CN105055937A

CN105055937A - Traditional Chinese medicine for treating hyperthyroid cardiopathy

Info

Publication number: CN105055937A
Application number: CN201510450348.5A
Authority: CN
Inventors: 吴斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-07-28
Filing date: 2015-07-28
Publication date: 2015-11-18

Abstract

The invention relates to a traditional Chinese medicine for treating hyperthyroid cardiopathy. The traditional Chinese medicine is prepared by the following raw herbal materials in parts by weight: 20 parts of epimedium gradiflorum morr, 20 parts of tuber fleeceflower stem, 12 parts of melia toosendan, 15 parts of semen lepidii, 10 parts of Chinese polyphaga, 12 parts of earthworm, 12 parts of polyporus umbellatus and 12 parts of wild rice. A clinical experiment proves that the traditional Chinese medicine can treat the hyperthyroid cardiopathy safely and effectively.

Description

A kind of Chinese medicine being used for the treatment of hyperthyroid heart disease

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of hyperthyroid heart disease.

Background technology

Thyrotoxic heart disease refers to when hyperthyroidism, and thyroxine is to a kind of endocrine and metabolic disorders heart disease of a series of cardiovascular symptoms such as cardiac dilatation, atrial fibrillation, myocardial infarction, heart failure, sick sinus syndrome and the cardiomyopathy caused by the direct or indirect effect of heart and sign.Being only second to hyperthyroidism crisis to patients ' lives and healthy impact, is one of major reason of Patients with Hyperthyroidism death.Hyperthyroid heart disease belongs to more in Chinese medicine " cardiopalmus ", " palpitation with a distress feeling ", the category such as " thoracic obstruction, pained ".Hyperthyroid heart disease mostly occurred in the hyperthyroidism later stage, and older, therefore based on deficiency in origin, occurred the pathological change of simulataneous insufficiency and excessive, namely on the basis that internal organs are deficient, and the various pathological products of visible " excess caused by deficiency ".Basic pathogenesis is deficiency of heart-QI, hyperactivity of YANG due to deficiency of YIN, and mental disorder is condensed, and blood-vessel obstructive is in close relations with Liver and kidney.Contain as this with deficiency of heart-QI, hyperactivity of YANG due to deficiency of YIN, expectorant is turbid, stagnation of blood stasis is mark, deficiency in origin and excess in superficiality.Conscience the moon wound, the heart is become homeless foster, then palpitation and being susceptible to fright; Heart kidney yin is lost, then the high Sheng of heart-yang, and heartbeat is accelerated.Be the main rule for the treatment of with supplementing QI and nourishing YIN, heat clearing away mind calming, tranquillizing the mind by relieving convulsion.

Medical material present Research involved in the present invention is as follows:

Herba Epimedii [another name] Epimedium, Herba Epimedii, Birdfoot, trident wind, epilepsy, Herba Epimedii, three furculas, Herba Saniculae lamelligerae, Rhizoma Smilacis Chinensis.[source] this product is the dry aerial parts of Berberidaceae plant Herba Epimedii, Epimedium sagittatum, E. Pubescens, Epimedium wushanense or Herba Epimedii.Tap when summer, autumn, stem and leaf was luxuriant, the thick stalk of removing and impurity, dry or dry in the shade.[nature and flavor] acrid, sweet, warm.[return through] returns liver, kidney channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] empty YANG transmission is lifted, and nocturnal emission is more than, just red xerostomia, strong sun not flaccidity avoid it.[extracts] " China's book on Chinese herbal medicine ".

Caulis Polygoni Multiflori [another name] Caulis Polygoni Multiflori.[source] this product is the dry rattan of polygonum multiflorum thunb.Autumn, season in winter two tap, and remove residual leaf, are bundled into handle, dry.[nature and flavor] are sweet, flat.[return through] GUIXIN, Liver Channel.[function cures mainly] nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.For insomnia and dreamful sleep, blood deficiency general pain, rheumatic arthralgia; External treatment skin pruritus.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".

Fructus Toosendan [another name] Fructus Toosendan, Fructus Toosendan are real.[source] this product is the dry mature fruit of Meliaceae plant Fructus Toosendan.Gather during fruit maturation in winter, removing impurity, dry.[nature and flavor] are bitter, cold.[return through] returns liver, small intestinal, urinary bladder channel.[function cures mainly] soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] Deficiency and coldness of spleen and stomach person avoids clothes.Fructus Foeniculi makes .[take passages for it] " China's book on Chinese herbal medicine ".

Suitable greatly, the large room of Semen Lepidii (Semen Descurainiae) [another name], Dian Artemisia, Ding Li.[source] this product is the dry mature seed of crucifer Lepidium sativum L. or descurainia sophia (l.) webb ex prantl.The former practises title " lepidii,semen ", and the latter practises title " Semen Descurainiae ".Tap plant during fruit maturation in summer, dry, rub seed, removing impurity.[nature and flavor] are pungent, bitter, Great Cold.[return through] returns lung, urinary bladder channel.[function cures mainly] eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] deficiency of the lung is breathed with cough, insufficiency of the spleen generalized edema with distention of the chest and abdomen person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".

Eupolyphaga Seu Steleophaga [another name] Eupolyphaga Seu Steleophaga, eupolyphaga, DIWUGUI, female ground beetle.[source] this product is the female worm dry body of Corydiidae insecticide eupolyphoge sinensis or Ji eupolyphoge sinensis.After seizure, put in boiling water and scald extremely, dry or dry.[nature and flavor] are salty, cold; [return through] returns Liver Channel.[function cures mainly] removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is forbidden.[extracts] " China's book on Chinese herbal medicine ".

Pheretima [another name] Lumbricus, cricket earthworm, bent worm, native Dan, red worm.[source] this product is the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or the blind Pheretimatschiliensis of comb.Front one is practised and is claimed " LUMBRICUS ", practises title " Shanghai Pheretima " for latter three kinds.LUMBRICUS catches to autumn spring, and Shanghai Pheretima catches summer, cuts abdominal part open in time, and removing internal organs and silt are cleaned, dried or cold drying.[nature and flavor] are salty, cold.[return through] returns liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.[usage and dosage] takes orally: decoct soup, 4.5-9g.[attention] Deficiency and coldness of spleen and stomach should not take, and anemia of pregnant woman prohibits clothes.[extracts] " China's book on Chinese herbal medicine ".

Polyporus [another name] pig Ling, Jia pig dung, pig Tuo, pig Siberian cocklebur, Rhizoma Anemones flaccidae Fructus Persicae, wild boar food, polyporus umbellatus.[source] is the dry sclerotia of Polyporaceae plant Polyporus.South is all adopted the whole year, and the north is many with summer, season in autumn two.Remove silt particle after digging out, dry.Put dry ventilation.[nature and flavor] are sweet light, flat.[return through] enters spleen, kidney, urinary bladder channel.[function cures mainly] diuresis eliminating dampness by diuresis.Control dysuria, edema distension, beriberi, has loose bowels, drench, turbid, leukorrhagia.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] Polyporus is light oozes, and large dry depletion of body fluid, does not take without damp syndrome.[extracts] " China's book on Chinese herbal medicine ".

Fructus Zizaniae caduciflorae [another name] wild goose meals, wild rice fine strain of millet, peace Hu, Jiang Shi, hay rice, fructus zizaniae caduciflorae, carving Hu rice, carving wild rice, zizaniae,fructus, wild rice are in fact.[source] is the fruit of grass wild rice Vulpes.Gather and store: the 9-10 month, taking after fruit maturation, rubbing with the hands and remove crust, Yang Jing, dry.[nature and flavor] sweet in the mouth; Cold in nature.[return through] returns large intestine, stomach warp.[function cures mainly] controls heart disease etc., or makes diuretic.Relieving restlessness is quenched the thirst; Stomach function regulating reason intestinal.Main vexed; Thirsty; Constipation; Dysuria; Infantile diarrhea.For headache due to pathogenic wind-heat, measles is not smooth, toothache aphtha, laryngopharynx swelling and pain, visceroptosis.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] yang deficiency sun is floating, and dyspnea with fullness of the chest QI rising in reverse order and measles thoroughly person avoid use.Elevate a turnable ladder yang-energy should with processing Fructus Zizaniae caduciflorae.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of hyperthyroid heart disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing hyperthyroid heart disease.

In order to achieve the above object, the present invention is by the following technical solutions:

A kind of Chinese medicine being used for the treatment of hyperthyroid heart disease, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Epimedii 20 parts, Caulis Polygoni Multiflori 20 parts, Fructus Toosendan 12 parts, Semen Lepidii (Semen Descurainiae) 15 parts, Eupolyphaga Seu Steleophaga 10 parts, Pheretima 12 parts, Polyporus 12 parts, Fructus Zizaniae caduciflorae 12 parts.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and hyperthyroid heart disease patient 64 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 34 example and matched group 30 example at random, treatment group man 13 example, female 21 example, 24 ~ 75 years old age, 45.4 years old mean age, the hyperthyroidism course of disease 1 ~ 25 year; Matched group man 12 example, female 18 example, 25 ~ 73 years old age, 44.7 years old mean age, the hyperthyroidism course of disease 6 ~ 24 years.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national hyperthyroid heart disease clinical speciality: (1) makes a definite diagnosis hyperthyroidism; (2) paroxysmal or permanent atrial fibrillation, atrial flutter, cardiac enlargement or heart failure person; (3) heart disease of other reason is got rid of; (4) after hyperthyroidism healing, cardiac symptom disappears thereupon.

2, test method

2.1 Therapeutic Method

The oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 3, and the course for the treatment of is 4 weeks, 4 ~ 6 courses for the treatment of of Continuous Observation.

The oral propylthiouracil 200-300mg/d of matched group, with to 1 month, treats that symptom controls, after first merit is normal, and progressively decrement, maintenance dose.The course for the treatment of is 4 weeks, 4 ~ 6 courses for the treatment of of Continuous Observation.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Clinic control: transference cure, heart rate is normal, and thyroid function and electrocardiogram all recover normal, follows up a case by regular visits in 1 year without recurrence;

Effective: clinical symptoms is obviously improved, heart rate obviously slows down, thyroid function and Electrocardioscopy normal, but had in 1 year recurrence or the western medicines such as thiamazole need be assisted simultaneously;

Invalid: not reach improvement standard or do not adhere to medication therapist.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Visible, the medicine that the present invention obtains can safe and effective treatment hyperthyroid heart disease, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Herba Epimedii 20 grams, Caulis Polygoni Multiflori 20 grams, Fructus Toosendan 12 grams, Semen Lepidii (Semen Descurainiae) 15 grams, Eupolyphaga Seu Steleophaga 10 grams, Pheretima 12 grams, Polyporus 12 grams, Fructus Zizaniae caduciflorae 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of hyperthyroid heart disease.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 2

Take: Herba Epimedii 20 grams, Caulis Polygoni Multiflori 20 grams, Fructus Toosendan 12 grams, Semen Lepidii (Semen Descurainiae) 15 grams, Eupolyphaga Seu Steleophaga 10 grams, Pheretima 12 grams, Polyporus 12 grams, Fructus Zizaniae caduciflorae 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Embodiment 3

Take: Herba Epimedii 20 grams, Caulis Polygoni Multiflori 20 grams, Fructus Toosendan 12 grams, Semen Lepidii (Semen Descurainiae) 15 grams, Eupolyphaga Seu Steleophaga 10 grams, Pheretima 12 grams, Polyporus 12 grams, Fructus Zizaniae caduciflorae 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Claims

1. one kind is used for the treatment of the Chinese medicine of hyperthyroid heart disease, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Epimedii 20 parts, Caulis Polygoni Multiflori 20 parts, Fructus Toosendan 12 parts, Semen Lepidii (Semen Descurainiae) 15 parts, Eupolyphaga Seu Steleophaga 10 parts, Pheretima 12 parts, Polyporus 12 parts, Fructus Zizaniae caduciflorae 12 parts.