CN105250938A - Drug for damp-heat type cirrhotic ascites - Google Patents

Abstract

The invention discloses a drug for damp-heat type cirrhotic ascites. Many kinds of traditional Chinese medicine such as herbs of sievers wormwood, humata tyermanni, henbit deadnettle, licorice roots, radix knoxiae, achyranthes aspera, largehead atractylodes rhizome, black soybeans, mole crickets, herba selaginellae doederleinii, fructus forsythiae, radix scutellariae, verbena officinalis, herbs of ghostplant wormwood, common bletilla pseudobulb, artocarpus hypargyraus Hance., peach seeds, cortex magnoliae officinalis, indigowoad roots, unibract fritillary bulbs, milkvetch roots, pericarpium citri reticulatae, turmeric, obstinate pudendal sore, radix gentianae macrophyllae, ilex asprella, panax notoginseng, fructus ligustri lucidi, herba lysimachiae, common burreed rhizome, buddleja asiatica, common selfheal fruit-spike, radix bupleuri, gentiana scabra bunge, herba artemisiae scopariae, plantain seeds, kansui roots, dried rhizome of rehmannia and radix puerariae are subjected to scientific and reasonable compatibility. The effects of clearing the liver, benefiting bile, expelling wind, promoting diuresis, removing toxicity, discharging fire, soothing the liver, strengthening the spleen, promoting blood circulation to remove blood stasis, moistening the spleen, removing dampness, regulating Qi, excreting water, dispelling stasis, activating collaterals, invigorating circulation of water, nourishing the liver and the kidney, nourishing Yin and alleviating water retention are achieved, and the liver function is facilitated to return to normal.

Description

A kind of medicine for damp-heat type cirrhotic ascites

Technical field

The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine for damp-heat type cirrhotic ascites.

Background technology

Liver cirrhosis is clinical common chronic progressive external hepatopathy, the diffusivity hepatic injury that long-term or repeated action is formed by one or more causes of disease.In China, great majority are posthepatitic cirrhosis, and small part is alcoholic cirrhosis and Cirrhosis In Schistosomiasis.Histopathology there are hepatic necrosis, the regeneration of remaining liver cell nodules, connective tissue proliferation and fiber widely every formation, cause lobules of liver structural deterioration and pseudolobuli formation, liver is out of shape gradually, hardening and develop into liver cirrhosis.In early days because liver compensation more by force can non-evident sympton, stage with liver function injury and portal hypertension for main manifestations, and have multisystem to get involved, often there is the complication such as upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection, hypersplenism, ascites, canceration late period.Cirrhotic ascites is commonly called as hepatic ascites, and therefore the modal cause of disease of ascites is liver cirrhosis.During liver cirrhosis, due to hepatocellular degeneration, necrosis, proliferation of fibrous tissue, cause vascular bed pressurized in liver, distortion, distortion, narrow, block blood vessel, make sinus hepaticus congestion, blood flow reduces greatly, and input quantity is obviously greater than output, and a caval vein pressure is raised.Meanwhile, blood capillary vein pressure also raises, and in the course of time, the obstruction of blood return such as gastrointestinal tract, mesentery, peritoneum, vascular permeability raises, and the plasma fraction in blood leaks outside, and defines ascites.

Summary of the invention

In view of above-mentioned the deficiencies in the prior art, the object of the present invention is to provide a kind of medicine for damp-heat type cirrhotic ascites.

For solving the problems of the technologies described above, technical solution of the present invention comprises:

For a medicine for damp-heat type cirrhotic ascites, it comprises following component according to weight portion:

Herba Artemisiae Sieversianae 3 parts-16 parts, Parathelypteris glanduligera (Kunze) Ching 5 parts-17 parts, Herba Lamii Amplexicaulis 3 parts-16 parts, 5 parts-10 parts, Radix Glycyrrhizae, Radix Knoxiae 1 part-7 parts, Radix Achyranthis 5 parts-30 parts, the Rhizoma Atractylodis Macrocephalae 5 parts-30 parts, 5 parts-30 parts, Semen sojae atricolor, Gryllotalpa 3 parts-16 parts, Herba Selaginellae Doederleinii 5 parts-20 parts, Fructus Forsythiae 5 parts-20 parts, Radix Scutellariae 5 parts-20 parts, Herba Verbenae 15 parts-20 parts, Herba artemisiae lactiflorae 5 parts-20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts-20 parts, Bai Guimu root 5 parts-17 parts, 5 parts-17 parts, Semen Persicae, Cortex Magnoliae Officinalis 3 parts-12 parts, Radix Isatidis 5 parts-17 parts, Bulbus Fritillariae Cirrhosae 5 parts-10 parts, the Radix Astragali 5 parts-10 parts, Pericarpium Citri Reticulatae 5 parts-17 parts, 3 parts-16 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 5 parts-10 parts, Radix Gentianae Macrophyllae 1 part-7 parts, Flos Ilicis Asprellae 5 parts-10 parts, Radix Notoginseng 3 parts-16 parts, Fructus Ligustri Lucidi 15 parts-20 parts, Herba Lysimachiae 3 parts-16 parts, Rhizoma Sparganii 15 parts-20 parts, Buddleja asiatica 1 part-5 parts, Spica Prunellae 5 parts-17 parts, Radix Bupleuri 5 parts-20 parts, Radix Gentianae 5 parts-10 parts, Herba Artemisiae Scopariae 5 parts-10 parts, Semen Plantaginis 2 parts-10 parts, Radix Kansui 10 parts-20 parts, 10 parts-20 parts, the Radix Rehmanniae and Radix Puerariae 5 parts-10 parts.

Described medicine, wherein, it comprises following component according to weight portion:

Herba Artemisiae Sieversianae 10 parts, Parathelypteris glanduligera (Kunze) Ching 11 parts, Herba Lamii Amplexicaulis 12 parts, 8 parts, Radix Glycyrrhizae, Radix Knoxiae 4 parts, Radix Achyranthis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 21 parts, Semen sojae atricolor, Gryllotalpa 12 parts, Herba Selaginellae Doederleinii 15 parts, Fructus Forsythiae 13 parts, Radix Scutellariae 14 parts, Herba Verbenae 16 parts, Herba artemisiae lactiflorae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, Bai Guimu root 12 parts, 13 parts, Semen Persicae, Cortex Magnoliae Officinalis 8 parts, Radix Isatidis 11 parts, Bulbus Fritillariae Cirrhosae 8 parts, the Radix Astragali 7 parts, Pericarpium Citri Reticulatae 12 parts, 12 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 6 parts, Radix Gentianae Macrophyllae 5 parts, Flos Ilicis Asprellae 7 parts, Radix Notoginseng 13 parts, Fructus Ligustri Lucidi 17 parts, Herba Lysimachiae 10 parts, Rhizoma Sparganii 17 parts, Buddleja asiatica 3 parts, Spica Prunellae 12 parts, Radix Bupleuri 13 parts, Radix Gentianae 6 parts, Herba Artemisiae Scopariae 7 parts, Semen Plantaginis 6 parts, Radix Kansui 15 parts, 15 parts, the Radix Rehmanniae and Radix Puerariae 7 parts.

A kind of medicine for damp-heat type cirrhotic ascites provided by the invention, by Herba Artemisiae Sieversianae, Parathelypteris glanduligera (Kunze) Ching, Herba Lamii Amplexicaulis, Radix Glycyrrhizae, Radix Knoxiae, Radix Achyranthis, the Rhizoma Atractylodis Macrocephalae, Semen sojae atricolor, Gryllotalpa, Herba Selaginellae Doederleinii, Fructus Forsythiae, Radix Scutellariae, Herba Verbenae, Herba artemisiae lactiflorae, Pseudobulbus Bletillae (Rhizoma Bletillae), Bai Guimu root, Semen Persicae, Cortex Magnoliae Officinalis, Radix Isatidis, Bulbus Fritillariae Cirrhosae, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Curcumae Longae, obstinate pudendal sore, Radix Gentianae Macrophyllae, Flos Ilicis Asprellae, Radix Notoginseng, Fructus Ligustri Lucidi, Herba Lysimachiae, Rhizoma Sparganii, Buddleja asiatica, Spica Prunellae, Radix Bupleuri, Radix Gentianae, Herba Artemisiae Scopariae, Semen Plantaginis, Radix Kansui, the kinds of traditional Chinese medicines such as the Radix Rehmanniae and Radix Puerariae carries out scientific and reasonable compatibility, there is liver heat removing function of gallbladder promoting, expelling wind and removing dampness, removing toxic substances pathogenic fire purging effect, soothing liver and strengthening spleen, blood circulation promoting and blood stasis dispelling, and to regulate the flow of vital energy row water eliminating blood stasis and smoothing collaterals from profit spleen dampness removing of invigorating blood circulation, invigorating blood circulation water, nourishing the liver and kidney, yin nourishing diuretic, promote that liver function recovery is normal, clinical in damp-heat type hepatitis A, hepatitis B and liver cirrhosis, hepatic ascites is evident in efficacy.Its pharmacology is specific as follows:

Herba Artemisiae Sieversianae, has clearing away heat-damp and promoting diuresis; Effect of cooling blood for hemostasis,

Parathelypteris glanduligera (Kunze) Ching, micro-hardship, sweet, flat, expelling wind and removing dampness, hemostasis, diuresis;

Herba Lamii Amplexicaulis, pungent, bitter, flat, clearing away heat-damp and promoting diuresis, promoting blood circulation by removing wind, subduing swelling and detoxicating;

Radix Glycyrrhizae, feeble QI, taste is sweet, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen;

Radix Knoxiae, bitter in the mouth, cold in nature, removing fluid-retention by purgation, dispersing swelling and dissipating binds;

Radix Achyranthis, heat-clearing and toxic substances removing, diuresis effect;

The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis;

Semen sojae atricolor, sweet in the mouth, cold nature, property is put down, energy the kidney invigorating tonifying YIN, and invigorating spleen to remove dampness, except thermal detoxification;

Gryllotalpa, nature and flavor are salty, cold, diuretic relieving constipation;

Herba Selaginellae Doederleinii, sweet in the mouth, micro-hardship, puckery, cool in nature, heat-clearing and toxic substances removing, anticancer, hemostasis;

Fructus Forsythiae, bitter in the mouth, flat, heat clearing away, removing toxic substances, eliminating stagnation, detumescence;

Radix Scutellariae, bitter, cold, removing the relative excess fire, except damp and hot, hemostasis;

Herba Verbenae, bitter, cool, heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema;

Herba artemisiae lactiflorae, promoting blood circulation to remove blood stasis; Regulating QI to expel dampness;

Pseudobulbus Bletillae (Rhizoma Bletillae), bitter, sweet, puckery, be slightly cold, astringing to arrest bleeding, detumescence and promoting granulation;

Bai Guimu root, sweet; Light; Warm in nature, rheumatic arthralgia;

Semen Persicae, bitter, sweet, flat, blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation;

Cortex Magnoliae Officinalis, bitter; Pungent; Warm in nature, circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma;

Radix Isatidis, cold in nature, taste is micro-sweet rear bitterness first, has effect of heat-clearing and toxic substances removing, preventing cold, sore-throat relieving;

Bulbus Fritillariae Cirrhosae, bitter in the mouth, sweet, cold nature, removing heat-phlegm, nourishing the lung to arrest cough, mass dissipating and swelling eliminating;

The Radix Astragali, nature and flavor: sweet, tepor, enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering;

Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature, regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm;

Rhizoma Curcumae Longae, arduous, temperature; Removing blood stasis, circulation of qi promoting, stimulates the menstrual flow, pain relieving;

Obstinate pudendal sore, acrid in the mouth, property is put down, expelling wind and removing dampness, strong waist knee joint, reducing swelling and alleviating pain;

Radix Gentianae Macrophyllae, pungent, bitter, flat, wind-damp dispelling, clearing away damp-heat, stopping numbness pain;

Flos Ilicis Asprellae, bitter, sweet, cool, heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst;

Radix Notoginseng, sweet, micro-hardship, temperature, dissipating blood stasis stops blooding, subduing swelling and relieving pain;

Fructus Ligustri Lucidi, sweet, bitter, cold, liver and kidney tonifying, improving eyesight, clearind deficient heat;

Herba Lysimachiae, sweet in the mouth, micro-hardship, cool in nature, relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, eliminating damp-heat, Sha Lin, urine is puckery has a pain;

Rhizoma Sparganii, pungent, bitter, flat, removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving;

Buddleja asiatica, pungent, bitter, temperature, expelling wind and removing dampness, promoting flow of QI and blood;

Spica Prunellae is pungent, bitter, cold; Clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating;

Radix Bupleuri, acrid in the mouth, hardship, cold nature, reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, preventing the attack (or recurrence) of malaria of bringing down a fever;

Radix Gentianae, bitter in the mouth, cold in nature, heat clearing and damp drying, eliminating pathogen in the liver is calmed the frightened;

Herba Artemisiae Scopariae, bitter, pungent, be slightly cold, Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis; Jaundice eliminating;

Semen Plantaginis, sweet, cold, diuretic, heat clearing away, improving eyesight, eliminates the phlegm;

Radix Kansui, bitter in the mouth; Cold in nature; Poisonous, removing water retention by purgation by swollen, dispersing swelling and dissipating binds;

The Radix Rehmanniae, sweet, cold, clearing away heat and cooling blood, tonifying YIN promote the production of body fluid;

Radix Puerariae, sweet in the mouth, pungent, cool in nature, expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.

Clinical data:

For showing the therapeutic effect of medicine of the present invention, the present invention carries out the clinical research of system through 100 routine liver cirrhosis, and 100 routine cases all derive from development zone in Qingdao hospital.

Treatment group: choose 50 examples by random method, take Drug therapy of the present invention 4 weeks.

Matched group: choose 50 examples by random method, take lamivudine therapy 4 weeks.

Two groups in the state of an illness, sex, age, the course of disease etc. through statistical procedures no significant difference.

Instructions of taking: treatment group: the decoction 210 milliliters sooner or later respectively once taking medicine of the present invention every day, treats 4 weeks.Matched group: give lamivudine, one time 1, every day 1 time, buccal after the meal, treats 4 weeks.

Observation index and method

With reference to the standard of " new Chinese medicine guideline of clinical investigations ".

Treatment group, cures 40 examples, effective 10 examples, invalid 0 example, total effective rate 100%.Matched group, cures 30 examples, effective 10 examples, invalid 10 examples, total effective rate 80%.Between two groups, difference has very significant, and treatment group is obviously better than matched group.

Detailed description of the invention

The invention provides a kind of medicine for damp-heat type cirrhotic ascites, for making object of the present invention, technical scheme and effect clearly, clearly, the present invention is described in more detail below.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.

Embodiment 1

For a medicine for damp-heat type cirrhotic ascites, it comprises following component according to weight portion:

Herba Artemisiae Sieversianae 3 parts, Parathelypteris glanduligera (Kunze) Ching 5 parts, Herba Lamii Amplexicaulis 3 parts, 5 parts, Radix Glycyrrhizae, Radix Knoxiae 1 part, Radix Achyranthis 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, 5 parts, Semen sojae atricolor, Gryllotalpa 3 parts, Herba Selaginellae Doederleinii 5 parts, Fructus Forsythiae 5 parts, Radix Scutellariae 5 parts, Herba Verbenae 15 parts, Herba artemisiae lactiflorae 5 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Bai Guimu root 5 parts, 5 parts, Semen Persicae, Cortex Magnoliae Officinalis 3 parts, Radix Isatidis 5 parts, Bulbus Fritillariae Cirrhosae 5 parts, the Radix Astragali 5 parts, Pericarpium Citri Reticulatae 5 parts, 3 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 5 parts, Radix Gentianae Macrophyllae 3 parts, Flos Ilicis Asprellae 5 parts, Radix Notoginseng 3 parts, Fructus Ligustri Lucidi 15 parts, Herba Lysimachiae 3 parts, Rhizoma Sparganii 15 parts, Buddleja asiatica 3 parts, Spica Prunellae 5 parts, Radix Bupleuri 5 parts, Radix Gentianae 5 parts, Herba Artemisiae Scopariae 5 parts, Semen Plantaginis 2 parts, Radix Kansui 10 parts, 10 parts, the Radix Rehmanniae and Radix Puerariae 5 parts.

The preparation method of said medicine is as follows:

(1) according to above-mentioned weight by Herba Artemisiae Sieversianae, Parathelypteris glanduligera (Kunze) Ching, Herba Lamii Amplexicaulis, Radix Glycyrrhizae, Radix Knoxiae, Radix Achyranthis, the Rhizoma Atractylodis Macrocephalae, Semen sojae atricolor, Gryllotalpa, Herba Selaginellae Doederleinii, Fructus Forsythiae, Radix Scutellariae, Herba Verbenae, Herba artemisiae lactiflorae, Pseudobulbus Bletillae (Rhizoma Bletillae), Bai Guimu root, Semen Persicae, Cortex Magnoliae Officinalis, Radix Isatidis, Bulbus Fritillariae Cirrhosae, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Curcumae Longae, obstinate pudendal sore, Radix Gentianae Macrophyllae, Flos Ilicis Asprellae, Radix Notoginseng, Fructus Ligustri Lucidi, Herba Lysimachiae, Rhizoma Sparganii, Buddleja asiatica, Spica Prunellae, Radix Bupleuri, Radix Gentianae, Herba Artemisiae Scopariae, Semen Plantaginis, Radix Kansui, the Radix Rehmanniae and Radix Puerariae, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:6, soak 30 minutes in water.

(2) mixture in described step (1) and soak by water, after 60 minutes, are filtered and obtain the first filtrate and filtering residue.

(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:4, then decoct 80 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.

Toxicity test: rat 60, Quan Xiong, 150 ~ 200g, be divided into 6 groups at random, often organizes 10.That is:

(1) blank group: gavage gives normal saline 10ml/kg;

(2) model group: gavage gives 10%CCl ₄10ml/kg;

(3) positive controls: gavage gives silibinin 5mg/kg;

(4) medicine low dose group of the present invention: gavage gives Chinese medicine composition 1g/kg of the present invention;

(5)) dosage group: 2g/kg in medicine of the present invention;

(6)) drug bolus group of the present invention: 4g/kg.Except blank group, respectively organize equal gavage give 10% ethanol, continuous 12 weeks, after 2 weeks on-tests, single gives 50%CCl ₄, give 1ml25%CCl every 2 times when giving thereafter ethanol ₄.Successive administration 4 weeks

Result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to rat all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Embodiment 2

For a medicine for damp-heat type cirrhotic ascites, it comprises following component according to weight portion

Herba Artemisiae Sieversianae 10 parts, Parathelypteris glanduligera (Kunze) Ching 11 parts, Herba Lamii Amplexicaulis 12 parts, 8 parts, Radix Glycyrrhizae, Radix Knoxiae 4 parts, Radix Achyranthis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 21 parts, Semen sojae atricolor, Gryllotalpa 12 parts, Herba Selaginellae Doederleinii 15 parts, Fructus Forsythiae 13 parts, Radix Scutellariae 14 parts, Herba Verbenae 16 parts, Herba artemisiae lactiflorae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, Bai Guimu root 12 parts, 13 parts, Semen Persicae, Cortex Magnoliae Officinalis 8 parts, Radix Isatidis 11 parts, Bulbus Fritillariae Cirrhosae 8 parts, the Radix Astragali 7 parts, Pericarpium Citri Reticulatae 12 parts, 12 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 6 parts, Radix Gentianae Macrophyllae 5 parts, Flos Ilicis Asprellae 7 parts, Radix Notoginseng 13 parts, Fructus Ligustri Lucidi 17 parts, Herba Lysimachiae 10 parts, Rhizoma Sparganii 17 parts, Buddleja asiatica 3 parts, Spica Prunellae 12 parts, Radix Bupleuri 13 parts, Radix Gentianae 6 parts, Herba Artemisiae Scopariae 7 parts, Semen Plantaginis 6 parts, Radix Kansui 15 parts, 15 parts, the Radix Rehmanniae and Radix Puerariae 7 parts.

The preparation method of said medicine is as follows:

(1) according to above-mentioned weight by Herba Artemisiae Sieversianae, Parathelypteris glanduligera (Kunze) Ching, Herba Lamii Amplexicaulis, Radix Glycyrrhizae, Radix Knoxiae, Radix Achyranthis, the Rhizoma Atractylodis Macrocephalae, Semen sojae atricolor, Gryllotalpa, Herba Selaginellae Doederleinii, Fructus Forsythiae, Radix Scutellariae, Herba Verbenae, Herba artemisiae lactiflorae, Pseudobulbus Bletillae (Rhizoma Bletillae), Bai Guimu root, Semen Persicae, Cortex Magnoliae Officinalis, Radix Isatidis, Bulbus Fritillariae Cirrhosae, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Curcumae Longae, obstinate pudendal sore, Radix Gentianae Macrophyllae, Flos Ilicis Asprellae, Radix Notoginseng, Fructus Ligustri Lucidi, Herba Lysimachiae, Rhizoma Sparganii, Buddleja asiatica, Spica Prunellae, Radix Bupleuri, Radix Gentianae, Herba Artemisiae Scopariae, Semen Plantaginis, Radix Kansui, the Radix Rehmanniae and Radix Puerariae, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:6, soak 30 minutes in water.

(2) mixture in described step (1) and soak by water, after 60 minutes, are filtered and obtain the first filtrate and filtering residue.

(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:4, then decoct 80 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.

Embodiment 3

For a medicine for damp-heat type cirrhotic ascites, it comprises following component according to weight portion:

Herba Artemisiae Sieversianae 16 parts, Parathelypteris glanduligera (Kunze) Ching 17 parts, Herba Lamii Amplexicaulis 16 parts, 10 parts, Radix Glycyrrhizae, Radix Knoxiae 7 parts, Radix Achyranthis 30 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 30 parts, Semen sojae atricolor, Gryllotalpa 16 parts, Herba Selaginellae Doederleinii 20 parts, Fructus Forsythiae 20 parts, Radix Scutellariae 20 parts, Herba Verbenae 20 parts, Herba artemisiae lactiflorae 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Bai Guimu root 17 parts, 17 parts, Semen Persicae, Cortex Magnoliae Officinalis 12 parts, Radix Isatidis 17 parts, Bulbus Fritillariae Cirrhosae 10 parts, the Radix Astragali 10 parts, Pericarpium Citri Reticulatae 17 parts, 16 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 10 parts, Radix Gentianae Macrophyllae 7 parts, Flos Ilicis Asprellae 10 parts, Radix Notoginseng 16 parts, Fructus Ligustri Lucidi 20 parts, Herba Lysimachiae 16 parts, Rhizoma Sparganii 20 parts, Buddleja asiatica 5 parts, Spica Prunellae 17 parts, Radix Bupleuri 20 parts, Radix Gentianae 10 parts, Herba Artemisiae Scopariae 10 parts, Semen Plantaginis 10 parts, Radix Kansui 20 parts, 20 parts, the Radix Rehmanniae and Radix Puerariae 10 parts.

The preparation method of said medicine is as follows:

(1) according to above-mentioned weight by Herba Artemisiae Sieversianae, Parathelypteris glanduligera (Kunze) Ching, Herba Lamii Amplexicaulis, Radix Glycyrrhizae, Radix Knoxiae, Radix Achyranthis, the Rhizoma Atractylodis Macrocephalae, Semen sojae atricolor, Gryllotalpa, Herba Selaginellae Doederleinii, Fructus Forsythiae, Radix Scutellariae, Herba Verbenae, Herba artemisiae lactiflorae, Pseudobulbus Bletillae (Rhizoma Bletillae), Bai Guimu root, Semen Persicae, Cortex Magnoliae Officinalis, Radix Isatidis, Bulbus Fritillariae Cirrhosae, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Curcumae Longae, obstinate pudendal sore, Radix Gentianae Macrophyllae, Flos Ilicis Asprellae, Radix Notoginseng, Fructus Ligustri Lucidi, Herba Lysimachiae, Rhizoma Sparganii, Buddleja asiatica, Spica Prunellae, Radix Bupleuri, Radix Gentianae, Herba Artemisiae Scopariae, Semen Plantaginis, Radix Kansui, the Radix Rehmanniae and Radix Puerariae, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:6, soak 30 minutes in water.

(2) mixture in described step (1) and soak by water, after 60 minutes, are filtered and obtain the first filtrate and filtering residue.

(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:4, then decoct 80 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.

Certainly; more than illustrate and be only preferred embodiment of the present invention; the present invention is not limited to enumerate above-described embodiment; should be noted that; any those of ordinary skill in the art are under the instruction of this description; made all equivalently to substitute, obvious variant, within the essential scope all dropping on this description, protection of the present invention ought to be subject to.

Claims (2)

1., for a medicine for damp-heat type cirrhotic ascites, it comprises following component according to weight portion:

Herba Artemisiae Sieversianae 3 parts-16 parts, Parathelypteris glanduligera (Kunze) Ching 5 parts-17 parts, Herba Lamii Amplexicaulis 3 parts-16 parts, 5 parts-10 parts, Radix Glycyrrhizae, Radix Knoxiae 1 part-7 parts, Radix Achyranthis 5 parts-30 parts, the Rhizoma Atractylodis Macrocephalae 5 parts-30 parts, 5 parts-30 parts, Semen sojae atricolor, Gryllotalpa 3 parts-16 parts, Herba Selaginellae Doederleinii 5 parts-20 parts, Fructus Forsythiae 5 parts-20 parts, Radix Scutellariae 5 parts-20 parts, Herba Verbenae 15 parts-20 parts, Herba artemisiae lactiflorae 5 parts-20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts-20 parts, Bai Guimu root 5 parts-17 parts, 5 parts-17 parts, Semen Persicae, Cortex Magnoliae Officinalis 3 parts-12 parts, Radix Isatidis 5 parts-17 parts, Bulbus Fritillariae Cirrhosae 5 parts-10 parts, the Radix Astragali 5 parts-10 parts, Pericarpium Citri Reticulatae 5 parts-17 parts, 3 parts-16 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 5 parts-10 parts, Radix Gentianae Macrophyllae 1 part-7 parts, Flos Ilicis Asprellae 5 parts-10 parts, Radix Notoginseng 3 parts-16 parts, Fructus Ligustri Lucidi 15 parts-20 parts, Herba Lysimachiae 3 parts-16 parts, Rhizoma Sparganii 15 parts-20 parts, Buddleja asiatica 1 part-5 parts, Spica Prunellae 5 parts-17 parts, Radix Bupleuri 5 parts-20 parts, Radix Gentianae 5 parts-10 parts, Herba Artemisiae Scopariae 5 parts-10 parts, Semen Plantaginis 2 parts-10 parts, Radix Kansui 10 parts-20 parts, 10 parts-20 parts, the Radix Rehmanniae and Radix Puerariae 5 parts-10 parts.

2. medicine according to claim 1, is characterized in that, it comprises following component according to weight portion:

Herba Artemisiae Sieversianae 10 parts, Parathelypteris glanduligera (Kunze) Ching 11 parts, Herba Lamii Amplexicaulis 12 parts, 8 parts, Radix Glycyrrhizae, Radix Knoxiae 4 parts, Radix Achyranthis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 21 parts, Semen sojae atricolor, Gryllotalpa 12 parts, Herba Selaginellae Doederleinii 15 parts, Fructus Forsythiae 13 parts, Radix Scutellariae 14 parts, Herba Verbenae 16 parts, Herba artemisiae lactiflorae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, Bai Guimu root 12 parts, 13 parts, Semen Persicae, Cortex Magnoliae Officinalis 8 parts, Radix Isatidis 11 parts, Bulbus Fritillariae Cirrhosae 8 parts, the Radix Astragali 7 parts, Pericarpium Citri Reticulatae 12 parts, 12 parts, Rhizoma Curcumae Longae, obstinate pudendal sore 6 parts, Radix Gentianae Macrophyllae 5 parts, Flos Ilicis Asprellae 7 parts, Radix Notoginseng 13 parts, Fructus Ligustri Lucidi 17 parts, Herba Lysimachiae 10 parts, Rhizoma Sparganii 17 parts, Buddleja asiatica 3 parts, Spica Prunellae 12 parts, Radix Bupleuri 13 parts, Radix Gentianae 6 parts, Herba Artemisiae Scopariae 7 parts, Semen Plantaginis 6 parts, Radix Kansui 15 parts, 15 parts, the Radix Rehmanniae and Radix Puerariae 7 parts.