CN105816386B - A kind of lipstick and preparation method thereof assisting in the treatment of herpes labialis - Google Patents

A kind of lipstick and preparation method thereof assisting in the treatment of herpes labialis Download PDF

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CN105816386B
CN105816386B CN201610300046.4A CN201610300046A CN105816386B CN 105816386 B CN105816386 B CN 105816386B CN 201610300046 A CN201610300046 A CN 201610300046A CN 105816386 B CN105816386 B CN 105816386B
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parts
lipstick
beeswax
herpes labialis
vaseline
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CN105816386A (en
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吴静澜
张永萍
黄琴
徐剑
陈晓兰
杨芳芳
缪燕艳
吴江顺
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Guizhou Valid Pharmaceutical Co ltd
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Guiyang College of Traditional Chinese Medicine
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a kind of lipstick and preparation method thereof for assisting in the treatment of herpes labialis, the lipstick of the adjuvant treatment herpes labialis is mainly made of honeysuckle, pueraria lobata, Radix Glycyrrhizae, menthol, beeswax, vaseline, Groomwell root oil and lanolin.The lipstick of adjuvant treatment herpes labialis of the present invention can be used for assisting in the treatment of herpes labialis, dry lip harelip, cheilitis;Moisturizing effect is good, and anti-chap effect is good.

Description

A kind of lipstick and preparation method thereof assisting in the treatment of herpes labialis
Technical field
The present invention relates to a kind of lipsticks and preparation method thereof for assisting in the treatment of herpes labialis, belong to the neck of cosmetic art Domain.
Background technique
Herpes labialis is also referred to as herpes facialis, is herpe simplex one of the most common type type.Its cause of disease is infection herpe simplex Virus.Show as dense clusters or several groups of syringe needle size water then occur from the beginning of locally often first having scorching hot, itch and flush Blister, small compared with the blister of essential and compared with gathering, rotten to the corn after rupture, sepage, gradual drying incrustation, whole process pass through about 1~2 In week, rear part can there are temporary pigmentations.Damage is apt to occur in mucocutaneous intersection, as bicker, antelabium and nostril are attached Closely, face, lip person are also betided.It typically occur in fever, infection, flu or solarization wind after, life is nervous, the moon Through period, or when immune system is suppressed.This disease tool is highly infectious.It incubation period about 3-10 days, can after there is herpes labialis It can maintain three weeks as long as.To avoid above-mentioned illness from occurring in lip, it is fabulous choosing that smearing, which has the lip gloss of antivirus action, It selects.
Nowadays, lip-stick has become the indispensable cosmetics of people, especially dry autumn and winter, keeps lip Not dry and cracked almost everyone urgent need is moistened in portion.
Currently, lipstick and lip gloss in the market can only play the role of beautification and profit lip to lip, some lip gloss are not But it not being avoided that herpes of mouth, for a long time using will cause dry and cracked lip, decortication and pigmentation instead, leading to herpes of mouth. Meanwhile the drug for the treatment of or adjuvant treatment herpes of mouth also has very much, these drug slow effect, curative effect be not significant, also there is part Drug can be such that herpes symptom alleviates, but most of patients easily leaves the neuralgia of varying degree after bleb recession.
Summary of the invention
Present invention aims at provide a kind of lipstick and preparation method thereof for assisting in the treatment of herpes labialis.It is of the present invention The lipstick of adjuvant treatment herpes labialis have the function of certain adjuvant treatment herpes labialis, dry lip harelip, cheilitis;It is free of Hormone, it is highly-safe, it has no adverse reaction, and moisturizing effect is good, anti-chap effect is good.
The present invention adopts the following technical scheme that realization: a kind of lipstick assisting in the treatment of herpes labialis calculates by weight, main Will be 60-100 parts by honeysuckle, 40-80 parts of pueraria lobata, 20-60 parts of Radix Glycyrrhizae, 0.3-1.1 parts of menthol, 140-180 parts of beeswax, all scholars 140-180 parts of woods, 140-180 parts of Groomwell root oil and 5-45 parts of lanolin are made.
In the lipstick of adjuvant treatment herpes labialis above-mentioned, calculate by weight, mainly by 70-90 parts of honeysuckle, pueraria lobata 50-70 parts, 30-50 parts of Radix Glycyrrhizae, 0.5-0.9 parts of menthol, 150-170 parts of beeswax, 150-170 parts of vaseline, Groomwell root oil 150- 170 parts and 15-35 parts of lanolin are made.
In the lipstick of adjuvant treatment herpes labialis above-mentioned, calculate by weight, mainly by 80 parts of honeysuckle, pueraria lobata 60 Part, 40 parts of Radix Glycyrrhizae, 0.7 part of menthol, 157.6 parts of beeswax, 157.6 parts of vaseline, 157.6 parts of Groomwell root oil and 22 parts of lanolin system At.
A kind of preparation method of the lipstick of adjuvant treatment herpes labialis above-mentioned, extracting honeysuckle, pueraria lobata, Radix Glycyrrhizae, menthol, Beeswax, vaseline, Groomwell root oil and lanolin, be conventionally made lipstick to get.
The preparation method of the lipstick of adjuvant treatment herpes labialis above-mentioned, extracting honeysuckle, pueraria lobata and Radix Glycyrrhizae add 8-16 times to measure Concentration is alcohol reflux 2 times of 55-75%, and 1.5 hours for the first time, second 1 hour, 0.5-1.5% was added in combined extract Active carbon shakes 1-10min, and filtering, filtrate is condensed into liquid extract, spare;Beeswax and vaseline heating water bath are melted, separately taken The fusing of lanolin heating water bath, adds Groomwell root oil and liquid extract, stirs evenly, be added in the beeswax and vaseline melted, mixes Close uniformly, slightly cold addition menthol mixes, and mixture thread shape pours into sky lipstick shell, room temperature it is cooling to get.
The preparation method of the lipstick of adjuvant treatment herpes labialis above-mentioned, extracting honeysuckle, pueraria lobata and Radix Glycyrrhizae add 12 times of amounts dense Degree is alcohol reflux 2 times of 65%, and 1.5 hours for the first time, second 1 hour, combined extract was added 1% active carbon and shakes 5min, filtering, filtrate is condensed into liquid extract, spare;Beeswax and vaseline heating water bath are melted, lanolin heating water bath is separately taken Fusing, adds Groomwell root oil and liquid extract, stirs evenly, be added in the beeswax and vaseline melted, is uniformly mixed, slightly cold addition Menthol mixes, and mixture thread shape pours into sky lipstick shell, room temperature it is cooling to get.
Honeysuckle, Lonicera japonica are Caprifoliaceae woodbine honeysuckle and congener dry flower or band The flower just opened.Honeysuckle is known as clearing heat and detoxicating good medicine from ancient times.Honeysuckle is cold in nature, sweet in flavor, enters lung, the heart, stomach meridian, has heat-clearing The effect of removing toxic substances, anti-inflammatory, qi-restoratives treat wind, cures mainly disease under turgor, warm disease heating, the diseases such as heat toxin large carbuncle and tumour.It is for giddy Dizziness, thirst, sweating and boring, enteritis, bacillary dysentery, morbilli, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendix The illnesss such as inflammation, skin infection, ulcer boils, erysipelas, parotitis, suppurative tonsillitis have certain curative effect, it was reported that gold and silver Flower has good antivirus action, including herpes simplex virus.Pueraria lobata, Chinese medicine name.For the dry root of legume pueraria lobata, property Taste: it is sweet in flavor, pungent, it is cool in nature.It brings down a fever with expelling pathogenic factors from muscles and skin, the effect of promoting eruption promotes the production of body fluid to quench thirst, Shengyang Zhixie generates heat for exterior syndrome, rigid neck and back Bitterly, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.Radix Glycyrrhizae Glycyrrhiza uralensis Fisch, gas is micro-, sweet and special.Major function is clearing heat and detoxicating, expelling phlegm and arresting coughing, stomach duct and abdomen etc., is chiefly used in asthma and cough.Also have The effect of coordinating the drug actions of a prescription, it was reported that the glycyrrhizin in Radix Glycyrrhizae is known as antivirus action.Groomwell root oil is purple with plant oil extract Chinese medicine Grass and obtain, (main component is alkannin and its derivative) containing alkannin, it is both a kind of phytochrome and Asian puccoon Chinese medicine Effective component, can anti-inflammatory, it is antibacterial, it is antiviral.Light, the thermal stability of alkannin are strong, anti-oxidant, show in acid condition red Color is dissolved in organic solvent, but under alkaline condition, gradually becomes hyacinthine, is dissolved in alkaline water.Alkannin not only safety Height, and color power is strong, and tone is naturally soft, and has pharmacological action, particularly suitable cosmetics coloring.Menthol, lotus brain by It is extracted in the leaf and stem of peppermint, white crystal, molecular formula C10H20O, is the main component in peppermint and lavender essential oil.? In the world, India is main natural peppermint producing country.Menthol and Racementhol can be employed as toothpaste;Perfume;Beverage and The odorant of candy etc..It is used as excitants in medicine, acts on skin or mucous membrane, there is refrigerant itching-relieving action;It is for oral administration to can be used as Carminative, for headache and nose, pharynx, laryngitis etc., using with refrigerant and transdermal facilitation in lipstick.Its ester is for perfume Material and drug.Beeswax, also known as yellow wax, beeswax.Beeswax is the one kind being secreted by 4 pairs of wax glands of worker bee abdomen of the right age in bee colony Fatty matter.Beeswax is a kind of organic compound of complexity.The main component of beeswax is that higher fatty acids and monohydric alcohol are closed At esters, fatty acid and carbohydrate, but because of differences such as honeybee kind, the sources of nectar and pollen, refinement methods, ingredient also has certain difference It is different.Vaseline is the mixture of a kind of methane series hydrocarbon or saturated hydrocarbons semi liquid state, is also vaseline, by being made after petroleum fractionating.All scholars Woods is mainly chemically inert hydrocarbon, and there is no sterilizing abilities;But it is hydrophilic, will not be absorbed, and is applied to skin On can be formed on its surface a tunic, be not easy to evaporate moisture lost, can keep skin be moisture state, stop come from air In bacterium and skin contact, thus a possibility that reducing infection.Lanolin is attached to a kind of secretion grease on wool, is Faint yellow or brown color soft paste;Lanolin is attached to a kind of secretion grease on wool, main component be sterols, The fatty acid ester generated of fatty alcohols and triterpene alcohols and about equivalent, accounts for about 95%, also contains free alcohol 4%, and There are a small amount of free fatty acid and hydrocarbons.Beeswax, vaseline, lanolin are the main matrix parts of this lipstick.
Lipstick is made using above-mentioned supplementary material in the present invention, and each raw material has to act synergistically well, and manufactured lipstick has The effect of certain adjuvant treatment herpes labialis, dry lip harelip, cheilitis;It is hormone-free, it is highly-safe, it has no adverse reaction, and Moisturizing effect is good, and anti-chap effect is good.
To verify beneficial effects of the present invention, inventor has carried out a large amount of experimental study, as follows:
Experimental example:
1. clinical data
Patient 50, between 18-50 years old age, male 22, female 28.Side bicker herpe simplex 38, unilateral lower lip Herpe simplex 11, upper and lower herpes simplex labialis 1.Patient mainly shows: often there are scorching hot, itch and flush from the beginning of part, after And there are dense clusters or several groups of pinhead-sized blisters, it is small compared with the blister of essential and compared with gathering;There is erosion after rupture, seeps Liquid, gradual drying incrustation.
2. treatment method
2.1 groupings: patient is randomly divided into 2 groups, of the present invention group 25 and control group 25.
2.2 systemic comprehensive treatments: two groups take orally clearing heat and detoxicating, antiviral drugs, bland diet, drink more water etc. and to support pair Disease treatment.
2.3 Local treatments: the surface of a wound is cleaned in advance, is avoided using excitant liquid.Of the present invention group of early stage is especially in water Blister forms the phase surface of a wound and uniformly smears lipstick of the present invention (being made by embodiment 1), control group smearing erythromycin ointment, and two groups Coating number is unlimited, to keep the surface of a wound is wet to have medicine as principle.Blister the greater, can be first broken with sterile needle choicest, clear with cotton swab Except secretion;Incrustation person has been formed, lipstick and erythromycin ointment of the present invention has directly been applied outside respectively, is removed after softening, continue to use Medicine is until wound healing.
3 results
Of the present invention group: simple herpes labialis initial stage forms the surface of a wound of blister after lipstick of the present invention treatment, and pain symptom disappears It loses, heals in -10 days 7 days;Extend one 2 days l days when simple herpes labialis incrustation to heal, does not leave pigmentation, color change With formation scar.Without the expansion of the surface of a wound, the complication such as secondary infection in therapeutic process.
Control group: simple herpes labialis initial stage forms the surface of a wound of blister after lipstick of the present invention treatment, and pain symptom is slow Solution heals substantially in -10 days 7 days;Extend -4 days 3 days when simple herpes labialis incrustation to heal, leaves pigmentation, color change With formation scar.Without the expansion of the surface of a wound, the complication such as secondary infection in therapeutic process.
4 conclusions
Lipstick of the present invention, which is treated one 10 days 7 days, to fully recover, and do not leave pigmentation.Treatment cycle is short, can reduce patient's pain Bitter and treatment is convenient, and unconditional to limit, sterility requirements are low, and common patient is easy to grasp.
Part concrete case is as follows:
1, Zhao Dejuan: female, 58 years old, nearly 30 years of long herpes labialis, annual winter recurred 1~3 time, locally burnt from the beginning of upper lip It is heat, itch, rubescent, then grow millet shape bleb, upper lip swelling and pain, rotten to the corn after rupture, sepage, gradual drying incrustation.2015 December in year, once in the morning and once at night, access times increased when discovery lip has burning heat sensation using this product, used before especially sleeping once, Next day burning heat sensation disappears.From using later in December, 2015 in April, 2016 herpes labialis not recur.
2, Wu Jinglan: female, 43 years old, more than 20 years of long herpes labialis, annual winter recurred 1~2 time, recurrence initial stage upper lip part Scorching hot, itch, flush, next day grow dense clusters millet shape bleb, and itch is in great pain, sepage after rupture, continues 1~2 week Dry incrustation.Vitamin B2 is taken when recurrence and antiviral Chinese and Western medicine effect is unobvious, and annual winter can all recur.2015 November uses this product, usually feels to use when lip is dry, feels that frequency of use increases when scorching hot, flush, makes before especially sleeping With, next day is scorching hot, flush improves, continues to use scorching hot, flush and disappear.In November, 2015 has not relapsed so far.
3, Huang Qin: female, 23 years old, in March, 2016, the rubescent cusalgia of the left corners of the mouth, then grew cluster millet shape bleb, used this It forms a scab within bleb 4 days after product, fully recovers within 8th.
Compared with prior art, the lipstick that the present invention assists in the treatment of herpes labialis can be used for assisting in the treatment of herpes labialis, lip Dry harelip, cheilitis;Moisturizing effect is good, and anti-chap effect is good.
Specific embodiment
Embodiment 1:
Prescription: honeysuckle 80g, pueraria lobata 60g, Radix Glycyrrhizae 40g, menthol 0.7g, beeswax 157.6g, vaseline 157.6g, purple Grass oil 157.6g and lanolin 22.5g.
Technique: 65% ethyl alcohol (2160ml) that honeysuckle, pueraria lobata, Radix Glycyrrhizae are measured with 12 times of medicinal material flows back twice, for the first time 1.5 hours, second 1 hour, combined extract was added 1% active carbon and shakes 5min, filters, and filtrate is concentrated to 133g, must flow Medicinal extract is spare.Beeswax and vaseline heating water bath are melted, separately takes lanolin heating water bath to melt, adds Groomwell root oil and liquid extract, It stirs evenly, is added in the beeswax and vaseline melted, be uniformly mixed, slightly cold addition menthol, mix, mixture thread Shape pours into sky lipstick shell, room temperature it is cooling to get.
Usage: it is applied to lip, once in the morning and once at night.
Embodiment 2:
Prescription: honeysuckle 100g, pueraria lobata 80g, Radix Glycyrrhizae 60g, menthol 1.1g, beeswax 180g, vaseline 180g, Groomwell root oil 180g and lanolin 45g.
Technique: extracting honeysuckle, pueraria lobata and Radix Glycyrrhizae, adding 16 times of amount concentration is alcohol reflux 2 times of 75%, and 1.5 is small for the first time When, second 1 hour, combined extract was added 1.5% active carbon and shakes 10min, filters, filtrate is condensed into liquid extract, standby With;Beeswax and vaseline heating water bath are melted, lanolin heating water bath is separately taken to melt, adds Groomwell root oil and liquid extract, stirring is equal It is even, it is added in the beeswax and vaseline melted, is uniformly mixed, slightly cold addition menthol, mix, mixture thread shape pours into Empty lipstick shell, room temperature it is cooling to get.
Usage: it is applied to lip, once in the morning and once at night.
Embodiment 3:
Prescription: honeysuckle 60g, pueraria lobata 40g, Radix Glycyrrhizae 20g, menthol 0.3g, beeswax 140g, vaseline 140g, Groomwell root oil 140g and lanolin 5g.
Technique: extracting honeysuckle, pueraria lobata and Radix Glycyrrhizae, adding 8 times of amount concentration is alcohol reflux 2 times of 55%, and 1.5 is small for the first time When, second 1 hour, combined extract was added 0.5% active carbon and shakes 1min, filters, filtrate is condensed into liquid extract, spare; Beeswax and vaseline heating water bath are melted, separately takes lanolin heating water bath to melt, adds Groomwell root oil and liquid extract, stir evenly, It is added in the beeswax and vaseline melted, is uniformly mixed, slightly cold addition menthol, mix, mixture thread shape pours into sky Lipstick shell, room temperature it is cooling to get.
Usage: it is applied to lip, once in the morning and once at night.

Claims (5)

1. a kind of lipstick for assisting in the treatment of herpes labialis, which is characterized in that it calculates by weight, by 70-90 parts of honeysuckle, pueraria lobata 50-70 parts, 30-50 parts of Radix Glycyrrhizae, 0.5-0.9 parts of menthol, 150-170 parts of beeswax, 150-170 parts of vaseline, Groomwell root oil 150- 170 parts and 15-35 parts of lanolin are made.
2. the lipstick of adjuvant treatment herpes labialis as described in claim 1, which is characterized in that calculate by weight, by gold and silver Spend 80 parts, 60 parts of pueraria lobata, 40 parts of Radix Glycyrrhizae, 0.7 part of menthol, 157.6 parts of beeswax, 157.6 parts of vaseline, 157.6 parts of Groomwell root oil And 22 parts of lanolin be made.
3. a kind of preparation method of the lipstick of adjuvant treatment herpes labialis as claimed in claim 1 or 2, it is characterised in that: take Honeysuckle, pueraria lobata, Radix Glycyrrhizae, menthol, beeswax, vaseline, Groomwell root oil and lanolin, be conventionally made lipstick to get.
4. the preparation method of the lipstick of adjuvant treatment herpes labialis as claimed in claim 3, it is characterised in that: extracting honeysuckle, Pueraria lobata and Radix Glycyrrhizae, adding 8-16 times to measure concentration is alcohol reflux 2 times of 55-75%, 1.5 hours for the first time, second 1 hour, is merged Extracting solution is added 0.5-1.5% active carbon and shakes 1-10min, filters, filtrate is condensed into liquid extract, spare;By beeswax and Fan Shi The fusing of woods heating water bath, separately takes lanolin heating water bath to melt, adds Groomwell root oil and liquid extract, stir evenly, be added to and melt Beeswax and vaseline in, be uniformly mixed, slightly cold addition menthol, mix, mixture thread shape pours into sky lipstick shell, and room temperature is cold But to get.
5. the preparation method of the lipstick of adjuvant treatment herpes labialis as claimed in claim 4, it is characterised in that: extracting honeysuckle, Pueraria lobata and Radix Glycyrrhizae, adding 12 times of amount concentration is alcohol reflux 2 times of 65%, 1.5 hours for the first time, second 1 hour, merges and extracts Liquid is added 1% active carbon and shakes 5min, filters, filtrate is condensed into liquid extract, spare;Beeswax and vaseline heating water bath are melted Change, separately takes lanolin heating water bath to melt, add Groomwell root oil and liquid extract, stir evenly, be added to the beeswax and Fan Shi melted Lin Zhong is uniformly mixed, slightly cold addition menthol, is mixed, and mixture thread shape pours into sky lipstick shell, room temperature it is cooling to get.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101987116A (en) * 2009-08-06 2011-03-23 吕月菊 Chinese medicinal extract for treating viral herpes and preparation thereof
CN104983613A (en) * 2015-06-20 2015-10-21 俞华 Moisturizing lip balm and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101987116A (en) * 2009-08-06 2011-03-23 吕月菊 Chinese medicinal extract for treating viral herpes and preparation thereof
CN104983613A (en) * 2015-06-20 2015-10-21 俞华 Moisturizing lip balm and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"薄层扫描法测定口涳宝中绿原酸含量";王瑞明等;《时珍国医国药》;20031231;第14卷(第6期);第334-335页 *

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