CN105596273A - Soothing, moistening, brightening and whitening emulsion and preparation method thereof - Google Patents
Soothing, moistening, brightening and whitening emulsion and preparation method thereof Download PDFInfo
- Publication number
- CN105596273A CN105596273A CN201510829840.3A CN201510829840A CN105596273A CN 105596273 A CN105596273 A CN 105596273A CN 201510829840 A CN201510829840 A CN 201510829840A CN 105596273 A CN105596273 A CN 105596273A
- Authority
- CN
- China
- Prior art keywords
- weight portion
- extract
- emulsion
- glycerine
- fragrant citrus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Abstract
The invention specifically relates to a soothing, moistening, brightening and whitening emulsion and a preparation method thereof, belonging to the technical field of cosmetics. The emulsion comprises extract of Radix Glycyrrhizae glabrae, macadimia nut oil, artemia extract, tremella extract, fragrant citrus fruit extract and ethylhexylglycerin. Whitening components of the emulsion is obtained through screening; after addition of the whitening components in a cosmetic matrix, the melanin value and melanin content of the skin can be reduced; thus, the emulsion has good inhibitory effect on melanin, i.e., good whitening effect. Moreover, through addition of citric acid and sodium citrate into the whitening emulsion, stability of the emulsion is guaranteed.
Description
Technical field
The invention belongs to cosmetics technical field, be specifically related to clear Virgin's milk liquid of a kind of Shu Run and preparation method thereof.
Background technology
Skin-whitening and nursing are the themes of cosmetics, have the cosmetics of skin-whitening and skin-care functionOne of best-selling cosmetics. Modern scientific research proves, skin aging is a very complicated process,Be subject to the impact of many factors, wherein melanic generation and free radical cause that the sex change of elastic fibers of skin isTwo large principal elements. Melanic forming process is: the tyrosine (tyrosine) in human body skin melanocyteOxidized generation DOPA (dopa) and DOPA quinone (dopaquinone) under the catalytic action of tyrosinase,Generate dopachrome (dopachrome), 5 through resetting laggard oxidation step, 6-dihydroxy indole (5,6-dihydroxyindole), istain (indole-5,6-quinone), finally synthesis of melanin (melanin).The principal element that affects melanic formation has: the quantity of melanocyte, the activity of tyrosinase, oxygen are certainlyBy the content of base and the content of tyrosine. Wherein, tyrosine is the amino acid of needed by human, its content be byHuman body self is controlled. So, control melanic formation, can only be by controlling the number of melanocyteAmount, the activity of tyrosinase and the content of oxygen radical. So, from the angle of safety, skin-whiteningMainly contain the following aspects with the approach of skin nursing: the one, by suppressing dermal melanin cell proliferation,Reduce the quantity that melanocyte generates; The 2nd, the key enzyme-tyrosinase generating by suppressing dermal melaninCatalytic activity, reach whitening object thereby reduce melanic generating rate; The 3rd, by sun-proof, preventThe injury (tanned and sunburn) of sunlight middle-ultraviolet lamp to skin, slows down skin aging; The 4th, by using antioxygenThe oxygen radical in skin is removed in agent, slows down melanin generation and slows down skin aging. At present, China's whiteningAll there is larger defect in the management of cosmetics and technology, the phenomenon of adding is in violation of rules and regulations very serious, have even withThe contrabands such as aminomercuric chloride are bleached as peroxide such as whitening agent or interpolation hydrogen peroxide, make for many yearsBecome many beauty treatment accidents, even disfeatured, caused very large injury to consumer, caused country andConsumer's great attention. In recent years, the whitening agent using in cosmetics mainly contain hydroquinones (quinhydrones),The compounds such as L-AA (vitamin C), kojic acid, superoxide dismutase (SOD) and ursin.But these whitening agents exist many defects, as the excitant of quinhydrones is very large, vitamin C and SOD are veryUnstable, kojic acid also has certain excitant and property easy to change, the single and poor effect of ursin effect etc.So exploitation has good safety, stability, inhibition is obvious, the natural whiting agent that cost performance is good,Become one of main direction of studying of current medicine and cosmetic industry, there is extraordinary development prospect.Natural materials is applied to cosmetics can reach skin treating and skin care double effects, and have diverse in function,The characteristic such as widely applicable, safe, thereby day by day come into one's own. Patent of invention CN102225039A has announcedContaining a whitening Chinese medicament composition for Radix Glycyrrhizae, moutan bark, tribulus terrestris, sealwort, motherwort, this Chinese traditional medicine compositionThing adopts decocting method to extract preparation. Patent of invention CN101612105 has announced a kind of by the bletilla striata, whiteHold back, the extract of the root bark of white mulberry, PORIA ALBA, tribulus terrestris, the bighead atractylodes rhizome, Amomum cardamomum, the root of herbaceous peony, pyrola and Radix Angelicae SinensisWhitening and skin-protecting Chinese medicine composition of composition and preparation method thereof, said composition adopts to soak and extracts and resin isolationThe method preparation of enrichment. Patent of invention CN101732223A has announced a kind of by aloe, white lilac, Bai QianOx, PORIA ALBA, gingko benevolence, the bletilla striata, the root of Dahurain angelica, the bighead atractylodes rhizome, bird's nest, heart of a lotus seed benevolence, felwort, Radix Angelicae Sinensis, ginkgoThe pure Chinese medicine active white skin care solution of composition, this Chinese medicine composition adopts decocting method to extract preparation. Invention speciallyProfit CN101804185A has announced a kind of containing radix bupleuri, Radix Angelicae Sinensis, the root of herbaceous peony, Fructus Corni, the bighead atractylodes rhizome, Poria cocos, riverThe nti-freckle Chinese medicine composition of rhizome of chuanxiong, peach kernel, the larva of a silkworm with batrytis, stewing ginger, peppermint and honey-fried licorice root, this Chinese medicine composition is adoptedWith employing carbon dioxide supercritical extraction technology extract. Above-mentioned Chinese medicine composition adds cosmetic baseIn, although can solve the problem of skin-lightening cosmetic excitant, stability, these cosmetic appearance are poor,Whitening effect need to be longer time, therefore, further research and develop better skin-lightening cosmetic, have heavilyWant meaning.
Summary of the invention
For these reasons, applicant, through years of researches, obtains a kind of new emulsion, in this emulsion, containsHave whitening composition, whitening composition comprises: glycyrrhiza glabra root extract, Queensland nut oil, halogen worm extract,Dried tremella extract, fragrant citrus berry extract, Sensiva SC50. Whitening composition of the present invention is to obtain by screening, in cosmetic base, add above-mentioned whitening composition, the Mai Laning value that can well reduce skin withAnd Mai Laning content, absolutely prove that emulsion of the present invention has the effect of good check melanin, has veryGood whitening function; In addition, in whitening emulsion, add citric acid and natrium citricum, ensure the stability of emulsion.
The present invention is achieved through the following technical solutions.
A kind of emulsion, described emulsion comprises whitening composition, wherein whitening composition is: glycyrrhiza glabra root extract,Queensland nut oil, halogen worm extract, dried tremella extract, fragrant citrus berry extract, Sensiva SC50.
Wherein glycyrrhiza glabra root extract 1-3 weight portion, Queensland nut oil 0.5-1.5 weight portion, halogen worm are extractedThing 0.0001 weight portion, dried tremella extract 0.04-0.06 weight portion, fragrant citrus berry extract 0.000003 weight portion,Sensiva SC50 0.1-0.3 weight portion.
Described emulsion comprises: 1,3-BDO, betaine, 1,2-pentanediol, saualane, poly dimethylSiloxanes, cetostearyl alcohol, glycerine, sucrose stearate, sucrose distearate, isononyl isononanoate,1,2-hexylene glycol, two (lauramide glutamine) Sodium lysinate, two-bis-many acyl groups of glycerine adipate ester-2,Pungent glycol, PEG-45 stearate, beta glucan, Sensiva SC50, tocopherol, arginine, poly-Acrylic acid, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, xanthans, hydrolecithin,Platinum powder, natrium citricum, citric acid, Denatonium Benzoate, licorice root extract, Queensland nut oil, halogen worm are carriedGet thing, dried tremella extract, fragrant citrus berry extract.
Described emulsion comprises: 1,3-BDO 6-8 weight portion, betaine 4-6 weight portion, 1,2-pentanediol2-4 weight portion, saualane 2-4 weight portion, dimethyl silicone polymer 2-4 weight portion, cetostearyl alcohol 2-3Weight portion, glycerine 1.5-2.5 weight portion, sucrose stearate 0.5-1.5 weight portion, sucrose distearate0.5-1.5 weight portion, isononyl isononanoate 0.5-0.7 weight portion, 1,2-hexylene glycol 0.6-0.8 weight portion, two(lauramide glutamine) Sodium lysinate 0.04-0.06 weight portion, two-bis-many acyl groups of glycerine adipate ester-20.4-0.6 weight portion, pungent glycol 0.07-0.08 weight portion, PEG-45 stearate 0.2-0.4 weight portion, β-glucan 0.001-0.002 weight portion, Sensiva SC50 0.1-0.3 weight portion, tocopherol 0.05-0.15 weighAmount part, arginine 0.1-0.3 weight portion, polyacrylic acid 0.1-0.3 weight portion, hydrolyzed vegetable protein 0.002-0.003Weight portion, atriphos 0.002-0.003 weight portion, sodium chondroitin sulfate 0.002-0.003 weight portion, HuangVirgin rubber 0.04-0.06 weight portion, hydrolecithin 0.04-0.06 weight portion, platinum powder 0.0000002 weight portion,Natrium citricum 0.01 weight portion, citric acid 0.003 weight portion, Denatonium Benzoate 0.00002 weight portion, light fruitLicorice root extract 1-3 weight portion, Queensland nut seed oil 0.5-1.5 weight portion, halogen worm extract 0.0001 weightAmount part, dried tremella extract 0.04-0.06 weight portion, fragrant citrus berry extract 0.000003 weight portion.
The preparation method of described emulsion is:
(1) water intaking, glycerine, hydrolecithin, 1,3-BDO, betaine, xanthans, polyacrylic acid,Sensiva SC50, tocopherol, 1,2-hexylene glycol, pungent glycol, two (lauramide glutamine) lysineSodium, adds water pot, is heated to, after 65-70 DEG C, stir, in suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol, add oil phase pot, is heated to 65-70 DEG C, stirs, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water, glycerine, 1,2-hexylene glycol, 1,2-pentanediol, beta glucan, arginine, 1,3-BDO, waterSeparate vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, dried tremella extract, platinum powder,Natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, Denatonium Benzoate, continue to stirMix evenly, be cooled to room temperature; Filling, to obtain final product.
Described glycyrrhiza glabra root extract, Queensland nut oil, halogen worm extract, dried tremella extract and fragrant citrus fruitExtract is in the application of preparing in skin-lightening cosmetic.
Described glycyrrhiza glabra (GLYCYRRHIZAGLABRA) root extract, purchased from OLIEnterprises,Lot number 2014082703.
Described Queensland nut (MACADAMIATERNIFOLIA) oil, purchased from NorthstarLipids,Lot number MNOCBFCL3500608.
Described white fungus (TREMELLAFUCIFORMIS) extract, purchased from brightness literary composition, lot number 150801.Described halogen worm (ARTEMIA) extract, purchased from ISP, lot number 5001912450.
Described fragrant citrus (CITRUSJUNOS) berry extract,, purchased from ICHIMARU, lot number 150934。
Detailed description of the invention
Below in conjunction with example, the present invention is elaborated. Following examples do not limit protection of the present inventionScope.
Following test, is on the basis of repeatedly creative test, for the claimed content of the present invention,The concluding test of carrying out.
One, screening test
Test 1 group: glycyrrhiza glabra root extract 2g, Queensland nut oil 1g.
Test 2 groups: glycyrrhiza glabra root extract 2g, Queensland nut oil 1g, dried tremella extract 0.05g.
Test 3 groups: glycyrrhiza glabra root extract 2g, Queensland nut oil 1g, halogen worm extract 0.0001g,Dried tremella extract 0.05g, fragrant citrus berry extract 0.000003g, Sensiva SC50 0.2g.
Test 4 groups: glycyrrhiza glabra root extract 2g, Queensland nut oil 1g, halogen worm extract 0.001g, silverEar extract 0.05g, fragrant citrus berry extract 0.00003g, Sensiva SC50 0.2g.
Test 5 groups: glycyrrhiza glabra root extract 2g, Queensland nut oil 1g, halogen worm extract 0.1g, white fungusExtract 0.05g, fragrant citrus berry extract 0.3g, Sensiva SC50 0.2g.
Test specimen preparation: get 1,3-BDO 5g, the 5g that adds water, mixes completely. Get 1 group of raw material of test,Add in above-mentioned solvent, mix completely, for subsequent use; Test 5 groups of 2 groups-tests, compound method is the same.
Test method: get human body skin threedimensional model test box (MEL-300B). According to this test operation flow processThreedimensional model is moved in 6 porocyte culture plates, be placed in long term maintenance culture medium (EPI-100LLMM)37℃，5％CO2Lower insulating box preculture, after 1 hour, adds the test specimen of different tests group, adds respectivelyPrepare test specimen 100 μ L to cuticula side, blank group adds the 1,3-BDO aqueous solution (50%) of equivalent.Basalis side is used long term maintenance culture medium to continue to cultivate. Interval exchange culture medium and the tested material of 2 days or 3 daysCarry out altogether the cultivation of 16 days. After cultivation, wash after skin histology by PBS (-) buffering, utilize MX18(manufacture of Courage+Khazaka company) tests the Mai Laning value of different groups.
Result of the test: in table 1.
The Mai Laning value of table 1 different tests group
| Test group | Mai Laning value (a.u.) |
| Blank group | 493.2±1.9 |
| Test 1 group | 389.1±0.8** |
| Test 2 groups | 374.5±0.7** |
| Test 3 groups | 302.1±1.2*** |
| Test 4 groups | 312.7±0.8*** |
| Test 5 groups | 305.4±1.0*** |
Note: with relatively * * P < 0.01 of blank group, * * * P < 0.001.
Conclusion (of pressure testing): known Mai Laning value is lower, illustrates that the ability of check melanin is stronger; Above-mentioned test numberAccording to showing, after glycyrrhiza glabra root extract and the combination of Queensland nut oil, (testing 1 group) can well suppress blackPigment, adds after dried tremella extract, does not improve whitening effect, but add micro-halogen worm extract andAfter fragrant citrus berry extract and Sensiva SC50, Mai Laning value reduces (with relatively P < 0.001 of blank group) greatly,But after the amount of halogen worm extract and fragrant citrus berry extract is increased, not further raising check melaninAbility, therefore, applicant determines that the composition of 3 groups of tests is whitening composition.
Two, demonstration test
Test 1 group: 1,3-BDO 6g, betaine 4g, 1,2-pentanediol 2g, saualane 2g, poly-Dimethyl siloxane 2g, cetostearyl alcohol 2g, glycerine 1.5g, sucrose stearate 0.5g, sucrose distearylAcid esters 0.5g, isononyl isononanoate 0.5g, 1,2-hexylene glycol 0.6g, two (lauramide glutamine) reliesPropylhomoserin sodium 0.04g, two-bis-many acyl groups of glycerine adipate ester-20.4g, pungent glycol 0.07g, PEG-45 tristearinAcid esters 0.2g, beta glucan 0.001g, Sensiva SC50 0.1g, tocopherol 0.05g, arginine 0.1g,Polyacrylic acid 0.1g, hydrolyzed vegetable protein 0.002g, atriphos 0.002g, sodium chondroitin sulfate 0.002g,Xanthans 0.04g, hydrolecithin 0.04g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g,Denatonium Benzoate 0.00002g, glycyrrhiza glabra root extract 1g, Queensland nut seed oil 0.5g, halogen worm extract0.0001g, dried tremella extract 0.04g, fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 55g, glycerine 0.7g, hydrolecithin, 1,3-BDO 3g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.02g, 1,2-hexylene glycol 0.3g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.03g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 5g, glycerine 0.8g, 1,2-hexylene glycol 0.3g, 1,2-pentanediol, beta glucan, arginine, 1,3-fourthGlycol 3g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungus extractThing, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene first ground thatAmmonium, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Test 2 groups: 1,3-BDO 7g, betaine 5g, 1,2-pentanediol 3g, saualane 3g, poly-Dimethyl siloxane 3g, cetostearyl alcohol 2.5g, glycerine 2g, sucrose stearate 1g, the acid of sucrose distearylEster 1g, isononyl isononanoate 0.6g, 1,2-hexylene glycol 0.7g, two (lauramide glutamine) lysineSodium 0.05g, two-bis-many acyl groups of glycerine adipate ester-20.5g, pungent glycol 0.075g, PEG-45 stearic acidEster 0.3g, beta glucan 0.0015g, Sensiva SC50 0.2g, tocopherol 0.1g, arginine 0.2g, poly-Acrylic acid 0.2g, hydrolyzed vegetable protein 0.0025, atriphos 0.0025g, sodium chondroitin sulfate 0.0025g,Xanthans 0.05g, hydrolecithin 0.05g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g,Denatonium Benzoate 0.00002g, glycyrrhiza glabra root extract 2g, Queensland nut seed oil 1g, halogen worm extract0.0001g, dried tremella extract 0.05g, fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 62g, glycerine 1g, hydrolecithin, 1,3-BDO 3.5g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.05g, 1,2-hexylene glycol 0.35g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.05g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 9g, glycerine 1g, 1,2-hexylene glycol 0.35g, 1,2-pentanediol, beta glucan, arginine, 1,3-fourthGlycol 3.5g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungus extractThing, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene first ground thatAmmonium, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Test 3 groups: 1,3-BDO 8g, betaine 6g, 1,2-pentanediol 4g, saualane 4g, poly-diformazanRadical siloxane 4g, cetostearyl alcohol 3g, glycerine 2.5g, sucrose stearate 1.5g, sucrose distearate 1.5g,Isononyl isononanoate 0.7g, 1,2-hexylene glycol 0.8g, two (lauramide glutamine) Sodium lysinate 0.06g,Two-bis-many acyl groups of glycerine adipate ester-20.6g, pungent glycol 0.08g, PEG-45 stearate 0.4g, β-Glucan 0.002g, Sensiva SC50 0.3g, tocopherol 0.15g, arginine 0.3g, polyacrylic acid 0.3g,Hydrolyzed vegetable protein 0.003g, atriphos 0.003g, sodium chondroitin sulfate 0.003g, xanthans 0.06g,Hydrolecithin 0.06g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g, benzene first ground thatAmmonium 0.00002g, glycyrrhiza glabra root extract 2g, Queensland nut seed oil 1g, halogen worm extract 0.0001g, silverEar extract 0.05g, fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 70g, glycerine 1.2g, hydrolecithin, 1,3-BDO 4g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.07g, 1,2-hexylene glycol 0.4g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.08g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 11g, glycerine 1.3g, 1,2-hexylene glycol 0.4g, 1,2-pentanediol, beta glucan, arginine, 1,3-Butanediol 4g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungus are carriedGet thing, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene first groundThat ammonium, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Blank group: 1,3-BDO 7g, betaine 5g, 1,2-pentanediol 3g, saualane 3g, poly-twoMethylsiloxane 3g, cetostearyl alcohol 2.5g, glycerine 2g, sucrose stearate 1g, sucrose distearate1g, isononyl isononanoate 0.6g, 1,2-hexylene glycol 0.7g, two (lauramide glutamine) Sodium lysinate0.05g, two-bis-many acyl groups of glycerine adipate ester-20.5g, pungent glycol 0.075g, PEG-45 stearate0.3g, beta glucan 0.0015g, Sensiva SC50 0.2g, tocopherol 0.1g, arginine 0.2g, poly-thirdOlefin(e) acid 0.2g, hydrolyzed vegetable protein 0.0025, atriphos 0.0025g, sodium chondroitin sulfate 0.0025g,Xanthans 0.05g, hydrolecithin 0.05g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g,Denatonium Benzoate 0.00002g.
Preparation method: (1) water intaking 62g, glycerine 1g, hydrolecithin, 1,3-BDO 3.5g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.05g, 1,2-hexylene glycol 0.35g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, sucrose stearate, sucrose two hardResin acid ester, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 stearate, fertilityPhenol 0.05g, adds oil phase pot, is heated to 65-70 DEG C, stirs, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 9g, glycerine 1g, 1,2-hexylene glycol 0.35g, 1,2-pentanediol, beta glucan, arginine, 1,3-fourthGlycol 3.5g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, platinum powder, natrium citricum, lemonAcid, Denatonium Benzoate, continue to stir, and is cooled to room temperature; Filling, to obtain final product.
Demonstration test 1: according to test one screening test, measure the Mai Laning value of different groups.
Result of the test: in table 2.
The Mai Laning value of the different emulsions of table 2 relatively
| Test group | Mai Laning value (a.u.) |
| Blank group | 477.9±1.1 |
| Test 1 group | 309.8±1.0*** |
| Test 2 groups | 304.1±1.4*** |
| Test 3 groups | 312.4±0.9*** |
Note: with relatively * * P < 0.01 of blank group, * * * P < 0.001.
Demonstration test 2: Mai Laning assay
The quantitative approach of Mai Laning is by following procedure operation: get skin after above-mentioned test, skin is shelled with tweezersFrom rear, insert the 1.0%SDS solution (containing 10mMTris-HCl, 0.05mMEDTA, pH6.8) of 450 μ LAfter the fragmentation of middle enforcement ultrasonic, add the pronase e solution 20 μ L of 5mg/mL, under 45 DEG C of conditions, heat12 hours. At the 500mMNa that adds 50 μ L2CO330%H with 10 μ L2O2Be placed on 80 DEG C of conditionsUnder heat 30 minutes. After cooling, add the chloroform of 100 μ L: methyl alcohol (2:1) mixed liquor is stirred,After centrifugation in 10 minutes, get its supernatant 100 μ L spectrometers and carry out the measurement of wavelength while being 405nm. SimultaneouslyUtilize synthetic Mai Laning (SIGMA) to carry out same measurement and production standard curve, foundation as standard sampleCalibration curve carries out quantitatively the contained Mai Laning in skin histology.
Result of the test: in table 3.
Table 3 Mai Laning content quantitative result
Note: with relatively * * P < 0.01 of blank group.
Conclusion (of pressure testing): above-mentioned test shows, emulsion of the present invention has the effect of good check melanin.
Three, stability test
Test 1 group: 1,3-BDO 7g, betaine 5g, 1,2-pentanediol 3g, saualane 3g, poly-Dimethyl siloxane 3g, cetostearyl alcohol 2.5g, glycerine 2g, sucrose stearate 1g, the acid of sucrose distearylEster 1g, isononyl isononanoate 0.6g, 1,2-hexylene glycol 0.7g, two (lauramide glutamine) lysineSodium 0.05g, two-bis-many acyl groups of glycerine adipate ester-20.5g, pungent glycol 0.075g, PEG-45 stearic acidEster 0.3g, beta glucan 0.0015g, Sensiva SC50 0.2g, tocopherol 0.1g, arginine 0.2g, poly-Acrylic acid 0.2g, hydrolyzed vegetable protein 0.0025, atriphos 0.0025g, sodium chondroitin sulfate 0.0025g,Xanthans 0.05g, hydrolecithin 0.05g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g,Denatonium Benzoate 0.00002g, glycyrrhiza glabra root extract 2g, Queensland nut seed oil 1g, halogen worm extract0.0001g, dried tremella extract 0.05g, fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 62g, glycerine 1g, hydrolecithin, 1,3-BDO 3.5g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.05g, 1,2-hexylene glycol 0.35g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.05g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 9g, glycerine 1g, 1,2-hexylene glycol 0.35g, 1,2-pentanediol, beta glucan, arginine, 1,3-Butanediol 3.5g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungusExtract, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene firstThat ammonium of ground, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Test 2 groups: 1,3-BDO 7g, betaine 5g, 1,2-pentanediol 3g, saualane 3g, poly-Dimethyl siloxane 3g, cetostearyl alcohol 2.5g, glycerine 2g, sucrose stearate 1g, the acid of sucrose distearylEster 1g, isononyl isononanoate 0.6g, 1,2-hexylene glycol 0.7g, two (lauramide glutamine) lysineSodium 0.05g, two-bis-many acyl groups of glycerine adipate ester-20.5g, pungent glycol 0.075g, PEG-45 stearic acidEster 0.3g, beta glucan 0.0015g, Sensiva SC50 0.2g, tocopherol 0.1g, arginine 0.2g, poly-Acrylic acid 0.2g, hydrolyzed vegetable protein 0.0025, atriphos 0.0025g, sodium chondroitin sulfate 0.0025g,Xanthans 0.05g, hydrolecithin 0.05g, platinum powder 0.0000002g, Denatonium Benzoate 0.00002g, lightFruit licorice root extract 2g, Queensland nut seed oil 1g, halogen worm extract 0.0001g, dried tremella extract 0.05g,Fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 62g, glycerine 1g, hydrolecithin, 1,3-BDO 3.5g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.05g, 1,2-hexylene glycol 0.35g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.05g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 9g, glycerine 1g, 1,2-hexylene glycol 0.35g, 1,2-pentanediol, beta glucan, arginine, 1,3-Butanediol 3.5g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungusExtract, platinum powder, fragrant citrus berry extract, glycyrrhiza glabra root extract, Denatonium Benzoate, continue to stir allEven, be cooled to room temperature; Filling, to obtain final product.
Test method: get emulsion, be placed in 40 DEG C and deposit 24h, deposit 24h in room temperature, then in-5 DEG CDeposit 24h, circulate successively 3 times, observe and whether have layering, oil slick, color and luster whether to change.
Conclusion (of pressure testing): in table 4.
Table 4 stability test result
| Group | Whether layering | Whether oil slick | Whether color and luster changes |
| Test 1 group | No | No | No |
| Test 2 groups | Have | Have | No |
Conclusion (of pressure testing): when not adding in emulsion after citric acid and natrium citricum, emulsion after cold cycling,Produce layering and oil slick phenomenon, do not produce such phenomenon and test 1 group, absolutely prove emulsion of the present inventionPrescription stability is better.
Preparation Example
Embodiment 1
1,3-BDO 6g, betaine 4g, 1,2-pentanediol 2g, saualane 2g, poly dimethyl silicaAlkane 2g, cetostearyl alcohol 2g, glycerine 1.5g, sucrose stearate 0.5g, sucrose distearate 0.5g,Isononyl isononanoate 0.5g, 1,2-hexylene glycol 0.6g, two (lauramide glutamine) Sodium lysinate 0.04g,Two-bis-many acyl groups of glycerine adipate ester-20.4g, pungent glycol 0.07g, PEG-45 stearate 0.2g, β-Glucan 0.001g, Sensiva SC50 0.1g, tocopherol 0.05g, arginine 0.1g, polyacrylic acid 0.1g,Hydrolyzed vegetable protein 0.002g, atriphos 0.002g, sodium chondroitin sulfate 0.002g, xanthans 0.04g,Hydrolecithin 0.04g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g, benzene first groundThat ammonium 0.00002g, glycyrrhiza glabra root extract 1g, Queensland nut seed oil 0.5g, halogen worm extract 0.0001g,Dried tremella extract 0.04g, fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 55g, glycerine 0.7g, hydrolecithin, 1,3-BDO 3g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.02g, 1,2-hexylene glycol 0.3g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.03g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 5g, glycerine 0.8g, 1,2-hexylene glycol 0.3g, 1,2-pentanediol, beta glucan, arginine, 1,3-fourthGlycol 3g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungus extractThing, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene first ground thatAmmonium, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Embodiment 2
1,3-BDO 7g, betaine 5g, 1,2-pentanediol 3g, saualane 3g, poly dimethyl silicaAlkane 3g, cetostearyl alcohol 2.5g, glycerine 2g, sucrose stearate 1g, sucrose distearate 1g, differentN-nonanoic acid ester 0.6g in the different ninth of the ten Heavenly Stems, 1,2-hexylene glycol 0.7g, two (lauramide glutamine) Sodium lysinate 0.05g,Two-bis-many acyl groups of glycerine adipate ester-20.5g, pungent glycol 0.075g, PEG-45 stearate 0.3g, β-glucan 0.0015g, Sensiva SC50 0.2g, tocopherol 0.1g, arginine 0.2g, polyacrylic acid 0.2g,Hydrolyzed vegetable protein 0.0025, atriphos 0.0025g, sodium chondroitin sulfate 0.0025g, xanthans 0.05g,Hydrolecithin 0.05g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g, benzene first groundThat ammonium 0.00002g, glycyrrhiza glabra root extract 2g, Queensland nut seed oil 1g, halogen worm extract 0.0001g,Dried tremella extract 0.05g, fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 62g, glycerine 1g, hydrolecithin, 1,3-BDO 3.5g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.05g, 1,2-hexylene glycol 0.35g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.05g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 9g, glycerine 1g, 1,2-hexylene glycol 0.35g, 1,2-pentanediol, beta glucan, arginine, 1,3-fourthGlycol 3.5g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungus extractThing, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene first ground thatAmmonium, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Embodiment 3
1,3-BDO 8g, betaine 6g, 1,2-pentanediol 4g, saualane 4g, dimethyl silicone polymer 4g,Cetostearyl alcohol 3g, glycerine 2.5g, sucrose stearate 1.5g, sucrose distearate 1.5g, different n-nonanoic acid are differentThe ninth of the ten Heavenly Stems ester 0.7g, 1,2-hexylene glycol 0.8g, two (lauramide glutamine) Sodium lysinate 0.06g, two-bis-are sweetMany acyl groups of oil adipate ester-20.6g, pungent glycol 0.08g, PEG-45 stearate 0.4g, beta glucan0.002g, Sensiva SC50 0.3g, tocopherol 0.15g, arginine 0.3g, polyacrylic acid 0.3g, hydrolysis are plantedThing albumen 0.003g, atriphos 0.003g, sodium chondroitin sulfate 0.003g, xanthans 0.06g, hydrogenation ovumPhosphatidase 10 .06g, platinum powder 0.0000002g, natrium citricum 0.01g, citric acid 0.003g, Denatonium Benzoate 0.00002g,Glycyrrhiza glabra root extract 2g, Queensland nut seed oil 1g, halogen worm extract 0.0001g, dried tremella extract 0.05g,Fragrant citrus berry extract 0.000003g.
Preparation method: (1) water intaking 70g, glycerine 1.2g, hydrolecithin, 1,3-BDO 4g, betaine,Xanthans, polyacrylic acid, Sensiva SC50, tocopherol 0.07g, 1,2-hexylene glycol 0.4g, pungent glycol,Two (lauramide glutamine) Sodium lysinate, adds water pot, is heated to, after 65-70 DEG C, stir,In suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol 0.08g, add oil phase pot, is heated to 65-70 DEG C, stir, and suction vacuum breastIn change machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water 11g, glycerine 1.3g, 1,2-hexylene glycol 0.4g, 1,2-pentanediol, beta glucan, arginine, 1,3-Butanediol 4g, hydrolyzed vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, white fungus are carriedGet thing, platinum powder, natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, benzene first groundThat ammonium, continues to stir, and is cooled to room temperature; Filling, to obtain final product.
Preparation Example includes but not limited to above-mentioned.
Claims (6)
1. an emulsion, is characterized in that emulsion comprises glycyrrhiza glabra root extract, Queensland nut oil, halogenWorm extract, dried tremella extract, fragrant citrus berry extract, Sensiva SC50.
2. a kind of emulsion according to claim 1, wherein glycyrrhiza glabra root extract 1-3 weight portion,Queensland nut oil 0.5-1.5 weight portion, halogen worm extract 0.0001 weight portion, dried tremella extract 0.04-0.06Weight portion, fragrant citrus berry extract 0.000003 weight portion, Sensiva SC50 0.1-0.3 weight portion.
3. a kind of emulsion according to claim 1, emulsion comprises: 1,3-BDO, betaine, 1,2-pentanediol, saualane, dimethyl silicone polymer, cetostearyl alcohol, glycerine, sucrose stearate, sucroseDistearate, isononyl isononanoate, 1,2-hexylene glycol, two (lauramide glutamine) Sodium lysinate,Two-bis-many acyl groups of glycerine adipate ester-2, pungent glycol, PEG-45 stearate, beta glucan, ethyl hexylBase glycerol, tocopherol, arginine, polyacrylic acid, hydrolyzed vegetable protein, atriphos, chondroitin sulphurAcid sodium, xanthans, hydrolecithin, platinum powder, natrium citricum, citric acid, Denatonium Benzoate, licoriceExtract, Queensland nut oil, halogen worm extract, dried tremella extract, fragrant citrus berry extract.
4. a kind of emulsion according to claim 1, emulsion comprises: 1,3-BDO 6-8 weight portion,Betaine 4-6 weight portion, 1,2-pentanediol 2-4 weight portion, saualane 2-4 weight portion, poly dimethyl silicaAlkane 2-4 weight portion, cetostearyl alcohol 2-3 weight portion, glycerine 1.5-2.5 weight portion, sucrose stearate 0.5-1.5Weight portion, sucrose distearate 0.5-1.5 weight portion, isononyl isononanoate 0.5-0.7 weight portion, 1,2-Hexylene glycol 0.6-0.8 weight portion, two (lauramide glutamine) Sodium lysinate 0.04-0.06 weight portion, two-bis-many acyl groups of glycerine adipate ester-20.4-0.6 weight portions, pungent glycol 0.07-0.08 weight portion, PEG-45 are hardResin acid ester 0.2-0.4 weight portion, beta glucan 0.001-0.002 weight portion, Sensiva SC50 0.1-0.3 weighAmount part, tocopherol 0.05-0.15 weight portion, arginine 0.1-0.3 weight portion, polyacrylic acid 0.1-0.3 weightPart, hydrolyzed vegetable protein 0.002-0.003 weight portion, atriphos 0.002-0.003 weight portion, chondroitinSodium sulphate 0.002-0.003 weight portion, xanthans 0.04-0.06 weight portion, hydrolecithin 0.04-0.06 weighAmount part, platinum powder 0.0000002 weight portion, natrium citricum 0.01 weight portion, citric acid 0.003 weight portion, benzeneThat ammonium 0.00002 weight portion of first ground, glycyrrhiza glabra root extract 1-3 weight portion, Queensland nut seed oil 0.5-1.5Weight portion, halogen worm extract 0.0001 weight portion, dried tremella extract 0.04-0.06 weight portion, fragrant citrus fruit are extractedThing 0.000003 weight portion.
5. a kind of emulsion according to claim 4, is characterized in that the preparation method of emulsion is:
(1) water intaking, glycerine, hydrolecithin, 1,3-BDO, betaine, xanthans, polyacrylic acid,Sensiva SC50, tocopherol, 1,2-hexylene glycol, pungent glycol, two (lauramide glutamine) lysineSodium, adds water pot, is heated to, after 65-70 DEG C, stir, in suction vacuum emulsifying machine;
(2) get saualane, dimethyl silicone polymer, cetostearyl alcohol, Queensland nut seed oil, sucrose tristearinAcid esters, sucrose distearate, isononyl isononanoate, two-bis-many acyl groups of glycerine adipate ester-2, PEG-45 are hardResin acid ester, tocopherol, add oil phase pot, is heated to 65-70 DEG C, stirs, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, and 30 minutes, 1000rpm/ divided, and stops stirring, and is cooled to 40 DEG C;Add water, glycerine, 1,2-hexylene glycol, 1,2-pentanediol, beta glucan, arginine, 1,3-BDO, waterSeparate vegetable protein, atriphos, sodium chondroitin sulfate, halogen worm extract, dried tremella extract, platinum powder,Natrium citricum, fragrant citrus berry extract, glycyrrhiza glabra root extract, citric acid, Denatonium Benzoate, continue to stirMix evenly, be cooled to room temperature; Filling, to obtain final product.
6. according to a kind of emulsion described in claim 1-5 any one, it is characterized in that glycyrrhiza glabra root extractsThing, Queensland nut oil, halogen worm extract, dried tremella extract and fragrant citrus berry extract are being prepared skin-lightening cosmeticIn application.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510829840.3A CN105596273B (en) | 2015-11-24 | 2015-11-24 | Clear Virgin's milk liquid of a kind of Shu Run and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510829840.3A CN105596273B (en) | 2015-11-24 | 2015-11-24 | Clear Virgin's milk liquid of a kind of Shu Run and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105596273A true CN105596273A (en) | 2016-05-25 |
| CN105596273B CN105596273B (en) | 2017-03-29 |
Family
ID=55977011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510829840.3A Active CN105596273B (en) | 2015-11-24 | 2015-11-24 | Clear Virgin's milk liquid of a kind of Shu Run and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105596273B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107550745A (en) * | 2017-08-31 | 2018-01-09 | 北京明弘科贸有限责任公司 | A kind of anticorrosive composite and its application |
| CN108272644A (en) * | 2018-03-05 | 2018-07-13 | 广州市白云采妮化妆品厂 | A kind of microemulsion and preparation method thereof helping active matter uniformly penetrating |
| CN108743504A (en) * | 2018-07-26 | 2018-11-06 | 湖南慕她生物科技发展有限公司 | A kind of plant acid whitening freckle-removing cream and its production technology |
| CN111773151A (en) * | 2020-07-06 | 2020-10-16 | 广东职业技术学院 | Whitening and freckle-removing antioxidant emulsion and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406581A (en) * | 2011-11-28 | 2012-04-11 | 天津郁美净集团有限公司 | Skin protecting composite with function of tightening skin |
| CN104688666A (en) * | 2015-03-13 | 2015-06-10 | 石桂源 | Skin tendering regenerating mask with cordyceps sinensis and preparation method thereof |
-
2015
- 2015-11-24 CN CN201510829840.3A patent/CN105596273B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406581A (en) * | 2011-11-28 | 2012-04-11 | 天津郁美净集团有限公司 | Skin protecting composite with function of tightening skin |
| CN104688666A (en) * | 2015-03-13 | 2015-06-10 | 石桂源 | Skin tendering regenerating mask with cordyceps sinensis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 戴玉等: "《中医美容大全》", 31 December 1997 * |
| 罗祖良等人: ""光果甘草的研究进展"", 《中草药》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107550745A (en) * | 2017-08-31 | 2018-01-09 | 北京明弘科贸有限责任公司 | A kind of anticorrosive composite and its application |
| CN108272644A (en) * | 2018-03-05 | 2018-07-13 | 广州市白云采妮化妆品厂 | A kind of microemulsion and preparation method thereof helping active matter uniformly penetrating |
| CN108743504A (en) * | 2018-07-26 | 2018-11-06 | 湖南慕她生物科技发展有限公司 | A kind of plant acid whitening freckle-removing cream and its production technology |
| CN111773151A (en) * | 2020-07-06 | 2020-10-16 | 广东职业技术学院 | Whitening and freckle-removing antioxidant emulsion and preparation method thereof |
| CN111773151B (en) * | 2020-07-06 | 2023-01-10 | 广东职业技术学院 | Whitening and freckle-removing antioxidant emulsion and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105596273B (en) | 2017-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103284940B (en) | Saccharomycetes fermented traditional Chinese medicine composition, as well as preparation method and application thereof | |
| WO2015135313A1 (en) | Borojo skin care product and use thereof for natural moisturizing, anti-ageing, anti-uv, anti-anaphylaxis and whitening | |
| CN101849899B (en) | Chinese medicinal compound extract and cosmetics comprising same as active ingredient | |
| CN105381007B (en) | External medicine composition, preparation with white-skinned face function and its preparation method and application | |
| CN105534796B (en) | A kind of antiallergy toner containing Folium Artemisiae Argyi extract and preparation method thereof | |
| CN106176348A (en) | Topical skin composition and the method processing skin | |
| CN108403521A (en) | Topical skin composition and application thereof | |
| CN104027293A (en) | Whitening cosmetic and preparation method thereof | |
| CN109453087B (en) | Whitening skin-penetrating lotion, preparation method thereof and whitening cosmetic additive | |
| CN108210421A (en) | A kind of whitening mask liquid of the extract containing Magnolia binodii and preparation method thereof | |
| CN106456526A (en) | Cosmetic composition for skin whitening and wrinkle alleviation, containing, as active ingredients, white rose extract and gartanin derivative compound isolated therefrom | |
| CN108186503A (en) | A kind of whitening emulsion of the extract containing Magnolia binodii and preparation method thereof | |
| CN105596273A (en) | Soothing, moistening, brightening and whitening emulsion and preparation method thereof | |
| CN111419773B (en) | Plant extract composition for skin aging resistance and repair, application thereof and essence containing composition | |
| CN110433122A (en) | A kind of composition and its application in the skin care item for preparing light speckles, beautification and white | |
| KR20170137552A (en) | Composition for improving skin condition comprising herb extracts mixture | |
| CN110151619B (en) | Sunscreen composition containing multiple active substances | |
| CN111529427A (en) | Active polypeptide compound plant extract anti-aging repair composition, application and essence milk containing composition | |
| US20150182443A1 (en) | Traditional chinese medicine extract composition with whitening skin-care function adn its preparation method | |
| CN108670933B (en) | Skin care composition with moisturizing, whitening and anti-aging functions and application thereof | |
| CN105326779B (en) | A kind of whitening curry and preparation method thereof | |
| CN104434684B (en) | Shining bloom of a kind of new life comprising plant extracts and preparation method thereof | |
| CN103948529B (en) | A kind of cosmetic composition containing tomato pulp extract | |
| CN107049883A (en) | A kind of preparation method of sunflower seed extract and its application in cosmetics | |
| JP2006143670A (en) | Skin lotion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: Panyu District Hualong Town Guangzhou city Guangdong province 511434 Liu Wai Street No. 13 (No. 1 building) Patentee after: Hua An Tang biotech Group Co., Ltd. Address before: Panyu District Hualong Town Guangzhou city Guangdong province 511434 Liu Wai Street No. 13 (No. 1 building) Patentee before: City flower An Tang bio tech ltd, Guangzhou |
|
| CP01 | Change in the name or title of a patent holder |