CN104873718A

CN104873718A - Traditional Chinese medicine preparation for treating simple glomerular hematuria of children

Info

Publication number: CN104873718A
Application number: CN201510237386.2A
Authority: CN
Inventors: 乜红臻
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-05-04
Filing date: 2015-05-04
Publication date: 2015-09-02

Abstract

The invention discloses a traditional Chinese medicine preparation for treating simple glomerular hematuria of children. According to the traditional Chinese medicine, simple hematuria of the children is generally shown as deficient root and excessive superficial; the excess is resulted from deficiency; the excessiveness and deficiency are mixed; people with deficient root are small in immunity; people with excessive superficial suffer from immune complex deposition. According to the traditional Chinese medicine preparation, the traditional Chinese medicines, including eclipta, phoenix hawksbeard root, lespedeza cuneata, uniflower swisscentaury root, thin evodia twig and leaf, caragana sinica rehd, bearded dead nettle root and chinese lizardtail rhizome, are prepared into decoction; the clinical test shows that the traditional Chinese medicine preparation has the effects of strengthening healthy Qi to eliminate pathogens, and treating both symptoms and root causes; the total effective rate is up to 90% and is obviously superior to that of a control group.

Description

A kind of Chinese medicine preparation for the treatment of child's pure glomerular hematuria

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine preparation for the treatment of child's pure glomerular hematuria.

Background technology

Child's pure glomerular hematuria is one of common clinical manifestation of child's urinary system, can occur separately or occur with other symptoms of diseases of urinary system simultaneously, refer to that Source of Hematuria is in glomerule.The primary disease cause of disease is complicated, and histological type is various, and the state of an illness is touching, and easy recurrent exerbation, be a kind of agnogenic syndrome, current doctor trained in Western medicine there is no curative effect therapeutic scheme certainly, and mainly based on symptomatic treatment, prevention and corntrol infects and avoids using infringement renal drug.Through clinical trial for many years, adopt treatment by Chinese herbs renal hematuria not only achieve good curative effect but also safety, effectively, noinvasive, inexpensive.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of child's pure glomerular hematuria.Child's simple hematuria shows as the one side (showing as the deficiency of vital energy, the deficiency of YIN or deficiency of both QI and YIN) of lung spleen kidney deficiency in origin on the one hand on the whole; Wind heat, damp and hot, blood stasis is shown as again on the other hand on mark is real.Pathology has again the difference of heat, void, wet, the stasis of blood.Pure glomerular hematuria is generally deficiency in origin and excess in superficiality, causes reality by void, simulataneous insufficiency and excessive, deficiency in origin person immunologic hypofunction, and marking real person has immune complex deposit, therefore the suitable strengthening vital QI to eliminate pathogenic factors of its Therapeutic Principle, giving consideration to both the incidental and fundamental.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment child pure glomerular hematuria is made up of the Chinese medicine of following weight portion: Herba Ecliptae 6-10 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 5-15 part, Herba Lespedezae Cuneatae 10-20 part, Radix Diurantherae Minoris 6-10 part, Foliumet Ramulus Evodiae 15-25 part, Radix Caraganae Sinicae 15-25 part, Radix Lamii barbati 5-10 part, Rhizoma Saururi 5-10 part.

Preferably, Herba Ecliptae 8 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10 parts, Herba Lespedezae Cuneatae 15 parts, Radix Diurantherae Minoris 8 parts, Foliumet Ramulus Evodiae 20 parts, Radix Caraganae Sinicae 20 parts, Radix Lamii barbati 7 parts, Rhizoma Saururi 7 parts.

Preparation method decocting makes decoction.

Fang Zhong: Herba Ecliptae nourishing the liver and kidney, cooling blood for hemostasis; Crepis crocea Babc.(C.turczaninowii C.A.Mey.) invigorating the liver and kidney, spleen invigorating, to help digestion; Herba Lespedezae Cuneatae invigorating the liver and kidney, dissipating blood stasis for subsidence of swelling, lung benefiting the moon; Radix Diurantherae Minoris heat-clearing and toxic substances removing, dampness removing spleen invigorating; Foliumet Ramulus Evodiae heat-clearing and toxic substances removing, expelling wind and removing dampness, eliminating stasis to stop pain; The lung heat clearing of Radix Caraganae Sinicae strengthening the spleen, blood circulation and channel invigorating; Radix Lamii barbati clearing away heat-damp and promoting diuresis, promoting blood circulation and detumescence; Rhizoma Saururi heat-clearing and toxic substances removing, diuretic dehumidify.

Clinical data

1, physical data 60 example is outpatient service or unit patients, man 28 example, female 32 example; 1 ~ 15 years old age, 8.7 years old mean age; The course of disease 11 examples that are less than 1 month time medical, 1 ~ 3 month 17 example, 4 ~ 6 months 13 examples, 19 examples that are greater than 6 months.Wherein 36 examples are persistence hematuria under mirror, and 25 examples are repeatability microscopic hematuria.10 examples have ictal gross hematuria, and 10 examples have a small amount of albuminuria (< lg/24h), all without hypertension and renal dysfunction, eliminate acute glomerulonephritis and the non-glomerular hematuria of pure simultaneously.The clean fresh erythrocyte phase contrast microscope of urinating of 60 example is observed abnormal rate and is all greater than 80%, and wherein acanthocyte is all greater than 5%.10 routine renal needle biopsy lgAN5 examples, hepatitis B associated glomerulonephritis 4 example, Thin glomerular basement nephropathy 1 example.

2, treatment and care method 60 example are divided into treatment group 30 example at random, matched group 30 example.Matched group: Western medicine vitamin E 50mg, qd; Persantin 1 ~ 2mg/kg, tid; Propylene glycol alginate sodium sulfate 2 ~ 3mg/kg, tid; 654-II0.3 ~ 1mg/kg ivgtt, qd.15 days 1 courses for the treatment of of above medicine, average course for the treatment of 2 months.Treatment group: take Herba Ecliptae 8g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10g, Herba Lespedezae Cuneatae 15g, Radix Diurantherae Minoris 8g, Foliumet Ramulus Evodiae 20g, Radix Caraganae Sinicae 20g, Radix Lamii barbati 7g, Rhizoma Saururi 7g, above prescription every day 1 dose, 15 days 1 courses for the treatment of, average course for the treatment of 2 months.

4, criterion of therapeutical effect recovery from illness: through treatment routine urinalysis continuous 2 weekly checks, check for 2 times weekly RBC be all less than 3/HP, Pro (-), observe more than 1 month without recurring.Take a turn for the better: through the inspection in continuous more than 2 weeks for the treatment of routine urinalysis, RBC comparatively treats front minimizing, former (+) person reduces to 3 ~ 5/HP, former (++) and (++) above person reduces to (+) or >=3/HP, Pro disappearance or unchanged, improvement should continue more than 6 months.Invalid: routine urianlysis is without improvement.

5, therapeutic outcome is through the treatment of 1 ~ 5 course for the treatment of, 6 examples of fully recovering in matched group 30 example (20%), 12 examples that take a turn for the better (40%), invalid 12 examples (40%), total effective rate 60%; 18 examples recovery from illness (60%) in treatment group 30 example, 9 examples that take a turn for the better (30%), invalid 3 examples (10%), total effective rate 90%.P < 0.01 is checked, difference highly significant through Ridit.Matched group can have xerostomia over the course for the treatment of, heating, leukocyte and thrombocytopenia, blood pressure reduce, liver function and electrocardiographic abnormality, headache, cardiopalmus, agitation, the untoward reaction such as weak, drowsiness, adverse reaction rate 15%.Treatment group patient does not have obvious adverse reaction over the course for the treatment of, and patient takes safe and reliable.

Detailed description of the invention

Embodiment one: take Herba Ecliptae 8g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10g, Herba Lespedezae Cuneatae 15g, Radix Diurantherae Minoris 8g, Foliumet Ramulus Evodiae 20g, Radix Caraganae Sinicae 20g, Radix Lamii barbati 7g, Rhizoma Saururi 7g, decocting makes decoction.

Embodiment two: take Herba Ecliptae 10g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 5g, Herba Lespedezae Cuneatae 20g, Radix Diurantherae Minoris 6g, Foliumet Ramulus Evodiae 25g, Radix Caraganae Sinicae 15g, Radix Lamii barbati 10g, Rhizoma Saururi 5g, decocting makes decoction.

Embodiment three: take Herba Ecliptae 6g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 15g, Herba Lespedezae Cuneatae 10g, Radix Diurantherae Minoris 10g, Foliumet Ramulus Evodiae 15g, Radix Caraganae Sinicae 25g, Radix Lamii barbati 5g, Rhizoma Saururi 10g, decocting makes decoction.

Claims

1. treat a Chinese medicine preparation for child's pure glomerular hematuria, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Ecliptae 6-10 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 5-15 part, Herba Lespedezae Cuneatae 10-20 part, Radix Diurantherae Minoris 6-10 part, Foliumet Ramulus Evodiae 15-25 part, Radix Caraganae Sinicae 15-25 part, Radix Lamii barbati 5-10 part, Rhizoma Saururi 5-10 part.

2. a kind of Chinese medicine preparation for the treatment of child's pure glomerular hematuria as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Ecliptae 8 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10 parts, Herba Lespedezae Cuneatae 15 parts, Radix Diurantherae Minoris 8 parts, Foliumet Ramulus Evodiae 20 parts, Radix Caraganae Sinicae 20 parts, Radix Lamii barbati 7 parts, Rhizoma Saururi 7 parts.