback chamber 9f out trachea 9h, the expansion chamber is provided with a tip temperature M galvanic 9i, the freezer temperature measured by the temperature measuring galvanic 9i real time.

[0074]当然,本发明中所述冷冻器9应用部分的几何形状和具体细节结构不受限制,其应用部分的几何形状可以是饼形、球形、椭球形、球囊形、针状、柱状、杆状和管状中的任何一种;其细部结构的不同可以是冷冻探针、冷冻探杆、冷冻探头、冷刀、冷冻球囊、冷冻电极、超冷手术器、(^丫0口1"€^6、(^7〇1:1口和(^7〇1166(116中的一种。 [0074] Of course, the present invention is the geometry of the freezer applications 9 portion structure is not limited to the specific details, the geometry of the application portion may be pie-shaped, spherical, ellipsoid, balloon-shaped, acicular, columnar , and any one of the tubular rod; however, its detailed structure can be different cryoprobe, freezing probe, cryoprobe, cold knife, balloon frozen, freeze-electrode ultracold surgical device, (Ah 0 ^ 1 "€ ^ 6, (^ 7〇1: one kind (one 116 and (^ 7〇1166.

[0075] 实施例1实现的控制方法如下: [0075] The control method as implemented in Example 1:

[0076] 冷冻模式:节流冷冻型高压气体由高压气源la输出,由高压气压表lb和高压调压阀lc调控,经高压气体输入管2,接入高压限压阀5,经限压至冷冻工作压力后,接入冷冻气体总管6。 [0076] freezing mode: high-pressure gas expansion refrigeration by the high pressure gas source outputs la, lb and high pressure by the high pressure regulating valve lc barometer regulation, by high pressure gas inlet pipe 2, a high-pressure pressure limiting access valve 5, the pressure limiting after freezing to the working pressure, the access freezing gas manifold 6. 当启动冷冻器冷冻电磁阀7,高压冷冻气体由冷冻器输气管8经第四三通26通入冷冻器进气管9a;输入的冷冻气体在冷冻器进气管9a末端JT 口9c处节流膨胀至膨胀腔9d,通过相邻的冷冻器外壁9e与周围组织热交换、吸热制冷;回流腔9f回流的低温气体经换热翅片9b与冷冻器进气管9a进气发生热交换,冷却进气以提高节流效应后,经冷冻器出气管9h 流出并释放至空气中。 When the solenoid valve starts freezing freezer 7, the high pressure refrigerant gas pipeline 8 from the fourth three-way freezer 26 into the intake pipe 9a through a freezer; 9a 9c mouth end JT throttling refrigerant gas entered the intake pipe expansion in a freezer 9D to the expansion chamber, through an adjacent outer wall 9e freezing heat exchange with the surrounding tissue, the refrigerant absorbs heat; 9F reflux temperature gas through the flashback chamber and the freezing heat exchanger fins 9b 9a intake pipe of the intake heat exchange, to cool the intake after the throttling effect to increase gas via a pipe 9h flows freezer and released into the air. 冷冻器的温度由置于冷冻器前端内壁的测温电偶9i实时测量。 Measured by the temperature of the freezer to the front inner wall of the freezer temperature galvanic 9i real time.

[0077]本发明实施例1实现的复温模式根据复温气体的来源可分为分流复温模式、余气复温模式、普压复温模式、节流复温模式和排气复温模式,其中,余气复温模式、普压复温模式和节流复温模式中,所述余气输出口、所述普压输出口和所述氦气输出口之一接至所述低压气体输入口。 [0077] Example 1 of the present invention is implemented according to the source mode rewarming rewarming gas may be divided into split rewarming mode, residual gas rewarming mode, rewarming pressure P mode, the exhaust mode and the throttle rewarming mode rewarming wherein the residual gas rewarming mode, P mode and the throttle pressure rewarming rewarming mode, the residual gas outlet, the pressure P output port and one output port of the helium gas to said low pressure input. 下面具体描述各复温模式: The following description of particular modes rewarming:

[0078] (1)分流复温模式:开启高压调压阀lc、分流电磁阀14和冷冻器加热电磁阀25,同时关闭低压电磁阀19和冷冻器冷冻电磁阀7;复温气体由高压气体输入管2上第一三通3引出,经分流气管13和分流电磁阀14,通过第二三通4,接入低压汇流气管20,经所述低压限压阀21限压,接入所述致热气体总管24,由所述冷冻器加热电磁阀25控制,经所述冷冻器输气管8和所述第四三通26输出至所述冷冻器9,通过热交换实现复温操作,当冷冻器温度达到〇°C至正常体温时或所述高压气压表lb显示气压降至1个大气压时,结束该分流复温。 [0078] (1) rewarming split modes: a high pressure regulator valve open LC, bypass solenoid valve 14 and solenoid valve 25 freezer heating, while closing the low pressure solenoid valve 19 and solenoid valve 7 freezing freezer; rewarming gas from the high pressure gas 2 a first input lead pipe tee 3, the bypass pipe 13 and the bypass solenoid valve 14, through the second 4-way, low-voltage bus access pipe 20, through the low pressure-limiting pressure limiting valve 21, access to the pyrogenic gas manifold 24, heated by the solenoid valve 25 controls the freezer, the freezer via pipeline 8 and the fourth three-way output 26 to the freezer 9, rewarming to achieve heat exchange operation, when when the freezer temperature reaches square ° C to normal body temperature or pressure of the high pressure gauge lb show a reduced atmosphere, the end of the shunt rewarming.

[0079] (2)余气复温模式:将所述余气输出口10d接至所述低压气体输入口18,开启余气调压阀10c、低压电磁阀19和冷冻器加热电磁阀25,同时关闭分流电磁阀14和冷冻器冷冻电磁阀7;复温气体自所述高压余气气源10a,经所述余气气压表l〇b和所述余气调压阀l〇c调控,由所述余气输出口l〇d接入所述低压气体输入口18,再经所述低压电磁阀19,接入所述低压汇流气管20,经所述低压限压阀21限压,接入所述致热气体总管24,由所述冷冻器加热电磁阀25控制,经所述冷冻器输气管8和所述第四三通26输出至所述冷冻器9,通过热交换实现复温操作,当冷冻器温度达到〇°C至正常体温时或所述余气气压表l〇b显示气压降至1 个大气压时,结束该余气复温。 [0079] (2) residual gas of rewarming mode: the residual gas output port 10d is connected to the low pressure gas inlet 18, gas pressure regulating valve 1OC I open, a low pressure solenoid valve 19 and solenoid valve 25 freezer heating, while closing the bypass solenoid valve 14 and the solenoid valve 7 freezing freezer; rewarming high pressure gas from the gas source than gas 10a, through the residual gas and the residual gas gauge l〇b l〇c regulated pressure regulating valve, the residual gas from the outlet of the low pressure l〇d access to gas inlet 18, and then through the low pressure solenoid valve 19, the low-voltage bus access pipe 20, through the low pressure-limiting pressure limiting valve 21, then rewarming pyrogenic into the gas manifold 24, heated by the solenoid valve 25 controls the freezer, the freezer via pipeline 8 and the fourth three-way output 26 to the chiller 9, the heat exchange is achieved by operation, when the freezer temperature reaches square ° C to normal body temperature than the air or gas pressure gauge l〇b displayed to 1 atm, the end of the residual gas rewarming.

[0080] (3)普压复温模式:将所述普压输出口lid接至所述低压气体输入口18,开启普压调压阀11 c、低压电磁阀19和冷冻器加热电磁阀25,同时关闭分流电磁阀14和冷冻器冷冻电磁阀7;复温气体自所述普压气源1 la,经所述普压气压表1 lb和所述普压调压阀1 lc调控,由所述普压输出口1 Id接入所述低压气体输入口I8,再经所述低压电磁阀19,接入所述低压汇流气管20,经所述低压限压阀21限压,接入所述致热气体总管24,由所述冷冻器加热电磁阀25控制,经所述冷冻器输气管8和所述第四三通26输出至所述冷冻器9,通过热交换实现复温操作,当冷冻器温度达到0°C至正常体温时或所述普压气压表11b显示气压降至1个大气压时,结束该普压复温。 [0080] (3) Pressure P rewarming mode: the lid pressure output port P connected to the low pressure gas inlet 18, the pressure regulating valve opening pressure P 11 c, a low pressure solenoid valve 19 and solenoid valve 25 freezer heating while closing the bypass solenoid valve 14 and the solenoid valve 7 freezing freezer; rewarming gas from the gas source pressure P 1 la, via the pressure gauge P 1 lb, and 1 lc of the P pressure adjustment valve regulated by the pressure P 1 Id access output port of said low pressure gas inlet I8, and then through the low pressure solenoid valve 19, the low-voltage bus access pipe 20, through the low pressure-limiting pressure limiting valve 21, the access pyrogenic said gas manifold 24, heated by the solenoid valve 25 controls the freezer, the freezer via pipeline 8 and the fourth three-way output of the freezer 26 to 9 to achieve rewarming operation by heat exchange, when the freezer temperature reaches 0 ° C to normal body temperature or pressure gauge 11b displays the pressure P when the pressure dropped to 1 atm, the end of the pressure P rewarming.

[0081] (4)节流复温模式:将所述氦气输出口12d接至所述低压气体输入口18,氦气由氦气源12a,经氦气气压表12b和氦气调压阀12c调控,由氦气输出口12d,接至低压气体输入口18,再经低压电磁阀19,汇入低压汇流气管20;当来自低压汇流气管20的氦气经低压限压阀21限压至氦气工作压力6.9MPa或以上,接入致热气体总管24,并经冷冻器加热电磁阀25控制,经冷冻器输气管8和所述第四三通26输出至冷冻器进气管9a,此节流复温气体在冷冻器进气管9a末端JT 口9c处节流膨胀至膨胀腔9d时放热致热,经相邻的冷冻器外壁9e为周围组织复温;当来自低压汇流气管20的氦气经低压限压阀21限压后压力低于氦气工作压力6.9MPa时,氦气将通过热交换实现复温操作,当冷冻器温度达到〇°C至正常体温时,结束该节流复温。 [0081] (4) throttling mode rewarming: the helium gas outlet port 12d is connected to the low pressure gas inlet 18, the helium gas consisting of helium source 12a, 12b by helium and helium pressure regulating valve barometer 12c regulated by the output port 12 d helium, connected to the low pressure gas inlet port 18, and then through the low pressure solenoid valve 19, low-voltage bus import pipe 20; when the helium gas through the low pressure pipe 20 from the low-voltage bus 21 of the pressure-limiting valve limiting pressure to helium working pressure 6.9MPa or more, the access pyrogenic gas manifold 24, and the solenoid valve 25 controls the heating by freezing, 8 outputs the freezer and the fourth three-way pipeline 26 to the intake pipe freezer 9a, this throttling rewarming freezer gas intake pipe end 9a JT throttling expansion to the mouth 9c and 9d pyrogenic heat expansion chamber, the outer wall adjacent to the freezer to the surrounding tissue rewarming 9e; when the bus from the low-pressure pipe 20 is after the low-pressure helium gas by pressure-limiting valve 21 the pressure-limiting pressure below the working pressure of 6.9 MPa helium, helium rewarming operation will be achieved by heat exchange, when the freezer temperature reaches square ° C to normal body temperature, the end of the throttle rewarming.

[0082] (5)排气复温模式,包括以下两种情形之一: [0082] (5) an exhaust rewarming mode comprises one of the following two situations:

[0083] 一是节流冷冻操作后高压排气复温,关闭所述高压调压阀lc并同时开启冷冻电磁阀7,所述高压冷冻气路中积存的冷冻气体将持续通入冷冻器9,由于此时通入冷冻器9的气体压力降至其冷冻工作压力下,其节流致冷效应将消失,该气体将变为复温气体。 [0083] First, the freezing operation after the high-pressure exhaust throttle rewarming, said high pressure regulator valve to close and open simultaneously frozen lc solenoid valve 7, the high-pressure refrigerating gas passage of refrigerating gas will continue to pass into the freezing 9 Since at this time the gas pressure into the freezer freeze-9 was reduced under the operating pressure, the refrigeration throttling effect will disappear, the gas becomes a gas rewarming. 此复温气体在冷冻器膨胀腔9d经相邻的冷冻器外壁9e与周围冷冻组织热交换而致热;回流的气体经回流腔9f和冷冻器出气管9h释放至空气中。 This rewarming freezer gas expansion chamber through 9d 9e adjacent to the outer wall of the freezer and the frozen tissue surrounding the hot heat exchanger caused; flashback chamber via a gas reflux 9f and 9h freezer outlet pipe is released into the air. 直至冷冻器温度达到〇°C至正常体温时或所述尚压气压表lb显不气压降至1个大气压时,结束排气复温; Freezer until the temperature reaches square ° C to normal body temperature or when the pressure is still not significant lb pressure gauge to 1 atm, the end of the exhaust rewarming;

[0084] 二是低压排气复温,复温操作后关闭所述余气调压阀l〇c、所述普压调压阀11c或所述氦气调压阀12c,开启所述低压电磁阀19和所述冷冻器致热电磁阀25,所述低压管路中剩余致热气体将持续通入所述冷冻器9为其复温,直至冷冻器温度达到〇°C至正常体温时或所有气压表显示气压降至1个大气压时,结束排气复温。 [0084] Second, the low pressure exhaust rewarming, the residual gas pressure control valve to close after rewarming l〇c operation, the pressure adjustment valve 11c or the P helium pressure regulating valve 12c, opening the electromagnetic low when the valve 19 and the freezer pyrogenic solenoid valve 25, the low-pressure line pyrogenic remaining gas will continue into the freezer for rewarming 9, until the freezer temperature reaches square ° C to normal body temperature or when all air pressure gauge display to 1 atm, the end of the exhaust rewarming.

[0085] 实施例2:如图2所示,在上述实施例1的基础上,所述致热气体总管24上位于所述低压限压阀21与冷冻器致热电磁阀25之间的管路上设有气体加热器23,使低压复温气体预热后再输入冷冻器,从而增强复温和加热的效果。 [0085] Example 2: 2, based on the first embodiment, the actuator 24 is positioned on the hot gas manifold the low pressure-limiting valve 21 and the freezer 25 between the thermal actuator solenoid way a gas heater 23, the low-pressure gas is preheated before thawing input freezer, thereby enhancing the effect of heating rewarming.

[0086]实施例2实现的控制方法包括冷冻模式和复温模式,根据复温气体的来源不同复温模式可分为⑴分流复温模式、(2)余气复温模式、(3)普压复温模式、⑷节流复温模式和(5)排气复温模式,其控制过程与实施例1中对应的方式基本相同,只是通过引入的气体加热器23,可直接预热低压气体并输入冷冻器,突破了现有设备的升温限值和升温速度,提高升温性能和增加了热疗的功能。 [0086] Example 2 control implemented method comprising freezing and thawing mode pattern, depending on the mode rewarming source gas may be divided into rewarming rewarming ⑴ split mode, (2) the residual gas rewarming mode, (3) P rewarming pressure mode, the throttle ⑷ rewarming mode and (5) an exhaust rewarming mode, which mode control procedure in Example 1 and the corresponding embodiment is substantially the same, only through the introduction of a gas heater 23, a low pressure gas can be preheated directly and enter the freezer, warmed to break the speed limits and conventional heating equipment, improve the temperature rise performance and increased functionality hyperthermia.

[0087] 实施例3:如图3所示,该气体节流型冷冻外科装置与上述实施例1的基本结构相似,不同在于:本实施例氦气通路与其他低压气体通路分离,并设置独立控制的氦气电磁阀和氦气限压阀,即氦气由所述氦气源12a接入一独立的氨气输入管15,其另一端在第三三通22处连接至所述致热气体总管24,所述氦气输入管15上依次设有所述氦气气压表12b、所述氦气调压阀(12c)、氦气电磁阀16和氦气限压阀17。 [0087] Example 3: As shown, the gas throttling type cryosurgical apparatus of the above embodiment 3 is similar to basic configuration 1, except that: in Example passage of helium with other low-pressure gas passage isolated present embodiment, and is provided independently helium and the helium pressure limiting solenoid valve controlled, i.e., the helium gas from the helium gas source 12a access a separate ammonia inlet tube 15, and the other end connected to the thermal actuator 22 at a third three-way gas manifold 24, in turn provided with a pressure gauge 12b of the helium gas helium inlet pipe 15, the helium gas pressure regulating valve (12c), the solenoid valve 16 and helium helium pressure limiting valve 17.

[0088] 实施例3设置独立的所述氦气限压阀17限压至氦气节流致热工作压力(6.9MPa)。 [0088] Example 3 is provided independent of the helium gas pressure limiting pressure limiting valve 17 to a pressure (of 6.9 MPa) helium expansion pyrogenic work. 而其余低压复温气体可由低压限压阀21限压至任意预设工作压力,不受氦气工作压力的限制,可充分利用节流致热快速复温的效率和提高低压气体的利用率。 While the remaining low-pressure gas may be rewarmed low pressure limiting valve 21 limits the pressure to any pre-set operating pressure, helium gas is not limited by the working pressure, the throttle actuator can take advantage of the rapid rewarming of heat and improve the utilization efficiency of the low-pressure gas.

[0089]实施例3实现的控制方法包括冷冻模式和复温模式: [0089] Example 3 achieved a control method comprising freezing and thawing mode mode:

[0090] 冷冻模式:同实施例1。 [0090] freezing mode: same as in Example 1.

[0091]复温模式:根据复温气体的来源,可分为: [0091] rewarming mode: The gas source rewarming, it can be divided into:

[0092] (1)分流复温模式:同实施例1; [0092] (1) rewarming split mode: the same as Example 1;

[0093] (2)余气复温模式:同实施例1; [0093] (2) the residual gas rewarming mode: the same as Example 1;

[0094] (3)普压复温模式:同实施例1; [0094] (3) Pressure P rewarming mode: the same as Example 1;

[0095] ⑷氦气复温模式:氦气由氦气源12a,经氦气气压表1¾和氦气调压阀12c,接入氦气输入管15,并经氦气电磁阀16和氦气限压阀17,限压至氦气致热工作压力后,经第三三通22,接入致热气体总管24;再经冷冻器加热电磁阀25控制,经所述冷冻器输气管8和所述第四三通26输出至冷冻器进气管9a,实施冷冻器复温操作。 [0095] ⑷ rewarming Helium Mode: helium gas from the helium gas source 12a, and by helium helium 1¾ barometer pressure regulating valve 12c, the access helium inlet tube 15, and helium gas and helium gas through the solenoid valve 16 after the pressure limiting valve 17, to the helium pressure limiting pyrogenic working pressure tee 22 via the third access pyrogenic gas manifold 24; was heated via a solenoid valve 25 controls the freezer, the freezer via pipeline 8 and the output of the fourth three-way intake pipe 26 to the freezer 9a, embodiments freezer thawing operation.

[0096] (5)排气复温模式:同实施例1。 [0096] (5) an exhaust rewarming mode: same as in Example 1.

[0097] 实施例4:如图4所示,在上述实施例3的基础上,所述致热气体总管24上位于所述第三三通22与冷冻器致热电磁阀25之间的管路上设有气体加热器23,使低压复温气体(包括氦气)预热后再输入冷冻器,从而增强复温和加热的效果。 [0097] Example 4: As shown in FIG 3 based on the above-described embodiment, the actuator 4 is located in the hot gas header pipe 22 and the third three-way between the freezer 25 the thermal actuator solenoid valve 24 way a gas heater 23, the low pressure gas rewarming (including helium) after preheating enter the freezer, so as to enhance the heating effect of rewarming.

[0098]实施例4实现的控制方法包括冷冻模式和复温模式,根据复温气体的来源不同复温模式可分为:(1)分流复温模式、(2)余气复温模式、(3)普压复温模式、(4)节流复温模式和(5)排气复温模式,其控制过程与实施例3中对应的方式基本相同,只是通过引入的气体加热器23,可直接预热低压气体并输入冷冻器,突破了现有设备的升温限值和升温速度,提高升温性能和增加了热疗的功能。 [0098] Example 4 implement the control method comprising freezing and thawing mode pattern, depending on the source of rewarming modes rewarming gas may be divided into: (1) rewarming split mode, (2) the residual gas rewarming mode, ( 3) pressure P rewarming mode, (4) throttling mode and rewarming (5) rewarming exhaust mode, which mode control procedure in Example 3 corresponding to the embodiment is substantially the same, but by introducing a gas heater 23, may be direct low pressure gas and preheating enter the freezer, warmed to break the speed limits and conventional heating equipment, improve the temperature rise performance and increased functionality hyperthermia.

[0099] 实施例5:如图5所示,在上述实施例1-4的基础上,所述冷冻器输气管⑻位于所述冷冻器冷冻电磁阀(7)和冷冻器加热电磁阀(25)之间的管段上具有多个串联的所述第四三通(26),每个所述第四三通(26)分别连接一所述冷冻器(9)。 [0099] Example 5: As illustrated in Examples 1-4 based on the above-described embodiment, the freezer is located in the pipeline ⑻ frozen freezer solenoid valve (7) and the freezer 5 heating solenoid valve (25 having a plurality of serially connected between the upper tube section) a fourth three-way (26), each of said fourth three-way (26) are connected to the a freezer (9). 实施例5的控制方法如实施例1-4中任一控制方法基本相同,最终可实现多冷冻器同步冷冻或复温。 Control Example 5 as described in Example 1-4 a control method is basically the same, eventually multi-frozen or freeze-thawing synchronization.

[0100] 实施例6:如图6所示,在上述实施例1-4的基础上,所述冷冻器输气管8及位于其上所述冷冻器冷冻电磁阀7、冷冻器加热电磁阀25、第四三通26、进气管9a和冷冻器9构成了一连接在所述冷冻气体总管6末端与所述致热气体总管24末端之间的组件A,在所述冷冻气体总管6末端与所述致热气体总管24末端之间并联有多个所述的组件A。 [0100] Example 6: 6, based on the above Examples 1-4, the pipeline 8 and the freezer is located on the solenoid valve 7 freezing freezer, a freezer heating solenoid valve 25 , a fourth three-way 26, the intake pipe 9 constitutes a freezer 9a and a connection terminal 6 and the refrigerant gas manifold assembly a between the end 24 of the hot gas manifold actuator, 6 and the end of the freezing gas manifold the actuator assembly has a plurality of parallel between the tip 24 of the hot gas manifold A. 实施例6的控制方法如实施例1-4中任一控制方法基本相同,最终可实现多冷冻器相互独立的冷冻或复温。 Control Example 6 as described in Example 1-4 a control method is basically the same, eventually multi independent freezer or freezing thawing.

[0101] 试验验证: [0101] Test verification:

[0102] (1)排气复温验证:对实施例1技术方案(无气体预热)进行了冷冻排气复温试验验证:首先将美国此&1也1>〇11。3公司制造的2.4111111直径冷冻器连接至该装置,将该冷冻器前端冷冻部分完全浸没于接近体温的36〜37°C恒温水中,温度探针分别置于水中和固定于冷冻器前端;使用高于氩气节流工作压力的25MPa(3500psi)高压氩气源作为高压气源1,高压限压阀5设置在20MPa(2800psi),在室温22°C下开始试验。 [0102] (1) The exhaust rewarming verification: Example 1 aspect (without gas preheating) were freeze-thawing exhaust experimental verification: this first United States & amp; 1 is also 1> 〇11.3 Inc. 2.4111111 diameter of the freezer is connected to the apparatus, the front end portion of the frozen freezer completely near body immersed in a constant temperature water 36~37 ° C, a temperature probe and water were placed in a freezer fixed to the distal end; integrity using the above Ar the stream pressure 25MPa (3500psi) source of high pressure argon gas as a high pressure source 1, the high pressure limiting valve 5 provided at 20MPa (2800psi), start test at room temperature 22 ° C. 先使用“冷冻模式”,开启高压调压阀lc和冷冻器冷冻电磁阀7,高压氩气将冷冻器冷冻至-l〇〇°C并形成正常冰球5分钟后停止冷冻。 First use "freezing mode", the high-pressure regulating valve lc open refrigerating and freezing solenoid valve 7, high pressure argon freezer and frozen to form a normal -l〇〇 puck ° C for 5 minutes to stop freezing. 随即启动“排气复温”工作模式,关闭高压调压阀lc并保持冷冻器冷冻电磁阀7开启,装置内气体逐渐自冷冻器9排出、气压自20MPa(2800psi)下降,在180秒内将冷冻器复温至l〇°C以上。 Then start the "exhaust rewarming" mode of operation, a high pressure regulator valve closing lc frozen and kept frozen solenoid valve 7 is opened, the gas within the device 9 is gradually discharged from the freezer, air pressure from 20MPa (2800psi) down to within 180 seconds freezer thawing to above l〇 ° C. 试验结果如图8所示。 The test results shown in Fig. 本实验证明了排气复温的良好效果。 This experiment proved that good results exhaust rewarming.

[0103] (2)余气复温验证:对实施例1技术方案进行了余气复温试验验证:首先将美国也&1你1'1'〇111(^公司制造的2.4酿直径冷冻器连接至该装置,将该冷冻器前桐冷冻部分完全浸没于接近体温的36〜37。(:恒温水中,室温21°C;温度探针分别置于水中和固定于冷冻器探头前端。使用高于氩气节流工作压力的25MPa (3500psi)高压氩气源作为高压气源1,余气气源l〇a使用低于氩气致冷工作压力的剩余17.5MPa (2500psi)压力氩气并设置低压限压阀21为l2.5MPa(l8〇Opsi)。先使用“冷冻模式”,开启高压调压阀lc和冷冻器冷冻电磁阀7,高压氩气将冷冻器冷冻至-100°C并形成正常冰球5分钟后关闭冷冻器冷冻电磁阀7停止冷冻。 随即启动“余气复温模式”,开启低压电磁阀19和冷冻器加热电磁阀25,限压为12.5MPa (1800psi)的低压氩气将输入冷冻器9,在2〇0秒内将冷冻器9复温至〇°C以上。试验 [0103] (2) the residual gas rewarming verification: the technical solutions of the embodiments 1 were thawed gas experimental verification I: First United States & amp; 1 you 1'1'〇111 (2.4 ^ manufactured frozen stuffed diameter is connected to the device, the front portion of the freezer refrigeration Kazuto completely immersed in near body 36~37 (: water temperature, room temperature 21 ° C; temperature probe are placed in water and fixed to the tip of the probe using the freezer. higher than the operating pressure of argon throttle 25MPa (3500psi) source of high pressure argon gas as a high pressure source 1, the gas sources in l〇a I below using an argon gas pressure of the cooling operation, the remaining 17.5MPa (2500psi) pressure of argon and set low pressure limiting valve 21 is l2.5MPa (l8〇Opsi). first using the "freeze mode", the high-pressure regulating valve lc open refrigerating and freezing solenoid valve 7, high pressure argon freezer and frozen to -100 ° C formed after 5 minutes puck off normal freezer refrigeration freezing solenoid valve 7 is stopped. then start the "residual gas rewarming mode", the low pressure solenoid valve 19 is turned on and the freezer heating solenoid valve 25, pressure limit 12.5MPa (1800psi) low pressure argon freezer input 9, in the second freezer 2〇0 rewarming to 9 ° C above square test 结果如图9所示。本实验证明了余气复温的效果。 The results shown in Figure 9. This experiment demonstrates the effect of residual gas rewarming.

[0104]尽管上面结合图对本发明进行了描述,但是本发明并不局限于上述的具体实施方式,上述的具体实施方式仅仅是示意性的,而不是限制性的,本领域的普通技术人员在本发明的启示下,在不脱离本发明宗旨的情况下,还可以做出很多变形,这些均属于本发明的保护之内。 [0104] While the above in conjunction with FIG. The present invention has been described, but the present invention is not limited to the specific embodiments described above specific embodiments are merely illustrative, and not restrictive, those of ordinary skill in the art the teaching of the present invention, without departing from the spirit of the invention, many variations can be made, which fall within the protection of the present invention.

Claims (9)

1. 一种气体节流型冷冻外科装置,包括高压冷冻气路、低压供气气路、低压致热气路、 分流气路、冷冻器输气管(8)和冷冻器0^); 所述高压冷冻气路包括:与高压气源(la)出气口依次相连的高压气体输入管(2)和冷冻气体总管(6),所述高压气体输入管(2)上设有高压气压表(lb)和高压调压阀(lc),所述高压气体输入管(2)与所述冷冻气体总管(6)的连接处设有高压限压阀(5),所述高压气体输入管⑵上、位于所述高压调压阀(lc)与所述高压限压阀⑸之间的管段上设有第一三通(3); 其特征在于: 所述低压供气气路包括:与高压余气气源(l〇a)相连的余气输出口(10d)、与普压气源(11a)相连的普压输出口(Ud)、与氦气源(12a)相连的氦气输出口(12d);所述高压余气气源(10a)与所述余气输出口(l〇d)的连接处设有余气气压表(l〇b)和余气调压阀(10c);所述普压气源(11a)与 A gas expansion-type cryosurgical apparatus comprises a high pressure refrigeration gas passage, a low pressure gas supply passage, a low pressure induced hot gas path, the gas bypass passage, freezer pipeline (8) and the freezer ^ 0); the high-pressure refrigerating circuit comprises: a high pressure air source (La) is connected to a high pressure gas outlet are sequentially input tube (2) and the refrigerant gas manifold (6), the high pressure gas supply line (2) is provided with a high-pressure gauge (LB) and pressure regulating valve (LC), the high pressure gas supply line (2) connected to the refrigerant gas at the manifold (6) is provided with a high pressure limiting valve (5), the high pressure gas inlet pipe ⑵, located the high-pressure regulator valve (LC) and the upper pipe section between the high-pressure limiting valve is provided ⑸ first three (3); characterized in that: said low pressure air supply manifold comprising: a gas with a high pressure residual air source (l〇a) connected to the residual gas outlet (10d), and the pressure air source P (11a) connected to the output port of the pressure P (Ud), the helium gas source (12a) connected to the helium outlet (12 d) ; the high-pressure gas than air source (10a) and the residual gas outlet (l〇d) is connected with the residual gas at a gauge (l〇b) and residual gas pressure regulating valve (1OC); the pressure P gas source (11a) and 普压输出口(lid)的连接处设有普压气压表(11b)和普压调压阀(11c);所述氦气源(12a)与所述氦气输出口(12d)的连接处设有氦气气压表(12b)和氦气调压阀(12c); 所述低压致热气路包括:低压汇流气管(20)和致热气体总管(24),所述低压汇流气管(20)的一端为低压气体输入口(18),所述余气输出口(10d)、所述普压输出口(Ud)和所述氦气输出口(12d)与所述低压气体输入口(18)之间均为可拆卸连接;所述低压汇流气管(20)的另一端与所述致热气体总管(24)相连;所述低压汇流气管(20)上设有低压电磁阀(19)和低压限压阀(21),所述低压汇流气管(20)上、位于所述低压电磁阀(19)和所述低压限压阀(21)之间的管段上设有第二三通⑷; 所述第一三通(3)与所述第二三通⑷之间连接有分流气管(13),所述分流气管(13)上设有分流电磁阀(14),所述分流气管(13)和所述分流电磁阀 Poor pressure output port (LID) is connected to the pressure gauge provided Pu (11b) and Pu pressure adjustment valve (11c); said helium source (12a) and the helium gas outlet (12 d) is connected at helium with pressure gauge (12b) and helium pressure regulating valve (12c); the low-pressure hot gas path actuator comprising: a bus a low pressure pipe (20) and pyrogenic gas manifold (24), the low-voltage bus duct (20) one end of a low pressure gas inlet (18), the residual gas outlet (1Od), the outlet pressure P (Ud) and the helium gas outlet (12 d) with the low-pressure gas inlet (18) detachable connection between both; the other end of the low-voltage bus duct (20) is connected to the pyrogenic gas manifold (24); with the low pressure solenoid valve (19) and a low-voltage bus on the pipe (20) the pressure-limiting valve (21), the low-voltage bus duct (20), positioned with the second section of pipe tee ⑷ the low pressure solenoid valve (19) and the low pressure-limiting valve (21); the said first three (3) connected between the shunt and the second three-way ⑷ pipe (13), said diverter bypass pipe is provided with a solenoid valve (14) (13), said bypass pipe (13) and said bypass solenoid valve 14)构成了所述分流气路; 所述冷冻器输气管(8)连接在所述冷冻气体总管(6)的末端与所述致热气体总管(24) 的末端之间,并通过第四三通(26)连接至所述冷冻器进气管(9a),所述冷冻器进气管(9a) 与所述冷冻器⑼相连;所述冷冻器输气管⑻上、位于所述冷冻气体总管⑹的末端与所述第四三通(26)之间的管路上设有冷冻器冷冻电磁阀(7),所述冷冻器输气管(8)上、位于所述致热气体总管(24)的末端与所述第四三通(26)之间的管路上设有冷冻器加热电磁阀(25)。 14) constituting said bypass air passage; the freezer pipeline (8) connected between the hot end of the actuation gas manifold (24) of the end of the freezing gas manifold (6) and through the fourth tee (26) connected to the intake pipe freezer (9a), said freezer intake pipe (9a) is connected to the freezer ⑼; the freezer pipeline ⑻, the refrigerant gas manifold positioned ⑹ end of the fourth pipeline provided between the tee (26) freezer refrigeration solenoid valve (7), said freezer pipeline (8), located in said pyrogenic gas manifold (24) and the line between the end of the fourth three-way (26) provided with a heating freezer solenoid valve (25).
2. —种气体节流型冷冻外科装置,包括高压冷冻气路、低压供气气路、低压致热气路、 分流气路、冷冻器输气管⑻和冷冻器(9); 所述高压冷冻气路包括:与高压气源(la)出气口依次相连的高压气体输入管(2)和冷冻气体总管(6),所述高压气体输入管(2)上设有高压气压表(lb)和高压调压阀(lc),所述高压气体输入管(2)与所述冷冻气体总管(6)的连接处设有高压限压阀(5),所述高压气体输入管⑵上、位于所述高压调压阀(lc)与所述高压限压阀⑸之间的管段上设有第一三通(3); 其特征在于: 所述低压供气气路包括:与高压余气气源(l〇a)相连的余气输出口(l〇d)、与普压气源(1 la)相连的普压输出口(1 Id)、与氦气源(12a)相连的氦气输入管(15);所述高压余气气源(10a)与所述余气输出口(l〇d)的连接处设有余气气压表(l〇b)和余气调压阀(10c);所述普压气源(11a)与 2. - gases throttling type cryosurgical apparatus comprises a high pressure refrigeration gas passage, a low pressure gas supply passage, a low pressure induced hot gas path, the gas bypass passage, a freezer and freeze ⑻ pipeline (9); the high-pressure refrigerating gas Road, comprising: a high pressure air source (La) is connected to a high pressure gas outlet are sequentially input tube (2) and the refrigerant gas manifold (6), the high pressure gas supply line (2) is provided with a high-pressure gauge (LB) and high pressure pressure regulating valve (LC), the high pressure gas supply line (2) and the refrigerant gas manifold (6) is provided at the high pressure is connected pressure limiting valve (5), the high pressure gas inlet pipe ⑵, located a high pressure regulating valve (LC) and the upper pipe section between the high-pressure limiting valve is provided ⑸ first three (3); characterized in that: said low voltage supply circuit comprises: a high pressure residual gas and a gas source ( l〇a) residual gas outlet (l〇d) connected with the pressure air source P (1 la) pressure output port P (1 Id) is connected with the helium source (12a) connected to the helium supply line ( 15); the high-pressure gas than air source (10a) and the residual gas outlet (l〇d) is connected with the residual gas at a gauge (l〇b) and residual gas pressure regulating valve (1OC); the Pu pressure gas source (11a) and 压输出口(lid)的连接处设有普压气压表(llb)和普压调压阀(llc);所述氦气输入管(15)上设有氦气气压表(12b)、氦气调压阀(12c)、氦气电磁阀(16)和氦气限压阀(17); 所述低压致热气路包括:低压汇流气管(20)和致热气体总管(24),所述低压汇流气管(2〇)的一端为低压气体输入口(18),所述余气输出口(i〇d)和所述普压输出口(lid)与所述低压气体输入口(18)之间均为可拆卸连接;所述低压汇流气管(20)的另一端通过第三三通(22)与所述致热气体总管(24)相连,同时,所述氦气输入管(15)通过所述第三三通(22)接入致热气体总管(24); 所述低压汇流气管(20)上设有低压电磁阀(19)和低压限压阀(21),所述低压汇流气管(20)上:在位于所述低压电磁阀(19)和低压限压阀(21)之间的管段上设有第二三通(4),在位于所述低压限压阀(21) 所述第一三通(3)与所述第二三通⑷之间 Pressure output port (LID) is connected to the pressure gauge provided Pu (LLB) and a pressure regulating valve P (LLC); the helium gas inlet pipe is provided with helium gas pressure gauge (12b) (15), helium pressure regulating valve (12c), helium solenoid valve (16), and helium pressure limiting valve (17); the low-pressure hot gas path actuator comprising: a bus a low pressure pipe (20) and pyrogenic gas manifold (24), said low pressure One end of the bus duct (2〇) low pressure gas between the residual gas outlet (i〇d) and the outlet pressure P (LID) and the low pressure gas inlet (18) input (18), are detachably connected; another end of the low-voltage bus duct (20) connected to the actuator of the hot gas manifold (24) via a third three-way (22), at the same time, the helium gas inlet tube (15) by the said third three-way (22) access pyrogenic gas manifold (24); with the low pressure solenoid valve (19) on the low-voltage bus duct (20) and a low pressure-limiting valve (21), the low-voltage bus duct ( 20): with a second three-way (4) in the pipe section located between the low pressure solenoid valve (19) and a low pressure-limiting valve (21), located in the low pressure-limiting valve (21) between the first three (3) and the second three-way ⑷ 接有分流气管(13),所述分流气管(13)上设有分流电磁阀(14),所述分流气管(13)和所述分流电磁阀(14)构成了所述分流气路; 所述冷冻器输气管(8)连接在所述冷冻气体总管(6)的末端与所述致热气体总管(24) 的末端之间,并通过第四三通(26)连接至冷冻器进气管(9a),所述冷冻器进气管(9a)与所述冷冻器⑼相连;所述冷冻器输气管(8)上、位于所述冷冻气体总管⑹的末端与所述第四三通(26)之间的管路上设有冷冻器冷冻电磁阀(7),所述冷冻器输气管(8)上、位于所述致热气体总管(24)的末端与所述第四三通(26)之间的管路上设有冷冻器加热电磁阀(¾)。 Connected with the shunt pipe (13), said bypass solenoid valve is provided with diverter (14) on the pipe (13), said bypass pipe (13) and said bypass solenoid valve (14) constituting said bypass air passage; the said freezer pipeline (8) connected between the hot end of the actuation gas manifold (24) of the end of the freezing gas manifold (6) and connected to the intake pipe through a freezer fourth three-way (26) (9a), said freezer intake pipe (9a) is connected to the freezer ⑼; the freezer pipeline (8), located at the end of the freezing gas manifold ⑹ with the fourth three-way (26 ) line between the solenoid valve provided with a refrigerating freezer (7), said freezer pipeline (8), at the end of the hot gas manifold actuator (24) and the fourth three-way (26) line between the solenoid valve provided with a heating freezer (¾).
3. 根据权利要求1或2所述气体节流型冷冻外科装置,其特征在于,所述致热气体总管(24)的末端设有气体加热器(23)。 3. The gas throttling type 1 or 2 cryosurgical apparatus according to claim, wherein said actuator end of the hot gas manifold (24) is provided with a gas heater (23).
4. 根据权利要求1或2所述气体节流型冷冻外科装置,其特征在于,所述冷冻器输气管(8)位于所述冷冻器冷冻电磁阀(7)和冷冻器加热电磁阀(25)之间的管段上具有多个串联的所述第四三通(26),每个所述第四三通(26)均分别连接有冷冻器进气管(9a),所述冷冻器进气管(9a)连接有冷冻器(9)。 1 or 2 according to the type cryosurgical gas throttle device according to claim, wherein said freezer pipeline (8) located in said freezer refrigeration solenoid valve (7) and the freezer heating solenoid valve (25 the fourth three-way having a plurality of serially connected between the upper tube section) (26), each of said fourth three-way (26) are connected to each intake pipe freezer (. 9A), the intake pipe freezer (9a) is connected to the freezer (9).
5. 根据权利要求1或2所述气体节流型冷冻外科装置,其特征在于,所述冷冻器输气管(8)、所述冷冻器冷冻电磁阀(7)、所述冷冻器加热电磁阀(25)、所述第四三通(26)、所述进气管(9a)和所述冷冻器(9)构成了连接在所述冷冻气体总管(6)末端与所述致热气体总管(24)末端之间的组件A;所述冷冻气体总管(6)末端与所述致热气体总管(24)末端之间并联有多个所述的组件A。 1 or 2 according to the type cryosurgical gas throttle device according to claim, wherein said freezer pipeline (8), said refrigeration freezer solenoid valve (7), the heating solenoid valve freezer (25), the fourth three-way (26), the intake pipe (9a) and the freezer (9) constitutes a connection (6) the end of the freezing gas manifold pyrogenic gas manifold ( 24) between the ends of the component a; the refrigerant gas manifold (6) and the tip end of the actuator in parallel between the hot gas manifold (24) has a plurality of said components A.
6. 根据权利要求1或2所述气体节流型冷冻外科装置,其特征在于,所述冷冻器(9)为利用气体的焦耳-汤姆逊节流效应产生低温的气体节流致冷型冷冻器。 1 or 2 according to the type cryosurgical gas throttle device according to claim, characterized in that the freezer (9) for the gas using Joule - Thomson throttling effect produced cryogenic gas expansion refrigeration type refrigerator device. _ _
7. 根据权利要求1或2所述气体节流型冷冻外科装置,其特征在于,所述高压气源(la) 是节流膨胀致冷型气体中的一种或几种之混合物;所述高压气源(la)、所述高压余气气源(l〇a)、所述普压气源(11a)和所述氦气源(12a)来自于气瓶、气罐、气泵、杜瓦罐和压缩机中的任何一处。 1 or 2 according to the type cryosurgical gas throttle device according to claim, wherein said high pressure air source (La) is a mixture of one or more throttling expansion of the refrigerant gas type; the high pressure air source (La), the high-pressure gas than air source (l〇a), the air pressure P (11a) and said helium source (12a) from a cylinder, tank, pump, Dewar any tank and a compressor.
8. —种气体节流型冷冻外科装置的控制方法,其特征在于: 利用如权利要求1及3至7的任一所述气体节流型冷冻外科装置,并包括以下一种或多种复温方式: 、 (1)分流复温方式:开启高压调压阀(lc)、分流电磁阀(14)和冷冻器加热电磁阀(25), 同时关闭低压电磁阀(19)和冷冻器冷冻电磁阀⑺;复温气体由所述高压气体输入管⑵上所述第一三通(3)引出,经所述分流气管(1¾和所述分流电磁阀(14),通过所述第二三通(4),接入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管G4),由所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管⑻和所述第四三通(26)输出至所述冷冻器(9),通过热交换实现复温操作,当冷冻器温度达到(TC至正常体温时或所述气压表(lb)显示气压降至1个大气压时,结束该分流复温; ⑵余气复温方式: 将所 8 - The method of controlling the throttling type gases cryosurgical apparatus, wherein: the use as claimed in claim and a throttling type gas cryosurgical apparatus according to any one of 3 to 7, and comprising one or more complex isothermal manner: (1) shunt rewarming: opening a high pressure regulating valve (LC), bypass solenoid valve (14) and the freezer heating solenoid valve (25), while closing the low pressure solenoid valve (19) and a freezer refrigeration solenoid ⑺ valve; rewarming gas (3) leads from the first three-input on the high pressure gas pipe ⑵, via the shunt pipe (1¾ and the diverter solenoid valve (14), through the second three-way (4), the low-voltage bus access pipe (20), through the low pressure-limiting valve (21) pressure limiting access to the gas manifold pyrogenic G4), heated by the freezer solenoid valve (25) control, outputs the freezer and the fourth three-way ⑻ pipeline (26) to the chiller (9), to achieve heat exchange rewarming operation, when the freezer temperature reaches (TC to normal body temperature or the gauge (LB) is displayed when the pressure dropped to 1 atm, the end of the shunt rewarming; ⑵ gas rewarming I: the 余气输出口(l〇d)与所述低压气体输入口(18)连接,同时,所述普压输出口(lid)和所述氦气输出口(12d)均不与所述低压气体输入口(18)连接;开启余气调压阀(10c)、低压电磁阀(19)和冷冻器加热电磁阀(25),同时关闭分流电磁阀(14)和冷冻器冷冻电磁阀(7);复温气体自所述高压余气气源(10a),经所述余气气压表(l〇b)和所述余气调压阀(10c)调控,由所述余气输出口(10d)接入所述低压气体输入口(18),再经所述低压电磁阀(19),接入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管(24),由所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管⑻和所述第四三通(26)输出至所述冷冻器(9),通过热交换实现复温操作,当冷冻器温度达到0°C至正常体温时或所述余气气压表(l〇b)显示气压降至1个大气压时,结束该余气复温; ⑶普压复 Residual gas outlet (l〇d) and the low pressure gas inlet (18), while the outlet pressure P (LID) and the helium gas outlet (12 d) are not input to the low-pressure gas port (18); open air over the regulating valve (1OC), a low pressure solenoid valve (19) and the freezer heating solenoid valve (25) while closing the bypass solenoid valve (14) and a freezer refrigeration solenoid valve (7); rewarming from the high-pressure gas than air gas source (10a), via the residual gas pressure gauge (l〇b) and the residual gas pressure control valve (10c) regulated by the residual gas outlet (1Od) access to the low-pressure gas inlet (18), and then through the low pressure solenoid valve (19), bus access to the low-pressure pipe (20), through the low pressure-limiting valve (21) pressure limiting access by pyrogenic said gas manifold (24), heated by the freezer solenoid valve (25) controlled by the output of the freezer and the fourth three-way ⑻ pipeline (26) to the chiller (9), rewarming achieved by heat exchange operation, when the freezer temperature reaches 0 ° C to normal body temperature or the residual gas pressure gauge (l〇b) displayed when the pressure dropped to 1 atm, the end of the residual gas rewarming; ⑶ P pressure complex 方式: 将所述普压输出口(1 Id)与所述低压气体输入口(18)连接,同时,所述余气输出口(10d)和所述氦气输出口(12d)均不与所述低压气体输入口(18)连接;开启普压调压阀(11c)、低压电磁阀(19)和冷冻器加热电磁阀(25),同时关闭分流电磁阀(14)和冷冻器冷冻电磁阀(7);复温气体自所述普压气源(11a),经所述普压气压表(Ub)和所述普压调压阀(11c)调控,由所述普压输出口(lid)接入所述低压气体输入口(18),再经所述低压电磁阀(19),接入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管(24),由所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管⑻和所述第四三通(26)输出至所述冷冻器(9),通过热交换实现复温操作,当冷冻器温度达到0°C至正常体温时或所述普压气压表(lib)显示气压降至1个大气压时,结束该普压复温; (4) Mode: the pressure output port P (1 Id) and the low pressure gas inlet (18), while the residual gas outlet (1Od) and the helium gas outlet (12 d) and are not said low pressure gas inlet (18); Pu pressure adjustment valve opening (11c), a low pressure solenoid valve (19) and the freezer heating solenoid valve (25) while closing the bypass solenoid valve (14) and a freezer refrigeration solenoid valve (7); rewarming gas pressure P from the gas source (11a), via said pressure gauge P (Ub) and the pressure regulating valve P (11c) regulated by the outlet pressure P (lid ) access to the low-pressure gas inlet (18), and then through the low pressure solenoid valve (19), bus access to the low-pressure pipe (20), through the low pressure-limiting valve (21) pressure limiting access the pyrogenic gas manifold (24), heated by the freezer solenoid valve (25) controlled by the output of the freezer and the fourth three-way ⑻ pipeline (26) to the freezer (9) , by heat exchange achieved rewarming operation, when the freezer temperature reaches 0 ° C to normal body temperature or when the pressure gauge P (lib) displays a reduced pressure atmosphere, the end of the pressure P rewarming; (4) 流复温方式: 将所述氦气输出口(12d)与所述低压气体输入口(18)连接,同时,所述余气输出口(10d)和所述普压输出口(lid)均不与所述低压气体输入口(18)连接;开启氦气调压阀(12c)、低压电磁阀(19)和冷冻器加热电磁阀(25),同时关闭分流电磁阀(14)和冷冻器冷冻电磁阀(7);氦气由所述氦气源(12a),经所述氦气气压表(12b)和氦气调压阀(12〇)调控,由氦气输出口(12d),接至低压气体输入口(18),再经低压电磁阀(19),汇入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管(24);由所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管(8)和所述第四三通(26)输出至所述冷冻器(9),此节流复温气体在冷冻器进气管9a末端JT 口9c处节流膨胀至膨胀腔9d时放热致热,经相邻的冷冻器外壁9e为周围组织复温;当冷冻器温度达到〇°C至正常体温 Flow rewarming: the helium gas outlet (12 d) with the low-pressure gas inlet (18), while the residual gas outlet (1Od) and the outlet pressure P (LID) none connected to the low pressure gas inlet (18); open helium pressure regulating valve (12c), a low pressure solenoid valve (19) and the freezer heating solenoid valve (25) while closing the bypass solenoid valve (14) and a freezer refrigeration a solenoid valve (7); the helium gas from the helium source (12a), via the helium gas pressure gauge (12b) and helium pressure regulating valve (12〇) regulated by the helium gas outlet (12 d), then to the low pressure gas inlet (18), then through the low pressure solenoid valve (19), to import the low-voltage bus duct (20), through the low pressure-limiting valve (21) pressure limiting access to the hot gas manifold actuator (24); (25) controlled by said solenoid valve heating freezer, the freezer via pipeline (8) and the fourth three-way (26) is output to the freezer (9), this throttle rewarming freezer gas intake pipe 9a 9c end JT throttling expansion to the mouth of the exothermic heat induced expansion chamber 9d, through 9e adjacent to the outer wall of the freezer surrounding tissue rewarming; square when the freezer temperature reaches ° C to normal body temperature 时或所述氮气气压表(12b) 显示气压降至1个大气压时,结束该节流复温; ⑸排气复温方式,包括以下两种情形之一: 、 一是,在节流冷冻操作后,关闭所述高压调压阀(lc)并同时开启冷冻电磁阀(7),所述高压冷冻气路中积存的冷冻气体将持续通入冷冻器(9),直至冷冻器温度达到o°c至正常体温时或所述高压气压表(lb)显示气压降至1个大气压时,结束排气复温; 二是,复温操作后关闭所述余气调压阀(l〇c)、所述普压调压阀(11c)和所述氦气调压阀(12c),开启所述低压电磁阀(19)和所述冷冻器致热电磁阀(¾),所述低压管路中剩余致热气体将持续通入所述冷冻器(9),直至冷冻器温度达到〇°C至正常体温时或所有气压表显示气压降至1个大气压时,结束排气复温。 Or when the nitrogen pressure gauge (12b) show a reduced pressure atmosphere, the end of the throttle rewarming; ⑸ exhaust rewarming, comprises one of the following two situations: First, in the freezing operation throttling after closing the high-pressure regulating valve (LC) and frozen simultaneously turned solenoid valve (7), the high-pressure refrigerating gas passage of refrigerating gas will continue into the freezer (9), until the freezer temperature reaches o ° when normothermic or c to the high-pressure gauge (LB) show a reduced pressure atmosphere, exhaust end of rewarming; second, closing the residual gas pressure regulating valve (l〇c) after rewarming operation, Pu said pressure adjustment valve (11c) and said helium pressure control valve (12c), said low pressure opening the solenoid valve (19) and the freezer pyrogenic solenoid valve (¾), the low pressure line pyrogenic remaining gas will continue into the freezer (9), until the freezer temperature reaches square ° C to normal body temperature or pressure display all gauge to 1 atm, the end of the exhaust rewarming.
9. 一种气体节流型冷冻外科装置的控制方法,其特征在于:利用如权利要求2及3至7的任一所述气体节流型冷冻外科装置,并包括以下一种或多种复温方式: (1)分流复温方式:开启高压调压阀(lc)、分流电磁阀(14)和冷冻器加热电磁阀(25), 同时关闭低压电磁阀(19)和冷冻器冷冻电磁阀(7);复温气体由所述高压气体输入管⑵上所述第一三通(3)引出,经所述分流气管(13)和所述分流电磁阀(14),通过所述第二三通(4),接入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管(24) ,由所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管⑻和所述第四三通(26)输出至所述冷冻器(9),通过热交换实现复温操作,当冷冻器温度达到(TC至正常体温时或所述高压气压表(lb)显示气压降至1个大气压时,结束该分流复温; ⑵余气复温方式: 将所 9. A method of controlling a gas type throttle cryosurgical apparatus, wherein: said gas throttling a cryosurgical apparatus type claims 2 and 3-7 use as claimed in claim, and comprising one or more complex temperature: (1) shunt rewarming: opening a high pressure regulating valve (LC), bypass solenoid valve (14) and the freezer heating solenoid valve (25), while closing the low pressure solenoid valve (19) and a freezer refrigeration solenoid valve (7); rewarming gas (3) leads from the first three-input on the high pressure gas pipe ⑵, via the shunt pipe (13) and said bypass solenoid valve (14), through the second a three-way (4), the low-voltage bus access pipe (20), through the low pressure-limiting valve (21) pressure limiting access the pyrogenic gas manifold (24) by heating the freezer solenoid valve (25) controlled by the output of the freezer and the fourth three-way ⑻ pipeline (26) to the chiller (9), to achieve heat exchange rewarming operation, when the freezer temperature reaches (TC to normal or when the temperature of the high-pressure gauge (LB) show the air pressure to 1 atm, the end of the shunt rewarming; ⑵ gas rewarming I: the 述余气输出口(l〇d)与所述低压气体输入口(18)连接,同时,所述普压输出口(lid)不与所述低压气体输入口(18)连接,开启余气调压阀(10c)、低压电磁阀(19)和冷冻器加热电磁阀(25),同时关闭分流电磁阀(14)和冷冻器冷冻电磁阀(7);复温气体自所述高压余气气源(l〇a),经所述余气气压表(l〇b)和所述余气调压阀(l〇c)调控,由所述余气输出口(10d)接入所述低压气体输入口(18),再经所述低压电磁阀(19),接入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管(24),由所述冷冻器加热电磁阀(25) 控制,经所述冷冻器输气管(8)和所述第四三通(26)输出至所述冷冻器(9),通过热交换实现复温操作,当冷冻器温度达到〇°C至正常体温时或所述余气气压表(l〇b)显示气压降至1个大气压时,结束该余气复温; ⑶普压复温方式: 将所述 Said residual gas outlet (l〇d) and the low pressure gas inlet (18), while the outlet pressure P (LID) not connected to the low pressure gas inlet (18), open atmosphere I pressure valve (1OC), a low pressure solenoid valve (19) and the freezer heating solenoid valve (25) while closing the bypass solenoid valve (14) and a freezer refrigeration solenoid valve (7); rewarming gas from the high-pressure gas remaining gas source (l〇a), via the residual gas pressure gauge (l〇b) and the residual gas pressure regulating valve (l〇c) regulated by the residual gas outlet (1Od) to access the low-pressure gas the input port (18), and then through the low pressure solenoid valve (19), bus access to the low-pressure pipe (20), through the low pressure-limiting valve (21) pressure limiting access the pyrogenic gas manifold ( 24), (25) is controlled by the heating solenoid valve freezer, the freezer via pipeline (8) and the fourth three-way (26) is output to the freezer (9), is achieved by heat exchange rewarming operation, when the freezer temperature reaches square ° C to normal body temperature or the residual gas pressure gauge (l〇b) displayed when the pressure dropped to 1 atm, the end of the residual gas rewarming; ⑶ rewarming pressure P : the 压输出口(lid)与所述低压气体输入口(18)连接,同时,所述余气输出口(10d)不与所述低压气体输入口(18)连接,开启普压调压阀(11c)、低压电磁阀(19)和冷冻器加热电磁阀(25),同时关闭分流电磁阀(14)和冷冻器冷冻电磁阀(7);复温气体自所述普压气源(11a),经所述普压气压表(lib)和所述普压调压阀(11c)调控,由所述普压输出口(lid)接入所述低压气体输入口(18),再经所述低压电磁阀(19),接入所述低压汇流气管(20),经所述低压限压阀(21)限压,接入所述致热气体总管(24),由所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管(8)和所述第四三通(26)输出至所述冷冻器(9),通过热交换实现复温操作,当冷冻器温度达到(TC至正常体温时或所述普压气压表(Ub)显示气压降至1个大气压时,结束该普压复温; ⑷节流复温方式: 开启氦气调压阀(12c)、氦气 Pressure output port (LID) and the low pressure gas inlet (18), while the residual gas outlet (1Od) not connected to the low pressure gas inlet (18), Pu pressure adjustment valve opening (11c ), a low pressure solenoid valve (19) and the freezer heating solenoid valve (25) while closing the bypass solenoid valve (14) and a freezer refrigeration solenoid valve (7); rewarming gas pressure P from the gas source (11a), via the pressure gauge P (lib) and said pressure regulating valve P (11c) regulated by the outlet pressure P (LID) to access the low-pressure gas inlet (18), and then through the low pressure a solenoid valve (19), bus access to the low-pressure pipe (20), through the low pressure-limiting valve (21) pressure limiting access the pyrogenic gas manifold (24), heated by the solenoid valve freezer (25) controlled by the output of the freezer pipeline (8) and the fourth three-way (26) to the chiller (9), to achieve heat exchange rewarming operation, when the freezer temperature reaches (TC to normal body temperature or when the pressure gauge P (Ub) is displayed when the pressure dropped to 1 atm, the end of the pressure P rewarming; ⑷ throttle rewarming: open helium pressure regulating valve (12c), helium 磁阀(1(3)和冷冻器加热电磁阀(25),同时关闭低压电磁阀(19)、分流电磁阀(14)和冷冻器冷冻电磁阀(7);氦气由所述氦气源(12a),经所述氦气气压表(12b)和所述氦气调压阀(12c),接入所述氦气输入管(15),并经所述氦气电磁阀(I6) 和所述氦气限压阀(n),经所述第三三通(22),接入所述致热气体总管(24);再经所述冷冻器加热电磁阀(25)控制,经所述冷冻器输气管⑻和所述第四三通(26),输出至所述冷冻器(9),在其内部通过节流膨胀放热而实现复温操作,当冷冻器温度达到(TC至正常体温时或所述氮气气压表(12b)显示气压降至1个大气压时,结束该节流复温; ⑸排气复温方式,包括以下两种情形之一: 一是,在节流冷冻操作后,关闭所述高压调压阀(lc)并同时开启冷冻电磁阔(7),所述高压冷冻气路中积存的冷冻气体将持续通入冷冻器(9),直至冷冻器温 The solenoid valve (1 (3) and the freezer heating solenoid valve (25), while closing the low pressure solenoid valve (19), bypass solenoid valve (14) and a freezer refrigeration solenoid valve (7); the helium from the helium gas source (12a), via the helium gas pressure gauge (12b) and said helium pressure control valve (12c), access to the helium supply line (15), and helium through the solenoid valve (I6 of) and the helium pressure limiting valve (n-), via said third three-way (22), said access pyrogenic gas manifold (24); and then through the freezer heating control solenoid valve (25), by the ⑻ said freezer and the fourth three-way pipeline (26), to the output of the chiller (9), rewarming operation is achieved by throttling expansion in the interior heat, when the temperature reaches freezer (TC to normal body temperature or nitrogen pressure gauge (12b) is displayed when the pressure dropped to 1 atm, the end of the throttle rewarming; ⑸ exhaust rewarming, comprises one of the following two situations: First, a throttle in the freezing after the operation, the high-pressure regulating valve to close (LC) and simultaneously open the electromagnetic frozen width (7), the high-pressure refrigerating gas passage of refrigerating gas will continue into the freezer (9), until the freezer temperature 度达到〇°C至正常体温时或所述高压气压表(lb)显示气压降至1个大气压时,结束排气复温; 一二是,复温操作后关闭所述余气调压阀(l〇c)、所述普压调压阀(llc)和所述氦气调压阀(12c),开启所述低压电磁阀(19)、所述氦气电磁阀(16)和所述冷冻器致热电磁阀(25)^ 所述低压管路中剩余致热气体将持续通入所述冷冻器(9),直至冷冻器温度达到0 C至正帛体温时或所有气压表显示气压降至1个大气压时,结束排气复温。 When reaches square ° C to normal body temperature or the high-pressure gauge (LB) is displayed when the pressure dropped to 1 atm, the end of the exhaust rewarming; twelve is the residual gas pressure control valve to close after rewarming operation ( l〇c), said pressure regulating valve Pu (LLC) and the helium pressure control valve (12c), said low pressure opening the solenoid valve (19), the helium gas solenoid valve (16) and the freezing when the thermal actuator is a solenoid valve (25) of the low-pressure line ^ pyrogenic remaining gas will continue into the freezer (9), until the temperature reaches 0 C freezer temperature silk or all of the positive pressure drop gauge display to 1 atm, the end of the exhaust rewarming.
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