CN105770842A - 一种治疗癌症的中成药及其制备方法 - Google Patents

一种治疗癌症的中成药及其制备方法 Download PDF

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CN105770842A
CN105770842A CN201610317763.8A CN201610317763A CN105770842A CN 105770842 A CN105770842 A CN 105770842A CN 201610317763 A CN201610317763 A CN 201610317763A CN 105770842 A CN105770842 A CN 105770842A
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radix
rhizoma
herba
fructus
semen
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王顺
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Abstract

本发明涉及一种治疗癌症的中成药及其制备方法，属于药品(中成药)技术领域。其特征在于组成原料由白花蛇舌草、半枝莲、夏枯草、藤梨根、石上柏、益母草、八月扎、天葵子、土茯苓、葶苈子、木鳖子、蚤休、全蝎、蜈蚣、守宫、龙葵、山豆根、皂角刺等组成，辅料有蜂蜜、糊精、山梨酸钾、苹果酸、柠檬酸、黄原胶、三氯蔗糖、维生素C、饮用水。可制成饮料化汤剂、蜜丸和粉剂，功效：治疗乳腺癌、食道癌、肺癌、肝癌、淋巴癌、胃肠癌、前列腺癌等各类癌肿；具有止吐和胃、回阳救逆、滋阴补阳、祛痰渗湿、活血化瘀、通便排毒、清热解毒、消块止痛、补气健脾、理气解郁等功效。

Description

一种治疗癌症的中成药及其制备方法
技术领域：本发明涉及一种治疗癌症的中成药及其制备方法，属于药品(中成药)技术领域。
背景技术：。经专利检索，专利号为CN105288256A一种治疗癌症的中成药，原料组成是：紫河车、重楼、毛茨菇、硇砂、硼砂、元明粉、牛黄、麝香、蟾酥、斑蝥、黄连，制装成胶囊；专利号CN101912544A一种治疗癌症的中成药，原料组成：陈皮、蝉蜕、半夏、乌蛇、木瓜、海藻、红花、胆星、地龙、竹茹、川芎、藏红花、黄芩、蜈蚣、赤芍、僵蚕、天麻、全蝎、乳香、末药、土茯苓、大黄、朱砂。专利CN1709316A一种治疗癌症的中成药，原料组成是：壁虎、山慈姑、藤黄、红景天、麝香、三七、水蛭、鹿茸、鸦旦子、牛黄、鳖甲、蟾蜍、蜂胶、人参、鸡内金、冰片。这三个专利配方对部分癌症均应有一定疗效，比较适宜于部分早中期癌症患者，但由于配方的局限性，对各类癌症的通用性和中晚期癌症患者的适用性较差，特别是经过手术、放化疗后或久拖不治的危急癌症患者可能无能为力或收效甚微，市场急需一种既能挽救危急癌症患者生命又能扶正消癌肿的药品。遗憾的是，目前还没有一种具有治疗癌症综合功效的技术方案及产品。
发明内容：本发明的目的就是利用纯中草药(草本)，运用中医辨证机理，结合癌症患者复杂且危急的心理、生理、病理状况，科学配伍组方，确定创造性的技术方案和制备方法，开发出崭新的对各类癌症具有综合治疗功效的中成药，以满足癌症患者治病救命所急需；同时达到对各类患者体质具有广泛的适用性、长期服用安全无副作用的目标。
具体的技术方案由原料组成、组份配比来体现，本发明所涉及的一种治疗癌症的中成药及其制备方法，原料组成及组份配比如下：白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、葶苈子(25-120)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、黄药子(10-100)、半夏(6-68)、南星(5-75)、天花粉(12-120)、柴胡(10-80)、川楝子(5-83)、香附(8-97)、枳实(12-90)、徐长卿(15-105)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、儿茶(15-76)、当归(10-100)、威灵仙(12-110)、穿山甲(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、人参(5-120)、黄芪(10-100)、刺五加(15-120)、胶股蓝(15-100)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、玄参(15-108)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、石苇(20-100)、白术(10-90)、茯苓(15-110)、神曲(15-95)、甘草(20-120)、枸杞(20-120)、红枣(15-100)大黄(10-100)、芒硝(10-80)、合欢皮(15-90)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成，辅料有蜂蜜、糊精、山梨酸钾、苹果酸、柠檬酸、黄原胶、三氯蔗糖、维生素C、饮用水。
其制备方法分为三种：一是制备成饮料化瓶装汤剂，二是制备成粉剂，三是制备成蜜丸。患者可根据自己需要选用(用法及用量按产品说明书)，患者在服用饮料化瓶装汤剂时，应同时服用粉剂或蜜丸，以提高治疗效果。
饮料化瓶装汤剂的制备方法：上述配方中除蚤休、全蝎、蜈蚣、守宫、雄黄、穿山甲、土鳖虫外其余原料清选清洗干净---加饮用水至没过原料10cm---加热至沸腾调至小火再煎30分钟---滤汁后再加入同样量的饮用水并加热至沸腾调至小火煎30分钟---滤汁后再加同样量的饮用水并加热至沸腾调至小火煎30分钟/滤汁并浓缩至50％---将三次滤汁混匀并按国家食品添加剂标准限量加入山梨酸钾、苹果酸、柠檬酸、黄原胶、三氯蔗糖、维生素C/充分搅拌均匀---杀菌---过滤---灌装、检验--入库。
粉剂的制备方法：将上述配方中的所有原料(不含辅料)清选干净---粉碎2或3次并过筛(200-300目)---混匀---杀菌---分装---检验---入库。
蜜丸的制备方法：将上述配方中的所有原料(不含辅料)清选干净---粉碎2或3次并过筛(200-300目)---混匀---加入炼蜜、米胎、糊精---制成面团并用制丸机制丸---干燥杀菌--分装---检验--入库。
本发明的有益效果，是由配方所选中草药(草本)原料、组份配比及其制备方法予以体现的，具体有益效果包括：治疗乳腺癌、食道癌、肺癌、肝癌、淋巴癌、胃肠癌、前列腺癌等各类癌肿；具有止吐和胃、回阳救逆、滋阴补阳、祛痰渗湿、活血化瘀、通便排毒、清热解毒、消块止痛、补气健脾、理气解郁等功效；由于配方是对心肝脾肺肾及全身进行综合调理，也适用于糖尿病、中风瘫痪等慢性疑难重病。
通过以上的中草药(草本)群组原料配伍，对患者全身五脏六腑进行系统综合调理，实现阴阳平衡、寒热平衡、扶正固本、攻补结合、救人治病、缩小或避免患者体质个体差异性反应，增强本发明所涉及的中成药治疗各类癌症的广泛适用性和有效性，并拓展了该中成药对糖尿病、中风瘫痪等慢性疑难重病治疗的适用性。由于配伍的科学独创性，选用原料的低毒性，确保了患者长期服用的安全性。
本发明具体实施方式，有三个方面：一是按上述饮料化瓶装汤剂的制备方法制成的中成药汤剂，用于危急重症及极度虚弱癌症患者；二是按上述粉剂的制备方法，生产成中成药粉剂，粉剂效果好，但服用时部分患者觉得太难吃了，适用于肠胃仍较好的患者及吞咽困难的患者；三是按上述蜜丸的制备方法制成的中成药丸剂，除吞咽困难的患者外具有广泛的适用性。优选实施方式是生产成饮料化瓶装汤剂和蜜丸，因为患者易于服用，有利于治病救人，当然粉剂也要生产，搭配汤剂服用可以提高疗效。

Claims (6)

1.一种治疗癌症的中成药及其制备方法，其特征在于它是由下述配方及重量配比的原料及辅料组成：白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、葶苈子(25-120)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、黄药子(10-100)、半夏(6-68)、南星(5-75)、天花粉(12-120)、柴胡(10-80)、川楝子(5-83)、香附(8-97)、枳实(12-90)、徐长卿(15-105)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、儿茶(15-76)、当归(10-100)、威灵仙(12-110)、穿山甲(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、人参(5-120)、黄芪(10-100)、刺五加(15-120)、胶股蓝(15-100)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、玄参(15-108)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、石苇(20-100)、白术(10-90)、茯苓(15-110)、神曲(15-95)、甘草(20-120)、枸杞(20-120)、红枣(15-100)大黄(10-100)、芒硝(10-80)、合欢皮(15-90)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成，辅料有蜂蜜、糊精、山梨酸钾、苹果酸、柠檬酸、黄原胶、三氯蔗糖、维生素C、饮用水。
2.如权利要求1所述的治疗癌症的中成药及其制备方法，其特征在于各原料组成及重量配比为白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、葶苈子(25-120)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、黄药子(10-100)、半夏(6-68)、南星(5-75)、天花粉(12-120)、柴胡(10-80)、川楝子(5-83)、香附(8-97)、枳实(12-90)、徐长卿(15-105)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、儿茶(15-76)、当归(10-100)、威灵仙(12-110)、穿山甲(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、人参(5-120)、黄芪(10-100)、刺五加(15-120)、胶股蓝(15-100)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、玄参(15-108)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、石苇(20-100)、白术(10-90)、茯苓(15-110)、神曲(15-95)、甘草(20-120)、枸杞(20-120)、红枣(15-100)大黄(10-100)、芒硝(10-80)、合欢皮(15-90)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成，辅料有蜂蜜、米胎、糊精。
3.如权利要求1所述的治疗癌症的中成药及其制备方法，其特征在于各原料组成及重量配比为白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、葶苈子(25-120)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、黄药子(10-100)、半夏(6-68)、南星(5-75)、天花粉(12-120)、柴胡(10-80)、川楝子(5-83)、香附(8-97)、枳实(12-90)、徐长卿(15-105)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、儿茶(15-76)、当归(10-100)、威灵仙(12-110)、穿山甲(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、人参(5-120)、黄芪(10-100)、刺五加(15-120)、胶股蓝(15-100)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、玄参(15-108)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、石苇(20-100)、白术(10-90)、茯苓(15-110)、神曲(15-95)、甘草(20-120)、枸杞(20-120)、红枣(15-100)大黄(10-100)、芒硝(10-80)、合欢皮(15-90)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成。
4.如权利要求1所述的治疗癌症的中成药及其制备方法，其特征在于各原料组成及重量配比为：白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、葶苈子(25-120)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、黄药子(10-100)、半夏(6-68)、南星(5-75)、天花粉(12-120)、柴胡(10-80)、川楝子(5-83)、香附(8-97)、枳实(12-90)、徐长卿(15-105)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、儿茶(15-76)、当归(10-100)、威灵仙(12-110)、穿山甲(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、人参(5-120)、黄芪(10-100)、刺五加(15-120)、胶股蓝(15-100)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、玄参(15-108)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、石苇(20-100)、白术(10-90)、茯苓(15-110)、神曲(15-95)、甘草(20-120)、枸杞(20-120)、红枣(15-100)大黄(10-100)、芒硝(10-80)、合欢皮(15-90)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成，辅料有山梨酸钾、苹果酸、柠檬酸、黄原胶、三氯蔗糖、维生素C、饮用水。
5.如权利要求1所述的治疗癌症的中成药及其制备方法，其特征在于各原料组成及重量配比为：白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、葶苈子(25-120)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、黄药子(10-100)、半夏(6-68)、南星(5-75)、柴胡(10-80)、川楝子(5-83)、香附(8-97)、枳实(12-90)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、儿茶(15-76)、威灵仙(12-110)、穿山甲(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、人参(5-120)、黄芪(10-100)、刺五加(15-120)、胶股蓝(15-100)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、玄参(15-108)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、神曲(15-95)、甘草(20-120)、大黄(10-100)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成。
6.如权利要求1所述的治疗癌症的中成药及其制备方法，其特征在于各原料组成及重量配比为：白花蛇舌草(15-100)、半枝莲(10-80)、夏枯草(16-75)、藤梨根(10-90)、石上柏(20-100)、益母草(10-80)、八月扎(20-80)、天葵子(15-82)、土茯苓(10-90)、木鳖子(15-83)、蚤休(15-66)、全蝎(8-64)、蜈蚣(8-64)、守宫(10-105)、龙葵(10-77)、山豆根(12-88)、皂角刺(5-91)、败酱草(20-79)、射干(15-120)、急性子(10-70)、雄黄(5-60)、海蛤粉(10-90)、山慈菇(3-100)、半夏(6-68)、南星(5-75)、天花粉(12-120)、川楝子(5-83)、香附(8-97)、枳实(12-90)、川芎(20-100)、王不留行(10-110)、桃仁(8-82)、没药(10-105)、丹参(10-120)、三棱(10-100)、莪术(10-100)、土鳖虫(6-100)、黄芪(10-100)、刺五加(15-120)、代赭石(12-108)、吴茱萸(10-77)、干姜(10-100)、桂枝(10-100)、附子(6-120)、仙茅(5-100)、补骨脂(8-96)、淫羊藿(15-100)、牡蛎(15-88)、鳖甲(6-120)、白芍(10-100)、山枣皮(20-120)、白术(10-90)、茯苓(15-110)、神曲(15-95)、大黄(10-100)、合欢皮(15-90)、刘寄奴(10-120)、大血藤(12-95)、紫花地丁(15-100)、漏芦(10-100)组成。
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