CN105748927A - Traditional Chinese medicine preparation for preventing acute attack of gouty arthritis - Google Patents

Traditional Chinese medicine preparation for preventing acute attack of gouty arthritis Download PDF

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CN105748927A
CN105748927A CN201610156745.6A CN201610156745A CN105748927A CN 105748927 A CN105748927 A CN 105748927A CN 201610156745 A CN201610156745 A CN 201610156745A CN 105748927 A CN105748927 A CN 105748927A
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chinese medicine
medicine preparation
gouty arthritis
radix
acute attack
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陈利国
滕军燕
杜天信
郭智萍
郭珈宜
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Luoyang Orthopedic Traumatological Hospital of Henan Orthopedic Hospital
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陈利国
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Abstract

The invention provides a traditional Chinese medicine preparation for preventing acute attack of gouty arthritis, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine preparation for preventing acute attack of the gouty arthritis comprises raw material medicines as follows: 6 g-10 g of Chinese angelica, 6 g-10 g of dried tangerine peels, 6 g-10 g of bulbs of thunberg fritillary, 6 g-10 g of Chinese honeylocust spines, 6 g-10 g of Indian iphigenia bulbs,12 g-15 g of red peony roots, 12 g-15 g of snakegourd roots, 12 g-15 g of rhizoma atractylodis, 12 g-15 g of amur corktree bark, 12 g-15 g of radix stephaniae tetrandrae,12 g-15 g of oriental waterplantain rhizomes, 12 g-15 g of radix cyathulae, 4 g-6 g of frankincense, 4 g-6 g of myrrh, 4 g-6 g of liquorice and 3 g-5 g of pangolins. The traditional Chinese medicine preparation for preventing acute attack of the gouty arthritis has a remarkable curative effect, and clinical tests prove that the preparation has no toxic or side effects, is high in curative ratio, low in treatment cost, low in recurrence rate and suitable for being applied and popularized.

Description

A kind of Chinese medicine preparation treating gouty arthritis acute attack
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, particularly relate to a kind of Chinese medicine preparation treating gouty arthritis acute attack.
Background technology
Gout be purine metabolic disturbance and (or) one group of metabolic disease caused by underexcretion.Gouty arthritis is the initial and modal clinical manifestation of most of patient with gout.Primary disease onset is older many at about 40 years old, male is common,, there is the feature of outbreak and violent arthralgia swelling suddenly acute stage, the arthritis of most of patients shows as outbreak and alleviates alternately, course of disease elder's stage of attack length and the catabasis short, the even protracted course of disease having, shows chronic gout, stone gout.In recent years, along with the change day by day improved with dietary structure of living standard, the sickness rate of gouty arthritis substantially rises, and has the trend of rejuvenation gradually, is one of clinical difficult treatment.
Gouty arthritis is that urate crystal is deposited in synovium of joint, synovial bursa, cartilage and hetero-organization thereof the repeated relapsing diseases associated with inflammation caused.This disease is higher at American-European countries's sickness rate, in the past more rare in China.But improving along with living standards of the people and treatment level improves, its sickness rate has and increases trend..
But, the medicine such as modern medicine application colchicine can control acute symptom quickly, but because its side effect is big, and primary disease can not be cured, patient is often difficult to adhere to treatment, therefore relapse rate is also significantly high, so, people seek Chinese medicine more and more
Therefore, invent a kind of Chinese medicine preparation treating gouty arthritis acute attack and seem very necessary.
Summary of the invention
In order to solve above-mentioned technical problem, the present invention provides a kind of Chinese medicine preparation treating gouty arthritis acute attack, and to solve existing treatment gouty arthritis acute attack medicine, to there is side effect big, and can not cure primary disease, patient is often difficult to adhere to treating, therefore the problem that relapse rate is also significantly high.A kind of Chinese medicine preparation treating gouty arthritis acute attack includes the crude drug of following parts by weight: Radix Angelicae Sinensis 6g～10g, Pericarpium Citri Reticulatae 6g～10g, Bulbus Fritillariae Thunbergii 6g～10g, Spina Gleditsiae 6g～10g, Pseudobulbus Cremastrae Seu Pleiones 6g～10g, Radix Paeoniae Rubra 12g～15g, Radix Trichosanthis 12g～15g, Rhizoma Atractylodis 12g～15g, Cortex Phellodendri 12g～15g, Bi 12g～15g, Rhizoma Alismatis 12g～15g, Radix Cyathulae 12g～15g, Olibanum 4g～6g, Myrrha 4g～6g, Radix Glycyrrhizae 4g～6g, Squama Manis 3g～5g.
Preferably, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug of following parts by weight: Radix Angelicae Sinensis 10g～15g, Pericarpium Citri Reticulatae 10g～15g, Bulbus Fritillariae Thunbergii 10g～15g, Spina Gleditsiae 10g～15g, Pseudobulbus Cremastrae Seu Pleiones 10g～15g, Radix Paeoniae Rubra 15g～20g, Radix Trichosanthis 15g～20g, Rhizoma Atractylodis 15g～20g, Cortex Phellodendri 15g～20g, Bi 15g～20g, Rhizoma Alismatis 15g～20g, Radix Cyathulae 15g～20g, Olibanum 6g～8g, Myrrha 6g～8g, Radix Glycyrrhizae 6g～8g, Squama Manis 5g～8g.
Preferably, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug optimum ratio of following parts by weight: each 10g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 15g of Radix Cyathulae, Olibanum, Myrrha, each 6g of Radix Glycyrrhizae, Squama Manis 5g.
Preferably, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug optimum ratio of following parts by weight: each 6g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 12g of Radix Cyathulae, Olibanum, Myrrha, each 4g of Radix Glycyrrhizae, Squama Manis 3g.
Preferably, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug optimum ratio of following parts by weight: each 15g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 20g of Radix Cyathulae, Olibanum, Myrrha, Radix Glycyrrhizae, each 8g of Squama Manis.
Preferably, the Chinese medicine preparation employing decocting of described treatment gouty arthritis acute attack takes orally, every day 1 dose, decocts 2 juice, and point morning, late 2 decoction being taken warmly, 7 days be 1 course for the treatment of.
Preferably, the Chinese medicine preparation of described treatment gouty arthritis acute attack adopts Xian fang Huoming Yin plus-minus.Described Xian fang Huoming Yin comes from " school note married woman's good recipe ", there is heat-clearing and toxic substances removing, relieving swelling and disintegrating mass, blood circulation promoting and blood stasis dispelling, effect of regulating QI to relieve pain, Xian fang Huoming Yin aims at excess-heat skin infection and sets, and because the party's prescription is rigorous, compatibility is precise and appropriate, blood circulation promoting and blood stasis dispelling and just do not hinder, mass dissipating and swelling eliminating dredging collateral row is stagnant and not impairment of YIN, and all medicines share Wen Liang and offset, and the power that only row dissipates is distinguished.
Preferably, the Chinese medicine preparation of described treatment gouty arthritis acute attack take medicine after points for attention: focus on conditioning diet, limit greasy and surfeit flavour, give up alcohol, coffee, seafood, pluck and acidic food, diet should be light；Drink more water, increase the excretion of the turbid poison of uric acid；Obese patient should lose weight, and keeps moderate body weight.
Motherland's medical science also has the name of disease of " gout ", such as ZHU Dan-xi " Further Discourses on the Properties of Things " the just once special section of row gout, also corresponds to the diseases such as motherland's medical science " arthralgia aggravated by cold ", " severe and migratory arthralgia ", " beriberi ".Its etiology and pathogenesis successive dynasties, there was discussion in each family.ZHU Dan-xi " Further Discourses on the Properties of Things " carries: " gout person, big rate is heated self-boiling because of blood, thereafter or relate to cold water or vertical wetland ... cold and cool outer fight, and warm blood must be trembled with fear, and antiperspirant is turbid to stagnate, so having a pain, night then pain very, row is in the moon also ".Tang Wangtao " medical secrets of official " think primary disease " be the poison of wind and cold heat-damp in summer mostly, caused by void, mistake reason will be taken the photograph, by this ailment said due to cold or exposure; meridians knot is stagnant, stores between joint, or at extremity; its expectorant daytime is quiet and night is sent out, angor to the bone when sending out " " anxious then dump turbid poison, dampness removing blood stasis dispelling ".Owing to gouty arthritis main clinical manifestation is that pathological changes joint is red, swollen, hot, bitterly, moving obstacle, especially multiple with the first sole of the foot toe, instep or ankle joint, a part of patient, with heating, restlessness and thirst, red tongue, yellow fur, belongs to " pyretic arthralgia " or " arthralgia aggravated by cold " category in Chinese medicine numbness disease by its syndrome analysis.Its etiology and pathogenesis thinks relevant with expectorant stasis of blood turbid damp pyretic toxicity more, greasy product or excessive drinking is grown due to surfeit delicious food, accumulate humidogene expectorant heat-transformation, the turbid bet of wet hot phlegm, numbness resistance joint meridians, cause that qi and blood circulation is not smooth, stagnation of QI and blood may bring about pain, so common sufficient, ankle joint is red, swollen, hot, pain shape, as do not healed for a long time, recurrent exerbation, can make joint bone destruction in various degree and dysfunction occur.This patient all has that knee is scorching hot to swell and ache, red tongue with yellow fur, the symptom such as stringy and rolling pulse.Except blood stasis with the traditional Chinese medical science " damp-heat arthralgia " very much like.
Squama Manis gas raw meat in the Chinese medicine preparation of described treatment gouty arthritis acute attack and alter, it is very careful that it walks the property altered, therefore can declare logical internal organs, implements meridians, thoroughly reaches pass key, and all blood clotting blood gathers for disease, all can open it;The Radix Angelicae Dahuricae, Radix Saposhnikoviae thoroughly reach battalion and defend, mass dissipating and swelling eliminating;Olibanum, Myrrha gas are fragrant, and perfume (or spice) can be walked to alter and benefaction, therefore energy promoting the circulation of blood dissipating blood stasis, promoting the circulation of QI dredging collateral, blood diarrhea due to disorder of QI then pain is from only;Radix Angelicae Sinensis, Radix Paeoniae Rubra promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain;Rhizoma Atractylodis, Semen Coicis invigorating spleen to remove dampness eliminating impediment;Blood stasis part must have a Fu Yang, thus with Flos Lonicerae, Radix Trichosanthis, Cortex Phellodendri clear it, Cortex Phellodendri is held concurrently dampness effect;Bulbus Fritillariae Uninbracteatae, the same use of Radix Trichosanthis, assist heat clearing away mass dissipating and swelling eliminating;Pericarpium Citri Reticulatae promoting of the circulation of QI and removing the obstruction in the collaterals, Compendium of Material Medica calls this product " then mend with tonic, then rush down with cathartic, then rise with Hydrargyri Oxydum Rubrum, then drop with dropping medicine ", and in side, the merit of promoting blood circulation and detumescence is strengthened in compatibility application;Radix Cyathulae blood circulation promoting and blood stasis dispelling, priming is descending;Pain very when, gaseous pulse must be anxious, therefore delays it with Radix Glycyrrhizae, and Radix Glycyrrhizae is held concurrently coordinating the actions of various ingredients in a prescription.Rhizoma Smilacis Glabrae is monarch drug, clearing away heat-damp and promoting diuresis the turbid descending, can enter network and search to pick and damp and hot accumulate poison.Bi is ministerial drug, separating clear and excreting turbid, has dehumidifying, removing toxic substances, profit function of joint.Pseudobulbus cremastrae seu pleiones is adjuvant drug, sweet in the mouth, micro-pungent, cold in nature, enters liver, spleen channel, has heat clearing away, removing toxic substances, detumescence, eliminating stagnation, reduces phlegm, the effect that short expectorant stagnation resolvation dissipates.Strengthen principal agent heat-clearing and toxic substances removing, the power of dispersing swelling and dissipating binds.All medicines share plays heat clearing and damp drying altogether, blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain.The described Chinese medicine preparation Pseudobulbus Cremastrae Seu Pleiones for the treatment of gouty arthritis acute attack, Semen Coicis heat-clearing and toxic substances removing, removing damp and turbid, two medicines all have increases the effect that uric acid is effectively drained, and Pseudobulbus Cremastrae Seu Pleiones can effectively alleviate gout outbreak containing colchicine.Research shows, Semen Plantaginis, Pseudobulbus cremastrae seu pleiones have certain uricotelism, Radix Gentianae Macrophyllae, Herba Lycopodii can release uric acid pain B%C, the Chinese medicine preparation of described treatment gouty arthritis acute attack selects this type of medicine can not only be effectively improved therapeutic effect, Control in recurring, also embodies the dialectical principle combined with treatment according to differentiation of diseases.
Compared with prior art, there is advantages that owing to a kind of Chinese medicine preparation treating gouty arthritis acute attack of the present invention is widely used in treatment gouty arthritis acute attack.The Chinese medicine preparation of the present invention clinical tests prove that, has no side effect, and cure rate is high, and evident in efficacy, treatment cost is low, and relapse rate is not high, is suitable for popularization and application.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
A kind of Chinese medicine preparation treating gouty arthritis acute attack includes the crude drug of following parts by weight: each 6g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 12g of Radix Cyathulae, Olibanum, Myrrha, each 4g of Radix Glycyrrhizae, Squama Manis 3g.
Embodiment 2
A kind of Chinese medicine preparation treating gouty arthritis acute attack includes the crude drug of following parts by weight: each 10g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 15g of Radix Cyathulae, Olibanum, Myrrha, each 6g of Radix Glycyrrhizae, Squama Manis 5g.
Embodiment 3
A kind of Chinese medicine preparation treating gouty arthritis acute attack includes the crude drug of following parts by weight: each 15g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 20g of Radix Cyathulae, Olibanum, Myrrha, Radix Glycyrrhizae, each 8g of Squama Manis.
Chinese medicine preparation employing decocting in the embodiment of the present invention takes orally, every day 1 dose, decocts 2 juice, and point morning, late 2 decoction being taken warmly, 7 days be 1 course for the treatment of；Chinese medicine preparation in the embodiment of the present invention take medicine after points for attention: focus on conditioning diet, limit greasy and surfeit flavour, give up alcohol, coffee, seafood, pluck and acidic food, diet should be light；Drink more water, increase the excretion of the turbid poison of uric acid；Obese patient should lose weight, and keeps moderate body weight.
Clinical efficacy is verified:
(1) clinical observation
The present invention is adopted to treat 80 example patients, wherein male 40 examples, female 40 example；The oldest person 65 years old, age reckling 21 years old.
(2) Therapeutic Method
Employing decocting takes orally, every day 1 dose, decocts 2 juice, and point morning, late 2 decoction being taken warmly, 7 days be 1 course for the treatment of.
(3) therapeutic outcome
In 80 example patients, how taking effect at 3-15 days after taking medicine, through 1 to 2 course for the treatment of, cure rate is 86%.
Clinical test results shows, Drug therapy gouty arthritis acute attack of the present invention effect is notable, clinical tests prove that, has no side effect, and cure rate is high, and evident in efficacy, treatment cost is low, and relapse rate is not high, is suitable for popularization and application.
Utilize technical solutions according to the invention, or those skilled in the art is under the inspiration of technical solution of the present invention, design similar technical scheme, and reach above-mentioned technique effect, all fall into protection scope of the present invention.

Claims (8)

1. the Chinese medicine preparation treating gouty arthritis acute attack, it is characterized in that, the Chinese medicine preparation of this treatment gouty arthritis acute attack includes the crude drug of following parts by weight: Radix Angelicae Sinensis 6g～10g, Pericarpium Citri Reticulatae 6g～10g, Bulbus Fritillariae Thunbergii 6g～10g, Spina Gleditsiae 6g～10g, Pseudobulbus Cremastrae Seu Pleiones 6g～10g, Radix Paeoniae Rubra 12g～15g, Radix Trichosanthis 12g～15g, Rhizoma Atractylodis 12g～15g, Cortex Phellodendri 12g～15g, Bi 12g～15g, Rhizoma Alismatis 12g～15g, Radix Cyathulae 12g～15g, Olibanum 4g～6g, Myrrha 4g～6g, Radix Glycyrrhizae 4g～6g, Squama Manis 3g～5g.
2. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterized in that, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug of following parts by weight: Radix Angelicae Sinensis 10g～15g, Pericarpium Citri Reticulatae 10g～15g, Bulbus Fritillariae Thunbergii 10g～15g, Spina Gleditsiae 10g～15g, Pseudobulbus Cremastrae Seu Pleiones 10g～15g, Radix Paeoniae Rubra 15g～20g, Radix Trichosanthis 15g～20g, Rhizoma Atractylodis 15g～20g, Cortex Phellodendri 15g～20g, Bi 15g～20g, Rhizoma Alismatis 15g～20g, Radix Cyathulae 15g～20g, Olibanum 6g～8g, Myrrha 6g～8g, Radix Glycyrrhizae 6g～8g, Squama Manis 5g～8g.
3. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterized in that, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug optimum ratio of following parts by weight: each 10g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 15g of Radix Cyathulae, Olibanum, Myrrha, each 6g of Radix Glycyrrhizae, Squama Manis 5g.
4. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterized in that, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug optimum ratio of following parts by weight: each 6g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 12g of Radix Cyathulae, Olibanum, Myrrha, each 4g of Radix Glycyrrhizae, Squama Manis 3g.
5. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterized in that, the Chinese medicine preparation of described treatment gouty arthritis acute attack includes the crude drug optimum ratio of following parts by weight: each 15g of Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Pseudobulbus Cremastrae Seu Pleiones, Radix Paeoniae Rubra, Radix Trichosanthis, Rhizoma Atractylodis, Cortex Phellodendri, Bi, Rhizoma Alismatis, each 20g of Radix Cyathulae, Olibanum, Myrrha, Radix Glycyrrhizae, each 8g of Squama Manis.
6. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterised in that the Chinese medicine preparation of described treatment gouty arthritis acute attack adopts decocting to take orally, every day 1 dose, decocting 2 juice, point morning, late 2 decoction being taken warmly, 7 days be 1 course for the treatment of.
7. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterised in that the Chinese medicine preparation of described treatment gouty arthritis acute attack adopts Xian fang Huoming Yin plus-minus.
8. the Chinese medicine preparation treating gouty arthritis acute attack as claimed in claim 1, it is characterized in that, the Chinese medicine preparation of described treatment gouty arthritis acute attack take medicine after points for attention: focus on conditioning diet, restriction greasy and surfeit flavour, give up alcohol, coffee, seafood, pluck and acidic food, diet should be light；Drink more water, increase the excretion of the turbid poison of uric acid；Obese patient should lose weight, and keeps moderate body weight.
CN201610156745.6A 2016-03-21 2016-03-21 Traditional Chinese medicine preparation for preventing acute attack of gouty arthritis Pending CN105748927A (en)

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CN106692787A (en) * 2017-02-28 2017-05-24 云南省中医医院 Traditional Chinese medicine preparation for treating acute gouty arthritis and preparation method thereof
CN107517769A (en) * 2017-10-17 2017-12-29 四川华胜农业股份有限公司 A kind of Kiwi berry nursery soil formula and preparation method thereof
CN108992599A (en) * 2017-06-07 2018-12-14 徐定清 A kind of medicine pill for the Allopurinol that dehumidifies
CN112057587A (en) * 2020-10-14 2020-12-11 深圳市福田区妇幼保健院 Traditional Chinese medicine composition for gout and preparation method, external medicine and application thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106692787A (en) * 2017-02-28 2017-05-24 云南省中医医院 Traditional Chinese medicine preparation for treating acute gouty arthritis and preparation method thereof
CN108992599A (en) * 2017-06-07 2018-12-14 徐定清 A kind of medicine pill for the Allopurinol that dehumidifies
CN107517769A (en) * 2017-10-17 2017-12-29 四川华胜农业股份有限公司 A kind of Kiwi berry nursery soil formula and preparation method thereof
CN112057587A (en) * 2020-10-14 2020-12-11 深圳市福田区妇幼保健院 Traditional Chinese medicine composition for gout and preparation method, external medicine and application thereof

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