CN105477436A - Method for preparing Tibetan medicine for treating children nephrosis - Google Patents
Method for preparing Tibetan medicine for treating children nephrosis Download PDFInfo
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- CN105477436A CN105477436A CN201610041027.4A CN201610041027A CN105477436A CN 105477436 A CN105477436 A CN 105477436A CN 201610041027 A CN201610041027 A CN 201610041027A CN 105477436 A CN105477436 A CN 105477436A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a method for preparing a Tibetan medicine for treating children nephrosis. The Tibetan medicine is prepared from active components prepared from juniperus formosana Hayata, areca catechu, bezoar, calculus bovis factitius, crocus sativus, carthamus tinctorius and tabasheer according to a certain weight ratio by adopting a mixed smashing method, a water extraction and alcohol precipitation method or an alcohol extration and water precipitation method, and can be prepared into any commonly used internal taking dosage. The Tibetan medicine has the efficacies of diminishing inflammation, relieving internal heat or fever and inducing diuresis, and can be used for pneumonosis, hepatopathy, nephrosis, helminthiasis, skin inflammation, children nephrosis, anuresis and the like.
Description
Technical field
The present invention relates to a kind of preparation method for the treatment of Childhood Nephrotic Syndrome Tibetan medicine, belong to Tibetan medicine field.
Background technology
China existing 0 ~ 14 years old child about 300,000,000, the problem of department of pediatrics shortage of medical services and medicines is very serious.Be mainly manifested in children special-purpose medicine deficient, many use adult medicines.
Children Kidney Diseases mostly is chronic disease, and common drug has immunosuppressant, glucocorticoid, all kinds of blood pressure lowering, lipid lowerers etc., needs long-term prescription, but many without children special-purpose medicine, multiplex adult's medicine.
Childhood Nephrotic Syndrome is a chronic disease, treatment is a long-term system engineering, add the immunosuppressant such as hormone, cyclophosphamide that current medical circle selects and all there is obvious side effect, therefore, there is tight demand to the Tibetan medicinal preparation that curative effect better treats Childhood Nephrotic Syndrome in people.
Up to now, any report about Tibetan medicinal composition of the present invention is not also found.The present inventor through repeatedly studying, and by a large amount of zoopery and clinical practice, finally have found Tibetan medicinal preparation of the treatment Childhood Nephrotic Syndrome of better curative effect and preparation method thereof, thus completes the present invention.
Summary of the invention
The object of the invention is just to provide a kind of preparation method of more effectively treating Childhood Nephrotic Syndrome Tibetan medicine.
The present invention is a kind of Tibetan medicine; be be made up of active component or be made up of active component and pharmaceutically acceptable adjuvant, wherein said active component is made up of following bulk drugs: Juniperus oxycedrus, Semen Arecae, Calculus Bovis, artificial Calculus Bovis, Stigma Croci, Flos Carthami, Concretio Silicea Bambusae.
It has selected Juniperus oxycedrus, Semen Arecae, Calculus Bovis, artificial Calculus Bovis, Stigma Croci, Flos Carthami, Concretio Silicea Bambusae carry out combining as crude drug, and wherein (1) Juniperus oxycedrus is band leaf twig and the fruit of Cupressaceae plant Juniperus oxycedrus JuniperusformosanaHayata..There is effect of heat clearing away, the kidney invigorating.Cure mainly kidney-heat disease, the enuresis, hydrops, treat poison, the diseases such as anthrax.(2) Semen Arecae is the dry mature seed of babassu Semen Arecae ArecacatechuL..There is killing insect and eliminating accumulation, sending down the abnormal ascending QI, row water, effect of preventing the attack (or recurrence) of malaria.For cestode, ascarid, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria.(3) Calculus Bovis is the dry cholelithiasis of bovid cattle BostaurusdomesticusGmelin.Have and clear away heart-fire, eliminating phlegm, have one's ideas straightened out, cool liver, endogenous wind stopping, effect of removing toxic substances.For calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.(4) artificial Calculus Bovis is made up of bilein, cholic acid, Hyodeoxycholic Acid, taurine, bilirubin, cholesterol, trace element etc.Have heat clearing away, removing toxic substances, reduces phlegm, effect of arresting convulsion.For the hot delirium of expectorant, in silence, children's is hot infantile convulsion suddenly, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle for coma.(5) Stigma Croci is the dry stigma of irides Stigma Croci CrocussativusL..There is blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, effect of resolving stagnation for tranquilization.For amenorrhea and mass in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is vexed, and palpitation with fear is gone mad.(6) Flos Carthami is the dried floral of feverfew Flos Carthami CarthamustinctoriusL..There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.(7) Concretio Silicea Bambusae is the dried block of juice in the bar such as grass Chinese textile bamboo BambusatextilisMcClure or schizostachyum chinense Rendle SchizostachyumchinenseRendle.There is clear heat and eliminate phlegm, effect of cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.These crude drug are combinationally used and makes each crude drug effect produce synergism, thus effectively can treat Childhood Nephrotic Syndrome.
The consumption of Tibetan medicine active component of the present invention is also through inventor and gropes in a large number to sum up and draw, each crude drug consumption for all to have good therapeutic effect within the scope of following concrete weight proportion:
Juniperus oxycedrus 156 ~ 467g, Semen Arecae 187 ~ 561g, Calculus Bovis 0.13 ~ 0.38g, artificial Calculus Bovis 209 ~ 627g, Stigma Croci 2.5 ~ 7.5g, Flos Carthami 170 ~ 508g, Concretio Silicea Bambusae 232 ~ 696g.
Be preferably: Juniperus oxycedrus 249 ~ 373g, Semen Arecae 299 ~ 449g, Calculus Bovis 0.2 ~ 0.3g, artificial Calculus Bovis 334 ~ 502g, Stigma Croci 4 ~ 6g, Flos Carthami 270 ~ 407g, Concretio Silicea Bambusae 370 ~ 557g.
More preferably: Juniperus oxycedrus 311g, Semen Arecae 374g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g.
Inventor is by a large amount of zoopery and clinical practice, and filter out the Tibetan medicine that said components makes treatment Childhood Nephrotic Syndrome, the direct synergism of various component, therapeutic effect is definite.
The preparation of Tibetan medicine active component of the present invention can be made by direct for the crude drug of above-mentioned consumption co-grinding; Also the crude drug of above-mentioned consumption can be adopted the conventional method of Chinese medicine preparation such as decoction and alcohol sedimentation technique or ethanol extract from water precipitation (see " pharmaceutics of Chinese drugs " 73rd ~ 74 pages of Cao Chunlin chief editor, Science and Technology of Shanghai publishing house publishes in November, 1986) to obtain.
The active component of Tibetan medicine of the present invention can add various customary adjuvant required when preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. with the method for Chinese medicinal of routine (see Cao Chunlin chief editor " pharmaceutics of Chinese drugs ", Science and Technology of Shanghai publishing house in November, 1986 publishes) be prepared into any one and commonly use peroral dosage form, as powder, pill, capsule, granule, tablet etc.
Tibetan medicine of the present invention has antiinflammatory, removing toxic substances, effect of diuresis.For pneumonopathy, hepatopathy, nephropathy, vermination, scytitis, Childhood Nephrotic Syndrome, urine retention etc.
The usage and dosage of Tibetan medicine of the present invention is: oral; Be grown up a 1g, child 0.25g, 1 ~ 2 time on the one.
[detailed description of the invention]
Carrying out the preparation method setting forth Tibetan medicine of the present invention further by the following examples, all features disclosed in this description, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Arbitrary feature disclosed in this description, unless specifically stated otherwise, all can be replaced by other equivalences or the alternative features with similar object.That is, unless specifically stated otherwise, each feature is an example in a series of equivalence or similar characteristics.
The preparation of [embodiment 1] Tibetan medicine powder of the present invention:
Take Juniperus oxycedrus 311g, Semen Arecae 374g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g, be jointly ground into fine powder after mixing, mixing, subpackage, obtains powder.
The preparation of [embodiment 2] Tibetan medicine pill of the present invention:
Take Juniperus oxycedrus 467g, Semen Arecae 561g, Calculus Bovis 0.38g, artificial Calculus Bovis 627g, Stigma Croci 7.5g, Flos Carthami 508g, Concretio Silicea Bambusae 696g, be jointly ground into fine powder after mixing, mixing, with water pill, dry below 60 DEG C, polishing, packaging, obtains pill.
The preparation of [embodiment 3] Tibetan medicine granule of the present invention:
Take Juniperus oxycedrus 156g, Semen Arecae 187g, Calculus Bovis 0.13g, artificial Calculus Bovis 209g, Stigma Croci 2.5g, Flos Carthami 170g, Concretio Silicea Bambusae 232g, after mixing, be jointly ground into fine powder, mixing; add adjuvant and make granule, dry below 60 DEG C, granulate; subpackage, obtains granule.
The preparation of [embodiment 4] Tibetan medicine capsule of the present invention:
Take Juniperus oxycedrus 249g, Semen Arecae 299g, Calculus Bovis 0.2g, artificial Calculus Bovis 334g, Stigma Croci 4g, Flos Carthami 270g, Concretio Silicea Bambusae 370g, be jointly ground into fine powder after mixing, mixing, load gelatine capsule, subpackage, obtains capsule.
The preparation of [embodiment 5] Tibetan medicine tablet of the present invention:
Take Juniperus oxycedrus 373g, Semen Arecae 449g, Calculus Bovis 0.3g, artificial Calculus Bovis 502g, Stigma Croci 6g, Flos Carthami 407g, Concretio Silicea Bambusae 557g, after mixing, be jointly ground into fine powder, mixing; add adjuvant and make granule, dry below 60 DEG C, granulate; tabletting, subpackage, obtains tablet.
The foregoing is only the preferred embodiment of Tibetan medicine of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. treat the preparation method of Childhood Nephrotic Syndrome Tibetan medicine for one kind, it is characterized in that comprising the following steps: that this Tibetan medicine is made up of active component or is made up of active component and pharmaceutically acceptable adjuvant, wherein said active component is made up of the crude drug of following concrete weight proportion: Juniperus oxycedrus 156 ~ 467g, Semen Arecae 187 ~ 561g, Calculus Bovis 0.13 ~ 0.38g, artificial Calculus Bovis 209 ~ 627g, Stigma Croci 2.5 ~ 7.5g, Flos Carthami 170 ~ 508g, Concretio Silicea Bambusae 232 ~ 696g; Mixing, adopts comminuting method or decoction and alcohol sedimentation technique or ethanol extract from water precipitation to make active component.
2. the preparation method of Tibetan medicine according to claim 1, wherein takes the crude drug of following concrete weight proportion: Juniperus oxycedrus 249 ~ 373g, Semen Arecae 299 ~ 449g, Calculus Bovis 0.2 ~ 0.3g, artificial Calculus Bovis 334 ~ 502g, Stigma Croci 4 ~ 6g, Flos Carthami 270 ~ 407g, Concretio Silicea Bambusae 370 ~ 557g.
3. the preparation method of Tibetan medicine according to claim 2, the crude drug wherein taking following concrete weight is made: Juniperus oxycedrus 311g, Semen Arecae 374g, Calculus Bovis 0.25g, artificial Calculus Bovis 418g, Stigma Croci 5g, Flos Carthami 339g, Concretio Silicea Bambusae 464g.
4. the preparation method of a kind of Tibetan medicine according to any one of claim 1-3, it also comprises the following steps: active component and pharmaceutically acceptable adjuvant to make powder, pill, granule, capsule or tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610041027.4A CN105477436A (en) | 2016-01-22 | 2016-01-22 | Method for preparing Tibetan medicine for treating children nephrosis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610041027.4A CN105477436A (en) | 2016-01-22 | 2016-01-22 | Method for preparing Tibetan medicine for treating children nephrosis |
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| CN105477436A true CN105477436A (en) | 2016-04-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610041027.4A Pending CN105477436A (en) | 2016-01-22 | 2016-01-22 | Method for preparing Tibetan medicine for treating children nephrosis |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1356117A (en) * | 2001-01-11 | 2002-07-03 | 李方瑞 | Capsule 'Tangniaoshenkang' for treating diabetes |
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2016
- 2016-01-22 CN CN201610041027.4A patent/CN105477436A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1356117A (en) * | 2001-01-11 | 2002-07-03 | 李方瑞 | Capsule 'Tangniaoshenkang' for treating diabetes |
Non-Patent Citations (2)
| Title |
|---|
| 毛继祖 等: "《藏药方剂宝库》", 30 June 2014, 甘肃民族出版社 * |
| 罗达尚: "《新修晶珠本草》", 30 June 2004, 四川科学技术出版社 * |
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Application publication date: 20160413 |