CN105770753A - 一种治疗宫外孕的中药组合物 - Google Patents

一种治疗宫外孕的中药组合物 Download PDF

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CN105770753A
CN105770753A CN201610254347.8A CN201610254347A CN105770753A CN 105770753 A CN105770753 A CN 105770753A CN 201610254347 A CN201610254347 A CN 201610254347A CN 105770753 A CN105770753 A CN 105770753A
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张昌莲
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Abstract

本发明公开了一种治疗宫外孕的中药组合物,其中药原料及重量份配比为:丹参10‑30份,锁阳10‑20份,莪术5‑15份,紫草10‑20份,红藤10‑20份,麦冬10‑20份,陈皮5‑15份,水红花子10‑20份,菟丝子10‑20份,五灵脂5‑15份,蒲公英10‑20份,牡丹皮10‑20份,红花5‑15份,薏苡仁10‑20份,白花蛇舌草10‑20份,紫石英10‑20份,竹茹5‑15份,大黄10‑20份,昆布10‑20份,天花粉10‑20份,甘草5‑15份。本发明中药组合物具有活血调经、祛瘀止痛、补血益气、舒经通络的功效,其治疗宫外孕疗效显著,作用可靠。

Description

一种治疗宫外孕的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗宫外孕的中药组合物。
背景技术
宫外孕又称异位妊娠,是孕卵在子宫腔外着床发育的异常妊娠过程,以输卵管妊娠最常见。病因常由于输卵管管腔或周围的炎症,引起管腔通畅不佳,阻碍孕卵正常运行,使之在输卵管内停留、着床、发育,导致输卵管妊娠流产或破裂。在流产或破裂前往往无明显症状,也可有停经、腹痛、少量阴道出血。破裂后表现为急性剧烈腹痛,反复发作,阴道出血,以至休克。目前,临床上治疗宫外孕通常实施手术治疗,但其输卵管大多难以保留;而甲氨蝶呤等抗生素类药物治疗适用于早期输卵管妊娠、要求保存生育能力的年轻患者,但长期服用有副作用,对身体会造成很大的伤害。
中医认为,宫外孕的发生是由于少腹宿有瘀滞,使气血运行受阻,冲任不畅,导致胎孕位置异常。
根据中医理论,针对宫外孕的发病机理,以活血祛瘀、行气止痛为治则,进行辩证配伍组方,以达到标本兼治的目的。
发明内容
为了克服现有技术中抗生素类药物治疗宫外孕存在副作用大的不足,本发明提供一种配制方便、药源广、成本低、疗效显著、作用可靠、无副作用的治疗宫外孕的中药组合物。
本发明解决其技术问题所采用的技术方案是:一种治疗宫外孕的中药组合物,其特征在于:其中药原料及重量份配比为:丹参10-30份,锁阳10-20份,莪术5-15份,紫草10-20份,红藤10-20份,麦冬10-20份,陈皮5-15份,水红花子10-20份,菟丝子10-20份,五灵脂5-15份,蒲公英10-20份,牡丹皮10-20份,红花5-15份,薏苡仁10-20份,白花蛇舌草10-20份,紫石英10-20份,竹茹5-15份,大黄10-20份,昆布10-20份,天花粉10-20份,甘草5-15份。
本发明的优选技术方案是:一种治疗宫外孕的中药组合物,其特征在于:其中药原料及重量份配比为:丹参20份,锁阳15份,莪术10份,紫草15份,红藤15份,麦冬15份,陈皮10份,水红花子15份,菟丝子15份,五灵脂10份,蒲公英15份,牡丹皮15份,红花10份,薏苡仁15份,白花蛇舌草15份,紫石英15份,竹茹10份,大黄15份,昆布15份,天花粉15份,甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:丹参具有活血调经、祛瘀止痛、凉血消痈、清心除烦、养血安神的功效;锁阳具有补肾阳、益精血、润肠通便的功效;莪术具有行气破血、消积止痛的功效;紫草具有清热凉血、活血化瘀、解毒透疹的功效;红藤具有清热解毒、活血通络、败毒散瘀、祛风杀虫的功效;麦冬具有养阴生津、润肺清心的功效;陈皮具有理气健脾、调中利水、燥湿化痰的功效;水红花子具有活血消积、健脾利湿、清热解毒、明目的功效;菟丝子具有补肾益精、养肝健脾的功效;五灵脂具有活血止痛、化瘀止血的功效;蒲公英具有清热解毒、消肿散结、利尿通淋的功效;牡丹皮具有清热凉血、活血散瘀的功效;红花具有活血通经、散瘀止痛的功效;薏苡仁具有利水消肿、健脾去湿、舒筋除痹、清热排脓的功效;白花蛇舌草具有清热解毒、利尿消肿、活血止痛的功效;紫石英具有镇心安神、降逆气、暖子宫的功效;竹茹具有清热化痰、除烦止呕的功效;大黄具有泻火消积、清热解毒、凉血止血、祛瘀止咳的功效;昆布具有软坚散结、消痰利水的功效;天花粉具有生津止渴、降火润燥、排脓消肿的功效;甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏活血调经、祛瘀止痛、补血益气、舒经通络之功效,对宫外孕达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。其遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,作用可靠,药性平和,未出现毒副作用,总有效率84%,治愈率达60.3%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例 1
一种治疗宫外孕的中药组合物,其中药原料及重量配比为:丹参20g,锁阳15g,莪术10g,紫草15g,红藤15g,麦冬15g,陈皮10g,水红花子15g,菟丝子15g,五灵脂10g,蒲公英15g,牡丹皮15g,红花10g,薏苡仁15g,白花蛇舌草15g,紫石英15g,竹茹10g,大黄15g,昆布15g,天花粉15g,甘草10g。
实施例 2
一种治疗宫外孕的中药组合物,其中药原料及重量配比为:丹参30g,锁阳10g,莪术15g,紫草10g,红藤20g,麦冬10g,陈皮15g,水红花子10g,菟丝子20g,五灵脂5g,蒲公英20g,牡丹皮10g,红花15g,薏苡仁10g,白花蛇舌草20g,紫石英10g,竹茹15g,大黄10g,昆布20g,天花粉10g,甘草15g。
实施例 3
一种治疗宫外孕的中药组合物,其中药原料及重量配比为:丹参10g,锁阳20g,莪术5g,紫草20g,红藤10g,麦冬20g,陈皮5g,水红花子20g,菟丝子10g,五灵脂15g,蒲公英10g,牡丹皮20g,红花5g,薏苡仁20g,白花蛇舌草10g,紫石英20g,竹茹5g,大黄20g,昆布10g,天花粉20g,甘草5g。
实施例 4
一种治疗宫外孕的中药组合物,其中药原料及重量配比为:丹参23g,锁阳12g,莪术13g,紫草12g,红藤17g,麦冬12g,陈皮13g,水红花子12g,菟丝子18g,五灵脂7g,蒲公英18g,牡丹皮12g,红花13g,薏苡仁12g,白花蛇舌草18g,紫石英12g,竹茹13g,大黄12g,昆布18g,天花粉12g,甘草13g。
实施例 5
一种治疗宫外孕的中药组合物,其中药原料及重量配比为:丹参17g,锁阳17g,莪术7g,紫草18g,红藤12g,麦冬17g,陈皮7g,水红花子18g,菟丝子12g,五灵脂13g,蒲公英12g,牡丹皮17g,红花7g,薏苡仁18g,白花蛇舌草12g,紫石英17g,竹茹7g,大黄18g,昆布12g,天花粉17g,甘草7g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约6厘米,进行第一次煎煮,未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二次煎煮,加水没过药面约6厘米,水沸后煎煮15~20分钟。两次煎煮去渣取汁,合并。
本发明以实施例1所给出的一种治疗宫外孕的中药组合物,做临床疗效总结如下:
一、一般性资料:本发明中药组合物应用于临床观察病例女58例,年龄20~37岁。
二、诊断标准:
1、腹腔内出血多时呈贫血貌;大量腹腔内出血致失血性休克时,患者面色苍白,四肢湿冷,脉快、细、弱,血压下降;
2、下腹有明显压痛、反跳痛,尤以患侧为著,但腹肌紧张较轻,内出血多时可出现移动性浊音;
3、阴道内可有少量暗红色血液,后穹窿可饱满、触痛,宫颈可有举痛或摆痛,子宫相当于停经月份或略大而软,宫旁可触及有轻压痛的包块;内出血多时,子宫有漂浮感。
三、用法用量:临床应用时,一天一剂,水煎两遍取汁约300ml,分早、晚两次饭前半小时温热服用,5天为一疗程。服药期间忌食生冷、辛辣之物。
四、疗效标准:
1、治愈:症状和体征消失,妊娠试验阴性,血HCG正常,盆腔包块消失;
2、好转:症状和体征好转,盆腔包块缩小或无增大,血HCG有所下降;
3、未愈:症状和体征未改善或加重,盆腔包块增大或无变化,血HCG不降或升高。
五、治疗效果:该临床观察病例中,服药2-6个疗程,治愈35例,好转14例,未愈9例。治疗期间未发生毒副作用。
六、典型病例:
病例1:孙某,女,24岁。就诊时自述:停经2个半月,一周前出现左下腹疼痛,阴道少量出血,并伴有恶心、呕吐、面色苍白。B超结果显示:宫外孕。医生建议手术,但患者坚持保守治疗。服用本发明的中药组合物制备的药剂1个疗程后,自觉腹痛感减轻,阴道有红色分泌物流出,食欲好转;继续服用3个疗程,症状消失,尿检呈阴性,B超检查正常,治愈。
病例2:田某,女,28岁。就诊时自述:两年内患有两次宫外孕,第一次宫外孕时,由于想保存生育能力,没有选择手术治疗,多次服用治疗宫外孕的抗生素类药物,但效果并不显著,其药物反应还经常引起身体不适。3个月前突然出现小腹疼痛,且疼痛逐渐加重,再次被诊为宫外孕。服用本发明的中药组合物制备的药剂2个疗程,不适感显著减轻,尿HCG呈弱阳性;续服3个疗程后,各症状消失,复查结果显示为正常。随访一年,已妊娠5个月,各项指标正常。

Claims (2)

1.一种治疗宫外孕的中药组合物,其特征在于:其中药原料及重量份配比为:丹参10-30份,锁阳10-20份,莪术5-15份,紫草10-20份,红藤10-20份,麦冬10-20份,陈皮5-15份,水红花子10-20份,菟丝子10-20份,五灵脂5-15份,蒲公英10-20份,牡丹皮10-20份,红花5-15份,薏苡仁10-20份,白花蛇舌草10-20份,紫石英10-20份,竹茹5-15份,大黄10-20份,昆布10-20份,天花粉10-20份,甘草5-15份。
2.根据权利要求1所述的一种治疗宫外孕的中药组合物,其特征在于:其中药原料及重量份配比为:丹参20份,锁阳15份,莪术10份,紫草15份,红藤15份,麦冬15份,陈皮10份,水红花子15份,菟丝子15份,五灵脂10份,蒲公英15份,牡丹皮15份,红花10份,薏苡仁15份,白花蛇舌草15份,紫石英15份,竹茹10份,大黄15份,昆布15份,天花粉15份,甘草10份。
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