CN105596266A - Aromatic bacteriostatic mouth wash and preparation method thereof - Google Patents
Aromatic bacteriostatic mouth wash and preparation method thereof Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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Abstract
The invention discloses aromatic bacteriostatic mouth wash. The mouth wash is prepared from the following raw materials in parts by weight: 80-100 parts of water, 10-15 parts of ethanol, 10-12 parts of peony extract concentrate, 8-12 parts of radix scutellariae aqueous extract, 5-10 parts of coptis chinensis aqueous extract, 5-10 parts of uncaria 50wt%-ethanol aqueous extract, 6-8 parts of pericarpium arecae ethanol extract, 6-8 parts of humectant, 4-6 parts of hovenia dulcis thunb ethanol extract, 3-5 parts of hempleaf negundo chastetree leaf 50wt%-ethanol aqueous extract, 3-5 parts of sodium carboxymethylcellulose, 2-4 parts of inositol hexaphosphate, 0.4-0.6 part of dipotassium glycyrrhizinate, 0.3-0.5 part of cardanol, 0.1-0.2 part of a flavoring agent which is fructo-oligosaccharide and 0.1-0.2 part of a preservative. The aromatic bacteriostatic mouth wash has relatively strong effects of reducing oral microorganisms, inhibiting bacteria, diminishing inflammation and removing ozostomia, has a natural fragrance of peony, and has a strong effect for inhibiting escherichia coli and staphylococcus aureus. The mouth wash has an inhibition rate of over 85 percent on escherichia coli and staphylococcus aureus, and can be used safely for a long time.
Description
Technical field
The present invention relates to commodity manufacturing technology field, specifically a kind of fragrant bacteriostatic mouthwash and preparation method thereof.
Background technology
Along with social development, people's life, work, activity description have also increased a lot, often need to carry out social activity,Negotiate, report the work, the various activities that need communication such as amusement, affection exchange. If oneself have halitosis or due toSmoke, drinking causes oral cavity to have peculiar smell, will have influence on people's normal social activity.
Routine is brushed teeth and is merely able to remove the bacterial plaque (proximal surface can only go 30% bacterial plaque) of facing 40-50%, for removing soft group of oral cavityKnitting surperficial bacterial plaque substantially incompetent is power. And the mouthwash each position of human mouth deeply comprises the difficult gingival edge contacting of toothbrushAnd between teeth space, be the measure of a kind of well auxiliary control bacterial plaque. Oneself indispensable oral cavity in becoming people life of mouthwashCleaning supplies have advantages of easy to usely compared with toothpaste, are the favorable substitutes of toothpaste, be loss of tooth old man,The optimal selection that odontopathy patient's oral hygiene that the child that can not brush teeth and being impatient at brushes teeth ensures. In recent years, along with peopleThe continuous enhancing of health perception, more and more higher to the requirement of mouthwash, except also auxiliary some mouth diseases of prevention that clean the teeth.
Oral peculiar smell, (claiming again " implication ", is a kind of serious illness that endangers to be commonly called as halitosis. According to statistics up to 80-90%'sHalitosis is derived from microbial metabolism in oral cavity, and the generation of halitosis is the mistake that the corrupt protein substrate of oral microorganism produces smell substanceJourney. Halitosis can make people closely associate, and affects normal interpersonal feelings and exchanges, and makes us very worried. Research is at present recognizedFor particularly tooth event leaf beautiful jade monad (Pg) of intraoral gram-negative anaerobic bacteria, middle general Salmonella (Pi) and Fusobacterium nucleatum(Fn) can utilize protein, half skin propylhomoserin and methionine to produce a large amount of volatile sulfur compounds (VSCS), mainly comprise hydrogen sulfide,Methyl mercaptan, dimethylsulphide, dimethyl disulphide etc., thus form oral peculiar smell.
Existing mouthwash key component is essence, surfactant, fluoride, strontium chloride, alcohol and water etc., can cleanOral cavity, caries prevention and periodontitis etc. There is cool mouthfeel. Mouthwash has deep or light two kinds, and dense dilutes rear use with water, lightCan directly gargle. Extract separation, the antibacterial mouthwash of Chinese medicine of acquisition by thering is active ingredient in the Chinese medicine of antibacterial actionAlso be a good selection in mouthwash.
Summary of the invention
The object of the present invention is to provide a kind of can fresh breath, fragrant bacteriostatic mouthwash and preparation side thereof that germicidal efficiency is highMethod, to solve the problem proposing in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: water 80-100 part, ethanol 10-15 part, peonyExtract concentrated solution 10-12 part, yellow Cen water extract 8-12 part, coptis water extract 5-10 part, yncaria stem with hooks 50wt% ethanol water extractionGet thing 5-10 part, shell of areca nut ethanol extract 6-8 part, NMF 6-8 part, long-pending Dulcis ethanol extract 4-6 part, Vitex negundo var cannabifoliaLeaf 50wt% ethanol water extract 3-5 part, complete sodium carboxymethylcellulose pyce 3-5 part, inositol hexaphosphate 2-4 part, glycyrrhizic acid twoPotassium 0.4-0.6 part, anacardol 0.3-0.5 part, flavouring 0.1-0.2 part, anticorrisive agent 0.1-0.2 part.
As the further scheme of the present invention: described fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: water 85-95Part, ethanol 11-14 part, peony extract concentrated solution 10.5-11.5 part, yellow Cen water extract 9-11 part, coptis water extract6-9 part, yncaria stem with hooks 50wt% ethanol water extract 6-9 part, shell of areca nut ethanol extract 6.5-7.5 part, NMF 6.5-7.5 part,Amass Dulcis ethanol extract 4.5-5.5 part, leaf of negundo chastetree 50wt% ethanol water extract 3.5-4.5 part, complete sodium carboxymethylcellulose pyce3.5-4.5 part, inositol hexaphosphate 2.5-3.5 part, dipotassium glycyrrhizinate 0.45-0.55 part, anacardol 0.35-0.45 part, flavoringAgent 0.12-0.18 part, anticorrisive agent 0.12-0.18 part.
As the further scheme of the present invention: described fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: 90 parts, water,12 parts of ethanol, 11 parts of peony extract concentrated solutions, 10 parts of yellow Cen water extracts, 8 parts of coptis water extracts, yncaria stem with hooks 50wt%8 parts of ethanol water extracts, 7 parts of shell of areca nut ethanol extracts, 7 parts of NMFs, 5 parts of long-pending Dulcis ethanol extracts, Vitex negundo var cannabifolia4 parts of leaf 50wt% ethanol water extracts, complete 4 parts of sodium carboxymethylcellulose pyces, 3 parts of inositol hexaphosphates, dipotassium glycyrrhizinate 0.5Part, 0.4 part of anacardol, 0.15 part of flavouring, 0.15 part of anticorrisive agent.
As further scheme of the present invention: described flavouring is FOS.
The preparation method of described fragrant bacteriostatic mouthwash, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 50-70 DEG C, lixiviate feed liquidWeight ratio is 1:6-10, and extraction time is 2-4h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and HuangConnect water extract;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, added absolute ethyl alcohol to heat lixiviate after pulverizing, extraction temperature is50-60 DEG C, lixiviate feed liquid weight ratio is 1:10-14, extraction time is 3-5h, centrifugal after lixiviate, dense after supernatant is collectedContracting is shell of areca nut ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate respectively with 50wt% ethanol water, extraction temperature is55-65 DEG C, lixiviate feed liquid weight ratio is 1:6-8, and extraction time is 3-5h, and centrifugation after lixiviate, after collecting supernatantConcentrated, be yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 60-80min for the first time, and 20-40min for the second time, subtractsPressing the pressure extracting is 70-90mbar, and the temperature that decompression is extracted is 30-50 DEG C, and reduced pressure concentration after extracting liquid filtering, obtains closeDegree is 1.1-1.3g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract,Shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce,Alcohol six phosphates and dipotassium glycyrrhizinate are added in ethanol, stir after 10-20min, add water, NMF, flesh anacardol,Flavouring and anticorrisive agent, then stir ageing 40-60min after 20-30min, obtain mouthwash finished product after cooling.
Compared with prior art, the invention has the beneficial effects as follows:
The present invention not only has stronger reduction oral microorganism ability, degerming anti-inflammatory and the effect except halitosis, and has maleThe natural fragrance of red flower, has very strong inhibitory action to Escherichia coli and staphylococcus aureus, to pressing down of above-mentioned bacterial classificationRate processed all more than 85%, safety, can be used for a long time.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the technical scheme of this patent is described in more detail.
Embodiment 1
A kind of fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: 80 parts, water, 10 parts of ethanol, peony extract10 parts of concentrates, 8 parts of yellow Cen water extracts, 5 parts of coptis water extracts, 5 parts of yncaria stem with hooks 50wt% ethanol water extracts, large abdomen6 parts of skin ethanol extracts, 6 parts of NMFs, 4 parts of long-pending Dulcis ethanol extracts, leaf of negundo chastetree 50wt% ethanol water extract 3Part, complete 3 parts of sodium carboxymethylcellulose pyces, 2 parts of inositol hexaphosphates, 0.4 part of dipotassium glycyrrhizinate, 0.3 part of anacardol, oligomeric0.1 part, fructose, 0.1 part of anticorrisive agent.
The preparation method of described fragrant bacteriostatic mouthwash, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 50 DEG C, lixiviate feed liquid weightAmount is than being 1:6, and extraction time is 2h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and coptis water extractionThing;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, added absolute ethyl alcohol to heat lixiviate after pulverizing, extraction temperature is50 DEG C, lixiviate feed liquid weight ratio is 1:10, and extraction time is 3h, centrifugal after lixiviate, concentrated after supernatant is collected, for greatlyAbdomen skin ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate respectively with 50wt% ethanol water, extraction temperature is55 DEG C, lixiviate feed liquid weight ratio is 1:6, and extraction time is 3h, and centrifugation after lixiviate is concentrated after supernatant is collected,For yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 60min for the first time, and 20min for the second time, decompression is extractedPressure be 70mbar, decompression extract temperature be 30 DEG C, reduced pressure concentration after extracting liquid filtering, obtaining density is 1.1g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract,Shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce,Alcohol six phosphates and dipotassium glycyrrhizinate are added in ethanol, stir after 10min, add water, NMF, flesh anacardol, lowFructooligosaccharides and anticorrisive agent, then stir ageing 40min after 20min, obtain mouthwash finished product after cooling.
Embodiment 2
A kind of fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: 85 parts, water, 11 parts of ethanol, peony extract10.5 parts of concentrates, 9 parts of yellow Cen water extracts, 6 parts of coptis water extracts, 6 parts of yncaria stem with hooks 50wt% ethanol water extracts, large abdomen6.5 parts of skin ethanol extracts, 6.5 parts of NMFs, 4.5 parts of long-pending Dulcis ethanol extracts, leaf of negundo chastetree 50wt% ethanol water extraction are got3.5 parts of things, complete 3.5 parts of sodium carboxymethylcellulose pyces, 2.5 parts of inositol hexaphosphates, 0.45 part of dipotassium glycyrrhizinate, anacardol 0.35Part, 0.12 part of FOS, 0.12 part of anticorrisive agent.
The preparation method of described fragrant bacteriostatic mouthwash, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 55 DEG C, lixiviate feed liquid weightAmount is than being 1:7, and extraction time is 2.5h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and coptis waterExtract;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, added absolute ethyl alcohol to heat lixiviate after pulverizing, extraction temperature is52 DEG C, lixiviate feed liquid weight ratio is 1:11, and extraction time is 3.5h, centrifugal after lixiviate, concentrated after supernatant is collected, forShell of areca nut ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate respectively with 50wt% ethanol water, extraction temperature is58 DEG C, lixiviate feed liquid weight ratio is 1:6.5, and extraction time is 3.5h, and centrifugation after lixiviate is concentrated after supernatant is collected,For yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 65min for the first time, and 25min for the second time, decompression is extractedPressure be 75mbar, decompression extract temperature be 35 DEG C, reduced pressure concentration after extracting liquid filtering, obtaining density is 1.15g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract,Shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce,Alcohol six phosphates and dipotassium glycyrrhizinate are added in ethanol, stir after 12min, add water, NMF, flesh anacardol, lowFructooligosaccharides and anticorrisive agent, then stir ageing 45min after 22min, obtain mouthwash finished product after cooling.
Embodiment 3
A kind of fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: 90 parts, water, 12 parts of ethanol, peony extract11 parts of concentrates, 10 parts of yellow Cen water extracts, 8 parts of coptis water extracts, 8 parts of yncaria stem with hooks 50wt% ethanol water extracts, large abdomen7 parts of skin ethanol extracts, 7 parts of NMFs, 5 parts of long-pending Dulcis ethanol extracts, leaf of negundo chastetree 50wt% ethanol water extract 4Part, complete 4 parts of sodium carboxymethylcellulose pyces, 3 parts of inositol hexaphosphates, 0.5 part of dipotassium glycyrrhizinate, 0.4 part of anacardol, oligomeric0.15 part, fructose, 0.15 part of anticorrisive agent.
The preparation method of described fragrant bacteriostatic mouthwash, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 60 DEG C, lixiviate feed liquid weightAmount is than being 1:8, and extraction time is 3h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and coptis water extractionThing;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, added absolute ethyl alcohol to heat lixiviate after pulverizing, extraction temperature is55 DEG C, lixiviate feed liquid weight ratio is 1:12, and extraction time is 4h, centrifugal after lixiviate, concentrated after supernatant is collected, for greatlyAbdomen skin ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate respectively with 50wt% ethanol water, extraction temperature is60 DEG C, lixiviate feed liquid weight ratio is 1:7, and extraction time is 4h, and centrifugation after lixiviate is concentrated after supernatant is collected,For yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 70min for the first time, and 30min for the second time, decompression is extractedPressure be 80mbar, decompression extract temperature be 40 DEG C, reduced pressure concentration after extracting liquid filtering, obtaining density is 1.2g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract,Shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce,Alcohol six phosphates and dipotassium glycyrrhizinate are added in ethanol, stir after 15min, add water, NMF, flesh anacardol, lowFructooligosaccharides and anticorrisive agent, then stir ageing 50min after 25min, obtain mouthwash finished product after cooling.
Embodiment 4
A kind of fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: 95 parts, water, 14 parts of ethanol, peony extract11.5 parts of concentrates, 11 parts of yellow Cen water extracts, 9 parts of coptis water extracts, 9 parts of yncaria stem with hooks 50wt% ethanol water extracts, large7.5 parts of abdomen skin ethanol extracts, 7.5 parts of NMFs, 5.5 parts of long-pending Dulcis ethanol extracts, leaf of negundo chastetree 50wt% ethanol water extractionGet 4.5 parts of things, complete 4.5 parts of sodium carboxymethylcellulose pyces, 3.5 parts of inositol hexaphosphates, 0.55 part of dipotassium glycyrrhizinate, anacardol0.45 part, 0.18 part of FOS, 0.18 part of anticorrisive agent.
The preparation method of described fragrant bacteriostatic mouthwash, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 65 DEG C, lixiviate feed liquid weightAmount is than being 1:9, and extraction time is 3.5h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and coptis waterExtract;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, added absolute ethyl alcohol to heat lixiviate after pulverizing, extraction temperature is58 DEG C, lixiviate feed liquid weight ratio is 1:13, and extraction time is 4.5h, centrifugal after lixiviate, concentrated after supernatant is collected, forShell of areca nut ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate respectively with 50wt% ethanol water, extraction temperature is62 DEG C, lixiviate feed liquid weight ratio is 1:7.5, and extraction time is 4.5h, and centrifugation after lixiviate is concentrated after supernatant is collected,For yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 75min for the first time, and 35min for the second time, decompression is extractedPressure be 85mbar, decompression extract temperature be 45 DEG C, reduced pressure concentration after extracting liquid filtering, obtaining density is 1.25g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract,Shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce,Alcohol six phosphates and dipotassium glycyrrhizinate are added in ethanol, stir after 18min, add water, NMF, flesh anacardol, lowFructooligosaccharides and anticorrisive agent, then stir ageing 55min after 28min, obtain mouthwash finished product after cooling.
Embodiment 5
A kind of fragrant bacteriostatic mouthwash, comprises according to the raw material of weight portion: 100 parts, water, 15 parts of ethanol, peony are extracted12 parts of thing concentrates, 12 parts of yellow Cen water extracts, 10 parts of coptis water extracts, 10 parts of yncaria stem with hooks 50wt% ethanol water extracts,8 parts of shell of areca nut ethanol extracts, 8 parts of NMFs, 6 parts of long-pending Dulcis ethanol extracts, leaf of negundo chastetree 50wt% ethanol water extraction are got5 parts of things, complete 5 parts of sodium carboxymethylcellulose pyces, 4 parts of inositol hexaphosphates, 0.6 part of dipotassium glycyrrhizinate, 0.5 part of anacardol,0.2 part of FOS, 0.2 part of anticorrisive agent.
The preparation method of described fragrant bacteriostatic mouthwash, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 70 DEG C, lixiviate feed liquid weightAmount is than being 1:10, and extraction time is 4h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and coptis water extractionThing;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, added absolute ethyl alcohol to heat lixiviate after pulverizing, extraction temperature is60 DEG C, lixiviate feed liquid weight ratio is 1:14, and extraction time is 5h, centrifugal after lixiviate, concentrated after supernatant is collected, for greatlyAbdomen skin ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate respectively with 50wt% ethanol water, extraction temperature is65 DEG C, lixiviate feed liquid weight ratio is 1:8, and extraction time is 5h, and centrifugation after lixiviate is concentrated after supernatant is collected,For yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 80min for the first time, and 40min for the second time, decompression is extractedPressure be 90mbar, decompression extract temperature be 50 DEG C, reduced pressure concentration after extracting liquid filtering, obtaining density is 1.3g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract,Shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce,Alcohol six phosphates and dipotassium glycyrrhizinate are added in ethanol, stir after 20min, add water, NMF, flesh anacardol, lowFructooligosaccharides and anticorrisive agent, then stir ageing 60min after 30min, obtain mouthwash finished product after cooling.
The present invention not only has stronger reduction oral microorganism ability, degerming anti-inflammatory and the effect except halitosis, and has maleThe natural fragrance of red flower, has very strong inhibitory action to Escherichia coli and staphylococcus aureus, to pressing down of above-mentioned bacterial classificationRate processed all more than 85%, safety, can be used for a long time.
Above the preferred embodiments of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment,In the ken that those of ordinary skill in the art possesses, can also under the prerequisite that does not depart from this patent aim, make eachPlant and change.
Claims (5)
1. a fragrant bacteriostatic mouthwash, it is characterized in that, raw material according to weight portion comprises: water 80-100 part, ethanol 10-15 part, peony extract concentrated solution 10-12 part, yellow Cen water extract 8-12 part, coptis water extract 5-10 part, yncaria stem with hooks 50wt% ethanol water extract 5-10 part, shell of areca nut ethanol extract 6-8 part, NMF 6-8 part, long-pending Dulcis ethanol extract 4-6 part, leaf of negundo chastetree 50wt% ethanol water extract 3-5 part, complete sodium carboxymethylcellulose pyce 3-5 part, inositol hexaphosphate 2-4 part, dipotassium glycyrrhizinate 0.4-0.6 part, anacardol 0.3-0.5 part, flavouring 0.1-0.2 part, anticorrisive agent 0.1-0.2 part.
2. fragrant bacteriostatic mouthwash according to claim 1, it is characterized in that, raw material according to weight portion comprises: water 85-95 part, ethanol 11-14 part, peony extract concentrated solution 10.5-11.5 part, yellow Cen water extract 9-11 part, coptis water extract 6-9 part, yncaria stem with hooks 50wt% ethanol water extract 6-9 part, shell of areca nut ethanol extract 6.5-7.5 part, NMF 6.5-7.5 part, long-pending Dulcis ethanol extract 4.5-5.5 part, leaf of negundo chastetree 50wt% ethanol water extract 3.5-4.5 part, complete sodium carboxymethylcellulose pyce 3.5-4.5 part, inositol hexaphosphate 2.5-3.5 part, dipotassium glycyrrhizinate 0.45-0.55 part, anacardol 0.35-0.45 part, flavouring 0.12-0.18 part, anticorrisive agent 0.12-0.18 part.
3. fragrant bacteriostatic mouthwash according to claim 1, it is characterized in that, comprise according to the raw material of weight portion: 90 parts, water, 12 parts of ethanol, 11 parts of peony extract concentrated solutions, 10 parts of yellow Cen water extracts, 8 parts of coptis water extracts, 8 parts of yncaria stem with hooks 50wt% ethanol water extracts, 7 parts of shell of areca nut ethanol extracts, 7 parts of NMFs, 5 parts of long-pending Dulcis ethanol extracts, 4 parts of leaf of negundo chastetree 50wt% ethanol water extracts, complete 4 parts of sodium carboxymethylcellulose pyces, 3 parts of inositol hexaphosphates, 0.5 part of dipotassium glycyrrhizinate, 0.4 part of anacardol, 0.15 part of flavouring, 0.15 part of anticorrisive agent.
4. according to the arbitrary described fragrant bacteriostatic mouthwash of claim 1-3, it is characterized in that, described flavouring is FOS.
5. a preparation method for the fragrant bacteriostatic mouthwash as described in as arbitrary in claim 1-3, is characterized in that, concrete steps are as follows:
(1) take each raw material according to weight portion;
(2) yellow Cen and the coptis are smashed to pieces respectively, smashed to pieces the rear hot water lixiviate of using, when lixiviate, temperature is 50-70 DEG C, and lixiviate feed liquid weight ratio is 1:6-10, and extraction time is 2-4h, centrifugal after lixiviate, concentrated after collection supernatant, is yellow Cen water extract and coptis water extract;
(3) shell of areca nut and long-pending Dulcis are separately pulverized, after pulverizing, add absolute ethyl alcohol to heat lixiviate, extraction temperature is 50-60 DEG C, lixiviate feed liquid weight ratio is 1:10-14, extraction time is 3-5h, centrifugal after lixiviate, concentrated after supernatant is collected, be shell of areca nut ethanol extract and long-pending chess piece ethanol extract;
(4) after yncaria stem with hooks and leaf of negundo chastetree pulverizing, heat lixiviate with 50wt% ethanol water respectively, extraction temperature is 55-65 DEG C, lixiviate feed liquid weight ratio is 1:6-8, extraction time is 3-5h, centrifugation after lixiviate, concentrated after supernatant is collected, be yncaria stem with hooks 50wt% ethanol water extract and leaf of negundo chastetree 50wt% ethanol water extract;
(5), by peony alcohol immersion, decompression extracts twice, 60-80min for the first time, and 20-40min for the second time, the pressure that decompression is extracted is 70-90mbar, the temperature that decompression is extracted is 30-50 DEG C, reduced pressure concentration after extracting liquid filtering, obtaining density is 1.1-1.3g/cm3Peony extract concentrated solution;
(6) by peony extract concentrated solution, yellow Cen water extract, coptis water extract, yncaria stem with hooks 50wt% ethanol water extract, shell of areca nut ethanol extract, long-pending Dulcis ethanol extract, leaf of negundo chastetree 50wt% ethanol water extract, complete sodium carboxymethylcellulose pyce, alcohol six phosphates and dipotassium glycyrrhizinate and be added in ethanol, stir after 10-20min, add water, NMF, flesh anacardol, flavouring and anticorrisive agent, stir again ageing 40-60min after 20-30min, obtain mouthwash finished product after cooling.
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| CN107714569A (en) * | 2017-12-07 | 2018-02-23 | 威海职业学院 | A kind of preparation method of fragrant plant mouthwash |
| CN112754971A (en) * | 2021-03-24 | 2021-05-07 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition and preparation method and application thereof |
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| CN105030597A (en) * | 2015-07-15 | 2015-11-11 | 江苏奇力康皮肤药业有限公司 | Chinese herbal antibacterial mouthwash and preparation method thereof |
| CN105030579A (en) * | 2015-06-26 | 2015-11-11 | 江苏奇力康皮肤药业有限公司 | Fragrant vomit-stopping mouth wash and preparation method thereof |
| CN105106043A (en) * | 2015-07-16 | 2015-12-02 | 山东省分析测试中心 | Peony flower-containing anti-inflammation and deodorization fragrant mouthwash and preparation method thereof |
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| CN105030579A (en) * | 2015-06-26 | 2015-11-11 | 江苏奇力康皮肤药业有限公司 | Fragrant vomit-stopping mouth wash and preparation method thereof |
| CN105030597A (en) * | 2015-07-15 | 2015-11-11 | 江苏奇力康皮肤药业有限公司 | Chinese herbal antibacterial mouthwash and preparation method thereof |
| CN105106043A (en) * | 2015-07-16 | 2015-12-02 | 山东省分析测试中心 | Peony flower-containing anti-inflammation and deodorization fragrant mouthwash and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107714569A (en) * | 2017-12-07 | 2018-02-23 | 威海职业学院 | A kind of preparation method of fragrant plant mouthwash |
| CN112754971A (en) * | 2021-03-24 | 2021-05-07 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition and preparation method and application thereof |
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Application publication date: 20160525 |