CN105497648A - Tibetan medicine for treating liver diseases of children - Google Patents

Tibetan medicine for treating liver diseases of children Download PDF

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Publication number
CN105497648A
CN105497648A CN201610041047.1A CN201610041047A CN105497648A CN 105497648 A CN105497648 A CN 105497648A CN 201610041047 A CN201610041047 A CN 201610041047A CN 105497648 A CN105497648 A CN 105497648A
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tibetan medicine
calculus bovis
diseases
children
active component
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久美彭措
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/413Gall bladder; Bile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Tibetan medicine for treating liver diseases of children. The Tibetan medicine is prepared from an active ingredient or the active ingredient and pharmaceutically acceptable auxiliary materials, wherein the active ingredient is prepared from herba swertiae chirayitae, herb of entire meconopsis, bezoar, artificial bezoar, style and stigma of saffron crocus, safflower and tabasheer according to a certain weight ratio. The Tibetan medicine can be prepared into any common oral dosage form. The Tibetan medicine has the functions of clearing heat and relieving a cough, diminishing inflammation and eliminating plagues and eliminating yellow water diseases and is used for treating heart diseases, liver diseases, skin diseases, liver diseases of children, and the like.

Description

A kind of Tibetan medicine for the treatment of child's hepatopathy
Technical field
The present invention relates to a kind of Tibetan medicine for the treatment of child's hepatopathy, belong to Tibetan medicine field.
Background technology
China existing 0 ~ 14 years old child about 300,000,000, the problem of department of pediatrics shortage of medical services and medicines is very serious.Be mainly manifested in children special-purpose medicine deficient, many use adult medicines.Therefore, there is tight demand in the Tibetan medicinal preparation of people to treatment child hepatopathy.
Up to now, any report about Tibetan medicinal composition of the present invention is not also found.The present inventor through repeatedly studying, and by a large amount of zoopery and clinical practice, finally have found Tibetan medicinal preparation of the treatment child hepatopathy of better curative effect and preparation method thereof, thus completes the present invention.
Summary of the invention
The object of the invention is just to provide a kind of Tibetan medicine of more effectively treating child's hepatopathy.
The present invention is a kind of Tibetan medicine; be be made up of active component or be made up of active component and pharmaceutically acceptable adjuvant, wherein said active component is made up of following bulk drugs: Indian Herba Swertiae bimaculatae, Herba meconopsis integrifoliae, Calculus Bovis, artificial Calculus Bovis, Stigma Croci, Flos Carthami, Concretio Silicea Bambusae.
It has selected Indian Herba Swertiae bimaculatae, Herba meconopsis integrifoliae, Calculus Bovis, artificial Calculus Bovis, Stigma Croci, Flos Carthami, Concretio Silicea Bambusae carry out combining as crude drug, and wherein (1) Indian Herba Swertiae bimaculatae is gentianaceae plant Indian Herba Swertiae bimaculatae Swertiachirayita (Roxb.exFlemi)
The dry herb of Karsten.There is liver heat removing function of gallbladder promoting, move back effect of all heat.For icterohepatitis, viral hepatitis and disorders of blood, gastropathy, brings down a fever, cathartic, and has tonic effect.(2) Herba meconopsis integrifoliae is bloodroot full edge Herba meconopsis integrifoliae Meconopsis
The dry herb of integrifolia (Maxim.) Franch. and Flos meconopsis quintuplinerviae MeconapsisquintuplinerviaRegel, Herba meconopsis integrifoliae Meconopsislancifolia (Fra-nch.) Franch. etc. that comes into leaves.There is heat clearing away, diuresis, antiinflammatory, effect of pain relieving.For pneumonia, hepatitis, the heat symptom-complex of liver and lung, edema.(3) Calculus Bovis is the dry cholelithiasis of bovid cattle BostaurusdomesticusGmelin.Have and clear away heart-fire, eliminating phlegm, have one's ideas straightened out, cool liver, endogenous wind stopping, effect of removing toxic substances.For calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.(4) artificial Calculus Bovis is made up of bilein, cholic acid, Hyodeoxycholic Acid, taurine, bilirubin, cholesterol, trace element etc.Have heat clearing away, removing toxic substances, reduces phlegm, effect of arresting convulsion.For the hot delirium of expectorant, in silence, children's is hot infantile convulsion suddenly, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle for coma.(5) Stigma Croci is the dry stigma of irides Stigma Croci CrocussativusL..There is blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, effect of resolving stagnation for tranquilization.For amenorrhea and mass in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is vexed, and palpitation with fear is gone mad.(6) Flos Carthami is the dried floral of feverfew Flos Carthami CarthamustinctoriusL..There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia , mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.(7) Concretio Silicea Bambusae is the dried block of juice in the bar such as grass Chinese textile bamboo BambusatextilisMcClure or schizostachyum chinense Rendle SchizostachyumchinenseRendle.There is clear heat and eliminate phlegm, effect of cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.These crude drug are combinationally used and makes each crude drug effect produce synergism, thus can effectively treat child's hepatopathy.
The consumption of Tibetan medicine active component of the present invention is also through inventor and gropes in a large number to sum up and draw, each crude drug consumption for all to have good therapeutic effect within the scope of following concrete weight proportion:
Indian Herba Swertiae bimaculatae 128 ~ 383g, Herba meconopsis integrifoliae 116 ~ 350g, Calculus Bovis 0.13 ~ 0.38g, artificial Calculus Bovis 209 ~ 627g, Stigma Croci 2.5 ~ 7.5g, Flos Carthami 170 ~ 508g, Concretio Silicea Bambusae 232 ~ 696g.
Be preferably: Indian Herba Swertiae bimaculatae 204 ~ 306g, Herba meconopsis integrifoliae 186 ~ 280g, Calculus Bovis 0.2 ~ 0.3g, artificial Calculus Bovis 334 ~ 502g, Stigma Croci 4 ~ 6g, Flos Carthami 270 ~ 407g, Concretio Silicea Bambusae 370 ~ 557g.
More preferably: Indian Herba Swertiae bimaculatae 255g, Herba meconopsis integrifoliae 233g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g.
Inventor is by a large amount of zoopery and clinical practice, and filter out the Tibetan medicine that said components makes treatment child hepatopathy, the direct synergism of various component, therapeutic effect is definite.
The preparation of Tibetan medicine active component of the present invention can be made by direct for the crude drug of above-mentioned consumption co-grinding; Also the crude drug of above-mentioned consumption can be adopted the conventional method of Chinese medicine preparation such as decoction and alcohol sedimentation technique or ethanol extract from water precipitation (see " pharmaceutics of Chinese drugs " 73rd ~ 74 pages of Cao Chunlin chief editor, Science and Technology of Shanghai publishing house publishes in November, 1986) to obtain.
The active component of Tibetan medicine of the present invention can add various customary adjuvant required when preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. with the method for Chinese medicinal of routine (see Cao Chunlin chief editor " pharmaceutics of Chinese drugs ", Science and Technology of Shanghai publishing house in November, 1986 publishes) be prepared into any one and commonly use peroral dosage form, as powder, pill, capsule, granule, tablet etc.
Tibetan medicine of the present invention has clearing and antitussive, and pestilence is killed in antiinflammatory, effect of yellow fluid reducing.For heart disease, hepatopathy, dermatosis, child's hepatopathy etc.
The usage and dosage of Tibetan medicine of the present invention is: oral; Be grown up a 1g, child 0.25g, 1 ~ 2 time on the one.
[detailed description of the invention]
Carrying out the preparation method setting forth Tibetan medicine of the present invention further by the following examples, all features disclosed in this description, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Arbitrary feature disclosed in this description, unless specifically stated otherwise, all can be replaced by other equivalences or the alternative features with similar object.That is, unless specifically stated otherwise, each feature is an example in a series of equivalence or similar characteristics.
The preparation of [embodiment 1] Tibetan medicine powder of the present invention:
Take Indian Herba Swertiae bimaculatae 255g, Herba meconopsis integrifoliae 233g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g, be jointly ground into fine powder after mixing, mixing, subpackage, obtains powder.
The preparation of [embodiment 2] Tibetan medicine pill of the present invention:
Take Indian Herba Swertiae bimaculatae 383g, Herba meconopsis integrifoliae 350g, Calculus Bovis 0.38g, artificial Calculus Bovis 627g, Stigma Croci 7.5g, Flos Carthami 508g, Concretio Silicea Bambusae 696g, after mixing, be jointly ground into fine powder, mixing; with water pill, dry below 60 DEG C, polishing; packaging, obtains pill.
The preparation of [embodiment 3] Tibetan medicine granule of the present invention:
Take Indian Herba Swertiae bimaculatae 128g, Herba meconopsis integrifoliae 116g, Calculus Bovis 0.13g, artificial Calculus Bovis 209g, Stigma Croci 2.5g, Flos Carthami 170g, Concretio Silicea Bambusae 232g, after mixing, be jointly ground into fine powder, mixing; add adjuvant and make granule, dry below 60 DEG C, granulate; subpackage, obtains granule.
The preparation of [embodiment 4] Tibetan medicine capsule of the present invention:
Take Indian Herba Swertiae bimaculatae 204g, Herba meconopsis integrifoliae 186g, Calculus Bovis 0.2g, artificial Calculus Bovis 334g, Stigma Croci 4g, Flos Carthami 270g, Concretio Silicea Bambusae 370g, be jointly ground into fine powder after mixing, mixing, load gelatine capsule, subpackage, obtains capsule.
The preparation of [embodiment 5] Tibetan medicine tablet of the present invention:
Take Indian Herba Swertiae bimaculatae 306g, Herba meconopsis integrifoliae 280g, Calculus Bovis 0.3g, artificial Calculus Bovis 502g, Stigma Croci 6g, Flos Carthami 407g, Concretio Silicea Bambusae 557g, after mixing, be jointly ground into fine powder, mixing; add adjuvant and make granule, dry below 60 DEG C, granulate; tabletting, subpackage, obtains tablet.
The foregoing is only the preferred embodiment of Tibetan medicine of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.

Claims (5)

1. treat the Tibetan medicine of child's hepatopathy for one kind; it is characterized in that it is made up of active component or is made up of active component and pharmaceutically acceptable adjuvant, wherein said active component is made up of the crude drug of following concrete weight proportion: Indian Herba Swertiae bimaculatae 128 ~ 383g, Herba meconopsis integrifoliae 116 ~ 350g, Calculus Bovis 0.13 ~ 0.38g, artificial Calculus Bovis 209 ~ 627g, Stigma Croci 2.5 ~ 7.5g, Flos Carthami 170 ~ 508g, Concretio Silicea Bambusae 232 ~ 696g.
2. Tibetan medicine according to claim 1, wherein said active component is made up of the crude drug of following concrete weight proportion: Indian Herba Swertiae bimaculatae 204 ~ 306g, Herba meconopsis integrifoliae 186 ~ 280g, Calculus Bovis 0.2 ~ 0.3g, artificial Calculus Bovis 334 ~ 502g, Stigma Croci 4 ~ 6g, Flos Carthami 270 ~ 407g, Concretio Silicea Bambusae 370 ~ 557g.
3. Tibetan medicine according to claim 2, wherein said active component is made up of the crude drug of following concrete weight: Indian Herba Swertiae bimaculatae 255g, Herba meconopsis integrifoliae 233g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g.
4. a kind of Tibetan medicine according to any one of claim 1-3, it is peroral dosage form.
5. Tibetan medicine according to claim 4, it is powder, pill, granule, capsule or tablet.
CN201610041047.1A 2016-01-22 2016-01-22 Tibetan medicine for treating liver diseases of children Pending CN105497648A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634159A (en) * 2003-12-30 2005-07-06 乡城县藏医院 Pharmaceutical composition, its preparation process and usage
CN102579870A (en) * 2012-02-28 2012-07-18 山东阿如拉药物研究开发有限公司 Traditional Tibetan medicine composition and preparation for treating liver diseases, and preparation method thereof
CN102579869A (en) * 2012-02-28 2012-07-18 山东阿如拉药物研究开发有限公司 Preparation method of traditional Tibetan medicine composition for treating liver diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634159A (en) * 2003-12-30 2005-07-06 乡城县藏医院 Pharmaceutical composition, its preparation process and usage
CN102579870A (en) * 2012-02-28 2012-07-18 山东阿如拉药物研究开发有限公司 Traditional Tibetan medicine composition and preparation for treating liver diseases, and preparation method thereof
CN102579869A (en) * 2012-02-28 2012-07-18 山东阿如拉药物研究开发有限公司 Preparation method of traditional Tibetan medicine composition for treating liver diseases

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