CN105595015A - Preparation method of coated isoacid - Google Patents
Preparation method of coated isoacid Download PDFInfo
- Publication number
- CN105595015A CN105595015A CN201510529936.8A CN201510529936A CN105595015A CN 105595015 A CN105595015 A CN 105595015A CN 201510529936 A CN201510529936 A CN 201510529936A CN 105595015 A CN105595015 A CN 105595015A
- Authority
- CN
- China
- Prior art keywords
- acid
- dystopy
- coating
- preparation
- isoacid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention provides a preparation method of coated isoacid. The method comprises the steps of: S1. mixing isoacid monomers 2-methylbutyric acid, isobutyric acid, isovaleric acid and valeric acid evenly according to a proportion of 20-25:30-37.5:12.5-15:25-30 to obtain isoacid, then adding white carbon black to conduct mixed adsorption for 20-30min to obtain a mixture A; S2. mixing the mixture A obtained in S1 with potato starch and sodium lignosulfonate in a ratio of 88-92:6-8:2-4 to prepare isoacid pellets; S3. preparing a 1-3% acrylic resin IV solution; S4. preparing a 1-3% sodium ethyl cellulose solution; and S5. coating the isoacid pellets by means of fluidized bed bottom spraying. By performing coating treatment on isoacid, the method provided by the invention covers up the odor of isoacid, and is beneficial to application of isoacid in animal feed adding. The method has the advantages of simplicity, high yield, low production cost, and large scale industrial production, and the prepared product is more beneficial to adding into animal daily diet.
Description
Technical field
The present invention relates to coating field, be specifically related to the preparation method of a kind of coating peculiar smell acid.
Background technology
Dystopy acid is propping up of producing by branched-amino acid metabolic in animal microorganism sweatChain fatty acid, mainly comprises 2-Methyl Butyric Acid, isobutyric acid, isovaleric acid and valeric acid, is specialIn the organic acid preparation of adults.
In animal gastrointestinal tract, a large amount of microorganisms in perch, affects animal to nutrients in daily rationThe digestion of matter and absorption. In ruminant tumor gastric, it is micro-that these microbiological anaerobic fermentations are synthesizedBioprotein (MCP) can be animal 40%～60% of protein requirement is provided, the waving of generationThe property sent out aliphatic acid (VFA) can be animal provides 70%～80% of energy requirement. And it is blind pigIn intestines and colon, the volatile fatty acid (VFA) that microorganism fermentation fiber produces can be growthGrowing and fattening pigs provide 5%～30% of its energy demand, can be higher for sow.
A large amount of researchs show, dystopy acid has material impact to the fiber degradation of animal gastrointestinal tract.Research shows, dystopy acid is alimentary canal cellulose-decomposing bacteria normal growth and movable required chemical combinationThing, can increase the quantity of cellulose-decomposing bacteria, improves the digestion of intestines and stomach bacterium to plant cell wallAbility, thereby the digestibility of raising fiber feedstuff. Bryant and Doetsch (1955) are in vitroIn lumen fermentation test, show, add isobutyric acid, 2-Methyl Butyric Acid and isovaleric acid mixture and can urgeEnter the growth of the thread bacillus of anaerobic product butanedioic acid in rumen fluid. Allison etc. (1958) andHungate (1963) thinks, other important cellulose-decomposing bacterias are (as yellow Ruminococcus and whiteRuminococcus) growth also need branched chain fatty acid.
In addition, dystopy acid not only can be used as the special dietary material of cellulose decomposing bacteria, and rightIn intestines and stomach, microbial growth and microprotein synthetic has general facilitation. DystopyAcid can weaken the catabolism of its precusor amino acids in breast tissue, and superfluous branched-chain amino acid canFor biosynthesis or the participation other biological synthetic reaction of nonessential amino acid, and then make micro-lifeThe synthetic increase of thing albumen, increases nitrogen retention, improves the output of milk. Liu Qiang etc. (2006) researchShow, add after isobutyric acid in daily ration, in urine, the discharge rate of purine derivative increases, and shows dayIn grain, add isobutyric acid and can obviously increase microbial nitrogen supply. Li Hongyu etc. (2006) grindStudy carefully and show, in daily ration, add isobutyric acid and reduced cud NH3-N concentration, illustrate that isobutyric acid canPromote the utilization of microorganism to NH3-N, increase MCP synthetic.
Therefore, in animal diets, add dystopy acid and be conducive to the degraded of fiber and microproteinSynthetic, the raising of the production performance to animal has positive effect, but due to dystopy acid gasTaste is larger, and in actual applications, dystopy acid generally all needs with carrier dilution or is processed into calciumAfter salt, cover smell.
Summary of the invention
For the problem of dystopy acid special odor, the object of the invention is to design and utilize coating wallCarry out the acid of coating dystopy, cover the smell of dystopy acid. The inventive method is simple, and productive rate is high, producesCost is low, can large-scale industrial production, the product of preparation is more conducive to add in animal diets.
Particularly, the invention provides the preparation method of the compound dystopy acid of a kind of coating, it comprise withLower step:
S1, the acid of outfit peculiar smell: by the each monomer 2-Methyl Butyric Acid of dystopy acid, isobutyric acid, isoamylAcid and valeric acid mix according to the ratio of 20-25: 30-37.5: 12.5-15: 25-30To dystopy acid, then add white carbon mixing and absorption 20-30min to obtain mixture A, whereinThe mass ratio of white carbon and dystopy acid is 0.5-1.5: 2-2.48;
S2, prepare peculiar smell acid micropill: by the mixture A obtaining in S1 and farina,Sodium lignin sulfonate mixes according to the ratio of 88-92: 6-8: 2-4, adds a certain amount of water, utilizesMicropill granulating system is prepared into the peculiar smell acid micropill that diameter is 500-1500 μ m;
The preparation of S3, acrylic resin IV wall material solution: take 10-30g acrylic resin IVAdd 1000mL95% alcoholic solution, stir it is dissolved, be mixed with the acrylic acid of 1-3%Resin IV solution;
The preparation of S4, ethyl cellulose sodium wall material solution: take 10-30g ethyl cellulose sodiumAdd 1000mL95% alcoholic solution, stir it is dissolved, be mixed with the ethyl fibre of 1-3%Tie up plain sodium solution;
S5, utilize spray mode coating dystopy acid micropill at the bottom of fluid bed: first by core dystopy acid micropillPack in paint booth, then regulate atomizing pressure and EAT to make dystopy acid micropill be fluidisation stateAnd reach needed temperature, then by peristaltic pump, wall material solution is passed through to paint booth spray gun sprayingOn core and make coating dystopy acid micropill, coating dystopy acid micropill diameter is 1000-1800μm。
Preferably, the ratio 25 of 2-Methyl Butyric Acid, isobutyric acid, isovaleric acid and valeric acid in S1:37.5∶12.5∶25。
Preferably, the mass ratio of white carbon and dystopy acid is 1: 2.48.
Preferably, in S1, the ratio of mixture A, farina and sodium lignin sulfonate is90∶8∶2。
Preferably, in S1, peculiar smell acid is 30min with the time of white carbon mixing and absorption.
Preferably, in S3, the concentration of acrylic resin IV solution is 3%.
Preferably, in S4, the concentration of ethyl cellulose sodium solution is 3%.
The present invention, by dystopy acid is carried out to coating processing, has covered the smell of dystopy acid, is beneficial toThe application of dystopy acid in animal feed adds. The inventive method is simple, and productive rate is high, is produced intoThis is low, can large-scale industrial production, the product of preparation is more conducive to add in animal diets.
Brief description of the drawings
Fig. 1 is process chart of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing and detailed description of the invention, structure of the present invention and operation principle are doneFurther explain:
Particularly, the invention provides the preparation method of the compound dystopy acid of a kind of coating, as Fig. 1 instituteShow, it comprises the following steps:
S1, the acid of outfit peculiar smell: by the each monomer 2-Methyl Butyric Acid of dystopy acid, isobutyric acid, isoamylAcid and valeric acid mix according to the ratio of 20-25: 30-37.5: 12.5-15: 25-30To dystopy acid, then add white carbon mixing and absorption 20-30min to obtain mixture A, whereinThe mass ratio of white carbon and dystopy acid is 0.5-1.5: 2-2.48;
S2, prepare peculiar smell acid micropill: by the mixture A obtaining in S1 and farina,Sodium lignin sulfonate mixes according to the ratio of 88-92: 6-8: 2-4, adds a certain amount of water, utilizesMicropill granulating system is prepared into the peculiar smell acid micropill that diameter is 500-1500 μ m;
The preparation of S3, acrylic resin IV wall material solution: take 10-30g acrylic resin IVAdd 1000mL95% alcoholic solution, stir it is dissolved, be mixed with the acrylic acid of 1-3%Resin IV solution;
The preparation of S4, ethyl cellulose sodium wall material solution: take 10-30g ethyl cellulose sodiumAdd 1000mL95% alcoholic solution, stir it is dissolved, be mixed with the ethyl fibre of 1-3%Tie up plain sodium solution;
S5, utilize spray mode coating dystopy acid micropill at the bottom of fluid bed: first by core dystopy acid micropillPack in paint booth, then regulate atomizing pressure and EAT to make dystopy acid micropill be fluidisation stateAnd reach needed temperature, then by peristaltic pump, wall material solution is passed through to paint booth spray gun sprayingOn core and make coating dystopy acid product, coating dystopy acid diameter is 1000-1800 μ m.
Below in conjunction with specific embodiment, the present invention will be further described:
Embodiment 1:
According to 25: 37.5: 12.5: 25 ratio, get monomer 2-Methyl Butyric Acid, isobutyric acid,Isovaleric acid and valeric acid mix, and are mixed with the solution of 1000ml; Take white carbon mixed 200G, closes absorption 30min with the dystopy acid that mixes of 496ml; Take after the acid of absorption dystopyWhite carbon 180g, farina 16g, sodium lignin sulfonate 4g, adds distillationWater 10ml mixes, then to make diameter with micropill granulating system be 1000 μ m micropills;Take respectively 30g acrylic resin IV and ethyl cellulose and add respectively 1000mL95% wineEssence solution, stirs it is dissolved, and is mixed with 3% acrylic resin IV solution and ethyl celluloseCellulose solution; The dystopy acid micropill having made with spray mode coating at the bottom of fluid bed, the coating obtaining is differentPosition acid gas taste is little, and diameter is 1200 μ m.
Embodiment 2:
According to 25: 37.5: 12.5: 25 ratio, get monomer 2-Methyl Butyric Acid, isobutyric acid,Isovaleric acid and valeric acid mix, and are mixed with the solution of 1000ml; Take white carbon mixed 300G, closes absorption 30min with the dystopy acid that mixes of 496ml; Take after the acid of absorption dystopyWhite carbon 180g, farina 16g, sodium lignin sulfonate 4g, adds distillationWater 12ml mixes, then to make diameter with micropill granulating system be 1300 μ m micropills;Take respectively 30g acrylic resin IV and ethyl cellulose and add respectively 1000mL95% wineEssence solution, stirs it is dissolved, and is mixed with 3% acrylic resin IV solution and ethyl celluloseCellulose solution; Dystopy acid micropill is packed in paint booth, then regulate atomizing pressure and EATMake dystopy acid micropill be fluidisation state and reach needed temperature. Then by peristaltic pump by molten wall materialLiquid is made coating dystopy acid product, the bag obtaining by paint booth spray gun spraying in core materialFilm dystopy acid gas taste is little, and diameter is 1600 μ m.
Finally it should be noted that: above-described each embodiment is only for illustrating technology of the present inventionScheme, is not intended to limit; Although the present invention has been carried out to detailed saying with reference to previous embodimentBright, those of ordinary skill in the art is to be understood that: it still can be remembered previous embodimentThe technical scheme of carrying is modified, or to wherein partly or entirely technical characterictic be equal to and replaceChange; And these amendments or replacement do not make the essence of appropriate technical solution depart from the each reality of the present inventionExecute the scope of routine technical scheme.
Claims (7)
1. a preparation method for coating dystopy acid, is characterized in that: it comprises the following steps:
S1, the acid of outfit peculiar smell: the each monomer 2-Methyl Butyric Acid of dystopy acid, isobutyric acid, isovaleric acid and valeric acid are pressedMix and obtain dystopy acid according to the ratio of 20-25: 30-37.5: 12.5-15: 25-30, then add whiteCarbon black mixing and absorption 20-30min obtains mixture A, and wherein the mass ratio of white carbon and dystopy acid is0.5-1.5∶2-2.48；
S2, prepare peculiar smell acid micropill: by the mixture A obtaining in S1 and farina, lignin sulfonic acidSodium mixes according to the ratio of 88-92: 6-8: 2-4, adds a certain amount of water, utilizes micropill granulating system to be prepared intoDiameter is the peculiar smell acid micropill of 500-1500 μ m;
The preparation of S3, acrylic resin IV wall material solution: take 10-30g acrylic resin IV and add 1000ML95% alcoholic solution, stirs it is dissolved, and is mixed with the acrylic resin IV solution of 1-3%;
The preparation of S4, ethyl cellulose sodium wall material solution: take 10-30g ethyl cellulose sodium and add 1000mL95% alcoholic solution, stirs it is dissolved, and is mixed with the ethyl cellulose sodium solution of 1-3%;
S5, utilize spray mode coating dystopy acid micropill at the bottom of fluid bed: first pack core dystopy acid micropill into applicationIndoor, then regulate atomizing pressure and EAT to make dystopy acid micropill be fluidisation state and reach needed temperatureDegree, then on core makes coating dystopy acid by wall material solution by paint booth spray gun spraying by peristaltic pumpMicropill, coating dystopy acid micropill diameter is 1000-1800 μ m.
2. the preparation method of coating dystopy according to claim 1 acid, is characterized in that: 2-in S1The ratio of methylbutanoic acid, isobutyric acid, isovaleric acid and valeric acid 25: 37.5: 12.5: 25.
3. the preparation method of coating dystopy according to claim 1 acid, is characterized in that: white carbon withThe mass ratio of dystopy acid is 1: 2.48.
4. the preparation method of coating dystopy according to claim 1 acid, is characterized in that: mixed in S1The ratio of compound A, farina and sodium lignin sulfonate is 90: 8: 2.
5. the preparation method of coating dystopy according to claim 1 acid, is characterized in that: different in S1Taste acid is 30min with the time of white carbon mixing and absorption.
6. the preparation method of coating dystopy according to claim 1 acid, is characterized in that: in S3 thirdThe concentration of olefin(e) acid resin IV solution is 3%.
7. the preparation method of coating dystopy according to claim 1 acid, is characterized in that: second in S4The concentration of base sodium cellulosate solution is 3%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510529936.8A CN105595015A (en) | 2015-08-27 | 2015-08-27 | Preparation method of coated isoacid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510529936.8A CN105595015A (en) | 2015-08-27 | 2015-08-27 | Preparation method of coated isoacid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105595015A true CN105595015A (en) | 2016-05-25 |
Family
ID=55975823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510529936.8A Pending CN105595015A (en) | 2015-08-27 | 2015-08-27 | Preparation method of coated isoacid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105595015A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106107055A (en) * | 2016-06-30 | 2016-11-16 | 湖南晶天科技实业有限公司 | A kind of feed additive enteric coating butanoic acid and preparation method and a kind of feedstuff |
| WO2018049494A1 (en) * | 2016-09-15 | 2018-03-22 | Do Val Heloise | Process for producing encapsulated microparticles for ruminants, uses and resulting products |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1864521A (en) * | 2005-05-17 | 2006-11-22 | 珠海天翼医药技术开发有限公司 | A method for preparing sustained-release micro-pellet feeding enzyme |
| CN101664113A (en) * | 2009-09-08 | 2010-03-10 | 北京资源亚太动物药品有限公司 | Enteric microcapsule of garlic essential oil and production method thereof |
| CN102326714A (en) * | 2011-09-28 | 2012-01-25 | 山东农业大学 | Ruminant rumen by-pass coating material and application thereof in choline coating |
| CN102511665A (en) * | 2011-12-29 | 2012-06-27 | 青岛蔚蓝生物集团有限公司 | Phytase-coated pellets and preparation method thereof |
| CN104041706A (en) * | 2014-06-05 | 2014-09-17 | 四川农业大学 | Isoacids additive for promoting synthesis of rumen microorganism protein of ruminants |
| CN105166396A (en) * | 2014-06-13 | 2015-12-23 | 泰兴瑞泰化工有限公司 | Acidifying agent for forage addition, and preparation method thereof |
-
2015
- 2015-08-27 CN CN201510529936.8A patent/CN105595015A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1864521A (en) * | 2005-05-17 | 2006-11-22 | 珠海天翼医药技术开发有限公司 | A method for preparing sustained-release micro-pellet feeding enzyme |
| CN101664113A (en) * | 2009-09-08 | 2010-03-10 | 北京资源亚太动物药品有限公司 | Enteric microcapsule of garlic essential oil and production method thereof |
| CN102326714A (en) * | 2011-09-28 | 2012-01-25 | 山东农业大学 | Ruminant rumen by-pass coating material and application thereof in choline coating |
| CN102511665A (en) * | 2011-12-29 | 2012-06-27 | 青岛蔚蓝生物集团有限公司 | Phytase-coated pellets and preparation method thereof |
| CN104041706A (en) * | 2014-06-05 | 2014-09-17 | 四川农业大学 | Isoacids additive for promoting synthesis of rumen microorganism protein of ruminants |
| CN105166396A (en) * | 2014-06-13 | 2015-12-23 | 泰兴瑞泰化工有限公司 | Acidifying agent for forage addition, and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106107055A (en) * | 2016-06-30 | 2016-11-16 | 湖南晶天科技实业有限公司 | A kind of feed additive enteric coating butanoic acid and preparation method and a kind of feedstuff |
| WO2018049494A1 (en) * | 2016-09-15 | 2018-03-22 | Do Val Heloise | Process for producing encapsulated microparticles for ruminants, uses and resulting products |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102178092B (en) | Method for preparing high-moisture fermented granular feed for poultry | |
| CN101366449B (en) | Microorganism vitamin premixed material and preparation method | |
| CN101683125A (en) | Method for preparing biological fermentation feed for pigs | |
| CN106260504B (en) | Method for producing microbial fermentation wet feed by using beer yeast paste | |
| CN104664169B (en) | A kind of ruminant feed bio-enhancer and preparation method thereof | |
| CN102370049A (en) | Chicken manure fermented feed | |
| CN107279462A (en) | The method of chrysanthemum meal fermenting and producing aquatic products livestock and poultry active peptide powder | |
| WO2015090205A1 (en) | Method for producing biological feed additive by utilizing cassava residue and alcohol waste mash | |
| CN102630844A (en) | Preparation method of biological feed for ruminants | |
| CN104489334A (en) | Zinc-rich microbial feed additive for dairy cow and preparation method of zinc-rich microbial feed additive | |
| CN103549163B (en) | Cherry Valley meat duck medium-stage feed | |
| CN103583462B (en) | Cherry valley meat duckbreeding method | |
| CN104642749A (en) | Composite micro-ecological preparation for promoting animal digestion and absorption | |
| CN105595015A (en) | Preparation method of coated isoacid | |
| CN108703264A (en) | A kind of feed and preparation method thereof reducing Roll road discharge of methane | |
| CN112342256A (en) | Method for preparing feed-grade fructo-oligosaccharide by taking molasses as raw material | |
| CN107439793A (en) | The production method of feeding biologic ferment calcium | |
| CN104664052B (en) | Functional living being feed production technology | |
| CN104839441A (en) | Lactobacillus straw powder biological complete feed and preparation method thereof | |
| CN109170150A (en) | The method for preparing feed using microorganism | |
| CN102669445A (en) | Method for producing chelated coated sustained-release protein feed | |
| CN108991228A (en) | A kind of method and its application of the compound organic trace element of biosynthesis | |
| CN103125752A (en) | Biochemical increasing milk preparation of dairy cow | |
| CN112890011A (en) | Production and preparation method of small peptide powder for feed | |
| CN112790273A (en) | Method for recovering L-lactic acid fermentation thallus and continuously producing fermented feed |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20170106 Address after: 430312 Hankou, Hubei Evergreen Garden Road, No. 68, Applicant after: Wuhan Polytechnic University Address before: 430024 Wuhan, Hubei, East and West Lake District Evergreen Garden Street, West Central special -9-201, No. 1 Applicant before: Zhao Shengjun |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160525 |