CN105833036A - Traditional Chinese medicine composition for treating yin deficiency internal heat type IgA kidney disease - Google Patents

Traditional Chinese medicine composition for treating yin deficiency internal heat type IgA kidney disease Download PDF

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CN105833036A
CN105833036A CN201610384178.XA CN201610384178A CN105833036A CN 105833036 A CN105833036 A CN 105833036A CN 201610384178 A CN201610384178 A CN 201610384178A CN 105833036 A CN105833036 A CN 105833036A
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陈秀宁
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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Abstract

The invention discloses a traditional Chinese medicine composition for treating yin deficiency internal heat type IgA kidney disease. The traditional Chinese medicine composition is characterized by comprising, by weight, 20 parts of Herminium monorchis, 15 parts of Geum urbanum L., 30 parts of Crotalaria ferruginea Grah. ex Benth., 15 parts of Salvia roborowskii Maxim., 25 parts of Lithocarpus polystachyus (Wall.) Re-hd., 25 parts of Diplazium donianum (Mett.) Tard-Blot., 15 parts of semen astragali complanati, 25 parts of Chinese holly bark, 60 parts of Potentilla reptans L.var.sericophylla Franch., 15 parts of hypericum sampsonii hance, 8 parts of Canarium bengalense, 15 parts of Polygonum chinense L., 10 parts of ligustrum lucidum ait, 25 parts of Stellaria yunnanensis and 5 parts of radix glycyrrhizae. The traditional Chinese medicine composition for treating the yin deficiency internal heat type IgA kidney disease is high in effective rate, reliable in curative effect and free of relapse after cure.

Description

A kind of Chinese medicine composition treating type of YIN-deficiency and interior-heat IgA nephropathy
Technical field
The present invention relates to a kind of Chinese medicine, a kind of Chinese medicine composition for treating type of YIN-deficiency and interior-heat IgA nephropathy.
Background technology
IgA nephropathy is most commonly seen a kind of primary glomerulopathy, refers to that glomerular mesangium district sinks with IgA or IgA It is main for amassing, companion or the primary glomerular disease deposited in glomerular mesangium district without other immunoglobulins.In Chinese medicine It is attributable to categories such as " hematuria " " asthenia ".The main cause causing morbidity have following some: 1., affection due to external wind and heat, attack outside wind heat into In, heat stores kidney and bladder, and channels is impaired, the absurd row of nutrient blood, and escape of blood from meridians is excessive for hematuria.2., ferritic deficiency of kidney yin, in the deficiency of YIN Heat, or tired excessively, damage temper, gas lose have under one's command, blood is hematuria without returning.3., bother excessively, consume sad the moon, hyperactivity of heart-fire, move Hot small intestinal, the absurd row of forcing blood and hematuria.Albuminuria is main person, many because of caused by " letting out under vital essence ".Vital essence is preferably hidden and should not be let out, spleen main system report The lucid yang sending up, kidney governing storage, if spleen not consolidating semen, not the lucid yang sending up, kidney not store essential substances, can make to let out under vital essence and see albumen.Congenital defect, natural endowment is thin Weak, adjust benefit the most in time, or ferritic is weak, easily suffer from disease, body void is not multiple after being ill, causes spleen kidney two and loses.4., bother excessively, body and the spirit Cross consumption, or intemperance of taking food, or the intestines and stomach is damp and hot stagnant, hungry full uncomfortable, impairing the spleen and stomach.Additionally, diseases caused by exogenous pathogenic factor six climate exopathogens, delay mistake and control, pathogen Bridle for a long time, positive QI consumed is hindered, also be may result in and let out under vital essence.Its clinical manifestation is repeated relapsing gross hematuria or microscopic hematuria, can accompany Having albuminuria in various degree, can there is severe hypertension or renal insufficiency in some patients.At present, IgA nephropathy is treated Main method has Chinese traditional treatment, western medical treatment etc., western medical treatment main purpose to be renal function protecting, and slow down disease progression.In and Cure treatment IgA nephropathy mainly to be nursed one's health by entirety, improve the body constitution of patient, control risk factor, fundamentally treat this disease.In Cure the IgA nephropathy caused according to different reasons, carry out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, primary disease is divided into: be anemopyretic, damp and hot Type, type of deficiency of both QI and YIN, type of YIN-deficiency and interior-heat, spleen kidney qi deficiency.At present, the Chinese medicine for the treatment of IgA nephropathy has multiple, but is directed to the deficiency of YIN The Chinese patent medicine of interior pattern of fever IgA nephropathy is actually rare, but also there is the defects such as prognosis is poor.
Summary of the invention
The purpose of the present invention aims to provide a kind of Chinese medicine composition treating type of YIN-deficiency and interior-heat IgA nephropathy, is closed by selection Suitable medical material and proportioning thereof, reach safely and effectively to cure the purpose of type of YIN-deficiency and interior-heat IgA nephropathy.
For reaching above-mentioned purpose, the present invention by the following technical solutions: a kind of Chinese medicine treating type of YIN-deficiency and interior-heat IgA nephropathy Compositions, is characterized in that being made up of the medical material of following weight proportion:
Musk orchid 20 parts, fragrant 15 parts of bodhi, Canis familiaris L. jingle bell 30 parts, Salvia roborowskii Maxim fruit 15 parts, multiple-ear rock Ke's root 25 parts, comb 25 parts of leaf, Semen Astragali Complanati 15 parts, Cortex Ilicis Cornutae 25 parts, Radix Potentillae sericophyllae 60 parts, Herba Hyperici Sampsonii 15 parts, side olive 8 parts, Radix Polygoni Chinensis 15 parts, Fructus Ligustri Lucidi 10 parts, Radix Stellariae Yunnanensis 25 parts, 5 parts of Radix Glycyrrhizae.
Source and the function of medical material involved in formula cure mainly as follows:
Musk orchid [source] the orchid family Herminium plant musk orchid Herminium monorchis (L.) R.Brown., with Whole herb with root is used as medicine.Autumn excavates, and dries.[nature and flavor] are sweet, temperature.[function cures mainly] enriching yin and nourishing kidney, nourishing the stomach, regulating menstruation.For nerve Weak, dizzy insomnia, irritated thirsty inappetence, early whitening of beard and hair, menoxenia.
Fragrant [source] Rosaceae bodhi perfume (or spice) Geum urbanum L. of bodhi, with all herbal medicine.[nature and flavor] are pungent, sweet, flat.[merit Can cure mainly] enriching yin and nourishing kidney, suppressing the hyperactive liver improving eyesight, reducing swelling and alleviating pain.Cure cold, dizziness headache, hypertension, anemia, chronic enterogastritis, menstruation Uncomfortable, mastitis, the disease such as sore.
The blue Crotalaria ferruginea Grah.ex in Canis familiaris L. jingle bell [source] pulse family bullshit bean plant vacation ground Benth., it is used as medicine with herb or root.Xia Qiu gathers, and cleans chopping, dries or using fresh herb.[nature and flavor] hardship sweet, micro-, flat.[function master Control] nourishing the liver nourishing kidney, relieving cough and asthma, regulating menstruation.For having a dizzy spell caused by deficiency of the liver and kindey, Hiccough and deaf, seminal emission, nephritis, bronchus Inflammation, asthma, menoxenia, leucorrhea.
Salvia roborowskii Maxim fruit [source] medical material Ji Yuan: for the fruit of labiate Salvia roborowskii Maxim.[function cures mainly] grows Kidney tonifying liver;Improving eyesight.Main puerperal asthenia;Hypogalactia;Blurring of vision.
Multiple-ear rock Ke's root [source] medical material Ji Yuan: for the root of Fagaceae multiple ear lithocarpus.[nature and flavor] are sweet;Puckery;Property flat [merit Can cure mainly] invigorating the liver and kidney;Wind-damp dispelling.Main lumbago due to renal deficiency;Rheumatic arthralgia.
Comb leaf [source] medical material Ji Yuan: for the herb of Athyriaceae plant Diplazium donianum (Mett.) Tard. Blet..[nature and flavor] micro-hardship;Cold [function master Control] clearing away heat-damp and promoting diuresis;Removing pathogenic heat from blood and toxic substance from the body.Main jaundice due to damp-heat;Venom;Traumatic hemorrhage;Dysmenorrhea.
Semen Astragali Complanati [source] this product is the dry of leguminous plant astragatus complanatus Astragalus complanatus R.Brown. Dry mature seed.Time of the year when autumn changes into winter fruit maturation taps plant when not yet ftractureing, and dries, and lays seed, removes impurity, dries.[property Taste] sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, improving eyesight.For lumbago due to renal deficiency, seminal emission Premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizziness blurred vision.
Cortex Ilicis Cornutae [source] medical material Ji Yuan: for holly plant Ilex cornuta Lindl. Ilex cornuta Lindl.ex Paxt.'s Bark.[nature and flavor] micro-hardship;Cool [return through] liver;Kidney channel [function cures mainly] invigorating the liver and kidney;Strong waist knee joint.Main deficiency of liver-blood;Kidney foot flaccidity is weak.
Radix Potentillae sericophyllae [source] medical material Ji Yuan: for the tuber of rosaceous plant Potentilla reptans var. sericophylla.[nature and flavor] are sweet;Put down and [return Warp] lung;Spleen;Stomach is through [function cures mainly] YIN nourishing heat extraction, promoting the production of body fluid to quench thirst.Main deficient fever, dyspnea due to deficiency, consumption of body fluid caused by febrile disease, thirsty and dry pharynx, woman Female's foul leukorrhea.
Herba Hyperici Sampsonii [source] medical material Ji Yuan: for the herb of Garcinia maingayii Herba Hyperici Sampsonii.[nature and flavor] are bitter;Pungent;Cold [return through] liver; Spleen channel [function cures mainly] cooling blood for hemostasis;Heat-clearing and toxic substances removing;Promoting blood flow to regulate menstruation;Passive wind and removing obstruction in channels.Main haematemesis;Spitting of blood;Epistaxis;Stranguria with blood;Month Through uncomfortable;Dysmenorrhea;Leucorrhea;Traumatic injury;Rheumatic arthralgia;Lumbago and skelalgia;External also can control tinea capitis;Aphtha;Corneal nebula.
Side olive [source] medical material Ji Yuan: for the fruit of olive subject plant side olive.[nature and flavor] acid;Sweet, puckery;Flat [function cures mainly] Removing heat from the lung and relieving sorethroat;Promoting the production of body fluid to quench thirst.Main pharyngalgia;Cough;Excessive thirst.
Radix Polygoni Chinensis [source] medical material Ji Yuan: the root of charcoal Herba Linderniae Crustaceae of going out for polygonaceae plant.[nature and flavor] are pungent;Sweet;Property flat [function Cure mainly] invigorating spleen and kidney;Pancake liver-yang;Heat-clearing and toxic substances removing;Promoting blood circulation and detumescence.Main body void is weak;Hiccough and deaf;The vertigo;Leucorrhea;Breast Carbuncle;Lung abscess;Traumatic injury.
Fructus Ligustri Lucidi [source] medical material Ji Yuan: for the fruit of Oleaceae plants Fructus Ligustri Lucidi.[nature and flavor] are sweet;Bitter;[return through] cool in nature liver; Kidney channel [function cures mainly] liver and kidney tonifying;Clearind deficient heat;Improving eyesight.Main Light-headedness;Soreness of the waist and knees;Seminal emission;Tinnitus;Early whitening of beard and hair, bone Steam hectic fever;Poor vision.
Radix Stellariae Yunnanensis [source] medical material Ji Yuan: for the root of pinkwort Yunnan Herba stellariae mediae.[nature and flavor] are sweet;Property flat [return through] Liver;Spleen;Kidney channel [function cures mainly] strengthening spleen and nourishing blood;The liver and the kidney tonifying;Detumescence.Main anemia;Spirit is deficient;Dizzy nervous;Tinnitus dim eyesight; Hectic fever;Seminal emission;Menoxenia;Leukorrhagia;Fracture;Mastitis.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..[nature and flavor] are sweet, flat. [return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription. For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion poison Property, strong.
During the Coryza Treated by Syndrome Differentiation of the traditional Chinese medical science, we can carry out the state of an illness of further patient diagnosed by Renal biospy.The deficiency of YIN The clinical manifestation of interior pattern of fever IgA nephropathy is dysphoria with feverish sensation in the chest palms and soles, dry pharynx and pain, the vertigo, tinnitus lumbago, dry mouth with bitter taste, sleep not Rather, night sweat, the most unable, pale complexion, defecate the most dry, red tongue Artemusia lactiflora Wall., thready and rapid pulse or stringy and thready pulse number.The present invention uses joining of science Ratio, cooperates between each medicine in formula, synergism, and made Chinese medicine has temperature compensation Liver and kidney, YIN nourishing heat extraction, promotes the production of body fluid Quench the thirst, the effect such as removing toxic substances, can effectively treat type of YIN-deficiency and interior-heat IgA nephropathy, for many years, by the use of 110 example patients is shown, Effective percentage reaches 100%, and cure rate is 94%, and therapeutic effect is good, follows up a case by regular visits to 1 year no longer recur after healing.
Below in conjunction with clinical laboratory data beneficial effects of the present invention is described:
Criterion of therapeutical effect:
Clinical recovery: the clinical symptoms of type of YIN-deficiency and interior-heat IgA nephropathy, sign disappear or substantially disappear;Effective: yin asthenia generating intrinsic heat The clinical symptoms of type IgA nephropathy, sign are obviously improved;Effective: the clinical symptoms of type of YIN-deficiency and interior-heat IgA nephropathy, sign all have Turn;Invalid: the clinical symptoms of type of YIN-deficiency and interior-heat IgA nephropathy, sign are all not improved or increase the weight of.
Table one: general patient demographic's structure situation
Table two: curative effect situation
Enumerate three model cases below and further illustrate the effect of the present invention:
1, in certain, man, 35 years old, IgA nephropathy patient, dysphoria with feverish sensation in the chest palms and soles, dry pharynx and pain, the vertigo, tinnitus lumbago, complexion is grey In vain, defecate the most dry, red tongue Artemusia lactiflora Wall., stringy and thready pulse number.Type of YIN-deficiency and interior-heat IgA nephropathy it is diagnosed as in here.After taking this prescription 7 days, disease Shape has been alleviated, and after 14 days, symptom substantially alleviates, and after 21 days, symptom disappears entirely, recovery from illness.
2, Huang, female, 52 years old, IgA nephropathy patient, in the heart dysphoria with smothery sensation, think of cold drink, cold drinks and snachs, dizziness, cardiopalmus, the most unable, face Color is pale, red tongue Artemusia lactiflora Wall., stringy and thready pulse number.Type of YIN-deficiency and interior-heat IgA nephropathy it is diagnosed as in here.After taking this prescription 7 days, symptom is delayed Solve, after 14 days, symptom is substantially alleviated, after take the most continuously 7 days, symptom disappears entirely, recovery from illness.
3, Wei, man, 64 years old, IgA nephropathy patient, dizziness and tinnitus, dry mouth with bitter taste, insomnia, night sweat, difficulty and pain in micturition, Red tongue Artemusia lactiflora Wall., thready and rapid pulse.Type of YIN-deficiency and interior-heat IgA nephropathy it is diagnosed as in here.After taking this prescription 14 days, symptom disappears the most substantially Lose, after take again 14 days and carried out after treatment, recovery from illness.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Weigh musk orchid 20 grams, fragrant 15 grams of bodhi, Canis familiaris L. jingle bell 30 grams, Salvia roborowskii Maxim fruit 15 grams, multiple-ear rock Ke's root 25 grams, 25 grams of comb leaf, Semen Astragali Complanati 15 grams, Cortex Ilicis Cornutae 25 grams, Radix Potentillae sericophyllae 60 grams, Herba Hyperici Sampsonii 15 grams, side olive 8 grams, Radix Polygoni Chinensis 15 Gram, Fructus Ligustri Lucidi 10 grams, Radix Stellariae Yunnanensis 25 grams, 5 grams of Radix Glycyrrhizae, add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount Water, decocts 1 hour, filters;Merging filtrate, concentrates, and is dried, and loads capsule shells, must meet the capsule of 1 day consumption of adult normal Agent.
For treating type of YIN-deficiency and interior-heat IgA nephropathy.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Weigh musk orchid 20 grams, fragrant 15 grams of bodhi, Canis familiaris L. jingle bell 30 grams, Salvia roborowskii Maxim fruit 15 grams, multiple-ear rock Ke's root 25 grams, 25 grams of comb leaf, Semen Astragali Complanati 15 grams, Cortex Ilicis Cornutae 25 grams, Radix Potentillae sericophyllae 60 grams, Herba Hyperici Sampsonii 15 grams, side olive 8 grams, Radix Polygoni Chinensis 15 Gram, Fructus Ligustri Lucidi 10 grams, Radix Stellariae Yunnanensis 25 grams, 5 grams of Radix Glycyrrhizae, add 10 times amount water, decoct 2 hours, filter;Filtering residue adds 8 times amount water, Decoct 1.5 hours, filter;Merging filtrate, concentrates, and is dried, and packaging must meet the powder of 1 day consumption of adult normal.
For treating type of YIN-deficiency and interior-heat IgA nephropathy.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Weigh musk orchid 20 grams, fragrant 15 grams of bodhi, Canis familiaris L. jingle bell 30 grams, Salvia roborowskii Maxim fruit 15 grams, multiple-ear rock Ke's root 25 grams, 25 grams of comb leaf, Semen Astragali Complanati 15 grams, Cortex Ilicis Cornutae 25 grams, Radix Potentillae sericophyllae 60 grams, Herba Hyperici Sampsonii 15 grams, side olive 8 grams, Radix Polygoni Chinensis 15 Gram, Fructus Ligustri Lucidi 10 grams, Radix Stellariae Yunnanensis 25 grams, 5 grams of Radix Glycyrrhizae, add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount Water, decocts 1 hour, filters;Merging filtrate, concentrates, and is dried, and pelletizes according to this area common process, packaging, must meet normal The granule of 1 day consumption of adult.
For treating type of YIN-deficiency and interior-heat IgA nephropathy.Oral, every bu is taken for early, middle and late three times.

Claims (1)

1. treat a Chinese medicine composition for type of YIN-deficiency and interior-heat IgA nephropathy, it is characterized in that being made up of the medical material of following weight proportion: Musk orchid 20 parts, fragrant 15 parts of bodhi, Canis familiaris L. jingle bell 30 parts, Salvia roborowskii Maxim fruit 15 parts, multiple-ear rock Ke's root 25 parts, 25 parts of comb leaf, Semen Astragali Complanati 15 parts, Cortex Ilicis Cornutae 25 parts, Radix Potentillae sericophyllae 60 parts, Herba Hyperici Sampsonii 15 parts, side olive 8 parts, Radix Polygoni Chinensis 15 parts, Fructus Ligustri Lucidi 10 Part, Radix Stellariae Yunnanensis 25 parts, 5 parts of Radix Glycyrrhizae.
CN201610384178.XA 2016-05-27 2016-05-27 Traditional Chinese medicine composition for treating yin deficiency internal heat type IgA kidney disease Pending CN105833036A (en)

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Citations (3)

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Publication number Priority date Publication date Assignee Title
CN103751545A (en) * 2014-01-12 2014-04-30 于秀莲 Traditional Chinese medicinal preparation for treating IgA nephropathy due to deficiency of both qi and yin
CN103768404A (en) * 2014-01-09 2014-05-07 肖玉良 Traditional Chinese medicine composition for treating yin-deficiency and interior-heat IgA nephropathy
CN103768201A (en) * 2014-01-09 2014-05-07 刘金荣 Traditional Chinese medicine preparation for treating qi stagnation and blood stasis IgA nephropathy

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768404A (en) * 2014-01-09 2014-05-07 肖玉良 Traditional Chinese medicine composition for treating yin-deficiency and interior-heat IgA nephropathy
CN103768201A (en) * 2014-01-09 2014-05-07 刘金荣 Traditional Chinese medicine preparation for treating qi stagnation and blood stasis IgA nephropathy
CN103751545A (en) * 2014-01-12 2014-04-30 于秀莲 Traditional Chinese medicinal preparation for treating IgA nephropathy due to deficiency of both qi and yin

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Application publication date: 20160810