CN103751545A - Traditional Chinese medicinal preparation for treating IgA nephropathy due to deficiency of both qi and yin - Google Patents
Traditional Chinese medicinal preparation for treating IgA nephropathy due to deficiency of both qi and yin Download PDFInfo
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- CN103751545A CN103751545A CN201410020777.4A CN201410020777A CN103751545A CN 103751545 A CN103751545 A CN 103751545A CN 201410020777 A CN201410020777 A CN 201410020777A CN 103751545 A CN103751545 A CN 103751545A
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- iga nephropathy
- chinese medicine
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- 230000007812 deficiency Effects 0.000 title claims abstract description 22
- 208000010159 IgA glomerulonephritis Diseases 0.000 title claims abstract description 19
- 206010021263 IgA nephropathy Diseases 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 239000003814 drug Substances 0.000 claims abstract description 20
- 241000628997 Flos Species 0.000 claims description 18
- 241000756171 Hypoxis Species 0.000 claims description 9
- 210000000582 semen Anatomy 0.000 claims description 9
- 210000003734 kidney Anatomy 0.000 abstract description 11
- 210000004369 blood Anatomy 0.000 abstract description 8
- 239000008280 blood Substances 0.000 abstract description 8
- 210000004185 liver Anatomy 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 5
- 210000000952 spleen Anatomy 0.000 abstract description 5
- 230000001225 therapeutic effect Effects 0.000 abstract description 5
- 208000006750 hematuria Diseases 0.000 abstract description 3
- 208000011580 syndromic disease Diseases 0.000 abstract description 3
- 206010030113 Oedema Diseases 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 241000214021 Astragalus complanatus Species 0.000 abstract 1
- 241000519459 Cypripedium margaritaceum Species 0.000 abstract 1
- 240000001989 Hypoxis aurea Species 0.000 abstract 1
- 235000002710 Ilex cornuta Nutrition 0.000 abstract 1
- 241001310146 Ilex cornuta Species 0.000 abstract 1
- 241000738645 Limonium aureum Species 0.000 abstract 1
- 241001571723 Lysimachia insignis Species 0.000 abstract 1
- 241000431987 Neocheiropteris fortunei Species 0.000 abstract 1
- 235000002789 Panax ginseng Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 244000161950 Parochetus communis Species 0.000 abstract 1
- 240000002072 Solanum torvum Species 0.000 abstract 1
- 235000013358 Solanum torvum Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 description 9
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000022461 Glomerular disease Diseases 0.000 description 1
- 206010018364 Glomerulonephritis Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010030124 Oedema peripheral Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 231100000852 glomerular disease Toxicity 0.000 description 1
- 210000002601 glomerular mesangium Anatomy 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
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- 208000011117 substance-related disease Diseases 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating IgA nephropathy due to deficiency of both qi and yin. The IgA nephropathy due to deficiency of both qi and yin belongs to the category of hematuria, edema, kidney wind pathogen, deficiency work and so on in Chinese medicine. The IgA nephropathy due to deficiency of both qi and yin belongs to deficiency syndrome, is characterized in deficiency of both spleen and kidney, deficiency of kidney-yin, and water failing to nourish wood, and can cause deficiency of liver-yin. The traditional Chinese medicinal materials with effects of tonifying liver, invigorating qi, invigorating spleen and kidney, and nourishing yin and blood, including Ilex cornuta bark, Parochetus communis, Panax pseudo-ginseng, Hypoxis aurea, Astragalus complanatus, Drynaria fortunei, Cypripedium margaritaceum, Herba Lespedezae, Limonium aureum, Solanum torvum and Lysimachia insignis are decocted in water to obtain decoction. According to clinical trails, the total effective rate is up to 97.9%. Therapeutic results show that the traditional Chinese medicinal preparation disclosed by the invention has distinct therapeutic effect on IgA nephropathy due to deficiency of both qi and yin.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of type of deficiency of both QI and YIN IgA nephropathy.
Background technology
IgA nephropathy refers to that the significant IgA in Yi Zuyi glomerular mesangium district is deposited as the renal glomerular disease of feature, be the most common person in primary glomerulonephritis, and type of deficiency of both QI and YIN IgA nephropathy is a kind of common type in IgA nephropathy.Western medical treatment ubiquity expense is high, and side effect is large, easily produces the situations such as drug dependence, DeGrain.In recent years, Chinese medicine has been obtained important achievement to the treatment of IgA nephropathy, generally adopts the method for TCM Differentiation of Clinical Stages treatment, according to this sick occurrence regularity, and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, not only good effect, and price is low, has no side effect, and is difficult for recurrence.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of type of deficiency of both QI and YIN IgA nephropathy.Type of deficiency of both QI and YIN IgA nephropathy belongs to the categories such as motherland's medical science hematuria, edema, the kidney-wind syndrome, asthenia.Type of deficiency of both QI and YIN IgA nephropathy assertive evidence belongs to deficiency syndrome, and all void of spleen kidney of take is dominant mechanism, damage of kidney-YIN, and the kidney failing to nourish the liver, can cause deficiecny of liver-YIN.Chinese traditional treatment principle is tonifying liver QI invigorating, tonifying speen and tonifying kidney, nourishing YIN and benefiting blood.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment type of deficiency of both QI and YIN IgA nephropathy is made by the Chinese medicine of following weight portion: Cortex Ilicis Cornutae 15-25 part, Flos Caraganae Sinicae 3-9 part, Radix Panacis japonici 9-15 part, Herba hypoxis aureae 15-25 part, Semen Astragali Complanati 10-16 part, Rhizoma Drynariae 9-15 part, Herba Cyperipedii Margaritacei 9-15 part, Herba Lespedezae Cuneatae 15-25 part, Flos Limonii Aurei 2-4 part, Radix Solani Torvi 9-15 part, Radix Lysimachiae Insignis 9-15 part.
Preferably, 20 parts of Cortex Ilicis Cornutaes, 6 parts of Flos Caraganae Sinicaes, 12 parts of Radix Panacis japonicis, 20 parts of Herba hypoxis aureae, 13 parts of Semen Astragali Complanatis, 12 parts of Rhizoma Drynariae, 12 parts of Herba Cyperipedii Margaritaceis, 20 parts of Herba Lespedezae Cuneatae, 3 parts of Flos Limonii Aureis, 12 parts of Radix Solani Torvi, 12 parts of Radix Lysimachiae Insignis.
Preparation method is made decoction by above-mentioned Chinese medicine decocting.
In side: Cortex Ilicis Cornutae nourishing YIN, liver and kidney tonifying; Flos Caraganae Sinicae YIN nourishing and blood, spleen invigorating; Radix Panacis japonici invigorating the spleen and replenishing QI; Herba hypoxis aureae, Semen Astragali Complanati QI invigorating and in, tonifying the kidney to consolidate the essence nourishing the liver to improve visual acuity; Rhizoma Drynariae invigorating kidney, promoting blood circulation, hemostasis; Herba Cyperipedii Margaritacei invigorating the liver and kidney and QI and blood, diuresis; Herba Lespedezae Cuneatae invigorating the liver and kidney, dissipating blood stasis for subsidence of swelling, lung benefiting the moon; Flos Limonii Aurei is enriched blood, pain relieving, antiinflammatory; Radix Solani Torvi promoting blood circulation to remove blood stasis, pain relieving; The circulation of qi promoting of Radix Lysimachiae Insignis dissipating blood stasis, blood-arresting catamenia-regulating.
Clinical data
1, the routine patient of physical data 48 all meets the diagnostic criteria of type of deficiency of both QI and YIN IgA nephropathy.Man's 28 examples, female's 20 examples, 20～52 years old age, average 35.3 years old, the course of disease 6 months～7 years.
2, diagnostic criteria primary symptom: foam urine (pleomorphism erythrocyturia under mirror is accompanied or do not accompanied to urine protein); Inferior disease: the soreness of waist, weak, xerostomia, order are puckery, feverish sensation in the palms and soles, eyelid or back of foot edema, frequent urination at night; Tongue arteries and veins: thready pulse or count accurately, there is indentation on red tongue, thin fur, corpulent tongue or limit.
3, this group of Therapeutic Method patient takes Chinese medicine preparation of the present invention, take Cortex Ilicis Cornutae 20g, Flos Caraganae Sinicae 6g, Radix Panacis japonici 12g, Herba hypoxis aureae 20g, Semen Astragali Complanati 13g, Rhizoma Drynariae 12g, Herba Cyperipedii Margaritacei 12g, Herba Lespedezae Cuneatae 20g, Flos Limonii Aurei 3g, Radix Solani Torvi 12g,
Radix Lysimachiae Insignis 12g.Decocting becomes decoction, and potion, divided and sooner or later took for 2 times every day, 15 days courses for the treatment of, treated continuously 4 courses for the treatment of.
4, criterion of therapeutical effect (1) is alleviated completely: urine protein continues negative, and urine erythrocyte continues to disappear.(2) significantly alleviate: urine protein continuous decrease >=50%, urine erythrocyte continuous decrease >=50%.(3) take a turn for the better: urine protein examination continuous decrease >=25%, urine erythrocyte continuous decrease >=25%.(4) invalid: urine protein or erythrocyte are unchanged or worsen.
5, the routine patient treatment of therapeutic outcome 48 observe the curative effect after 4 courses for the treatment of, wherein alleviates 29 examples (60.4%) completely, significantly alleviates 8 examples (16.7%), 10 examples (20.8%) that take a turn for the better, invalid 1 example (2.1%), total effective rate 97.9%.Therapeutic outcome shows that Chinese medicine preparation of the present invention has significant curative effect aspect treatment type of deficiency of both QI and YIN IgA nephropathy.
The specific embodiment
Embodiment mono-: take Cortex Ilicis Cornutae 20g, Flos Caraganae Sinicae 6g, Radix Panacis japonici 12g, Herba hypoxis aureae 20g, Semen Astragali Complanati 13g, Rhizoma Drynariae 12g, Herba Cyperipedii Margaritacei 12g, Herba Lespedezae Cuneatae 20g, Flos Limonii Aurei 3g, Radix Solani Torvi 12g, Radix Lysimachiae Insignis 12g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment bis-: take Cortex Ilicis Cornutae 25g, Flos Caraganae Sinicae 3g, Radix Panacis japonici 15g, Herba hypoxis aureae 15g, Semen Astragali Complanati 10g, Rhizoma Drynariae 15g, Herba Cyperipedii Margaritacei 9g, Herba Lespedezae Cuneatae 25g, Flos Limonii Aurei 2g, Radix Solani Torvi 15g, Radix Lysimachiae Insignis 9g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment tri-: take Cortex Ilicis Cornutae 15g, Flos Caraganae Sinicae 9g, Radix Panacis japonici 9g, Herba hypoxis aureae 25g, Semen Astragali Complanati 16g, Rhizoma Drynariae 9g, Herba Cyperipedii Margaritacei 15g, Herba Lespedezae Cuneatae 15g, Flos Limonii Aurei 4g, Radix Solani Torvi 9g, Radix Lysimachiae Insignis 15g, above-mentioned Chinese medicine decocting is become to decoction.
Claims (2)
1. treat a Chinese medicine preparation for type of deficiency of both QI and YIN IgA nephropathy, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Cortex Ilicis Cornutae 15-25 part, Flos Caraganae Sinicae 3-9 part, Radix Panacis japonici 9-15 part, Herba hypoxis aureae 15-25 part, Semen Astragali Complanati 10-16 part, Rhizoma Drynariae 9-15 part, Herba Cyperipedii Margaritacei 9-15 part, Herba Lespedezae Cuneatae 15-25 part, Flos Limonii Aurei 2-4 part, Radix Solani Torvi 9-15 part, Radix Lysimachiae Insignis 9-15 part.
2. a kind of Chinese medicine preparation for the treatment of type of deficiency of both QI and YIN IgA nephropathy according to claim 1, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 20 parts of Cortex Ilicis Cornutaes, 6 parts of Flos Caraganae Sinicaes, 12 parts of Radix Panacis japonicis, 20 parts of Herba hypoxis aureae, 13 parts of Semen Astragali Complanatis, 12 parts of Rhizoma Drynariae, 12 parts of Herba Cyperipedii Margaritaceis, 20 parts of Herba Lespedezae Cuneatae, 3 parts of Flos Limonii Aureis, 12 parts of Radix Solani Torvi, 12 parts of Radix Lysimachiae Insignis.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410020777.4A CN103751545B (en) | 2014-01-12 | 2014-01-12 | A kind of Chinese medicine preparation treating type of deficiency of both QI and YIN IgA nephropathy |
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| CN201410020777.4A CN103751545B (en) | 2014-01-12 | 2014-01-12 | A kind of Chinese medicine preparation treating type of deficiency of both QI and YIN IgA nephropathy |
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| CN103751545A true CN103751545A (en) | 2014-04-30 |
| CN103751545B CN103751545B (en) | 2016-06-01 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873718A (en) * | 2015-05-04 | 2015-09-02 | 乜红臻 | Traditional Chinese medicine preparation for treating simple glomerular hematuria of children |
| CN105816729A (en) * | 2016-05-25 | 2016-08-03 | 陈秀宁 | Traditional Chinese medicine composition for treating damp-heat type IgA nephropathy |
| CN105816681A (en) * | 2016-05-25 | 2016-08-03 | 陈秀宁 | Traditional Chinese medicine composition for treating qi and yin deficiency type IgA nephropathy |
| CN105833036A (en) * | 2016-05-27 | 2016-08-10 | 陈秀宁 | Traditional Chinese medicine composition for treating yin deficiency internal heat type IgA kidney disease |
| CN105920453A (en) * | 2016-06-04 | 2016-09-07 | 陈秀宁 | Traditional Chinese medicine composition for treating spleen and kidney qi deficiency IgA nephropathy |
| CN105998771A (en) * | 2016-05-25 | 2016-10-12 | 陈秀宁 | Traditional Chinese medicine composition for treating wind-heat type IgA nephrosis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1278446A (en) * | 1999-06-18 | 2001-01-03 | 贺云青 | Chinese medicinal composition for cerebrovascular disease, rheumatism and rheumatoid disease |
| CN101574440A (en) * | 2008-05-09 | 2009-11-11 | 周庆芹 | Traditional Chinese medicine for treating thrombocytopenic purpura |
-
2014
- 2014-01-12 CN CN201410020777.4A patent/CN103751545B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1278446A (en) * | 1999-06-18 | 2001-01-03 | 贺云青 | Chinese medicinal composition for cerebrovascular disease, rheumatism and rheumatoid disease |
| CN101574440A (en) * | 2008-05-09 | 2009-11-11 | 周庆芹 | Traditional Chinese medicine for treating thrombocytopenic purpura |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873718A (en) * | 2015-05-04 | 2015-09-02 | 乜红臻 | Traditional Chinese medicine preparation for treating simple glomerular hematuria of children |
| CN105816729A (en) * | 2016-05-25 | 2016-08-03 | 陈秀宁 | Traditional Chinese medicine composition for treating damp-heat type IgA nephropathy |
| CN105816681A (en) * | 2016-05-25 | 2016-08-03 | 陈秀宁 | Traditional Chinese medicine composition for treating qi and yin deficiency type IgA nephropathy |
| CN105998771A (en) * | 2016-05-25 | 2016-10-12 | 陈秀宁 | Traditional Chinese medicine composition for treating wind-heat type IgA nephrosis |
| CN105833036A (en) * | 2016-05-27 | 2016-08-10 | 陈秀宁 | Traditional Chinese medicine composition for treating yin deficiency internal heat type IgA kidney disease |
| CN105920453A (en) * | 2016-06-04 | 2016-09-07 | 陈秀宁 | Traditional Chinese medicine composition for treating spleen and kidney qi deficiency IgA nephropathy |
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| CN103751545B (en) | 2016-06-01 |
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Effective date of registration: 20170510 Address after: 226100, No. 588, Jinyang Road, Yue Yue town, Haimen, Jiangsu, Nantong Patentee after: Haimen Yue Yue Textile Co.,Ltd. Address before: 276400 Linyi health center, Yishui, Shandong, China, Yishui Central Hospital, No. 17, Patentee before: Dai Congjun |
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