CN105796898A - 一种治疗乳腺结核的中药组合物 - Google Patents

一种治疗乳腺结核的中药组合物 Download PDF

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CN105796898A
CN105796898A CN201610222926.4A CN201610222926A CN105796898A CN 105796898 A CN105796898 A CN 105796898A CN 201610222926 A CN201610222926 A CN 201610222926A CN 105796898 A CN105796898 A CN 105796898A
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姜丽莎
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Abstract

本发明涉及一种治疗乳腺结核的中药组合物，其中药原料及重量份配比为：蒲公英10‑30份、穿山甲5‑25份、元宝草5‑25份、白蔹5‑20份、萱草根5‑25份、紫花地丁5‑25份、白蒺藜5‑25份、大九节铃5‑20份、海藻5‑25份、饭团根5‑25份、蒲葵子5‑25份、响铃草5‑25份、黄精5‑25份、急性子5‑20份、山慈菇5‑25份、木芙蓉5‑25份、南蛇藤根5‑25份、青皮5‑20份、肉苁蓉5‑25份、瓦楞子5‑25份、三果木皮5‑20份、玄参5‑25份、寻骨风5‑25份、算盘子根5‑25份。本发明的中药组合物具有疏肝解郁、滋肾润肺、行气活血、软坚消痰、泻火解毒、消肿散结的功效，其治疗乳腺结核疗效显著，作用可靠。

Description

一种治疗 乳腺结核 的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗乳腺结核的中药组合物。
背景技术
乳腺结核是一种多继发于肺结核、肠结核或肠系膜淋巴结构的疾病，经血行传播至乳房所引起的结核，临床较少见。常见于 20 ～ 40 岁的妇女，病程缓慢，初期时乳房内有一个或数个结节，无疼痛或触痛，与周围组织分界不清，常有皮肤粘连，同侧腋窝淋巴结可以肿大，脓块软化后形成冷脓疡，可向皮肤穿出形成瘘管或窦道，排出有干酪样碎屑的稀薄脓液，少数病人的肿块经纤维化而变成硬块，使乳房外形改变和乳头内陷，因此与乳腺癌难以区别。患者侧腋窝淋巴结可肿大，可伴有低热，盗汗，血沉快。由于结核杆菌的耐药强，抗结核药物的副作用大，乳腺结核的治疗中存在病程长、难治愈、易复发的不足，一般的西医药疗法，很难达到预期的效果。
祖国医学认为乳腺结核多由素体肺肾阴虚，阴虚火旺，灼津为痰，痰火凝结而成；或由情志内伤，肝郁化火，耗伤阴液，痰凝气郁而成；或由肺痨、瘰疬、肾痨等病继发所致。
根据中医理论，针对乳腺结核的发病机理，采用疏肝解郁、滋肾润肺、行气活血、软坚消痰、泻火解毒、消肿散结的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中治疗乳腺结核存在病程长、难治愈、易复发的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗乳腺结核的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗乳腺结核的中药组合物，其特征在于：其中药原料及重量份配比为：蒲公英10-30份、穿山甲5-25份、元宝草5-25份、白蔹5-20份、萱草根5-25份、紫花地丁5-25份、白蒺藜5-25份、大九节铃5-20份、海藻5-25份、饭团根5-25份、蒲葵子5-25份、响铃草5-25份、黄精5-25份、急性子5-20份、山慈菇5-25份、木芙蓉5-25份、南蛇藤根5-25份、青皮5-20份、肉苁蓉5-25份、瓦楞子5-25份、三果木皮5-20份、玄参5-25份、寻骨风5-25份、算盘子根5-25份。
本发明的优选技术方案是：一种治疗乳腺结核的中药组合物，其特征在于：其中药原料及重量份配比为：蒲公英20份、穿山甲15份、元宝草15份、白蔹10份、萱草根15份、紫花地丁15份、白蒺藜15份、大九节铃10份、海藻15份、饭团根15份、蒲葵子15份、响铃草15份、黄精15份、急性子10份、山慈菇15份、木芙蓉15份、南蛇藤根15份、青皮10份、肉苁蓉15份、瓦楞子15份、三果木皮10份、玄参15份、寻骨风15份、算盘子根15份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：蒲公英具有清热解毒、消肿散结、利尿通淋的功效；穿山甲具有活血通络、消肿排脓、祛风止痛、通乳的功效；元宝草具有清热解毒、通经活络、凉血止血的功效；白蔹具有清热解毒、消痈散结的功效；萱草根具有清热利湿 、凉血止血 、解毒消肿的功效；紫花地丁具有清热解毒、活血消肿的功效；白蒺藜具有疏肝解郁、祛风明目的功效；大九节铃具有活血止痛、解毒敛疮的功效；海藻具有软坚消痰、利水退肿的功效；饭团根具有行气活血、散瘀止痛的功效；蒲葵子具有活血化瘀、软坚散结的功效；响铃草具有滋肾养肝、止咳平喘、利湿解毒的功效；黄精具有滋肾润肺、补脾益气、养阴生津的功效；急性子具有行瘀降气、软坚散结的功效；山慈菇具有清热解毒、化痰散结的功效；木芙蓉具有清热解毒、消肿排脓、凉血止血的功效；南蛇藤根具有祛风除湿、活血通经、消肿解毒的功效；青皮具有疏肝破气、消积化滞的功效；肉苁蓉具有补肾阳、益精血、润肠通便的功效；瓦楞子具有消痰化瘀、软坚散结、制酸止痛的功效；三果木皮具有补气活血、解毒敛疮的功效；玄参具有凉血滋阴、泻火解毒的功效；寻骨风具有祛风除湿、活血通络、止痛的功效；算盘子根具有清热利湿、活血解毒的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏疏肝解郁、滋肾润肺、行气活血、软坚消痰、泻火解毒、消肿散结的功效，对乳腺结核的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达95%，治愈率76.5%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗乳腺结核的中药组合物，其中药原料及重量配比为：蒲公英20g、穿山甲15g、元宝草15g、白蔹10g、萱草根15g、紫花地丁15g、白蒺藜15g、大九节铃10g、海藻15g、饭团根15g、蒲葵子15g、响铃草15g、黄精15g、急性子10g、山慈菇15g、木芙蓉15 g、南蛇藤根15g、青皮10g、肉苁蓉15g、瓦楞子15g、三果木皮10g、玄参15g、寻骨风15g、算盘子根15g。
实施例2
一种治疗乳腺结核的中药组合物，其中药原料及重量配比为：蒲公英15g、穿山甲25g、元宝草10g、白蔹20g、萱草根5g、紫花地丁25g、白蒺藜10g、大九节铃20g、海藻5g、饭团根25g、蒲葵子10g、响铃草20g、黄精5g、急性子15g、山慈菇10g、木芙蓉20g、南蛇藤根5g、青皮15g、肉苁蓉10g、瓦楞子20g、三果木皮5g、玄参25g、寻骨风10g、算盘子根20g。
实施例3
一种治疗乳腺结核的中药组合物，其中药原料及重量配比为：蒲公英25g、穿山甲10g、元宝草25g、白蔹5g、萱草根20g、紫花地丁10g、白蒺藜25g、大九节铃5g、海藻20g、饭团根10g、蒲葵子25g、响铃草5g、黄精20g、急性子12g、山慈菇25g、木芙蓉5g、南蛇藤根20g、青皮12g、肉苁蓉25g、瓦楞子5g、三果木皮20g、玄参10g、寻骨风25g、算盘子根5g。
实施例4
一种治疗乳腺结核的中药组合物，其中药原料及重量配比为：蒲公英10g、穿山甲20g、元宝草5g、白蔹15g、萱草根10g、紫花地丁20g、白蒺藜5g、大九节铃15g、海藻10g、饭团根20g、蒲葵子5g、响铃草25g、黄精10g、急性子20g、山慈菇5g、木芙蓉25g、南蛇藤根10g、青皮20g、肉苁蓉5g、瓦楞子25g、三果木皮12g、玄参20g、寻骨风5g、算盘子根25g。
实施例5
一种治疗乳腺结核的中药组合物，其中药原料及重量配比为：蒲公英30g、穿山甲5g、元宝草20g、白蔹12g、萱草根25g、紫花地丁5g、白蒺藜20g、大九节铃12g、海藻25g、饭团根5g、蒲葵子20g、响铃草10g、黄精25g、急性子5g、山慈菇20g、木芙蓉10g、南蛇藤根25g、青皮5g、肉苁蓉20g、瓦楞子10g、三果木皮15g、玄参5g、寻骨风20g、算盘子根10g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗乳腺结核的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例60例，年龄20～45岁。
二、诊断依据：
1、发病缓慢，乳房偏上方有一个或数个结块，皮色不变，推之可动；
2、化脓时结块增大，与表皮粘连，色转暗红，有轻微波动感，轻度触痛；
3、溃后脓出稀薄，并夹有败絮样物，可形成漏管，愈合缓慢，有时可串延胸胁、腋下；
4、本病常发生在20～40岁已婚素体虚弱的妇女。病久可伴有潮热，盗汗，消瘦，颧红等症状；
5、血沉增快，脓液涂片可找到结核杆菌，脓液培养有结核杆菌生长。必要时做病理组织活检。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。六天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
1、治愈：临床症状消失，乳房肿块消失，溃疡及窦道愈合，一年内未复发者；
2、有效：临床症状明显好转，肿块明显缩小，或者溃疡及窦道基本或接近愈合；
3、无效：肿块无任何明显变化，或者溃疡、窦道无愈合。
五、治疗效果：该临床观察病例中，服药2-5个疗程，痊愈46例，随访未见复发；有效11例，无效3例。治疗期间未发生毒副作用。
六、典型病例：
病例1：
赵某，女，27岁。1个月前，患者洗澡时，发现左侧乳房内侧有肿块，约蛋黄大小，无疼痛，近几日，肿块无明显诱因出现阵发性胀痛，检查时，发现左侧乳房内侧上象限有一约 3.8cm×5.2cm 的肿块，质地硬，边界不清，肿块表面皮肤有小面积破溃，切取部分肿块做病理检查发现有结核结节和大片干酪样坏死，诊断为：乳腺结核。服用本发明中药组合物制备的药剂2个疗程，疼痛消失，破溃开始愈合，肿块有所变小，继续服用3个疗程，肿块消失，溃疡愈合，治愈。随访1年无复发。
病例2：
汤某，27岁。1个月前右侧乳房偏上方出现数个结块，皮色不变，推之不移动，硬而不坚，微痛，伴潮热，盗汗，消瘦。诊见：舌淡红，苔薄腻，脉弦。诊断为：乳腺结核。服用本发明中药组合物制备的药剂2个疗程，肿块缩小，潮热，盗汗等症消失；继续服用2个疗程，肿块消失，治愈。

Claims (2)

1.一种治疗乳腺结核的中药组合物，其特征在于：其中药原料及重量份配比为：蒲公英10-30份、穿山甲5-25份、元宝草5-25份、白蔹5-20份、萱草根5-25份、紫花地丁5-25份、白蒺藜5-25份、大九节铃5-20份、海藻5-25份、饭团根5-25份、蒲葵子5-25份、响铃草5-25份、黄精5-25份、急性子5-20份、山慈菇5-25份、木芙蓉5-25份、南蛇藤根5-25份、青皮5-20份、肉苁蓉5-25份、瓦楞子5-25份、三果木皮5-20份、玄参5-25份、寻骨风5-25份、算盘子根5-25份。
2.根据权利要求1所述一种治疗乳腺结核的中药组合物，其特征在于：其中药原料及重量份配比为：蒲公英20份、穿山甲15份、元宝草15份、白蔹10份、萱草根15份、紫花地丁15份、白蒺藜15份、大九节铃10份、海藻15份、饭团根15份、蒲葵子15份、响铃草15份、黄精15份、急性子10份、山慈菇15份、木芙蓉15份、南蛇藤根15份、青皮10份、肉苁蓉15份、瓦楞子15份、三果木皮10份、玄参15份、寻骨风15份、算盘子根15份。
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Citations (1)

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Publication number Priority date Publication date Assignee Title
CN104127793A (zh) * 2014-07-23 2014-11-05 田娟 一种治疗乳腺结核的中药组合物

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CN104127793A (zh) * 2014-07-23 2014-11-05 田娟 一种治疗乳腺结核的中药组合物

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