CN105622562B - 一种治疗心脑血管疾病的药物组合物 - Google Patents
一种治疗心脑血管疾病的药物组合物 Download PDFInfo
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- CN105622562B CN105622562B CN201610114417.XA CN201610114417A CN105622562B CN 105622562 B CN105622562 B CN 105622562B CN 201610114417 A CN201610114417 A CN 201610114417A CN 105622562 B CN105622562 B CN 105622562B
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- CN
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- pharmaceutical composition
- cerebrovascular disease
- compound
- group
- treating cardiovascular
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
组别 | AST(U/L) |
正常组 | 81.36±6.52 |
模型组 | 253.51±12.51 |
阳性药组 | 193.72±9.69 |
目标化合物组 | 216.52±11.06 |
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610114417.XA CN105622562B (zh) | 2016-03-01 | 2016-03-01 | 一种治疗心脑血管疾病的药物组合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610114417.XA CN105622562B (zh) | 2016-03-01 | 2016-03-01 | 一种治疗心脑血管疾病的药物组合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105622562A CN105622562A (zh) | 2016-06-01 |
CN105622562B true CN105622562B (zh) | 2017-12-29 |
Family
ID=56037946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201610114417.XA Active CN105622562B (zh) | 2016-03-01 | 2016-03-01 | 一种治疗心脑血管疾病的药物组合物 |
Country Status (1)
Country | Link |
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CN (1) | CN105622562B (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101475552A (zh) * | 2009-02-09 | 2009-07-08 | 沈阳药科大学 | 羟基黄酮衍生物及其抗血小板聚集的用途 |
CN102285951A (zh) * | 2011-09-13 | 2011-12-21 | 辽宁亿灵科创生物医药科技有限公司 | 木犀草素衍生物及其预防和治疗心血管疾病的用途 |
CN103408525A (zh) * | 2013-08-13 | 2013-11-27 | 商洛学院 | 一种黄酮类化合物的合成方法及其应用 |
-
2016
- 2016-03-01 CN CN201610114417.XA patent/CN105622562B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101475552A (zh) * | 2009-02-09 | 2009-07-08 | 沈阳药科大学 | 羟基黄酮衍生物及其抗血小板聚集的用途 |
CN102285951A (zh) * | 2011-09-13 | 2011-12-21 | 辽宁亿灵科创生物医药科技有限公司 | 木犀草素衍生物及其预防和治疗心血管疾病的用途 |
CN103408525A (zh) * | 2013-08-13 | 2013-11-27 | 商洛学院 | 一种黄酮类化合物的合成方法及其应用 |
Non-Patent Citations (1)
Title |
---|
Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities;Wen Luo 等;《Bioorganic & Medicinal Chemistry》;20151218;第24卷;672-680 * |
Also Published As
Publication number | Publication date |
---|---|
CN105622562A (zh) | 2016-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Tian Inventor before: Zhang Hongye |
|
CB03 | Change of inventor or designer information | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20171122 Address after: Qinyuan road 523000 Guangdong Songshan Lake City in Dongguan province the Great Wall family building 503 room 4 Applicant after: Zhang Tian Address before: 052160 Yangzi Road, Shijiazhuang economic and Technological Development Zone, Shijiazhuang, Hebei Province, No. 88 Applicant before: Zhang Hongye |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20230717 Address after: No. 9, Hongmei Avenue, Hongmei Town, Dongguan, Guangdong 523000 Patentee after: Dongguan Asia Pharmaceutical Technology Co.,Ltd. Address before: 523000 room 503, building 4, Changcheng family, Qinyuan Road, Songshan Lake, Dongguan City, Guangdong Province Patentee before: Zhang Tian |
|
TR01 | Transfer of patent right |