CN105685759A - Effervescent tablets with lung heat clearing function and preparation method of effervescent tablets - Google Patents

Effervescent tablets with lung heat clearing function and preparation method of effervescent tablets Download PDF

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Publication number
CN105685759A
CN105685759A CN201610138972.6A CN201610138972A CN105685759A CN 105685759 A CN105685759 A CN 105685759A CN 201610138972 A CN201610138972 A CN 201610138972A CN 105685759 A CN105685759 A CN 105685759A
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extract
heat clearing
adds
lung heat
filtrate
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孙明军
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Nanjing Youneng Biotech Co Ltd
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Nanjing Youneng Biotech Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/40—Effervescence-generating compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/68—Acidifying substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses effervescent tablets with a lung heat clearing function. The effervescent tablets comprise components in percentage by mass as follows: 5%-15% of a grosvenor momordica fruit and boat-fruited scaphium seed mixed extract, 5%-8% of a fragrant solomonseal rhizome extract, 3%-8% of a semen arecae extract, 5%-10% of a green tea extract, 2%-5% of sodium alginate, 15%-25% of citric acid, 10%-15% of sodium bicarbonate, 10%-40% of lactose, 3% of fumaric acid, 1%-2% of steviol glycoside, 3% of polyvinylpyrrolidone and 0.5%-1% of food flavor. The invention further discloses a preparation method of the effervescent tablets. The lung heat clearing food suitable for the modern fast-paced life mode is invented in combination of multiple compatible edible and medicinal raw materials and effervescent tablets as modern preparations. The effervescent tablets have the advantages that the effervescent tablets are portable, are instantly taken once brewed, taste sweet and fresh and are easily accepted, do not have side effects on a human body, have the lung heat clearing effect, can prevent and relieve lung disease, and are quite beneficial to lung maintenance after long-term drinking.

Description

There is effervescent tablet of lung heat clearing function and preparation method thereof
Technical field
The invention belongs to food manufacture field, be specifically related to a kind of effervescent tablet with lung heat clearing function。
Background technology
Effervescent tablet be with suitable acid, alkali is for disintegrating agent and adds a kind of tablet that other raw material is made, put in water, there is violent chemical reaction in bronsted lowry acids and bases bronsted lowry, produce carbon dioxide, promoting a kind of novel troche that tablet disintegrate within the section time is dissolved, country GB/T29602-2013 " solid beverage " is to arrange it for specific type solid beverage。
Along with air-polluting aggravates, pulmonary and respiratory tract disease are in ascendant trend year by year, and wherein pulmonary carcinoma has become the cancer that China's fatality rate is the highest。For modern, it should pay attention to pulmonary's maintenance。
Summary of the invention
It is an object of the invention to provide a kind of effervescent tablet with lung heat clearing function。
The technical scheme is that and be accomplished by:
A kind of effervescent tablet with lung heat clearing function; by weight/mass percentage composition, comprise Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract 5-15%, Rhizoma Polygonati Odorati extract 5 ~ 8%, Semen Arecae extract 3 ~ 8%, green tea extract 5 ~ 10%, sodium alginate 2-5%, citric acid 15 ~ 25%, sodium bicarbonate 10 ~ 15%, lactose 10 ~ 40%, fumaric acid 3%, stevioside 1 ~ 2%, polyvinylpyrrolidone 3%, essence for food 0.5 ~ 1%。
The preparation method that present invention also offers the above-mentioned effervescent tablet with lung heat clearing function, its step includes:
A, decoction and alcohol sedimentation technique prepare Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract, Rhizoma Polygonati Odorati extract, Semen Arecae extract and green tea extract respectively；
After B, citric acid are pulverized; granulate with the alcoholic solution of PVP; sodium bicarbonate, sodium alginate, lactose, stevioside mixing PVP alcoholic solution granulate; above granule weighs according to quantity; and weigh Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract powder, Rhizoma Polygonati Odorati extract powder, Semen Arecae extract powder, green tea extract powder, add fumaric acid and essence for food mix homogeneously tabletting, packaging。
In described step A, Fructus Momordicae, Semen Sterculiae Lychnophorae add 6 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, add 95% ethanol alcohol and form sediment, concentrate, drying under reduced pressure powdering。
Further, in described step A, Rhizoma Polygonati Odorati adds 6 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Further, in described step A, Semen Arecae adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Further, in described step A, green tea adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Further, the alcoholic solution of described PVP is ethanol containing 3%PVP and the water volume mixture with 9:1。
The present invention, with the material combination of multiple medicine-food two-purpose, has invented the lung heat clearing food of a kind of applicable modern fast pace life style in conjunction with effervescent tablet this Modern preparations mode。The effervescent tablet of the present invention has easy to carry, and with bubble with drink, taste and sweet mouthfeel is salubrious, and human body is had no side effect, has the effect of lung heat clearing, can prevent and alleviate pulmonary disease by the advantage being willing to accept, and long-term drink is highly beneficial to pulmonary's maintenance。
Fructus Momordicae feeble QI, taste is sweet, has effect of clearing heat and moistening lung, laxation relieving constipation, for lung-fire cough caused by dryness, pharyngalgia aphonia, dryness of the intestine constipation。
Semen Sterculiae Lychnophorae is lightly seasoned micro-sweet, cool in nature, has heat clearing away, lung moistening, sore-throat relieving, effect of removing toxic substances。
Rhizoma Polygonati Odorati sweet in the mouth, flat, there is yin nourishing, lung heat clearing, moisturize, relieving restlessness, the effect quenched the thirst。
Semen Arecae bitter in the mouth is pungent, temperature, puckery, cures mainly all gas, for miasma of dispelling, broken stagnant gas, dissipating depression of QI gas, lower mental disorder, removes pneumatosis, solves legendary venomous insect gas, rapid digestion of food gas, discharging the water pathogen, dissipates the medicine of beriberi, parasite killing gas, logical upper gas, alleviating distention in middle-JIAO gas, diarrhea gas。The cool property of Fructus Momordicae, Semen Sterculiae Lychnophorae and green tea can be neutralized。
Green tea is considered as state's drink in China, having refreshes oneself clears away heart-fire, clearing away summer-heat, eliminate indigestion and phlegm, go greasy fat-reducing, the relieving restlessness that clears away heart-fire, removing toxic substances relieving alcoholic intoxication, promoting the production of body fluid to quench thirst, pathogenic fire reducing improving eyesight, dysentery relieving dehumidifying effect。
Sodium alginate is natural polysaccharide, there is stability, dissolubility, viscosity and safety, use as stabilizer, thickening agent, emulsifying agent, dispersant, gellant, fruit glaze agent, suspending agent at modern industry, it it is the indispensable a kind of dietary fiber of human body simultaneously, there is unique threpsology's function, can the harmful substance that sucked by lung of complexation, clean alveolar, reduce metabolic waste in blood, it is also possible to improve digestion and the absorption of nutrient substance。
Stevioside is a kind of glucosides extracted from the leaf of Folium Stevlae Rebaudianae, as a kind of safe and reliable non-nutritive sweetener, there is high sugariness, feature low in calories, its sugariness is 200-300 times of sucrose, and heat is only 1/the 300 of sucrose, through experimental results demonstrate, stevioside has no side effect, non-carcinogenesis, and can prophylaxis of hypertension, diabetes, obesity, dental caries etc., be the desirably generation sugar sweeting agent of a kind of natural origin。
In effervescent tablet, effervescent is citric acid and sodium bicarbonate, and violent chemical reaction occurs in water for citric acid and sodium bicarbonate, produces carbon dioxide, citric acid and the amount of sodium bicarbonate and the CO in effervescent tablet in certain volume water2Generation amount be directly proportional, the best aerogenesis of citric acid and sodium bicarbonate ratio is for 0.76:1, but now about aqueous ph value neutrality, mouthfeel is poor, and in order to adjust mouthfeel, the ratio of general citric acid and sodium bicarbonate is 0.9 ~ 1.7:1, and pH value is 4.5 ~ 5.0。CO2 is indispensable composition, CO in soda pop2Main Function in soda pop strengthens local flavor, moreover it is possible to bring, to people, mouthfeel of stopping。CO2Measuring more high, the reaction of effervescent tablet foaming effect is more violent。But while considering bubble effect, the sodium citrate produced in the beverage after also taking into account acid-base reaction, because sodium citrate can make beverage produce offending astringent taste, thus the aftertaste mouthfeel of beverage is produced important impact, therefore the consumption of citric acid and sodium bicarbonate is also unsuitable too high。Therefore citric acid of the present invention and the sodium bicarbonate consumption in effervescent tablet formula is sodium citrate 15 ~ 25%, sodium bicarbonate 10 ~ 15%。Bubbling acutely, the persistent period is longer。
Polyvinylpyrrolidone (PVP) is binding agent, convas tablet binding agent has PVP, sugar liquid, starch slurry, polyvinyl acetate copolymer, sodium carboxymethyl cellulose etc., the present inventor contrasts discovery by experiment, select sugar liquid as binding agent, dispensing citric acid powder is easily lumpd in granulation process, slow-drying, the dried granule also very easily moisture absorption。Selecting sodium carboxymethyl cellulose as binding agent, sodium carboxymethyl cellulose is difficult to dissolve at short notice, also easily lumps in pelletization, it is difficult to dries, is unsuitable for big production operation。PVP as binding agent, granule prevented from caking, dry rapidly, product dissolves rapidly。Therefore select 90% alcoholic solution containing 3%PVP as binding agent。
Fumaric acid is lubricant, the phenomenon such as during for avoiding industrialized production tablet weight fluctuation is big, sticking and slice difficulty, makes sheeting process be smoothed out, and granule must be added to lubricant before tabletting。Conventional lubricant has polyethylene glycol 6000, fumaric acid, sodium lauryl sulphate, silicon dioxide etc., although PEG6000 lubricity and resistance to bond are pretty good, but addition DeGrain below 3%, and foam during effervescent, can be produced, extend the effervescent time。Fumaric acid does not have hygroscopicity, and there is fabulous lubrication, fumaric acid itself is a kind of acid source, faintly acid, having salubrious tart flavour after dissolving, weak point is that water solublity is not as, and adds the fumaric acid tabletting of 3% and can be smoothed out, substantially without undissolved fumaric acid after effervescent, mouthfeel is salubriouser。Therefore selecting fumaric acid as the lubricant of effervescent tablet, mix with granule before tabletting, addition is 3%。
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited except as。
Embodiment 1:
The preparation method originally with the effervescent tablet of lung heat clearing effect:
1, producing extract: Fructus Momordicae 5 parts, Semen Sterculiae Lychnophorae 5 parts add 6 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering；
Rhizoma Polygonati Odorati adds 6 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Semen Arecae adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Green tea adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
2, granulating: after being pulverized by citric acid 15%, make granule with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%；Sodium bicarbonate 10%, lactose 39.5%, stevioside 1%, sodium alginate 2% are mixed, granule is made with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%, and making the content of polyvinylpyrrolidone in end-product is 3%。
3, tabletting: take above-mentioned two kinds of dry granules and mix homogeneously with Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract 5%, Rhizoma Polygonati Odorati extract 5%, Semen Arecae extract 6%, green tea extract 10%, Green tea essence 0.5% and fumaric acid 3%, enter tabletting machine, every 4 grams。
4, packaging: the effervescent tablet pressed is packed, 20 every bottle。
The effervescent tablet monolithic that the present invention makes weighs 4 grams, uniform color, and hardness is moderate, is dissolved in 200ml warm water or cold water, sour and sweet palatability, and CO2 is sufficient, mouthfeel of stopping, and has the Fructus Lycii fragrance of gentleness。And use through osteoporosis person, it was demonstrated that there is good lung heat clearing effect。
The effect of the effervescent tablet that above-described embodiment prepares is carried out efficacy detection, chooses more than one week patient of 30 example persistent cough, wherein male 11 example, women 19 example；At 30 50 years old age, every patient takes the effervescent tablet 3 ~ 5 of the embodiment of the present invention 1 every day, continues 20 days, and 26 example patients cough stoppings, and 2 example patients cough and alleviate。
Embodiment 2:
The preparation method originally with the effervescent tablet of lung heat clearing effect:
1, producing extract: Fructus Momordicae 9 parts, Semen Sterculiae Lychnophorae 1 part add 6 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering；
Rhizoma Polygonati Odorati adds 6 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Semen Arecae adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Green tea adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
2, granulating: after being pulverized by citric acid 25%, make granule with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%；Sodium bicarbonate 15%, lactose 15%, stevioside 2%, sodium alginate 5% are mixed, granule is made with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%, and making the content of polyvinylpyrrolidone in end-product is 3%。
3, tabletting: take above-mentioned two kinds of dry granules and mix homogeneously with Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract 10%, Rhizoma Polygonati Odorati extract 8%, Semen Arecae extract 8%, green tea extract 5%, Green tea essence 1% and fumaric acid 3%, enter tabletting machine, every 4 grams。
4, packaging: the effervescent tablet pressed is packed, 20 every bottle。
The effect of the effervescent tablet that above-described embodiment prepares is carried out efficacy detection, chooses more than one week patient of 30 example persistent cough, wherein male 18 example, women 12 example；At 30 50 years old age, every patient takes the effervescent tablet 3 ~ 5 of the embodiment of the present invention 1 every day, continues 20 days, and 27 example patients cough stoppings, and 3 example patients cough and alleviate。
Embodiment 3:
The preparation method originally with the effervescent tablet of lung heat clearing effect:
1, producing extract: Fructus Momordicae 5 parts, Semen Sterculiae Lychnophorae 5 parts add 6 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering；
Rhizoma Polygonati Odorati adds 6 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Semen Arecae adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Green tea adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
2, granulating: after being pulverized by citric acid 20%, make granule with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%；Sodium bicarbonate 12%, lactose 24.5%, stevioside 1.5%, sodium alginate 3.2% are mixed, granule is made with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%, and making the content of polyvinylpyrrolidone in end-product is 3%。
3, tabletting: take above-mentioned two kinds of dry granules and mix homogeneously with Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract 15%, Rhizoma Polygonati Odorati extract 6%, Semen Arecae extract 3%, green tea extract 8%, Green tea essence 0.8% and fumaric acid 3%, enter tabletting machine, every 4 grams。
4, packaging: the effervescent tablet pressed is packed, 20 every bottle。
The effect of the effervescent tablet that above-described embodiment prepares is carried out efficacy detection, chooses more than one week patient of 30 example persistent cough, wherein male 14 example, women 16 example；At 30 50 years old age, every patient takes the effervescent tablet 3 ~ 5 of the embodiment of the present invention 1 every day, continues 20 days, and 25 example patients cough stoppings, and 2 example patients cough and alleviate。
Embodiment 4:
The preparation method originally with the effervescent tablet of lung heat clearing effect:
1, producing extract: Fructus Momordicae 1 part, Semen Sterculiae Lychnophorae 9 parts add 6 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering；
Rhizoma Polygonati Odorati adds 6 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Semen Arecae adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
Green tea adds 8 times amount water reflux, extract, 3 times, each 1 hour, and extracting solution filters, and filtrate merges, and filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
2, granulating: after being pulverized by citric acid 25%, make granule with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%；Sodium bicarbonate 15%, lactose 10%, stevioside 2%, sodium alginate 4% are mixed, granule is made with 90% alcoholic solution containing 3% polyvinylpyrrolidone (PVP), with 40 mesh sieve granulate, at 50 DEG C, forced air drying is to water content < 3%, and making the content of polyvinylpyrrolidone in end-product is 3%。
3, tabletting: take above-mentioned two kinds of dry granules and mix homogeneously with Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract 15%, Rhizoma Polygonati Odorati extract 7.5%, Semen Arecae extract 5%, green tea extract 10%, Green tea essence 0.5% and fumaric acid 3%, enter tabletting machine, every 4 grams。
4, packaging: the effervescent tablet pressed is packed, 20 every bottle。
The effect of the effervescent tablet that above-described embodiment prepares is carried out efficacy detection, chooses more than one week patient of 30 example persistent cough, wherein male 15 example, women 15 example；At 30 50 years old age, every patient takes the effervescent tablet 3 ~ 5 of the embodiment of the present invention 1 every day, continues 20 days, and 26 example patients cough stoppings, and 3 example patients cough and alleviate。

Claims (7)

1. an effervescent tablet with lung heat clearing function; it is characterized in that by weight/mass percentage composition, comprise Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract 5-15%, Rhizoma Polygonati Odorati extract 5 ~ 8%, Semen Arecae extract 3 ~ 8%, green tea extract 5 ~ 10%, sodium alginate 2-5%, citric acid 15 ~ 25%, sodium bicarbonate 10 ~ 15%, lactose 10 ~ 40%, fumaric acid 3%, stevioside 1 ~ 2%, polyvinylpyrrolidone 3%, essence for food 0.5 ~ 1%。
2. a preparation method with the effervescent tablet of lung heat clearing function, its step includes:
A, decoction and alcohol sedimentation technique prepare Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract, Rhizoma Polygonati Odorati extract, Semen Arecae extract and green tea extract respectively；
After B, citric acid are pulverized; granulate with the alcoholic solution of PVP; sodium bicarbonate, sodium alginate, lactose, stevioside mixing PVP alcoholic solution granulate; above granule weighs according to quantity; and weigh Fructus Momordicae, Semen Sterculiae Lychnophorae mixed extract powder, Rhizoma Polygonati Odorati extract powder, Semen Arecae extract powder, green tea extract powder, add fumaric acid and essence for food mix homogeneously tabletting, packaging。
3. the preparation method of the effervescent tablet with lung heat clearing function according to claim 2, it is characterized in that: in described step A, Fructus Momordicae, Semen Sterculiae Lychnophorae add 6 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, filtrate merges, filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
4. the preparation method of the effervescent tablet with lung heat clearing function according to claim 2, it is characterized in that: in described step A, Rhizoma Polygonati Odorati adds 6 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, filtrate merges, filtrate is concentrated into relative density 1.15 ~ 1.20%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
5. the preparation method of the effervescent tablet with lung heat clearing function according to claim 2, it is characterized in that: in described step A, Semen Arecae adds 8 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, filtrate merges, filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
6. the preparation method of the effervescent tablet with lung heat clearing function according to claim 2, it is characterized in that: in described step A, green tea adds 8 times amount water reflux, extract, 3 times, each 1 hour, extracting solution filters, filtrate merges, filtrate is concentrated into relative density 1.10 ~ 1.15%, adds 95% ethanol alcohol and forms sediment, concentrates, drying under reduced pressure powdering。
7. the preparation method of the effervescent tablet with lung heat clearing function according to any one of claim 2-6, it is characterised in that: the alcoholic solution of described PVP is ethanol containing 3%PVP and the water volume mixture with 9:1。
CN201610138972.6A 2016-03-13 2016-03-13 Effervescent tablets with lung heat clearing function and preparation method of effervescent tablets Pending CN105685759A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1088393A (en) * 1992-12-24 1994-06-29 沈在中 The processing method of tea of throat care
CN103907707A (en) * 2014-03-14 2014-07-09 南京融点食品科技有限公司 Grosvenor-momordica-fruit lung-clearing tea and preparation method thereof
CN105381019A (en) * 2015-11-19 2016-03-09 南京优能生物科技有限公司 Effervescent tablet with internal-fire clearing function and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1088393A (en) * 1992-12-24 1994-06-29 沈在中 The processing method of tea of throat care
CN103907707A (en) * 2014-03-14 2014-07-09 南京融点食品科技有限公司 Grosvenor-momordica-fruit lung-clearing tea and preparation method thereof
CN105381019A (en) * 2015-11-19 2016-03-09 南京优能生物科技有限公司 Effervescent tablet with internal-fire clearing function and preparation method thereof

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Application publication date: 20160622