CN105663987A

CN105663987A - Traditional Chinese medicine for treating puerperal mastitis

Info

Publication number: CN105663987A
Application number: CN201610133267.7A
Authority: CN
Inventors: 刘玉梅; 高爱梅
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-03-09
Filing date: 2016-03-09
Publication date: 2016-06-15

Abstract

The invention discloses a traditional Chinese medicine for treating puerperal mastitis, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10 parts of blackberrylily rhizome, 15 parts of cassia, 7 parts of ash bark, 5 parts of bighead atractylodes rhizome, 10 parts of frankincense, 12 parts of arisaema tuber, 7 parts of coptis root, 12 parts of chuanxiong rhizome, 10 parts of fructus toosendan, 5 parts of rhizoma alismatis, 6 parts of phellodendron bark, 8 parts of rhizoma anemarrhenae, 6 parts of officinal magnolia bark, 10 parts of pinellia tuber, 7 parts of panicled swallowwort root, 15 parts of kudzu root, 10 parts of rhizoma cimicifugae, 10 parts of plantain seed, 5 parts of roots of madder, 12 parts of herba kalimeridis, 7 parts of self-heal, 10 parts of herba scutellariae barbatae, 12 parts of achyranthes root, 10 parts of dodder, 10 parts of mistletoe, 5 parts of earthworms, 12 parts of macleaya cordata, 10 parts of carbonized sanguisorba root, 9 parts of moutan bark, 10 parts of motherwort, 7 parts of tuckahoe, 10 parts of red halloysite, 5 parts of fructus amomi, 6 parts of sophora flower and 10 parts of licorice. All traditional Chinese medicine raw materials are blended through syndrome differentiation, so that the traditional Chinese medicine disclosed by the invention has the effects of promoting blood circulation and removing blood stasis as well as eliminating stagnation and eliminating swelling, has obvious curative effects on patients suffering puerperal mastitis, and can be used for treating both symptoms and root causes.

Description

A kind of Chinese medicine treating puerperal mastitis

Technical field

The present invention relates to a kind of Chinese medicine treating puerperal mastitis, belong to the field of Chinese medicines.

Background technology

Owing to milk pipe is obstructed or milk gland does not all lead to, often there is acute mastitis in women breast-feeding their children, especially primipara. The mastitis initial stage, often there is high fever, long-pending milk has the symptom of lump, having a strong impact on the healthy of women breast-feeding their children, during hyperpyrexia, long-pending milk can not feed baby, affect the contact of neonatal breast feeding and mother and baby, mastitis persistent period length, gently then causes galactopoiesis amount to reduce, heavy then cause breast suppurative infection. Conventionally employed antibiotic carries out anti-inflammatory treatment, and severe one needs to carry out operating on drain, the body and mind of patient is caused serious impact, and it would furthermore be possible to therefore breast feeding can be terminated.

Summary of the invention

It is an object of the invention to provide a kind of Chinese medicine treating puerperal mastitis.

The adopted technical solution is that:

A kind of Chinese medicine treating puerperal mastitis, it is made up of the raw material of Chinese medicine of following weight parts proportioning: Rhizoma Belamcandae 3-15, Cortex Cinnamomi 7-20, Cortex Fraxini 5-15, Rhizoma Atractylodis Macrocephalae 2-12, Olibanum 3-15, Rhizoma Arisaematis 5-15, Rhizoma Coptidis 6-15, Rhizoma Chuanxiong 10-15, the sub-5-15 in river, Rhizoma Alismatis 3-18, Cortex Phellodendri 2-11, Rhizoma Anemarrhenae 6-15, Cortex Magnoliae Officinalis 2-17, Rhizoma Pinelliae 5-16, Radix Cynanchi Paniculati 2-10, Radix Puerariae 4-17, Rhizoma Cimicifugae 3-16, Semen Plantaginis 5-20, Radix Rubiae 3-12, Herba Kalimeridis grass 5-20, Spica Prunellae 6-12, Herba Scutellariae Barbatae 3-12, Radix Achyranthis Bidentatae 5-17, Semen Cuscutae 5-20, Herba Taxilli 5-17, Pheretima 2-15, Herba Macleayae Cordatae 10-15, charred Radix Sanguisorbae 8-15, Cortex Moutan 5-10, Herba Leonuri 5-12, Poria 5-20, Halloysitum Rubrum 5-15, Fructus Amomi 2-10, Flos Sophorae 3-12, Radix Glycyrrhizae 5-20.

Preferably, the weight of each raw material of Chinese medicine is: Rhizoma Belamcandae 10, Cortex Cinnamomi 15, Cortex Fraxini 7, the Rhizoma Atractylodis Macrocephalae 5, Olibanum 10, Rhizoma Arisaematis 12, Rhizoma Coptidis 7, Rhizoma Chuanxiong 12, river 10, Rhizoma Alismatis 5, Cortex Phellodendri 6, the Rhizoma Anemarrhenae 8, Cortex Magnoliae Officinalis 6, the Rhizoma Pinelliae 10, Radix Cynanchi Paniculati 7, Radix Puerariae 15, Rhizoma Cimicifugae 10, Semen Plantaginis 10, Radix Rubiae 5, Herba Kalimeridis grass 12, Spica Prunellae 7, Herba Scutellariae Barbatae 10, Radix Achyranthis Bidentatae 12, Semen Cuscutae 10, Herba Taxilli 10, Pheretima 5, Herba Macleayae Cordatae 12, charred Radix Sanguisorbae 10, Cortex Moutan 9, Herba Leonuri 10, Poria 7, Halloysitum Rubrum 10, Fructus Amomi 5, Flos Sophorae 6, Radix Glycyrrhizae 10.

Above-mentioned Chinese medicine can make the various dosage forms such as decoction, granule, pill, capsule according to a conventional method, and wherein the preparation method of decoction is as follows:

Weighing the mixing of above all medicines by above-mentioned weight, add 8 times of weight water, soak 2 hours, heating decocts 1.5 hours, filters to obtain decoction liquor one and residue; Residue adds 8 times of weight water again, and heating decocts 1 hour, filters to obtain decoction liquor two; Merge decoction liquor one and decoction liquor two, obtain decoction.

Pharmacology and the effect of the present invention are as follows:

The present invention chooses Rhizoma Belamcandae, Cortex Cinnamomi, Cortex Fraxini, the Rhizoma Atractylodis Macrocephalae, Olibanum, Rhizoma Arisaematis, Rhizoma Coptidis, Rhizoma Chuanxiong, river, Rhizoma Alismatis, Cortex Phellodendri, the Rhizoma Anemarrhenae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Cynanchi Paniculati, Radix Puerariae, Rhizoma Cimicifugae, Semen Plantaginis, Radix Rubiae, Herba Kalimeridis grass, Spica Prunellae, Herba Scutellariae Barbatae, Radix Achyranthis Bidentatae, Semen Cuscutae, Herba Taxilli, Pheretima, Herba Macleayae Cordatae, charred Radix Sanguisorbae, Cortex Moutan, Herba Leonuri, Poria, Halloysitum Rubrum, Fructus Amomi, Flos Sophorae, Radix Glycyrrhizae totally 35 taste raw material of Chinese medicine targetedly.

Wherein: Rhizoma Belamcandae, can heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm.

Cortex Cinnamomi, mends fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.

Cortex Fraxini, heat clearing and damp drying, liver heat removing and eyesight improving, astringent therapy dysentery relieving, leukorrhagia stopping.

The Rhizoma Atractylodis Macrocephalae, invigorating the spleen and benefiting QI, dampness diuretic;

Olibanum, regulating qi and activating blood;

Rhizoma Arisaematis, drying dampness to eliminate phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating;

Rhizoma Coptidis, heat clearing and damp drying, eliminating fire and detoxication;

Rhizoma Chuanxiong, blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression;

River, soothing liver-QI promoting the circulation of QI to relieve pain, dehumidifying heat, anthelmintic.

Rhizoma Alismatis, promoting diuresis to eliminate damp pathogen; Expel the heat-evil treating stranguria.

Cortex Phellodendri, bitter in the mouth, cold in nature. Heat-clearing and toxic substances removing, pathogenic fire purging dampness.

The Rhizoma Anemarrhenae, clearing away heat-fire, promotes the production of body fluid and moisturizes.

Cortex Magnoliae Officinalis, circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.

The Rhizoma Pinelliae, drying dampness to eliminate phlegm; Stopping nausea and vomiting by lowering the adverse flow of QI; Dissolving lump and resolving mass.

Radix Cynanchi Paniculati, removing dampness of dispeling the wind, antalgesic-antipruritic.

Radix Puerariae, yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is quenched the thirst.

Rhizoma Cimicifugae, delivers rash, heat-clearing and toxic substances removing, ascending up spleen-Qi and Yang.

Semen Plantaginis, relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm.

Radix Rubiae, qualcomm meridian, removes all dead blood.

Herba Kalimeridis grass, heat-clearing and toxic substances removing, pain relieving of dispeling cold.

Spica Prunellae, purging liver-fire, eliminating stagnation blood stasis dispelling.

Herba Scutellariae Barbatae, has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.

Radix Achyranthis Bidentatae, invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite descending; Inducing diuresis for treating stranguria syndrome.

Semen Cuscutae, the kidney invigorating and essence nourishing; Nourishing the liver to improve visual acuity; Gu tire stopping leak.

Herba Taxilli, invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.

Pheretima, clearing away heat and relieving the wind syndrome, suppressing the hyperactive liver blood pressure lowering, Lip river ruton numbness, clearing lung, relieving asthma, inducing diuresis for treating stranguria syndrome.

Herba Macleayae Cordatae, removing toxic substances of dispeling the wind, promoting the circulation of QI for relieving swelling, parasite killing.

Charred Radix Sanguisorbae, cooling blood for hemostasis, sore of detoxifying.

Cortex Moutan, clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.

Herba Leonuri, have invigorate blood circulation, the method stasis of blood, regulating menstruation, the water that disappears effect.

Poria, eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.

Halloysitum Rubrum, has astringing intestine to stop diarrhea, hemostasis, effect of promoting tissue regeneration and ulcer healing.

Fructus Amomi, regulating the flow of QI to ease the stomach, removing dampness and spleen, antiabortive.

Flos Sophorae, bitter and puckery flavor, cold in nature, there is effect of cooling blood for hemostasis.

Radix Glycyrrhizae, heat-clearing and toxic substances removing, expelling phlegm for arresting cough.

All medicines share above, play effect of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating altogether, and to puerperal mastitis, patient is evident in efficacy, can treating both the principal and secondary aspects of a disease.

Clinical data

1. physical data

Choose acute mastitis patient 100 example to our hospital, be primipara's postpartum women, age 20-35 year;Course of disease 2-4 days. It is randomly divided into matched group and each 50 examples for the treatment of group. Two groups of patient ages, final recognition, the course of disease, clinical manifestations etc. are no difference of science of statistics all.

2. diagnostic criteria

Clinical manifestation breast amasss milk, distending pain, heating, and local skin is red and swollen, block tuberosity lump, touches a tender spot substantially, and nipple is inaccessible, or with ipsilateral axillary lymphadenectasis.

3. Therapeutic Method

Matched group adopts existing routine medication, and treatment group adopts medicine of the present invention. Two groups all with 1 week for 1 course for the treatment of.

4. curative effect judging standard

Draft according to " Chinese medical disease Standardization of diagnosis and curative effect ".

Curing: General Symptoms disappears, lump dissipates, wound healing.

Take a turn for the better: General Symptoms disappears, and partial gall alleviates, or the open sore part not yet heals.

Do not heal: " biography capsule " or formation mammary fistula repeatedly.

5. therapeutic outcome

See table 1 below.

Table 1

Can be seen that from the therapeutic outcome shown in table 1, the cure rate of puerperal mastitis is 90% by Chinese medicine of the present invention, and total effective rate is 100%, and cure rate and total effective rate are obviously higher than matched group, evident in efficacy. And it is normal to adopt the patient overwhelming majority for the treatment of by Chinese herbs of the present invention to be attained by lochia.

Carrying out acute toxicity test for Chinese medicine of the present invention, related data is as follows:

(1) experimental animal: Kunming mouse (body weight 20 ± 2g), is provided by medicine inspecting institute of Qingdao City Experimental Animal Center;

(2) medicine: Chinese medicine of the present invention;

(3) test method: " requirement of study of tcm new drug technology " promulgating revision on November 12nd, 1999 according to National Drug Administration, carries out acute toxicity testing to the Chinese medicine of the present invention, because of by drug level and volumetric constraint, it is impossible to measure LD₅₀, therefore carry out maximum dosage-feeding test; Take Kunming mouse 30, male and female half and half, give Chinese medicinal capsule agent medicine 1g/ml of the present invention, every 0.8ml, the i.e. maximum gavage volume of mice, by observation post administration mice active state, diet, feces, breathing, body weight and death condition, Continuous Observation 14 days, records related data;

(4) result of the test: well-grown after each group mouse stomach administration, body weight increases, and behavior is normal, is showed no death and significant reaction, after sacrifice, each main organs of perusal phenomenon without exception.

Result proves, the Chinese medicine maximal dose oral application of preparation involved in the present invention, to animal without obvious damage, does not find body is produced toxic reaction, is a kind of safe and reliable Chinese medicine.

Detailed description of the invention

Embodiment 1

Each raw material of Chinese medicine is weighed by following weight:

Rhizoma Belamcandae 10, Cortex Cinnamomi 15, Cortex Fraxini 7, the Rhizoma Atractylodis Macrocephalae 5, Olibanum 10, Rhizoma Arisaematis 12, Rhizoma Coptidis 7, Rhizoma Chuanxiong 12, river 10, Rhizoma Alismatis 5, Cortex Phellodendri 6, the Rhizoma Anemarrhenae 8, Cortex Magnoliae Officinalis 6, the Rhizoma Pinelliae 10, Radix Cynanchi Paniculati 7, Radix Puerariae 15, Rhizoma Cimicifugae 10, Semen Plantaginis 10, Radix Rubiae 5, Herba Kalimeridis grass 12, Spica Prunellae 7, Herba Scutellariae Barbatae 10, Radix Achyranthis Bidentatae 12, Semen Cuscutae 10, Herba Taxilli 10, Pheretima 5, Herba Macleayae Cordatae 12, charred Radix Sanguisorbae 10, Cortex Moutan 9, Herba Leonuri 10, Poria 7, Halloysitum Rubrum 10, Fructus Amomi 5, Flos Sophorae 6, Radix Glycyrrhizae 10.

Preparation method is as follows:

Being mixed by above all medicines, add 8 times of weight water, soak 2 hours, heating decocts 1.5 hours, filters to obtain decoction liquor one and residue; Residue adds 8 times of weight water again, and heating decocts 1 hour, filters to obtain decoction liquor two; Merge decoction liquor one and decoction liquor two, obtain decoction.

Embodiment 2

Each raw material of Chinese medicine is weighed by following weight:

Rhizoma Belamcandae 3, Cortex Cinnamomi 20, Cortex Fraxini 5, the Rhizoma Atractylodis Macrocephalae 2, Olibanum 15, Rhizoma Arisaematis 5, Rhizoma Coptidis 15, Rhizoma Chuanxiong 10, river 5, Rhizoma Alismatis 18, Cortex Phellodendri 2, the Rhizoma Anemarrhenae 15, Cortex Magnoliae Officinalis 2, the Rhizoma Pinelliae 16, Radix Cynanchi Paniculati 2, Radix Puerariae 17, Rhizoma Cimicifugae 3, Semen Plantaginis 20, Radix Rubiae 3, Herba Kalimeridis grass 20, Spica Prunellae 6, Herba Scutellariae Barbatae 12, Radix Achyranthis Bidentatae 5, Semen Cuscutae 20, Herba Taxilli 5, Pheretima 15, Herba Macleayae Cordatae 10, charred Radix Sanguisorbae 8, Cortex Moutan 10, Herba Leonuri 5, Poria 5, Halloysitum Rubrum 15, Fructus Amomi 2, Flos Sophorae 12, Radix Glycyrrhizae 5.

Make capsule according to a conventional method.

Embodiment 3

Each raw material of Chinese medicine is weighed by following weight:

Rhizoma Belamcandae 15, Cortex Cinnamomi 7, Cortex Fraxini 15, the Rhizoma Atractylodis Macrocephalae 12, Olibanum 3, Rhizoma Arisaematis 15, Rhizoma Coptidis 6, Rhizoma Chuanxiong 15, river 15, Rhizoma Alismatis 3, Cortex Phellodendri 11, the Rhizoma Anemarrhenae 6, Cortex Magnoliae Officinalis 17, the Rhizoma Pinelliae 5, Radix Cynanchi Paniculati 10, Radix Puerariae 4, Rhizoma Cimicifugae 16, Semen Plantaginis 5, Radix Rubiae 12, Herba Kalimeridis grass 5, Spica Prunellae 12, Herba Scutellariae Barbatae 3, Radix Achyranthis Bidentatae 17, Semen Cuscutae 5, Herba Taxilli 17, Pheretima 2, Herba Macleayae Cordatae 15, charred Radix Sanguisorbae 15, Cortex Moutan 5, Herba Leonuri 12, Poria 20, Halloysitum Rubrum 5, Fructus Amomi 10, Flos Sophorae 3, Radix Glycyrrhizae 20.

Make pill according to a conventional method.

Claims

1. the Chinese medicine treating puerperal mastitis, it is characterized in that it is made up of the raw material of Chinese medicine of following weight parts proportioning: Rhizoma Belamcandae 3-15, Cortex Cinnamomi 7-20, Cortex Fraxini 5-15, Rhizoma Atractylodis Macrocephalae 2-12, Olibanum 3-15, Rhizoma Arisaematis 5-15, Rhizoma Coptidis 6-15, Rhizoma Chuanxiong 10-15, the sub-5-15 in river, Rhizoma Alismatis 3-18, Cortex Phellodendri 2-11, Rhizoma Anemarrhenae 6-15, Cortex Magnoliae Officinalis 2-17, Rhizoma Pinelliae 5-16, Radix Cynanchi Paniculati 2-10, Radix Puerariae 4-17, Rhizoma Cimicifugae 3-16, Semen Plantaginis 5-20, Radix Rubiae 3-12, Herba Kalimeridis grass 5-20, Spica Prunellae 6-12, Herba Scutellariae Barbatae 3-12, Radix Achyranthis Bidentatae 5-17, Semen Cuscutae 5-20, Herba Taxilli 5-17, Pheretima 2-15, Herba Macleayae Cordatae 10-15, charred Radix Sanguisorbae 8-15, Cortex Moutan 5-10, Herba Leonuri 5-12, Poria 5-20, Halloysitum Rubrum 5-15, Fructus Amomi 2-10, Flos Sophorae 3-12, Radix Glycyrrhizae 5-20.

2. a kind of Chinese medicine treating puerperal mastitis according to claim 1, it is characterized in that the weight of each raw material of Chinese medicine is: Rhizoma Belamcandae 10, Cortex Cinnamomi 15, Cortex Fraxini 7, the Rhizoma Atractylodis Macrocephalae 5, Olibanum 10, Rhizoma Arisaematis 12, Rhizoma Coptidis 7, Rhizoma Chuanxiong 12, river 10, Rhizoma Alismatis 5, Cortex Phellodendri 6, the Rhizoma Anemarrhenae 8, Cortex Magnoliae Officinalis 6, the Rhizoma Pinelliae 10, Radix Cynanchi Paniculati 7, Radix Puerariae 15, Rhizoma Cimicifugae 10, Semen Plantaginis 10, Radix Rubiae 5, Herba Kalimeridis grass 12, Spica Prunellae 7, Herba Scutellariae Barbatae 10, Radix Achyranthis Bidentatae 12, Semen Cuscutae 10, Herba Taxilli 10, Pheretima 5, Herba Macleayae Cordatae 12, charred Radix Sanguisorbae 10, Cortex Moutan 9, Herba Leonuri 10, Poria 7, Halloysitum Rubrum 10, Fructus Amomi 5, Flos Sophorae 6, Radix Glycyrrhizae 10.