CN109481003A - A kind of low temperature nitrogen Cryoablation system - Google Patents
A kind of low temperature nitrogen Cryoablation system Download PDFInfo
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- CN109481003A CN109481003A CN201811653532.XA CN201811653532A CN109481003A CN 109481003 A CN109481003 A CN 109481003A CN 201811653532 A CN201811653532 A CN 201811653532A CN 109481003 A CN109481003 A CN 109481003A
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title claims abstract description 244
- 229910052757 nitrogen Inorganic materials 0.000 title claims abstract description 122
- 239000007789 gas Substances 0.000 claims abstract description 85
- 239000007788 liquid Substances 0.000 claims abstract description 74
- 230000008014 freezing Effects 0.000 claims abstract description 34
- 238000007710 freezing Methods 0.000 claims abstract description 34
- 239000000523 sample Substances 0.000 claims abstract description 29
- 238000010438 heat treatment Methods 0.000 claims abstract description 23
- 238000001816 cooling Methods 0.000 claims description 23
- 238000005192 partition Methods 0.000 claims description 20
- 238000004064 recycling Methods 0.000 claims description 17
- 238000004134 energy conservation Methods 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001276 controlling effect Effects 0.000 description 11
- 230000000694 effects Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- 238000002679 ablation Methods 0.000 description 2
- 238000002681 cryosurgery Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- 238000005057 refrigeration Methods 0.000 description 2
- 238000004781 supercooling Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 239000000112 cooling gas Substances 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000002207 thermal evaporation Methods 0.000 description 1
- 238000009834 vaporization Methods 0.000 description 1
- 230000008016 vaporization Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00714—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Abstract
The present invention provides a kind of low temperature nitrogen Cryoablation system, including sequentially connected liquid nitrogen container, gas transfer pipeline, connection component and work probe, the air shooter road is equipped with corresponding air pump and valve, it is characterized by: being equipped with liquid nitrogen evaporator in the liquid nitrogen container, liquid nitrogen container is equipped with safety relief valve, pressure sensor and temperature sensor, and the air shooter road is equipped with heating and temperature controlling device.Due to the adoption of the above technical scheme, liquid nitrogen is converted into low temperature nitrogen by this system or low temperature gas-liquid mixture is delivered to freezing region, solves the problems, such as that the gas during the output of liquid nitrogen frozen equipment is stifled, and realize rewarming using return-air heating, energy conservation and environmental protection is practical.
Description
Technical field
The invention belongs to medical instruments fields, more particularly, to a kind of low temperature nitrogen Cryoablation system.
Background technique
Cryosurgery treatment is to damage in method and human history with ablation lesion tissue to make earliest using ultralow temperature
Pathological tissues ablation techniques.From nineteen sixty American Psychiatry surgeon Irving Cooper and engineer Arnold Lee
Probe shape liquid nitrogen freezing apparatus is invented and for using liquid nitrogen as the liquid nitrogen frozen of cryogenic fluid (refrigerant) after freezing brain tissue
Surgical device is applied to treat various tumours.
The convenience that liquid nitrogen has about -196 DEG C of ideal low temperature and is easy to get.It is visited when it is transported to freezing
When probe freeze space (target area) of needle, heat promptly can be absorbed from probe surrounding tissue and gasified, generated in probe strong
Big cooling effect.But liquid nitrogen in capillary transport pipeline reach probe before because by thermal evaporation blocking pipeline when, will lead to " gas
It is stifled " effect.The stifled effect of gas will cause liquid nitrogen conveying to interrupt, liquid nitrogen can not reach probe freeze space, cryosurgery can not carry out.
Therefore, how to overcome " gas the is stifled " phenomenon of liquid nitrogen in capillary transmission process, manufacture a kind of reliable and stable, refrigeration
The good equipment of effect is the emphasis of cryogenic freezing ablating device research.
Summary of the invention
Traditional liquid nitrogen frozen equipment is usually to convey liquid nitrogen to the freezing region of cryoprobe, but very thin for diameter
For cryoprobe, the capillary pipeline of liquid nitrogen conveying often leads to the problem of gas and blocks up, and operation is caused to interrupt even failure.This system is
It solves the problems, such as that the gas during liquid nitrogen plant output is stifled, liquid nitrogen is directly changed into the low temperature nitrogen of good fluidity or gas-liquid is mixed
It closes object and is delivered to freezing region；And rewarming is heated using return-air.In order to achieve the above object, this system uses following technical side
Case:
A kind of low temperature nitrogen Cryoablation system, including sequentially connected liquid nitrogen container, gas transfer pipeline and work probe,
The gas transfer pipeline includes frozen gas transfer pipeline and rewarming gas transfer pipeline, is equipped with liquid nitrogen in the liquid nitrogen container and steams
Device is sent out, liquid nitrogen container is equipped with pressure sensor, safety relief valve and temperature sensor, and the rewarming air shooter road is equipped with
Heating and temperature controlling device.
Further, preferably, gas gathering mask and entrance are additionally provided in the liquid nitrogen container to be connected to the gas gathering mask
Cooling coil, the outlet of the cooling coil is connected to the frozen gas transfer pipeline；The gas gathering mask also with it is described multiple
Warm gas transfer pipeline connection.
It further, further include a return line and the nitrogen recycling bottle being connected with the return line, the nitrogen
Gas returnable bottle is equipped with a return-air escape pipe, the inlet of the other end and heating and temperature controlling device of the return-air escape pipe
The connection of rewarming gas transfer pipeline, nitrogen recycling bottle are equipped with safety relief valve and pressure sensor.
Further, the air shooter road is equipped with several controlled valves；Level sensing is equipped in the liquid nitrogen container
Device.
Further, the frozen gas transfer pipeline and rewarming gas transfer pipeline are separately connected 1~8 group of freezing and answer
Wet body branch, each frozen gas branch and a rewarming gas branch synthesize a gas passage and connect a work spy
Needle.
Further, the cooling coil exit is equipped with temperature sensor.
Further, further include controller, the controller respectively with the heating and temperature controlling device, temperature sensor, liquid
Level sensor is connected with pressure sensor.
Further, the controller be computer, control cooling coil inlet enter pressure limit be 0.1MPa~
The low temperature nitrogen of 40MPa, the low temperature nitrogen that cooling coil exit output temperature range is -40~-196 DEG C.
Further, the work probe includes freezing cutter hub, the freezing cutter hub includes internal be cavity knife shell and
The air inlet pipe being set in knife shell cavity, is equipped with a partition inside the knife shell at point of a knife, and the partition is by the freezing
Cutter hub is divided into non-target area and target area two parts, and the air inlet pipe passes through the partition and extends to freezing cutter hub target area, the partition
It is equipped with several ventholes.
Further, the air inlet pipe is the air inlet pipe or common air inlet pipe that distal end offers Joule-Thomson notch；
The partition is moveable bulkhead.
Further, the cutter hub is equipped with thermometric galvanic couple.
The advantages and positive effects of the present invention are:
Due to the adoption of the above technical scheme, low temperature nitrogen Cryoablation system of the invention has the advantage that
(1) this system inside liquid nitrogen supply equipment by adding evaporator, temperature sensor and pressure sensor, to setting
Standby interior liquid nitrogen carries out heating pressurized treatments and guarantees that the cryogenic media being delivered at work probe is that nitrogen or gas-liquid mixed vapour is subcooled,
Efficiently solve the problems, such as that the gas of liquid nitrogen system is stifled while having reached refrigerating effect；
(2) transfer pipeline of this system includes the frozen gas transfer pipeline and rewarming gas transfer pipeline of homologous setting,
And heating and temperature controlling device is equipped on rewarming gas piping, it can be under the premise of being changed without gas source by adjusting the heated for controlling temperature
Device realizes the rapid rewarming in freezing region；
(3) it is additionally provided with gas gathering mask and cooling coil in the liquid nitrogen container of this system, it can be certainly cooling through coil pipe by frozen gas
It is more preferable to be passed through cooling gas transfer pipeline cooling effect again afterwards；
(4) return-air of this system is again introduced into probe interior after return line and heating and temperature controlling device after collecting,
It directly heats faster heat up under identical heating power compared to cold source gas and achievees the purpose that subtract freezing region rewarming
Small energy consumption has the advantages that energy conservation and environmental protection.
Detailed description of the invention
Fig. 1 is a kind of internal structure connection figure of embodiment of low temperature nitrogen Cryoablation system of the invention；
Fig. 2 is the internal structure connection figure of low temperature nitrogen Cryoablation system another kind embodiment of the invention；
Fig. 3 is the structural schematic diagram of a kind of embodiment of Fig. 1 of the present invention and freezing cutter hub A shown in Fig. 2；
Fig. 4 is the cross-sectional view in the present invention section C-C shown in Fig. 3；
Fig. 5 is the structural schematic diagram of another embodiment of Fig. 1 of the present invention and freezing cutter hub A shown in Fig. 2.
Description of symbols:
1- controller；2- liquid nitrogen container；3- nitrogen recycling bottle；4- return-air escape pipe；5- heating and temperature controlling device；6- liquid nitrogen vaporization
Device；7- rewarming gas transfer pipeline；8- frozen gas transfer pipeline；9- return line；10- work probe；11- cooling coil；
12- gas gathering mask；101- air inlet pipe；102- knife shell；103- thermal insulation layer；104- partition；105- pull rod；106- slider；1021- long
Hole；1041- venthole.
Specific embodiment
Below and specific embodiment the invention will be further described.
Embodiment 1
A kind of low temperature nitrogen Cryoablation system, as shown in Figure 1, including sequentially connected liquid nitrogen container 2, gas transfer pipeline
With work probe 10, the gas transfer pipeline includes frozen gas transfer pipeline 8 and rewarming gas transfer pipeline 7, wherein cold
Freeze at the air inlet of gas transfer pipeline 8 and rewarming gas transfer pipeline 7 and is connected to by a supervisor with liquid nitrogen container；The liquid nitrogen
Liquid nitrogen evaporator 6 is equipped in tank 2, liquid nitrogen container 2 is equipped with pressure sensor P2, safety relief valve a2 and temperature sensor T1, institute
Rewarming gas transfer pipeline 7 is stated equipped with heating and temperature controlling device 5.
Above system further includes a return line 9 and the nitrogen recycling bottle 3 that is connected with the return line 9, nitrogen
Returnable bottle 3 is equipped with a return-air escape pipe 4, the inlet of the other end of the return-air escape pipe 4 and the heating and temperature controlling device 5
Rewarming gas transfer pipeline 7 be connected to, nitrogen recycling bottle 3 be equipped with safety relief valve a2 and pressure controller P1.
The frozen gas transfer pipeline 8 (pipeline is equipped with switch valve c1) and rewarming gas transfer pipeline 7 (are set on pipeline
Have switch valve b1) distal end be respectively classified into 4 freezings and rewarming gas branch (81 and 71, and each road is respectively equipped with out
Close valve c10~c13 and b10~b13), a frozen gas branch 81 and a rewarming gas branch 71 are logical as one group of gas
Road connects a work probe 10.
Liquid level sensor L1 is equipped in liquid nitrogen container, above system further includes controller 1 (preferably computer), the control
Device is connect with the heating and temperature controlling device, temperature sensor, liquid level sensor and pressure sensor respectively, and control cooling coil enters
The low temperature nitrogen pressure that mouthful place's pressure limit is 0.1MPa~40MPa, cooling coil exit output temperature range for -80~-
150 DEG C of low temperature nitrogen；Controller 1 also controls the switch of all switch valves on pipeline in whole system simultaneously.
Work probe 10 in the present embodiment includes freezing cutter hub, and as shown in Figures 3 and 4, the freezing cutter hub includes inside
Knife shell 102 (knife shell inner wall be equipped with thermal insulation layer 103) for cavity and the air inlet pipe 101 that is set in knife shell cavity, the knife shell
Internal that a partition 104 is equipped at point of a knife, the partition 104 is tightly connected with 102 inner wall of knife shell, by the freezing cutter hub point
At non-target area and target area two parts, the air inlet pipe 101 passes through the partition and extends to freezing cutter hub target area, sets on the partition
There are several ventholes 1041.Wherein the air inlet pipe in the present embodiment is common liquid nitrogen frozen air inlet pipe, while being set on cutter hub
There is thermometric galvanic couple.
The course of work of system is as follows in the present embodiment:
Liquid nitrogen is naturally heated or controls liquid nitrogen container using controller after the liquid nitrogen evaporator heating evaporation in liquid nitrogen container
On pressure sensor pressurization become high pressure (pressure limit be 0.1MPa~40MPa) supercooling nitrogen, keep other gases to convey
Valve c1 branch road valve relevant with work probe is opened while valve on pipeline is in off state (in c10~c13
At least one) make nitrogen is subcooled and is delivered at work probe through gas transfer pipeline target area is freezed, the gas after freezing
Body cooled via return air pipeline arrival nitrogen recycling bottle is spare, and valve c1 and work on frozen gas transfer pipeline are closed after freezing
The relevant branch road valve of probe (at least one of c10~c13), the valve b1 and work for opening rewarming gas transfer pipeline are visited
The relevant branch road valve of needle (at least one of b10~b13) is by the heated temperature regulating device of recycling nitrogen in nitrogen recycling tank
The hot nitrogen obtained after heating reaches work probe and carries out rewarming operation to target area, after completion one " freezing-rewarming operation " again
It repeats the above process until reaching refrigerating effect.May be used also when the recycling nitrogen in system operation procedure is unable to satisfy and requires
It is used with carrying out heating rewarming using the cold nitrogen in liquid nitrogen container by the mode of operation for closing b1 valve opening b2 valve.It grasps simultaneously
During work, liquid nitrogen container can also be controlled according to coefficient adjustment the pressure relief valve a2 and a1 of pressure gauge by controller and nitrogen returns
Air pressure in closed cans keeps the safety of above system.
Embodiment 2
A kind of low temperature nitrogen Cryoablation system, as shown in Fig. 2, including sequentially connected liquid nitrogen container 2, gas transfer pipeline
With work probe 10, the gas transfer pipeline includes frozen gas transfer pipeline 8 and rewarming gas transfer pipeline 7, the liquid
Liquid nitrogen evaporator 6 is equipped in nitrogen tank 2, liquid nitrogen container 2 is equipped with pressure sensor, safety relief valve and temperature sensor, described multiple
Warm gas transfer pipeline is equipped with heating and temperature controlling device.
Unlike the first embodiment, gas gathering mask 12 and entrance are additionally provided in the liquid nitrogen container 2 to be connected to the gas gathering mask 12
Cooling coil 11, the outlet of the cooling coil 11 is connected to the frozen gas transfer pipeline 8；The gas gathering mask 12 also with
The rewarming gas transfer pipeline 7 is connected to.The cooling coil exit be equipped with temperature sensor, the temperature sensor also with
Controller connection, for guaranteeing that cooling coil exit output temperature range is -80~-150 DEG C of low temperature nitrogen.
In addition to this, the work probe 10 in the present embodiment includes freezing cutter hub, as shown in figure 5, the frozen knife
It is cavity knife shell 102 (knife shell is preferably to be insulated knife shell) and the air inlet pipe 101 that is set in knife shell cavity that body, which includes internal,.Knife
Shell proximal end shell is equipped with a long hole 1021 extended along knife shell length direction, and being equipped with one at point of a knife inside the knife shell can
Mobile dividing plate 104, the freezing cutter hub is divided into non-target area and target area two parts by partition, and the side of partition 104 is drawn by one
Bar 105 and the slider 106 for being fixed on the pull rod other end are fixed on the long hole of knife shell.The air inlet pipe 101 passes through the partition
Freezing cutter hub target area is extended to, the partition is equipped with several ventholes 1041.Wherein the air inlet pipe in the present embodiment is remote
End offers the air inlet pipe of Joule-Thomson notch, while cutter hub is equipped with thermometric galvanic couple.Partition in the present embodiment can lead to
It crosses adjustment slider 106 to slide to adjust the target area of work probe and the action length of non-target area in knife shell 102, realize
It is variable to freeze ice hockey length, to adapt to different freezing requirements.
The course of work of this system is as follows:
Liquid nitrogen is naturally heated or controls liquid nitrogen container using controller after the liquid nitrogen evaporator heating evaporation in liquid nitrogen container
On pressure sensor pressurization become high pressure (pressure limit be 0.1MPa~40MPa) supercooling nitrogen, keep other gases to convey
Valve c1 branch road valve relevant with work probe is opened while valve on pipeline is in off state (in c10~c13
At least one) to be subcooled nitrogen through the cooling coil pre-cooling being immersed in liquid nitrogen container liquid nitrogen be temperature range be -40~-
Then 196 DEG C of low temperature nitrogen is delivered at work probe using gas transfer pipeline and freezes to target area, after freezing
Gas cooled via return air pipeline arrival nitrogen recycling bottle is spare, and valve c1 and work on frozen gas transfer pipeline are closed after freezing
Make the relevant branch road valve of probe (at least one of c10~c13), opens valve b1 and the work of rewarming gas transfer pipeline
The relevant branch road valve of probe (at least one of b10~b13) fills the heated temperature control of recycling nitrogen in nitrogen recycling tank
It sets the hot nitrogen obtained after heating and reaches work probe to target area progress rewarming operation, after completing one " freezing-rewarming operation "
The above process is repeated until reaching refrigerating effect.When the recycling nitrogen in system operation procedure, which is unable to satisfy, to be required also
Heating rewarming use can be carried out using the cold nitrogen in liquid nitrogen container by closing the mode of operation of b1 valve opening b2 valve.Simultaneously
In operating process, liquid nitrogen container and nitrogen can also be controlled according to coefficient adjustment the pressure relief valve a2 and a1 of pressure gauge by controller
Air pressure in recycling can keeps the safety of above system.
The low temperature nitrogen refrigeration system in the present invention applies also for other gasifiable cryogenic liquids, such as liquid argon, liquid
Helium or liquid oxygen.
Above embodiments describe the invention in detail, but content is only the preferred embodiment of the present invention, no
It can be believed to be used to limit the scope of the invention.Any changes and modifications in accordance with the scope of the present application,
It should still fall within the scope of the patent of the present invention.
Claims (10)
1. a kind of low temperature nitrogen Cryoablation system, including sequentially connected liquid nitrogen container, gas transfer pipeline and work probe, institute
Stating gas transfer pipeline includes frozen gas transfer pipeline and rewarming gas transfer pipeline, it is characterised in that: in the liquid nitrogen container
Equipped with liquid nitrogen evaporator, liquid nitrogen container is equipped with safety relief valve, pressure sensor and temperature sensor, the rewarming gas conveying
Pipeline is equipped with heating and temperature controlling device.
2. low temperature nitrogen Cryoablation system according to claim 1, it is characterised in that: be additionally provided with collection in the liquid nitrogen container
The cooling coil that gas hood and entrance are connected to the gas gathering mask, the outlet of the cooling coil and the frozen gas transfer pipeline
Connection；The gas gathering mask is also connected to the rewarming gas transfer pipeline.
3. low temperature nitrogen Cryoablation system according to claim 1 or 2, it is characterised in that: further include a return line
And the nitrogen recycling bottle being connected with the return line, the nitrogen recycling bottle be equipped with a return-air escape pipe, described time
The other end of gas escape pipe is connected to the rewarming gas transfer pipeline of the inlet of the heating and temperature controlling device, on nitrogen recycling bottle
Equipped with safety relief valve and pressure sensor.
4. low temperature nitrogen Cryoablation system according to claim 1, it is characterised in that: the air shooter road is set
There are several controlled valves；Liquid level sensor is equipped in the liquid nitrogen container.
5. low temperature nitrogen Cryoablation system according to claim 1 or 2, it is characterised in that: the frozen gas conveying
Pipeline and rewarming gas transfer pipeline are separately connected 1~8 group of freezing and rewarming gas branch, each frozen gas branch and one
Rewarming gas branch synthesizes a gas passage and connects a work probe.
6. low temperature nitrogen Cryoablation system according to claim 2, it is characterised in that: the cooling coil exit is set
There is temperature sensor.
7. low temperature nitrogen Cryoablation system according to claim 6, it is characterised in that: it further include controller, the control
Device processed is connect with the heating and temperature controlling device, temperature sensor, liquid level sensor and pressure sensor respectively.
8. low temperature nitrogen Cryoablation system according to claim 6, it is characterised in that: the controller is computer,
Control cooling coil inlet enters the low temperature nitrogen that pressure limit is 0.1MPa~40MPa, cooling coil exit output temperature
Spend the low temperature nitrogen that range is -40~-196 DEG C.
9. low temperature nitrogen Cryoablation system according to claim 1, it is characterised in that: the work probe includes freezing
Cutter hub, the freezing cutter hub include the internal air inlet pipe for being the knife shell of cavity and being set in knife shell cavity, inside the knife shell
A partition is equipped at point of a knife, the freezing cutter hub is divided into non-target area and target area two parts, the air inlet pipe by the partition
Freezing cutter hub target area is extended to across the partition, the partition is equipped with several ventholes.
10. low temperature nitrogen Cryoablation system according to claim 9, it is characterised in that: the air inlet pipe is that distal end is opened
Air inlet pipe or common air inlet pipe equipped with Joule-Thomson notch；The partition is moveable bulkhead, and freeze space may be implemented
Length of field variable adjustment.
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| CN201811653532.XA CN109481003A (en) | 2018-12-29 | 2018-12-29 | A kind of low temperature nitrogen Cryoablation system |
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| CN201811653532.XA CN109481003A (en) | 2018-12-29 | 2018-12-29 | A kind of low temperature nitrogen Cryoablation system |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111058008A (en) * | 2020-01-16 | 2020-04-24 | 浙江工业大学 | Portable sample platform device of temperature rise or fall based on liquid nitrogen refrigeration |
| CN111678930A (en) * | 2020-07-23 | 2020-09-18 | 丹东通达科技有限公司 | Detection device for measuring sample characteristics at low temperature by X-ray diffractometer |
| CN112022326A (en) * | 2020-08-18 | 2020-12-04 | 上海市第十人民医院 | Spray freezing pipe with adjustable scope of action |
| WO2021027397A1 (en) * | 2019-08-13 | 2021-02-18 | 上海导向医疗系统有限公司 | Adjustable cryoablation needle |
| CN113749753A (en) * | 2021-11-09 | 2021-12-07 | 海杰亚（北京）医疗器械有限公司 | Pressure adjusting method and device and cryosurgery system |
| CN114526444A (en) * | 2021-06-30 | 2022-05-24 | 杭州堃博生物科技有限公司 | Rewarming control method based on cryoablation system |
| CN114668481A (en) * | 2022-05-26 | 2022-06-28 | 上海导向医疗系统有限公司 | Dual-system cryotherapy system based on precooling of cryogenic refrigerator |
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