CN105396034A

CN105396034A - Medicine for amebic dysentery

Info

Publication number: CN105396034A
Application number: CN201510862000.7A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-30
Filing date: 2015-11-30
Publication date: 2016-03-16

Abstract

The invention discloses a medicine for amebic dysentery. The medicine is prepared from the following traditional Chinese medicines through scientific and reasonable combination: malvastrum coromandelianum, aristolochia championii merr. et chun., pearly everlasting, patrinia heterophylla, herba portulacae, humifuse euphorbia herb, poria cocos, fructus psoraleae, liquorice root, fructus psoraleae, root of Chinese pulsatilla, dark plum, rhizoma alismatis, red jujube, scorched hawthorn fruit, liquorice root, fructus amomi, cortex cinnamomi, fructus aurantii, radix paeoniae rubra, radix puerariae, cortex phellodendri, radices lithospermi, saussurea costus, cortex ailanthic, verbena officinalis, hairyvein agrimony, rosa roxburghii tratt root, folium artemisiae argyi, platycodon grandiflorum, honeysuckle, fructus gardeniae, cortex dictamni, radix isatidis, radix ampelopsis, leaves of cinnamomum burm anii, rhizoma acori graminei, seed of Chinese dodder, hovenia acerba, rheum officinale, root of silverleaf cinquefoil, herba violae, indigo naturalis, cortex magnoliae, musk and the like. The medicine, on treating persistent dysentery and hemafecia, is good in curative effect and is not easy for reoccurrence after curing.

Description

A kind of medicine for amebic dysentery

Technical field

The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine for amebic dysentery.

Background technology

Amebic dysentery is the acute infectious intestinal disease caused by dysentery bacterium, because amoeba histolytica (Entamoeba histolytica) parasitizes colonic, causes amebic dysentery or amebic colitis.Amoebic causing a disease is that polypide and host interact, and is subject to the complex process of various factors, and the aggressivity of Entamoeba histolytica is mainly manifested in the dissolubility destruction to host tissue.The large trophozoite of Entamoeba histolytica, secondly invasion and attack intestinal wall causes amebiasis, and common position, at caecum, is rectum, sigmoid colon and vermiform appendix, transverse colon and descending colon rare, sometimes can involve all or part of ileum of large intestine.With abdominal pain diarrhea, tenesmus and mucopurulent bloody stool for main clinical manifestation, cause the General Symptomies such as heating, intestinal wall inflammation, epithelium necrosis, cause myxedema, hyperemia and glandular secretion hyperfunction, pseudomembrane and ulcer, thus produce the bowel symptoms such as stomachache, diarrhoea, bloody purulent stool.

Summary of the invention

In view of above-mentioned the deficiencies in the prior art, a kind of medicine for amebic dysentery that the object of the present invention is to provide.

For solving the problems of the technologies described above, technical solution of the present invention comprises:

For a medicine for amebic dysentery, it comprises following component according to weight portion:

Herba Malvastri Coromandeliani 3 parts-12 parts, three 5 parts-25 parts, bobbins, Shan bush clover 2 parts-14 parts, Radix Patriniae heterophyllae 3 parts-16 parts, Herba Portulacae 3 parts-12 parts, Herba Euphorbiae Humifusae 5 parts-15 parts, 20 parts-40 parts, Poria, Fructus Psoraleae 20 parts-40 parts, 10 parts-20 parts, Radix Glycyrrhizae, Fructus Evodiae 10 parts-30 parts, the Radix Pulsatillae 5 parts-15 parts, Fructus Mume 3 parts-12 parts, Rhizoma Alismatis 5 parts-25 parts, Fructus Jujubae 20 parts-40 parts, Fructus Crataegi (parched to brown) 5 parts-15 parts, Fructus Amomi 3 parts-12 parts, Cortex Cinnamomi 10 parts-20 parts, Fructus Aurantii 10 parts-30 parts, Radix Paeoniae Rubra 5 parts-15 parts, Radix Puerariae 3 parts-12 parts, Cortex Phellodendri 5 parts-15 parts, Radix Arnebiae (Radix Lithospermi) 10 parts-20 parts, Saussurea lappa Clarke 2 parts-14 parts, Cortex Ailanthi 3 parts-12 parts, Herba Verbenae 10 parts-30 parts, Herba Agrimoniae 20 parts-40 parts, Radix Rosae Normalis 3 parts-16 parts, Folium Artemisiae Argyi 10 parts-30 parts, Radix Platycodonis 3 parts-16 parts, Flos Lonicerae 3 parts-12 parts, Fructus Gardeniae 3 parts-12 parts, Cortex Dictamni 10 parts-30 parts, Radix Isatidis 5 parts-15 parts, Radix Ampelopsis 3 parts-16 parts, Folium Cinnamomi burmannii 5 parts-15 parts, Rhizoma Acori Graminei 10 parts-30 parts, Herba cuscutae 5 parts-25 parts, Semen Hoveniae (Fructus Hoveniae) 3 parts-12 parts, Radix Et Rhizoma Rhei 3 parts-12 parts, brocade line boomerang 3 parts-16 parts, Herba Violae 10 parts-30 parts, Indigo Naturalis 5 parts-15 parts, Cortex Magnoliae Officinalis 3 parts-12 parts and Herba Pogostemonis 5 parts-25 parts.

Described medicine, wherein, it comprises following component according to weight portion:

Herba Malvastri Coromandeliani 8 parts, three 15 parts, bobbins, Shan bush clover 8 parts, Radix Patriniae heterophyllae 10 parts, Herba Portulacae 7 parts, Herba Euphorbiae Humifusae 10 parts, 25 parts, Poria, Fructus Psoraleae 30 parts, 15 parts, Radix Glycyrrhizae, Fructus Evodiae 25 parts, the Radix Pulsatillae 10 parts, Fructus Mume 7 parts, Rhizoma Alismatis 15 parts, Fructus Jujubae 34 parts, Fructus Crataegi (parched to brown) 11 parts, Fructus Amomi 7 parts, Cortex Cinnamomi 15 parts, Fructus Aurantii 25 parts, Radix Paeoniae Rubra 10 parts, Radix Puerariae 7 parts, Cortex Phellodendri 10 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Saussurea lappa Clarke 8 parts, Cortex Ailanthi 6 parts, Herba Verbenae 20 parts, Herba Agrimoniae 29 parts, Radix Rosae Normalis 10 parts, Folium Artemisiae Argyi 25 parts, Radix Platycodonis 11 parts, Flos Lonicerae 7 parts, Fructus Gardeniae 6 parts, Cortex Dictamni 25 parts, Radix Isatidis 10 parts, Radix Ampelopsis 11 parts, Folium Cinnamomi burmannii 10 parts, Rhizoma Acori Graminei 22 parts, Herba cuscutae 16 parts, Semen Hoveniae (Fructus Hoveniae) 7 parts, Radix Et Rhizoma Rhei 6 parts, brocade line boomerang 12 parts, Herba Violae 20 parts, Indigo Naturalis 10 parts, Cortex Magnoliae Officinalis 7 parts and Herba Pogostemonis 19 parts.

The invention provides a kind of medicine for amebic dysentery, by Herba Malvastri Coromandeliani, three bobbins, Shan bush clover, Radix Patriniae heterophyllae, Herba Portulacae, Herba Euphorbiae Humifusae, Poria, Fructus Psoraleae, Radix Glycyrrhizae, Fructus Evodiae, the Radix Pulsatillae, Fructus Mume, Rhizoma Alismatis, Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Fructus Amomi, Cortex Cinnamomi, Fructus Aurantii, Radix Paeoniae Rubra, Radix Puerariae, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Saussurea lappa Clarke, Cortex Ailanthi, Herba Verbenae, Herba Agrimoniae, Radix Rosae Normalis, Folium Artemisiae Argyi, Radix Platycodonis, Flos Lonicerae, Fructus Gardeniae, Cortex Dictamni, Radix Isatidis, Radix Ampelopsis, Folium Cinnamomi burmannii, Rhizoma Acori Graminei, Herba cuscutae, Semen Hoveniae (Fructus Hoveniae), Radix Et Rhizoma Rhei, brocade line boomerang, Herba Violae, Indigo Naturalis, the kinds of traditional Chinese medicines such as Cortex Magnoliae Officinalis and Herba Pogostemonis carries out scientific and reasonable compatibility, be used for the treatment of persistence dysentery, to have blood in stool good effect, not easily recur after healing.Its basic pharmacology is as follows:

Herba Malvastri Coromandeliani, bitter, light, cool, clearing away heat-damp and promoting diuresis, removing toxic substances dissipating blood stasis;

Three bobbins are bitter; Cold, heat-clearing and toxic substances removing; Reducing swelling and alleviating pain;

Shan bush clover, micro-bitter, sweet, flat, heat-clearing and toxic substances removing, dispelling wind and removing obstruction in the collateral, anthelmintic;

Radix Patriniae heterophyllae, bitter, micro-acid, puckery, cool, heat clearing and damp drying, hemostasis, leukorrhagia stopping, preventing the attack (or recurrence) of malaria;

Herba Portulacae, heat-clearing and toxic substances removing, loose blood detumescence.Control hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, trace scrofula;

Herba Euphorbiae Humifusae, acrid in the mouth, property is put down, heat-clearing and toxic substances removing, cooling blood for hemostasis, dampness removing jaundice eliminating;

Poria, sweet in the mouth, light, property is put down, promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming;

Fructus Psoraleae, bitter, pungent, warm; Kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition;

Radix Glycyrrhizae, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen;

Fructus Evodiae, warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, headache due to JUE YIN disorder, and the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention;

The Radix Pulsatillae, has effect of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites;

Fructus Mume, sour in the mouth, puckery, property is put down, and astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris;

Rhizoma Alismatis, sweet, cold, diuretic, eliminating dampness by diuresis, expels the heat-evil;

Fructus Jujubae, nourishing YIN and invigorating YANG, the effect of enriching blood;

Fructus Crataegi (parched to brown), sour, sweet, tepor; Promoting digestion and invigorating the stomach, circulation of qi promoting is fallen apart;

Fructus Amomi, pungent, temperature; During circulation of qi promoting is adjusted, stomach function regulating, is amusing;

Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation;

Fructus Aurantii, dispelling the stagnated QI, row expectorant, removing food stagnancy;

Radix Paeoniae Rubra, bitter in the mouth, cold nature, clearing away heat and cooling blood, eliminating stasis to stop pain;

Radix Puerariae, sweet in the mouth, pungent, cool in nature; Expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal;

Cortex Phellodendri, bitter in the mouth, cold in nature; Have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment;

Radix Arnebiae (Radix Lithospermi), bitter, cold, removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances;

Saussurea lappa Clarke, acrid in the mouth, hardship, promoting the circulation of QI to relieve pain, regulate the flow of vital energy soothing the liver, spleen invigorating disappears stagnant;

Cortex Ailanthi, bitter in the mouth, puckery, cold in nature, heat clearing and damp drying, astringent therapy leukorrhagia stopping, antidiarrheal, hemostasis;

Herba Verbenae, bitter, cool, heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema;

Herba Agrimoniae, bitter, cool, anticancer, the cooling blood for hemostasis of relieving internal heat, detumescent of healing the wounds;

Radix Rosae Normalis, sweet acid, puckery, stomach invigorating, helps digestion, antidiarrheal, arresting seminal emission;

Folium Artemisiae Argyi, pungent, bitter, temperature, warming the meridian for stopping bleeding, dispersing cold for relieving pain; External removing dampness to relieve itching;

Radix Platycodonis, lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus;

Flos Lonicerae, dispelling wind-heat, removing summer-heat blood poison;

Fructus Gardeniae, heat clearing away, pathogenic fire purging, removing heat from blood;

Cortex Dictamni is bitter; Salty; Cold; Heat clearing and damp drying; Dispelling wind for relieving itching; Removing toxic substances;

Radix Isatidis, cold in nature, taste is micro-sweet rear bitterness first, has effect of heat-clearing and toxic substances removing, sore-throat relieving

Radix Ampelopsis, heat-clearing and toxic substances removing; Removing obstruction for relieving pain; Promoting tissue regeneration and ulcer healing;

Folium Cinnamomi burmannii, pungent, temperature; Wind-damp dispelling, antidiarrheal;

Rhizoma Acori Graminei, removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae;

Herba cuscutae, bitter in the mouth, sweet, property is put down; For dysentery, jaundice, spit blood, epistaxis, has blood in stool, metrorrhagia, stranguria with turbid discharge, leukorrhagia, loose stool;

Semen Hoveniae (Fructus Hoveniae), clearing away heat and promoting diuresis, cough-relieving relieving restlessness, alcoholic intoxication;

Radix Et Rhizoma Rhei, attacks the effects such as stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances;

Brocade line boomerang is pungent, bitter, flat; Heat-clearing and toxic substances removing.Cure mainly acute appendicitis, wind heat celostomia, dysentery;

Herba Violae, bitter in the mouth, micro-pungent, there is heat-clearing and toxic substances removing, effect of removing heat from blood detumescence;

Indigo Naturalis, salty, cold, heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, pathogenic fire purging is calmed the frightened;

Cortex Magnoliae Officinalis, bitter; Pungent; Warm in nature, circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma;

Herba Pogostemonis, pungent, tepor; Eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver expelling summer-heat.

Clinical data:

For showing the therapeutic effect of medicine of the present invention, the present invention carries out the clinical research of system through 100 routine amebic dysenterys, and 100 routine cases all derive from development zone in Qingdao hospital.

Treatment group: choose 50 examples by random method, take Drug therapy of the present invention 2 weeks.

Matched group: choose 50 examples by random method, takes Furazolidone tablet treatment 2 weeks.

Two groups in the state of an illness, sex, age, the course of disease etc. through statistical procedures no significant difference.

Instructions of taking: treatment group: the decoction 220 milliliters sooner or later respectively once taking medicine of the present invention every day, treats 2 weeks.Matched group: give Furazolidone tablet, one time 1, every day 3 times, buccal after the meal, treats 2 weeks.

Observation index and method

With reference to the standard of " new Chinese medicine guideline of clinical investigations ".

Treatment group, cures 40 examples, effective 10 examples, invalid 0 example, total effective rate 100%.Matched group, cures 30 examples, effective 10 examples, invalid 10 examples, total effective rate 80%.Between two groups, difference has very significant, and treatment group is obviously better than matched group.

Detailed description of the invention

The invention provides a kind of medicine for amebic dysentery, for making object of the present invention, technical scheme and effect clearly, clearly, the present invention is described in more detail below.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.

Embodiment 1

Herba Malvastri Coromandeliani 12 parts, three 25 parts, bobbins, Shan bush clover 14 parts, Radix Patriniae heterophyllae 16 parts, Herba Portulacae 12 parts, Herba Euphorbiae Humifusae 15 parts, 40 parts, Poria, Fructus Psoraleae 40 parts, 20 parts, Radix Glycyrrhizae, Fructus Evodiae 30 parts, the Radix Pulsatillae 15 parts, Fructus Mume 12 parts, Rhizoma Alismatis 25 parts, Fructus Jujubae 40 parts, Fructus Crataegi (parched to brown) 15 parts, Fructus Amomi 12 parts, Cortex Cinnamomi 20 parts, Fructus Aurantii 30 parts, Radix Paeoniae Rubra 15 parts, Radix Puerariae 12 parts, Cortex Phellodendri 15 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Saussurea lappa Clarke 14 parts, Cortex Ailanthi 12 parts, Herba Verbenae 30 parts, Herba Agrimoniae 40 parts, Radix Rosae Normalis 16 parts, Folium Artemisiae Argyi 30 parts, Radix Platycodonis 16 parts, Flos Lonicerae 12 parts, Fructus Gardeniae 12 parts, Cortex Dictamni 30 parts, Radix Isatidis 15 parts, Radix Ampelopsis 16 parts, Folium Cinnamomi burmannii 15 parts, Rhizoma Acori Graminei 30 parts, Herba cuscutae 25 parts, Semen Hoveniae (Fructus Hoveniae) 12 parts, Radix Et Rhizoma Rhei 12 parts, brocade line boomerang 16 parts, Herba Violae 130 parts, Indigo Naturalis 15 parts, Cortex Magnoliae Officinalis 12 parts and Herba Pogostemonis 25 parts.

The preparation method of said medicine is as follows:

(1) according to above-mentioned weight by Herba Malvastri Coromandeliani, three bobbins, Shan bush clover, Radix Patriniae heterophyllae, Herba Portulacae, Herba Euphorbiae Humifusae, Poria, Fructus Psoraleae, Radix Glycyrrhizae, Fructus Evodiae, the Radix Pulsatillae, Fructus Mume, Rhizoma Alismatis, Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Fructus Amomi, Cortex Cinnamomi, Fructus Aurantii, Radix Paeoniae Rubra, Radix Puerariae, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Saussurea lappa Clarke, Cortex Ailanthi, Herba Verbenae, Herba Agrimoniae, Radix Rosae Normalis, Folium Artemisiae Argyi, Radix Platycodonis, Flos Lonicerae, Fructus Gardeniae, Cortex Dictamni, Radix Isatidis, Radix Ampelopsis, Folium Cinnamomi burmannii, Rhizoma Acori Graminei, Herba cuscutae, Semen Hoveniae (Fructus Hoveniae), Radix Et Rhizoma Rhei, brocade line boomerang, Herba Violae, Indigo Naturalis, water caltrop, Cortex Magnoliae Officinalis and Herba Pogostemonis, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:5, soak 20 minutes in water.

(2) mixture in described step (1) and soak by water, after 50 minutes, are filtered and obtain the first filtrate and filtering residue.

(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:7, then decoct 90 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.

Toxicity test: rat 60, Quan Xiong, 150 ~ 200g, be divided into 6 groups at random, often organizes 10.That is:

(1) blank group: gavage gives normal saline 10ml/kg;

(2) model group: gavage gives 10%CCl ₄10ml/kg;

(3) positive controls: gavage gives silibinin 5mg/kg;

(4) medicine low dose group of the present invention: gavage gives Chinese medicine composition 1g/kg of the present invention;

(5)) dosage group: 2g/kg in medicine of the present invention;

(6)) drug bolus group of the present invention: 4g/kg.Except blank group, respectively organize equal gavage give 10% ethanol, continuous 12 weeks, after 2 weeks on-tests, single gives 50%CCl ₄, give 1ml25%CCl every 2 times when giving thereafter ethanol ₄.Successive administration 4 weeks

Result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to rat all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Embodiment 2

The preparation method of said medicine is as follows:

Embodiment 3

Herba Malvastri Coromandeliani 3 parts, three 5 parts, bobbins, Shan bush clover 2 parts, Radix Patriniae heterophyllae 3 parts, Herba Portulacae 3 parts, Herba Euphorbiae Humifusae 5 parts, 20 parts, Poria, Fructus Psoraleae 20 parts, 10 parts, Radix Glycyrrhizae, Fructus Evodiae 10 parts, the Radix Pulsatillae 5 parts, Fructus Mume 3 parts, Rhizoma Alismatis 5 parts, Fructus Jujubae 20 parts, Fructus Crataegi (parched to brown) 5 parts, Fructus Amomi 3 parts, Cortex Cinnamomi 10 parts, Fructus Aurantii 10 parts, Radix Paeoniae Rubra 5 parts, Radix Puerariae 3 parts, Cortex Phellodendri 5 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Saussurea lappa Clarke 2 parts, Cortex Ailanthi 3 parts, Herba Verbenae 10 parts, Herba Agrimoniae 20 parts, Radix Rosae Normalis 3 parts, Folium Artemisiae Argyi 10 parts, Radix Platycodonis 3 parts, Flos Lonicerae 3 parts, Fructus Gardeniae 3 parts, Cortex Dictamni 10 parts, Radix Isatidis 5 parts, Radix Ampelopsis 3 parts, Folium Cinnamomi burmannii 5 parts, Rhizoma Acori Graminei 10 parts, Herba cuscutae 5 parts, Semen Hoveniae (Fructus Hoveniae) 3 parts, Radix Et Rhizoma Rhei 3 parts, brocade line boomerang 3 parts, Herba Violae 10 parts, Indigo Naturalis 5 parts, Cortex Magnoliae Officinalis 3 parts and Herba Pogostemonis 5 parts.

The preparation method of said medicine is as follows:

Certainly; more than illustrate and be only preferred embodiment of the present invention; the present invention is not limited to enumerate above-described embodiment; should be noted that; any those of ordinary skill in the art are under the instruction of this description; made all equivalently to substitute, obvious variant, within the essential scope all dropping on this description, protection of the present invention ought to be subject to.

Claims

1., for a medicine for amebic dysentery, it comprises following component according to weight portion:

2. medicine according to claim 1, is characterized in that, it comprises following component according to weight portion:

Herba Malvastri Coromandeliani 8 parts, three 15 parts, bobbins, Shan bush clover 8 parts, Radix Patriniae heterophyllae 10 parts, Herba Portulacae 7 parts, Herba Euphorbiae Humifusae 10 parts, 25 parts, Poria, Fructus Psoraleae 30 parts, Fructus Evodiae 25 parts, the Radix Pulsatillae 10 parts, Fructus Mume 7 parts, Rhizoma Alismatis 15 parts, Fructus Jujubae 34 parts, Fructus Crataegi (parched to brown) 11 parts, 11 parts, Radix Glycyrrhizae, Fructus Amomi 7 parts, Cortex Cinnamomi 15 parts, Fructus Aurantii 25 parts, Radix Paeoniae Rubra 10 parts, Radix Puerariae 7 parts, Cortex Phellodendri 10 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Saussurea lappa Clarke 8 parts, Cortex Ailanthi 6 parts, Herba Verbenae 20 parts, Herba Agrimoniae 29 parts, Radix Rosae Normalis 10 parts, Folium Artemisiae Argyi 25 parts, Radix Platycodonis 11 parts, Flos Lonicerae 7 parts, Fructus Gardeniae 6 parts, Cortex Dictamni 25 parts, Radix Isatidis 10 parts, Radix Ampelopsis 11 parts, Folium Cinnamomi burmannii 10 parts, Rhizoma Acori Graminei 22 parts, Herba cuscutae 16 parts, Semen Hoveniae (Fructus Hoveniae) 7 parts, Radix Et Rhizoma Rhei 6 parts, brocade line boomerang 12 parts, Herba Violae 20 parts, Indigo Naturalis 10 parts, Cortex Magnoliae Officinalis 7 parts and Herba Pogostemonis 19 parts.