CN105726579A - Venenum bufonis composition, mosquito and insect repellent preparation containing venenum bufonis composition, preparation method and application of same - Google Patents
Venenum bufonis composition, mosquito and insect repellent preparation containing venenum bufonis composition, preparation method and application of same Download PDFInfo
- Publication number
- CN105726579A CN105726579A CN201610182654.XA CN201610182654A CN105726579A CN 105726579 A CN105726579 A CN 105726579A CN 201610182654 A CN201610182654 A CN 201610182654A CN 105726579 A CN105726579 A CN 105726579A
- Authority
- CN
- China
- Prior art keywords
- venenum bufonis
- mosquito
- preparation
- compositions
- mosquito dispersing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Catching Or Destruction (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides a venenum bufonis composition, mainly prepared from venenum bufonis and white wine by mixing, wherein the usage of venenum bufonis per 1 jin white wine is 1-5ml, and the alcohol content of the white wine is controlled at 25-30%vol. The invention also provides a mosquito and insect repellent preparation containing the venenum bufonis composition, mainly prepared from the following raw materials in parts by mass: 50-70 parts of venenum bufonis composition, 20-40 parts of flower and grass extracts and 5-15 parts of deodorant. The preparation method of the mosquito and insect repellent preparation comprises the step of mixing and stirring all the raw materials uniformly at a temperature condition of 20-30DEG C. The mosquito and insect repellent preparation is easy to use and can be directly coated or sprayed onto a body or insect bite to achieve the effects of repelling mosquito and insects, diminishing inflammation and easing pain.
Description
Technical field
The present invention relates to mosquito dispersing medicament preparation field, in particular to a kind of Venenum Bufonis compositions,
Mosquito dispersing preparation comprising this Venenum Bufonis compositions and preparation method thereof, application.
Background technology
Current research shows that mosquito main harm is to spread disease, it was found that the disease of mosquitoes spread reaches
More than kind more than 80.On earth, then do not have which kind of insecticide to have bigger compromising to the mankind than mosquito；
Mosquito in the world has kind more than 2,000, and China there are about kind more than 140, can divide three by pathophorous mosquito
Class a: class is anopheles, popular name malarial mosquito, main propagation malaria；Another kind of it is culex, main propagation silk
Parasitosis and epidemic encephalitis type B；3rd class, yellow-fever mosquito, has black and white speckle with it, cries again black speck mosquito,
Main propagation epidemic encephalitis type B and dengue fever, what mosquito was the most malicious is exactly its saliva, and they are mosquito
The pectoralis major (mosquito also has muscle) of son is grown, is then propagated by saliva, if itself bites
Your mosquito does not carry virus, then simply can be played bag after mosquito bite and itch, this is to get stung by
The anaphylaxis that mosquito saliva is produced by the person of stinging.If but in the saliva of mosquito, carry virus, then
Regardless of whether mosquito is hit to death, all can be infected.Just because of mosquito has the biggest harm, people
The method that have also been invented a lot of anophelifuge.
At present, anophelifuge method conventional on the market has following several: 1, do environmental health well, mosquito
Survival and reproduction environment must have water, and family hydrops to be removed, sewage are to utterly destroy the life of mosquito
Deposit space；2, grow tender of the crowd of faintly acid body constitution due to mosquito especially, therefore can improve body constitution,
Edible base-forming food and medicine, body constitution and blood are alkalescence, and mosquito is not liked to bite；3, sleep night
Mosquito net, anophelifuge lamp, electric mosquito flap etc. can be used during dormancy, avoid daytime the place mosquito is many to live as far as possible
Dynamic；4, essential balm anophelifuge: put a few box in bedroom and open menthocamphorate or the essential balm of lid, can be with anophelifuge；
5, Chinese red bulb is installed: owing to mosquito fears the light of Chinese red, so good anophelifuge can be produced
Effect.Without Chinese red bulb, it is also possible to the orange cellophane that light transmission is strong is enclosed within bulb.
But the above anophelifuge method opposing force is more weak, it is impossible to effectively realize mosquito dispersing,
Also have medicament when using floral water to be easy to volatilization, can gradually make mosquito create adaptability thus produce
Drug resistance.
In view of this, the special proposition present invention.
Summary of the invention
The first object of the present invention is to provide a kind of Venenum Bufonis compositions, and described Venenum Bufonis compositions has
Removing toxic substances, pain relieving, refreshment of having one's ideas straightened out, the effect of effective anophelifuge.
The second object of the present invention is to provide the mosquito dispersing preparation comprising above-mentioned Venenum Bufonis compositions, this system
What agent was creative contains Venenum Bufonis compositions, has abandoned the anophelifuge mode that conventional relativity is more weak,
Achieve effective anophelifuge and there are certain pain relieving, the effect of antiinflammatory in the injury to mosquito bite, be one
Lift two to obtain.
The third object of the present invention is to provide the preparation method of this mosquito dispersing preparation, the method preparation side
Method is simple, easy to operate, can completely retain the active ingredient of each raw material of mosquito dispersing preparation itself, operation
Condition is the gentleest.
The fourth object of the present invention is to provide the application of this mosquito dispersing preparation a kind of, and method is simple, should
With extensively, except with anophelifuge other insects can also be had good preventive effect, and after being bitten also
Having certain antiinflammatory, analgesic effect, purposes is powerful.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
The invention provides a kind of Venenum Bufonis compositions, mainly formed with Chinese liquor mixture by Venenum Bufonis, the most often
The consumption of jin Chinese liquor mixture Venenum Bufonis is 1-5ml, and the alcoholic strength of Chinese liquor controls between 25-30%vol.
Ear rear gland that Venenum Bufonis is the Bufo siccuss such as animal Bufonidae Bufo siccus or Bufo melanostictus and glandular integumentaria
The goods that secreted white serosity is processed, originate in national most area, concrete extracting method
For: Xia Qiu catches Bufo siccus, cleans body surface, after removing earth and impurity, with angle cutter scraping ear rear gland and
In in glandular integumentaria, the white serosity of secretion is placed in disk (never ironware, in order to avoid blackening), by stock white
Liquid is collected in a container, and the consumption of the Venenum Bufonis of the such as present invention probably controls between 1-5ml,
So need to scrape the Bufo siccus of more than thousand.
Venenum Bufonis property of medicine sweet, acrid, warm own, poisonous, return lung, liver, spleen, stomach warp, have relieve internal heat anti-
Cancer, the slow pain of detumescent, effect of eliminating carbuncle eliminating stagnation, pain relieving, heart tonifying also have certain curative effect, especially to anticancer
Its Ester being shown experimentally that in Venenum Bufonis to sarcoma180, rabbit BP tumor, cervical cancer 14,
Ascitic type liver cancers etc. all have inhibitory action.Lower jaw undifferentiated carcinoma, mesothelium on the cheekbone of people can be suppressed at body
The breathing of the tumor cells such as cancer, gastric cancer, sarcoma of spleen, hepatoma.Extend and suffer from spermocytoma, ehrlich ascites carcinoma
With the life cycle of liver cancer mouse, test tube has inhibitory action to leukaemia.The most visible Venenum Bufonis is many
For as used by cardiac tonic or curing cancers, the patent medicine of existing main circulation on the market have LIUSHEN WAN,
Chansu Wan, Venenum Bufonis analgesia ointment etc..
The present invention by the substantial amounts of biotoxin that experimental studies have found that in Venenum Bufonis except prior art is taken off
Outside the conventional drug effect shown, mosquito dispersing is also had good effect, and the injury of mosquito bite is had pain relieving,
The effect of antiinflammatory, and the Venenum Bufonis of low dose itself does not has any injury to the person.The present invention is just
Make use of this characteristic of Venenum Bufonis, itself and Chinese liquor are carried out mixture and obtains Venenum Bufonis compositions, should be noted that
Must be that Venenum Bufonis carries out mixture with Chinese liquor, if it is unallowed for using other drinks or solvent, because of
The drug effect of Venenum Bufonis itself well could be neutralized for only Chinese liquor so that it is drug effect performs to ultimate attainment, separately
Proportioning between the number of degrees of outer Chinese liquor, Chinese liquor and Venenum Bufonis is to need to control in suitable scope, this
Individual operating parameter is also that inventor passes through great many of experiments to determine, Venenum Bufonis joined by such as every 500ml Chinese liquor
Consumption be 1-5ml because the poisonous therefore dosage of Venenum Bufonis itself can not be too big, but if consumption is the least
Contained effective ingredient can not reach the purpose of mosquito dispersing very little, and the most most suitable proportioning consumption is
The Venenum Bufonis of Chinese liquor mixture 1-5ml per jin, such consumption both can guarantee that drug effect also ensure that safety,
Additionally the alcoholic strength of Chinese liquor controls between 25-30%vol, can during the highest subsequent applications of the number of degrees of Chinese liquor
Can have certain injury to the person, the number of degrees of Chinese liquor are the lowest may not have again corresponding effect,
Therefore the Chinese liquor number of degrees want suitable.It is furthermore preferred that the consumption of every 500ml Chinese liquor mixture Venenum Bufonis is 2-3ml,
The consumption of Chinese liquor mixture Venenum Bufonis the most per jin can be 1.5ml, 2.5ml, 3.5ml, 4ml and 4.5ml
Deng, between also the alcoholic strength of Chinese liquor is more excellent for 26-28%vol, can also be such as 25.5%vol,
26.5%vol, 27.5%vol, 28.5%vol, 29.5%vol etc..
The present invention, except providing the formula of this Venenum Bufonis compositions, additionally provides and comprises this Venenum Bufonis compositions
Mosquito dispersing preparation, mainly prepared by following raw material: in terms of volume parts, Venenum Bufonis compositions 50-70
Part, flowers and plants extract 20-40 part, eliminating smell agent 5-15 part.
The mosquito dispersing preparation of the embodiment of the present invention except comprising Venenum Bufonis compositions, also flowers and plants extract,
Eliminating smell agent is arranged in pairs or groups mutually, and flowers and plants extract includes Flos Jasmini Sambac, Flos Rosae Rugosae, Bulbus Lilii, Paeonia suffruticosa, Magnolia denudata
And one or more the mixed extraction gained in Flos Osmanthi Fragrantis, this extract is taken from flowers and plants, plant etc.
The flower of itself, leaf, root, bark, fruit, seed, resin etc. extract with distillation, squeezing mode
Coming, volatility is high, and molecule is little, it is easy to is absorbed by the body, and can permeate rapidly people's intracorporeal organ,
Unnecessary composition is excreted, and the fragrance of flowers and plants itself can also balance the taste of Venenum Bufonis, and energy
Play the secretion of Stimulation of The Brain pendant, ferment and hormone secretion etc., function in balanced body, additionally it is possible to
Play the effect of certain beauty and skin care.Eliminating smell agent can include talcum powder, skin care oil, quintessence oil, liquid distilled from honeysuckle flowers or lotus leaves
One of which in water, primarily serves the purpose of taste removal and neutralizes, improve the merit of the texture of mosquito dispersing preparation itself
Effect.
Preferably, in terms of volume parts, Venenum Bufonis compositions 55-65 part, flowers and plants extract 25-35 part,
Eliminating smell agent 8-12 part is more excellent for Venenum Bufonis compositions 60 parts, flowers and plants extract 30 parts, eliminating smell agent 10
Part, Venenum Bufonis compositions can also be 51 parts, 52 parts, 53 parts, 54 parts, 56 parts, 57 parts and
58 parts, 61 parts, 62 parts, 63 parts, 66 parts etc., flowers and plants extract can also be 21 parts, 22 parts,
23 parts, 26 parts, 31 parts, 33 parts and 34 parts etc., eliminating smell agent can also be 6 parts, 7 parts, 9
Part, 11 parts etc..
Noticeable being, each component in the mosquito dispersing preparation of the present invention is all that inventor is crowd
Carrying out choosing carefully for effect in the most existing material and obtain, each component is for the product of the present invention
Being specific for product, consumption is also required to carry out dispensing in strict accordance with the method for the present invention, because only that
The mosquito dispersing formulation products combined with the specific components of the present invention just has the merit of good mosquito dispersing
Effect, can lack by the efficacy exertion of each raw material such as Venenum Bufonis compositions, flowers and plants extract to ultimate attainment
Any component does not all reach such effect, and inventor is exactly based on the reasonable selection to each raw material
And compatibility so that the product effect of the mosquito dispersing preparation of the present invention becomes apparent from, fast, persistently, than
More satisfactory.Additionally the product of the present invention has no side effect, and can reduce the discharge of the ammonia nitrogen to environment after using
Deng, reduce environmental pollution, to the mankind and environmentally friendly, environmental protection, will not be to environment and people
Class health has any infringement.
In raw material dosage, each consumption be all inventor through substantial amounts of creative work optimization,
Therefore, in the range of being preferably controlled in suitable addition, such as Venenum Bufonis compositions is as major ingredient addition originally
Body can be more relatively large, and flowers and plants extract and these compositions of eliminating smell agent itself belong to the essence extracted
China's material, highly enriched product or be adjuvant, dosage need not i.e. can reach the best effect too greatly,
As long as achieving the goal, therefore each raw material all has and preferably adds scope, it is impossible to dosage is too big also
Can not be the least, need strict control.
Further, exactly because anophelifuge mode of the prior art also exists many defects, parasite killing is such as used
Spray, mosquito can develop immunity to drugs, and have pollution, especially for child；With floral water originally
Body can quickly distribute, and mosquito can slowly adapt to, with the medicine for external use such as ethanol, iodine tincture itself without any anthelmintic
Effect；Kindle mosquito repellent incense or can only play with mosquito net and temporarily stop that mosquito suffers the effect stung；Use mosquito killing machine
Carrying inconvenience Deng equipment itself, be not appropriate for mosquito eradication at home and use, therefore the present invention is precisely in order to solve
Certainly many technical problems present in prior art, have invented a kind of mosquito dispersing comprising Venenum Bufonis compositions
Preparation, so can directly benumb mosquito so that it is dare not bite people, be particularly well-suited in child.Aobvious
Not having any relating in right this mosquito dispersing preparation prior art, the present invention still belongs to pioneering, can pass through
This mosquito dispersing preparation is used to resist by some viral source such as the zika viruses of killing propagation.
The present invention, except providing the formula of a kind of mosquito dispersing preparation, additionally provides this mosquito dispersing preparation
Preparation method, comprises the steps: all raw materials mix and blend under conditions of temperature is 20-30 DEG C
Uniformly, to obtain final product.
The preparation method of the mosquito dispersing preparation of the embodiment of the present invention is first various raw materials to be carried out mixing to stir
Mix, by Venenum Bufonis compositions is interpenetrated to becoming completely with adjuvants such as flowers and plants extract, eliminating smell agents
Integrally, thus to ensure the performance of follow-up use, and the preparation method of the present invention is simple to operate, clever
Living, inventor is also by repeatedly testing the preferably syntheti c route finally taked.
It addition, the rate controlled of mix and blend can not the soonest can not in 400-500rad/min, speed
Too slow, the too fast effective ingredient that can destroy in raw material of speed, speed is crossed and can not had mix homogeneously slowly
Effect, mixing time is preferably controlled in more than 20min, between preferably 40-50min, mixing time with
Stir speed (S.S.) controls preferably together in suitable scope, so that the properties of product of preparation reach optimum.
The mosquito dispersing preparation using method of the embodiment of the present invention is the most fairly simple, directly coats or is sprayed on body
Go up or bite and sentence mosquito dispersing, antiinflammatory, analgesia.Such as it is sprayed directly on to baby, it is not necessary to dry,
Can cover on the face baby further and be sprayed with the gauze of this agent, to prevent mosquito bite.Adult is the same
Can directly spray use.Avoid the when of spray spraying in eyes, because Venenum Bufonis is biotoxin.Can also be used with
In gynecological and dentistry, need if dentistry to gargle with rear clear water.
The mosquito dispersing preparation of the present invention is finally made finished product and is typically made the product of every bottle of net content 100 milliliters
Product, the content of every bottle of Venenum Bufonis, between 0.1-0.5%, is preferably contained in spray bottle, is so convenient for carrying
With sprinkling, going for the demand of different crowd, applicable crowd is the widest.
Compared with prior art, the invention have the benefit that
(1) what the Venenum Bufonis compositions of the embodiment of the present invention was creative carries out interworking by Venenum Bufonis and Chinese liquor, and
By finding that Venenum Bufonis itself also has good effect to mosquito dispersing, this characteristic is utilized it to be used with suitable
To reach removing toxic substances after the Chinese liquor interworking of amount, pain relieving, refreshment of having one's ideas straightened out, the purpose of effective anophelifuge, except having
Effect anophelifuge can also have antiinflammatory, antibacterial effect；
(2) the mosquito dispersing preparation of the embodiment of the present invention is except comprising Venenum Bufonis compositions, also includes that flowers and plants carry
Take the adjuvant such as thing, eliminating smell agent, because each component is specific for the product of the present invention,
Consumption is also required to carry out dispensing in strict accordance with the method for the present invention, because only that with specific group of the present invention
The mosquito dispersing formulation products of subassembly just has effect of good mosquito dispersing, can be combined by Venenum Bufonis
The efficacy exertion of each raw material such as thing, flowers and plants extract, to ultimate attainment, lack any component and all reaches
Less than such effect, inventor is exactly based on rationally selecting and compatibility each raw material so that this
The product effect of bright mosquito dispersing preparation becomes apparent from, fast, persistently, more satisfactory；
(3) preparation method of the mosquito dispersing preparation of the embodiment of the present invention is first to be mixed by various raw materials
Stirring, by interpenetrating adjuvants such as Venenum Bufonis compositions and flowers and plants extract, eliminating smell agents completely to becoming
It is integrated, thus to ensure the performance of follow-up use, and the preparation method of the present invention is simple to operate,
Flexibly, inventor is also by repeatedly testing the preferably syntheti c route finally taked.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but this area skill
Art personnel are it will be appreciated that the following example is merely to illustrate the present invention, and are not construed as limiting the present invention
Scope.Unreceipted actual conditions person in embodiment, the condition advised according to normal condition or manufacturer
Carry out.Agents useful for same or instrument unreceipted production firm person, being can be by commercially available purchase acquisition
Conventional products.
Embodiment 1
The preparation method of mosquito dispersing preparation is as follows:
1) the Bufo siccus clear water alive of cultivation is cleaned, after removing earth and impurity, extrude it with bamboo clip
Big pimple on eyebrow, in the white serosity of outflow is placed in disk (never ironware, in order to avoid blackening), will
White serosity is collected in a container, and the white serosity taking 1ml is the Chinese liquor of 25%vol with alcoholic strength
1 jin is uniformly mixed so as to obtain Venenum Bufonis compositions in glass container；
2) take Venenum Bufonis compositions 70ml, Flos Jasmini Sambac extract 20ml and talcum powder 5ml jointly to put into
In agitated kettle, room temperature mixing and stirring prepares product, and product specification is 100ml/ bottle, quality testing
Can form sale after qualified, selling market is wide, and being particularly suited for new born infant has very well
Mosquito dispersing effect.
Embodiment 2
The preparation method of mosquito dispersing preparation is as follows:
1) the Bufo siccus clear water alive of cultivation is cleaned, after removing earth and impurity, extrude it with bamboo clip
Big pimple on eyebrow, in the white serosity of outflow is placed in disk (never ironware, in order to avoid blackening), filter
After removing earth and impurity, white serosity is collected in a container, take white serosity and the wine of 5ml
Precision is that the Chinese liquor 1 jin of 30%vol is uniformly mixed so as to obtain Venenum Bufonis compositions in glass container；
2) Venenum Bufonis compositions 50ml, Flos Jasmini Sambac extract 40ml and talcum powder 15ml are taken common
Putting in agitated kettle, room temperature mixing and stirring, the rate controlled of stirring is in 400rad/min, stirring
Time be more than 20min, prepare product, product specification is 100ml/ bottle, after quality testing is qualified
Can form sale, selling market is wide, and being particularly suited for new born infant has good anophelifuge
Worm effect.
Embodiment 3
The preparation method of mosquito dispersing preparation is as follows:
1) the Bufo siccus clear water alive of cultivation is cleaned, after removing earth and impurity, extrude it with bamboo clip
Big pimple on eyebrow, in the white serosity of outflow is placed in disk (never ironware, in order to avoid blackening), filter
After removing earth and impurity, white serosity is collected in a container, take white serosity and the wine of 2ml
Precision is that the Chinese liquor 1 jin of 26%vol is uniformly mixed so as to obtain Venenum Bufonis compositions in glass container；
2) Venenum Bufonis compositions 55ml, Flos Rosae Rugosae extract 25ml and floral water 12ml are taken common
Putting in agitated kettle, room temperature mixing and stirring, the rate controlled of stirring is in 500rad/min, stirring
Time be more than 20min, prepare product, product specification is 100ml/ bottle, after quality testing is qualified
Can form sale, selling market is wide, and being particularly suited for new born infant has good anophelifuge
Worm effect.
Embodiment 4
The preparation method of mosquito dispersing preparation is as follows:
1) the Bufo siccus clear water alive of cultivation is cleaned, after removing earth and impurity, extrude it with bamboo clip
Big pimple on eyebrow, in the white serosity of outflow is placed in disk (never ironware, in order to avoid blackening), filter
After removing earth and impurity, white serosity is collected in a container, take white serosity and the wine of 3ml
Precision is that the Chinese liquor 1 jin of 28%vol is uniformly mixed so as to obtain Venenum Bufonis compositions in glass container；
2) take Venenum Bufonis compositions 65ml, Flos Jasmini Sambac extract and Magnolia denudata Desr. extract mixing 35ml with
And talcum powder 8ml puts in agitated kettle jointly, room temperature mixing and stirring, the rate controlled of stirring exists
450rad/min, the time of stirring is 40min, prepares product, and product specification is 100ml/ bottle, often
The content of bottle Venenum Bufonis is 0.1-0.5% (safe level), can form sale after quality testing is qualified,
Selling market is wide, and being particularly suited for new born infant has good mosquito dispersing effect.
Embodiment 5
The preparation method of mosquito dispersing preparation is as follows:
1) the Bufo siccus clear water alive of cultivation is cleaned, after removing earth and impurity, extrude it with bamboo clip
Big pimple on eyebrow, in the white serosity of outflow is placed in disk (never ironware, in order to avoid blackening), filter
After removing earth and impurity, white serosity is collected in a container, take white serosity and the wine of 3ml
Precision is that the Chinese liquor 1 jin of 28%vol is uniformly mixed so as to obtain Venenum Bufonis compositions in glass container；
2) Venenum Bufonis compositions 60ml, Flos Moutan extract 30ml and skin care oil 10ml are taken common
Putting in agitated kettle, room temperature mixing and stirring, the rate controlled of stirring is in 420rad/min, stirring
Time be 50min, prepare product, product specification is 100ml/ bottle, and the content of every bottle of Venenum Bufonis is
0.1-0.5% (safe level), can form sale after quality testing is qualified, selling market is wide,
It is particularly suited for new born infant and has good mosquito dispersing effect.
Experimental example 1
The mosquito dispersing preparation that each embodiment of the present invention 1-5 is prepared and commercially available floral water (comparative example 1)
All randomly choose 100 people to be suitable for, all after mosquito bite, use (in general 15min) at once,
Using method bites place for being sprayed on, and after using, 1min, 3min, 5min add up the pain relieving of itching that disappears
Number；In the number that 15min, 30min, 60min statistics redness disappears.The result obtained such as table 1
Shown in table 2.
Table 1 disappears analgesic effect of itching
| Embodiment | 1min | 3min | 5min |
| Embodiment 1 | 80 | 95 | 100 |
| Embodiment 2 | 81 | 97 | 100 |
| Embodiment 3 | 79 | 95 | 100 |
| Embodiment 4 | 82 | 98 | 100 |
| Embodiment 5 | 77 | 94 | 99 |
| Comparative example 1 | 20 | 25 | 26 |
Table 2 is subsided a swelling effect
| Embodiment | 15min | 30min | 60min |
| Embodiment 1 | 65 | 88 | 97 |
| Embodiment 2 | 67 | 90 | 98 |
| Embodiment 3 | 65 | 87 | 97 |
| Embodiment 4 | 68 | 92 | 99 |
| Embodiment 5 | 64 | 85 | 95 |
| Comparative example 1 | 12 | 14 | 15 |
Observing and found by the situation not processed after mosquito bite, being bitten rear pruritus unbearably, pruritus is lasting
More than 10min, red and swollen a few hours do not disappear, and the even several days having are difficult to disappear, and often scratch and also can
It is damaged to skin, causes skin infection inflammation.After using the mosquito dispersing preparation that the present invention provides, 5 minutes
The most just can disappear pain relieving of itching, and in 60min, red and swollen basic disappearance, does not stay any cicatrix, at somebody group's skin
Cut has and rubescent has inflammation, through using the mosquito dispersing preparation of the present invention that redness also can be made to disappear, says
The mosquito dispersing preparation of the bright present invention has pain relieving, the antipruritic and good result of antiinflammatory.With existing flower
Dew compares that to have the time of itching that the disappears short elimination effect that swells and ache obvious, does not recurs, is bitten the skin at position
Recover, and there is the advantages such as easy to use, with low cost.As can be seen from Table 1 and Table 2,
The mosquito dispersing preparation for treating effect that the present invention provides is notable.
Experimental example 2
The mosquito dispersing preparation embodiment of the present invention 1 prepared and floral water (comparative example 1) do as follows
Experiment: respectively the left hand of experimenter is sprayed the mosquito dispersing preparation that embodiments of the invention 1 prepare,
Right hand spraying decoration dew, then takes the transparent chest of two formed objects, and right-hand man puts in two thoroughly respectively
In bright chest, left hand stretches into the chest on the left side, and the right hand stretches into the chest on the right, difference thing in chest
It is initially charged with the mosquito that quantity is equal, by observing it is found that the chest never mosquito on the left side falls
On arm, but lie prone after tripping on chest sidewall, but in the chest on the right, within front 5min
Mosquito simply around turning, constantly has mosquito to fall on arm after 5min, can also from this experiment
The mosquito dispersing preparation going out the embodiment of the present invention has good repelling effect, and commercially available floral water is simply
The effect of temporary transient anophelifuge can be played, lasting effects can not be reached.
After the mosquito dispersing preparation of embodiment of the present invention 2-5 being tested by identical experiment method also
Obtain the effect identical with experimental example 2.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that and do not carrying on the back
May be made that in the case of the spirit and scope of the present invention many other change and amendment.Therefore,
This means all these changes including belonging in the scope of the invention in the following claims and repair
Change.
Claims (10)
1. a Venenum Bufonis compositions, it is characterised in that mainly formed with Chinese liquor mixture by Venenum Bufonis, wherein
The consumption of Chinese liquor mixture Venenum Bufonis per jin is 1-5ml, and the alcoholic strength of Chinese liquor controls between 25-30%vol.
Venenum Bufonis compositions the most according to claim 1, it is characterised in that Chinese liquor mixture toad per jin
Crisp consumption is 2-3ml.
3. according to the Venenum Bufonis compositions described in any one of claim 1-2, it is characterised in that described in vain
The alcoholic strength of wine controls at 26-28%vol.
4. comprise the mosquito dispersing preparation of Venenum Bufonis compositions described in any one of claim 1-3, its feature
It is, is mainly prepared by following raw material: in terms of volume parts, Venenum Bufonis compositions 50-70 part, flowers and plants
Extract 20-40 part, eliminating smell agent 5-15 part.
Mosquito dispersing preparation the most according to claim 4, it is characterised in that in terms of volume parts,
Venenum Bufonis compositions 55-65 part, flowers and plants extract 25-35 part, eliminating smell agent 8-12 part.
Mosquito dispersing preparation the most according to claim 4, it is characterised in that in terms of volume parts,
Venenum Bufonis compositions 60 parts, flowers and plants extract 30 parts, eliminating smell agent 10 parts.
7. according to the mosquito dispersing preparation described in any one of claim 4-6, it is characterised in that described remove
Taste agent includes the one of which in talcum powder, skin care oil, quintessence oil, floral water；
Preferably, described flowers and plants extract include Flos Jasmini Sambac, Flos Rosae Rugosae, Bulbus Lilii, Paeonia suffruticosa, Magnolia denudata and
One or more mixed extraction gained in Flos Osmanthi Fragrantis.
8. the preparation method of the mosquito dispersing preparation described in any one of claim 4-7, it is characterised in that
Comprise the steps:, by all raw materials mixing and stirring under conditions of temperature is 20-30 DEG C, to obtain final product.
The preparation method of mosquito dispersing preparation the most according to claim 8, it is characterised in that mixing
The rate controlled of stirring controls at more than 20min in 400-500rad/min, the time of mix and blend,
Preferably 40-50min.
10. according to the application of the mosquito dispersing preparation described in any one of claim 4-7, it is characterised in that
By this mosquito dispersing preparation directly with cotton swab coating or with being sprayed on or bite and sentence mosquito dispersing, antiinflammatory, town
Bitterly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610182654.XA CN105726579A (en) | 2016-03-28 | 2016-03-28 | Venenum bufonis composition, mosquito and insect repellent preparation containing venenum bufonis composition, preparation method and application of same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610182654.XA CN105726579A (en) | 2016-03-28 | 2016-03-28 | Venenum bufonis composition, mosquito and insect repellent preparation containing venenum bufonis composition, preparation method and application of same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105726579A true CN105726579A (en) | 2016-07-06 |
Family
ID=56253273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610182654.XA Pending CN105726579A (en) | 2016-03-28 | 2016-03-28 | Venenum bufonis composition, mosquito and insect repellent preparation containing venenum bufonis composition, preparation method and application of same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105726579A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214571A (en) * | 2016-08-29 | 2016-12-14 | 钟林邑 | A kind of Melia azedarach L. mosquito dispersing compositions and its preparation method and application |
| WO2018129702A1 (en) * | 2017-01-13 | 2018-07-19 | 史仅 | Medical device for preventing mosquito bite itching and zika and like viruses |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225276A (en) * | 1998-11-17 | 1999-08-11 | 梅唤群 | Drug for radical curing dental caries |
| CN102727529A (en) * | 2011-04-12 | 2012-10-17 | 杜万伟 | Radical treatment soup for Aids |
-
2016
- 2016-03-28 CN CN201610182654.XA patent/CN105726579A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225276A (en) * | 1998-11-17 | 1999-08-11 | 梅唤群 | Drug for radical curing dental caries |
| CN102727529A (en) * | 2011-04-12 | 2012-10-17 | 杜万伟 | Radical treatment soup for Aids |
Non-Patent Citations (2)
| Title |
|---|
| 吴汉斌: "六神药露的制备与疗效观察", 《时珍国药研究》 * |
| 苏洪林: "蟾酥方剂的制作", 《养殖技术顾问》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214571A (en) * | 2016-08-29 | 2016-12-14 | 钟林邑 | A kind of Melia azedarach L. mosquito dispersing compositions and its preparation method and application |
| CN106214571B (en) * | 2016-08-29 | 2020-06-02 | 钟林邑 | Melia azedarach mosquito-repellent composition and preparation method and application thereof |
| WO2018129702A1 (en) * | 2017-01-13 | 2018-07-19 | 史仅 | Medical device for preventing mosquito bite itching and zika and like viruses |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106562921A (en) | Liquid oral composition containing TCM active substances and tea tree essential oil | |
| CN111135209A (en) | Artemisia apiacea spray with effects of preventing malaria, repelling mosquitoes, relieving itching and repairing and preparation method thereof | |
| CN105726579A (en) | Venenum bufonis composition, mosquito and insect repellent preparation containing venenum bufonis composition, preparation method and application of same | |
| CN104985963A (en) | Novel stationery storage device compounded by tourmaline and activated carbon | |
| Drury | Tea Tree Oil: A medicine kit in a bottle | |
| CN107926248A (en) | Improve the fertilizing method of Bu Funa fruit senile-resistant efficacies | |
| CN106344453A (en) | Novel acne cream and preparation method thereof | |
| CN106577838A (en) | Preparation method of mosquito repellent liquid based on ten Chinese herbal medicines | |
| JPH02264663A (en) | Aromatic deodorant | |
| CN115607586A (en) | Application of dandelion and monomer compound thereof in mite killing | |
| KR101057017B1 (en) | Anti-hair loss soap containing natural extract | |
| Wróblewska et al. | Activity of Plant Essential Oils Against Demodex folliculorum and Demodex brevis | |
| CN109045029A (en) | A kind of purposes of imidazopyridine derivatives | |
| CN109432240A (en) | A kind of bamboo rat oil antipruritic powder poison cream and preparation method thereof | |
| KR102639350B1 (en) | Cosmetic composition for strengthening skin barrier comprising herbal extract, calendula extract and mink oil | |
| CN106619463A (en) | Moisture replenishing and retaining traditional Chinese medicinal mask, as well as preparation method and using method thereof | |
| CN108077336A (en) | A kind of injection drying agent for preventing canarium pimela tree pest and disease damage | |
| KR20120122109A (en) | Composition for treating hair or scalp to prevent hair loss and promote growing hair with Herb Extract | |
| CN106367241A (en) | Herbal skin care perfumed soap and preparation method thereof | |
| CN105687082A (en) | Shampoo capable of helping hair growth and blackening hair | |
| CN110613823A (en) | Traditional Chinese medicine composition for treating beriberi and bromhidrosis, preparation method thereof and medicine containing traditional Chinese medicine composition | |
| Kadam et al. | Biochemical analysis of leaves of some medicinal plants of Marathwada region in Maharashtra | |
| CN104924949A (en) | Dried lacquer healthcare type automobile supporting foot pad | |
| CN1628822A (en) | Chinese medicinal liquor for treating psoriasis and preparation method thereof | |
| US20240139273A1 (en) | Chinese herbal medicine anti-virus areca nut product and preparation method thereof, and areca nut additive agent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160706 |