CN104922623A - Pomegranate bark composition for treating persistent dysentery and hematochezia - Google Patents

Pomegranate bark composition for treating persistent dysentery and hematochezia Download PDF

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Publication number
CN104922623A
CN104922623A CN201510242721.8A CN201510242721A CN104922623A CN 104922623 A CN104922623 A CN 104922623A CN 201510242721 A CN201510242721 A CN 201510242721A CN 104922623 A CN104922623 A CN 104922623A
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China
Prior art keywords
parts
pericarpium granati
pomegranate bark
dysentery
thin slice
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CN201510242721.8A
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Chinese (zh)
Inventor
刘长华
李澜
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Huaiyuan County Chaste Tree Tushan Pomegranate Science And Technology Ltd
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Huaiyuan County Chaste Tree Tushan Pomegranate Science And Technology Ltd
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Priority to CN201510242721.8A priority Critical patent/CN104922623A/en
Publication of CN104922623A publication Critical patent/CN104922623A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention provides a pomegranate bark composition for treating persistent dysentery and hematochezia, and relates to the technical field of traditional Chinese medicines and traditional Chinese medicine processing. The pomegranate bark composition is prepared from the following raw materials in parts by weight: 15 parts of pomegranate bark, 7 parts of Chinese mugwort leaf, 4 parts of dark plum fruit, oriental waterplantain rhizome, red dates, scorched hawthorn fruit, liquoric root, amomum fruit, cassia bark, 3 parts of indian buead, 6 parts of dangshen, 4 parts of astragalus, 2 parts of coptis root, 4 parts of Chinese mosla herb, 6 parts of hairyvein agrimonia herb and bud, 4 parts of apricot kernel and 5 parts of dried ginger, wherein the pomegranate bark is de-astringency pomegranate bark. The pomegranate bark composition for treating the persistent dysentery and hematochezia has a good treatment effect on bacterial intestinal inflammation, the bacterial intestinal inflammation is not easy to recur after being cured, the pomegranate bark in the composition is subjected to repeated de-astringency including the ways of infiltration separation, zymolysis and the like, and the aim of de-astringency of the pomegranate bark is achieved finally; meanwhile, the taste of the pomegranate bark is improved through honey and edible glycerin, and the medicine taking pain can be greatly alleviated.

Description

A kind of Pericarpium Granati compositions for the treatment of persistence dysentery, having blood in stool
Technical field:
The present invention relates to Chinese medicine and processing technique of Chinese herbs field, particularly relate to a kind of Pericarpium Granati compositions for the treatment of persistence dysentery, having blood in stool.
Background technology:
Diarrhoea is a kind of common sympton, is commonly called as " diarrhoea ", and refer to that defecation frequency is significantly more than the frequency be on ordinary days accustomed to, excrement matter is thin, and moisture increases, and every day, feces volume was more than 200g, or containing non-digest food or pus and blood, mucus.Diarrhoea is normal with symptoms such as defecation urgency sense, anus discomfort, incontinences.Diarrhoea point acute and chronic two classes.Sharply, the course of disease is within 2 ~ 3 weeks in acute diarrhea morbidity.Chronic diarrhea refers to that the course of disease is more than two months or the persistence dysentery of intermission in 2 ~ 4 weeks, to have blood in stool.
Although the medicine at present for diarrhea treatment is a lot, most drug effect measurement does not effect a permanent cure, and relapse rate is higher, needs a kind of specific medicament can effectively effect a radical cure above-mentioned disease.
Pericarpium Granati is a kind of Chinese medicine.For the peel of Punicaceae plant Punica granatum L., its sour in the mouth, puckery, bitter.Have relieving diarrhea with astringents, hemostasis, effect of anthelmintic, for chronic diarrhea, chronic dysentery, has blood in stool, proctoptosis, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation.Due to Pericarpium Granati bitter in the mouth, relate to, mouthfeel is bad, is directly used as medicine or adds in food or feedstuff, all can be difficult to swallow.
Summary of the invention:
The object of the present invention is to provide a kind of Pericarpium Granati compositions for the treatment of persistence dysentery, having blood in stool, to solve the problems of the technologies described above.
Technical problem to be solved by this invention realizes by the following technical solutions:
A Pericarpium Granati compositions of treat persistence dysentery, having blood in stool, is characterized in that, is prepared from by the raw material of Chinese medicine of following weight portion:
Pericarpium Granati 15 parts, Folium Artemisiae Argyi 7 parts, Fructus Mume 4 parts, Rhizoma Alismatis, Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Fructus Amomi, Cortex Cinnamomi, 3 parts, Poria, Radix Codonopsis 6 parts, the Radix Astragali 4 parts, Rhizoma Coptidis 2 parts, Herba Moslae 4 parts, Herba Agrimoniae 6 parts, 4 parts, Semen Armeniacae Amarum, Rhizoma Zingiberis 5 parts;
Pericarpium Granati after what wherein Pericarpium Granati was selected is debitterize is puckery, concrete steps are:
(1) collect the Pericarpium Granati stripped down, be immersed in the water and soak 6-8 hour, Pericarpium Granati is soaked into completely, and Pericarpium Granati is waterlogged, and can separate out bitter taste material, can strengthen quick-freezing effect simultaneously;
(2) Pericarpium Granati after soaking is placed in less than-10 DEG C environment quick-freezings; Cooling time is more than 2 hours, and through quick-freezing, Pericarpium Granati has enough hardness, just can cut out the thin slice met the demands;
(3) cut into slices to the Pericarpium Granati after freezing, slice thickness is not more than 0.8mm, makes Pericarpium Granati thin slice, thinly slices to be beneficial to bitter taste material and fully to separate out, and increases the area contacted with hydromel, the effect of raising rapid fermentation;
(4) by Pericarpium Granati thin slice warm water soaking, water temperature 38-45 DEG C, soaks 3-5min and takes out immediately;
(5) after Pericarpium Granati thin slice takes out, immerse in hydromel, make Pericarpium Granati thin slice be stained with hydromel can take out, be placed in the environment of 35 ± 2 DEG C, natural fermentation 16-20 hour, Pericarpium Granati thin slice is spread out, make its surperficial natural air drying, natural fermentation is the key reducing bitter taste material further, and fermentation can be utilized bitter taste substance decomposition, Mel composition is as sweeting agent simultaneously, can improve the palatability of Pericarpium Granati;
(6) after air-dry, at its surface-coated one deck edible glycerol, then with steam moisturizing 30min, edible glycerol can be used as sweeting agent, can avoid in steam moisturizing process simultaneously, and the active ingredient of Pericarpium Granati is run off.
The water that Pericarpium Granati uses is soaked in step (1), select light salt brine, light salt brine is dissolved in the water by Sal and is formed, Sal concentration of ordinary dissolution is 1.2g/L, light salt brine is used to soak the effect that can increase and remove Pericarpium Granati bitter taste, brine concentration is not easily excessive, avoids the effective ingredient destroying Pericarpium Granati.
In step (4) during Pericarpium Granati thin slice warm water soaking, can drip a small amount of white vinegar in warm water, white vinegar concentration is not more than 0.6g/L, drips a small amount of white vinegar in warm water, has the effect of softening Pericarpium Granati, can alleviate the bitter taste of Pericarpium Granati further simultaneously.
The invention has the beneficial effects as follows:
Treatment persistence dysentery provided by the invention, the Pericarpium Granati compositions of having blood in stool, be used for the treatment of persistence dysentery, good effect of having blood in stool, not easily recur after healing, Pericarpium Granati in compositions is through repeatedly debitterize is puckery, comprise and infiltrate the means such as precipitation, fermentation decomposition, finally reach the object that Pericarpium Granati debitterize is puckery, improved the mouthfeel of Pericarpium Granati simultaneously by Mel and edible glycerol, greatly can reduce the misery of taking medicine.
Detailed description of the invention:
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
A Pericarpium Granati compositions of treat persistence dysentery, having blood in stool, is characterized in that, is prepared from by the raw material of Chinese medicine of following weight portion:
Pericarpium Granati 15g, Folium Artemisiae Argyi 7g, Fructus Mume 4g, Rhizoma Alismatis, Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Fructus Amomi, Cortex Cinnamomi, Poria 3g, Radix Codonopsis 6g, Radix Astragali 4g, Rhizoma Coptidis 2g, Herba Moslae 4g, Herba Agrimoniae 6g, Semen Armeniacae Amarum 4g, Rhizoma Zingiberis 5g;
Pericarpium Granati after what wherein Pericarpium Granati was selected is debitterize is puckery, the concrete steps that Pericarpium Granati debitterize is puckery are:
Collect the Pericarpium Granati stripped down, be immersed in the water and soak 6-8 hour, Pericarpium Granati is soaked into completely, and Pericarpium Granati is waterlogged, and can separate out bitter taste material, can strengthen quick-freezing effect simultaneously;
Pericarpium Granati after immersion is placed in less than-10 DEG C environment quick-freezings; Cooling time is more than 2 hours, and through quick-freezing, Pericarpium Granati has enough hardness, just can cut out the thin slice met the demands;
Cut into slices to the Pericarpium Granati after freezing, slice thickness is not more than 0.8mm, makes Pericarpium Granati thin slice, thinly slices to be beneficial to bitter taste material and fully to separate out, and increases the area contacted with hydromel, the effect of raising rapid fermentation;
By Pericarpium Granati thin slice warm water soaking, water temperature 38-45 DEG C, soaks 3-5min and takes out immediately;
After Pericarpium Granati thin slice takes out, immerse in hydromel, make Pericarpium Granati thin slice be stained with hydromel can take out, be placed in the environment of 35 ± 2 DEG C, natural fermentation 16-20 hour, Pericarpium Granati thin slice is spread out, make its surperficial natural air drying, natural fermentation is the key reducing bitter taste material further, and fermentation can be utilized bitter taste substance decomposition, Mel composition is as sweeting agent simultaneously, can improve the palatability of Pericarpium Granati;
After air-dry, at its surface-coated one deck edible glycerol, then with steam moisturizing 30min, edible glycerol can be used as sweeting agent, can avoid in steam moisturizing process simultaneously, and the active ingredient of Pericarpium Granati is run off.
Clinical trial:
(1) clinical data
Applicant in 2010 so far, carries out clinical observation treatment to 100 routine persistence dysentery, the patient that has blood in stool, wherein man 66 example, female 34 example, and the age, between 17 ~ 58 years old, 28.7 years old mean age, medical history the shortest January, reaches more than 1 year most, recurrent exerbation.
(2) Therapeutic Method:
Adopt the compositions of the embodiment of the present invention 1, decocting for Chinese herbal medicine method routinely, with soak by water, filtering extracting liquid is oral, every day potion, points three times, one after each meal 7 days is a course for the treatment of.Calculate treatment time according to conditions of patients weight, patients with mild takes 1 ~ 2 course for the treatment of, and severe case serve on 3 ~ 4 courses for the treatment of and can fully recover.
(3) efficacy assessment standard:
The present invention is mainly used in treatment persistence dysentery, disease of having blood in stool, therefore symptom improvement situation and every Testing index are as curative effect judging standard, are divided into following four kinds:
Cure: suffer from abdominal pain, suffer from diarrhoea, transference cure of having blood in stool, stool is shaped, every day 1 ~ 2 time, and the primary symptom of TCM syndrome, secondary disease disappear, and tongue fur recovers normal substantially, and its relevant objective indicator of the disease relevant to diarrhoea is close to normally.
Effective: times of defecation every day 2 ~ 3 times, to be approximately shaped, or loose stool every day only once, the primary symptom of TCM syndrome, secondary disease improve degree more than 2 grades, and the objective indicator relevant to diarrhoea has clear improvement.
Effective: times of defecation and matter, primary symptom, the secondary disease of TCM syndrome are all taken a favorable turn, and the objective indicator relevant to diarrhoea take a favorable turn.
Invalid: symptom is without improvement or increase the weight of, the objective indicator relevant to diarrhoea is all without improving.
(4) therapeutic effect:
Clinical cure 73 example, effective 12 examples, effective 10 examples, invalid 5 examples, all cases all have no adverse reaction.
(5) sum up:
Clinical time: 4-5, curative effect: 8 days effectively, the course for the treatment of: general patient 15 days, symptom disappears substantially, patient with severe symptoms: within 20 days, disease disappears, and within 28 days, symptom all disappears.Effective percentage 95%, cure rate 73%.
The present invention prepares simply, and good absorbing effect is evident in efficacy, and have no side effect, safety is high, is conducive to sufferer and alleviates condition of illness in time.
More than show and describe ultimate principle of the present invention, principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description is only preference of the present invention; be not used for limiting the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.

Claims (3)

1. a Pericarpium Granati compositions of treat persistence dysentery, having blood in stool, is characterized in that, is prepared from by the raw material of Chinese medicine of following weight portion:
Pericarpium Granati 15 parts, Folium Artemisiae Argyi 7 parts, Fructus Mume 4 parts, Rhizoma Alismatis, Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Fructus Amomi, Cortex Cinnamomi, 3 parts, Poria, Radix Codonopsis 6 parts, the Radix Astragali 4 parts, Rhizoma Coptidis 2 parts, Herba Moslae 4 parts, Herba Agrimoniae 6 parts, 4 parts, Semen Armeniacae Amarum, Rhizoma Zingiberis 5 parts;
Pericarpium Granati after what wherein Pericarpium Granati was selected is debitterize is puckery, concrete steps are:
(1) collect the Pericarpium Granati stripped down, be immersed in the water and soak 6-8 hour, Pericarpium Granati is soaked into completely;
(2) Pericarpium Granati after soaking is placed in less than-10 DEG C environment quick-freezings; Cooling time is more than 2 hours;
(3) cut into slices to the Pericarpium Granati after freezing, slice thickness is not more than 0.8mm, makes Pericarpium Granati thin slice;
(4) by Pericarpium Granati thin slice warm water soaking, water temperature 38-45 DEG C, soaks 3-5min and takes out immediately;
(5), after Pericarpium Granati thin slice takes out, immerse in hydromel, making Pericarpium Granati thin slice be stained with hydromel can take out, and be placed in the environment of 35 ± 2 DEG C, natural fermentation 16-20 hour, spreads out Pericarpium Granati thin slice, makes its surperficial natural air drying;
(6) after air-dry, at its surface-coated one deck edible glycerol, then with steam moisturizing 30min.
2. treatment persistence dysentery according to claim 1, the Pericarpium Granati compositions of having blood in stool, it is characterized in that, soak the water that Pericarpium Granati uses in step (1), select light salt brine, light salt brine is dissolved in the water by Sal and is formed, and Sal concentration of ordinary dissolution is 1.2g/L.
3. treatment persistence dysentery according to claim 1, the Pericarpium Granati compositions of having blood in stool, is characterized in that, in step (4) during Pericarpium Granati thin slice warm water soaking, can drip a small amount of white vinegar in warm water, white vinegar concentration is not more than 0.6g/L.
CN201510242721.8A 2015-05-13 2015-05-13 Pomegranate bark composition for treating persistent dysentery and hematochezia Pending CN104922623A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105396034A (en) * 2015-11-30 2016-03-16 王平平 Medicine for amebic dysentery

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829244A (en) * 2010-05-10 2010-09-15 曹建欣 Traditional Chinese medicine for treating enteritis and colonitis
CN102524691A (en) * 2011-03-17 2012-07-04 浙江省常山宝新果蔬菌有限公司 Preparation method of Citrus huyou chips

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829244A (en) * 2010-05-10 2010-09-15 曹建欣 Traditional Chinese medicine for treating enteritis and colonitis
CN102524691A (en) * 2011-03-17 2012-07-04 浙江省常山宝新果蔬菌有限公司 Preparation method of Citrus huyou chips

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张红昌等: "补气活血通络方配合头针治疗慢性非特异性溃疡性结肠炎50例", 《河北中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105396034A (en) * 2015-11-30 2016-03-16 王平平 Medicine for amebic dysentery

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Application publication date: 20150923

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