CN105816681A - Traditional Chinese medicine composition for treating qi and yin deficiency type IgA nephropathy - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating qi and yin deficiency type IgA nephropathy .The traditional Chinese medicine composition is characterized by being prepared from, by weight, 10 parts of acanthopanax obovatus hoo, 20 parts of stems of bengal hiptage, 15 parts of roots of intermediate peashrub., 15 parts of balanophora laxiflora hemsl., 15 parts of silene conoidea, 10 parts of pseudostellaria maximowicziana (Franch.et Sav.)Pax ex Pax et Hoffm.[Krascheninikowia maximowicziana.], 20 parts of all-grass of purple cyathocline, 10 parts of pink reineckea herbs, 20 parts of cerastium viscosum L., 15 parts of all-grass of capitatestigma willowweed, 20 parts of dendrobium densiflorum Lindl ex Wall, 25 parts of stems or leaves of fortune euonymus, 9 parts of schisandra clarkevar henryi .yun-nanensis A.C.Smith, 20 parts of twig and leaves of Tibet lyonia and 8 parts of radix glycyrrhizae .The traditional Chinese medicine composition is used for treating qi and yin deficiency type IgA nephropathy and is high in efficiency, reliable in curative effect and free of relapse after healing.

Description

A kind of Chinese medicine composition treating type of deficiency of both QI and YIN IgA nephropathy

Technical field

The present invention relates to a kind of Chinese medicine, a kind of Chinese medicine composition for treating type of deficiency of both QI and YIN IgA nephropathy.

Background technology

IgA nephropathy is most commonly seen a kind of primary glomerulopathy, refers to that glomerular mesangium district is deposited as with IgA or IgA main, companion or the primary glomerular disease deposited without other immunoglobulins in glomerular mesangium district.Categories such as " hematuria " " asthenia " it is attributable in Chinese medicine.The main cause causing morbidity have following some: 1., affection due to external wind and heat, in attacking outside wind heat, heat stores kidney and bladder, and channels is impaired, the absurd row of nutrient blood, and escape of blood from meridians is excessive for hematuria.2., ferritic deficiency of kidney yin, yin asthenia generating intrinsic heat, or tired excessively, damage temper, gas lose have under one's command, blood is hematuria without returning.3., bother excessively, consume sad the moon, hyperactivity of heart-fire, move hot small intestinal, the absurd row of forcing blood and hematuria.Albuminuria is main person, many because of caused by " letting out under vital essence ".Vital essence is preferably hidden and should not be let out, spleen main system report the lucid yang sending up, and if kidney governing storage, spleen not consolidating semen, not the lucid yang sending up, kidney not store essential substances, can make to let out under vital essence and see albumen.Congenital defect, natural endowment is weak, adjusts benefit the most in time, or ferritic is weak, easily suffer from disease, and body void is not multiple after being ill, causes spleen kidney two and loses.4., bothering excessively, body and the spirit crosses consumption, or intemperance of taking food, or the intestines and stomach is damp and hot stagnant, hungry full uncomfortable, impairing the spleen and stomach.Additionally, diseases caused by exogenous pathogenic factor six climate exopathogens, delaying mistake and control, pathogen is controlled for a long time, and positive QI consumed is hindered, and also may result in and lets out under vital essence.Its clinical manifestation is repeated relapsing gross hematuria or microscopic hematuria, can be with albuminuria in various degree, and severe hypertension or renal insufficiency can occur in some patients.At present, the main method for the treatment of IgA nephropathy has Chinese traditional treatment, western medical treatment etc., western medical treatment main purpose to be renal function protecting, and slow down disease progression.And Chinese traditional treatment IgA nephropathy is mainly nursed one's health by entirety, improve the body constitution of patient, control risk factor, fundamentally treat this disease.The IgA nephropathy that the traditional Chinese medical science causes according to different reasons, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: anemopyretic, damp-heat type, type of deficiency of both QI and YIN, type of YIN-deficiency and interior-heat, spleen kidney qi deficiency.At present, the Chinese medicine for the treatment of IgA nephropathy has multiple, but the Chinese patent medicine being directed to type of deficiency of both QI and YIN IgA nephropathy is actually rare, but also there is the defects such as prognosis is poor.

Summary of the invention

The purpose of the present invention aims to provide a kind of Chinese medicine composition treating type of deficiency of both QI and YIN IgA nephropathy, by selecting suitable medical material and proportioning thereof, reaches safely and effectively to cure the purpose of type of deficiency of both QI and YIN IgA nephropathy.

For reaching above-mentioned purpose, the present invention by the following technical solutions: a kind of Chinese medicine composition treating type of deficiency of both QI and YIN IgA nephropathy, it is characterized in that being made up of the medical material of following weight proportion:

Acanthopanax obouatus Hoo 10 parts, Caulis Hiptages benghalensis 20 parts, Radix Caraganae intermediae 15 parts, Balanophora dioica R Br ex Royle 15 parts, Herba Silenes conoideae 15 parts, stick grass 10 parts, Herba Cyathoclines purpureae 20 parts, Herba Reineckeae Carneae 10 parts, Herba Cerastii glomerati 20 parts, Herba Epilobii 15 parts, Dendrobium densiflorum lindl. 20 parts, Caulis Seu Folium Euonymi Fortunei 25 parts, hang fruit 9 parts, wood 20 parts, 8 parts of Radix Glycyrrhizae.

Source and the function of medical material involved in formula cure mainly as follows:

Acanthopanax obouatus Hoo [source] medical material Ji Yuan: for root or the stem of Araliaceae Acanthopanax obouatus Hoo.[nature and flavor] sweet in the mouth；Micro-hardship；[function cures mainly] warm in nature invigorating the spleen and benefiting QI；Kidney calming；Relaxing muscles and tendons and activating QI and blood in the collateral.Main body void is weak；Inappetence；Soreness of the waist and knees；Sexual impotence；Insomnia and dreamful sleep；Forgetful；Anemofrigid-damp arthralgia.

Caulis Hiptages benghalensis [source] medical material Ji Yuan: for the rattan of Malpighiaceae plant Caulis Hiptages benghalensis.[nature and flavor] are puckery；Micro-hardship；[return through] warm in nature kidney channel [function cures mainly] the kidney warming QI invigorating；Arresting seminal emission.Main impotence due to deficiency of the kidney；Seminal emission；Frequent micturition；Spontaneous sweating；Anemofrigid-damp arthralgia.

Radix Caraganae intermediae [source] medical material Ji Yuan: for the root of leguminous plant Caragana intermedia.[nature and flavor] are micro-pungent；Temperature [the return through] heart；Liver Channel [function cures mainly] supplementing QI and nourishing YIN.Main dizziness, cardiopalmus, shortness of breath and fatigue, hypertension.

Balanophora dioica R Br ex Royle [source] medical material Ji Yuan: for the Herb of Balanophoraceae plant flower thinning Balaenoptera borealis Lesson.[nature and flavor] are bitter；[function cures mainly] cool in nature kidney tonifying yin nourishing；Clearing away heat to stop bleeding.Main lumbago due to renal deficiency；Asthenia is hemorrhage；Bleeding hemorrhoids.

Herba Silenes conoideae [source] medical material Ji Yuan: for the herb of pinkwort Herba Silenes conoideae.[nature and flavor] are sweet；Micro-hardship；[return through] cool in nature heart；Liver Channel [function cures mainly] yin nourishing；Heat clearing away；Blood-arresting catamenia-regulating.Main haematemesis；Epistaxis；Chronic consumptive disease is coughed；Spitting of blood；Hematuria；Menoxenia.

Stick grass [source] medical material Ji Yuan: for the dried root of the short and small Radix Ginseng of pinkwort.[nature and flavor] are sweet；Bitter；Tepor [function cures mainly] tonifying the lung；Spleen invigorating；YIN nourishing and the production of body fluid promoting.Main cough due to deficiency of the lung；Insufficiency of the spleen lack of appetite；Cardiopalmus spontaneous perspiration；Tired out weak；Xerostomia.

Herba Cyathoclines purpureae [source] medical material Ji Yuan: for the herb of feverfew cup chrysanthemum.[nature and flavor] bitter in the mouth；[function cures mainly] cool in nature eliminating damp-heat；Resolving toxin and disinhibiting the throat；Cooling blood for hemostasis.Main damp-heat dysentery；Urine leaching pain；Laryngopharynx swelling and pain；Spit blood；Epistaxis.

Herba Reineckeae Carneae [source] medical material Ji Yuan: for the herb of liliaceous plant Herba Reineckeae Carneae.[nature and flavor] are sweet；Cool [function cures mainly] clearing away lung-heat to relieve cough；Cooling blood for hemostasis；Resolving toxin and disinhibiting the throat.Main cough due to lung-heat；Spitting of blood；Spit blood；Epistaxis；Have blood in stool；Laryngopharynx swelling and pain；Cataract；Carbuncle furuncle.

Herba Cerastii glomerati [source] medical material Ji Yuan: for the herb of pinkwort ball sequence grasswort.[nature and flavor] are sweet；Micro-hardship；[return through] cool in nature lung；Stomach；Liver Channel [function cures mainly] heat clearing away；Dampness removing；Removing pathogenic heat from blood and toxic substance from the body.Main cold, fever；Diarrhea due to damp-heat；Discharging fresh blood stool；Acute mastitis；Furuncle；Hypertension.

Herba Epilobii [source] medical material Ji Yuan: for herb [nature and flavor] bitter in the mouth of onagraceae plant Piper pulicatulum C. D C. LIUYECAI；Pungent；Property flat [function cures mainly] wind and heat dispersing；Cooling blood for hemostasis.Main air thermoacoustic is neighed；Pharyngalgia；Edema；Spitting of blood；Have blood in stool；Menorrhagia；Knife injury is hemorrhage.

Dendrobium densiflorum lindl. [source] the orchid family Dendrobium densiflorum lindl. DendrobiumdensiflorumLindlexWall., is used as medicine with stem.[nature and flavor] are sweet, light, micro-salty, cold.[function cures mainly] nourishing YIN for benefiting the kidney, promoting the production of body fluid to quench thirst.Aranea calentura, impairment of body fluid, xerostomia excessive thirst, weak after being ill.

Hang fruit [source] medical material Ji Yuan: for the fruit of Schisandraceae Plant Yunnan Fructus Schisandrae Chinensis.[nature and flavor] acid；Sweet；[function cures mainly] warm in nature astringes the lung stomach invigorating；Kidney tonifying is strong.Main chronic cough；Spontaneous perspiration；Night sweat；Inappetence；Lumbago due to renal deficiency；Neurasthenia.

Caulis Seu Folium Euonymi Fortunei [source] medical material Ji Yuan: for the stem and branch with leaf of Celastraceae plant Caulis Seu Folium Euonymi Fortunei.[nature and flavor] are bitter；Sweet；Micro-pungent；Tepor [return through] liver；Spleen；Kidney channel [function cures mainly] relaxing muscles and tendons and activating QI and blood in the collateral；Kidney tonifying strengthens waist；Hemostasis repercussive.Main soreness of waist and knee joint of suffering from a deficiency of the kidney；Hemiplegia；Rheumatic arthralgia；Infantile convulsion；Spitting of blood；Spit blood；Metrorrhagia；Have through uncomfortable；Uterine prolapse；Injury and bone fracture；Wound hemorrhage.

Wood [source] medical material Ji Yuan: for the branch and leaf of ericad fruitlet basilima sorbifolia.[nature and flavor] sweet in the mouth；[function cures mainly] warm in nature reinforcing spleen and kidney；Invigorate blood circulation strong muscle.Main insufficiency of the spleen diarrhoea；Waist foot is unable；Traumatic injury.

Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.

During the Coryza Treated by Syndrome Differentiation of the traditional Chinese medical science, we can carry out the state of an illness of further patient diagnosed by Renal biospy.The clinical manifestation of type of deficiency of both QI and YIN IgA nephropathy is fatigue and weak, and soreness of waist and knee joint is afraid of cold or feverish sensation in the palms and soles, spontaneous perspiration or night sweat, mouth is thirsty or dry pharynx pain, abdominal distention, inappetence, pale complexion, vexed not relaxing, light red tongue limit has tooth print or enlarged tongue big, white and thin fur or BOHUANG and do, thready and rapid pulse and unable.The present invention uses the proportioning of science, cooperate between each medicine in formula, synergism, made Chinese medicine has the kidney warming QI invigorating, removing toxic substances effect such as removing heat from blood, YIN nourishing and the production of body fluid promoting, can effectively treat type of deficiency of both QI and YIN IgA nephropathy, over 4 years, by showing the use of 100 example patients, effective percentage reaches 100%, and cure rate is 95%, therapeutic effect is good, follows up a case by regular visits to 1 year no longer recur after healing.

Below in conjunction with clinical laboratory data beneficial effects of the present invention is described:

Criterion of therapeutical effect:

Clinical recovery: the clinical symptoms of type of deficiency of both QI and YIN IgA nephropathy, sign disappear or substantially disappear；Effective: the clinical symptoms of type of deficiency of both QI and YIN IgA nephropathy, sign are obviously improved；Effective: the clinical symptoms of type of deficiency of both QI and YIN IgA nephropathy, sign all take a favorable turn；Invalid: the clinical symptoms of type of deficiency of both QI and YIN IgA nephropathy, sign are all not improved or increase the weight of.

Enumerate three model cases below and further illustrate the effect of the present invention:

1, Luo, man, 39 years old, IgA nephropathy patient, recently inappetence, pale complexion, vexed do not relax, spiritlessness and weakness, dizzy limb is weary, and red tongue, tongue are few, while there is tooth to print, thready and rapid pulse and unable.Type of deficiency of both QI and YIN IgA nephropathy it is diagnosed as in here.After taking this prescription 7 days, symptom has been alleviated, and after 14 days, symptom substantially alleviates, and after 21 days, symptom disappears entirely, recovery from illness.

2, Liu, female, 46 years old, IgA nephropathy patient, recently fatigue and weak, soreness of waist and knee joint, be afraid of cold, night sweat, dry pharynx pain, abdominal distention, light red tongue limit has tooth to print, white and thin fur, thready and rapid pulse and unable.Type of deficiency of both QI and YIN IgA nephropathy it is diagnosed as in here.After taking this prescription 7 days, remission, after 14 days, symptom is substantially alleviated, after take the most continuously 7 days, symptom disappears entirely, recovery from illness.

3, what certain, man, 58 years old, IgA nephropathy patient, recently pale complexion, gastral cavilty feeling of fullness, after food more so, feverish sensation in the palms and soles, spontaneous perspiration, but mouth is thirsty, enlarged tongue is big, BOHUANG and do, thready and rapid pulse and unable.Type of deficiency of both QI and YIN IgA nephropathy it is diagnosed as in here.After taking this prescription 14 days, symptom is i.e. basic to disappear, after take again 14 days and carried out after treatment, recovery from illness.

Detailed description of the invention

In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Specific embodiment 1

Weigh Acanthopanax obouatus Hoo 10 grams, Caulis Hiptages benghalensis 20 grams, Radix Caraganae intermediae 15 grams, Balanophora dioica R Br ex Royle 15 grams, Herba Silenes conoideae 15 grams, stick grass 10 grams, Herba Cyathoclines purpureae 20 grams, Herba Reineckeae Carneae 10 grams, Herba Cerastii glomerati 20 grams, Herba Epilobii 15 grams, Dendrobium densiflorum lindl. 20 grams, Caulis Seu Folium Euonymi Fortunei 25 grams, hang fruit 9 grams, wood 20 grams, 8 grams of Radix Glycyrrhizae, add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, concentrates, and is dried, and loads capsule shells, must meet the capsule of 1 day consumption of adult normal.

For treating type of deficiency of both QI and YIN IgA nephropathy.Oral, every bu is taken for early, middle and late three times.

Specific embodiment 2

Weigh Acanthopanax obouatus Hoo 10 grams, Caulis Hiptages benghalensis 20 grams, Radix Caraganae intermediae 15 grams, Balanophora dioica R Br ex Royle 15 grams, Herba Silenes conoideae 15 grams, stick grass 10 grams, Herba Cyathoclines purpureae 20 grams, Herba Reineckeae Carneae 10 grams, Herba Cerastii glomerati 20 grams, Herba Epilobii 15 grams, Dendrobium densiflorum lindl. 20 grams, Caulis Seu Folium Euonymi Fortunei 25 grams, hang fruit 9 grams, wood 20 grams, 8 grams of Radix Glycyrrhizae, add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water, decocts 1.5 hours, filters；Merging filtrate, concentrates, and is dried, and packaging must meet the powder of 1 day consumption of adult normal.

For treating type of deficiency of both QI and YIN IgA nephropathy.Oral, every bu is taken for early, middle and late three times.

Specific embodiment 3

Weigh Acanthopanax obouatus Hoo 10 grams, Caulis Hiptages benghalensis 20 grams, Radix Caraganae intermediae 15 grams, Balanophora dioica R Br ex Royle 15 grams, Herba Silenes conoideae 15 grams, stick grass 10 grams, Herba Cyathoclines purpureae 20 grams, Herba Reineckeae Carneae 10 grams, Herba Cerastii glomerati 20 grams, Herba Epilobii 15 grams, Dendrobium densiflorum lindl. 20 grams, Caulis Seu Folium Euonymi Fortunei 25 grams, hang fruit 9 grams, wood 20 grams, 8 grams of Radix Glycyrrhizae, add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, concentrates, and is dried, and pelletizes according to this area common process, and packaging must meet the granule of 1 day consumption of adult normal.

For treating type of deficiency of both QI and YIN IgA nephropathy.Oral, every bu is taken for early, middle and late three times.

Claims (1)

1. treat a Chinese medicine composition for type of deficiency of both QI and YIN IgA nephropathy, it is characterized in that being made up of the medical material of following weight proportion:

Acanthopanax obouatus Hoo 10 parts, Caulis Hiptages benghalensis 20 parts, Radix Caraganae intermediae 15 parts, Balanophora dioica R Br ex Royle 15 parts, Herba Silenes conoideae 15 parts, stick grass 10 parts, Herba Cyathoclines purpureae 20 parts, Herba Reineckeae Carneae 10 parts, Herba Cerastii glomerati 20 parts, Herba Epilobii 15 parts, Dendrobium densiflorum lindl. 20 parts, Caulis Seu Folium Euonymi Fortunei 25 parts, hang fruit 9 parts, wood 20 parts, 8 parts of Radix Glycyrrhizae.