CN105770974A - Preparation method of medical biological dressing for haemorrhoids - Google Patents

Preparation method of medical biological dressing for haemorrhoids Download PDF

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Publication number
CN105770974A
CN105770974A CN201610140643.5A CN201610140643A CN105770974A CN 105770974 A CN105770974 A CN 105770974A CN 201610140643 A CN201610140643 A CN 201610140643A CN 105770974 A CN105770974 A CN 105770974A
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CN
China
Prior art keywords
preparation
biological dressing
alginate
parts
haemorrhoids
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Pending
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CN201610140643.5A
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Chinese (zh)
Inventor
李苏扬
李文遐
徐勤霞
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Suzhou Bec Biological Technology Co Ltd
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Suzhou Bec Biological Technology Co Ltd
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Priority to CN201610140643.5A priority Critical patent/CN105770974A/en
Publication of CN105770974A publication Critical patent/CN105770974A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a preparation method of a medical biological dressing for haemorrhoids. The preparation method comprises the steps as follows: firstly, raw materials are weighed in parts by weight, put in a reactor and evenly mixed, the solution temperature is maintained to be 110 DEG C, and heating is performed for 10 minutes; secondly, the heated mixture is poured into a membrane production mold, strickled flat and fully dried, then demolding is performed, and a medicine storing layer is prepared; thirdly, the prepared medicine storing layer and base fabric are bonded and compounded through a binder, and a dense microporous puncturing machine is used for puncturing the bonded composite; the punctured dense composite is cut into a required shape and sealed for sterilization. The biological dressing prepared with the method adopts a traditional Chinese medicine formula and has small irritation, but has no toxic or side effects; haemorrhoids cannot easily relapse; the biological dressing has the advantages of taking effect rapidly, being absorbed completely, not injuring the mucosa and being clean and sanitary, is good in treatment effect, capable of fully playing the pharmacodynamic effect and long in acting duration, and has quite good treatment effects on bleeding, swelling, pains and the like caused by haemorrhoids.

Description

A kind of preparation method of medical hemorrhoid biological dressing
Technical field
The invention belongs to medical bio field of new, the preparation method relating to a kind of medical hemorrhoid biological dressing.
Technical background
In recent years, development along with society, the pressure of people is increasing, regular overtime work, causes that the time sat is oversize, add the change of dietary structure and dietary habit, the diet taste that height is warm, pungent, heavy wool becomes many people, and fat caused abdominal pressure increase, make the sickness rate of hemorrhoid substantially rise, in whole anorectal disease, the sickness rate of hemorrhoid accounts for 87.3%.Hemorrhoid are to be expanded, with venous plexus flexing under anal canal skin, the soft vein group formed by under human rectum's end mucosa.Hemorrhage, scratch where it itches, pain and to deviate from be four kinds of common clinical manifestation of hemorrhoid, hemorrhoid are also easy to other systemic diseases such as causing anal and intestinal disease, anemia, gynecological inflammation, anal eczema, vegetative nerve wadding disorderly simultaneously.Therefore hemorrhoid are treated timely, extremely important.
At present the Therapeutic Method of hemorrhoid there is operative therapy, medicine therapy for oral administration and medicine Topical therapy, operative therapy brings bigger misery to patient, complication is easily produced after being ill, and medicine therapy curative effect for oral administration is slow, the dosage form that medicine Topical therapy uses mostly is lotion, the time of washing is typically more of short duration, the time that medicament contacts with mucosa is little, medicine can not retain simultaneously, medicine can not be played a role fully, and curative effect is very micro-, zest is bigger, even a lot of people are for fast treating hemorrhoid, adopt injection for curing, but injection for curing can serve side effect by band, and often run hospital, cause inconvenience.
Biological dressing is the Novel wound reparation and protection material that grow up in repair in trauma " moistening healing " theoretical basis proposed such as Winter.Compared with traditional dressing, biological dressing has reduction and infects, improves wound healing quality, alleviate the misery of patient and facilitate the advantages such as medical personnel's operation, therefore obtains the favor of people.At present, dressing that is that China market has independent intellectual property right and that repair for hemorrhoid is also little, is almost blank.Therefore, study the novel dressing for hemorrhoid reparation and preparation method, be extremely important.
Summary of the invention
Present invention aims to the deficiencies in the prior art, it is provided that the preparation method of a kind of medical hemorrhoid biological dressing.
It is an object of the invention to be achieved through the following technical solutions: the preparation method of a kind of medical hemorrhoid biological dressing, this preparation method comprises the following steps: by weight, weigh Fibrin Glue 30-35 part, chitosan 30-35 part, chitin 5-10 part, alginate 4-12 part, astragalus membranaceus powder 10-20 part, balloonflower powder 10-20 part, Rhizoma Chuanxiong power 14-20 part, Radix Angelicae Sinensis powder 10-15 part, Fructus Lycii powder 11-17 part, glycyrrhizic acid dipotassium 6-10 part, hyaluronate sodium 10-14 part, emulsifying agent 3-10 part and water 30-40 part are placed in after stirring in reactor, keeping solution temperature is 110 DEG C, after heating 10 minutes；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Biological dressing prepared by the method by the present invention that the method have the advantages that adopts Chinese medicine formula, zest is little, have no side effect, not easily recur, have rapid-action, absorb completely, do not hinder mucosa, the advantage of clean hygiene, good effect, it is possible to give full play to drug action, acting duration is long, and hemorrhage, swelling that external hemorrhoid is caused, pain, constipation etc. all have good curative effect.
Detailed description of the invention
Embodiment 1
A kind of preparation method of medical hemorrhoid biological dressing, this preparation method comprises the following steps: by weight, weigh Fibrin Glue 33 parts, chitosan 33 parts, chitin 8 parts, alginate 8 parts, astragalus membranaceus powder 15 parts, balloonflower powder 15 parts, Rhizoma Chuanxiong power 17 parts, Radix Angelicae Sinensis powder 13 parts, Fructus Lycii powder 14 parts, glycyrrhizic acid dipotassium 8 parts, hyaluronate sodium 12 parts, emulsifying agent 6 parts and 35 parts of water to be placed in after reactor stirs, keeping solution temperature is 110 DEG C, after heating 10 minutes；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Embodiment 2
A kind of preparation method of medical hemorrhoid biological dressing, this preparation method comprises the following steps: by weight, weigh Fibrin Glue 30 parts, chitosan 30 parts, chitin 5 parts, alginate 4 parts, astragalus membranaceus powder 10 parts, balloonflower powder 10 parts, Rhizoma Chuanxiong power 14 parts, Radix Angelicae Sinensis powder 10 parts, Fructus Lycii powder 11 parts, glycyrrhizic acid dipotassium 6 parts, hyaluronate sodium 10 parts, emulsifying agent 3 parts and 30 parts of water to be placed in after reactor stirs, keeping solution temperature is 110 DEG C, after heating 10 minutes；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Embodiment 3
A kind of preparation method of medical hemorrhoid biological dressing, this preparation method comprises the following steps: by weight, weigh Fibrin Glue 35 parts, chitosan 35 parts, chitin 10 parts, alginate 12 parts, astragalus membranaceus powder 20 parts, balloonflower powder 20 parts, Rhizoma Chuanxiong power 20 parts, Radix Angelicae Sinensis powder 15 parts, Fructus Lycii powder 17 parts, glycyrrhizic acid dipotassium 10 parts, hyaluronate sodium 14 parts, emulsifying agent 10 parts and 40 parts of water to be placed in after reactor stirs, keeping solution temperature is 110 DEG C, after heating 10 minutes；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.

Claims (5)

1. the preparation method of a medical hemorrhoid biological dressing, it is characterized in that this preparation method comprises the following steps: by weight, weigh Fibrin Glue 30-35 part, chitosan 30-35 part, chitin 5-10 part, alginate 4-12 part, astragalus membranaceus powder 10-20 part, balloonflower powder 10-20 part, Rhizoma Chuanxiong power 14-20 part, Radix Angelicae Sinensis powder 10-15 part, Fructus Lycii powder 11-17 part, glycyrrhizic acid dipotassium 6-10 part, hyaluronate sodium 10-14 part, emulsifying agent 3-10 part and water 30-40 part to be placed in after reactor stirs, keeping solution temperature is 110 DEG C, after heating 10 minutes；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
2. the preparation method of a kind of medical hemorrhoid biological dressing according to claim 1, it is characterised in that: described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
3. the preparation method of a kind of medical hemorrhoid biological dressing according to claim 1, it is characterised in that: described binding agent is pressure sensitive adhesive.
4. the preparation method of a kind of medical hemorrhoid biological dressing according to claim 1, it is characterised in that: described alginate is potassium alginate, sodium alginate or calcium alginate.
5. the preparation method of a kind of medical hemorrhoid biological dressing according to claim 1, it is characterised in that: described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
CN201610140643.5A 2016-03-14 2016-03-14 Preparation method of medical biological dressing for haemorrhoids Pending CN105770974A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057437A (en) * 2019-12-10 2020-12-11 江苏一全药业有限公司 Pharmaceutical preparation containing hyaluronic acid, pharmaceutical transdermal patch and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2267043Y (en) * 1996-03-29 1997-11-12 康克 Adhesive plaster for treating hemorrhoid
CN104324411A (en) * 2014-09-28 2015-02-04 张亚峰 Medical natural marine organism dressing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2267043Y (en) * 1996-03-29 1997-11-12 康克 Adhesive plaster for treating hemorrhoid
CN104324411A (en) * 2014-09-28 2015-02-04 张亚峰 Medical natural marine organism dressing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
魏成广等: "《中国钾盐工业概览 第1版》", 31 July 2009, 上海交通大学出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057437A (en) * 2019-12-10 2020-12-11 江苏一全药业有限公司 Pharmaceutical preparation containing hyaluronic acid, pharmaceutical transdermal patch and preparation method thereof
CN112057437B (en) * 2019-12-10 2021-08-06 江苏一全药业有限公司 Pharmaceutical preparation containing hyaluronic acid, pharmaceutical transdermal patch and preparation method thereof

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