CN106075317A - For treating the medicine of coronary heart disease - Google Patents

For treating the medicine of coronary heart disease Download PDF

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CN106075317A
CN106075317A CN201610704359.6A CN201610704359A CN106075317A CN 106075317 A CN106075317 A CN 106075317A CN 201610704359 A CN201610704359 A CN 201610704359A CN 106075317 A CN106075317 A CN 106075317A
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rhizoma
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heart disease
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黄琴
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    • A61K36/88Liliopsida (monocotyledons)
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Abstract

The invention discloses a kind of medicine for treating coronary heart disease, be mainly made up of the raw material of following weight parts proportioning: Bulbus Allii Macrostemonis 10 15 parts, Pericarpium Citri 57 parts, Rhizoma Chuanxiong 8 12 parts, Radix Ophiopogonis 8 12 parts, the Radix Paeoniae Alba 8 12 parts, 8 12 parts of Flos Carthami, RADIX CURCUMAE 8 12 parts, Rhizoma Corydalis 8 10 parts, 8 12 parts of Poria, Radix Salviae Miltiorrhizae 8 10 parts, Radix Notoginseng 57 parts, Rhizoma Polygonati Odorati 6 10 parts, Fructus Schisandrae Chinensis 8 10 parts, Rhizoma Curcumae 8 12 parts, Fructus Trichosanthis 57 parts, Rhizoma Acori Graminei 57 parts.The present invention, for treating the medicine of coronary heart disease, chooses 15 kinds of natural Chinese medicine scientific compatibility, and formula is simple, each crude drug synergism plays the effect of vital energy regualting and blood circulation-promoting, removing obstruction in the collateral to relieve pain, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, low cost.Effective percentage reaches more than 94.7%.

Description

For treating the medicine of coronary heart disease
Technical field
The present invention relates to Chinese medicine, a kind of medicine for treating coronary heart disease.
Background technology
Coronary heart disease is a kind of cardiovascular disease that middle-aged and elderly people is common, is due to coronary artery functional change or organic Uneven and the cardiac damage that causes between coronary blood flow and myocardial demand that pathological changes causes.The basic lesion of primary disease is the supply heart The blood vessel coronary artery of myotrophy material there occurs atherosis, therefore its full name is coronary atherosclerotic heart Disease, referred to as coronary heart disease.Mainly show as angina pectoris, arrhythmia, heart failure, may sudden death.Electrocardiogram, myocardium enzyme are surveyed Calmly, radio nuclide examination and coronarography can be clarified a diagnosis further.Control blood pressure, blood fat, body weight and smoking cessation can have Effect prevents generation and the development of coronary heart disease.
The risk factor of coronary heart disease includes changeable risk factor and unmodifiable risk factor.Understand and intervene danger Danger factor contributes to the preventing and treating of coronary heart disease.Changeable risk factor has: hypertension, and (T-CHOL is the most high or low for dyslipidemia Density lipoprotein-cholesterol is too high, triglyceride is too high, HDL-C too low), overweight/obesity, hyperglycemia/sugar Urine disease, bad life style include smoking, unreasonable meals (higher fatty acid, hypercholesterolemia, high heat etc.), lack physical exertion, Excessive consumption of alcohol, and socio-psychological factors.Unmodifiable risk factor has: sex, age, family history.Additionally, have with infection Close, such as cytomegalovirus, Chlamydia pneumoniae, helicobacter pylori etc..The outbreak of coronary heart disease usually with seasonal variations, excited, Physical exertion increases, is satiated with food, a large amount of smoking and drink etc. relevant.
The most based on Western medicine and operative treatment, but side effect is relatively big, and easily recur, it is impossible to radical cure, to patient Economy and physiology cause certain burden.And the therapeutic efficiency of some current Chinese medicines is the most not satisfactory, treatment cycle is long, and treats Imitate the most notable.
Summary of the invention
It is an object of the invention to provide a kind of good effect, short treating period, low cost, have no side effect for treating coronary heart disease Medicine.
The technical scheme realizing the object of the invention is:
A kind of medicine for treating coronary heart disease, is mainly made up of the raw material of following weight parts proportioning:
Bulbus Allii Macrostemonis 10-15 part, Pericarpium Citri 5-7 part, Rhizoma Chuanxiong 8-12 part, Radix Ophiopogonis 8-12 part, Radix Paeoniae Alba 8-12 part, Flos Carthami 8-12 part, RADIX CURCUMAE 8-12 part, Rhizoma Corydalis 8-10 part, Poria 8-12 part, Radix Salviae Miltiorrhizae 8-10 part, Radix Notoginseng 5-7 part, Rhizoma Polygonati Odorati 6-10 part, Fructus Schisandrae Chinensis 8-10 Part, Rhizoma Curcumae 8-12 part, Fructus Trichosanthis 5-7 part, Rhizoma Acori Graminei 5-7 part.
The above-mentioned medicine for treating coronary heart disease, optimum weight part proportioning of each raw material is:
Bulbus Allii Macrostemonis 12 parts, Pericarpium Citri 6 parts, Rhizoma Chuanxiong 10 parts, Radix Ophiopogonis 10 parts, the Radix Paeoniae Alba 10 parts, 10 parts of Flos Carthami, RADIX CURCUMAE 10 parts, unit 9 parts recklessly, 10 parts of Poria, Radix Salviae Miltiorrhizae 9 parts, Radix Notoginseng 6 parts, Rhizoma Polygonati Odorati 8 parts, Fructus Schisandrae Chinensis 9 parts, Rhizoma Curcumae 10 parts, Fructus Trichosanthis 6 parts, Rhizoma Acori Graminei 6 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, after adding alcohol dipping 5-7 days that 4-6 times of concentration of material quantity is 40-60%, filter and remove residue, decompression filtrate recycling ethanol is extremely Taste without alcohol, obtains concentrated solution 60-100 part, standby;
(2) in the concentrated solution that step (1) prepares, add 800-1000 part water and 0.8-1 part potassium sorbate, stir evenly, stand 20-30h, filters, obtains filtrate, standby;
(3) separately with 60-100 part sucrose, add 100-150 part water boil 30-40min, filter, standby;
(4) the filtrate mixing of step (2) and (3) is placed in container, adds 800-1000 part water, bottle after cooling, seal After carry out sterilization treatment, make product.
In the present invention, the pharmacology of each crude drug, effect are as follows:
Bulbus Allii Macrostemonis: activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen feeling of fullness distending pain, weight after dysentery.
Pericarpium Citri: liver-smoothing, qi-regulating, alleviating distention in middle-JIAO, reduces phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavity abdomen feeling of fullness, vomit eructation, expectorant Many coughs.
Rhizoma Chuanxiong: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache rotation dizzy, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, warp Close, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass suffers from abdominal pain, breast side of body twinge, tumbling and swelling, Headache, rheumatic arthralgia.
Radix Ophiopogonis: Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, clear away heart-fire relieving restlessness, cure mainly Radix Ophiopogonis consumption of body fluid caused by febrile disease, vexed, thirsty, dry pharynx lung-heat, Cough, pulmonary tuberculosis.
The Radix Paeoniae Alba: there is nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, effect of suppressing liver-YANG.It is usually used in blood deficiency and yellow complexion, the moon Through uncomfortable, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, dizziness of having a headache.
Flos Carthami: there is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, the thoracic obstruction Pained, the stagnant stomachache of the stasis of blood, breast side of body twinge, injury from falling down, skin infection swells and ache.
RADIX CURCUMAE: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, promoting the function of the gallbladder to alleviate jaundice.
Rhizoma Corydalis: have promoting blood circulation to remove blood stasis, the function of regulating QI to relieve pain.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, disease Abdominal mass, postpartum stagnation, injury from falling down, hernia is had a pain.
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, the mind Uneasiness, palpitation with fear insomnia.
Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen Hypochondriac pain, the accumulation of abdominal mass abdominal mass, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache.
Radix Notoginseng: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen sting Bitterly, tumbling and swelling.
Rhizoma Polygonati Odorati: there is nourishing YIN to relieve dryness, effect of promoting the production of body fluid to quench thirst.It is usually used in lung stomach-Yin to hinder, cough caused by dryness-heat, dry throat and mouth, interior Heat is quenched one's thirst.
Fructus Schisandrae Chinensis: there is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming.It is usually used in chronic cough dyspnea due to deficiency, emission, Enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.
Rhizoma Curcumae: curing mainly coagulation of QI-blood, trusted subordinate's distending pain, lump in the abdomen, accumulation, dyspepsia does not disappears, women's blood stasis amenorrhea, and traumatic injury is made Bitterly.There are promoting QI circulation for relieving depression, removing blood stasis with potent drugs, the function of pain relieving.
Fructus Trichosanthis: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest painful abdominal mass Full, acute mastitis, lung abscess, acute appendicitis swells and ache, constipation.
Rhizoma Acori Graminei: reduce phlegm, has one's ideas straightened out, spleen invigorating, dampness removing.For epilepsy, palpitating with fear forgetful, obnubilation, humidity hysteresis painful abdominal mass is swollen, dysentery of having loose bowels Disease, rheumatalgia, carbuncle scabies.
The present invention, for treating the medicine of coronary heart disease, chooses 15 kinds of natural Chinese medicine scientific compatibility, and formula is simple, each crude drug Synergism plays the effect of vital energy regualting and blood circulation-promoting, removing obstruction in the collateral to relieve pain, instant effect, treating both the principal and secondary aspects of a disease, has no side effect, and its preparation method Simply, taking convenience, low cost.
Detailed description of the invention
Below in conjunction with embodiment, present invention is further described, but is not limitation of the invention.
Embodiment 1
A kind of medicine for treating coronary heart disease, is mainly made up of the raw material of following weight parts proportioning:
Bulbus Allii Macrostemonis 10kg, Pericarpium Citri 5kg, Rhizoma Chuanxiong 8kg, Radix Ophiopogonis 8kg, Radix Paeoniae Alba 8kg, Flos Carthami 8kg, RADIX CURCUMAE 8kg, Rhizoma Corydalis 8kg, Poria 8kg, Radix Salviae Miltiorrhizae 8kg, Radix Notoginseng 5kg, Rhizoma Polygonati Odorati 6kg, Fructus Schisandrae Chinensis 8kg, Rhizoma Curcumae 8kg, Fructus Trichosanthis 5kg, Rhizoma Acori Graminei 5kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 4 times of concentration of material quantity is the alcohol dipping of 40% after 5 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 60kg, standby;
(2) in the concentrated solution that step (1) prepares, add 800kg water and 0.8kg potassium sorbate, stir evenly, stand 20h, mistake Filter, obtains filtrate, standby;
(3) separately use 60kg sucrose, add 100kg water boil 30min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add 800kg water, bottle after cooling, seal after carry out Sterilization treatment, makes product.
Embodiment 2
A kind of medicine for treating coronary heart disease, is mainly made up of the raw material of following weight parts proportioning:
Bulbus Allii Macrostemonis 12kg, Pericarpium Citri 6kg, Rhizoma Chuanxiong 10kg, Radix Ophiopogonis, 10kg, Radix Paeoniae Alba 10kg, Flos Carthami 10kg, RADIX CURCUMAE 10kg, first 9kg recklessly, Poria 10kg, Radix Salviae Miltiorrhizae 9kg, Radix Notoginseng 6kg, Rhizoma Polygonati Odorati 8kg, Fructus Schisandrae Chinensis 9kg, Rhizoma Curcumae 10kg, Fructus Trichosanthis 6kg, Rhizoma Acori Graminei 6kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 5 times of concentration of material quantity is the alcohol dipping of 50% after 6 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 80kg, standby;
(2) in the concentrated solution that step (1) prepares, add 900kg water and 0.89kg potassium sorbate, stir evenly, stand 25h, mistake Filter, obtains filtrate, standby;
(3) separately use 80kg sucrose, add 125kg water boil 35min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add 900kg water, bottle after cooling, seal after carry out Sterilization treatment, makes product.
Embodiment 3
A kind of medicine for treating coronary heart disease, is mainly made up of the raw material of following weight parts proportioning:
Bulbus Allii Macrostemonis 15kg, Pericarpium Citri 7kg, Rhizoma Chuanxiong 12kg, Radix Ophiopogonis, 12kg, Radix Paeoniae Alba 12kg, Flos Carthami 12kg, RADIX CURCUMAE 12kg, first 10kg recklessly, Poria 12kg, Radix Salviae Miltiorrhizae 10kg, Radix Notoginseng 7kg, Rhizoma Polygonati Odorati 10kg, Fructus Schisandrae Chinensis 10kg, Rhizoma Curcumae 12kg, Fructus Trichosanthis 7kg, Rhizoma Acori Graminei 7kg。
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 6 times of concentration of material quantity is the alcohol dipping of 60% after 7 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 100kg, standby;
(2) in the concentrated solution that step (1) prepares, add 1000kg water and 1kg potassium sorbate, stir evenly, stand 20-30h, Filter, obtain filtrate, standby;
(3) separately use 100kg sucrose, add 150kg water boil 40min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add 1000kg water, bottle after cooling, seal laggard Row sterilization treatment, makes product.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, select to accept 150 examples in patient for medical treatment, to medicine of the present invention Curative effect carry out clinical observation.In age 50-70 year, being randomly divided into 3 groups, often group is 50 examples, respectively experimental group 1-3 group.
Experimental group 1-3 group takes the medicine of embodiment 1-3 respectively, three times a day, takes 5g orally every time, within 12 days, is a course for the treatment of, Take 2-3 the course for the treatment of continuously.The most effective 138 examples, effective 142 examples, cure 135 examples, invalid 8 examples, cure rate 90%, effective percentage 94.7%.

Claims (7)

1., for treating a medicine for coronary heart disease, it is characterized in that: be mainly made up of the raw material of following weight parts proportioning:
Bulbus Allii Macrostemonis 10-15 part, Pericarpium Citri 5-7 part, Rhizoma Chuanxiong 8-12 part, Radix Ophiopogonis 8-12 part, Radix Paeoniae Alba 8-12 part, Flos Carthami 8-12 part, the most strongly fragrant Gold 8-12 part, Rhizoma Corydalis 8-10 part, Poria 8-12 part, Radix Salviae Miltiorrhizae 8-10 part, Radix Notoginseng 5-7 part, Rhizoma Polygonati Odorati 6-10 part, Fructus Schisandrae Chinensis 8-10 part, Rhizoma Curcumae 8-12 part, Fructus Trichosanthis 5-7 part, Rhizoma Acori Graminei 5-7 part.
Medicine for treating coronary heart disease the most according to claim 1, is characterized in that: the weight of each raw material is:
Bulbus Allii Macrostemonis 12 parts, Pericarpium Citri 6 parts, Rhizoma Chuanxiong 10 parts, Radix Ophiopogonis 10 parts, the Radix Paeoniae Alba 10 parts, 10 parts of Flos Carthami, RADIX CURCUMAE 10 parts, Rhizoma Corydalis 9 Part, 10 parts of Poria, Radix Salviae Miltiorrhizae 9 parts, Radix Notoginseng 6 parts, Rhizoma Polygonati Odorati 8 parts, Fructus Schisandrae Chinensis 9 parts, Rhizoma Curcumae 10 parts, Fructus Trichosanthis 6 parts, Rhizoma Acori Graminei 6 parts.
3., for treating a preparation method for the medicine of coronary heart disease, it is characterized in that: specifically comprise the following steps that
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, be mixed together and be placed in container, add After entering alcohol dipping 5-7 days of 4-6 times of concentration of material quantity, filter and remove residue, decompression filtrate recycling ethanol, to without alcohol taste, obtains concentrated solution 60-100 part is standby;
(2) in the concentrated solution that step (1) prepares, add water and potassium sorbate, stir evenly, stand 20-30h, filter, obtain filtrate, standby With;
(3) separately with sucrose, add water boil 30-40min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add water, bottle after cooling, seal after carry out sterilization treatment, Make product.
The preparation method of the medicine for treating coronary heart disease the most according to claim 3, is characterized in that: described step (1) The concentration of the ethanol of middle addition is 40-60%.
The preparation method of the medicine for treating coronary heart disease the most according to claim 3, is characterized in that: described step (2) The addition of middle water is 800-1000 part, and the addition of potassium sorbate is 0.8-1 part.
The preparation method of the medicine for treating coronary heart disease the most according to claim 3, is characterized in that: described step (3) In the amount of sucrose be 60-100 part, the amount of water is 100-150 part.
The preparation method of the medicine for treating coronary heart disease the most according to claim 3, is characterized in that: described step (4) The addition of middle water is 800-1000 part.
CN201610704359.6A 2016-08-22 2016-08-22 For treating the medicine of coronary heart disease Pending CN106075317A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107096000A (en) * 2017-05-26 2017-08-29 蒋田英 A kind of medicine for treating coronary heart disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497795A (en) * 2015-12-30 2016-04-20 杨桂珍 Medicine for treating coronary heart disease caused by stenocardia
CN105596981A (en) * 2015-12-30 2016-05-25 杨桂珍 Medicament for treating sudden cardiac death

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497795A (en) * 2015-12-30 2016-04-20 杨桂珍 Medicine for treating coronary heart disease caused by stenocardia
CN105596981A (en) * 2015-12-30 2016-05-25 杨桂珍 Medicament for treating sudden cardiac death

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107096000A (en) * 2017-05-26 2017-08-29 蒋田英 A kind of medicine for treating coronary heart disease

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