CN101653552A - Smoke-quitting alexeteric traditional Chinese medicine preparation and production method thereof - Google Patents
Smoke-quitting alexeteric traditional Chinese medicine preparation and production method thereof Download PDFInfo
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Abstract
The invention discloses a smoke-quitting alexeteric traditional Chinese medicine preparation and a production method thereof. A liquid medicine or lozenges are prepared by the water cooking, the aqueous extraction and the alcohol extraction of pumpkin vines, ordate houttuynia, mint, ophiopogon roots, polygala and herba abri, and a cigarette addict can relieve smoke addiction within 3-5 days by dripping the liquid medicine on the tongue, gargling, sucking or taking the liquid medicine orally for a plurality of times every day. The liquid medicine has no toxic and side effect on the liver, the stomach and the lungs, is safe and effective without stimulation and sensitization, has the effects of resisting bacteria, removing toxicity, protecting the liver, promoting urination, calming the nerves, nourishing the blood, clearing away heat and toxic material, and the like, and can promote smoke poison metabolism and relieve the smoke addiction, thereby achieving the aim of thoroughly quittingsmoking.
Description
Technical field
The present invention relates to a kind of Chinese medicine of giving up craving for tobacco, particularly can give up the Chinese medicine preparation and the production method thereof of the Chinese medicine and the heat-clearing and toxic substances removing of craving for tobacco simultaneously.
Background technology
Smoking is one of dead early major reason of human ill, anergy, DB, when you are firing the Linear Leaf Speedwell cigarette, you just begin to suck the different chemical substance of kind more than hundred, wherein with nicotine, tar, carbon monoxide and other carcinogen are maximum to the human body infringement.The main chemical substance that medicated cigarette discharges in combustion process has tens kinds, as nicotine, tar, carbon monoxide, benzopyrene etc., after chemical substance in the smoke from cigarette directly and indirectly is absorbed by the body, to cardiovascular, breathing, digestion, nervous system with to fetus etc. certain influence is arranged all, nicotine and tar content in the medicated cigarette are higher, can cause multiple diseases such as pulmonary carcinoma, hypertension, diabetes, limb vessel sclerosis, angina pectoris, apoplexy.If the non smoker lives in the smoker, also the toxic chemical substance in the smog is spread in family in the time of smoker's smoking, bring harm to the non smoker, particularly women and children are endangered even more serious, at women's phenolics, can influence the fetus nutrient absorb and grow, the baby that order is given birth to is can more common baby light even cause miscarrying, the intelligence disability appears in the baby.
For a long time, all ban on opium-smoking and the opium trade in the harm of propaganda Nicotiana tabacum L. in all parts of the world, the Tobacco Control association of World Health Organization (WHO) and China, all done a lot of work, formulate the policy of some Tobacco Controls through discussion, the series decision-making of reversing global Nicotiana tabacum L. policy has also been released in the whole world specially, China has translated into Chinese in disease control and prevention center, wish also that by this strategy national governments can make a series of regulation at aspects such as formulating Nicotiana tabacum L. policy, raising Nicotiana tabacum L. tax revenue, raising attention Nicotiana tabacum L. sign, China has also formulated the clinical smoking cessation guide of China.By Western medicine, Chinese herbal medicine and a lot of mode, take for the people of craving for tobacco, many people have successfully given up craving for tobacco by taking medicine, have obtained achievement preferably, have reduced the disease that causes because of smoking to a certain extent.Through the retrieval scientific and technical literature, people have used multiple Chinese herbal medicine to give up smoking at present, for example:
1, Chinese patent, application number: 93101974.5 titles: compound gargle for giving up smoking, open (bulletin) number: CN1079894 applies for (patent right) people: Weng Weijian, disclose a kind of Gargling water for giving up smoking, it is made up of fluid extract and glycerol, the distilled water of Rhizoma Picrorhizae, Folium Camelliae sinensis, Herba Houttuyniae, Pericarpium Citri Reticulatae, Rhizoma Acori Graminei, Radix Polygalae, Radix Ginseng, Poria.
2, Chinese patent, application number: 200610009916.9 titles: external applied stop smoking massage liquid and preparation technology thereof, open (bulletin) number: CN101053606 applies for (patent right) people: Wang Yumin, this product external applied stop smoking massage liquid, its composition comprises: Radix Polygalae, Poria, Caulis Polygoni Multiflori, Radix Platycodonis, Radix Pseudostellariae, Pheretima, Herba Houttuyniae, Herba Pogostemonis, Radix Glycyrrhizae, Chinese liquor, the parts by weight of described Radix Polygalae are 2-8, the parts by weight of described Poria are 8-15, the parts by weight of described Caulis Polygoni Multiflori are 5-10, the parts by weight of described Radix Platycodonis are 3-9, the parts by weight of described Radix Pseudostellariae are 9-15, the parts by weight of described Pheretima are 5-15, the parts by weight of described Herba Houttuyniae are 15-30, the parts by weight of described Herba Pogostemonis are 3-9, described Radix Glycyrrhizae parts by weight are 3-9, described Chinese liquor parts by weight are 200-400.
3, Chinese patent, application number: 200510020132.1 titles: a kind of smoking abstention method, open (bulletin) number: CN1799589 applies for (patent right) people: Liu Yuedong, a kind of method of smoking cessation may further comprise the steps: with Pheretima 10-20 part, and Radix Sanguisorbae 10-20 part, Herba Houttuyniae 10-20 part, Radix Polygalae 10-20 part with 500 parts of two weeks of soaking in Chinese liquor, is mixed with medicated wine; Medicated wine is spread upon on the acupuncture point of two hands correspondences, be placed on respectively on the acupuncture point that just had been coated with medicated wine with two electrodes of low-frequency electric pulse then and get final product.Smoking cessation process of the present invention has no adverse reaction, and success rate is good, and relapse rate is low, does not have craving for tobacco after the smoking cessation again, the craving for tobacco that more can not happen suddenly, and smoke and anyly all can feel pained, thus medicated cigarette produced dislike from the physiology and reach the purpose of smoking cessation.
4, Chinese patent, application number: 200610009713.X title: a kind of candy for stopping smoking and preparation method, open (bulletin) number: CN101019957 applies for (patent right) people: Zhang Liqing, a kind of candy for stopping smoking and preparation method, this candy for stopping smoking is by the Chinese herbal medicine Radix Ginseng, Radix Polygalae, Pheretima, Herba Houttuyniae and xylitol slurry, gum base constitutes, the preparation method of this candy for stopping smoking is: at first get Radix Ginseng's 15 grams, Radix Polygalae 45 grams, Pheretima 45 grams, Herba Houttuyniae 50 gram roguings, clean and to put into jar and add 800-1000 gram clean water and carry out decocting the first time 20 minutes after-filtration to go out medicinal liquid stand-by, adding 1000-1200 gram clean water again carries out decocting the second time 30 minutes after-filtration to go out medicinal liquid stand-by, adding 1200-1500 gram clean water again decocts 40 minutes after-filtration for the third time to go out medicinal liquid stand-by, the medicinal liquid that leaches for three times is lumped together, add xylitol slurry 80 grams simultaneously and gum base 20 grams stir, shakeout with the fiery decocting and concentrating of stricture of vagina to paste taking-up, cooling, be packaged to be after the stripping and slicing cooling.
The deficiency that above-mentioned disclosed smoking abstention method or medicine exist is that the prescription that has is complicated, need make product as cigarette and light a fire for craving for tobacco person to inhale clothes; What have can not make smoking cessation thoroughly, and easily repeatedly, it is difficult to apply.
Summary of the invention
The purpose of this invention is to provide a kind of good effect of giving up smoking, be difficult for repeatedly, and it is simple, easy to use to have a prescription, do not need to light a fire and inhale the smoking cessation traditional Chinese medicine liquid (tongue dips in agent or collutory) of clothes; This medicinal liquid also has antipyretic and antidote functions (Chinese medicine for oral administration medicinal liquid) simultaneously on the smoking cessation basis.
Smoke-quitting alexeteric Chinese medicine preparation of the present invention is to be made by following raw material of Chinese medicine, and the parts by weight of its composition and dry are as follows:
Caulis Cucurbitae 20-30 part;
Herba Houttuyniae 20-30 part;
Radix Ophiopogonis 15-20 part;
Radix Polygalae 10-15 part;
Herba Menthae 3-5 part;
Herba Abri 0-15 part.
The production method of the Chinese medicine of withdrawal craving for tobacco of the present invention and the medicinal liquid of heat-clearing and toxic substances removing is with fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smashes, and adds 3-5 times of clear water by weight and boils 10-20 minute, filters out medicinal liquid, and is standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, and adds an amount of food preservative, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Above-mentioned Caulis Cucurbitae, Herba Houttuyniae and Herba Menthae can also can be adopted dry product with leaf or herb.
The production method preparation method of the Chinese medicine of smoking cessation Chinese medicine preparation withdrawal craving for tobacco of the present invention and the medicinal liquid of heat-clearing and toxic substances removing also can adopt or water is put forward the method that adds alcohol extraction again, specific as follows: the fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, adding 3-5 times of clear water by weight boiled 0.5-1 hour, Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 0.5-1 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter out medicinal liquid, standby, all medicinal residues add immersion 3-5 hour of spirituosity weight concentration 35-70% by weight, recovery of alcohol distillation, liquid and above-mentioned all filtering liquid medicines merge, and add an amount of food preservative, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Product of the present invention can also be made buccal tablet, and preparation method is as follows:
With fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smash, add 3-5 times of clear water by weight and boiled 10-20 minute, filter out medicinal liquid, standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, per 100 kilograms of medicinal liquids add sucrose 5-10 kilogram, cyclodextrin 3-5 kilogram, carboxymethyl cellulose 2-5 kilogram, mix homogeneously, spray drying, add magnesium stearate, send into the bottling of tablet machine tablet forming, or be hot pressed into aluminium-plastic panel, carton package gets product.
Below be the essential information of the raw material of Chinese medicine composition of smoke-quitting alexeteric Chinese medicine preparation of the present invention:
Caulis Cucurbitae claims Radix Cucurbitae again, is cucurbitaceous plant Fructus Cucurbitae moschatae rhizome (comprising tender leaf or old stem).Fructus Cucurbitae moschatae, Cucurbitaceae (Cucurbitaceae) Cucurbita (Cucurbita), annual herb.Can use musky gourd (C.moschata), Cucurbita maxima (C.maxima) or Cucurbita pepo L. (american pumpkin) (C.pepo), [effect cures mainly] clearing heat and moistening lung, suppressing the hyperactive liver and easing the stomach and blood yin nourishing.Control the pulmonary tuberculosis low grade fever, stomachache, menoxenia is scalded;
Herba Houttuyniae has another name called Ji dish, folding ear dish, and Herba Houttuyniae (herba houttuyniae) is the dry above water of Saururaceae herbaceos perennial Herba Houttuyniae, and Herb tool fishy smell can be stir-fried and eaten, cold and dressed with sauce or make soup.Doctor among the people thinks mostly, and its property and flavor of peppery and cold has heat-clearing and toxic substances removing, detumescence and apocenosis, diuresis and gushes effects such as pouring, can be used for treating diseases such as lung pyosis infections, lung-heat cough with asthma, hematodiarrhoea pyretic stranguria, edema, beriberi, urinary tract infection, leukorrhagia, carbuncle sore tumefacting virus.So Herba Houttuyniae often becomes the principal agent of relevant pneumonopathy, diseases of urinary system in tcm prescription.Modern medicine by analysis, the characteristic odor of Herba Houttuyniae is mainly derived from a kind of effective ingredient in the Herba Houttuyniae volatile oil---houttuynine sodium bisulfite (decanoylacetaldehyde).The Herba Swertiae davidi element is the main antimicrobial component of Herba Houttuyniae, and micrococcus catarrhalis, hemophilus influenza, streptococcus pneumoniae, staphylococcus aureus etc. are had obvious inhibitory action.In addition, Herba Houttuyniae also contains effective ingredient such as quercitrin, has antiviral and diuresis.Clinical practice proves: Herba Houttuyniae all has curative effect preferably for upper respiratory tract infection, bronchitis, pneumonia, chronic tracheitis, chronic cervicitis, pertussis etc., and acute conjunctivitis, urinary tract infection etc. is also had certain curative effect.In addition, Herba Houttuyniae can also the enhancing human body immunity function, and the leukocyte increasing phagocytic activity has analgesia, cough-relieving, hemostasis, promotes tissue regeneration, the effect of aspects such as expansion blood capillary, blood flow increasing.
Be the tuber of liliaceous plant Ophiopogon Radix Ophiopogonis japonicus (Thunb.) Ker-Gawl. Radix Ophiopogonis, and [property of medicine] sweet, little hardship is slightly cold.Return stomach, lung, heart channel.[effect] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Sweet in the mouth is soft and moist, and the inclined to one side bitter cold of property is longer than nourishing stomach-YIN, promoting the production of body fluid to quench thirst, the clearing away stomach-heat of holding concurrently.The kind again lung yin of supporting of this product, clearing away lung-heat is applicable to that lung-dryness syndrome due to deficiency of YIN has the dryness in the nasal cavity dry pharynx of heat, few, the hemoptysis of dry cough expectorant, but GUIXIN warp, the moon that can also nourish heart, the heat that clears away heart-fire, and omit tool relieving restlessness sedative action.Also can be used for deficiency of heart-yin and have diseases such as vexed, the insomnia and dreamful sleep of heat, forgetful, severe palpitation.Chemical constituent: this product contains compositions such as multiple steroidal saponin, cupreol, stigmasterol, homoisoflavone compounds, several amino acids, various types of polysaccharide, vitamin A sample material, copper, zinc, ferrum, potassium.Pharmacological action: can strengthen reticuloendothelial system phagocytic activity Radix Ophiopogonis, and the rising peripheral leukocytes improves immunologic function; Can strengthen the pituitary adrenal system effect, improve organism adaptation; Can significantly improve the laboratory animal hypoxia-bearing capability, increase coronary flow, myocardial ischemia is had obvious protective effect, and can arrhythmia and improve myocardial contraction; The left ventricular function of improvement and Antishock function are arranged; Also have certain calmness and antibacterial action.
Radix Polygalae is the dry root of milk wort Radix Polygalae Polygala tenuifolia Willd. or ovum leaf Radix Polygalae Polygala sibiricaL..Main product in Shanxi, ground such as Shaanxi, Jilin, Henan, Hebei.Emerge spring preceding or autumn aerial parts withered after, take root, remove fibrous root and silt, dry.Give birth to or process usefulness.[property of medicine] is bitter, hot, temperature.GUIXIN, kidney, lung meridian.[effect] Fructus Alpiniae Oxyphyllae of calming the nerves is eliminated the phlegm and is had one's ideas straightened out, the dissipation carbuncle.Be used for insomnia and dreamful sleep, severe palpitation, forgetful, epilepsy mania and irritation, cough with copious phlegm, skin sore, breast swell and pain, sore throat.Chemical constituent: this product contains saponin, can get Radix Polygalae sapogenin A and Radix Polygalae sapogenin B after the hydrolysis.Also contain Radix Polygalae ketone, alkaloid, glucide, polygalytol, tenuidine, fatty oil, resin etc.Pharmacological action: full Radix Polygalae has calmness, hypnosis and anticonvulsant action.Polygalic acid eliminates the phlegm, antitussive, hypotensive effect; Decoct all has excitation to rat and stripped unpregnancy and the pregnant uterus of mice; The ethanol immersion all has obvious inhibitory action external to gram positive bacteria and dysentery bacterium, Bacillus typhi, Bacillus tuberculosis; Its decoct and water solubility extract have effects such as defying age, mutation be anticancer respectively; Polygalic acid has haemolysis.
Herba Menthae, Latin language formal name used at school: Mentha haplocalyx (Briq.var.piperascens Malinvaud), Chinese another name: cease perfume, tomentosecalyx elsholtzia leaf (Sichuan), water Herba Leonuri, spices (Guangxi) etc. at wild mint, night.Herba Menthae is a kind of fragrant crop that extraordinary economic worth is arranged for to be the aerial parts of Labiatae (Labiatae) perennial perennial root herbaceous plant Mentha (Mentha).Herba Menthae product (Mentholum and Oleum menthae) has special fragrance, pungent sense and cool sense, is mainly used in the perfuming of toothpaste, food, Nicotiana tabacum L., wine, refreshment drink, cosmetics, fancy soap; In pharmaceutically being widely used in wind dispelling, anticorrosion, antiinflammatory, analgesia, antipruritic, medicine such as be good for the stomach.All herbal medicine, suffering, cold.Return lung, Liver Channel, the wind heat of dispersing is arranged, clearing throat, the rash detoxifcation, dispersing the stagnated live-QI to relieve the stagnation of QI and effect such as antipruritic, be applicable to that cold, fever, headache, laryngopharynx swelling and pain, lossless, wind-fire acute conjunctivitis, rubella, skin are itched, disease such as colic, dysentery and scrofula, external has slight analgesic effect, is used for neuralgia etc.
Herba Abri, [formal name used at school] Herba Abri, [another name] Caulis et Folium Desmodii Gangetici, crossdrift bank, yellow food grass, spire Herba Titanotrichi oldhamii, Radix Et Rhizoma Rhei [base is former] this product are the dry Herb of leguminous plant abrus cantoniensis Hance Abrus cantoniensis Hance.All can excavate the whole year, removes silt, drying.Herba Abri Herba Abri cantoniensis main product in Bao'an in area, Nanning and Guangdong, county such as Dongguan, Shuande.[chemical constituent] herb contains abrine (Abrine, i.e. N-methyl-tryptophane), choline (Choline), sterol compound, flavonoid, aminoacid, saccharide.Herb contains abrine (L-abrine, N-methyl-tryptophane), flavonoid glycoside, choline (choline), sterol, aminoacid, saccharide.[meridian distribution of property and flavor] sweet, little hardship, cold.Return liver, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, Shugan Zhitong.Be used for jaundice, side of body rib does not relax the gastral cavilty distending pain; Acute and chronic hepatitis, mastitis.Because Herba Abri has heat-clearing and toxic substances removing, toxin expelling and the effect of treatment hepatitis, has developed Chinese medicine preparation such as Herba abri capsule, Herba Abri hepatitis granule, Herba Abri hepatitis electuary, Herba Abri hepatitis ball at present.
Wood invention product consumption and usage: get this product medicinal liquid, each 6-10ml drips on lingual surface, tells in 1-2 minute to get final product.Also medicinal liquid can be put in the container, add 10 times in clear water, shake up, this water of reuse is gargled repeatedly, till having gargled.Shared 3 times of every day.Perhaps use buccal tablet, each nicotine fit is a buccal.After using this medicinal liquid or buccal tablet,, logotype 10-20 days, just can successfully give up smoking even produce disagreeable malice during craving for tobacco person's smoking.
If smoke-quitting alexeteric Chinese medicine preparation of the present invention is for oral administration, also can realize smoking cessation, can also treat diseases such as pneumonia, hepatitis, cough with copious phlegm.
Product of the present invention detects through scientific research departments such as Guangxi traditional Chinese medical science research department experiments, and the prolonged application effect shows that this product is without any side effects and become carcinous, and has the symptom that is presented when resisting the giving up of morphine.Use this product smoking cessation effect by hundreds of smokers and show that take effect in most of weeks, two weeks initiatively stops smoking, it is latent just can to give up cigarette in one month,
The advantage of smoke-quitting alexeteric Chinese medicine preparation of the present invention:
1, adopts pure Chinese medicine preparation, eating dual-purpose medical material with traditional doctor is raw material, reasonable compatibility, scientific matching are prepared from, have no side effect, non-stimulated, no sensitization, safe and effective, have effects such as antibiotic, detoxifcation, diuresis, tranquilizing and blood nourishing, can promote the metabolism of body tobacco poisoning, remove craving for tobacco, thereby reach the purpose of thorough smoking cessation.
2, it is simple, easy to use to have a prescription, does not need igniting to inhale clothes; This medicinal liquid also has antipyretic and antidote functions, particularly Herba Abri simultaneously and has heat-clearing and toxic substances removing, toxin expelling and the effect of treatment hepatitis on the smoking cessation basis, so medicinal liquid of the present invention has the effect of hepatoprotective and treatment hepatitis B.
3, product of the present invention proves through studies on acute toxicity and slow phase toxicity research and clinical trial, is safe by intending with using the daily dose and the course of treatment product of the present invention.
The specific embodiment
Below be embodiments of the invention:
Embodiment one:
Take by weighing following Chinese medicine ingredients (unit: g)
Caulis Cucurbitae 25 grams; Herba Houttuyniae 25 grams; Restrain Radix Ophiopogonis 15; Radix Polygalae 15 grams; Herba Menthae 5 grams;
With fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smash, add 3-5 times of clear water by weight and boiled 10-20 minute, filter out medicinal liquid, standby; The dry medical material of Radix Ophiopogonis and Radix Polygalae, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, and adds an amount of food preservative potassium sorbate, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Embodiment two:
Take by weighing following Chinese medicine ingredients (unit: g)
Caulis Cucurbitae 20 grams; Herba Houttuyniae 20 grams; Restrain Radix Ophiopogonis 15; Radix Polygalae 10 grams; Herba Menthae 2 grams; Herba Abri 10 grams;
With fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smash, add 3-5 times of clear water by weight and boiled 10-20 minute, filter out medicinal liquid, standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, and adds an amount of food preservative Nipagin ester, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Embodiment three:
Take by weighing following Chinese medicine ingredients (unit: g)
Caulis Cucurbitae 30 grams; Herba Houttuyniae 30 grams; Restrain Radix Ophiopogonis 20; Radix Polygalae 15 grams; Herba Menthae 4 grams;
Fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, adding 3-5 times of clear water by weight boiled 0.5-1 hour, the dry medical material of Radix Ophiopogonis and Radix Polygalae, adding 3-5 times of clear water by weight boiled 0.5-1 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter out medicinal liquid, standby, all medicinal residues add immersion 3-5 hour of spirituosity weight concentration 35-70%, recovery of alcohol distillation by weight, liquid and above-mentioned all filtering liquid medicines merge, add an amount of food preservative, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Embodiment four:
Take by weighing following Chinese medicine ingredients (unit: g)
Caulis Cucurbitae 200 grams; Herba Houttuyniae 300 grams; Restrain Radix Ophiopogonis 150; Radix Polygalae 100 grams; Herba Menthae 50 grams; Herba Abri 100 grams;
Fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, adding 3-5 times of clear water by weight boiled 0.5-1 hour, Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 0.5-1 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter out medicinal liquid, standby, all medicinal residues add immersion 3-5 hour of spirituosity weight concentration 35-70%, recovery of alcohol distillation by weight, liquid and above-mentioned all filtering liquid medicines merge, add an amount of food preservative potassium sorbate, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Embodiment five:
Take by weighing following Chinese medicine ingredients (unit: g)
Caulis Cucurbitae 200 grams; Herba Houttuyniae 200 grams; Restrain Radix Ophiopogonis 150; Radix Polygalae 100 grams; Herba Menthae 20 grams; Herba Abri 5 grams;
With fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smash, add 3-5 times of clear water by weight and boiled 10-20 minute, filter out medicinal liquid, standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dried medical material, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, and adds an amount of food preservative sodium benzoate, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Embodiment six:
Take by weighing following Chinese medicine ingredients (unit: g)
Caulis Cucurbitae 150 grams; Herba Houttuyniae 300 grams; Restrain Radix Ophiopogonis 100; Radix Polygalae 180 grams; Herba Menthae 50 grams; Herba Abri 80 grams.
Fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, adding 3-5 times of clear water by weight boiled 0.5-1 hour, Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 0.5-1 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter out medicinal liquid, standby, all medicinal residues add immersion 3-5 hour of spirituosity weight concentration 35-70%, recovery of alcohol distillation by weight, liquid and above-mentioned all filtering liquid medicines merge, add an amount of food preservative Nipagin ester, bottling obtains smoke-quitting alexeteric medicinal liquid product.
Embodiment seven:
Take by weighing following Chinese medicine ingredients (unit: g)
Fructus Cucurbitae moschatae Herb (tender leaf and root) 250 grams; Herba Houttuyniae 300 grams; Restrain Radix Ophiopogonis 100; Radix Polygalae 150 grams; Herba Menthae 100 grams; Herba Abri 100 grams;
With fresh pumpkin tender leaf and root, Herba Houttuyniae and Herba Menthae, smash, add 3-5 times of clear water by weight and boiled 20-30 minute, filter out medicinal liquid, standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, add 3-5 times of clear water by weight and boiled 1-2 hour, filter out medicinal liquid, add water boil 0.5-1 hour for the second time, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, and per 100 kilograms of medicinal liquids add sucrose 5-10 kilogram, cyclodextrin 3-5 kilogram, carboxymethyl cellulose 2-5 kilogram, mix homogeneously, spray drying adds magnesium stearate, send into the tablet machine tablet forming bottle product.
Smoke-quitting alexeteric traditional Chinese medicine preparation product result of use of the present invention:
Data and method
1.1 physical data
Man's 60 examples, women 8 examples comprise civil servant, the worker of enterprise, medical personnel and teacher etc., the age: average 45 years old of smoking group, in year smoking group smoking time (8-20), smoking every day number (9-16) props up.No hypertension, medical histories such as the heart, brain, kidney.
1.2 method
In 60 examples, great majority are about 20.16 people are arranged once with distinct methods smoking cessation success more than twice, have the attitude of trying specifically in arms and participate in.
The preparation of 2 smoking deterents
21 use the medicinal liquid of embodiment of the invention 1-5.
2.2 consumption and usage: when thinking smoking, taking liquid, each 6-10ml drips on lingual surface, tells in 1-2 minute to get final product.Also medicinal liquid can be put in the container, add 10 times in clear water, shake up, this water of reuse is gargled repeatedly, till having gargled.After using this medicinal liquid, even produce disagreeable malice during craving for tobacco person's smoking, logotype 10-20 days,
4 therapeutic outcomes
4.1 evaluation criterion physiology smoking cessation: the back withdrawal symptom basic solution of giving up smoking removes, no general malaise and misery, and two days smoking desires are still deposited, and desire disappears substantially after 5 days, gives up smoking or the suction amount subtracts greatly, is no more than 5 every day; Smoking cessation fully: no longer smoking; The addiction again of reverting to take drugs: surpass 10 persons every day; Invalid: the cigarette amount does not have big variation before and after the medication.
4.2 result's 60 philtrums, oral cavity to the smoke paraesthesia, stop cigarette or the cigarette amount that die-offs after accommodate 39 painful people invariably, reach physiology ES 53 people, account for 83%; Wherein reach 48 people of smoking cessation fully, account for 80%; Reach psychological ES 33 people, account for 55%; Addiction person 7 people that revert to take drugs again, invalid 3 people.
4.3 do not have irritatedly during the side effect medication, do not find other untoward reaction. and diseases such as the former bitter taste of most reflections, dry pharynx, chest pain, cough remit improvement, and appetite increases, and sleep improves.
4.4 antipyretic and antidote functions is in 58 examples, because the long-term smoking that has, throat pain appears mostly, cough, excessive phlegm, 3 people have hepatitis, and there is inflammation in 6 people pulmonarys, therapeutic process, there is the part patient that medicinal liquid is for oral administration, every day 3 times, each 100-200 milliliter, after 20 days, most of throat pain, cough sx, hepatitis 2 people's symptoms take a turn for the better, and pulmonary has 5 people of inflammation that improvement is in various degree arranged.
5 model cases
The king *, man, 65 years old, Nanning city retired cadre, 38 year day of length of smoking 20～40 of smoking capacities, smoking cessation successively is all successes repeatedly, because lung inflammation, cough, adopt medicinal liquid of the present invention (embodiment 1) to gargle and gave up smoking in 3 days (just gargling when thinking smoking), the 3rd day sensation of medication smoke becomes pained, the big cunning of later cigarette strength, non-smoking is not irritable yet, inhale on the contrary again and feel sick, in addition dizzy, so continue medication, except that the method for gargling, also 200 milliliters for oral administration of every day, the cough of smoking cessation back takes a turn for the better, back spirit, sleep, diet all improve, and weight increase was 5 kilograms in one month.
Horse * *, man, 48 years old, Fusui county civil servant, smoking every day 30-50 props up, and the people claims the cigarette addict, the household tries to stop repeatedly, 2 the successes of giving up smoking, the medicinal liquid of the use embodiment of the invention five, when thinking smoking, each 6-10ml drips on lingual surface, told in 1-2 minute, the aftersensation smoke became pained in 2 days, and smoking feels under the weather, logotype 15 days is given up smoking successfully.
Yellow * *, man, 36 years old, Yongning, Guangxi county Liu Xu town peasant, smoking every day 20-40 props up, because throat pain occurs, the cough symptom, excessive phlegm is yellowish-brown, once gave up smoking more than 10 time, used candy for stopping smoking, the smoking deterent that sell in the shop etc., all unsuccessful, can not do strong physical work, use the medicinal liquid of the embodiment of the invention two, every day 5 times, each 50-100ml, add an amount of sucrose, buccal (general stop mouthful in about 1 minute) slowly, the aftersensation smoke became pained in 3 days, smoking feels under the weather, throat pain is given up smoking successfully in logotype 15 days, cough, excessive phlegm transference cure, health are strong gradually.
Clock * *, man, 37 years old, Foshan city Nanhai District medicine distributor, about 30 of smokings every day suffer from hepatitis B, frequent hepatalgia, face's yellowish-brown, inappetence, also once gave up smoking repeatedly, but be difficult to give up, used the buccal tablet of the embodiment of the invention seven, craving for tobacco promptly contains, embodiment 2 medicinal liquids also for oral administration, each 50-100ml, buccal (general stop mouthful in about 1 minute) slowly, the aftersensation smoke became pained in 3 days, and smoking feels under the weather, logotype 10 days is given up smoking successfully, and appetite takes a turn for the better, reuse 20 days, sensation hepatalgia transference cure, physical recovery health, the himself takes the buccal tablet of inventor's configuration back trial sale, buy craving for tobacco person and use, respond well.
Deep * *, woman, 21 years old, Liuzhou people from city, the shop service man is because impunity and friend's chat After Hours, smoking causes craving for tobacco more than 2 years, and daytime, working needed smoking to regain consciousness, the desire smoking cessation upon somebody's introduction, is used the buccal tablet of the embodiment of the invention seven, craving for tobacco promptly contains, the back craving for tobacco elimination of one week, working no longer needs smoking, and work is happy.
6 discuss
Nicotine in 61 Nicotiana tabacum L.s can cause smoker's addiction, because the degree of nicotine dependence is not so good as heroin or cocaine is serious, has willpower and resolution to need not treatment with regard to giving up as long as a lot of people thinks.But because nicotine dependence has the basic characteristics of addictive disorders, equally will be in the face of such as problem such as withdrawal symptom such as easily enrage, vexed, fidgety, absent minded and crave in the therapeutic process.Therefore, be not stranghtforward for ES's treatment, and need the Comprehensive Treatment of system.The medicinal liquid that Caulis Cucurbitae among the side of the present invention, Herba Houttuyniae, Radix Ophiopogonis, Radix Polygalae, Herba Menthae are formed have suffering, temperature, hardship and to liver, helmet, lung, have no side effect, non-stimulated, no sensitization, safe and effective, have effects such as antibiotic, detoxifcation, hepatoprotective, diuresis, tranquilizing and blood nourishing, can promote the metabolism of body tobacco poisoning, remove craving for tobacco, thereby reach the purpose of thorough smoking cessation, also have antipyretic and antidote functions.
Claims (4)
1, a kind of smoke-quitting alexeteric Chinese medicine preparation is characterized in that: it is to be made by following raw material of Chinese medicine, and the parts by weight of its composition and dry are as follows:
Caulis Cucurbitae 20-30 part;
Herba Houttuyniae 20-30 part;
Radix Ophiopogonis 15-20 part;
Radix Polygalae 10-15 part;
Herba Menthae 3-5 part;
Herba Abri 0-15 part.
2, the production method of smoke-quitting alexeteric Chinese medicine preparation as claimed in claim 1 is characterized in that: with fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smashes, adds 3-5 times of clear water by weight and boiled 10-20 minute, filter out medicinal liquid, and standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, and adds an amount of food preservative, bottling obtains smoke-quitting alexeteric medicinal liquid product.
3, the production method of smoke-quitting alexeteric Chinese medicine preparation as claimed in claim 1, it is characterized in that: with the fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, adding 3-5 times of clear water by weight boiled 0.5-1 hour, Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 0.5-1 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter out medicinal liquid, standby, all medicinal residues add immersion 3-5 hour of spirituosity weight concentration 35-70% by weight, recovery of alcohol distillation, liquid and above-mentioned all filtering liquid medicines merge, and add an amount of food preservative, bottling obtains smoke-quitting alexeteric medicinal liquid product.
4, the production method of smoke-quitting alexeteric Chinese medicine preparation as claimed in claim 1 is characterized in that: with fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae, smashes, adds 3-5 times of clear water by weight and boiled 10-20 minute, filter out medicinal liquid, and standby; Radix Ophiopogonis, Radix Polygalae and Herba Abri are used dry medical material, adding 3-5 times of clear water by weight boiled 1-2 hour, filter out medicinal liquid, for the second time add water boil 0.5-1 hour, filter waste, the medicinal liquid that twice medicinal liquid and fresh pumpkin rattan, Herba Houttuyniae and Herba Menthae cook merges, per 100 kilograms of medicinal liquids add sucrose 5-10 kilogram, cyclodextrin 3-5 kilogram, carboxymethyl cellulose 2-5 kilogram, mix homogeneously, spray drying, add magnesium stearate, send into the bottling of tablet machine tablet forming, or be hot pressed into aluminium-plastic panel, carton package gets product.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102100329A (en) * | 2011-01-12 | 2011-06-22 | 兰德吉 | Food composition and preparation method and application thereof |
| CN104224926A (en) * | 2014-09-15 | 2014-12-24 | 中国人民解放军第二军医大学 | Traditional Chinese medicine extract for removing cigarette and wine toxins as well as preparation method and application thereof |
| CN112704694A (en) * | 2021-01-30 | 2021-04-27 | 天赋康(温州)生物科技有限公司 | Smoking cessation oral liquid and preparation method thereof |
-
2009
- 2009-09-07 CN CN2009101143726A patent/CN101653552B/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102100329A (en) * | 2011-01-12 | 2011-06-22 | 兰德吉 | Food composition and preparation method and application thereof |
| CN104224926A (en) * | 2014-09-15 | 2014-12-24 | 中国人民解放军第二军医大学 | Traditional Chinese medicine extract for removing cigarette and wine toxins as well as preparation method and application thereof |
| CN112704694A (en) * | 2021-01-30 | 2021-04-27 | 天赋康(温州)生物科技有限公司 | Smoking cessation oral liquid and preparation method thereof |
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