CN105606418A - 一种检测糖化血红蛋白的一体化试剂盒及其检测方法 - Google Patents
一种检测糖化血红蛋白的一体化试剂盒及其检测方法 Download PDFInfo
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- CN105606418A CN105606418A CN201511015703.2A CN201511015703A CN105606418A CN 105606418 A CN105606418 A CN 105606418A CN 201511015703 A CN201511015703 A CN 201511015703A CN 105606418 A CN105606418 A CN 105606418A
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- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 claims description 20
- 102000001554 Hemoglobins Human genes 0.000 claims description 15
- 108010054147 Hemoglobins Proteins 0.000 claims description 15
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 15
- 239000000376 reactant Substances 0.000 claims description 11
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 10
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 10
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- HXITXNWTGFUOAU-UHFFFAOYSA-N phenylboronic acid Chemical compound OB(O)C1=CC=CC=C1 HXITXNWTGFUOAU-UHFFFAOYSA-N 0.000 claims description 9
- 238000011026 diafiltration Methods 0.000 claims description 6
- BHNQPLPANNDEGL-UHFFFAOYSA-N 2-(4-octylphenoxy)ethanol Chemical compound CCCCCCCCC1=CC=C(OCCO)C=C1 BHNQPLPANNDEGL-UHFFFAOYSA-N 0.000 claims description 5
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- 238000012360 testing method Methods 0.000 description 9
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- 206010012601 diabetes mellitus Diseases 0.000 description 7
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- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 4
- 239000004327 boric acid Substances 0.000 description 4
- 238000001962 electrophoresis Methods 0.000 description 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 3
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- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
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- 108010044495 Fetal Hemoglobin Proteins 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
干扰项 | 浓度 | HbAlc理论浓度 | HbAlc实测浓度 | 回收率 |
葡萄糖 | 140mmol/L | 9.6% | 9.8% | 102% |
总胆红素 | 430.3μmol/L | 9.6% | 9.7% | 101% |
甘油三酯 | 39.8mmol/L | 9.6% | 10.1% | 105% |
EDTA-K2 | --- | 9.6% | 9.5% | 99% |
肝素 | --- | 9.6% | 9.7% | 101% |
枸橼酸钠 | --- | 9.6% | 9.5% | 99% |
Claims (10)
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CN201511015703.2A CN105606418A (zh) | 2015-12-30 | 2015-12-30 | 一种检测糖化血红蛋白的一体化试剂盒及其检测方法 |
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CN201511015703.2A CN105606418A (zh) | 2015-12-30 | 2015-12-30 | 一种检测糖化血红蛋白的一体化试剂盒及其检测方法 |
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CN105606418A true CN105606418A (zh) | 2016-05-25 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107153121A (zh) * | 2017-04-12 | 2017-09-12 | 深圳市东邦生物医疗技术有限公司 | 糖化血红蛋白、血红蛋白检测试剂盒及其检测方法 |
CN107255724A (zh) * | 2017-01-03 | 2017-10-17 | 深圳市惠安生物科技有限公司 | 糖化血红蛋白的即时检验试剂装置及其制备方法 |
CN111194241A (zh) * | 2017-09-05 | 2020-05-22 | 拜克门寇尔特公司 | 收集并准备用于即时诊断的血液样品 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
CN101238374A (zh) * | 2005-06-13 | 2008-08-06 | 日本化药株式会社 | 使用全血的血液成分测定方法及测定试剂盒 |
CN101408549A (zh) * | 2007-10-08 | 2009-04-15 | 因福皮亚有限公司 | 用于检测糖化血红蛋白浓度的反应盒及其检测方法 |
CN102998289A (zh) * | 2012-11-14 | 2013-03-27 | 广西安仁欣生物科技有限公司 | 基于核酸适体荧光探针的糖化血红蛋白试剂盒及其检测方法 |
CN103245791A (zh) * | 2013-05-02 | 2013-08-14 | 深圳市凯特生物医疗电子科技有限公司 | 一种一体化低压离子交换糖化血红蛋白分析仪 |
CN103674938A (zh) * | 2012-09-10 | 2014-03-26 | 长沙颐康科技开发有限公司 | 缺血修饰白蛋白组合测定试剂、测定方法及试剂盒 |
CN104884466A (zh) * | 2012-12-20 | 2015-09-02 | 狮王株式会社 | 高血糖风险判定用标记肽及其用途 |
CN104897907A (zh) * | 2015-05-21 | 2015-09-09 | 广东优尼德生物科技有限公司 | 一种检测糖化血红蛋白的试剂盒及其检测方法 |
CN104965085A (zh) * | 2014-03-26 | 2015-10-07 | 迪亚贝托米克斯有限公司 | 用于诊断和监测糖尿病的唾液蛋白糖基化测试 |
-
2015
- 2015-12-30 CN CN201511015703.2A patent/CN105606418A/zh active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
CN101238374A (zh) * | 2005-06-13 | 2008-08-06 | 日本化药株式会社 | 使用全血的血液成分测定方法及测定试剂盒 |
CN101408549A (zh) * | 2007-10-08 | 2009-04-15 | 因福皮亚有限公司 | 用于检测糖化血红蛋白浓度的反应盒及其检测方法 |
CN103674938A (zh) * | 2012-09-10 | 2014-03-26 | 长沙颐康科技开发有限公司 | 缺血修饰白蛋白组合测定试剂、测定方法及试剂盒 |
CN102998289A (zh) * | 2012-11-14 | 2013-03-27 | 广西安仁欣生物科技有限公司 | 基于核酸适体荧光探针的糖化血红蛋白试剂盒及其检测方法 |
CN104884466A (zh) * | 2012-12-20 | 2015-09-02 | 狮王株式会社 | 高血糖风险判定用标记肽及其用途 |
CN103245791A (zh) * | 2013-05-02 | 2013-08-14 | 深圳市凯特生物医疗电子科技有限公司 | 一种一体化低压离子交换糖化血红蛋白分析仪 |
CN104965085A (zh) * | 2014-03-26 | 2015-10-07 | 迪亚贝托米克斯有限公司 | 用于诊断和监测糖尿病的唾液蛋白糖基化测试 |
CN104897907A (zh) * | 2015-05-21 | 2015-09-09 | 广东优尼德生物科技有限公司 | 一种检测糖化血红蛋白的试剂盒及其检测方法 |
Non-Patent Citations (1)
Title |
---|
FRANK FRANTZEN ET AL.: "Glycohemoglobin filter assay for doctors’offices based on boronic acid affinity principle", 《CLINICAL CHEMISTRY》 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107255724A (zh) * | 2017-01-03 | 2017-10-17 | 深圳市惠安生物科技有限公司 | 糖化血红蛋白的即时检验试剂装置及其制备方法 |
CN107153121A (zh) * | 2017-04-12 | 2017-09-12 | 深圳市东邦生物医疗技术有限公司 | 糖化血红蛋白、血红蛋白检测试剂盒及其检测方法 |
CN111194241A (zh) * | 2017-09-05 | 2020-05-22 | 拜克门寇尔特公司 | 收集并准备用于即时诊断的血液样品 |
US11666917B2 (en) | 2017-09-05 | 2023-06-06 | Beckman Coulter, Inc. | Collection and preparation of blood samples for point-of-care diagnostics |
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