CN105640675A - 具有可扩展的固定装置的脊柱植入物 - Google Patents

具有可扩展的固定装置的脊柱植入物 Download PDF

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Publication number
CN105640675A
CN105640675A CN201510859939.8A CN201510859939A CN105640675A CN 105640675 A CN105640675 A CN 105640675A CN 201510859939 A CN201510859939 A CN 201510859939A CN 105640675 A CN105640675 A CN 105640675A
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CN
China
Prior art keywords
parts
stretch
implant
vertebral body
expanded according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510859939.8A
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English (en)
Inventor
R.T.格罗茨
R.A.普雷蒂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Howmedica Leibinger Inc
Coalign Innovations Inc
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Howmedica Leibinger Inc
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Publication of CN105640675A publication Critical patent/CN105640675A/zh
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    • A61F2250/0004—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/0009—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting thickness
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys

Abstract

本发明涉及一种脊柱植入物，其被构造成在相邻椎骨体之间展开。该植入物具有至少一个固定元件(18,19)，所述固定元件具有用以方便植入物展开的缩回构造和用以接合相邻椎骨体的表面并将植入物固定在两个椎骨体之间的伸展构造。优选地，植入物是可扩展的并且在其未扩展状态下具有小于神经孔尺寸的最小尺寸，植入物必须穿过该神经孔以在椎骨间空间内展开。一旦处于椎骨体之间的空间内，植入物就可以扩展以便接合相邻椎骨的端板，从而有效地牵引前部椎骨间盘空间、固定运动节段并阻止病理脊柱运动。可以矫正角畸形，并且恢复和保持自然曲率。

Description

具有可扩展的固定装置的脊柱植入物
本申请是一项发明申请的分案申请，其母案的发明名称是具有可扩展的固定装置的脊柱植入物，申请日是2009年2月17日，申请号是200980106122.6（国际申请号：PCT/US2009/000974）。
技术领域
本发明涉及用于稳定椎骨运动节段(vertebralmotionsegment)的装置和方法。更具体而言，本发明的领域涉及一种具有固定元件的可扩展脊柱植入物以将植入物固定在椎骨间空间内，同时提供三维受控脊柱矫正以改进脊柱的椎骨体间牵引和融合。
背景技术
常规的椎骨间保持架(cage)或植入物的特征在于具有菜豆形本体，该本体通常在试用植入物形成路径之后从后部纵排地插穿过被牵引脊柱的神经孔(neuroforamen)。用于使体间(interbody)稳定的现有设备存在重大且明显的限制，这些限制包括无法对端板进行扩展和牵引，同时将设备固定以阻止设备与相邻的椎骨体之间的相对运动。目前的用于使体间稳定的设备包括静态隔离件，这些静态隔离件包括钛、PEEK和由VICTREX(VictrexUSAInc,3ACaledonCourt;Greenville,SC29615)生产的高性能热塑性聚合物、碳纤维或者可吸收聚合物。此外，目前的体间隔离件无法保持体间脊柱前凸并且会导致形成直的或者甚至脊柱后凸的节段，并且带来了“平背综合症(flatbacksyndrome)”等临床问题。椎骨端板之间的分离增加了神经元、特别是神经孔可利用的空间。现有的静态保持器无法可靠地增加神经元的空间。因此，需要提供一种脊柱植入物，其将会从后部提供椎骨体之间的用于神经元的空间，或至少能保持自然骨骼的轮廓以避免出现神经失用症(神经牵拉)或侵占。
常规的用于使椎骨体间稳定的设备包括在骨与设备的生物材料之间的不良界面(interface)。常规的静态体间间隔件在骨与生物材料之间形成了不牢固的界面。尽管此类植入物的表面通常设有一系列脊部或涂覆有羟基磷灰石，但这些脊部会平行于所施加的水平矢量或左右运动。即，植入物上的脊部或涂层对于施加到端板任一侧上的移动没有提供多少阻力。这样，由于植入物与宿主骨之间的运动，使得在同种异体移植物、钛和聚合物隔离件中普遍出现骨不连合(nonunion)。
发明内容
本发明总体上涉及一种用于在部分或完全取下椎骨间盘后插入在上部椎骨端板与下部椎骨端板之间的脊柱植入物。体现本发明特征的脊柱植入物容易被安装并能够以增加的拔出强度保持椎骨或关节节段，以在将植入物引入关节固定术骨块内的时间段将植入物固定损失的几率降到最小。
更具体而言，本发明特别涉及一种脊柱植入物，其具有接合或刺入椎骨端板并阻止移植后在植入物与椎骨端板之间的运动的一个或多个可伸展的固定元件。所述一个或多个可伸展的固定元件在植入物内具有收缩构造以便不会与植入物在椎骨体之间的插入相干涉，并且具有伸展构造，远端(distaltip)伸出植入物的表面以在移植后接合椎骨端板并且相对于相邻的椎骨体固定植入物的位置。固定元件可通过各种方式伸展，比如通过流体压力，例如液压流体；通过机械力，比如与旋转驱动部件或其它合适的装置进行螺纹连接。优选流体移置。固定元件的远端应当足够锋利以刺入椎骨端板内。
优选地，体现本发明特征的脊柱植入物是可扩展的脊柱植入物，比如于2006年9月26日提交的序号为11/535,432和于2007年3月28日提交的序号为11/692,800的共同未决申请中所述的选择性扩展的椎骨间保持器，其提供了相邻椎骨之间的椎骨间盘高度的恢复并且可提供多维的矫正性脊柱序列。优选地，该植入物具有用于接纳骨传导材料以促进紧随移植之后椎骨间空间内新骨的形成。
具有本发明特征的脊柱植入物具有包括第一压力施加部件(比如具有第一骨接合表面的端板)的基部、与该基部配合的至少一个可伸展的部件、以及具有第二骨接合表面的第二上部压力施加部件，该第二骨接合表面被联接至所述至少一个可伸展的部件。所述一个或多个可伸展的固定元件被构造成伸展穿过设置在第二上部压力施加部件中的通道并超出其骨接合表面以刺入相邻的椎骨端板内并且相对于椎骨体固定植入物。优选地，固定元件以可滑动方式布置在可伸展的部件内的凹部内。
体现本发明的特征的选择性扩展的椎骨间保持器(spinecage,SEC)或脊柱植入物特别适合从后部插入上部椎骨端板与下部椎骨端板之间，如前述序号为11/535,432和11/692,800的共同未决申请中所述。SEC具有允许容易展开的未扩展构造并且最短横向尺寸通常为约0.8至约1cm以便能够以侵入性最小的方式从后部在椎弓根之间插穿直径大约为1cm的工作空间。伸展的固定元件伸出第二压力施加部件的组织接合表面至少0.1cm，优选地至少0.25cm，以确保与椎骨体的端板进行适当接合或接触并且优选其刺入。
在一个优选实施例中，至少一个且优选SEC的可伸展的部件全部具有布置在可伸展的部件中凹部内的可伸展的固定元件。在本实施例中，植入物优选地被流体激活使得可伸展的部件在移植之后使SEC扩展并被适当定位在相邻的椎骨体之间。另外，固定部件还随同SEC的扩展或在SEC的扩展之后通过流体压力伸展。优选地，流体扩展借助于来自位于远离病人位置处的主缸或注射器的液压流体以实现多维的受控脊柱校正和SEC在适当位置的固定。也可以采用单独的缸或注射器。有利地，液压流体是受时间控制的可固化聚合物，比如甲基丙烯酸甲酯，该聚合物具有如众所周知具有可以通过配制适当添加催化剂来调节的粘性和固化时间。当聚合物固化时，该聚合物使伸展的可伸展的部件和扩展的固定元件硬化并且将它们固定地锁定在适当位置处以提供所需的前部/后部、中间/侧部、上部/下部脊柱矫正量。也可以采用可扩展的部件和/或固定元件的机械锁定。
一旦被插入椎骨端板之间，则植入物有利地借助于最小的力就可以产生扩展，该力是通过液压控制管线在远程施加的。植入物的扩展有利地比其未扩展高度大约20%至约100%，通常约60%。典型扩展在8mm植入物的情况下为约13mm，而在10mm植入物的情况下则为约16mm。
由于椎骨端板在一端(前端)处借助于非常类似于蛤壳的韧带被保持在一起，所以随着植入物抵靠椎骨端板扩展，可对垂直扩展量进行调节以形成所需的前部/后部矫正角度。
脊柱的左侧矫正和右侧矫正是通过植入物的两个或更多个可伸展的部件的不同垂直扩展而实现的。每个可伸展的部件优选地受到主缸或注射器的独立控制，该主缸或注射器位于体外(位于远离病人的位置处)且与辅助缸进行液压传递(hydrauliccommunication)以使活塞和顶板进行垂直和横向移动，以便从前部或后部、从中间或从侧部对脊柱畸形进行矫正，从而提供三维脊柱矫正。
使侵入性降至最小的小型插入工具既从后部插入未扩展的SEC又罩住了在主缸与辅助缸之间进行连通的液压管线。该插入工具还罩住了用于将液态或浆料态的骨移植材料连通至辅助缸并连通进入椎骨间空间内以便随后融合的管线。有利地，这些液压管线是小尺寸管道以允许可以采用高液压压力而不会出现管线破裂的危险。辅助缸和活塞的尺寸可以产生变化以便增加机械优点。
由于液压系统提供了机械优点，所以SEC在其未扩展的状态下具有最小化的尺寸和直径，该尺寸和直径小于制备的神经孔的直径。SEC因此可从后部被插入且被接合在相邻椎骨的端板之间以便有效地牵引椎骨间区域、恢复用于神经元的空间、稳定运动节段、并阻止病理节段的运动。该SEC通过形成刚性脊柱节段而促进了脊柱关节固定术。
该SEC使得能够将相对大量的骨生长传导剂或诱导剂包含在该SEC内部并与相邻骨直接连通，这是一个显著的优点。重要的是，这导致产生了比相邻骨和软组织失效力更大的固定力。
该液压控制系统通过使得外科医生能够在远离病人身体位置处施加控制力而在三维方向上扩展并调节脊柱植入物而提供了使侵入性降至最小的过程。优选地，该扩展是无限可调的以便提供各种高度和横向角度，且不限于增量位置。该植入物可用来促进融合，和/或矫正诸如脊柱侧凸、脊柱后凸和脊椎前移之类的畸形。
SEC及其插入方法的临床目标将神经根受损的侵入性风险降至最小、减轻了痛苦、改善了功能且使得可在融合手术之后对病人进行早期固定。固定元件将植入物保持在所需的位置直到愈合(融合或关节固定术)出现为止。此时，植入物被结合在骨内部且其作用变成静止作用。本发明的SEC提供了更多的内部和外部移植骨空间暴露程度、使得更易于实现定向插入同时更为安全、降低了对神经根和其它组织造成插入损伤的风险、且因此显著改善了中长期治疗效果。
因此，本发明的一个关键特征在于，实质上不可压缩的植入物可以在仅1cm工作空间内从后部插入椎弓根之间。植入物然后可被扩展至其原始插入尺寸的约100%至约200%，通常约160%，以便提供严格受控的全方位三维脊柱矫正。所述一个或更多个可伸展的固定元件或钉确保植入物在展开之后保持在适当位置。本发明的这些和其它优点将从以下详细描述并从示例性附图变得更加明显。
附图说明
图1描绘出体现本发明的特征的SEC在相邻的腰椎之间的安放情况。
图2是图1中所示的SEC处于展开之前的未扩展状态下的前部透视图。
图3是图2中所示的SEC的剖视图。
图4是类似于图2中所示的SEC处于扩展构造中的前部透视图。
图5是图4中所示的扩展的SEC在与椎骨体相邻位置处的部分剖视图，固定部件的尖端刺入椎骨体的表面。
具体实施方式
图1图示出在扩展构造中脊柱植入物或SEC10在相邻的腰椎之间的位置。在插入脊柱植入物10之前以常规的方式实施了部分或完全的椎骨间盘切除术。SEC10在其未扩展状态下被导入以使其能够在病人受外伤和神经根受伤的风险最小的情况下从后部插入。一旦就位，就可以使SEC10扩展以既提供中间脊柱矫正又提供侧部脊柱矫正。SEC具有约5至约15mm、通常约10mm的未扩展高度，并且可扩展至未扩展高度的至少130%至约180%。通常，SEC宽约9至约15mm，通常约12mm；并且长约25至约40mm，通常约28mm，以有利于从后部插入，并从而将病人受外伤和神经根受伤的风险降至最小。
图2-3图示出处于封闭或未扩展构造中的SEC10，并且图4以剖面图或剖视图图示出处于扩展构造中的SEC10以示出内部结构。
如这些图中所示，SEC10具有基部12，该基部12具有压力施加端部件或板13，该压力施加端部件或板13具有用于接合相邻椎骨体的端面的表面14。可伸展的支承部件15和16与基部12配合。第二端压力施加部件或板17联接于可伸展的支承部件15和16，使得板17随同可伸展的支承部件15和16的伸展而移动。板17不但可以仅被固定于可伸展的支承部件中的一个，而且可与另一个可伸展的支承部件接合。每个可伸展的支承部件可具有固定于其上的单独端板。如图3中更详细地示出，可伸展的支承部件15和16设有以可滑动方式布置在可伸展的支承部件15和16的孔20和21内的固定元件或钉18和19。钉18和19设有扩大基部22和23，扩大基部22和23为孔20和21提供密封。该密封允许钉18和19通过使可伸展的支承部件15和16伸展的相同加压液压流体(未示出)而伸展。钉18和19设有尖远端22和23，尖远端22和23延伸穿过设置在端压力板17内的通道24和25，以确保这些钉与相邻椎骨体之间如图5中所示进行接触以便将SEC10固定在相邻椎骨体之间的空间内。在图5中，SEC10被示出处于扩展构造中。SEC10具有中心腔体27，用于当SEC完全扩展时或者在扩展期间将骨移植材料灌入椎骨间空间内。
SEC的另外细节，比如液压管线和用于传输浆料态或液态骨移植材料的管线的附属装置、设备和液压流体传送附件等，可在于2006年9月26日提交的序号为11/535,432和于2007年3月28日提交的序号为11,692,800的共同未决申请中找到，在此通过引用将其并入。
由于椎骨端板在一端处借助于非常类似于蛤壳的韧带被保持在一起，所以可以对设备10抵靠相邻椎骨体的端板的扩展进行调节以形成所需的前部/后部矫正角度。
用来使SEC10扩展以及使钉18和19伸展的液压流体可以有利地是受时间控制的可固化聚合物，比如甲基丙烯酸甲酯。如众所周知的，可以通过配制适当添加的催化剂来调节此类聚合物的粘性和固化时间。此类催化剂可以从LOCTITECorp.,1001TroutBrookCrossing,RockyHill,Connecticut06067获得。当聚合物固化时，该聚合物使可伸展的部件15和16以及钉18和19硬化并将它们锁定在所需位置处以提供由医师确定的所需的脊柱矫正量。可以采用其它装置来将可伸展的部件和钉锁定在所需位置处。例如，可以在一个或多个活塞的孔、以及钉的一个或多个孔内设置弹簧致动的锁定指形件，这些锁定指形件当活塞或钉在其伸展后经过它们的相应部位时向外伸展。
可以理解的是，SEC，包括它的各种构件，应当由生物相容、基本上不可压缩的材料形成，比如钛，并且优选6-4型钛合金或者其它的将允许在病人体内长期布置的适当材料。
可伸展的部件15和16的伸展优选地是被单独控制，使得医师能够提供SEC矫正表面的受控角度。虽然在此仅描述了两个可伸展的部件，但SEC10可以被设有三个或更多个单独的可伸展的部件，使得医师可对SEC伸展进行三维控制。
体现本发明特征的SEC10提供了多个优点，包括：冠状面畸形的校正；体间脊柱前凸的引导；以大于目前间隔设备的刚性提早固定体间空间；以及将SEC固定在椎骨间空间内的能力。这种提早稳定可以改善术后疼痛，排除对包括椎弓根螺钉的后期植入物的需要，并且提高关节固定术的成功率。重要的是，SEC提供了神经元可获得的空间的改善，同时改善脊柱前凸。当被灌入的骨诱导/骨传导骨移植材料进行愈合时，病人变得康复并且植入物变成惰性和静止态，被埋置在骨内且不再被需要。
尽管已结合目前被认为最实用也最优选的实施例对本发明进行了描述，但应该理解的是，本发明并不限于如上所述被披露的实施例和备选方案，而是相反地旨在涵盖被包括在以下权利要求的范围内的各种变型和等效设置。
例如，文中所述的SEC10是通过液压流体进行扩展的。可以采用其它扩展装置。例如，可以采用螺丝机构来使SEC扩展并且使一个或多个钉伸展与相邻的椎骨表面接合。另外，有助于将SEC固定在椎骨空间内的钉在文中被描述为随同可伸展的支承部件延伸。但是，可以以可滑动方式将这些钉布置在单独的孔内并通过独立于可伸展的支承部件的扩展装置的装置进行伸展。
进一步地，SEC可以设有载荷或压力传感器，这些载荷或压力传感器记录由病人的椎骨端板施加在SEC的接合表面上的不同压力和压力密度以产生矫正信号，例如是通过计算机控制实现的，这种计算机控制例如由外科医生或受计算机控制的机构来使病人的脊柱重新对齐。本发明可进一步包括使这些调节实时且连续地响应于传感器信号的系统，从而使得植入物的形状发生变化以使病人的脊柱或机构重新对齐。优选地，这种系统被预想用来在植入物的安装期间设置活塞的位置。
此外，SEC无需被刚性地锁定在适当位置处，而是可以设有可屈服材料以提供SEC的端面的一些移动来接纳脊柱的移动。
尽管文中已示出和描述本发明的具体形式，但显然可对本发明作出各种改型和改进。可在文中引用的专利和申请中找到脊柱移植设备的另外的细节。以在文中未以别的方式进行披露为限，材料和结构可属于常规的设计。
此外，本发明的实施例的单独特征可能在一些图中被示出而在其它图中未被示出，但本领域的技术人员应该认识到，本发明的一个实施例的单独特征可以与另一实施例的任何或所有特征相结合。因此，本发明并非旨在受限于所示的特定实施例。因此，本发明旨在通过所附权利要求在现有技术许可情况下尽可能宽泛的范围来进行限定。
用语如“元件”、“部件”、“构件”、“设备”、“装置”、“部分”、“区段”、“步骤”和类似含义的词语当在文中使用时不应当被解释为调用了美国法典第35编第112(6)条款的规定，除非以下权利要求清楚地使用接以特定功能的用语“用于…的装置”或“用于…的步骤”而未参照具体的结构或具体的动作。在此通过引用并入以上提到的所有专利和所有专利申请的全文。

Claims (10)

1.一种可扩展的植入物，其包括：
第一部件，其具有用于接合第一椎骨体的第一接触表面；
第二部件，其具有用于接合第二椎骨体的第二接触表面；
至少两个可伸展的部件，其每一个被构造成当所述第一接触表面和所述第二接触表面各自与所述第一椎骨体和所述第二椎骨体中的一个接触时，使所述第一部件和所述第二部件中的至少一个从收缩构造伸展至伸展构造；以及
至少两个可伸展的固定元件，其具有被构造成刺入椎骨体的远端，所述至少两个可伸展的固定元件具有收缩构造和伸展构造，所述收缩构造用以方便所述植入物在所述第一椎骨体和所述第二椎骨体之间展开，所述伸展构造使所述远端伸展进入所述第二椎骨体，
其中所述至少两个可伸展的固定元件独立于所述至少两个可伸展的部件。
2.根据权利要求1所述的可扩展的植入物，其中所述至少两个可伸展的部件和所述至少两个可伸展的固定元件适合通过流体进行伸展。
3.根据权利要求1所述的可扩展的植入物，其中，所述至少两个可伸展的固定元件可独立于所述至少两个可伸展的部件进行伸展。
4.根据权利要求1所述的可扩展的植入物，其中，所述第二部件具有至少一个通道，所述至少两个固定元件中的每一个固定元件的远端伸展穿过所述至少一个通道以接合所述第二椎骨体。
5.根据权利要求2所述的可扩展的植入物，其中，所述流体包括可固化的聚合物，所述可固化的聚合物具有用于提供机械力的液压传递以使所述至少两个可伸展的部件伸展的流体状态、以及使所述至少两个可伸展的部件锁定在伸展构造中的固态和提供所述可扩展的植入物在扩展构造中有限移动的半固态中的至少一个。
6.根据权利要求2所述的可扩展的植入物，其中，所述至少两个可扩展的部件各自均包括缸内的活塞。
7.根据权利要求1所述的可扩展的植入物，其中所述至少两个可伸展的固定元件各自以可滑动方式布置在单独的孔中并且可独立于彼此进行伸展。
8.根据权利要求1所述的可扩展的植入物，其中，所述可伸展的部件被横向隔开，以限定在横向隔开的可伸展的部件和所述第一和第二部件之间的中心腔体。
9.根据权利要求1所述的可扩展的植入物，所述可扩展的植入物进一步包括可致动的锁定指形件以使所述至少两个可伸展的部件锁定在伸展状态中。
10.根据权利要求1所述的可扩展的植入物，其中，所述至少两个可伸展的部件可独立地伸展至所述第一部件上方的多个高度。
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107485470A (zh) * 2017-09-12 2017-12-19 张坤 一种医用骨科颈椎椎间隙动态稳定植入装置
CN107865714A (zh) * 2016-09-22 2018-04-03 劳伯特·S·萨德达比 可扩展椎间融合植入件
CN111432741A (zh) * 2017-09-01 2020-07-17 斯皮诺洛吉克斯公司 脊柱矫正棒植入物制造过程部分
CN112153951A (zh) * 2018-03-06 2020-12-29 Eit 新兴移植技术股份有限公司 具有集成伸展和角度调节机构的椎间笼
CN117204990A (zh) * 2023-11-09 2023-12-12 北京爱康宜诚医疗器材有限公司 一种寰枢椎侧块关节融合器

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2897259B1 (fr) 2006-02-15 2008-05-09 Ldr Medical Soc Par Actions Si Cage intersomatique transforaminale a greffon de fusion intervetebrale et instrument d'implantation de la cage
ES2547532T3 (es) 2004-02-04 2015-10-07 Ldr Medical Prótesis de disco intervertebral
US8114158B2 (en) * 2004-08-03 2012-02-14 Kspine, Inc. Facet device and method
US8597360B2 (en) * 2004-11-03 2013-12-03 Neuropro Technologies, Inc. Bone fusion device
FR2891135B1 (fr) 2005-09-23 2008-09-12 Ldr Medical Sarl Prothese de disque intervertebral
US7985256B2 (en) * 2005-09-26 2011-07-26 Coalign Innovations, Inc. Selectively expanding spine cage, hydraulically controllable in three dimensions for enhanced spinal fusion
US9028550B2 (en) 2005-09-26 2015-05-12 Coalign Innovations, Inc. Selectively expanding spine cage with enhanced bone graft infusion
US8070813B2 (en) * 2005-09-26 2011-12-06 Coalign Innovations, Inc. Selectively expanding spine cage, hydraulically controllable in three dimensions for vertebral body replacement
FR2916956B1 (fr) 2007-06-08 2012-12-14 Ldr Medical Cage intersomatique,prothese intervertebrale,dispositif d'ancrage et instrumentation d'implantation
US8591587B2 (en) 2007-10-30 2013-11-26 Aesculap Implant Systems, Llc Vertebral body replacement device and method for use to maintain a space between two vertebral bodies within a spine
US8182537B2 (en) 2007-10-30 2012-05-22 Aesculap Implant Systems, Llc Vertebral body replacement device and method for use to maintain a space between two vertebral bodies within a spine
US8142441B2 (en) * 2008-10-16 2012-03-27 Aesculap Implant Systems, Llc Surgical instrument and method of use for inserting an implant between two bones
US8932355B2 (en) 2008-02-22 2015-01-13 Coalign Innovations, Inc. Spinal implant with expandable fixation
US20100145455A1 (en) * 2008-12-10 2010-06-10 Innvotec Surgical, Inc. Lockable spinal implant
US8696751B2 (en) * 2008-12-10 2014-04-15 Coalign Innovations, Inc. Adjustable distraction cage with linked locking mechanisms
US8992620B2 (en) 2008-12-10 2015-03-31 Coalign Innovations, Inc. Adjustable distraction cage with linked locking mechanisms
US8216317B2 (en) 2008-03-31 2012-07-10 Stryker Spine Spinal implant apparatus and methods
US8142435B2 (en) 2009-02-19 2012-03-27 Aesculap Implant Systems, Llc Multi-functional surgical instrument and method of use for inserting an implant between two bones
US8641766B2 (en) 2009-04-15 2014-02-04 DePuy Synthes Products, LLC Arcuate fixation member
US9408715B2 (en) 2009-04-15 2016-08-09 DePuy Synthes Products, Inc. Arcuate fixation member
WO2010129697A1 (en) 2009-05-06 2010-11-11 Thibodeau Lee L Expandable spinal implant apparatus and method of use
US8529628B2 (en) 2009-06-17 2013-09-10 Trinity Orthopedics, Llc Expanding intervertebral device and methods of use
BR112012005663A2 (pt) * 2009-09-17 2021-07-27 Synthes Gmbh implante intervertebral com membros de fixação óssea expansíveis
US9078766B2 (en) 2012-07-06 2015-07-14 Intel Corporation Device and method with power efficient location notification function by periodically deactivating signal-based location service during travel until a wake trigger condition is met
US8685098B2 (en) 2010-06-25 2014-04-01 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US11344430B2 (en) 2009-10-15 2022-05-31 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US11103366B2 (en) 2009-10-15 2021-08-31 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US10098758B2 (en) 2009-10-15 2018-10-16 Globus Medical, Inc. Expandable fusion device and method of installation thereof
CN102781373B (zh) 2009-12-31 2016-10-26 Ldr医疗公司 锚定装置、椎间植入物和植入器械
US8353963B2 (en) * 2010-01-12 2013-01-15 Globus Medical Expandable spacer and method for use thereof
US9913726B2 (en) 2010-02-24 2018-03-13 Globus Medical, Inc. Expandable intervertebral spacer and method of posterior insertion thereof
AU2011227293A1 (en) 2010-03-16 2012-11-08 Pinnacle Spine Group, Llc Intervertebral implants and graft delivery systems and methods
US8317866B2 (en) * 2010-06-02 2012-11-27 Warsaw Orthopedic, Inc. System and methods for a laterally expanding implant
US9597200B2 (en) 2010-06-25 2017-03-21 Globus Medical, Inc Expandable fusion device and method of installation thereof
US9566168B2 (en) 2010-09-03 2017-02-14 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US10835387B2 (en) 2010-09-03 2020-11-17 Globus Medical Inc. Expandable fusion device and method of installation thereof
US8858637B2 (en) 2010-09-30 2014-10-14 Stryker Spine Surgical implant with guiding rail
US20140207239A1 (en) * 2011-09-09 2014-07-24 Spine Wave, Inc. Lateral approach expandable spinal implant and method
US8864833B2 (en) 2011-09-30 2014-10-21 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
US9693876B1 (en) 2012-03-30 2017-07-04 Ali H. MESIWALA Spinal fusion implant and related methods
US9622876B1 (en) 2012-04-25 2017-04-18 Theken Spine, Llc Expandable support device and method of use
US9510955B2 (en) 2012-05-18 2016-12-06 Trinity Orthopedics, Llc Articulating interbody cage and methods thereof
US9445918B1 (en) 2012-10-22 2016-09-20 Nuvasive, Inc. Expandable spinal fusion implants and related instruments and methods
US10350081B2 (en) 2012-12-11 2019-07-16 Globus Medical, Inc. Expandable vertebral implant
US9011493B2 (en) 2012-12-31 2015-04-21 Globus Medical, Inc. Spinous process fixation system and methods thereof
WO2014124453A2 (en) * 2013-02-11 2014-08-14 Brian Burkinshaw Unitary spinal disc implant
US9408711B2 (en) 2013-03-14 2016-08-09 Brian D. Burkinshaw Unitary spinal disc implant
US9782265B2 (en) 2013-02-15 2017-10-10 Globus Medical, Inc Articulating and expandable vertebral implant
US9204972B2 (en) 2013-03-01 2015-12-08 Globus Medical, Inc. Articulating expandable intervertebral implant
US10004607B2 (en) 2013-03-01 2018-06-26 Globus Medical, Inc. Articulating expandable intervertebral implant
US9456908B2 (en) 2013-03-12 2016-10-04 Coorstek Medical Llc Fusion cage
WO2014159739A1 (en) 2013-03-14 2014-10-02 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems
US9795493B1 (en) 2013-03-15 2017-10-24 Nuvasive, Inc. Expandable intervertebral implant and methods of use thereof
US9233009B2 (en) 2013-03-15 2016-01-12 Globus Medical, Inc. Expandable intervertebral implant
US9186258B2 (en) 2013-03-15 2015-11-17 Globus Medical, Inc. Expandable intervertebral implant
US10098757B2 (en) 2013-03-15 2018-10-16 Neuropro Technologies Inc. Bodiless bone fusion device, apparatus and method
FR3005569B1 (fr) 2013-05-16 2021-09-03 Ldr Medical Implant vertebral, dispositif de fixation vertebrale d'implant et instrumentation d'implantation
US9566167B2 (en) 2013-08-22 2017-02-14 K2M, Inc. Expandable spinal implant
JP6546918B2 (ja) 2013-11-27 2019-07-17 ハウメディカ・オステオニクス・コーポレイション 脊椎融合ケージのためのインサート支持構造体
US9980715B2 (en) 2014-02-05 2018-05-29 Trinity Orthopedics, Llc Anchor devices and methods of use
US9839528B2 (en) 2014-02-07 2017-12-12 Globus Medical, Inc. Variable lordosis spacer and related methods of use
USD764666S1 (en) 2014-02-10 2016-08-23 Brian D. Burkinshaw Unitary spinal disc implant
USD753306S1 (en) 2014-02-10 2016-04-05 Brian D. Burkinshaw Spinal disc implant with conic protrusions
US9456817B2 (en) 2014-04-08 2016-10-04 DePuy Synthes Products, Inc. Methods and devices for spinal correction
FR3020756B1 (fr) 2014-05-06 2022-03-11 Ldr Medical Implant vertebral, dispositif de fixation vertebrale d'implant et instrumentation d'implantation
US10363142B2 (en) 2014-12-11 2019-07-30 K2M, Inc. Expandable spinal implants
US9901459B2 (en) 2014-12-16 2018-02-27 Globus Medical, Inc. Expandable fusion devices and methods of installation thereof
US10765532B2 (en) 2015-05-21 2020-09-08 Globus Medical, Inc. Device and method for deployment of an anchoring device for intervertebral spinal fusion
US10433975B2 (en) 2015-05-21 2019-10-08 Globus Medical, Inc. Device and method for deployment of an anchoring device for intervertebral spinal fusion
US10376378B2 (en) 2015-05-21 2019-08-13 Globus Medical, Inc. Device and method for deployment of an anchoring device for intervertebral spinal fusion
US9707100B2 (en) 2015-06-25 2017-07-18 Institute for Musculoskeletal Science and Education, Ltd. Interbody fusion device and system for implantation
EP3111896B1 (en) 2015-06-30 2020-03-04 Werner Consulting AG Prosthetic device
US10016282B2 (en) 2015-07-17 2018-07-10 Globus Medical, Inc. Intervertebral spacer and plate
US10034768B2 (en) 2015-09-02 2018-07-31 Globus Medical, Inc. Implantable systems, devices and related methods
US20180296357A1 (en) * 2015-10-26 2018-10-18 Tobb Ekonomi Ve Teknoloji Universitesi An expandable cage
US10219914B2 (en) 2015-11-10 2019-03-05 Globus Medical, Inc. Stabilized expandable intervertebral spacer
US10369004B2 (en) 2015-12-16 2019-08-06 Globus Medical, Inc. Expandable intervertebralspacer
AU2017202311B2 (en) 2016-04-07 2022-03-03 Howmedica Osteonics Corp. Expandable interbody implant
AU2017203369B2 (en) 2016-05-20 2022-04-28 Howmedica Osteonics Corp. Expandable interbody implant with lordosis correction
US9974662B2 (en) 2016-06-29 2018-05-22 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US10052215B2 (en) 2016-06-29 2018-08-21 Globus Medical, Inc. Expandable fusion device and method of installation thereof
WO2018049227A1 (en) 2016-09-08 2018-03-15 Mayo Foundation For Medical Education And Research Spinal fixation system
EP3292841B8 (en) 2016-09-12 2023-05-31 Howmedica Osteonics Corp. Interbody implant with independent control of expansion at multiple locations
US10307265B2 (en) 2016-10-18 2019-06-04 Institute for Musculoskeletal Science and Education, Ltd. Implant with deployable blades
US10405992B2 (en) 2016-10-25 2019-09-10 Institute for Musculoskeletal Science and Education, Ltd. Spinal fusion implant
AU2017251734B2 (en) * 2016-10-26 2022-10-20 Howmedica Osteonics Corp. Expandable interbody implant with lateral articulation
USD812227S1 (en) 2017-01-25 2018-03-06 Brian D. Burkinshaw Unitary spinal disc implant with a central core
US10441430B2 (en) 2017-07-24 2019-10-15 K2M, Inc. Expandable spinal implants
EP3456294A1 (en) * 2017-09-15 2019-03-20 Stryker European Holdings I, LLC Intervertebral body fusion device expanded with hardening material
USD857200S1 (en) 2018-01-19 2019-08-20 Brian D. Burkinshaw Unitary spinal disc implant
US11259933B2 (en) 2019-09-06 2022-03-01 Globus Medical Inc. Expandable motion preservation spacer
US11191650B2 (en) 2020-02-03 2021-12-07 Globus Medical Inc. Expandable fusions devices, instruments, and methods thereof
US11298240B2 (en) 2020-06-16 2022-04-12 Globus Medical, Inc. Expanding intervertebral implants
US11357640B2 (en) 2020-07-08 2022-06-14 Globus Medical Inc. Expandable interbody fusions devices
US11491020B2 (en) 2020-07-09 2022-11-08 Globus Medical, Inc. Articulating and expandable interbody fusions devices
US11712346B2 (en) 2021-12-02 2023-08-01 Globus Medical, Inc. Expandable fusion device with integrated deployable retention spikes
US11883080B1 (en) 2022-07-13 2024-01-30 Globus Medical, Inc Reverse dynamization implants

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3729600A1 (de) * 1987-09-04 1989-03-16 Aesculap Werke Ag Implantat zum einsetzen zwischen wirbelkoerper der wirbelsaeule
US5236460A (en) * 1990-02-12 1993-08-17 Midas Rex Pneumatic Tools, Inc. Vertebral body prosthesis
US20050049590A1 (en) * 2003-03-07 2005-03-03 Neville Alleyne Spinal implant with securement spikes
US20060142861A1 (en) * 2004-12-29 2006-06-29 Murray Ian P Spinal disc replacement
US20070233254A1 (en) * 2005-09-26 2007-10-04 Thomas Grotz Selectively expanding spine cage, hydraulically controllable in three dimensions for vertebral body replacement

Family Cites Families (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875595A (en) 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
US7452359B1 (en) 1988-06-13 2008-11-18 Warsaw Orthopedic, Inc. Apparatus for inserting spinal implants
US4969888A (en) 1989-02-09 1990-11-13 Arie Scholten Surgical protocol for fixation of osteoporotic bone using inflatable device
US4932975A (en) 1989-10-16 1990-06-12 Vanderbilt University Vertebral prosthesis
US5980522A (en) 1994-07-22 1999-11-09 Koros; Tibor Expandable spinal implants
US5665122A (en) 1995-01-31 1997-09-09 Kambin; Parviz Expandable intervertebral cage and surgical method
FR2730158B1 (fr) 1995-02-06 1999-11-26 Jbs Sa Dispositif de maintien d'un ecartement normal entre les vertebres et destine au remplacement de vertebres manquantes
US5782919A (en) 1995-03-27 1998-07-21 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
DE19519101B4 (de) 1995-05-24 2009-04-23 Harms, Jürgen, Prof. Dr. Höhenverstellbarer Wirbelkörperersatz
US5653763A (en) 1996-03-29 1997-08-05 Fastenetix, L.L.C. Intervertebral space shape conforming cage device
US6835207B2 (en) 1996-07-22 2004-12-28 Fred Zacouto Skeletal implant
FR2753368B1 (fr) 1996-09-13 1999-01-08 Chauvin Jean Luc Cage d'osteosynthese expansive
AU7178698A (en) 1996-11-15 1998-06-03 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US5827328A (en) 1996-11-22 1998-10-27 Buttermann; Glenn R. Intervertebral prosthetic device
US6039761A (en) 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
US6127597A (en) 1997-03-07 2000-10-03 Discotech N.V. Systems for percutaneous bone and spinal stabilization, fixation and repair
US5916267A (en) 1997-04-07 1999-06-29 Arthit Sitiso Anterior spinal implant system for vertebral body prosthesis
JP3955883B2 (ja) 1997-04-15 2007-08-08 ジンテーズ ゲゼルシャフト ミト ベシュレンクテル ハフツング 伸縮式椎体プロテーゼ
FR2762778B1 (fr) 1997-05-02 1999-07-16 Stryker France Sa Implant notamment pour le remplacement d'un corps vertebral en chirurgie du rachis
US5865848A (en) 1997-09-12 1999-02-02 Artifex, Ltd. Dynamic intervertebral spacer and method of use
ES2205159T3 (es) 1997-09-30 2004-05-01 Centerpulse Orthopedics Ltd. Cuerpo de apoyo tubular para puentear dos vertebras.
WO1999066867A1 (fr) 1998-06-23 1999-12-29 Dimso (Distribution Medicale Du Sud-Ouest) Implant intersomatique rachidien a elements d'ancrages
US6193757B1 (en) * 1998-10-29 2001-02-27 Sdgi Holdings, Inc. Expandable intervertebral spacers
US6214012B1 (en) 1998-11-13 2001-04-10 Harrington Arthritis Research Center Method and apparatus for delivering material to a desired location
FR2787018B1 (fr) 1998-12-11 2001-03-02 Dimso Sa Prothese de disque intervertebral a enceinte de liquide
US7070934B2 (en) * 1999-01-12 2006-07-04 Sangamo Biosciences, Inc. Ligand-controlled regulation of endogenous gene expression
US6102950A (en) 1999-01-19 2000-08-15 Vaccaro; Alex Intervertebral body fusion device
US7824445B2 (en) 1999-07-26 2010-11-02 Ladislau Biro Corpectomy vertebral body replacement implant system
WO2002009626A1 (en) 1999-07-26 2002-02-07 Advanced Prosthetic Technologies, Inc. Improved spinal surgical prosthesis
US6454806B1 (en) 1999-07-26 2002-09-24 Advanced Prosthetic Technologies, Inc. Spinal surgical prosthesis
US7177690B2 (en) 1999-07-27 2007-02-13 Advanced Bionics Corporation Implantable system having rechargeable battery indicator
WO2009033100A1 (en) 2007-09-07 2009-03-12 Intrinsic Therapeutics, Inc. Bone anchoring systems
WO2001013807A2 (en) 1999-08-26 2001-03-01 Sdgi Holdings, Inc. Devices and methods for implanting fusion cages
US6866682B1 (en) 1999-09-02 2005-03-15 Stryker Spine Distractable corpectomy device
US6875235B2 (en) 1999-10-08 2005-04-05 Bret A. Ferree Prosthetic joints with contained compressible resilient members
US7060100B2 (en) 1999-10-08 2006-06-13 Ferree Bret A Artificial disc and joint replacements with modular cushioning components
FR2799638B1 (fr) 1999-10-14 2002-08-16 Fred Zacouto Fixateur et articulation vertebrale
WO2001028469A2 (en) 1999-10-21 2001-04-26 Sdgi Holdings, Inc. Devices and techniques for a posterior lateral disc space approach
US6830570B1 (en) 1999-10-21 2004-12-14 Sdgi Holdings, Inc. Devices and techniques for a posterior lateral disc space approach
US6764491B2 (en) 1999-10-21 2004-07-20 Sdgi Holdings, Inc. Devices and techniques for a posterior lateral disc space approach
JP4294901B2 (ja) 1999-12-01 2009-07-15 グラフ，アンリ 椎間安定装置
US6296665B1 (en) 2000-03-20 2001-10-02 Electro-Biology, Inc. Method and apparatus for spinal fixation
AR027685A1 (es) 2000-03-22 2003-04-09 Synthes Ag Forma de tejido y metodo para realizarlo
US6585699B2 (en) 2000-04-13 2003-07-01 Nna/S Drug delivery device provided with a one-way mechanism
US6821298B1 (en) 2000-04-18 2004-11-23 Roger P. Jackson Anterior expandable spinal fusion cage system
US7018416B2 (en) 2000-07-06 2006-03-28 Zimmer Spine, Inc. Bone implants and methods
US20020026244A1 (en) 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US6582467B1 (en) 2000-10-31 2003-06-24 Vertelink Corporation Expandable fusion cage
NL1018438C1 (nl) 2001-07-02 2003-01-08 Baat Medical Engineering B V In- en uitklapbaar gereedschap voor plaatsing in een ruggenwervel.
US6375682B1 (en) 2001-08-06 2002-04-23 Lewis W. Fleischmann Collapsible, rotatable and expandable spinal hydraulic prosthetic device
TW545211U (en) 2001-08-29 2003-08-01 Jung-Chiuan Ye Device for fastening spine
US6648917B2 (en) 2001-10-17 2003-11-18 Medicinelodge, Inc. Adjustable bone fusion implant and method
JP4315816B2 (ja) 2002-04-25 2009-08-19 ブラックストーン メディカル，インコーポレーテッド 人工椎間板
WO2003092507A2 (en) 2002-05-06 2003-11-13 Sdgi Holdings, Inc. Instrumentation and methods for preparation of an intervertebral space
US7060037B2 (en) 2002-05-08 2006-06-13 Medport, Llc Digital thermometer for measuring body temperature
US7066958B2 (en) 2002-05-10 2006-06-27 Ferree Bret A Prosthetic components with partially contained compressible resilient members
US8388684B2 (en) 2002-05-23 2013-03-05 Pioneer Signal Technology, Inc. Artificial disc device
JP4256345B2 (ja) 2002-08-15 2009-04-22 コップス，ジャスティン，ケー． 椎間板インプラント
EP1542626B1 (en) 2002-08-15 2012-09-26 Synthes GmbH Controlled artificial intervertebral disc implant
WO2004016250A1 (en) 2002-08-19 2004-02-26 Orchid Health Care Sustained release pharmaceutical composition of a cephalosporin antibiotic
US7018415B1 (en) 2002-09-23 2006-03-28 Sdgi Holdings, Inc. Expandable spinal fusion device and methods of promoting spinal fusion
WO2004037067A2 (en) 2002-10-21 2004-05-06 3Hbfm, Llc Intervertebral disk prosthesis
AR037168A1 (es) 2002-10-30 2004-10-27 Carrasco Mauricio Rodolfo Implante para reemplazo vertebral y reestablecimiento de la normal curvatura espinal.
US6723126B1 (en) 2002-11-01 2004-04-20 Sdgi Holdings, Inc. Laterally expandable cage
DE10253170A1 (de) 2002-11-14 2004-06-03 Sepitec Foundation Druckfester Hohlkörper zum Einsatz bei Versteifungsoperationen an der Wirbelsäule
US7485143B2 (en) 2002-11-15 2009-02-03 Abbott Cardiovascular Systems Inc. Apparatuses and methods for heart valve repair
US7660623B2 (en) 2003-01-30 2010-02-09 Medtronic Navigation, Inc. Six degree of freedom alignment display for medical procedures
US7828849B2 (en) 2003-02-03 2010-11-09 Warsaw Orthopedic, Inc. Expanding interbody implant and articulating inserter and method
FR2850563B1 (fr) 2003-02-05 2005-11-04 Scient X Implant de remplacement vertebral et appareil de distraction pour la mise en place de l'implant
US7094257B2 (en) 2003-02-14 2006-08-22 Zimmer Spine, Inc. Expandable intervertebral implant cage
US7325021B2 (en) * 2003-03-14 2008-01-29 Nxp B.V. VLSI implementation of metastability-based random number generator using delay ladders
US7824444B2 (en) 2003-03-20 2010-11-02 Spineco, Inc. Expandable spherical spinal implant
EP1610740A4 (en) 2003-04-04 2009-04-08 Theken Disc Llc ARTIFICIAL DISC PROSTHESIS
JP4291779B2 (ja) 2003-04-11 2009-07-08 ジンテーズ ゲゼルシャフト ミト ベシュレンクテル ハフツング 椎間インプラント用の固定手段
US20090005874A1 (en) 2003-04-22 2009-01-01 Fleischmann Lewis W Compressible, rotatable, and tiltable hydraulic spinal disc prosthesis system with selectable modular components
US7419505B2 (en) 2003-04-22 2008-09-02 Fleischmann Lewis W Collapsible, rotatable, and tiltable hydraulic spinal disc prosthesis system with selectable modular components
US6981989B1 (en) 2003-04-22 2006-01-03 X-Pantu-Flex Drd Limited Liability Company Rotatable and reversibly expandable spinal hydraulic prosthetic device
US7407513B2 (en) 2003-05-02 2008-08-05 Smart Disc, Inc. Artificial spinal disk
US7621956B2 (en) 2003-07-31 2009-11-24 Globus Medical, Inc. Prosthetic spinal disc replacement
US7153325B2 (en) 2003-08-01 2006-12-26 Ultra-Kinetics, Inc. Prosthetic intervertebral disc and methods for using the same
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
US7316714B2 (en) 2003-08-05 2008-01-08 Flexuspine, Inc. Artificial functional spinal unit assemblies
US7204853B2 (en) 2003-08-05 2007-04-17 Flexuspine, Inc. Artificial functional spinal unit assemblies
WO2005013852A2 (en) 2003-08-07 2005-02-17 Dynamic Spine, Inc. Intervertebral prosthetic device and associated devices and methods for implanting the intervertebral prosthetic device
WO2005034864A2 (en) 2003-10-08 2005-04-21 University Of North Carolina At Chapel Hill Spine replacement system
US7819922B2 (en) 2003-10-16 2010-10-26 Spinal Generations, Llc Vertebral prosthesis
US7217293B2 (en) 2003-11-21 2007-05-15 Warsaw Orthopedic, Inc. Expandable spinal implant
EP1701657A4 (en) 2004-01-09 2011-08-24 Kent D Yundt METHOD, SYSTEM AND DEVICE FOR THE FUSION OF BODIES
US7485145B2 (en) 2004-02-23 2009-02-03 Alphatec Spine, Incorporated Artificial intervertebral disc assembly
US20050229433A1 (en) 2004-03-03 2005-10-20 Cachia Victor V Catheter deliverable foot implant and method of delivering the same
US7507241B2 (en) 2004-04-05 2009-03-24 Expanding Orthopedics Inc. Expandable bone device
US20050256576A1 (en) 2004-05-13 2005-11-17 Moskowitz Nathan C Artificial expansile total lumbar and thoracic discs for posterior placement without supplemental instrumentation and its adaptation for anterior placement of artificial cervical, thoracic and lumbar discs
US7854766B2 (en) 2004-05-13 2010-12-21 Moskowitz Nathan C Artificial total lumbar disc for unilateral safe and simple posterior placement in the lumbar spine, and removable bifunctional screw which drives vertical sliding expansile plate expansion, and interplate widening, and angled traction spikes
US7794499B2 (en) 2004-06-08 2010-09-14 Theken Disc, L.L.C. Prosthetic intervertebral spinal disc with integral microprocessor
US7470273B2 (en) 2004-06-25 2008-12-30 Ebi, Llc Tool for intervertebral implant manipulation
US7351261B2 (en) 2004-06-30 2008-04-01 Depuy Spine, Inc. Multi-joint implant
US20060036259A1 (en) 2004-08-03 2006-02-16 Carl Allen L Spine treatment devices and methods
US7883543B2 (en) 2004-10-01 2011-02-08 Spinal Generations, Llc Vertebral prosthesis and spinal fixation system
US20060085073A1 (en) 2004-10-18 2006-04-20 Kamshad Raiszadeh Medical device systems for the spine
US8025680B2 (en) 2004-10-20 2011-09-27 Exactech, Inc. Systems and methods for posterior dynamic stabilization of the spine
US20060089719A1 (en) 2004-10-21 2006-04-27 Trieu Hai H In situ formation of intervertebral disc implants
US7594888B2 (en) 2004-10-29 2009-09-29 Depuy Spine, Inc. Expandable ports and methods for minimally invasive surgery
US7291158B2 (en) 2004-11-12 2007-11-06 Boston Scientific Scimed, Inc. Cutting balloon catheter having a segmented blade
US20060167547A1 (en) 2005-01-21 2006-07-27 Loubert Suddaby Expandable intervertebral fusion implants having hinged sidewalls
US9034041B2 (en) 2005-03-31 2015-05-19 Life Spine, Inc. Expandable spinal interbody and intravertebral body devices
US7575580B2 (en) 2005-04-15 2009-08-18 Warsaw Orthopedic, Inc. Instruments, implants and methods for positioning implants into a spinal disc space
EP1903949A2 (en) 2005-07-14 2008-04-02 Stout Medical Group, L.P. Expandable support device and method of use
US8222180B2 (en) * 2005-08-01 2012-07-17 Indian Oil Corporation Limited Adsorbent composition for removal of refractory sulphur compounds from refinery streams and process thereof
US7722674B1 (en) 2005-08-12 2010-05-25 Innvotec Surgical Inc. Linearly expanding spine cage for enhanced spinal fusion
WO2007024990A2 (en) 2005-08-23 2007-03-01 Kim Richard C Expandable implant device with interchangeable spacer
US7731753B2 (en) 2005-09-01 2010-06-08 Spinal Kinetics, Inc. Prosthetic intervertebral discs
US7985256B2 (en) 2005-09-26 2011-07-26 Coalign Innovations, Inc. Selectively expanding spine cage, hydraulically controllable in three dimensions for enhanced spinal fusion
US9028550B2 (en) 2005-09-26 2015-05-12 Coalign Innovations, Inc. Selectively expanding spine cage with enhanced bone graft infusion
US8236058B2 (en) 2005-09-27 2012-08-07 Fabian Henry F Spine surgery method and implant
US20070123987A1 (en) * 2005-11-02 2007-05-31 Bernstein Avi J Curvilinear cervical interbody device
US20070179611A1 (en) 2005-12-22 2007-08-02 Dipoto Gene P Methods and devices for replacement of intervertebral discs
US20070270952A1 (en) 2006-04-19 2007-11-22 Spinal Kinetics, Inc. Prosthetic intervertebral discs implantable by minimally invasive surgical techniques
US20070270961A1 (en) 2006-04-25 2007-11-22 Sdgi Holdings, Inc. Spinal implant with deployable and retractable barbs
US7794501B2 (en) 2006-04-27 2010-09-14 Wasaw Orthopedic, Inc. Expandable intervertebral spacers and methods of use
US7914581B2 (en) 2006-04-27 2011-03-29 Warsaw Orthopedic, Inc. Expandable implant, instrument, and method
US8187331B2 (en) 2006-04-27 2012-05-29 Warsaw Orthopedic, Inc. Expandable vertebral implant and methods of use
US7708779B2 (en) 2006-05-01 2010-05-04 Warsaw Orthopedic, Inc. Expandable intervertebral spacers and methods of use
US20070288092A1 (en) 2006-06-01 2007-12-13 Bambakidis Nicholas Expandable intervertebral implant and method
US7862618B2 (en) 2006-07-19 2011-01-04 Warsaw Orthopedic, Inc. Expandable vertebral body implants and methods of use
US7731752B2 (en) 2006-07-21 2010-06-08 Warsaw Orthopedic, Inc. Implant with nested members and methods of use
US20080058931A1 (en) 2006-07-21 2008-03-06 John White Expandable vertebral implant and methods of use
US20080021556A1 (en) 2006-07-21 2008-01-24 Edie Jason A Expandable vertebral implant and methods of use
US20080065082A1 (en) 2006-09-08 2008-03-13 Narissa Chang Steerable rasp/trial inserter
US20080077241A1 (en) 2006-09-22 2008-03-27 Linh Nguyen Removable rasp/trial member insert, kit and method of use
JP4917485B2 (ja) 2006-10-10 2012-04-18 株式会社堀場製作所 応力成分測定方法
US20080177387A1 (en) 2006-11-01 2008-07-24 Warsaw Orthopedic, Inc. Implants and Related Devices for Monitoring Bony Fusion
US8328871B2 (en) 2006-11-09 2012-12-11 Warsaw Orthopedic, Inc. Expanding vertebral body implant
DE602006011762D1 (de) 2006-11-23 2010-03-04 Biedermann Motech Gmbh Expandierbares Zwischenwirbelimplantat
WO2008065450A1 (en) 2006-11-29 2008-06-05 Surgicraft Limited Orthopaedic implants and prostheses
WO2008070863A2 (en) 2006-12-07 2008-06-12 Interventional Spine, Inc. Intervertebral implant
EP2120800A2 (en) 2007-01-05 2009-11-25 University Of Virginia Patent Foundation Expandable intervertebral prosthesis device for posterior implantation and related method thereof
WO2008112607A2 (en) 2007-03-09 2008-09-18 Blue Fury Consulting, Llc Spinal implant
US11298241B2 (en) 2007-03-29 2022-04-12 Life Spine, Inc. Radially expandable spinal interbody device and implantation tool
US8137401B2 (en) 2007-03-30 2012-03-20 Depuy Spine, Inc. Intervertebral device having expandable endplates
US8273124B2 (en) 2007-05-17 2012-09-25 Depuy Spine, Inc. Self-distracting cage
EP1994900A1 (fr) 2007-05-22 2008-11-26 Flexismed SA Implant vertébral inter-épineux
US7967867B2 (en) 2007-05-31 2011-06-28 Spine Wave, Inc. Expandable interbody fusion device
US20100204794A1 (en) 2007-06-06 2010-08-12 Peter Jarzem Prosthetic vertebral body
US8398649B2 (en) 2007-08-06 2013-03-19 Us Spine, Inc. Articulating transforaminal lumbar interbody fusion inserter device and associated method of use
WO2009064787A2 (en) 2007-11-12 2009-05-22 Synthes (U.S.A.) Adjustable height intervertebral implant
US7985231B2 (en) 2007-12-31 2011-07-26 Kyphon Sarl Bone fusion device and methods
WO2009092102A1 (en) 2008-01-17 2009-07-23 Synthes Usa, Llc An expandable intervertebral implant and associated method of manufacturing the same
EP2087857A1 (en) 2008-02-07 2009-08-12 K2M, Inc. Expandable vertebral device with cam lock
US20100145455A1 (en) 2008-12-10 2010-06-10 Innvotec Surgical, Inc. Lockable spinal implant
US8696751B2 (en) 2008-12-10 2014-04-15 Coalign Innovations, Inc. Adjustable distraction cage with linked locking mechanisms
US8992620B2 (en) 2008-12-10 2015-03-31 Coalign Innovations, Inc. Adjustable distraction cage with linked locking mechanisms
US8932355B2 (en) 2008-02-22 2015-01-13 Coalign Innovations, Inc. Spinal implant with expandable fixation
US8267939B2 (en) 2008-02-28 2012-09-18 Stryker Spine Tool for implanting expandable intervertebral implant
US8574300B2 (en) 2008-03-07 2013-11-05 DePuy Synthes Products, LLC Expandable interbody spacer device
US8062368B2 (en) 2008-04-24 2011-11-22 Warsaw Orthopedic, Inc. Expandable vertebral implants and methods of use
US8172902B2 (en) 2008-07-17 2012-05-08 Spinemedica, Llc Spinal interbody spacers
US8617241B2 (en) 2009-03-31 2013-12-31 Imds Corporation Double bundle ACL repair
US8535377B2 (en) 2009-03-31 2013-09-17 Imds Corporation Double bundle ACL repair system
US8153785B2 (en) 2009-04-06 2012-04-10 Cheminpharma LLC Stabilizing ligands for regulation of protein function
EP3025661B1 (en) 2009-04-16 2017-10-11 Howmedica Osteonics Corp. Apparatus for inserting a medical implant
EP2457001B1 (en) 2009-07-22 2017-11-01 Spinex Tec, LLC Coaxial screw gear sleeve mechanism
DE102010047901B4 (de) 2010-10-11 2019-01-10 Heinrich Böhm Implantat für die Wirbelsäule und Betätigungsinstrument
CN103561691A (zh) 2011-03-30 2014-02-05 三位一体整形有限责任公司 铰接的体间融合器及其方法
US8968402B2 (en) 2011-10-18 2015-03-03 Arthrocare Corporation ACL implants, instruments, and methods
US8663329B2 (en) 2012-01-28 2014-03-04 Mark J Ernst Expandable implant for mammalian bony segment stabilization
US9060870B2 (en) 2012-02-05 2015-06-23 Michael J. Milella, Jr. In-situ formed spinal implant
US9090029B2 (en) 2012-02-06 2015-07-28 Warsaw Orthopedic, Inc. Pultrusion process for preparing composites having low percentage of fibers and articles made from same
US9233007B2 (en) 2012-02-13 2016-01-12 Blue Tip Biologics, Llc Expandable self-anchoring interbody cage for orthopedic applications
US9510955B2 (en) 2012-05-18 2016-12-06 Trinity Orthopedics, Llc Articulating interbody cage and methods thereof
US8940052B2 (en) 2012-07-26 2015-01-27 DePuy Synthes Products, LLC Expandable implant
WO2017027873A1 (en) 2015-08-13 2017-02-16 K2M, Inc. Adjustable spinal implant
US9883953B1 (en) 2016-09-21 2018-02-06 Integrity Implants Inc. Stabilized laterovertically-expanding fusion cage systems with tensioner
FR3058044A1 (fr) 2016-10-27 2018-05-04 Ldr Medical Cage intersomatique expansible
FR3058042B1 (fr) 2016-10-27 2021-12-10 Ldr Medical Implant intervertebral expansible

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3729600A1 (de) * 1987-09-04 1989-03-16 Aesculap Werke Ag Implantat zum einsetzen zwischen wirbelkoerper der wirbelsaeule
US5236460A (en) * 1990-02-12 1993-08-17 Midas Rex Pneumatic Tools, Inc. Vertebral body prosthesis
US20050049590A1 (en) * 2003-03-07 2005-03-03 Neville Alleyne Spinal implant with securement spikes
US20060142861A1 (en) * 2004-12-29 2006-06-29 Murray Ian P Spinal disc replacement
US20070233254A1 (en) * 2005-09-26 2007-10-04 Thomas Grotz Selectively expanding spine cage, hydraulically controllable in three dimensions for vertebral body replacement

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107865714A (zh) * 2016-09-22 2018-04-03 劳伯特·S·萨德达比 可扩展椎间融合植入件
CN111432741A (zh) * 2017-09-01 2020-07-17 斯皮诺洛吉克斯公司 脊柱矫正棒植入物制造过程部分
CN111432741B (zh) * 2017-09-01 2023-05-30 斯皮诺洛吉克斯公司 脊柱矫正棒植入物制造过程部分
CN107485470A (zh) * 2017-09-12 2017-12-19 张坤 一种医用骨科颈椎椎间隙动态稳定植入装置
CN112153951A (zh) * 2018-03-06 2020-12-29 Eit 新兴移植技术股份有限公司 具有集成伸展和角度调节机构的椎间笼
CN112153951B (zh) * 2018-03-06 2024-02-20 Eit 新兴移植技术股份有限公司 具有集成伸展和角度调节机构的椎间笼
CN117204990A (zh) * 2023-11-09 2023-12-12 北京爱康宜诚医疗器材有限公司 一种寰枢椎侧块关节融合器

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