CN105497649A - Preparation method of Tibetan medicine for treating enteritis of children - Google Patents
Preparation method of Tibetan medicine for treating enteritis of children Download PDFInfo
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- CN105497649A CN105497649A CN201610041053.7A CN201610041053A CN105497649A CN 105497649 A CN105497649 A CN 105497649A CN 201610041053 A CN201610041053 A CN 201610041053A CN 105497649 A CN105497649 A CN 105497649A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract
The invention discloses a preparation method of a Tibetan medicine for treating enteritis of children. The Tibetan medicine is prepared by preparing an active ingredient from holarrhena antidysenteriaca Wall.ex A.DC, berberis kansuensis Schneid, bezoar, artificial bezoar, style and stigma of saffron crocus, safflower and tabasheer according to a certain weight ratio by adopting a mixing and grinding method or a water extraction and alcohol precipitation method or an alcohol extraction and water precipitation method and can be prepared into any common oral dosage form. The Tibetan medicine has the functions of clearing away heat and toxic materials, diminishing inflammation and relieving itching and eliminating yellow water diseases and is used for treating the diseases, such as urinary tract infection, skin diseases, pneumonia, hepatitis, cholecystitis and enteritis of children.
Description
Technical field
The present invention relates to a kind of preparation method for the treatment of child's enteritis Tibetan medicine, belong to Tibetan medicine field.
Background technology
China existing 0 ~ 14 years old child about 300,000,000, the problem of department of pediatrics shortage of medical services and medicines is very serious.Be mainly manifested in children special-purpose medicine deficient, many use adult medicines.Therefore, there is tight demand in the Tibetan medicinal preparation of people to treatment child enteritis.
Up to now, any report about Tibetan medicinal composition of the present invention is not also found.The present inventor through repeatedly studying, and by a large amount of zoopery and clinical practice, finally have found Tibetan medicinal preparation of the treatment child enteritis of better curative effect and preparation method thereof, thus completes the present invention.
Summary of the invention
The object of the invention is just to provide a kind of preparation method of more effectively treating child's enteritis Tibetan medicine.
The present invention is a kind of Tibetan medicine; be be made up of active component or be made up of active component and pharmaceutically acceptable adjuvant, wherein said active component is made up of following bulk drugs: seed of Cortex Holarrhenae Antidysentericae, Radix Berberidis Amurensis, Calculus Bovis, artificial Calculus Bovis, Stigma Croci, Flos Carthami, Concretio Silicea Bambusae.
It has selected seed of Cortex Holarrhenae Antidysentericae, Radix Berberidis Amurensis, Calculus Bovis, artificial Calculus Bovis, Stigma Croci, Flos Carthami, Concretio Silicea Bambusae carry out combining as crude drug, and wherein (1) seed of Cortex Holarrhenae Antidysentericae is apocynaceae plant tellicherry bark HolarrhenaantidysentericaWall.exA.
DC. dry seed.There is heat clearing away, function of gallbladder promoting, effect of antidiarrheal.Sick for red bar, liver-gallbladder disease, gastrointestinal calentura, diarrhoea, dysentery.(2) Radix Berberidis Amurensis is skin in the drying of Berberidaceae plant kansu barberry bark BerbeiskansuensisSchneid..Nature and flavor are cool, bitter.Have place heat clearly, relieving heat toxin, holds back the function of yellow fluid; For epidemic disease, old calentura, grasserie, oculopathy; Control acute enteritis, dysentery, jaundice, pyretic arthralgia, pneumonia, conjunctivitis, carbuncle furuncle, metrorrhagia.Berberine has the pharmacological actions such as blood sugar lowering, antibacterial and immunosuppressive action.(3) Calculus Bovis is the dry cholelithiasis of bovid cattle BostaurusdomesticusGmelin.Have and clear away heart-fire, eliminating phlegm, have one's ideas straightened out, cool liver, endogenous wind stopping, effect of removing toxic substances.For calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.(4) artificial Calculus Bovis is made up of bilein, cholic acid, Hyodeoxycholic Acid, taurine, bilirubin, cholesterol, trace element etc.Have heat clearing away, removing toxic substances, reduces phlegm, effect of arresting convulsion.For the hot delirium of expectorant, in silence, children's is hot infantile convulsion suddenly, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle for coma.(5) Stigma Croci is the dry stigma of irides Stigma Croci CrocussativusL..There is blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, effect of resolving stagnation for tranquilization.For amenorrhea and mass in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is vexed, and palpitation with fear is gone mad.(6) Flos Carthami is the dried floral of feverfew Flos Carthami CarthamustinctoriusL..There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.(7) Concretio Silicea Bambusae is the dried block of juice in the bar such as grass Chinese textile bamboo BambusatextilisMcClure or schizostachyum chinense Rendle SchizostachyumchinenseRendle.There is clear heat and eliminate phlegm, effect of cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.These crude drug are combinationally used and makes each crude drug effect produce synergism, thus can effectively treat child's enteritis.
The consumption of Tibetan medicine active component of the present invention is also through inventor and gropes in a large number to sum up and draw, each crude drug consumption for all to have good therapeutic effect within the scope of following concrete weight proportion:
Seed of Cortex Holarrhenae Antidysentericae 147 ~ 441g, Radix Berberidis Amurensis 158 ~ 474g, Calculus Bovis 0.13 ~ 0.38g, artificial Calculus Bovis 209 ~ 627g, Stigma Croci 2.5 ~ 7.5g, Flos Carthami 170 ~ 508g, Concretio Silicea Bambusae 232 ~ 696g.
Be preferably: seed of Cortex Holarrhenae Antidysentericae 236 ~ 353g, Radix Berberidis Amurensis 253 ~ 379g, Calculus Bovis 0.2 ~ 0.3g, artificial Calculus Bovis 334 ~ 502g, Stigma Croci 4 ~ 6g, Flos Carthami 270 ~ 407g, Concretio Silicea Bambusae 370 ~ 557g.
More preferably: seed of Cortex Holarrhenae Antidysentericae 294g, Radix Berberidis Amurensis 316g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g.
Inventor is by a large amount of zoopery and clinical practice, and filter out the Tibetan medicine that said components makes treatment child enteritis, the direct synergism of various component, therapeutic effect is definite.
The preparation of Tibetan medicine active component of the present invention can be made by direct for the crude drug of above-mentioned consumption co-grinding; Also the crude drug of above-mentioned consumption can be adopted the conventional method of Chinese medicine preparation such as decoction and alcohol sedimentation technique or ethanol extract from water precipitation (see " pharmaceutics of Chinese drugs " 73rd ~ 74 pages of Cao Chunlin chief editor, Science and Technology of Shanghai publishing house publishes in November, 1986) to obtain.
The active component of Tibetan medicine of the present invention can add various customary adjuvant required when preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. with the method for Chinese medicinal of routine (see Cao Chunlin chief editor " pharmaceutics of Chinese drugs ", Science and Technology of Shanghai publishing house in November, 1986 publishes) be prepared into any one and commonly use peroral dosage form, as powder, pill, capsule, granule, tablet etc.
Tibetan medicine of the present invention has heat-clearing and toxic substances removing, anti-inflammatory anti-itch, effect of yellow fluid reducing.For urinary tract infection, dermatosis, pneumonia, hepatitis, cholecystitis, the diseases such as child's enteritis.
The usage and dosage of Tibetan medicine of the present invention is: oral; Be grown up a 1g, child 0.25g, 1 ~ 2 time on the one.
[detailed description of the invention]
Carrying out the preparation method setting forth Tibetan medicine of the present invention further by the following examples, all features disclosed in this description, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Arbitrary feature disclosed in this description, unless specifically stated otherwise, all can be replaced by other equivalences or the alternative features with similar object.That is, unless specifically stated otherwise, each feature is an example in a series of equivalence or similar characteristics.
The preparation of [embodiment 1] Tibetan medicine powder of the present invention:
Take seed of Cortex Holarrhenae Antidysentericae 294g, Radix Berberidis Amurensis 316g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g, be jointly ground into fine powder after mixing, mixing, subpackage, obtains powder.
The preparation of [embodiment 2] Tibetan medicine pill of the present invention:
Take seed of Cortex Holarrhenae Antidysentericae 441g, Radix Berberidis Amurensis 474g, Calculus Bovis 0.38g, artificial Calculus Bovis 627g, Stigma Croci 7.5g, Flos Carthami 508g, Concretio Silicea Bambusae 696g, be jointly ground into fine powder after mixing, mixing, with water pill, dry below 60 DEG C, polishing, packaging, obtains pill.
The preparation of [embodiment 3] Tibetan medicine granule of the present invention:
Take seed of Cortex Holarrhenae Antidysentericae 147g, Radix Berberidis Amurensis 158g, Calculus Bovis 0.13g, artificial Calculus Bovis 209g, Stigma Croci 2.5g, Flos Carthami 170g, Concretio Silicea Bambusae 232g, after mixing, be jointly ground into fine powder, mixing; add adjuvant and make granule, dry below 60 DEG C, granulate; subpackage, obtains granule.
The preparation of [embodiment 4] Tibetan medicine capsule of the present invention:
Take seed of Cortex Holarrhenae Antidysentericae 236g, Radix Berberidis Amurensis 253g, Calculus Bovis 0.2g, artificial Calculus Bovis 334g, Stigma Croci 4g, Flos Carthami 270g, Concretio Silicea Bambusae 370g, be jointly ground into fine powder after mixing, mixing, load gelatine capsule, subpackage, obtains capsule.
The preparation of [embodiment 5] Tibetan medicine tablet of the present invention:
Take seed of Cortex Holarrhenae Antidysentericae 353g, Radix Berberidis Amurensis 379g, Calculus Bovis 0.3g, artificial Calculus Bovis 502g, Stigma Croci 6g, Flos Carthami 407g, Concretio Silicea Bambusae 557g, after mixing, be jointly ground into fine powder, mixing; add adjuvant and make granule, dry below 60 DEG C, granulate; tabletting, subpackage, obtains tablet.
The foregoing is only the preferred embodiment of Tibetan medicine of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. treat the preparation method of child's enteritis Tibetan medicine for one kind, it is characterized in that comprising the following steps: that this Tibetan medicine is made up of active component or is made up of active component and pharmaceutically acceptable adjuvant, wherein said active component is made up of the crude drug of following concrete weight proportion: seed of Cortex Holarrhenae Antidysentericae 147 ~ 441g, Radix Berberidis Amurensis 158 ~ 474g, Calculus Bovis 0.13 ~ 0.38g, artificial Calculus Bovis 209 ~ 627g, Stigma Croci 2.5 ~ 7.5g, Flos Carthami 170 ~ 508g, Concretio Silicea Bambusae 232 ~ 696g; Mixing, adopts comminuting method or decoction and alcohol sedimentation technique or ethanol extract from water precipitation to make active component.
2. the preparation method of Tibetan medicine according to claim 1, wherein takes the crude drug of following concrete weight proportion: seed of Cortex Holarrhenae Antidysentericae 236 ~ 353g, Radix Berberidis Amurensis 253 ~ 379g, Calculus Bovis 0.2 ~ 0.3g, artificial Calculus Bovis 334 ~ 502g, Stigma Croci 4 ~ 6g, Flos Carthami 270 ~ 407g, Concretio Silicea Bambusae 370 ~ 557g.
3. the preparation method of Tibetan medicine according to claim 2, the crude drug wherein taking following concrete weight is made: seed of Cortex Holarrhenae Antidysentericae 294g, Radix Berberidis Amurensis 316g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g.
4. the preparation method of a kind of Tibetan medicine according to any one of claim 1-3, it also comprises the following steps: active component and pharmaceutically acceptable adjuvant to make powder, pill, granule, capsule or tablet.
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| CN201610041053.7A CN105497649A (en) | 2016-01-22 | 2016-01-22 | Preparation method of Tibetan medicine for treating enteritis of children |
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| CN201610041053.7A CN105497649A (en) | 2016-01-22 | 2016-01-22 | Preparation method of Tibetan medicine for treating enteritis of children |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105079344A (en) * | 2015-09-09 | 2015-11-25 | 白玛仁增 | Compound Tibetan medicine preparation for treating gastroenteritis, gastric ulcer, cholecystitis and icterohepatitis |
| CN105125766A (en) * | 2015-09-09 | 2015-12-09 | 白玛仁增 | Compound Tibetan medicine preparation for treating fatty liver and alcoholic liver, expelling gall bladder and intestine roundworms and detoxifying |
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2016
- 2016-01-22 CN CN201610041053.7A patent/CN105497649A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105079344A (en) * | 2015-09-09 | 2015-11-25 | 白玛仁增 | Compound Tibetan medicine preparation for treating gastroenteritis, gastric ulcer, cholecystitis and icterohepatitis |
| CN105125766A (en) * | 2015-09-09 | 2015-12-09 | 白玛仁增 | Compound Tibetan medicine preparation for treating fatty liver and alcoholic liver, expelling gall bladder and intestine roundworms and detoxifying |
Non-Patent Citations (2)
| Title |
|---|
| 土旦次仁等: "《中国医学百科全书 藏医学》", 30 November 1999, 上海科学技术出版社 * |
| 索朗顿珠等: "《藏汉合璧常用藏成药实用手册》", 31 December 2006, 民族出版社 * |
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