CN105770657A - Traditional Chinese medicinal preparation for treating enterobiasis and preparation method thereof - Google Patents
Traditional Chinese medicinal preparation for treating enterobiasis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating enterobiasis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. Active ingredients of the traditional Chinese medicinal preparation provided by the invention are prepared from the following raw materials: herba polygoni avicularis, fructus quisqualis, fructus ulmi, pericarpium zanthoxyli, bear gall, radix stemonae, Chinese asafoetida, blumea balsamifera, uraria crinia, luisia morsei rolfe, pyrethrum cinerariifolium, semen torreyae, a common aeschynomene herb, a Chinese wisteria seed, cortex meliae and bombyx batryticatus. Medicinal materials which are selected for the traditional Chinese medicinal preparation provided by the invention are appropriate in compatibility, and accord with the theories of the traditional Chinese medicinal science and the modern medicinal science; the traditional Chinese medicinal preparation for treating the enterobiasis has the functions of detoxifying, expelling a parasite, clearing away heat and a toxic material, removing dampness, relieving itching, killing the parasite and eliminating stagnation, is convenient to use, is good in absorption effect, has no ill, toxic and side effects, through being clinically verified, has wonderful remission and treatment effects for treating the enterobiasis, and is applicable to the clinical treatment and the nursing popularization and application of the enterobiasis.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for treating enterobiasis and preparation method.
Background technology
Enterobiasis is to cause a kind of intestinal parasitical diseases that anus, perineal position pruritus are feature.Popular extremely wide all over the world, the whole world infects population 300~500,000,000, and south China, the north are generally popular, and childhood infection rate is higher than adult.Especially collective's institution child infection rate is high.
People is the only host of pinworm, and retrofection person is the only source of infection of enterobiasis.Spread path has self and allosome to infect two kinds.Autoinfection is that female worm creeps night anus, lays eggs around, cause and very itch on skin, and children's is infected with worm's ovum by finger pruritus.On the feed or swallow worm and incubate when sucking.Worm incubates and starts to hatch into larva of a tapeworm or the cercaria of a schistosome worm at stomach and duodenum, finally grows for adult at small intestinal hypomere and big enteral.Nymph incubates and hatches in anal orifice, and larva can crawl into anus, invades large intestine, causes retrograde infection.
The clinical manifestation of enterobiasis is:
1, perianal or perineal position pruritus
Being the toxicant produced by pinworm and mechanical stimulus is produced, night, more so impact sleep, children's cry and screamed uneasiness.Cause skin around the rectum to come off after scratching owing to very itching, hyperemia, erythra, eczema.Even bring out pyogenic infection.
2, symptom of digestive tract
Pinworm pierces intestinal mucosa, and mechanically or chemically sexual stimulus can cause the symptoms such as loss of appetite, Nausea and vomiting, stomachache, diarrhoea in gastrointestinal tract.
3, mental symptom
Due to the metabolite that parasite is discharged in vivo, causing mental excitation, insomnia uneasiness, children's's fright at night stings finger etc..Enterobiasis patient is most commonly seen addicted to symptom for children's different, such as addiction soil block, cinder, Sal etc..
4, other symptoms
Caused by the heterotopic parasitism of pinworm, as: vaginitis, salpingitis, endometritis etc..Also can invade vermiform appendix generation appendicitis, peritonitis even occurs.
Enterobiasis is very harmful, should not be underestimated, it is necessary to takes prevention to combine with deworm, could effect a radical cure.The medicine being currently used for treatment enterobiasis has a lot, such as mebendazole, pyrvinium embonate, pyrantel etc., though these medicine instant effects, but there is certain side effect, not easily long-term taking.And for treat enterobiasis recover medicine must safely, effectively, have no side effect, Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect strong, instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of Chinese medicine preparation to be used for treating enterobiasis to recover, for treatment enterobiasis, there is highly important clinical meaning.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for treating enterobiasis and preparation method, selected medical material compatibility is suitable, meet Chinese medicine and modern medicine is theoretical, there is effect of removing toxic substances anthelmintic, heat-clearing and toxic substances removing, removing damp to relieve itching, killing insect and eliminating accumulation, easy to use, good absorbing effect, without bad and toxic and side effects, according to clinical verification, treatment enterobiasis there are fabulous alleviation and therapeutic effect, are suitable to clinical treatment and the nursing popularization and application of enterobiasis.
For achieving the above object, technical scheme is implemented as follows:
A kind of Chinese medicine preparation for treating enterobiasis, make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Chinese medicine preparation for treating enterobiasis, comprises the following steps that:
(1) by storage, Fructus Ulmus preparatium, the Radix Stemonae, Herba Blumeae Balsamiferae, Herba urariae macrostachyae and Cortex Meliae remove impurity, clean, put in container, add 3 times amount yellow wine and 6 times amount distilled water, after soaking 2~3 hours, after add 5 times amount distilled water, decoct 2 hours, extraction decoction liquor;Adding 3~4 times amount distilled water, decoct 1.5 hours, extract decoction liquor, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, being condensed at 60 DEG C relative density is the thick paste of 1.10~1.13, standby;
(2) Fructus Quisqualis, Fel Ursi, Resina Ferulae, Radix Seu Herba Luisiae Morsei, Pyrethrum and Herba Aeschynonenes Indicae are removed impurity, clean, dry, be placed in mortar and grind into powder, obtained the fine powder of 1160 orders, standby;
(3) Pericarpium Zanthoxyli, Semen Torreyae and Semen Wisteriae sinensis are removed impurity, clean, be placed in pot quick-fried, fry to well-done, take out and dry in the air cool, be placed in mortar and grind into powder, obtained the fine powder of 180 orders, standby;
(4) Bombyx Batryticatus is soaked one with Oryza sativa L. var. glutinosa Matsum., treats that silkworm and mulberry saliva goes out as on Limax saliva bubbles through the water column, after filter out, low baking temperature dries, and only wipes the upper yellow meat hair of silkworm with cloth, smashs to pieces and grind into powder, obtained the fine powder of 200 orders, standby;
(5) by the thick paste of step (1) gained and step (2), step (3), step (4) gained fine powder make tablet, be the described Chinese medicine preparation for treating enterobiasis.
The property of medicine of Chinese medicine used by the present invention is as follows:
Store: bitter in the mouth, cold nature;Return bladder warp.Inducing diuresis for treating stranguria syndrome, killing parasites for relieving itching.For bladder pyretic stranguria, oliguria with reddish urine, drench the puckery pain of drop, skin eczema, pudendal pruritus leukorrhagia." herbal classic " carries: " main contamination, scabies scabies cellulitis hemorrhoid kill three worms.”
Fructus Quisqualis: sweet in the mouth, warm in nature;Return spleen, stomach warp.Parasite killing, removing food stagnancy, spleen invigorating.Suffering from abdominal pain for ascarid, infantile malnutrition, breast food is stagnated, abdominal distention dysentery." Kaibao Bencao " carries: " main children's's five kinds of child malnutrition, urine nebulousurine treat dysentery.”
Fructus Ulmus preparatium: acrid in the mouth, hardship, property is put down;Return spleen, stomach warp.Killing insect and eliminating accumulation.For abdominal pain due to worm stagnation, children's's infantile malnutrition with diarrhea, cold-dysentery, scabies, malignant boil." Haiyao Bencao, Oversea Materia Medica " carries: " control the cold-dysentery motive, parasite killing pain relieving.Control again married woman uterus wind empty, child's infantile malnutrition with diarrhea.”
Pericarpium Zanthoxyli: acrid in the mouth, warm in nature;Return spleen, stomach, kidney channel.Warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing, solve fish raw meat poison.Stop drink, trusted subordinate's cold type of pain for food stagnation, vomit oh, cough with dyspnea, anemofrigid-damp arthralgia, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies." detailed outline " carries: " dispelling cold and removing dampness, stagnation resolving, disappear dyspepsia, and logical three is burnt, and warming the spleen stomach is mended the right kidney gate of vitality, killed ascarid, and stopping leak rushes down.”
Fel Ursi: bitter in the mouth, cold in nature;Return liver, gallbladder, Pi, stomach warp.Clearing away heat and relieving spasm, improving eyesight parasite killing.Yellow for heat, diarrhea due to summer-heat, children's shies chronic, infantile malnutrition, ascarid pain, corneal nebula, and sore throat, nose loses, furuncle hemorrhoid malignant boil." detailed outline " carries: " bring down a fever, clear away heart-fire, suppressing the hyperactive liver, improving eyesight removing nebula, kill ascarid, pinworm.”
The Radix Stemonae: sweet in the mouth, hardship, slightly warm in nature;Return lung meridian.Nourishing the lung to keep the adverse QI downward, cough-relieving parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis, head louse, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For deficiency of YIN chronic cough." Japan hanako materia medica " carries: " controls infantile malnutrition ascarid and passes corpse steaming labor, killing ascarid, very little white, pinworm.”
Resina Ferulae: bitter in the mouth, pungent, warm in nature;Return spleen, stomach warp.Removing food stagnancy, dissipates painful abdominal mass, parasite killing.For meat stagnation, blood stasis lump in the abdomen, mass in abdomen, abdominal pain due to worm stagnation.Tang Materia Medica carries: " master kills all small worms, gas of deodorizing, and broken disease is amassed, lower bad odor.”
Herba Blumeae Balsamiferae: acrid in the mouth, hardship, warm in nature.Warming middle-JIAO is invigorated blood circulation, expelling wind and removing dampness, parasite killing.For cold-damp dysentery, borborygmus of suffering from abdominal pain, swelling, bones and muscles pain, traumatic injury, tinea skin ulcer." Kaibao Bencao " carries: " remove bad odor, parasite killing.Main abdomen is cold lets out dysentery.”
Herba urariae macrostachyae: lightly seasoned, cool in nature.Removing heat-phlegm, cooling blood for hemostasis, parasite killing.For catching a cold, cough, malaria, filaricide, infantile malnutrition, spit blood, spitting of blood, hematuria." south of the Five Ridges herbal " carries: " antipyretic, parasite killing.Control filaricide, malaria.”
Radix Seu Herba Luisiae Morsei: acrid in the mouth, hardship, property is put down;Return liver, kidney channel.Emetic removing toxic substances, expelling wind and removing dampness.For malaria, carbuncle, rheumatalgia, edema." register planted by Guangxi medicine " carries: " circulation of qi promoting, tonifying YANG, parasite killing, emetic.”
Pyrethrum: bitter in the mouth, cool in nature.Parasite killing.For scabies, can mosquito killing, fly, louse, kill maggot, anophelifuge.
Semen Torreyae: sweet in the mouth, property is put down;Return lung, stomach, large intestine channel.Killing insect and eliminating accumulation, moistening dryness for relaxing bowels.For ancylostome, ascarid, taeniasis, abdominal pain due to worm stagnation, infantile malnutrition, constipation." herbal classic " carries: " pathogen in main abdomen, goes three worms, and Serpentis stings.”
Herba Aeschynonenes Indicae: sweet in the mouth, light, cold in nature;Return lung, Liver Channel.Wind is removed in heat clearing away, inducing diuresis and reducing edema.For anemopyretic cold, jaundice, dysentery, gastritis, abdominal distention, gonorrhea, carbuncle, dermatitis, eczema." Zhiwu Mingshi Tukao " carries: " remove wind, parasite killing.”
Semen Wisteriae sinensis: sweet in the mouth, slightly warm in nature, slightly poisonous;Return liver, stomach, large intestine channel.Promoting blood circulation to remove obstruction in the collateral, anthelmintic of detoxifying.For bones and muscles pain, stomachache is vomited and diarrhoea, infantile oxyuriasis." Chinese herbal medicine handbook " carries: " parasite killing, pain relieving, removing toxic substances.”
Cortex Meliae: bitter in the mouth, cold in nature, poisonous;Return liver, spleen, stomach warp.Heat clearing away, dampness, parasite killing.For ascarid, pinworm, rubella, scabies." modern Practical Chinese medicinal " load: " root bark is all effective to cestode, ascarid, pinworm.”
Bombyx Batryticatus: acrid in the mouth, salty, property is put down;Return liver, lung, stomach warp.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.For apoplectic aphasia, infantile convulsion wind syndrome of head, acute throat trouble sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis." herbal classic " carries: " main pediatric epilepsy scared night cry, goes three worms, goes out black, and man's the moon infections is sick.”
The present invention compared with prior art, has the advantages that
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine is theoretical, there is effect of removing toxic substances anthelmintic, heat-clearing and toxic substances removing, removing damp to relieve itching, killing insect and eliminating accumulation, easy to use, good absorbing effect, without bad and toxic and side effects, according to clinical verification, treatment enterobiasis there are fabulous alleviation and therapeutic effect, are suitable to clinical treatment and the nursing popularization and application of enterobiasis.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) by storage, Fructus Ulmus preparatium, the Radix Stemonae, Herba Blumeae Balsamiferae, Herba urariae macrostachyae and Cortex Meliae remove impurity, clean, put in container, add 3 times amount yellow wine and 6 times amount distilled water, after soaking 2~3 hours, after add 5 times amount distilled water, decoct 2 hours, extraction decoction liquor;Adding 3~4 times amount distilled water, decoct 1.5 hours, extract decoction liquor, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, being condensed at 60 DEG C relative density is the thick paste of 1.10~1.13, standby;
(2) Fructus Quisqualis, Fel Ursi, Resina Ferulae, Radix Seu Herba Luisiae Morsei, Pyrethrum and Herba Aeschynonenes Indicae are removed impurity, clean, dry, be placed in mortar and grind into powder, cross 140 order fine powders, standby;
(3) Pericarpium Zanthoxyli, Semen Torreyae and Semen Wisteriae sinensis are removed impurity, clean, be placed in pot quick-fried, fry to well-done, take out and dry in the air cool, be placed in mortar and grind into powder, cross 150 order fine powders, standby;
(4) Bombyx Batryticatus is soaked one with Oryza sativa L. var. glutinosa Matsum., treats that silkworm and mulberry saliva goes out as on Limax saliva bubbles through the water column, after filter out, low baking temperature dries, and only wipes the upper yellow meat hair of silkworm with cloth, smashs to pieces, cross 160 order fine powders, standby;
(5) by the thick paste of step (1) gained and step (2), step (3), step (4) gained fine powder make tablet, be the Chinese medicine preparation for treating enterobiasis of the present invention.
Usage and dosage: oral, every day 3 times, each 2,2 days be a course for the treatment of, usual 1~2 onset course for the treatment of, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Clinical data:
1, case selection:
Selecting the enterobiasis patient 480 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group 240 example, wherein male 120 example, women 120 example, 4~75 years old age, 45 years old mean age, the course of disease 7 days~2 months, average 15 days.Matched group 240 example, wherein male 118 example, women 122 example, the age, 5~62 years old, 53 years old mean age, the course of disease 5 days~1 month, average 10 days.The course of disease of two groups of cases, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes this Chinese medicine preparation, oral, and every day 3 times, each 2,2 days be a course for the treatment of, usual 1~2 onset course for the treatment of, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Matched group takes mebendazole, each 100mg, takes day 2 times, serve on 3~4.
3, efficacy determination:
(1) cure: the transference cures such as abnormal food appetite, pruritus ani, nausea and vomiting, abdominal pain diarrhea;Health is fully recovered.
(2) effective: above-mentioned symptom is alleviated to some extent, health is fully recovered.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 190 examples, effective 40 examples, invalid 10 examples, cure rate 79.2%, total effective rate 95.8%.
Matched group is cured 100 examples, effective 88 examples, invalid 52 examples, cure rate 41.7%, total effective rate 78.3%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Xu's ××, female, 4 years old, child, Shanghai people.Patient's anus, perineal position pruritus, night, more so impact sleep, children's cry and screamed uneasiness.It is diagnosed as enterobiasis by my institute.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom is substantially alleviated, and continues to take 1 course for the treatment of, and clinical symptoms all disappears.Follow up a case by regular visits to and do not recur so far.
2, in ××, man, 7 years old, student, people from Binzhou, Shandong.Patient is stimulated by the toxicant produced by pinworm, and night, more so impact was slept.Cause skin around the rectum to come off after scratching owing to very itching, hyperemia, erythra, eczema, even bring out pyogenic infection.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, health is rehabilitation gradually, and symptom is substantially alleviated, and continues to take 1 course for the treatment of, above transference cure.Follow up a case by regular visits to and do not recur so far.
3, side's ××, female, 11 years old, student, people from Hefei ,Anhui.Patient pierces intestinal mucosa due to pinworm, and mechanical irritation causes the symptoms such as loss of appetite, Nausea and vomiting, stomachache, diarrhoea in gastrointestinal tract.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, and after continuing to take 1 course for the treatment of, above disappearance, physical recovery is healthy, it does not have recurrence.
4, Lee's ××, man, 41 years old, profession, people from Chaozhou, Fujian.The recent perianal pruritus of patient, insomnia uneasiness, mental excitation, addiction Sal etc., it is diagnosed as enterobiasis by my institute.Take Chinese medicine preparation of the present invention 1 the symptom course for the treatment of substantially to alleviate, after continuing to take 1 course for the treatment of, transference cure, follow up a case by regular visits to and do not recur.
5, gold ××, female, 60 years old, peasant, Wenzhou District of Zhejiang Province people.Patient is vaginitis caused by the heterotopic parasitism of pinworm, perineal position pruritus.Once taking multi-medicament, effect is all not good.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom takes a turn for the better, and after continuing to take 1 course for the treatment of, above transference cure, health is fully recovered, and gets well, follows up a case by regular visits to and do not recur so far.
6, ×× is opened, man, 71 years old, old people, Yinchuan of Ningxia Province people.Patient has enterobiasis, skin around the rectum to come off, hyperemia, once takes multi-medicament, poor effect.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after then taking 2 courses for the treatment of, physical recovery is normal.Follow up a case by regular visits to and do not recur so far.
Claims (5)
1. one kind for treating the Chinese medicine preparation of enterobiasis, it is characterised in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
2. one kind for treating the Chinese medicine preparation of enterobiasis, it is characterised in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
3. one kind for treating the Chinese medicine preparation of enterobiasis, it is characterised in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
4. one kind for treating the Chinese medicine preparation of enterobiasis, it is characterised in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
5. the preparation method of the Chinese medicine preparation for treating enterobiasis as described in any one of Claims 1 to 4, it is characterised in that: comprise the following steps that:
(1) by storage, Fructus Ulmus preparatium, the Radix Stemonae, Herba Blumeae Balsamiferae, Herba urariae macrostachyae and Cortex Meliae remove impurity, clean, put in container, add 3 times amount yellow wine and 6 times amount distilled water, after soaking 2~3 hours, after add 5 times amount distilled water, decoct 2 hours, extraction decoction liquor;Adding 3~4 times amount distilled water, decoct 1.5 hours, extract decoction liquor, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, being condensed at 60 DEG C relative density is the thick paste of 1.10~1.13, standby;
(2) Fructus Quisqualis, Fel Ursi, Resina Ferulae, Radix Seu Herba Luisiae Morsei, Pyrethrum and Herba Aeschynonenes Indicae are removed impurity, clean, dry, be placed in mortar and grind into powder, obtained the fine powder of 1160 orders, standby;
(3) Pericarpium Zanthoxyli, Semen Torreyae and Semen Wisteriae sinensis are removed impurity, clean, be placed in pot quick-fried, fry to well-done, take out and dry in the air cool, be placed in mortar and grind into powder, obtained the fine powder of 180 orders, standby;
(4) Bombyx Batryticatus is soaked one with Oryza sativa L. var. glutinosa Matsum., treats that silkworm and mulberry saliva goes out as on Limax saliva bubbles through the water column, after filter out, low baking temperature dries, and only wipes the upper yellow meat hair of silkworm with cloth, smashs to pieces and grind into powder, obtained the fine powder of 200 orders, standby;
(5) by the thick paste of step (1) gained and step (2), step (3), step (4) gained fine powder make tablet, be the described Chinese medicine preparation for treating enterobiasis.
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CN111567485A (en) * | 2020-06-19 | 2020-08-25 | 四川海泰克农业开发有限公司 | Method for feeding white muscardine silkworms in small scale |
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CN102078549A (en) * | 2010-12-29 | 2011-06-01 | 辛如才 | Traditional Chinese medicine for treating oxyuriasis |
CN104721662A (en) * | 2013-12-19 | 2015-06-24 | 陕西康乐中医药养生研究院 | Chinese medicinal preparation for treatment of enterobiasis |
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CN102078549A (en) * | 2010-12-29 | 2011-06-01 | 辛如才 | Traditional Chinese medicine for treating oxyuriasis |
CN104721662A (en) * | 2013-12-19 | 2015-06-24 | 陕西康乐中医药养生研究院 | Chinese medicinal preparation for treatment of enterobiasis |
Cited By (1)
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CN111567485A (en) * | 2020-06-19 | 2020-08-25 | 四川海泰克农业开发有限公司 | Method for feeding white muscardine silkworms in small scale |
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Application publication date: 20160720 |