CN105816551A - Medicinal film used for treating gynecological diseases and maintaining female external genital organs, and production method thereof - Google Patents

Medicinal film used for treating gynecological diseases and maintaining female external genital organs, and production method thereof Download PDF

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CN105816551A
CN105816551A CN201610132288.7A CN201610132288A CN105816551A CN 105816551 A CN105816551 A CN 105816551A CN 201610132288 A CN201610132288 A CN 201610132288A CN 105816551 A CN105816551 A CN 105816551A
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polyvinyl alcohol
medicine film
mentholum
glycerol
major ingredient
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袁俊杰
高彩霞
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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Abstract

The invention relates to a medicinal film used for treating gynecological diseases and maintaining female external genital organs, and a production method thereof, and belongs to the technical field of multiuse medicines for females. The medicinal film is produced through using fructus cnidii, Hedyotis diffusa, Chinese angelica root, safflower, white peony root, Chinese magnoliavine and apricot kernel as main raw materials and borneol, mentholum, polyvinyl alcohol, glycerol and chlorhexidine acetate as auxiliary materials. The production method has the advantages of simplicity and easy control, and the medicinal film has the advantages of advanced dosage form, convenient and comfortable use, definite therapeutic effect, thorough treatment, no toxic or side effects, no pollution, and organic fusion of treatment of the gynecological diseases and maintenance of the female external genital organs.

Description

A kind of medicine film for gynaecopathia and external genital organs of female maintenance and preparation method
Technical field
The invention belongs to multipurpose women medication technical field, be specifically related to a kind of medicine film for gynaecopathia and external genital organs of female maintenance and preparation method.
Background technology
Along with people's living standard and the raising of spiritual life level, present people increasingly pay attention to quality of life;Especially Contemporary Female; they are while treatment gynaecopathia; support and protection with greater need for carrying out daily moistening in place of this secret of external genitalia official to oneself; they need one to treat urgently and can prophylaxis of gynaecological disorders; and again convenient drug administration, use comfortable gynecological's product; to reach to prevent and cure diseases, moisten the purpose supporting protection external genitalia official.But, on current medical market, this series products almost blank, its present situation is: one, only payes attention to treatment during morbidity, does not focus on the maintenance in daily life.Gynecological's product on medical market, remains in the simple simple bactericidal antiphlogistic stage at present, and using sterilization as unique purpose, seriously ignoring female private part is also one vitals of human body, is also to need daily moistening to support and the reality of protection.Two, toxic and side effects is big.Some medicine contains antibiotic, antibiotics, while killing pathogenic bacterium, also probiotics is inactivated, and then causes intravaginal dysbacteriosis, easily cause Drug pruritus in using;Have is exactly again, and employs the cationic active agents such as benzalkonium bromide (bromogeramine) as germ killing drugs in some product, thus containing certain toxicity;These products can bring certain injury to user, there is the risk jeopardizing health.Three, dosage form single in-convenience in use, uncomfortable.The at present gynecological's product on medical market, whether Chinese medicine, Western medicine, also or Chinese and Western medicine mixture, suppository, tablet, these several dosage forms of pill the most nothing more than, all there is injection volume big, be administered inconvenience, have the drawbacks such as foreign body sensation, easy slippage;During use, often interrupt because of above-mentioned reason, therapeutic process is difficult to reach a certain amount of blood drug level and the drug level of local, thus makes Relapse rate or increase the weight of.
Summary of the invention
Treatment when falling ill only is paid attention to for solving gynecological's product on current medical market, do not focus on the maintenance of female private part in daily life, there is certain toxic and side effects, in-convenience in use, uncomfortable, easily cause the problems such as treatment interruption, and design a kind of lady's treatment gynaecopathia and the medicine for external use film of maintenance external genital organs of female;The present invention uses natural Chinese medicine raw material and environmental protection raw material; the Chinese medicine preparation technique of advanced person in the present age is used to make; its scientific formulation is reasonable, advanced unique; there is antibacterial, antiinflammatory, antipruritic; heat-clearing and toxic substances removing; blood stasis dispersing and deswelling, moistens and supports and protect the effects such as external genital organs of female, make the external system of growing of women be in a healthy ecological environment.
The technical scheme is that a kind of medicine film for gynecopathy therapeutic and external genital organs of female maintenance, it contains the major ingredient of following weight proportioning: Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20% and Semen Armeniacae Amarum 0.8-20%.
The above-mentioned medicine film for gynecopathy therapeutic and external genital organs of female maintenance, is also made up of the adjuvant of following weight proportioning: Borneolum Syntheticum 1-3%, Mentholum 1-3%, polyvinyl alcohol 6.8-20%, glycerol 0.5-5% and chlorhexidine acetate 0.018-0.5%.
Preferably, the weight proportion of medicine film major ingredient is specifically: Fructus Cnidii 40%, Herba Hedyotidis Diffusae 20%, Radix Angelicae Sinensis 10%, Flos Carthami 5%, the Radix Paeoniae Alba 10%, Fructus Schisandrae Chinensis 10%, Semen Armeniacae Amarum 5%.
Preferably, the weight proportion of medicine film adjuvant is specifically: Borneolum Syntheticum 1.5%, Mentholum 1.5%, polyvinyl alcohol 13%, glycerol 1%, chlorhexidine acetate 0.25%.
Preferably, the weight proportion of medicine film major ingredient is specifically: Fructus Cnidii 30%, Herba Hedyotidis Diffusae 15%, Radix Angelicae Sinensis 13%, Flos Carthami 10%, the Radix Paeoniae Alba 15%, Fructus Schisandrae Chinensis 15%, Semen Armeniacae Amarum 2%.
Preferably, the weight proportion of medicine film adjuvant is specifically: Borneolum Syntheticum 2.5%, Mentholum 2%, polyvinyl alcohol 8.5%, glycerol 4%, chlorhexidine acetate 0.25%.
Preferably, the weight proportion of medicine film major ingredient is specifically: Fructus Cnidii 50%, Herba Hedyotidis Diffusae 10%, Radix Angelicae Sinensis 8%, Flos Carthami 7%, the Radix Paeoniae Alba 5%, Fructus Schisandrae Chinensis 5%, Semen Armeniacae Amarum 15%.
Preferably, the weight proportion of medicine film adjuvant is specifically: Borneolum Syntheticum 2%, Mentholum 1%, polyvinyl alcohol 16%, glycerol 2.5%, chlorhexidine acetate 0.3%.
The preparation method of above-mentioned medicine film is: take off the major ingredient stating weight proportion: Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20% and Semen Armeniacae Amarum 0.8-20%;
The medicine film major ingredient of above-mentioned weight proportion is cleaned through screening, extract, filters, concentrates, precipitate with ethanol, decolouring, prepared traditional Chinese medicine liquid;
Taking above-mentioned traditional Chinese medicine liquid, add polyvinyl alcohol, mix homogeneously also heats;In heating process, then it is separately added into Borneolum Syntheticum, Mentholum, glycerol, chlorhexidine acetate, stirs and make molten slurry;By the described molten slurry masking stirred and dry.
Concrete, take the above-mentioned traditional Chinese medicine liquid prepared by medicine film major ingredient, adding polyvinyl alcohol, mix homogeneously also heats, in heating process, it is separately added into Borneolum Syntheticum, Mentholum, glycerol, chlorhexidine acetate again, stir and make molten slurry, by the described molten slurry masking stirred and dry, specifically include following steps: take the described traditional Chinese medicine liquid of 82.75%, adding the polyvinyl alcohol of 13%, mix homogeneously also heats;And, in heating process, then it is separately added into Borneolum Syntheticum 1-3%, Mentholum 1-3%, polyvinyl alcohol 6.8-20%, glycerol 0.5-5% and chlorhexidine acetate 0.018-0.5%, stirs and make molten slurry;By the described molten slurry masking stirred and dry to humidity 20-26%RH.
The invention has the beneficial effects as follows: it is simple that the present invention has production method; it is easily controlled; dosage form is advanced and easy to use, comfortable, determined curative effect, thorough treatment, have no side effect, pollution-free; by treatment gynaecopathia and maintenance external genital organs of female is organic combines together; it is solubilized after running into secretions; release drug effect; play rapidly antibacterial, antiinflammatory, antipruritic, heat-clearing and toxic substances removing, blood stasis dispersing and deswelling; moisten and support and protect the effects such as external genital organs of female, make female external genital organs system be in a healthy ecological environment.Meanwhile, this medicine film, after intravaginal is dissolved, can form thin layer on the vaginal wall, because of without producing the drawback such as seepage, slippage, foreign body sensation, and convenient drug administration, after administration can activity immediately, do not affect work, learn and move.
Accompanying drawing explanation
A kind of medicine membrane preparation method flow chart that Fig. 1 provides for the present embodiment;
The another kind of medicine membrane preparation method flow chart that Fig. 2 provides for the present embodiment.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described.
A kind of lady's treatment gynaecopathia and the medicine for external use film of maintenance external genital organs of female, its concrete composition and manufacture method be: by pharmaceutical formulation and weight proportion, take Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20%, Semen Armeniacae Amarum 0.8-20%, through screening, clean, extract, filter, concentrating, precipitate with ethanol, decolouring, prepare near colorless traditional Chinese medicine liquid;Take traditional Chinese medicine liquid, add polyvinyl alcohol 6.8-20%, mix homogeneously, add thermosol slurry, it is separately added into Borneolum Syntheticum 1-3%, Mentholum 1-3%, glycerol 0.5-5%, chlorhexidine acetate 0.018-0.5% again, masking after stirring, dries to humidity 20-26%, cuts, packs, makes the medicine for external use film of lady's gynaecopathia and maintenance external genital organs of female.
Specifically, the present embodiment provides a kind of medicine film for gynecopathy therapeutic and external genital organs of female maintenance, and described medicine for external use film contains the major ingredient of following weight proportioning: Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20% and Semen Armeniacae Amarum 0.8-20%.
Preferably, the another kind described medicine for external use film provided in the present embodiment contains the major ingredient of following weight proportioning: Fructus Cnidii 25-50%, Herba Hedyotidis Diffusae 8-27%, Radix Angelicae Sinensis 1-15%, Flos Carthami 0.8-12%, Radix Paeoniae Alba 5-20%, Fructus Schisandrae Chinensis 5-20% and Semen Armeniacae Amarum 1-20%.
Preferably, the another kind described medicine for external use film provided in the present embodiment contains the major ingredient of following weight proportioning: Fructus Cnidii 30-45%, Herba Hedyotidis Diffusae 10-25%, Radix Angelicae Sinensis 5-10%, Flos Carthami 3-10%, Radix Paeoniae Alba 5-15%, Fructus Schisandrae Chinensis 5-15% and Semen Armeniacae Amarum 5-15%.
Preferably, the described medicine for external use film provided in the present embodiment is also made up of the adjuvant of following weight proportioning: Borneolum Syntheticum 1-3%, Mentholum 1-3%, polyvinyl alcohol 6.8-20%, glycerol 0.5-5% and chlorhexidine acetate 0.018-0.5%.
A kind of lady's treatment gynaecopathia and the medicine for external use film of maintenance external genital organs of female, its best drug weight proportioning and manufacture method be: takes Fructus Cnidii 40%, Herba Hedyotidis Diffusae 20%, Radix Angelicae Sinensis 10%, Flos Carthami 5%, the Radix Paeoniae Alba 10%, Fructus Schisandrae Chinensis 10%, Semen Armeniacae Amarum 5%, through screening, clean, extract, filter, concentrating, precipitate with ethanol, decolouring, prepare near colorless traditional Chinese medicine liquid;Take traditional Chinese medicine liquid 82.75%, polyvinyl alcohol 13%, mix homogeneously, add thermosol slurry, it is separately added into again: Borneolum Syntheticum 1.5%, Mentholum 1.5%, glycerol 1%, chlorhexidine acetate 0.25%, after stirring, masking, dry to humidity 20-26%, cut, pack, make the medicine for external use film of lady's gynaecopathia and maintenance external genital organs of female.
Preferably, major ingredient weight proportion described in the present embodiment is specifically: Fructus Cnidii 40%, Herba Hedyotidis Diffusae 20%, Radix Angelicae Sinensis 10%, Flos Carthami 5%, the Radix Paeoniae Alba 10%, Fructus Schisandrae Chinensis 10%, Semen Armeniacae Amarum 5%.
The present embodiment takes the traditional Chinese medicine liquid 82.75% being made into by major ingredient, traditional Chinese medicine liquid adds the adjuvant of following weight proportioning.Present embodiment major ingredient proportioning is 82.75%, and major ingredient proportioning can be 50%, 60%, 30%, 20%, 10% or 90% or 95% in other embodiments, and concrete proportioning is not limited by present embodiment.
Preferably, described adjuvant weight proportion is specifically: Borneolum Syntheticum 1.5%, Mentholum 1.5%, polyvinyl alcohol 13%, glycerol 1%, chlorhexidine acetate 0.25%.
Preferably, concrete in another embodiment provide a kind of medicine film, the weight proportion of described major ingredient specifically: Fructus Cnidii 30%, Herba Hedyotidis Diffusae 15%, Radix Angelicae Sinensis 13%, Flos Carthami 10%, the Radix Paeoniae Alba 15%, Fructus Schisandrae Chinensis 15%, Semen Armeniacae Amarum 2%.
The present embodiment takes the traditional Chinese medicine liquid 88% being made into by major ingredient, traditional Chinese medicine liquid adds the adjuvant of following weight proportioning.Present embodiment major ingredient proportioning is 88%, in other embodiments major ingredient proportioning > 0, can be arbitrary value, and concrete proportioning is not limited by present embodiment.
Wherein, the weight proportion of described adjuvant is specifically: Borneolum Syntheticum 2.5%, Mentholum 2%, polyvinyl alcohol 8.5%, glycerol 4%, chlorhexidine acetate 0.25%.
Preferably, concrete in another embodiment provide a kind of medicine film, the weight proportion of described major ingredient specifically: Fructus Cnidii 50%, Herba Hedyotidis Diffusae 10%, Radix Angelicae Sinensis 8%, Flos Carthami 7%, the Radix Paeoniae Alba 5%, Fructus Schisandrae Chinensis 5%, Semen Armeniacae Amarum 15%.
The present embodiment takes the traditional Chinese medicine liquid 60% being made into by major ingredient, traditional Chinese medicine liquid adds the adjuvant of following weight proportioning.Present embodiment major ingredient proportioning is 60%, in other embodiments major ingredient proportioning > 0, can be arbitrary value, and concrete proportioning is not limited by present embodiment.
Wherein, the weight proportion of described adjuvant is specifically: Borneolum Syntheticum 2%, Mentholum 1%, polyvinyl alcohol 16%, glycerol 2.5%, chlorhexidine acetate 0.3%.
Preferably, concrete in another embodiment provide a kind of medicine film, described major ingredient weight proportion specifically: Fructus Cnidii 30%, Herba Hedyotidis Diffusae 15%, Radix Angelicae Sinensis 13%, Flos Carthami 5%, the Radix Paeoniae Alba 10%, Fructus Schisandrae Chinensis 10%, Semen Armeniacae Amarum 5%.
The present embodiment takes the traditional Chinese medicine liquid 25% being made into by major ingredient, traditional Chinese medicine liquid adds the adjuvant of following weight proportioning.Present embodiment major ingredient proportioning is 25%, in other embodiments major ingredient proportioning > 0, can be arbitrary value, and concrete proportioning is not limited by present embodiment.
Wherein, described adjuvant weight proportion is specifically: Borneolum Syntheticum 1.5%, Mentholum 1.5%, polyvinyl alcohol 13%, glycerol 1%, chlorhexidine acetate 0.25%.
Preferably, concrete in another embodiment provide a kind of medicine film, described major ingredient weight proportion specifically: Fructus Cnidii 35%, Herba Hedyotidis Diffusae 20%, Radix Angelicae Sinensis 14%, Flos Carthami 6%, the Radix Paeoniae Alba 18%, Fructus Schisandrae Chinensis 6%, Semen Armeniacae Amarum 1%.
The present embodiment takes the traditional Chinese medicine liquid 15% being made into by major ingredient, traditional Chinese medicine liquid adds the adjuvant of following weight proportioning.Present embodiment major ingredient proportioning is 15%, in other embodiments major ingredient proportioning > 0, can be arbitrary value, and concrete proportioning is not limited by present embodiment.
Wherein, described adjuvant weight proportion is specifically: Borneolum Syntheticum 1.2%, Mentholum 2.5%, polyvinyl alcohol 17%, glycerol 1.5%, chlorhexidine acetate 0.45%.
Preferably, concrete in another embodiment provide a kind of medicine film, described major ingredient weight proportion specifically: Fructus Cnidii 55%, Herba Hedyotidis Diffusae 8%, Radix Angelicae Sinensis 3%, Flos Carthami 9%, the Radix Paeoniae Alba 8%, Fructus Schisandrae Chinensis 13%, Semen Armeniacae Amarum 4%.
The present embodiment takes the traditional Chinese medicine liquid 45% being made into by major ingredient, traditional Chinese medicine liquid adds the adjuvant of following weight proportioning.Present embodiment major ingredient proportioning is 45%, in other embodiments major ingredient proportioning > 0, can be arbitrary value, and concrete proportioning is not limited by present embodiment.
Wherein, described adjuvant weight proportion is specifically: Borneolum Syntheticum 2.6%, Mentholum 2.7%, polyvinyl alcohol 11%, glycerol 3.5%, chlorhexidine acetate 0.35%.
Refer to Fig. 1, a kind of medicine membrane preparation method flow chart that Fig. 1 provides for the present embodiment, as shown in Figure 1, the present embodiment provides a kind of method preparing above-mentioned medicine film, described medicine film contains the major ingredient of following weight proportioning: Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20% and Semen Armeniacae Amarum 0.8-20%, said method comprising the steps of:
S110, the major ingredient of weight proportion in above-mentioned particular range is cleaned through screening, extract, filters, concentrates, precipitate with ethanol, decolouring, prepared traditional Chinese medicine liquid;
S120, taking described traditional Chinese medicine liquid, add polyvinyl alcohol, mix homogeneously also heats;
In S130, heating process, then it is separately added into Borneolum Syntheticum, Mentholum, glycerol, chlorhexidine acetate, stirs and make molten slurry;
S140, by the described molten slurry masking stirred, dry to humidity 20-26RH%.
Preferably, the another kind of medicine membrane preparation method flow chart that Fig. 2, Fig. 2 provide is referred to for the present embodiment, based on the medicine membrane preparation method shown in Fig. 1, as in figure 2 it is shown, in described step S120, i.e. take described traditional Chinese medicine liquid, adding polyvinyl alcohol, mix homogeneously also heats, and specifically includes following steps:
S121, take 82.75% described traditional Chinese medicine liquid, add 13% polyvinyl alcohol, mix homogeneously also heats;And, and in step S130, i.e. in heating process, then it is separately added into Borneolum Syntheticum, Mentholum, glycerol, chlorhexidine acetate, stirs and make molten slurry, specifically include following steps:
In S131, heating process, then it is separately added into Borneolum Syntheticum 1-3%, Mentholum 1-3%, polyvinyl alcohol 6.8-20%, glycerol 0.5-5% and chlorhexidine acetate 0.018-0.5%, stirs and make molten slurry.
The invention belongs to externally-applied female many effects medicine; it is positioned over during use in vagina; this medicine film puts into intravaginal; it is solubilized after running into secretions; release drug effect; play rapidly antibacterial, antiinflammatory, antipruritic, heat-clearing and toxic substances removing, blood stasis dispersing and deswelling, moisten and support and the effect such as protection external genital organs of female, make female external genital organs system be in a healthy ecological environment.Meanwhile, this medicine film, after intravaginal is dissolved, can form thin layer on the vaginal wall, because of without producing the drawback such as seepage, slippage, foreign body sensation, and convenient drug administration, after administration can activity immediately, do not affect work, learn and move.

Claims (10)

1. one kind is used for gynaecopathia and the medicine film of external genital organs of female maintenance, it is characterized in that, described medicine film contains the major ingredient of following weight proportioning: Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20% and Semen Armeniacae Amarum 0.8-20%.
Medicine film the most according to claim 1, it is characterised in that described medicine film is also made up of the adjuvant of following weight proportioning: Borneolum Syntheticum 1-3%, Mentholum 1-3%, polyvinyl alcohol 6.8-20%, glycerol 0.5-5% and chlorhexidine acetate 0.018-0.5%.
Medicine film the most according to claim 2, it is characterised in that the weight proportion of described major ingredient specifically: Fructus Cnidii 40%, Herba Hedyotidis Diffusae 20%, Radix Angelicae Sinensis 10%, Flos Carthami 5%, the Radix Paeoniae Alba 10%, Fructus Schisandrae Chinensis 10%, Semen Armeniacae Amarum 5%.
Medicine film the most according to claim 3, it is characterised in that the weight proportion of described adjuvant specifically: Borneolum Syntheticum 1.5%, Mentholum 1.5%, polyvinyl alcohol 13%, glycerol 1%, chlorhexidine acetate 0.25%.
Medicine film the most according to claim 2, it is characterised in that the weight proportion of described major ingredient specifically: Fructus Cnidii 30%, Herba Hedyotidis Diffusae 15%, Radix Angelicae Sinensis 13%, Flos Carthami 10%, the Radix Paeoniae Alba 15%, Fructus Schisandrae Chinensis 15%, Semen Armeniacae Amarum 2%.
Medicine film the most according to claim 5, it is characterised in that the weight proportion of described adjuvant specifically: Borneolum Syntheticum 2.5%, Mentholum 2%, polyvinyl alcohol 8.5%, glycerol 4%, chlorhexidine acetate 0.25%.
Medicine film the most according to claim 2, it is characterised in that the weight proportion of described major ingredient specifically: Fructus Cnidii 50%, Herba Hedyotidis Diffusae 10%, Radix Angelicae Sinensis 8%, Flos Carthami 7%, the Radix Paeoniae Alba 5%, Fructus Schisandrae Chinensis 5%, Semen Armeniacae Amarum 15%.
Medicine film the most according to claim 7, it is characterised in that the weight proportion of described adjuvant specifically: Borneolum Syntheticum 2%, Mentholum 1%, polyvinyl alcohol 16%, glycerol 2.5%, chlorhexidine acetate 0.3%.
9. the method for the medicine film that a kind is prepared as described in arbitrary in claim 1 to 8, it is characterized in that, described medicine film contains the major ingredient of following weight proportioning: Fructus Cnidii 20-60%, Herba Hedyotidis Diffusae 5-30%, Radix Angelicae Sinensis 0.8-15%, Flos Carthami 1-15%, Radix Paeoniae Alba 1-20%, Fructus Schisandrae Chinensis 1-20% and Semen Armeniacae Amarum 0.8-20%, said method comprising the steps of:
The described major ingredient of above-mentioned weight proportion is cleaned through screening, extract, filters, concentrates, precipitate with ethanol, decolouring, prepared traditional Chinese medicine liquid;
Taking described traditional Chinese medicine liquid, add polyvinyl alcohol, mix homogeneously also heats;In heating process, then it is separately added into Borneolum Syntheticum, Mentholum, glycerol, chlorhexidine acetate, stirs and make molten slurry;By the described molten slurry masking stirred and dry.
10. the method preparing described medicine film as claimed in claim 9, it is characterized in that, described in take described traditional Chinese medicine liquid, add polyvinyl alcohol, mix homogeneously also heats, in heating process, then it is separately added into Borneolum Syntheticum, Mentholum, glycerol, chlorhexidine acetate, stirs and make molten slurry, by the described molten slurry masking stirred and dry, specifically including following steps: take the described traditional Chinese medicine liquid of 82.75%, add the polyvinyl alcohol of 13%, mix homogeneously also heats;And, in heating process, then it is separately added into Borneolum Syntheticum 1-3%, Mentholum 1-3%, polyvinyl alcohol 6.8-20%, glycerol 0.5-5% and chlorhexidine acetate 0.018-0.5%, stirs and make molten slurry;By the described molten slurry masking stirred and dry to humidity 20-26%RH.
CN201610132288.7A 2016-03-09 2016-03-09 Medicinal film used for treating gynecological diseases and maintaining female external genital organs, and production method thereof Pending CN105816551A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106214882A (en) * 2016-08-19 2016-12-14 吉安市御美丽健康产业股份有限公司 A kind of high intensity antibacterial liquid gel and preparation method thereof
CN115429835A (en) * 2022-08-09 2022-12-06 袁俊杰 A medicinal film for treating gynecological diseases and caring female external genitalia and its preparation method

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Publication number Priority date Publication date Assignee Title
CN1686192A (en) * 2005-02-01 2005-10-26 哈尔滨老君堂生物科技有限责任公司 External use medicinal film for treating gynecopathy and preventing accidental pregnancy
CN103007124A (en) * 2012-12-28 2013-04-03 吉林大学公共卫生学院 Chinese medicine preparation for treating gynecologic inflammation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686192A (en) * 2005-02-01 2005-10-26 哈尔滨老君堂生物科技有限责任公司 External use medicinal film for treating gynecopathy and preventing accidental pregnancy
CN103007124A (en) * 2012-12-28 2013-04-03 吉林大学公共卫生学院 Chinese medicine preparation for treating gynecologic inflammation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106214882A (en) * 2016-08-19 2016-12-14 吉安市御美丽健康产业股份有限公司 A kind of high intensity antibacterial liquid gel and preparation method thereof
CN115429835A (en) * 2022-08-09 2022-12-06 袁俊杰 A medicinal film for treating gynecological diseases and caring female external genitalia and its preparation method

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Application publication date: 20160803