CN105748514A - 用于治疗肝脏疾病的间叶干细胞 - Google Patents

用于治疗肝脏疾病的间叶干细胞 Download PDF

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Publication number
CN105748514A
CN105748514A CN201610006180.3A CN201610006180A CN105748514A CN 105748514 A CN105748514 A CN 105748514A CN 201610006180 A CN201610006180 A CN 201610006180A CN 105748514 A CN105748514 A CN 105748514A
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CN
China
Prior art keywords
mscs
cona
hepatitis
disease
liver
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Pending
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CN201610006180.3A
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English (en)
Chinese (zh)
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洪士杰
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Individual
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Individual
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Publication of CN105748514A publication Critical patent/CN105748514A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201610006180.3A 2015-01-05 2016-01-05 用于治疗肝脏疾病的间叶干细胞 Pending CN105748514A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562099736P 2015-01-05 2015-01-05
US62/099,736 2015-01-05

Publications (1)

Publication Number Publication Date
CN105748514A true CN105748514A (zh) 2016-07-13

Family

ID=56342329

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610006180.3A Pending CN105748514A (zh) 2015-01-05 2016-01-05 用于治疗肝脏疾病的间叶干细胞

Country Status (3)

Country Link
JP (1) JP6898706B2 (ja)
CN (1) CN105748514A (ja)
TW (1) TWI740812B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108904533A (zh) * 2018-07-04 2018-11-30 卡替（上海）生物技术股份有限公司 牙髓间充质干细胞在制备肝硬化治疗药物中的用途
CN109996550A (zh) * 2016-12-22 2019-07-09 日本乐敦制药株式会社 非酒精性脂肪肝炎治疗剂和非酒精性脂肪肝炎治疗用试剂盒

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201804307WA (en) * 2015-11-24 2018-06-28 Rohto Pharmaceutical Co Ltd Therapeutic agent for liver disease containing stromal cells derived from adipose tissue and method for producing the same
EP3677289A4 (en) 2017-08-30 2020-08-26 FUJIFILM Corporation ANGIOGENIC AGENT AND PROCESS FOR THE PRODUCTION OF THE LATTER
EP3677287B1 (en) 2017-08-30 2024-05-29 FUJIFILM Corporation Cell transplantation device and method for manufacturing same
WO2020184425A1 (ja) * 2019-03-08 2020-09-17 国立大学法人新潟大学 マクロファージの誘導方法、抗炎症性マクロファージの誘導剤及び医薬組成物
CN113980896B (zh) * 2021-10-27 2023-10-20 中国人民解放军军事科学院军事医学研究院 Irf1在调控间充质干细胞免疫调节作用及产品上的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10047345B2 (en) * 2012-02-13 2018-08-14 Gamida-Cell Ltd. Culturing of mesenchymal stem cells with FGF4 and nicotinamide
KR101532556B1 (ko) * 2012-09-03 2015-06-30 메디포스트(주) 간엽줄기세포의 배양 방법
CN109576217A (zh) * 2012-12-14 2019-04-05 罗格斯新泽西州立大学 调节干细胞的免疫调节作用的方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JUN YU等: "Hypoxia preconditioned bone marrow mesenchymal stem cells promote liver regeneration in a rat massive hepatectomy model", 《STEM CELL RESEARCH & THERAPY》 *
NORIHITO KUBO等: "Efficacy of adipose tissue-derived mesenchymal stem cells for fulminant hepatitis in mice induced by concanavalin A", 《JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY》 *
马杰 等: "骨髓间充质干细胞治疗ConA诱导的小鼠急性肝损伤的有效性研究", 《中国实验血液学杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109996550A (zh) * 2016-12-22 2019-07-09 日本乐敦制药株式会社 非酒精性脂肪肝炎治疗剂和非酒精性脂肪肝炎治疗用试剂盒
CN108904533A (zh) * 2018-07-04 2018-11-30 卡替（上海）生物技术股份有限公司 牙髓间充质干细胞在制备肝硬化治疗药物中的用途

Also Published As

Publication number Publication date
JP2016138092A (ja) 2016-08-04
TWI740812B (zh) 2021-10-01
JP6898706B2 (ja) 2021-07-07
TW201709915A (zh) 2017-03-16

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Application publication date: 20160713