CN105497795A - Medicine for treating coronary heart disease caused by stenocardia - Google Patents
Medicine for treating coronary heart disease caused by stenocardia Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The invention discloses a medicine for treating a coronary heart disease caused by stenocardia. The medicine is mainly prepared from the following raw materials in parts by weight: 18-22 parts of trchosahthes kirilowii maxin, 10-15 parts of allium macrostemon, 8-12 parts of rhizoma pinellinae praeparata, 8-10 parts of amomum cardamomum, 5-7 parts of fructus aurantii, 8-10 parts of acorus calamus, 8-10 parts of cassia twig, 8-12 parts of flos carthami, 8-12 parts of ligusticum wallichii, 8-12 parts of radix curcumae, 8-10 parts of spina date seeds, 8-12 parts of radix ophiopogonis, 8-10 parts of schisandra chinensis, 8-12 parts of poria cocos, 5-7 parts of panax notoginseng and 6-10 parts of radix polygonati officinalis. According to the medicine for treating the coronary heart disease caused by stenocardia, 16 natural traditional Chinese medicines are selected for scientific combination; the formula is simple; various raw materials work together to achieve the efficacies of regulating qi, activating blood circulation, dredging collaterals and relieving pain; the medicine is fast in acting, free of a toxic or side effect, simple in preparation method, convenient to take and low in cost and is capable of treating both symptoms and root causes; and the effective rate reaches 95% or over.
Description
Technical field
The present invention relates to Chinese medicine, specifically a kind of medicine being used for the treatment of angina pectoris coronary heart disease.
Background technology
Coronary heart disease is the common a kind of cardiovascular disease of middle-aged and elderly people, is uneven between coronary blood flow because the functional change of coronary artery or organic disease cause and myocardial demand and cardiac damage that is that cause.The basic lesion of primary disease be supply myocardial nutrition material blood vessel---coronary artery there occurs atherosis, therefore its full name is coronary atherosclerotic heart disease, referred to as coronary heart disease.Main manifestations is angina pectoris, arrhythmia, heart failure, may die suddenly.Electrocardiogram, myocardium enzyme mensuration, radio nuclide examination and coronarography can be clarified a diagnosis further.Control generation and development that blood pressure, blood fat, body weight and smoking cessation effectively can prevent coronary heart disease.
The risk factor of coronary heart disease comprises changeable risk factor and unmodifiable risk factor.Understand and intervene the control that risk factor contributes to coronary heart disease.Changeable risk factor has: hypertension, dyslipidemia (T-CHOL is too high or low-density lipoprotein cholesterol is too high, triglyceride is too high, HDL-C too low), overweight/obesity, hyperglycemia/diabetes, bad life style comprises smoking, unreasonable meals (higher fatty acid, hypercholesterolemia, high heat etc.), lacks physical exertion, excessive consumption of alcohol, and socio-psychological factors.Unmodifiable risk factor has: sex, age, family history.In addition, relevant with infection, as cytomegalovirus, Chlamydia pneumoniae, helicobacter pylori etc.The outbreak of coronary heart disease usually with seasonal variations, excited, physical exertion increases, be satiated with food, a large amount of smoking and to drink etc. relevant.
Present is main mainly with Western medicine and operative treatment, but side effect is comparatively large, and easily recurs, and can not effect a radical cure, cause certain burden to patient's economy and physiology.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, treatment cycle is long, and curative effect is not remarkable.
Summary of the invention
The object of this invention is to provide the medicine being used for the treatment of angina pectoris coronary heart disease that a kind of good effect, short treating period, cost are low, have no side effect.
The technical scheme realizing the object of the invention is:
Be used for the treatment of a medicine for angina pectoris coronary heart disease, the raw material primarily of following weight parts proportioning is made:
Fructus Trichosanthis 18-22 part, Bulbus Allii Macrostemonis 10-15 part, Rhizoma Pinelliae Preparatum 8-12 part, roud cardamon seed 8-10 part, Fructus Aurantii 5-7 part, Rhizoma Acori Graminei 8-10 part, Ramulus Cinnamomi 8-10 part, Flos Carthami 8-12 part, Rhizoma Chuanxiong 8-12 part, RADIX CURCUMAE 8-12 part, Semen Ziziphi Spinosae 8-10 part, Radix Ophiopogonis 8-12 part, Fructus Schisandrae Chinensis 8-10 part, Poria 8-12 part, Radix Notoginseng 5-7 part, Rhizoma Polygonati Odorati 6-10 part.
The above-mentioned medicine being used for the treatment of angina pectoris coronary heart disease, optimum weight part proportioning of each raw material is:
Fructus Trichosanthis 20 parts, Bulbus Allii Macrostemonis 12 parts, Rhizoma Pinelliae Preparatum 10 parts, roud cardamon seed 9 parts, Fructus Aurantii 6 parts, Rhizoma Acori Graminei 9 parts, Ramulus Cinnamomi 9 parts, 10 parts, Flos Carthami, Rhizoma Chuanxiong 10 parts, RADIX CURCUMAE 10 parts, Semen Ziziphi Spinosae 9 parts, Radix Ophiopogonis 10 parts, Fructus Schisandrae Chinensis 9 parts, 10 parts, Poria, Radix Notoginseng 6 parts, Rhizoma Polygonati Odorati 8 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 35-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Fructus Trichosanthis: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.
Bulbus Allii Macrostemonis: activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen feeling of fullness distending pain, heavy after dysentery.
Rhizoma Pinelliae Preparatum: drying dampness to eliminate phlegm.For dry laryngopharynx, abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache.
Roud cardamon seed: have regulating the flow of QI to ease the stomach, dry cold-damp, effect of alcoholic intoxication.Can to treat for stomachache the disease such as abdominal distention, eructation regurgitation.
Fructus Aurantii: there is regulating the flow of QI to ease the stomach, effect of the stagnant relieving distension of row.Be usually used in the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, visceroptosis.
Rhizoma Acori Graminei: reduce phlegm, has one's ideas straightened out, spleen invigorating, dampness removing.For epilepsy, palpitate with fear forgetful, obnubilation, humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies.
Ramulus Cinnamomi: there is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, effect of the flat gas that spins.Be usually used in anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus etc.
Flos Carthami: there is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, injury from falling down, skin infection swells and ache.
Rhizoma Chuanxiong: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
RADIX CURCUMAE: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, promoting the function of the gallbladder to alleviate jaundice.
Semen Ziziphi Spinosae: nourishing the liver, mind calming, calms the nerves, arresting sweating.Control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.
Radix Ophiopogonis: Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, clear away heart-fire relieving restlessness, cure mainly consumption of body fluid caused by febrile disease, vexed, thirsty, dry pharynx lung-heat, cough, pulmonary tuberculosis Radix Ophiopogonis.
Fructus Schisandrae Chinensis: there is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming.Be usually used in chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Notoginseng: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Rhizoma Polygonati Odorati: there is nourishing YIN to relieve dryness, effect of promoting the production of body fluid to quench thirst.Be usually used in lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
The present invention is used for the treatment of the medicine of angina pectoris coronary heart disease, and choose 16 kinds of natural Chinese medicine scientific compatibility, formula is simple, each crude drug synergism plays the effect of vital energy regualting and blood circulation-promoting, removing obstruction in the collateral to relieve pain, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
Be used for the treatment of a medicine for angina pectoris coronary heart disease, the raw material primarily of following weight parts proportioning is made:
Fructus Trichosanthis 18kg, Bulbus Allii Macrostemonis 10kg, Rhizoma Pinelliae Preparatum 8kg, roud cardamon seed 8kg, Fructus Aurantii 5kg, Rhizoma Acori Graminei 8kg, Ramulus Cinnamomi 8kg, Flos Carthami 8kg, Rhizoma Chuanxiong 8kg, RADIX CURCUMAE 8kg, Semen Ziziphi Spinosae 8kg, Radix Ophiopogonis 8kg, Fructus Schisandrae Chinensis 8kg, Poria 8kg, Radix Notoginseng 5kg, Rhizoma Polygonati Odorati 6kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 35min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.
Embodiment 2
Be used for the treatment of a medicine for angina pectoris coronary heart disease, the raw material primarily of following weight parts proportioning is made:
Fructus Trichosanthis 20kg, Bulbus Allii Macrostemonis 12kg, Rhizoma Pinelliae Preparatum 10kg, roud cardamon seed 9kg, Fructus Aurantii 6kg, Rhizoma Acori Graminei 9kg, Ramulus Cinnamomi 9kg, Flos Carthami 10kg, Rhizoma Chuanxiong 10kg, RADIX CURCUMAE 10kg, Semen Ziziphi Spinosae 9kg, Radix Ophiopogonis 10kg, Fructus Schisandrae Chinensis 9kg, Poria 10kg, Radix Notoginseng 6kg, Rhizoma Polygonati Odorati 8kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 4 times of material quantity weight 15 times, decoct 38min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 54 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 3
Be used for the treatment of a medicine for angina pectoris coronary heart disease, the raw material primarily of following weight parts proportioning is made:
Fructus Trichosanthis 22kg, Bulbus Allii Macrostemonis 15kg, Rhizoma Pinelliae Preparatum 12kg, roud cardamon seed 10kg, Fructus Aurantii 7kg, Rhizoma Acori Graminei 10kg, Ramulus Cinnamomi 10kg, Flos Carthami 12kg, Rhizoma Chuanxiong 12kg, RADIX CURCUMAE 12kg, Semen Ziziphi Spinosae 10kg, Radix Ophiopogonis 12kg, Fructus Schisandrae Chinensis 10kg, Poria 12kg, Radix Notoginseng 7kg, Rhizoma Polygonati Odorati 10kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 42min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 58 DEG C, add adjuvant, make pill, every 0.4g.
Embodiment 4
Be used for the treatment of a medicine for angina pectoris coronary heart disease, the raw material primarily of following weight parts proportioning is made:
Fructus Trichosanthis 22kg, Bulbus Allii Macrostemonis 15kg, Rhizoma Pinelliae Preparatum 12kg, roud cardamon seed 10kg, Fructus Aurantii 7kg, Rhizoma Acori Graminei 10kg, Ramulus Cinnamomi 10kg, Flos Carthami 12kg, Rhizoma Chuanxiong 12kg, RADIX CURCUMAE 12kg, Semen Ziziphi Spinosae 10kg, Radix Ophiopogonis 12kg, Fructus Schisandrae Chinensis 10kg, Poria 12kg, Radix Notoginseng 7kg, Rhizoma Polygonati Odorati 10kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 45min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 200 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 50-70 year, be divided into 4 groups at random, often group be 50 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 2 times, each 4 slices/for oral administration, within 10 days, is a course for the treatment of, takes 1-2 the course for the treatment of continuously.Wherein effective 188 examples, effective 190 examples, cure 185 examples, invalid 10 examples, cure rate 92.5%, effective percentage 95%.
Claims (3)
1. be used for the treatment of a medicine for angina pectoris coronary heart disease, it is characterized in that: the raw material primarily of following weight parts proportioning is made:
Fructus Trichosanthis 18-22 part, Bulbus Allii Macrostemonis 10-15 part, Rhizoma Pinelliae Preparatum 8-12 part, roud cardamon seed 8-10 part, Fructus Aurantii 5-7 part, Rhizoma Acori Graminei 8-10 part, Ramulus Cinnamomi 8-10 part, Flos Carthami 8-12 part, Rhizoma Chuanxiong 8-12 part, RADIX CURCUMAE 8-12 part, Semen Ziziphi Spinosae 8-10 part, Radix Ophiopogonis 8-12 part, Fructus Schisandrae Chinensis 8-10 part, Poria 8-12 part, Radix Notoginseng 5-7 part, Rhizoma Polygonati Odorati 6-10 part.
2. the medicine being used for the treatment of angina pectoris coronary heart disease according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:
Fructus Trichosanthis 20 parts, Bulbus Allii Macrostemonis 12 parts, Rhizoma Pinelliae Preparatum 10 parts, roud cardamon seed 9 parts, Fructus Aurantii 6 parts, Rhizoma Acori Graminei 9 parts, Ramulus Cinnamomi 9 parts, 10 parts, Flos Carthami, Rhizoma Chuanxiong 10 parts, RADIX CURCUMAE 10 parts, Semen Ziziphi Spinosae 9 parts, Radix Ophiopogonis 10 parts, Fructus Schisandrae Chinensis 9 parts, 10 parts, Poria, Radix Notoginseng 6 parts, Rhizoma Polygonati Odorati 8 parts.
3. the medicine being used for the treatment of angina pectoris coronary heart disease according to claim 1, is characterized in that:
Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 35-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
Priority Applications (1)
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CN106075317A (en) * | 2016-08-22 | 2016-11-09 | 黄琴 | For treating the medicine of coronary heart disease |
CN107096000A (en) * | 2017-05-26 | 2017-08-29 | 蒋田英 | A kind of medicine for treating coronary heart disease |
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CN103768501A (en) * | 2012-10-25 | 2014-05-07 | 曹红云 | Preparation method of traditional Chinese medicine for treating angina pectoris |
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CN103768501A (en) * | 2012-10-25 | 2014-05-07 | 曹红云 | Preparation method of traditional Chinese medicine for treating angina pectoris |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106075317A (en) * | 2016-08-22 | 2016-11-09 | 黄琴 | For treating the medicine of coronary heart disease |
CN107096000A (en) * | 2017-05-26 | 2017-08-29 | 蒋田英 | A kind of medicine for treating coronary heart disease |
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