CN112704694A - Smoking cessation oral liquid and preparation method thereof - Google Patents
Smoking cessation oral liquid and preparation method thereof Download PDFInfo
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- CN112704694A CN112704694A CN202110131840.1A CN202110131840A CN112704694A CN 112704694 A CN112704694 A CN 112704694A CN 202110131840 A CN202110131840 A CN 202110131840A CN 112704694 A CN112704694 A CN 112704694A
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Abstract
The invention provides an oral liquid for smoking cessation and a preparation method thereof, relating to the field of traditional Chinese medicines. An oral liquid for quitting smoking, which comprises the following raw material components: bufo siccus, Li Wang Cao, Pearl grass, balloonflower root, aster, spina date seed, pumpkin vine, polygala root, mint and water, which can play a role in clearing away the lung-heat and benefiting the liver and relieving the symptoms of smoking addiction, can effectively help smokers to relieve the smoking addiction and has a good using effect. In addition, the invention also provides a preparation method of the smoking cessation oral liquid, which comprises the following steps: the method has simple process, is beneficial to reducing the cost, and the prepared product can effectively help smokers to quit smoking and improve the health condition of the body and has good use effect.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to smoking cessation oral liquid and a preparation method thereof.
Background
Smoking is harmful, not only is human health harmful, but also has adverse effects on society. Any organized organism, as long as it has life signs, must breathe, exhale carbon dioxide from the body, inhale oxygen from the air, and metabolize to maintain normal life activities. People who do not smoke can inhale a large amount of fresh air every day; people who smoke frequently do not enjoy the benefits of nature, and inhale toxic gas polluted by smoke instead of fresh air. The cigarette contains various toxic chemical substances, mainly tar, nicotine, carbon monoxide and the like, has damage to oral cavity, trachea and lung, can cause diseases such as chronic bronchitis, emphysema, pulmonary interstitial fibrosis and the like, can cause coronary artery vascular contraction by smoking, causes myocardial infarction to cause accelerated heart rate and aggravation of heart load, causes cardiovascular and cerebrovascular diseases, can also cause cancers such as lung cancer, esophageal cancer and the like seriously, and has huge damage.
The smoking cessation drug has the advantages that a great number of habits of smokers who want to quit smoking are provided, but once smoking is stopped or reduced, smoking addiction attacks occur, symptoms such as dysphoria, melancholy, difficulty in concentrating spirit, instability, headache and drowsiness are generated, and the symptoms are difficult to bear, so that the smokers have to start smoking again, and therefore, the development of the drug which can relieve the smoking addiction symptoms, help the smokers to quit smoking better and improve the physical health condition is particularly important.
Disclosure of Invention
The invention aims to provide an oral liquid for smoking cessation, which is mainly prepared from traditional Chinese medicines, has the effects of clearing away the lung-heat, benefiting the liver and relieving the symptoms of smoking addiction, can effectively help smokers to relieve the smoking addiction and has a good using effect.
The invention also aims to provide a preparation method of the smoking-quitting oral liquid, which has simple process and good use effect, is beneficial to reducing the cost, and the prepared product can effectively help smokers to quit smoking and improve the physical health condition.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On one hand, the embodiment of the invention provides an oral liquid for quitting smoking, which comprises the following raw material components: bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae, herba Menthae and water.
On the other hand, the embodiment of the invention provides a preparation method of an oral liquid for stopping smoking, which comprises the following steps:
raw material treatment: removing dust and impurities attached to the surface of Bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae and herba Menthae under ultrasound respectively, pulverizing, and stirring to obtain mixed medicinal powder;
and (3) preparing a finished product: adding water into the mixed medicinal powder, heating for decocting, filtering to obtain medicinal liquid, concentrating the medicinal liquid, bottling, and sterilizing to obtain the final product.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
aiming at the first aspect, the embodiment of the invention provides an oral liquid for quitting smoking, which comprises the following raw material components: bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae, herba Menthae and water.
In the above examples, the efficacy of each component was as follows:
bufo siccus: enter lung meridian to clear away heat; reducing phlegm; detoxification; killing insects; removing blood stasis; stopping bleeding. Mainly including tonsillitis, pharyngitis, acute and chronic convulsion, toothache, furuncle, toxic swelling, hemorrhoid complicated by anal fistula and skin prurigo; bite by poisonous snake; worm accumulation; blood in the abdomen; hematemesis; bleeding; blood stranguria; bleeding from the wound.
Li Wang Cao: clearing away heat, eliminating dampness, relieving swelling and pain, removing blood stasis, relieving inflammation, relieving hangover, removing liver heat, promoting gallbladder function, promoting blood circulation, and preventing cancer.
Pearl grass: calming liver, clearing away heat, inducing diuresis, removing toxic substances, and treating enteritis, dysentery, infectious hepatitis, nephritis edema, urinary tract infection, infantile malnutrition, nebula, aphtha, and undefined lump.
Balloon flower: disperse lung qi, relieve sore throat, dispel phlegm, and expel pus. Can be used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, suppuration, and pyocutaneous disease with pus formation.
Radix asteris: warm lung, descend qi, resolve phlegm and relieve cough. It is used to treat cough and asthma due to wind-cold evil, cough with pus and blood, throat impediment, and dysuria.
Wild jujube seed: tonify liver, calm heart, astringe sweat, promote fluid production. Can be used for treating vexation, insomnia, palpitation, dreaminess, asthenia, hyperhidrosis, body fluid deficiency, and thirst.
Pumpkin vine: clear lung-heat, pacify liver, harmonize stomach, dredge meridians. Mainly pulmonary tuberculosis with low fever, pain of liver and stomach qi, irregular menstruation, red eyes and pain, scald due to hot water and fire.
Polygala root: induce tranquilization and promote intelligence, dispel phlegm and relieve depression. It is indicated for palpitation, amnesia, nocturnal emission, insomnia, cough with excessive phlegm, abscess, deep-rooted carbuncle, sore and swelling.
Mint: dispelling wind, dissipating heat, removing filth, and removing toxic substance. It is used to treat wind-heat common cold, headache, conjunctival congestion, sore throat, food stagnation, flatulence, aphtha, toothache, scabies, and urticaria.
The oral liquid for quitting smoking has the effects of clearing away heat and toxic materials, removing liver heat and benefiting gallbladder through the Chinese forest frog grass, the liwang grass and the pearl grass, and can eliminate toxins accumulated in a smoker due to long-term smoking and relieve the burden of the liver of the smoker; the platycodon grandiflorum, the aster tataricus and the pumpkin vine have the effects of clearing away the lung-heat and relieving sore throat, so that the damage to the lung and the throat caused by long-term smoking of smokers is relieved and treated; the spina date seed, the polygala root and the mint have the effects of calming the heart and soothing the nerves, so that symptoms such as dysphoria and vexation generated when a smoker quits smoking are relieved, the smoker can be helped to quit smoking better, meanwhile, the effects of clearing liver and benefiting lung of the product can be assisted and enhanced, and the using effect of the product is further improved. The smoking cessation oral liquid is mainly prepared from traditional Chinese medicines, can effectively relieve and treat liver, lung and throat injuries caused by smoking, has the effects of clearing liver and benefiting lung, can relieve adverse symptoms generated during smoking cessation, helps smokers to better quit smoking, and has obvious using effect.
Aiming at the second aspect, the embodiment of the invention provides a preparation method of an oral liquid for quitting smoking, which comprises the following steps: raw material treatment and finished product preparation.
In the above embodiment, firstly, the raw material processing steps remove the dust impurities attached to the surface of the Chinese forest frog, the liwang grass, the pearl grass, the platycodon grandiflorum, the aster, the spina date seed, the pumpkin vine, the polygala tenuifolia and the mint under ultrasound, so that the purity of each raw material is improved, the influence of the impurities on the subsequent steps is avoided, the quality of the product can be improved, and the using effect of the product is further improved; then crushing into powder, stirring and mixing to prepare mixed medicinal powder, and through crushing, raw material components can be well mixed uniformly, so that the subsequent steps are convenient to carry out, and the components can be well combined and matched with each other, so that the synergistic effect is realized, and the effects of clearing liver and benefiting lung and relieving smoking addiction of the product are further promoted. Adding water into the mixed medicinal powder through the finished product preparation steps, heating for decoction, volatilizing and extracting beneficial components in the raw materials through the decoction, contributing to further improving the using effect of the product, simultaneously enabling the product to be more convenient to use and improving the using experience of the product; then the medicine residues are separated through filtration to obtain liquid medicine, the purity of the liquid medicine of the product is improved, then the liquid medicine is assembled and sterilized, and residual harmful bacteria in the product are removed through sterilization, so that the quality of the product is further improved, and the effects of clearing away the lung-heat, benefiting the liver and relieving the smoking addiction symptoms of the product are further improved. The whole preparation method has simple process, is beneficial to reducing the cost, and the prepared product can effectively help smokers to quit smoking and improve the health condition of the body and has good use effect.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The embodiment of the invention provides an oral liquid for quitting smoking, which comprises the following raw material components: bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae, herba Menthae and water.
In the above examples, the efficacy of each component was as follows:
bufo siccus: enter lung meridian to clear away heat; reducing phlegm; detoxification; killing insects; removing blood stasis; stopping bleeding. Mainly including tonsillitis, pharyngitis, acute and chronic convulsion, toothache, furuncle, toxic swelling, hemorrhoid complicated by anal fistula and skin prurigo; bite by poisonous snake; worm accumulation; blood in the abdomen; hematemesis; bleeding; blood stranguria; bleeding from the wound.
Li Wang Cao: clearing away heat, eliminating dampness, relieving swelling and pain, removing blood stasis, relieving inflammation, relieving hangover, removing liver heat, promoting gallbladder function, promoting blood circulation, and preventing cancer.
Pearl grass: calming liver, clearing away heat, inducing diuresis, removing toxic substances, and treating enteritis, dysentery, infectious hepatitis, nephritis edema, urinary tract infection, infantile malnutrition, nebula, aphtha, and undefined lump.
Balloon flower: disperse lung qi, relieve sore throat, dispel phlegm, and expel pus. Can be used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, suppuration, and pyocutaneous disease with pus formation.
Radix asteris: warm lung, descend qi, resolve phlegm and relieve cough. It is used to treat cough and asthma due to wind-cold evil, cough with pus and blood, throat impediment, and dysuria.
Wild jujube seed: tonify liver, calm heart, astringe sweat, promote fluid production. Can be used for treating vexation, insomnia, palpitation, dreaminess, asthenia, hyperhidrosis, body fluid deficiency, and thirst.
Pumpkin vine: clear lung-heat, pacify liver, harmonize stomach, dredge meridians. Mainly pulmonary tuberculosis with low fever, pain of liver and stomach qi, irregular menstruation, red eyes and pain, scald due to hot water and fire.
Polygala root: induce tranquilization and promote intelligence, dispel phlegm and relieve depression. It is indicated for palpitation, amnesia, nocturnal emission, insomnia, cough with excessive phlegm, abscess, deep-rooted carbuncle, sore and swelling.
Mint: dispelling wind, dissipating heat, removing filth, and removing toxic substance. It is used to treat wind-heat common cold, headache, conjunctival congestion, sore throat, food stagnation, flatulence, aphtha, toothache, scabies, and urticaria.
The oral liquid for quitting smoking has the effects of clearing away heat and toxic materials, removing liver heat and benefiting gallbladder through the Chinese forest frog grass, the liwang grass and the pearl grass, and can eliminate toxins accumulated in a smoker due to long-term smoking and relieve the burden of the liver of the smoker; the platycodon grandiflorum, the aster tataricus and the pumpkin vine have the effects of clearing away the lung-heat and relieving sore throat, so that the damage to the lung and the throat caused by long-term smoking of smokers is relieved and treated; the spina date seed, the polygala root and the mint have the effects of calming the heart and soothing the nerves, so that symptoms such as dysphoria and vexation generated when a smoker quits smoking are relieved, the smoker can be helped to quit smoking better, meanwhile, the effects of clearing liver and benefiting lung of the product can be assisted and enhanced, and the using effect of the product is further improved. The smoking cessation oral liquid is mainly prepared from traditional Chinese medicines, can effectively relieve and treat liver, lung and throat injuries caused by smoking, has the effects of clearing liver and benefiting lung, can relieve adverse symptoms generated during smoking cessation, helps smokers to better quit smoking, and has obvious using effect.
Further, in some embodiments of the present invention, the components in parts by weight are: 10-30 parts of Chinese forest frog grass, 15-30 parts of liwang grass, 13-30 parts of pearl grass, 15-40 parts of platycodon grandiflorum, 10-20 parts of aster, 10-30 parts of spina date seed, 15-40 parts of pumpkin vine, 10-20 parts of polygala tenuifolia, 9-20 parts of mint and 1600 parts of water as well as 2000 parts of water.
In the above embodiment, by controlling the weight parts of the raw material components, the raw material components can be better mixed with each other and matched in combination, so that the components have synergistic effect, and the effects of clearing heat and removing toxicity, and clearing liver and benefiting gallbladder of the Chinese forest frog, the Li Wang Cao and the Zhen Zhu Cao are enhanced; the effects of clearing lung and relieving sore throat of the platycodon grandiflorum, the aster tataricus and the pumpkin vine are improved; the effects of calming the heart and soothing the nerves of the spina date seeds, the polygala tenuifolia and the mint are improved, and the effects of clearing away the lung-heat and benefiting the liver of the product are further improved, so that smokers are better helped to quit smoking and the physical health condition is improved.
Further, in some embodiments of the present invention, the components in parts by weight are: 25 parts of Chinese forest frog grass, 25 parts of liwang grass, 20 parts of pearl grass, 30 parts of platycodon grandiflorum, 18 parts of aster, 20 parts of spina date seed, 30 parts of pumpkin vine, 18 parts of polygala tenuifolia, 15 parts of mint and 1800 parts of water.
In the above embodiment, by further controlling the weight parts of the raw material components, the raw material components can be further mixed with each other and matched in combination, so that the components have synergistic interaction, and the effects of clearing heat and removing toxicity, and clearing liver and benefiting gallbladder of the Chinese forest frog grass, the Li Wang Cao and the pearl grass are further enhanced; the effects of clearing lung and relieving sore throat of the platycodon grandiflorum, the aster tataricus and the pumpkin vine are improved; the effects of calming the heart and soothing the nerves of the spina date seed, the polygala root and the mint are improved, and the effects of clearing away the lung-heat and benefiting the liver of the product are further improved, so that smokers are better helped to quit smoking and the physical health condition is improved.
The embodiment of the invention also provides a preparation method of the smoking cessation oral liquid, which comprises the following steps:
raw material treatment: removing dust and impurities attached to the surface of Bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae and herba Menthae under ultrasound respectively, pulverizing, and stirring to obtain mixed medicinal powder;
and (3) preparing a finished product: adding water into the mixed medicinal powder, heating for decocting, filtering to obtain medicinal liquid, concentrating the medicinal liquid, bottling, and sterilizing to obtain the final product.
In the above embodiment, firstly, the raw material processing steps remove the dust impurities attached to the surface of the Chinese forest frog, the liwang grass, the pearl grass, the platycodon grandiflorum, the aster, the spina date seed, the pumpkin vine, the polygala tenuifolia and the mint under ultrasound, so that the purity of each raw material is improved, the influence of the impurities on the subsequent steps is avoided, the quality of the product can be improved, and the using effect of the product is further improved; then crushing into powder, stirring and mixing to prepare mixed medicinal powder, and through crushing, raw material components can be well mixed uniformly, so that the subsequent steps are convenient to carry out, and the components can be well combined and matched with each other, so that the synergistic effect is realized, and the effects of clearing liver and benefiting lung and relieving smoking addiction of the product are further promoted. Adding water into the mixed medicinal powder through the finished product preparation steps, heating for decoction, volatilizing and extracting beneficial components in the raw materials through the decoction, contributing to further improving the using effect of the product, simultaneously enabling the product to be more convenient to use and improving the using experience of the product; then the medicine residues are separated through filtration to obtain liquid medicine, the purity of the liquid medicine of the product is improved, then the liquid medicine is assembled and sterilized, and residual harmful bacteria in the product are removed through sterilization, so that the quality of the product is further improved, and the effects of clearing away the lung-heat, benefiting the liver and relieving the smoking addiction symptoms of the product are further improved. The whole preparation method has simple process, is beneficial to reducing the cost, and the prepared product can effectively help smokers to quit smoking and improve the health condition of the body and has good use effect.
Further, in some embodiments of the present invention, in the above raw material processing step, the ultrasonication is performed at a frequency of 20 to 40 KHz.
In the above embodiment, through controlling ultrasonic frequency, impurities such as dust attached to the surface of each raw material can be more effectively removed, so that the purity of each raw material is further improved, the product quality is further improved, the effects of clearing away the lung-heat and benefiting the liver, relieving the addiction to tobacco of the product are improved, and the using effect of the product is further improved.
Further, in some embodiments of the present invention, in the above raw material treatment step, the raw material components are pulverized to 60 to 100 mesh after the ultrasonic treatment.
In the embodiment, the mesh number of the crushed raw materials is controlled, so that the raw material components can be well and uniformly mixed, the raw materials can be well combined and matched, the synergistic effect is realized, the raw material components can fully exert respective beneficial effects, the effects of clearing away the lung-heat and benefiting the liver, relieving the addiction to tobacco and further improving the using effect of the product.
Further, in some embodiments of the present invention, in the step of preparing the finished product, part of water is added into the mixed medicinal powder, the temperature is raised for primary decoction, the primary decoction and the dregs are obtained after filtration, the remaining water is added into the dregs, the temperature is raised for secondary decoction, the secondary decoction is obtained after filtration, the primary decoction and the secondary decoction are combined and filtered to obtain a medicinal liquid, and the medicinal liquid is concentrated, bottled and sterilized to obtain the finished product.
In the embodiment, the decoction is carried out in two steps, part of water is firstly added into the mixed medicinal powder, the temperature is raised for carrying out primary decoction, primary decoction and medicinal residues are obtained after filtration, the rest water is then added into the medicinal residues, the temperature is raised for carrying out secondary decoction, secondary decoction is obtained after filtration, the primary decoction and the secondary decoction are combined and filtered to obtain medicinal liquid, so that beneficial components in each raw material component can be more fully extracted into the medicinal liquid, and the quality of the product is improved; and then the obtained liquid medicine is further concentrated, so that the using effect of the product can be further improved, and the beneficial effects of clearing lung and benefiting liver and relieving smoking addiction of the product are enhanced.
Further, in some embodiments of the present invention, in the step of preparing the final product, the temperature is increased to boiling and then decreased to 60-80 ℃ for decoction when the first decoction and the second decoction are performed.
In the embodiment, the beneficial components in the raw materials can be more effectively extracted into the liquid medicine by heating to boiling and then cooling to 60-80 ℃ for primary decoction and secondary decoction, and meanwhile, the beneficial components in the raw materials can be prevented from being damaged or incompletely extracted due to improper decoction temperature, so that the quality of the product can be further improved, and the using effect of the product can be further improved.
Further, in some embodiments of the present invention, in the step of preparing the finished product, the weight ratio of the primary decoction to the added part of water is 2: 5; the weight ratio of the secondary decoction to the rest water is 1: 4; the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4.
In the above embodiment, by controlling the decoction amount after the primary decoction and the secondary decoction and the concentrated decoction amount, the quality of the product can be further improved, the effects of clearing away the lung-heat and benefiting the liver and relieving the addiction to tobacco of the product can be further enhanced, and the using effect of the product can be comprehensively improved.
Further, in some embodiments of the present invention, the step of preparing the final product is performed by sterilizing the product at 110-130 ℃ for 3-8 s.
In the embodiment, the sterilization temperature and the sterilization time are controlled, so that residual harmful bacteria in the product can be effectively eliminated, and beneficial ingredients in the product are prevented from being damaged or insufficiently sterilized due to improper sterilization temperature or sterilization time, the quality of the product is further improved, and the using effect of the product is further improved.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: removing dust and impurities attached to the surface of 5g of Chinese forest frog grass, 10g of Li Wang grass, 10g of pearl grass, 10g of platycodon grandiflorum, 5g of aster, 5g of spina date seed, 10g of pumpkin vine, 5g of polygala tenuifolia and 5g of mint by ultrasound at the frequency of 20KHz respectively, then crushing to 100 meshes, and stirring and mixing to obtain mixed medicinal powder;
and (3) preparing a finished product: taking 1200g of water, firstly adding 600g of water into the mixed medicinal powder, heating to boil, then cooling to 60 ℃ for primary decoction, and filtering to obtain primary decoction and dregs of a decoction, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs of a decoction, heating to boil, cooling to 60 ℃ for secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 110 deg.C for 8s to obtain the final product.
Example 2
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: removing dust and impurities attached to the surface of Bufo siccus 35g, Liwangcao 35g, Phyllanthus urinaria 35g, Platycodon grandiflorum 45g, Aster 25g, Zizyphi Spinosae semen 35g, Cucurbita pepo 45g, Polygala tenuifolia 25g and Mentha haplocalyx 25g by ultrasonic at the frequency of 40KHz, pulverizing to 60 mesh, and mixing to obtain mixed powder;
and (3) preparing a finished product: taking 2200g of water, firstly adding 1100g of water into the mixed medicinal powder, heating to boil, then cooling to 80 ℃ for primary decoction, and filtering to obtain primary decoction and dregs of a decoction, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs of a decoction, heating to boil, cooling to 80 ℃ for secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 130 deg.C for 3s to obtain the final product.
Example 3
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: removing dust and impurities attached to the surface of 10g of Chinese forest frog grass, 15g of liwang grass, 13g of pearl grass, 15g of platycodon grandiflorum, 10g of aster, 10g of spina date seed, 15g of pumpkin vine, 10g of polygala tenuifolia and 9g of mint by ultrasonic treatment at the frequency of 28KHz, then crushing to 80 meshes, and stirring and mixing to obtain mixed medicinal powder;
and (3) preparing a finished product: taking 1600g of water, firstly adding 800g of water into the mixed medicinal powder, heating to boil, then cooling to 70 ℃ for primary decoction, and filtering to obtain primary decoction and dregs of a decoction, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs of a decoction, heating to boil, cooling to 60-80 ℃, carrying out secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 120 deg.C for 5s to obtain the final product.
Example 4
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: removing dust and impurities attached to the surface of 30g of Chinese forest frog grass, 30g of Li Wang grass, 30g of pearl grass, 40g of platycodon grandiflorum, 20g of aster, 30g of spina date seed, 40g of pumpkin vine, 20g of polygala tenuifolia and 20g of mint by ultrasonic treatment at the frequency of 28KHz, then crushing to 70 meshes, and stirring and mixing to obtain mixed medicinal powder;
and (3) preparing a finished product: adding 1000g of water into 2000g of water, heating to boil, cooling to 65 ℃ for primary decoction, and filtering to obtain primary decoction and dregs of a decoction, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs of a decoction, heating to boil, cooling to 65 ℃ for secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 115 deg.C for 7s to obtain the final product.
Example 5
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: removing dust and impurities attached to the surface of 20g of Chinese forest frog grass, 20g of Li Wang grass, 20g of pearl grass, 30g of platycodon grandiflorum, 15g of aster, 20g of spina date seed, 30g of pumpkin vine, 15g of polygala tenuifolia and 15g of mint by ultrasonic treatment at the frequency of 28KHz, then crushing to 90 meshes, and stirring and mixing to obtain mixed medicinal powder;
and (3) preparing a finished product: taking 1800g of water, firstly adding 900g of water into the mixed medicinal powder, heating to boil, then cooling to 75 ℃ for primary decoction, and filtering to obtain primary decoction and dregs of a decoction, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs, heating to boil, cooling to 75 ℃ for secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 125 deg.C for 4s to obtain the final product.
Example 6
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: ultrasonically removing dust impurities attached to the surface of 12g of Chinese forest frog grass, 18g of liwang grass, 15g of pearl grass, 20g of platycodon grandiflorum, 12g of aster, 12g of spina date seed, 18g of pumpkin vine, 12g of polygala tenuifolia and 15g of mint at the frequency of 28KHz respectively, then crushing to 100 meshes, and stirring and mixing to obtain mixed medicinal powder;
and (3) preparing a finished product: adding 900g of water into 1900g of water, heating to boil, cooling to 75 ℃ for primary decoction, and filtering to obtain primary decoction and dregs, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs, heating to boil, cooling to 75 ℃ for secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 120 deg.C for 6s to obtain the final product.
Example 7
The embodiment provides an oral liquid for smoking cessation, which is prepared by the following method:
raw material treatment: removing dust and impurities attached to the surface of 25g of Chinese forest frog grass, 25g of liwang grass, 20g of pearl grass, 30g of platycodon grandiflorum, 18g of aster, 20g of spina date seed, 30g of pumpkin vine, 18g of polygala tenuifolia and 15g of mint by ultrasonic treatment at the frequency of 28KHz, then crushing to 80 meshes, and stirring and mixing to obtain mixed medicinal powder;
and (3) preparing a finished product: taking 1800g of water, firstly adding 1000g of water into the mixed medicinal powder, heating to boil, then cooling to 75 ℃ for primary decoction, and filtering to obtain primary decoction and dregs of a decoction, wherein the weight ratio of the primary decoction to the added part of water is 2: 5; adding the rest water into the dregs, heating to boil, cooling to 75 ℃ for secondary decoction, and filtering to obtain secondary decoction, wherein the weight ratio of the secondary decoction to the added rest water is 1: 4; mixing the primary decoction and the secondary decoction, filtering to obtain liquid medicine, concentrating the liquid medicine, wherein the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4; bottling, and sterilizing at 120 deg.C for 6s to obtain the final product.
Test examples
The smoking-quitting oral liquid provided by the embodiment 7 of the invention is delivered to a Wenzhou city quality technical supervision and detection institute at 5-22 days in 2020, and the quality detection is carried out according to the national standard GB7101-2015, and the detection result is shown in Table 1:
TABLE 1
150 smokers who smoking all the year round and have smoking addiction and hope to relieve the smoking addiction use the smoking-quitting oral liquid provided by the invention for 30 days, the smoking-quitting effect and the physical health condition are observed, and the observation results are shown in table 2:
TABLE 2
| Age of cigarette | Number of people | Effective number of people giving up smoking | The number of people who fail to stop smoking | High efficiency |
| 1-2 years old | 21 | 21 | 0 | 100％ |
| 2-5 years old | 22 | 22 | 0 | 100％ |
| 5-10 years old | 75 | 72 | 3 | 96％ |
| For more than 10 years | 32 | 28 | 4 | 87.50％ |
The following are some typical cases:
li Shi, male, 28 years old, 1 year old, apparently felt shortness of breath and chest distress during exercise or physical work, and tried to quit smoking but failed. The smoking cessation oral liquid provided by the invention is used for 30 days, smoking is prohibited during the period, obvious smoking addiction attack symptoms are not sensed, smoking cessation is smoothly performed after 30 days, the symptoms of short breath and chest distress do not appear at present, and the smoking cessation effect is obvious.
Zhao, male, age 32 years old, with tobacco age 5 years, has pharyngitis and has tried to quit smoking, but has not succeeded because the craving for tobacco has been out of tolerance. The smoking cessation oral liquid provided by the invention is continuously used for 30 days, smoking is prohibited in the period, other obvious symptoms are not caused except that the user feels vexation occasionally, the smoking cessation is successful after 30 days, the pharyngitis symptom is also obviously improved, and the smoking cessation effect is obvious.
Wu-chi, male age 42, age 15 years old, has large smoking amount, large tobacco addiction, perennial cough, excessive phlegm, dizziness and difficulty in concentration. The smoking cessation oral liquid provided by the invention is continuously used for 30 days, smoking is prohibited during the period, dysphoric and sleepy smoking addiction symptoms occasionally occur, but the smoking cessation oral liquid is in a tolerable range, the smoking cessation is successful after 30 days, the cough frequency is obviously reduced, dizziness symptoms do not occur, the attention can be focused for a long time, the physical health condition is obviously improved, and the smoking cessation effect is obvious.
Wangzhi, women, age 52 years old, age 35 years old, smoking amount is large, cough and sputum are too much all the year round, smoking cessation has been tried but not succeeded. By continuously using the smoking cessation oral liquid provided by the invention for 30 days, the symptoms of cough and excessive phlegm are obviously improved, the smoking addiction is quitted, and the physical health condition is obviously improved.
Xie somebody, male, 51 years old, 38 years old, large smoking amount, perennial cough with excessive phlegm, intense cough after physical work and exercise, and layered attempt to quit smoking but unsuccessful. The smoking cessation oral liquid provided by the invention is continuously used for 30 days, the symptoms of cough and excessive phlegm are obviously improved, the physical quality is obviously enhanced, the cough is avoided after physical work and movement, the smoking addiction is quitted, and the effect is obvious.
Through the tests, the smoking cessation oral liquid provided by the invention meets the national quality standard, can effectively help smokers to abstain from smoking, improves the physical health condition of the smokers, and has high product quality and good use effect.
In summary, according to the oral liquid for smoking cessation and the preparation method thereof provided by the embodiment of the invention, the oral liquid has the effects of clearing away heat and toxic materials, clearing liver and benefiting gallbladder through the Chinese forest frog grass, the Li Wang Cao and the pearl grass, and can eliminate toxins accumulated in a body of a smoker due to long-term smoking and relieve the liver burden of the smoker; the platycodon grandiflorum, the aster tataricus and the pumpkin vine have the effects of clearing away the lung-heat and relieving sore throat, so that the damage to the lung and the throat caused by long-term smoking of smokers is relieved and treated; the spina date seed, the polygala root and the mint have the effects of calming the heart and soothing the nerves, so that symptoms such as dysphoria and vexation generated when a smoker quits smoking are relieved, the smoker can be helped to quit smoking better, meanwhile, the effects of clearing liver and benefiting lung of the product can be assisted and enhanced, and the using effect of the product is further improved. The smoking cessation oral liquid is mainly prepared from traditional Chinese medicines, can effectively relieve and treat liver, lung and throat injuries caused by smoking, has the effects of clearing liver and benefiting lung, can relieve adverse symptoms generated during smoking cessation, helps smokers to better quit smoking, and has obvious using effect.
According to the preparation method, firstly, the oviductus ranae, the liwang grass, the phyllanthus urinaria, the platycodon grandiflorum, the aster, the spina date seed, the pumpkin vine, the polygala tenuifolia and the mint are subjected to ultrasonic treatment to remove dust impurities attached to the surfaces of the oviductus ranae, the radix asteris, the spina date seed, the pumpkin vine, the polygala tenuifolia and the mint, so that the purity of each raw material is improved, the influence of the impurities on the subsequent steps is avoided, the quality of; then crushing into powder, stirring and mixing to prepare mixed medicinal powder, and through crushing, raw material components can be well mixed uniformly, so that the subsequent steps are convenient to carry out, and the components can be well combined and matched with each other, so that the synergistic effect is realized, and the effects of clearing liver and benefiting lung and relieving smoking addiction of the product are further promoted. Adding water into the mixed medicinal powder through the finished product preparation steps, heating for decoction, volatilizing and extracting beneficial components in the raw materials through the decoction, contributing to further improving the using effect of the product, simultaneously enabling the product to be more convenient to use and improving the using experience of the product; then the medicine residues are separated through filtration to obtain liquid medicine, the purity of the liquid medicine of the product is improved, then the liquid medicine is assembled and sterilized, and residual harmful bacteria in the product are removed through sterilization, so that the quality of the product is further improved, and the effects of clearing away the lung-heat, benefiting the liver and relieving the smoking addiction symptoms of the product are further improved. The whole preparation method has simple process, is beneficial to reducing the cost, and the prepared product can effectively help smokers to quit smoking and improve the health condition of the body and has good use effect.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Claims (10)
1. The smoking cessation oral liquid is characterized by comprising the following raw material components: bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae, herba Menthae and water.
2. The oral liquid for stopping smoking according to claim 1, wherein the weight parts of the components are respectively as follows: 10-30 parts of Chinese forest frog grass, 15-30 parts of liwang grass, 13-30 parts of pearl grass, 15-40 parts of platycodon grandiflorum, 10-20 parts of aster, 10-30 parts of spina date seed, 15-40 parts of pumpkin vine, 10-20 parts of polygala tenuifolia, 9-20 parts of mint and 1600 parts of water as well as 2000 parts of water.
3. The oral liquid for stopping smoking according to claim 1, wherein the weight parts of the components are respectively as follows: 25 parts of Chinese forest frog grass, 25 parts of liwang grass, 20 parts of pearl grass, 30 parts of platycodon grandiflorum, 18 parts of aster, 20 parts of spina date seed, 30 parts of pumpkin vine, 18 parts of polygala tenuifolia, 15 parts of mint and 1800 parts of water.
4. A process for preparing an oral liquid for smoking cessation according to any one of claims 1 to 3, comprising the steps of:
raw material treatment: removing dust and impurities attached to the surface of Bufo siccus, Li Wang Cao, herba Phyllanthi Urinariae, radix Platycodi, radix Asteris, semen Ziziphi Spinosae, caulis Cucurbitae, cortex et radix Polygalae and herba Menthae under ultrasound respectively, pulverizing, and stirring to obtain mixed medicinal powder;
and (3) preparing a finished product: adding water into the mixed medicinal powder, heating for decocting, filtering to obtain medicinal liquid, concentrating the medicinal liquid, bottling, and sterilizing to obtain the final product.
5. The method for preparing oral liquid for stopping smoking according to claim 4, wherein the raw material treatment step comprises performing ultrasound at 20-40KHz frequency.
6. The method for preparing oral liquid for stopping smoking according to claim 4, wherein in the step of processing raw materials, the raw material components are pulverized to 60-100 mesh after ultrasonic treatment.
7. The preparation method of the oral liquid for stopping smoking according to claim 4, wherein in the step of preparing the finished product, part of water is added into the mixed medicinal powder, the mixture is heated for primary decoction, the mixture is filtered to obtain primary decoction and medicinal residue, the rest water is added into the medicinal residue, the mixture is heated for secondary decoction, the mixture is filtered to obtain secondary decoction, the primary decoction and the secondary decoction are combined and filtered to obtain medicinal liquid, and the medicinal liquid is concentrated, bottled and sterilized to obtain the finished product.
8. The method for preparing smoking cessation oral liquid according to claim 7, wherein in the step of preparing the finished product, the temperature is raised to boiling and then the temperature is lowered to 60-80 ℃ for decoction when the primary decoction and the secondary decoction are carried out.
9. The method for preparing oral liquid for stopping smoking according to claim 8, wherein in the step of preparing the finished product, the weight ratio of the primary decoction to the added part of water is 2: 5; the weight ratio of the secondary decoction to the rest water is 1: 4; the weight ratio of the concentrated liquid medicine to the liquid medicine before concentration is 1: 4.
10. The method for preparing oral liquid for stopping smoking as claimed in claim 4, wherein the step of preparing the final product comprises sterilizing at 110-130 deg.C for 3-8 s.
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| CN202110131840.1A CN112704694A (en) | 2021-01-30 | 2021-01-30 | Smoking cessation oral liquid and preparation method thereof |
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Effective date of registration: 20240116 Address after: Room B1-3617, Building 3, No. 20 Yong'an Road, Shilong Economic Development Zone, Mentougou District, Beijing, 102300 Applicant after: Huaxia Code (Beijing) Institute of Pharmaceutical Sciences Address before: 325800, 4th Floor, Building 6, Marinated Food Small and Micro Park (Phase II), Lingxi Town, Cangnan County, Wenzhou City, Zhejiang Province Applicant before: Tiantiankang (Wenzhou) Biotechnology Co.,Ltd. |
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Application publication date: 20210427 |