CN105616804A

CN105616804A - Medicine for treating latent coronary heart disease

Info

Publication number: CN105616804A
Application number: CN201511022439.5A
Authority: CN
Inventors: 杨桂珍
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-30
Filing date: 2015-12-30
Publication date: 2016-06-01

Abstract

The invention discloses a medicine for treating a latent coronary heart disease. The medicine is mainly prepared from the following raw materials in parts by weight: 12 to 18 parts of radix codonopsis, 12 to 18 parts of radix astragali seu hedysari, 12 to 18 parts of radix salviae miltiorrhizae, 8 to 12 parts of radix angelicae sinensis, 8 to 12 parts of rhizoma corydalis, 8 to 12 parts of rhizoma Chuanxiong, 8 to 12 parts of herba eupatorii, 8 to 12 parts of tangerine peel, 8 to 12 parts of rhizoma pinelliae, 10 to 15 parts of herba pogostemonis, 5 to 7 parts of radix et rhizoma rhei, 4 to 6 parts of radix aconiti lateralis praeparata, 10 to 15 parts of rhizoma acori graminei and 15 to 20 parts of radix rehmanniae. According to the medicine for treating the latent coronary heart disease, disclosed by the invention, fourteen natural traditional Chinese medicines are selected and are scientifically matched; a formula is simple; all crude drugs have a synergistic effect to realize the effects of regulating qi and activating blood, and activating meridians to stop pain; the medicine has a rapid effect, can be used for treating both symptoms and root causes and has no toxic side effect; the medicine for treating the latent coronary heart disease has the advantages of simple preparation method, convenience for orally taking and low cost. The effective rate reaches 94 percent or higher than 94 percent.

Description

It is used for the treatment of the medicine of latent coronary heart disease

Technical field

The present invention relates to Chinese medicine, specifically one is used for the treatment of the medicine of conceal type (silent ischemia) coronary heart disease.

Background technology

Coronary heart disease is middle-aged and old common a kind of cardiovascular disordeies, is cardiac damage that is uneven between the coronary blood flow owing to the functional change of coronary artery or organic disease cause and myocardial demand and that cause. The blood vessel coronary artery that the basic lesion of this disease is supply myocardial nutrition material there occurs atherosis, therefore its full name is coronary atherosclerotic heart disease, referred to as coronary heart disease. Mainly show as stenocardia, irregular pulse, heart failure, it is possible to sudden death. Electrocardiogram(ECG, myocardium enzyme mensuration, radionuclide inspection and coronarography can clearly be diagnosed further. Control blood pressure, blood fat, body weight and smoking cessation can effectively prevent generation and the development of coronary heart disease.

The Hazard Factor of coronary heart disease comprise the Hazard Factor that can change and immutable Hazard Factor. Understand and intervene the control that Hazard Factor contribute to coronary heart disease. The Hazard Factor that can change have: hypertension, hyperlipemia (total cholesterol is too high or low density lipoprotein cholesterol is too high, triglyceride level is too high, high density lipoprotein cholesterol too low), overweight/obesity, hyperglycemia/diabetes, bad life style comprises smoking, unreasonable meals (higher fatty acid, hypercholesterolemia, high calorie etc.), lacks physical exertion, excessive consumption of alcohol, and social mentality's factor. Immutable Hazard Factor have: sex, age, family history. In addition, relevant with infection, such as cytomegalovirus, Chlamydia pneumoniae, helicobacter pylori etc. The outbreak of coronary heart disease usually increases with seasonal variation, excited, physical exertion, full food, a large amount of smoking and drink etc. relevant.

Present is main mainly with Western medicine and operative treatment, but side effect is relatively big, and easily recurs, and can not effect a radical cure, patient's economy and physiology are caused certain burden. And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, treatment cycle is long, and curative effect is not remarkable.

Summary of the invention

It is an object of the invention to provide a kind of good effect, the course for the treatment of is short, cost is low, the medicine being used for the treatment of conceal type (silent ischemia) coronary heart disease that has no side effect.

The technical scheme realizing the object of the invention is:

One is used for the treatment of the medicine of conceal type (silent ischemia) coronary heart disease, and the raw material primarily of following weight parts proportioning is made:

Radix Codonopsis 12-18 part, Radix Astragali 12-18 part, Radix Salviae Miltiorrhizae 12-18 part, Radix Angelicae Sinensis 8-12 part, unit is 8-12 part recklessly, Ligusticum wallichii 8-12 part, eupatorium 8-12 part, dried orange peel 8-12 part, tuber of pinellia 8-12 part, Wrinkled Gianthyssop Herb 10-15 part, rheum officinale 5-7 part, monkshood 4-6 part, calamus 10-15 part, dried rhizome of rehmannia 15-20 part.

The above-mentioned medicine being used for the treatment of conceal type (silent ischemia) coronary heart disease, optimum weight part proportioning of each raw material is:

Radix Codonopsis 15 parts, the Radix Astragali 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Angelicae Sinensis 10 parts, 10 parts recklessly, unit, Ligusticum wallichii 10 parts, eupatorium 10 parts, dried orange peel 10 parts, the tuber of pinellia 10 parts, Wrinkled Gianthyssop Herb 12 parts, rheum officinale 6 parts, monkshood 5 parts, calamus 12 parts, 18 parts, the dried rhizome of rehmannia.

Described raw medicinal material is in shop of Chinese medicines and commercially available.

The preparation method of medicine of the present invention is as follows: take each bulk drug by weight ratio, add mixing and it is placed in container, add material quantity weight 10-20 soak by water doubly 4 times again, decoct every time and boil 30-40min, merge decoction liquor, filter and remove residue, it is the medicinal extract of 1.20-1.40 that filtrate concentrates at 55-60 DEG C relative density, add auxiliary material, make corresponding formulation, to obtain final product.

In the present invention, pharmacology, effect of each bulk drug are as follows:

Radix Codonopsis: have invigorating the spleen and replenishing QI, quench the thirst, be good for spleen benefit lung, nourishing blood to promote the production of body fluid. For spleen-lung Qi deficiency, the few burnout of food, cough void is breathed heavily, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, and Tianjin wound is thirsty, and interior heat is quenched one's thirst.

The Radix Astragali: have enhancing body immunologic function, protect liver, diuresis, anti-ageing, anti-stress, step-down and anti-microbial effect more widely. The Radix Astragali can not only coronary artery dilator, improve blood supply of cardiac muscle, it is to increase immunologic function, and can the process of delaying cell aging.

Radix Salviae Miltiorrhizae: the stasis of blood of dispelling, raw new, invigorate blood circulation, the effectiveness such as menstruation regulating, be gynaecology's key medicine, cure mainly uterine hemorrhage, menoxenia, the blood stasis of blood, stomachache, dysmenorrhoea, through closing, mausoleum pain. Treatment coronary heart disease there is good result. In addition also controlling the weak insomnia of nervosa, arthrodynia, anaemia, mazoitis, lymphadenitis, sacroiliitis, sore furuncle pain is swollen, erysipelas, acute, chronic hepatitis, nephropyelitis, wound, and advanced schistosomiasis hepatosplenomegaly is insane.

Radix Angelicae Sinensis: having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect relaxed bowel. Being usually used in the deficiency of blood sallow, dizzy palpitaition, menoxenia, through closing dysmenorrhoea, the cold of insufficiency type is suffered from abdominal pain, rheumatic arthralgia, injury from falling down, ulcer sores, the dry constipation of intestines.

Unit's Hu: have promoting blood circulation to remove blood stasis, the function of profit gas pain relieving. For whole body each portion qi depression to blood stasis pain, dysmenorrhoea, through closing, abdominal mass, postpartum stasis blocking, injury from falling down, hernia is had a pain.

Ligusticum wallichii: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain. Controlling air-cooled headache revolves dizzy, hypochondriac pain abdomen ache, arthritis muscle contraction, through closing, difficult labour, postpartum stasis blocking block pain, ulcer sores. For menoxenia, through closing dysmenorrhoea, lump in the abdomen is suffered from abdominal pain, chest side of body shouting pain, tumbling and swelling, headache, rheumatic arthralgia.

Eupatorium: remove dampness by means of aromatics, appetizing of being amusing, delivers the effect separating heat. For turbid damp obstructing in middle-JIAO, gastral cavity ruffian is vomitted evil, sweet greasy in mouth, halitosis, polysialia, summer-heat and damp illness that has not attacked the vital organs of the human body, and damp-warm syndrome, from the beginning of, heating burnout, uncomfortable in chest is not relaxed. For distension and fullness in the abdomen, food is few vomits and diarrhoea, coughing with a lot of sputum.

The tuber of pinellia: have eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, effect of dissolving lump and resolving mass. For the cold phlegm of wet phlegm, coughing that to breathe heavily phlegm many, phlegm and retained fluid is dizzy throbs with fear, dizziness due to wind-phlegm, and coma due to blocking of the respiratory system is had a headache, vomiting gastric disorder causing nausea, and chest gastral cavity ruffian is vexed, globus hystericus; Control the swollen phlegm core of carbuncle outward.

Wrinkled Gianthyssop Herb: eliminate dampness with aromatics, and termination vomits, and delivers solution heat. For turbid damp obstructing in middle-JIAO, gastral cavity ruffian is vomitted, summer-heat and damp illness that has not attacked the vital organs of the human body, damp-warm syndrome from the beginning of, heating burnout, uncomfortable in chest does not relax, and cold-dampness closes heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.

Rheum officinale: purge heat logical intestines, and removing pattogenic heat from the blood and toxic material from the body, stimulates the menstrual flow by the stasis of blood. For real hot constipation, stagnant stomachache, rushes down dysentery not well, jaundice due to damp-heat, and blood-head tells nosebleed, hot eyes, and pharynx is swollen, abdominalgia with intestinal abscess, and carbuncle swells furunculosis, hemostasis through closing, wound, burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.

Monkshood: recuperating deplered YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain. For yang depletion collapse, the cold arteries and veins of limb is micro-, deficiency of heart-YANG, Obstruction of qi in the chest and cardialgia, and the cold of insufficiency type is vomited and diarrhoea, coldness and pain in the epigastrium, kidney yang deficiency, and impotence palace is cold, cloudy cold oedema, deficiency of yang diseases caused by external factors, arthralgia due to cold-dampnes.

Calamus: reduce phlegm, has one's ideas straightened out, and strong spleen, profit is wet. For epilepsy, palpitating with fear forgetful, clouded in mind, wet stagnant ruffian is swollen, dysentery, rheumatalgia, and carbuncle swells scabies.

The dried rhizome of rehmannia: the effect with clearing heat and cooling blood, benefit Yin and promoting production of body liquid. Entering ying blood for febrile disease heat, strong hot coma, dry tongue is deep red, as sought clearly soup.

The present invention is used for the treatment of the medicine of conceal type (silent ischemia) coronary heart disease, choose 14 kinds of natural traditional Chinese medicine scientific compatibility, formula is simple, the effect that each bulk drug acts synergistically and plays vital energy regualting and blood circulation-promoting, removes obstruction in channels to relieve pain, instant effect, treats both principal and secondary aspect of disease, and has no side effect, and its preparation method is simple, easy administration, cost is low.

Embodiment

Below in conjunction with embodiment, content of the present invention is further described, but it is not limitation of the invention.

Embodiment 1

Radix Codonopsis 12kg, Radix Astragali 12kg, Radix Salviae Miltiorrhizae 12kg, Radix Angelicae Sinensis 8kg, unit is 8kg, Ligusticum wallichii 8kg, eupatorium 8kg, dried orange peel 8kg, tuber of pinellia 8kg, Wrinkled Gianthyssop Herb 10kg, rheum officinale 5kg, monkshood 4kg, calamus 10kg, dried rhizome of rehmannia 15kg recklessly.

Preparation method is as follows: take the mixing of each bulk drug be placed in container by above-mentioned, then add the soak by water 4 times of material quantity weight 10 times, decoct every time and boil 30min, merging decoction liquor, filter and remove residue, it is the medicinal extract of 1.20 that filtrate concentrates at 55 DEG C relative density, add auxiliary material, make tablet, every sheet 0.1g.

Embodiment 2

Radix Codonopsis 15kg, Radix Astragali 15kg, Radix Salviae Miltiorrhizae 15kg, Radix Angelicae Sinensis 10kg, unit is 10kg, Ligusticum wallichii 10kg, eupatorium 10kg, dried orange peel 10kg, tuber of pinellia 10kg, Wrinkled Gianthyssop Herb 12kg, rheum officinale 6kg, monkshood 5kg, calamus 12kg, dried rhizome of rehmannia 18kg recklessly.

Preparation method is as follows: take the mixing of each bulk drug be placed in container by above-mentioned, then add the soak by water 4 times of material quantity weight 15 times, decoct every time and boil 34min, merging decoction liquor, filter and remove residue, it is the medicinal extract of 1.30 that filtrate concentrates at 55 DEG C relative density, add auxiliary material, make tablet, every sheet 0.2g.

Embodiment 3

Radix Codonopsis 18kg, Radix Astragali 18kg, Radix Salviae Miltiorrhizae 18kg, Radix Angelicae Sinensis 12kg, unit is 12kg, Ligusticum wallichii 12kg, eupatorium 12kg, dried orange peel 12kg, tuber of pinellia 12kg, Wrinkled Gianthyssop Herb 15kg, rheum officinale 7kg, monkshood 6kg, calamus 15kg, dried rhizome of rehmannia 20kg recklessly.

Preparation method is as follows: take the mixing of each bulk drug be placed in container by above-mentioned, then add the soak by water 4 times of material quantity weight 18 times, decoct every time and boil 37min, merging decoction liquor, filter and remove residue, it is the medicinal extract of 1.30 that filtrate concentrates at 58 DEG C relative density, add auxiliary material, make pill, every 0.4g.

Embodiment 4

Preparation method is as follows: take the mixing of each bulk drug be placed in container by above-mentioned, then add the soak by water 4 times of material quantity weight 20 times, decoct every time and boil 40min, merging decoction liquor, filter and remove residue, it is the medicinal extract of 1.40 that filtrate concentrates at 60 DEG C relative density, add auxiliary material, make pill, every 0.5g.

In order to prove the clinical efficacy of Chinese medicine of the present invention further, select 200 examples accepted for medical treatment in patient, the curative effect of medicine of the present invention is carried out clinical observation. Age 50-70 year, be divided into 4 groups at random, often group be 50 example, be respectively experimental group 1-4 group.

Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 2 times, for oral administration 5 slices/every time, within 14 days, is a course for the treatment of, takes 1-3 the course for the treatment of continuously. Wherein effective 185 examples, effective 188 examples, cure 180 examples, and invalid 12 examples, curative ratio 90%, has efficiency 94%.

Claims

1. it is used for the treatment of a latent coronary heart disease medicine, it is characterized in that: the raw material primarily of following weight parts proportioning is made:

2. the medicine being used for the treatment of latent coronary heart disease according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:

3. the medicine being used for the treatment of latent coronary heart disease according to claim 1, is characterized in that:

Preparation method is as follows: take each bulk drug by weight ratio, add mixing and it is placed in container, add material quantity weight 10-20 soak by water doubly 4 times again, decoct every time and boil 30-40min, merge decoction liquor, filter and remove residue, it is the medicinal extract of 1.20-1.40 that filtrate concentrates at 55-60 DEG C relative density, add auxiliary material, make corresponding formulation, to obtain final product.